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gamma-aminobutyric acid and Cancer-Associated Pain

gamma-aminobutyric acid has been researched along with Cancer-Associated Pain in 6 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Research Excerpts

ExcerptRelevanceReference
" The inclusion criteria are adult patients with cancer suffering from neuropathic cancer pain refractory to opioids and gabapentinoids, patients with a Numerical Rating Scale (NRS) pain score of 4 or higher and patients with a total Hospital Anxiety and Depression Scale score of less than 20."9.24Study protocol for a multi-institutional, randomised, double-blinded, placebo-controlled phase III trial investigating additive efficacy of duloxetine for neuropathic cancer pain refractory to opioids and gabapentinoids: the DIRECT study. ( Ariyoshi, K; Ishiki, H; Iwase, S; Kawaguchi, T; Kizawa, Y; Koyama, A; Matsuda, Y; Matsuoka, H; Miyaji, T; Morita, T; Yamaguchi, T, 2017)
"Gabapentin has been used as an adjuvant for treatment of cancer pain."9.22The research on long-term clinical effects and patients' satisfaction of gabapentin combined with oxycontin in treatment of severe cancer pain. ( Chen, DL; Li, YH; Wang, ZJ; Zhu, YK, 2016)
"Management of patients with cancer suffering from neuropathic pain refractory to opioids and gabapentinoids remains an important challenge."6.84Study protocol for a multi-institutional, randomised, double-blinded, placebo-controlled phase III trial investigating additive efficacy of duloxetine for neuropathic cancer pain refractory to opioids and gabapentinoids: the DIRECT study. ( Ariyoshi, K; Ishiki, H; Iwase, S; Kawaguchi, T; Kizawa, Y; Koyama, A; Matsuda, Y; Matsuoka, H; Miyaji, T; Morita, T; Yamaguchi, T, 2017)
"Gabapentin has been used as an adjuvant for treatment of cancer pain."6.82The research on long-term clinical effects and patients' satisfaction of gabapentin combined with oxycontin in treatment of severe cancer pain. ( Chen, DL; Li, YH; Wang, ZJ; Zhu, YK, 2016)
" Previous studies showed that opioids combined with gabapentin for management of cancer pain reduced the dosage of opioids."6.82The research on long-term clinical effects and patients' satisfaction of gabapentin combined with oxycontin in treatment of severe cancer pain. ( Chen, DL; Li, YH; Wang, ZJ; Zhu, YK, 2016)
" The inclusion criteria are adult patients with cancer suffering from neuropathic cancer pain refractory to opioids and gabapentinoids, patients with a Numerical Rating Scale (NRS) pain score of 4 or higher and patients with a total Hospital Anxiety and Depression Scale score of less than 20."5.24Study protocol for a multi-institutional, randomised, double-blinded, placebo-controlled phase III trial investigating additive efficacy of duloxetine for neuropathic cancer pain refractory to opioids and gabapentinoids: the DIRECT study. ( Ariyoshi, K; Ishiki, H; Iwase, S; Kawaguchi, T; Kizawa, Y; Koyama, A; Matsuda, Y; Matsuoka, H; Miyaji, T; Morita, T; Yamaguchi, T, 2017)
"Gabapentin has been used as an adjuvant for treatment of cancer pain."5.22The research on long-term clinical effects and patients' satisfaction of gabapentin combined with oxycontin in treatment of severe cancer pain. ( Chen, DL; Li, YH; Wang, ZJ; Zhu, YK, 2016)
"Management of patients with cancer suffering from neuropathic pain refractory to opioids and gabapentinoids remains an important challenge."2.84Study protocol for a multi-institutional, randomised, double-blinded, placebo-controlled phase III trial investigating additive efficacy of duloxetine for neuropathic cancer pain refractory to opioids and gabapentinoids: the DIRECT study. ( Ariyoshi, K; Ishiki, H; Iwase, S; Kawaguchi, T; Kizawa, Y; Koyama, A; Matsuda, Y; Matsuoka, H; Miyaji, T; Morita, T; Yamaguchi, T, 2017)
"Gabapentin has been used as an adjuvant for treatment of cancer pain."2.82The research on long-term clinical effects and patients' satisfaction of gabapentin combined with oxycontin in treatment of severe cancer pain. ( Chen, DL; Li, YH; Wang, ZJ; Zhu, YK, 2016)
" Previous studies showed that opioids combined with gabapentin for management of cancer pain reduced the dosage of opioids."2.82The research on long-term clinical effects and patients' satisfaction of gabapentin combined with oxycontin in treatment of severe cancer pain. ( Chen, DL; Li, YH; Wang, ZJ; Zhu, YK, 2016)
"Compared with nociceptive pain, neuropathic pain is a challenging diagnosis to make and successfully treat in children with cancer."1.46Very-Low-Dose Methadone To Treat Refractory Neuropathic Pain in Children with Cancer. ( Bruera, E; Madden, K, 2017)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Yeo, M1
Chen, Y1
Jiang, C1
Chen, G1
Wang, K1
Chandra, S1
Bortsov, A1
Lioudyno, M1
Zeng, Q1
Wang, P1
Wang, Z1
Busciglio, J1
Ji, RR1
Liedtke, W1
Corona-Ramos, JN1
Déciga-Campos, M1
Romero-Piña, M1
Medina, LA1
Martínez-Racine, I1
Jaramillo-Morales, OA1
García-López, P1
López-Muñoz, FJ1
Madden, K1
Bruera, E1
Matsuoka, H1
Ishiki, H1
Iwase, S1
Koyama, A1
Kawaguchi, T1
Kizawa, Y1
Morita, T1
Matsuda, Y1
Miyaji, T1
Ariyoshi, K1
Yamaguchi, T1
Ge, MM1
Chen, SP1
Zhou, YQ1
Li, Z1
Tian, XB1
Gao, F1
Manyande, A1
Tian, YK1
Yang, H1
Chen, DL1
Li, YH1
Wang, ZJ1
Zhu, YK1

Trials

2 trials available for gamma-aminobutyric acid and Cancer-Associated Pain

ArticleYear
Study protocol for a multi-institutional, randomised, double-blinded, placebo-controlled phase III trial investigating additive efficacy of duloxetine for neuropathic cancer pain refractory to opioids and gabapentinoids: the DIRECT study.
    BMJ open, 2017, Aug-28, Volume: 7, Issue:8

    Topics: Adult; Aged; Amines; Analgesics; Analgesics, Opioid; Cancer Pain; Cyclohexanecarboxylic Acids; Doubl

2017
The research on long-term clinical effects and patients' satisfaction of gabapentin combined with oxycontin in treatment of severe cancer pain.
    Medicine, 2016, Volume: 95, Issue:42

    Topics: Adult; Amines; Analgesics; Cancer Pain; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Dru

2016

Other Studies

4 other studies available for gamma-aminobutyric acid and Cancer-Associated Pain

ArticleYear
Repurposing cancer drugs identifies kenpaullone which ameliorates pathologic pain in preclinical models via normalization of inhibitory neurotransmission.
    Nature communications, 2021, 10-27, Volume: 12, Issue:1

    Topics: Action Potentials; Analgesics; Animals; Benzazepines; Cancer Pain; Catenins; Cells, Cultured; Delta

2021
The Effect of Gabapentin and Tramadol in Cancer Pain Induced by Glioma Cell in Rat Femur.
    Drug development research, 2017, Volume: 78, Issue:5

    Topics: Amines; Analgesics; Animals; Bone Neoplasms; Brain Neoplasms; Cancer Pain; Cell Line, Tumor; Cell Su

2017
Very-Low-Dose Methadone To Treat Refractory Neuropathic Pain in Children with Cancer.
    Journal of palliative medicine, 2017, Volume: 20, Issue:11

    Topics: Amines; Analgesics; Analgesics, Opioid; Cancer Pain; Child; Child, Preschool; Chronic Pain; Cyclohex

2017
The therapeutic potential of GABA in neuron-glia interactions of cancer-induced bone pain.
    European journal of pharmacology, 2019, Sep-05, Volume: 858

    Topics: Animals; Bone Neoplasms; Cancer Pain; Cell Communication; Cell Line, Tumor; Female; GABA Plasma Memb

2019