Page last updated: 2024-10-15

gamma-aminobutyric acid and Burning Mouth Syndrome

gamma-aminobutyric acid has been researched along with Burning Mouth Syndrome in 13 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Burning Mouth Syndrome: A group of painful oral symptoms associated with a burning or similar sensation. There is usually a significant organic component with a degree of functional overlay; it is not limited to the psychophysiologic group of disorders.

Research Excerpts

ExcerptRelevanceReference
"Burning mouth syndrome is a debilitating disorder involving oral pain that may have at least 4 underlying causes."5.32Effectiveness of gabapentin for treatment of burning mouth syndrome. ( Emko, P; Kent, PF; Kurtz, DB; White, TL, 2004)
"Gabapentin was seen in one study to work alone and synergistically with ALA."2.58Burning mouth syndrome: a systematic review of treatments. ( Han, P; Inman, JC; Kim, Y; Liu, YF; Yoo, T, 2018)
"Burning mouth syndrome is a debilitating disorder involving oral pain that may have at least 4 underlying causes."1.32Effectiveness of gabapentin for treatment of burning mouth syndrome. ( Emko, P; Kent, PF; Kurtz, DB; White, TL, 2004)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (46.15)29.6817
2010's7 (53.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tan, SN1
Song, E1
Dong, XD1
Somvanshi, RK1
Cairns, BE1
Liu, YF1
Kim, Y1
Yoo, T1
Han, P1
Inman, JC1
Pigatto, PD1
Guzzi, G1
López, V1
Alonso, V1
Martí, N1
Calduch, L1
Jordá, E1
López-D'alessandro, E1
Escovich, L1
de Tommaso, M1
Lavolpe, V1
Di Venere, D1
Corsalini, M1
Vecchio, E1
Favia, G1
Sardaro, M1
Livrea, P1
Nolano, M1
Martin, WJ1
Forouzanfar, T1
Forssell, H1
Teerijoki-Oksa, T1
Kotiranta, U1
Kantola, R1
Bäck, M1
Vuorjoki-Ranta, TR1
Siponen, M1
Leino, A1
Puukka, P1
Estlander, AM1
Gerlinger, I1
White, TL1
Kent, PF1
Kurtz, DB1
Emko, P1
Bartoshuk, LM1
Snyder, DJ1
Grushka, M1
Berger, AM1
Duffy, VB1
Kveton, JF1
Heckmann, SM1
Heckmann, JG1
Ungethüm, A1
Hujoel, P1
Hummel, T1
Scardina, GA1
Pisano, T1
Messina, P1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective Study on the Treatment of Burning Mouth Syndrome With Integration of Traditional Chinese Medicine(TCM) and Western Medicine Based on TCM Syndrome Differentiation[NCT04189367]Phase 380 participants (Anticipated)Interventional2020-06-20Not yet recruiting
Efficacy of Gabapentin for Post-Covid-19 Olfactory Dysfunction[NCT05184192]Phase 250 participants (Anticipated)Interventional2022-01-10Enrolling by invitation
Burning Mouth Disorder (BMD) - a Neuropathic Pain Disorder? An Investigation Using Qualitative and Quantitative Sensory Testing (QST)[NCT00504387]12 participants (Anticipated)Observational2007-04-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for gamma-aminobutyric acid and Burning Mouth Syndrome

ArticleYear
Burning mouth syndrome: a systematic review of treatments.
    Oral diseases, 2018, Volume: 24, Issue:3

    Topics: Amines; Analgesics; Antioxidants; Burning Mouth Syndrome; Capsaicin; Clonazepam; Cyclohexanecarboxyl

2018
The efficacy of anticonvulsants on orofacial pain: a systematic review.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2011, Volume: 111, Issue:5

    Topics: Amines; Anticonvulsants; Burning Mouth Syndrome; Carbamazepine; Clonazepam; Cyclohexanecarboxylic Ac

2011
[Burning sensation in oral cavity--burning mouth syndrome in everyday medical practice].
    Ideggyogyaszati szemle, 2012, Sep-30, Volume: 65, Issue:9-10

    Topics: Acetamides; Amines; Anti-Anxiety Agents; Antidepressive Agents; Antioxidants; Burning Mouth Syndrome

2012
[Burning mouth syndrome].
    Recenti progressi in medicina, 2007, Volume: 98, Issue:2

    Topics: Age Factors; Aged; Amines; Analgesics; Anti-Anxiety Agents; Antioxidants; Burning Mouth Syndrome; Cl

2007

Trials

1 trial available for gamma-aminobutyric acid and Burning Mouth Syndrome

ArticleYear
Combination of alpha lipoic acid and gabapentin, its efficacy in the treatment of Burning Mouth Syndrome: a randomized, double-blind, placebo controlled trial.
    Medicina oral, patologia oral y cirugia bucal, 2011, Aug-01, Volume: 16, Issue:5

    Topics: Amines; Burning Mouth Syndrome; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Double-Blind

2011

Other Studies

8 other studies available for gamma-aminobutyric acid and Burning Mouth Syndrome

ArticleYear
Peripheral GABAA receptor activation modulates rat tongue afferent mechanical sensitivity.
    Archives of oral biology, 2014, Volume: 59, Issue:3

    Topics: Administration, Topical; Animals; Benzodiazepines; Burning Mouth Syndrome; Disease Models, Animal; F

2014
Neuropathic pain in children after exposure to mercury.
    Paediatric anaesthesia, 2008, Volume: 18, Issue:12

    Topics: Amines; Analgesics, Non-Narcotic; Burning Mouth Syndrome; Child; Cyclohexanecarboxylic Acids; Gabape

2008
Marked response of burning mouth syndrome to pregabalin treatment.
    Clinical and experimental dermatology, 2009, Volume: 34, Issue:7

    Topics: Analgesics, Non-Narcotic; Burning Mouth Syndrome; Female; gamma-Aminobutyric Acid; Humans; Middle Ag

2009
A case of unilateral burning mouth syndrome of neuropathic origin.
    Headache, 2011, Volume: 51, Issue:3

    Topics: Aged; Analgesics; Anesthesia, Dental; Biopsy; Burning Mouth Syndrome; gamma-Aminobutyric Acid; Human

2011
Pain and pain behavior in burning mouth syndrome: a pain diary study.
    Journal of orofacial pain, 2012,Spring, Volume: 26, Issue:2

    Topics: Adaptation, Psychological; Analgesics; Analysis of Variance; Anticonvulsants; Antidepressive Agents,

2012
Effectiveness of gabapentin for treatment of burning mouth syndrome.
    Archives of otolaryngology--head & neck surgery, 2004, Volume: 130, Issue:6

    Topics: Acetates; Aged; Amines; Burning Mouth Syndrome; Cyclohexanecarboxylic Acids; Female; GABA Agonists;

2004
Taste damage: previously unsuspected consequences.
    Chemical senses, 2005, Volume: 30 Suppl 1

    Topics: Burning Mouth Syndrome; Clonazepam; Female; GABA Agonists; gamma-Aminobutyric Acid; Humans; Male; Mo

2005
Gabapentin has little or no effect in the treatment of burning mouth syndrome - results of an open-label pilot study.
    European journal of neurology, 2006, Volume: 13, Issue:7

    Topics: Aged; Amines; Burning Mouth Syndrome; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Female;

2006