gamma-aminobutyric acid has been researched along with Brain Injuries in 84 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gamma-aminobutyric acid (GABA) and glutamatergic system perturbations following premature birth may explain neurodevelopmental deficits in the absence of structural brain injury." | 4.31 | Severity of prematurity and age impact early postnatal development of GABA and glutamate systems. ( Andescavage, N; Basu, SK; Chang, T; duPlessis, AJ; Kapse, KJ; Limperopoulos, C; Lopez, CA; Murnick, J; Pradhan, S; Sharker, YM, 2023) |
| "Recurrent seizures (RS) were induced by flurothyl inhalation in immature rats." | 3.96 | Recurrent seizures cause immature brain injury and changes in GABA a receptor α1 and γ2 subunits. ( Feng, J; Hu, XY; Shi, XY; Tang, JH; Wan, Y; Xi, XJ; Zhang, BB; Zhou, C, 2020) |
| "A study of 246 patients (with schizophrenia, manic depressive psychoses and psychoorganic syndrome) treated by some drugs of a metabolic action (encephalotropic", "nootropic" drugs, piracetam, piriditol and pantogam) permitted one to determine the place of these preparations in a comprehensive treatment of mental disorders." | 3.66 | [Certain principles for differential utilization of metabolic treatment preparations in the complex therapy of mental disorders]. ( Avrutskiĭ, GIa; Laskova, NB, 1979) |
| " After three doses, median Cmax in microdialysates increased to 5." | 2.79 | Monitoring vigabatrin in head injury patients by cerebral microdialysis: obtaining pharmacokinetic measurements in a neurocritical care setting. ( Carpenter, KL; Hutchinson, PJ; Nortje, J; Shannon, RJ; Timofeev, I, 2014) |
| "Acquired brain injury can cause eye movement disorders which may include: strabismus, gaze deficits and nystagmus, causing visual symptoms of double, blurred or 'juddery' vision and reading difficulties." | 2.58 | Interventions for eye movement disorders due to acquired brain injury. ( Dodridge, CS; Evans, JR; Garcia-Finana, M; Hanna, K; Howard, C; Jarvis, KA; Maan, T; MacDiarmid, SL; Noonan, CP; North, L; Rodgers, H; Rowe, FJ, 2018) |
| "Epilepsy is a disorder of recurrent seizures that are neural in origin." | 2.40 | Seizures: classification, etiologies, and pathophysiology. ( March, PA, 1998) |
| "Partial seizures are usually due to a structural cerebrocortical lesion and may be simple or complex." | 2.40 | Seizures: classification, etiologies, and pathophysiology. ( March, PA, 1998) |
| "Recurrent seizures (RS) were induced by flurothyl inhalation in immature rats." | 1.56 | Recurrent seizures cause immature brain injury and changes in GABA a receptor α1 and γ2 subunits. ( Feng, J; Hu, XY; Shi, XY; Tang, JH; Wan, Y; Xi, XJ; Zhang, BB; Zhou, C, 2020) |
| "Macroglossia has been reported in patients undergoing posterior fossa neurosurgical procedures and is thought to be as a result of venous engorgement from intubation or mechanical positioning during these prolonged procedures." | 1.40 | Macroglossia associated with brainstem injury. ( Ardelt, A; Cueva, W; Frank, J; Goldenberg, F; Iwuchukwu, I; Reshi, R, 2014) |
| "Macroglossia was managed with dexamethasone and there was complete resolution of dysautonomia while treated with beta-blockers and gabapentin." | 1.40 | Macroglossia associated with brainstem injury. ( Ardelt, A; Cueva, W; Frank, J; Goldenberg, F; Iwuchukwu, I; Reshi, R, 2014) |
| "Early treatment of epilepsy is warranted to avoid possible severe consequences." | 1.39 | Epilepsy and brain injury: a case report of a dramatic neuropsychiatric vicious circle. ( Angeletti, G; Carbonetti, P; Del Casale, A; Fensore, C; Ferracuti, S; Girardi, P; Kotzalidis, GD; Lazanio, S; Muzi, A; Rapinesi, C; Savoja, V; Scatena, P; Serata, D; Tatarelli, R, 2013) |
| "Long-term untreated epilepsy may expose to accident proneness and further psychiatric deterioration." | 1.39 | Epilepsy and brain injury: a case report of a dramatic neuropsychiatric vicious circle. ( Angeletti, G; Carbonetti, P; Del Casale, A; Fensore, C; Ferracuti, S; Girardi, P; Kotzalidis, GD; Lazanio, S; Muzi, A; Rapinesi, C; Savoja, V; Scatena, P; Serata, D; Tatarelli, R, 2013) |
| "Intracranial stab wounds are low-velocity, penetrating injuries to the brain and fatality and outcome significantly depend on route, depth and location of cranial penetration." | 1.39 | Self-inflicted trans-oral intracranial stab wound. ( Han, ZA; Kim, JH; Kim, SW, 2013) |
| "Mean pre-withdrawal pregabalin dosage was 386 mg/day, decreasing to 70 mg/day at mean lowest dosage." | 1.39 | Spasticity increases during pregabalin withdrawal. ( Baguley, IJ; Braid, JJ; Kirker, SG, 2013) |
| "Median subjective spasticity scores increased from 4 at baseline to 6 at lowest dose (p < 0." | 1.39 | Spasticity increases during pregabalin withdrawal. ( Baguley, IJ; Braid, JJ; Kirker, SG, 2013) |
| "Gabapentin (GBP) is an anticonvulsant that acts at the α2δ-1 submit of the L-type calcium channel." | 1.38 | Gabapentin decreases epileptiform discharges in a chronic model of neocortical trauma. ( Barres, BA; Graber, KD; Jin, S; Li, H; McDonald, W; Prince, DA, 2012) |
| " These results indicate that chronic administration of GBP after cortical injury is antiepileptogenic in the undercut model of post-traumatic epilepsy, perhaps by both neuroprotective actions and decreases in excitatory synapse formation." | 1.38 | Gabapentin decreases epileptiform discharges in a chronic model of neocortical trauma. ( Barres, BA; Graber, KD; Jin, S; Li, H; McDonald, W; Prince, DA, 2012) |
| " For this purpose we conducted a dose-response study at concentrations of AMPA between 0." | 1.35 | Pattern of injury with a graded excitotoxic insult and ensuing chronic medial septal damage in the rat brain. ( Andrés, N; Batlle, M; Mahy, N; Malpesa, Y; Prats, A; Pugliese, M; Rodríguez, MJ, 2009) |
| "Paroxysmal autonomic instability with dystonia, an under-recognized and poorly understood phenomenon of episodic central dysautonomia is associated with various cerebral insults." | 1.34 | Paroxysmal autonomic instability with dystonia. ( Lim, CC; Srinivasan, S; Thirugnanam, U, 2007) |
| "The severe burning pain, deep pressure-like pain, and deep mechanical allodynia, which presented over the contralateral side to the TBI, were successfully relieved with motor cortex stimulation (MCS)." | 1.33 | Motor cortex stimulation for central pain following a traumatic brain injury. ( Choi, ES; Hong, JT; Lee, SW; Son, BC; Sung, JH, 2006) |
| "Nonconvulsive seizures (NCSs) after traumatic and ischemic brain injury are often refractory to antiepileptic drug therapy and are associated with a decline in patient outcome." | 1.32 | Antiepileptic drug treatment of nonconvulsive seizures induced by experimental focal brain ischemia. ( Hartings, JA; Lu, XM; Moreton, JE; Tortella, FC; Williams, AJ, 2004) |
| " In the Morris water maze, contused rats treated with gacyclidine at a dosage of 0." | 1.31 | Effects of the novel NMDA receptor antagonist gacyclidine on recovery from medial frontal cortex contusion injury in rats. ( Darrell, RS; Fulop, ZL; Levinsohn, SA; Smith, JS; Stein, DG, 2000) |
| "3." | 1.29 | Neuroprotection by propofol in acute mechanical injury: role of GABAergic inhibition. ( Hollrigel, GS; Soltesz, I; Toth, K, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (11.90) | 18.7374 |
| 1990's | 12 (14.29) | 18.2507 |
| 2000's | 24 (28.57) | 29.6817 |
| 2010's | 31 (36.90) | 24.3611 |
| 2020's | 7 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, X | 2 |
| Yang, F | 1 |
| Deng, L | 1 |
| Qiu, D | 1 |
| Liu, Y | 1 |
| Kang, Y | 1 |
| Gao, Y | 1 |
| Dong, J | 1 |
| Chen, M | 1 |
| Wang, T | 1 |
| Yang, Z | 1 |
| He, K | 1 |
| Li, Y | 1 |
| Wang, K | 1 |
| Jiang, J | 2 |
| Zhang, S | 1 |
| Liu, C | 3 |
| He, P | 3 |
| Guo, Y | 3 |
| Tian, Q | 3 |
| Wang, J | 3 |
| Wang, G | 3 |
| Zhang, Z | 3 |
| Li, M | 3 |
| Basu, SK | 2 |
| Pradhan, S | 2 |
| Sharker, YM | 1 |
| Kapse, KJ | 2 |
| Murnick, J | 2 |
| Chang, T | 1 |
| Lopez, CA | 1 |
| Andescavage, N | 2 |
| duPlessis, AJ | 1 |
| Limperopoulos, C | 2 |
| Spoehr, E | 1 |
| Zhang, A | 1 |
| Nino, G | 1 |
| du Plessis, AJ | 1 |
| Xi, XJ | 1 |
| Tang, JH | 1 |
| Zhang, BB | 1 |
| Shi, XY | 1 |
| Feng, J | 1 |
| Hu, XY | 1 |
| Wan, Y | 1 |
| Zhou, C | 1 |
| Ramos-Languren, LE | 1 |
| Avila-Luna, A | 1 |
| García-Díaz, G | 1 |
| Rodríguez-Labrada, R | 1 |
| Vázquez-Mojena, Y | 1 |
| Parra-Cid, C | 1 |
| Montes, S | 1 |
| Bueno-Nava, A | 1 |
| González-Piña, R | 1 |
| Rowe, FJ | 1 |
| Hanna, K | 1 |
| Evans, JR | 1 |
| Noonan, CP | 1 |
| Garcia-Finana, M | 1 |
| Dodridge, CS | 1 |
| Howard, C | 1 |
| Jarvis, KA | 1 |
| MacDiarmid, SL | 1 |
| Maan, T | 1 |
| North, L | 1 |
| Rodgers, H | 1 |
| Yamada, H | 1 |
| Kikuchi, R | 1 |
| Katayama, J | 1 |
| Nakamura, A | 1 |
| Miyazaki, H | 1 |
| Belozertsev, IuA | 1 |
| Zapol'skaia, IuA | 1 |
| Belozertsev, FIu | 1 |
| Iuntsev, SV | 1 |
| Rapinesi, C | 1 |
| Del Casale, A | 1 |
| Serata, D | 1 |
| Kotzalidis, GD | 1 |
| Scatena, P | 1 |
| Muzi, A | 1 |
| Lazanio, S | 1 |
| Savoja, V | 1 |
| Carbonetti, P | 1 |
| Fensore, C | 1 |
| Ferracuti, S | 1 |
| Angeletti, G | 1 |
| Tatarelli, R | 1 |
| Girardi, P | 1 |
| Kim, SW | 1 |
| Kim, JH | 1 |
| Han, ZA | 1 |
| Iwuchukwu, I | 1 |
| Ardelt, A | 1 |
| Cueva, W | 1 |
| Reshi, R | 1 |
| Goldenberg, F | 1 |
| Frank, J | 1 |
| Hendrickson, A | 1 |
| Warner, CE | 1 |
| Possin, D | 1 |
| Huang, J | 1 |
| Kwan, WC | 1 |
| Bourne, JA | 1 |
| Sajja, VS | 2 |
| Perrine, SA | 1 |
| Ghoddoussi, F | 1 |
| Hall, CS | 1 |
| Galloway, MP | 1 |
| VandeVord, PJ | 2 |
| Kiss, JZ | 1 |
| Vasung, L | 1 |
| Petrenko, V | 1 |
| Shannon, RJ | 1 |
| Timofeev, I | 3 |
| Nortje, J | 2 |
| Hutchinson, PJ | 2 |
| Carpenter, KL | 2 |
| Tatarishvili, J | 1 |
| Oki, K | 1 |
| Monni, E | 1 |
| Koch, P | 1 |
| Memanishvili, T | 1 |
| Buga, AM | 1 |
| Verma, V | 1 |
| Popa-Wagner, A | 1 |
| Brüstle, O | 1 |
| Lindvall, O | 1 |
| Kokaia, Z | 1 |
| Almeida-Suhett, CP | 1 |
| Prager, EM | 1 |
| Pidoplichko, V | 1 |
| Figueiredo, TH | 1 |
| Marini, AM | 1 |
| Li, Z | 1 |
| Eiden, LE | 1 |
| Braga, MF | 1 |
| Fievisohn, EM | 1 |
| Hardy, WN | 1 |
| Guerriero, RM | 1 |
| Giza, CC | 1 |
| Rotenberg, A | 1 |
| Zhivolupov, SA | 1 |
| Bardakov, SN | 1 |
| Samartsev, IN | 1 |
| Ponomarev, VV | 1 |
| Guan, YF | 1 |
| Wu, CY | 1 |
| Fang, YY | 1 |
| Zeng, YN | 1 |
| Luo, ZY | 1 |
| Li, SJ | 1 |
| Li, XW | 1 |
| Zhu, XH | 1 |
| Mei, L | 1 |
| Gao, TM | 1 |
| Klein, KU | 1 |
| Johannes, A | 1 |
| Brückner, M | 1 |
| Thomas, R | 1 |
| Matthews, S | 1 |
| Frauenknecht, K | 1 |
| Leukel, P | 1 |
| Mazur, J | 1 |
| Poplawski, A | 1 |
| Muellenbach, R | 1 |
| Sommer, CJ | 1 |
| Thal, SC | 1 |
| Engelhard, K | 1 |
| Shulga, A | 2 |
| Thomas-Crusells, J | 1 |
| Sigl, T | 1 |
| Blaesse, A | 1 |
| Mestres, P | 1 |
| Meyer, M | 1 |
| Yan, Q | 1 |
| Kaila, K | 1 |
| Saarma, M | 1 |
| Rivera, C | 2 |
| Giehl, KM | 1 |
| Sargin, D | 1 |
| Hassouna, I | 1 |
| Sperling, S | 1 |
| Sirén, AL | 1 |
| Ehrenreich, H | 1 |
| Prince, DA | 2 |
| Parada, I | 1 |
| Scalise, K | 1 |
| Graber, K | 1 |
| Jin, X | 1 |
| Shen, F | 1 |
| Avramescu, S | 1 |
| Nita, DA | 1 |
| Rodríguez, MJ | 1 |
| Prats, A | 1 |
| Malpesa, Y | 1 |
| Andrés, N | 1 |
| Pugliese, M | 1 |
| Batlle, M | 1 |
| Mahy, N | 1 |
| Ochalski, PG | 1 |
| Fellows-Mayle, W | 1 |
| Hsieh, LB | 1 |
| Srinivas, R | 1 |
| Okonkwo, DO | 1 |
| Dixon, CE | 1 |
| Adelson, PD | 1 |
| Andersson, DR | 1 |
| Björnsson, E | 1 |
| Bergquist, F | 1 |
| Nissbrandt, H | 1 |
| De Bartolo, P | 1 |
| Cutuli, D | 1 |
| Ricceri, L | 1 |
| Gelfo, F | 1 |
| Foti, F | 1 |
| Laricchiuta, D | 1 |
| Scattoni, ML | 1 |
| Calamandrei, G | 1 |
| Petrosini, L | 1 |
| Skoromets, AA | 1 |
| Pugacheva, EL | 1 |
| Calabrò, RS | 1 |
| Bramanti, P | 1 |
| Lee, S | 1 |
| Ueno, M | 1 |
| Yamashita, T | 1 |
| Hunt, RF | 1 |
| Scheff, SW | 1 |
| Smith, BN | 1 |
| Grimmelt, AC | 1 |
| Eitzen, S | 1 |
| Balakhadze, I | 1 |
| Fischer, B | 1 |
| Wölfer, J | 1 |
| Schiffbauer, H | 1 |
| Gorji, A | 1 |
| Greiner, C | 1 |
| Imbrosci, B | 1 |
| Mittmann, T | 1 |
| Czosnyka, M | 1 |
| Pickard, JD | 1 |
| Dzhala, V | 1 |
| Valeeva, G | 1 |
| Glykys, J | 1 |
| Khazipov, R | 1 |
| Staley, K | 1 |
| Li, H | 1 |
| Graber, KD | 1 |
| Jin, S | 1 |
| McDonald, W | 1 |
| Barres, BA | 1 |
| Braid, JJ | 1 |
| Kirker, SG | 1 |
| Baguley, IJ | 2 |
| BERTAMINO, F | 1 |
| VENTO, R | 1 |
| Williams, AJ | 1 |
| Tortella, FC | 1 |
| Lu, XM | 1 |
| Moreton, JE | 1 |
| Hartings, JA | 1 |
| Deukmedjian, AJ | 1 |
| King, MA | 1 |
| Cuda, C | 1 |
| Roper, SN | 1 |
| Stuckey, DJ | 1 |
| Anthony, DC | 1 |
| Lowe, JP | 1 |
| Miller, J | 1 |
| Palm, WM | 1 |
| Styles, P | 1 |
| Perry, VH | 1 |
| Blamire, AM | 1 |
| Sibson, NR | 1 |
| Gerstein, M | 1 |
| Huleihel, M | 1 |
| Mane, R | 1 |
| Stilman, M | 1 |
| Kashtuzki, I | 1 |
| Hallak, M | 1 |
| Golan, H | 1 |
| Pérez-De La Cruz, V | 1 |
| González-Cortés, C | 1 |
| Galván-Arzate, S | 1 |
| Medina-Campos, ON | 1 |
| Pérez-Severiano, F | 1 |
| Ali, SF | 1 |
| Pedraza-Chaverrí, J | 1 |
| Santamaría, A | 1 |
| Zhong, C | 1 |
| Zhao, X | 1 |
| Van, KC | 1 |
| Bzdega, T | 1 |
| Smyth, A | 1 |
| Zhou, J | 1 |
| Kozikowski, AP | 1 |
| O'Connor, WT | 1 |
| Berman, RF | 1 |
| Neale, JH | 1 |
| Lyeth, BG | 2 |
| Son, BC | 1 |
| Lee, SW | 1 |
| Choi, ES | 1 |
| Sung, JH | 1 |
| Hong, JT | 1 |
| Yang, L | 2 |
| Benardo, LS | 2 |
| Valsamis, H | 1 |
| Ling, DS | 1 |
| Bonislawski, DP | 1 |
| Schwarzbach, EP | 1 |
| Cohen, AS | 1 |
| Neese, SL | 1 |
| Sherill, LK | 1 |
| Tan, AA | 1 |
| Roosevelt, RW | 1 |
| Browning, RA | 1 |
| Smith, DC | 1 |
| Duke, A | 1 |
| Clough, RW | 1 |
| Sun, Y | 1 |
| Godfrey, DA | 1 |
| Godfrey, TG | 1 |
| Rubin, AM | 1 |
| Becerra, GD | 1 |
| Tatko, LM | 1 |
| Pak, ES | 1 |
| Murashov, AK | 1 |
| Hoane, MR | 1 |
| Heriseanu, RE | 1 |
| Gurka, JA | 1 |
| Nordenbo, A | 1 |
| Cameron, ID | 1 |
| Srinivasan, S | 1 |
| Lim, CC | 1 |
| Thirugnanam, U | 1 |
| Mao, H | 1 |
| Toufexis, D | 1 |
| Lacreuse, A | 1 |
| Wu, S | 1 |
| Williams, C | 1 |
| Mallard, C | 1 |
| Tan, W | 1 |
| Johnston, B | 1 |
| Gunn, A | 1 |
| Marks, K | 1 |
| Gluckman, P | 1 |
| Kanthan, R | 1 |
| Shuaib, A | 1 |
| Leach, MJ | 1 |
| Swan, JH | 1 |
| Eisenthal, D | 1 |
| Dopson, M | 1 |
| Nobbs, M | 1 |
| Hollrigel, GS | 2 |
| Toth, K | 1 |
| Soltesz, I | 2 |
| Reeves, TM | 2 |
| Phillips, LL | 2 |
| Hamm, RJ | 1 |
| Povlishock, JT | 3 |
| Childers, MK | 1 |
| Holland, D | 1 |
| Toth, Z | 1 |
| Gorcs, T | 1 |
| Zhu, J | 1 |
| March, PA | 1 |
| Smith, JS | 1 |
| Fulop, ZL | 1 |
| Levinsohn, SA | 1 |
| Darrell, RS | 1 |
| Stein, DG | 1 |
| O'Dell, DM | 1 |
| Raghupathi, R | 1 |
| Crino, PB | 1 |
| Eberwine, JH | 1 |
| McIntosh, TK | 1 |
| Suzuki, M | 1 |
| Kudo, A | 1 |
| Sugawara, A | 1 |
| Yoshida, K | 1 |
| Kubo, Y | 1 |
| Suzuki, T | 1 |
| Ogasawara, K | 1 |
| Doi, M | 1 |
| Ogawa, A | 1 |
| Avrutskiĭ, GIa | 1 |
| Laskova, NB | 1 |
| Lukashevich, LP | 1 |
| Samosiuk, IZ | 1 |
| Filonchik, AA | 1 |
| Poemnyĭ, FA | 1 |
| Trubnikov, BM | 1 |
| Fodstad, H | 1 |
| Ljunggren, BC | 1 |
| Erb, DE | 1 |
| Lekomtsev, VT | 1 |
| Iasnetsov, VS | 1 |
| Novikov, VE | 1 |
| Hall, ED | 1 |
| McCall, JM | 1 |
| Chase, RL | 1 |
| Yonkers, PA | 1 |
| Braughler, JM | 1 |
| Roberts, E | 1 |
| Kretz, FJ | 1 |
| Löscher, W | 1 |
| Striebel, HW | 1 |
| Tobe, A | 1 |
| Egawa, M | 1 |
| Saito, K | 1 |
| Hashimoto, N | 1 |
| Borromei, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Examining the Effect of Eye Gaze Technology on Children With Cortical Visual Impairment and Its Impact on Occupational Performance[NCT06067607] | 10 participants (Anticipated) | Interventional | 2023-02-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 reviews available for gamma-aminobutyric acid and Brain Injuries
| Article | Year |
|---|---|
Interventions for eye movement disorders due to acquired brain injury.
Topics: 4-Aminopyridine; Abducens Nerve Diseases; Amifampridine; Amines; Baclofen; Botulinum Toxins; Brain I | 2018 |
Process of cortical network formation and impact of early brain damage.
Topics: Animals; Brain Injuries; Cerebral Cortex; gamma-Aminobutyric Acid; Humans; Interneurons; Nerve Net; | 2014 |
Glutamate and GABA imbalance following traumatic brain injury.
Topics: Animals; Brain Injuries; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid; Homeostasis; Humans; Rece | 2015 |
Epilepsy following cortical injury: cellular and molecular mechanisms as targets for potential prophylaxis.
Topics: Animals; Anticonvulsants; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Epilepsy, Post-Tr | 2009 |
Functional consequences of the disturbances in the GABA-mediated inhibition induced by injuries in the cerebral cortex.
Topics: Brain Injuries; Cerebral Cortex; gamma-Aminobutyric Acid; Humans; Neural Inhibition; Neurons; Synapt | 2011 |
Interplay between thyroxin, BDNF and GABA in injured neurons.
Topics: Animals; Brain Injuries; Brain-Derived Neurotrophic Factor; gamma-Aminobutyric Acid; Humans; Neurons | 2013 |
Seizures: classification, etiologies, and pathophysiology.
Topics: Animals; Brain Injuries; Cat Diseases; Cats; Cerebral Cortex; Dog Diseases; Dogs; Electroencephalogr | 1998 |
[Some therapeutic effects of GABA in neurology (author's transl)].
Topics: Aminobutyrates; Brain; Brain Diseases; Brain Injuries; Cerebrovascular Disorders; Coma; Epilepsy; ga | 1974 |
3 trials available for gamma-aminobutyric acid and Brain Injuries
| Article | Year |
|---|---|
Monitoring vigabatrin in head injury patients by cerebral microdialysis: obtaining pharmacokinetic measurements in a neurocritical care setting.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Area Under Curve; Blood-Brain Barrier; Brain Injuries; Chr | 2014 |
[Efficacy of the complex drug cytoflavin in the treatment of consequences of mild brain injury].
Topics: Adolescent; Adult; Brain Injuries; Drug Combinations; Flavin Mononucleotide; gamma-Aminobutyric Acid | 2010 |
A microdialysis study of oral vigabatrin administration in head injury patients: preliminary evaluation of multimodality monitoring.
Topics: Administration, Oral; Adolescent; Adult; Aged; Amino Acids; Anticonvulsants; Blood Pressure; Brain C | 2012 |
73 other studies available for gamma-aminobutyric acid and Brain Injuries
| Article | Year |
|---|---|
Liraglutide Is Protective against Brain Injury in Mice with Febrile Seizures by Inhibiting Inflammatory Factors.
Topics: Animals; Brain Injuries; gamma-Aminobutyric Acid; Glucagon-Like Peptide 1; Glutamates; Humans; Inter | 2022 |
Protective effect of low-dose radiation on doxorubicin-induced brain injury in mice.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Apoptosis; Brain Injuries; Doxorubicin; Female; gamma | 2022 |
Taurine attenuates neuronal ferroptosis by regulating GABA
Topics: beta Catenin; Brain Injuries; Ferroptosis; gamma-Aminobutyric Acid; Glycogen Synthase Kinase 3 beta; | 2022 |
Taurine attenuates neuronal ferroptosis by regulating GABA
Topics: beta Catenin; Brain Injuries; Ferroptosis; gamma-Aminobutyric Acid; Glycogen Synthase Kinase 3 beta; | 2022 |
Taurine attenuates neuronal ferroptosis by regulating GABA
Topics: beta Catenin; Brain Injuries; Ferroptosis; gamma-Aminobutyric Acid; Glycogen Synthase Kinase 3 beta; | 2022 |
Taurine attenuates neuronal ferroptosis by regulating GABA
Topics: beta Catenin; Brain Injuries; Ferroptosis; gamma-Aminobutyric Acid; Glycogen Synthase Kinase 3 beta; | 2022 |
Taurine attenuates neuronal ferroptosis by regulating GABA
Topics: beta Catenin; Brain Injuries; Ferroptosis; gamma-Aminobutyric Acid; Glycogen Synthase Kinase 3 beta; | 2022 |
Taurine attenuates neuronal ferroptosis by regulating GABA
Topics: beta Catenin; Brain Injuries; Ferroptosis; gamma-Aminobutyric Acid; Glycogen Synthase Kinase 3 beta; | 2022 |
Taurine attenuates neuronal ferroptosis by regulating GABA
Topics: beta Catenin; Brain Injuries; Ferroptosis; gamma-Aminobutyric Acid; Glycogen Synthase Kinase 3 beta; | 2022 |
Taurine attenuates neuronal ferroptosis by regulating GABA
Topics: beta Catenin; Brain Injuries; Ferroptosis; gamma-Aminobutyric Acid; Glycogen Synthase Kinase 3 beta; | 2022 |
Taurine attenuates neuronal ferroptosis by regulating GABA
Topics: beta Catenin; Brain Injuries; Ferroptosis; gamma-Aminobutyric Acid; Glycogen Synthase Kinase 3 beta; | 2022 |
Severity of prematurity and age impact early postnatal development of GABA and glutamate systems.
Topics: Brain Injuries; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Infant; Infant, Newborn; Inf | 2023 |
Impact of bronchopulmonary dysplasia on brain GABA concentrations in preterm infants: Prospective cohort study.
Topics: Brain; Brain Injuries; Bronchopulmonary Dysplasia; Female; Fetal Growth Retardation; gamma-Aminobuty | 2023 |
Recurrent seizures cause immature brain injury and changes in GABA a receptor α1 and γ2 subunits.
Topics: Animals; Brain; Brain Injuries; Epilepsy, Generalized; Female; Flurothyl; gamma-Aminobutyric Acid; H | 2020 |
Glutamate, Glutamine, GABA and Oxidative Products in the Pons Following Cortical Injury and Their Role in Motor Functional Recovery.
Topics: Animals; Brain Injuries; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Lipid Peroxidation; Male | 2021 |
Paroxysmal Sympathetic Hyperactivity after Surgery for Cerebral Hemorrhagic Arteriovenous Malformation: A Case Report.
Topics: Adolescent; Adrenergic beta-Antagonists; Amines; Autonomic Nervous System Diseases; Brain Injuries; | 2018 |
[Comparison of neuroprotective effects of anticonvulsant drugs in brain injury therapy].
Topics: Amines; Animals; Animals, Outbred Strains; Anticonvulsants; Brain; Brain Injuries; Brain Ischemia; C | 2012 |
Epilepsy and brain injury: a case report of a dramatic neuropsychiatric vicious circle.
Topics: Accidents, Traffic; Aggression; Amines; Anterior Temporal Lobectomy; Anticonvulsants; Brain Injuries | 2013 |
Self-inflicted trans-oral intracranial stab wound.
Topics: Amines; Analgesics; Antidepressive Agents; Brain Injuries; Cerebellum; Citalopram; Cyclohexanecarbox | 2013 |
Macroglossia associated with brainstem injury.
Topics: Adolescent; Adrenergic beta-Antagonists; Aged; Amines; Anti-Inflammatory Agents; Brain Injuries; Bra | 2014 |
Retrograde transneuronal degeneration in the retina and lateral geniculate nucleus of the V1-lesioned marmoset monkey.
Topics: Animals; Brain Injuries; Calbindin 1; Calbindin 2; Callithrix; gamma-Aminobutyric Acid; Geniculate B | 2015 |
Blast neurotrauma impairs working memory and disrupts prefrontal myo-inositol levels in rats.
Topics: Animals; Betaine; Blast Injuries; Brain Injuries; Creatine; Ethanolamines; gamma-Aminobutyric Acid; | 2014 |
Human induced pluripotent stem cells improve recovery in stroke-injured aged rats.
Topics: Aging; Analysis of Variance; Animals; Brain Injuries; Cell Differentiation; Disease Models, Animal; | 2014 |
Reduced GABAergic inhibition in the basolateral amygdala and the development of anxiety-like behaviors after mild traumatic brain injury.
Topics: Animals; Anxiety Disorders; Basolateral Nuclear Complex; Brain Injuries; gamma-Aminobutyric Acid; In | 2014 |
Evaluation of impact-induced traumatic brain injury in the Göttingen Minipig using two input modes.
Topics: Animals; Aspartic Acid; Brain Injuries; Dipeptides; Disease Models, Animal; Female; gamma-Aminobutyr | 2014 |
[Neurogenic copulative dysfunction in men: theoretical aspects, differential diagnosis, and rational therapy].
Topics: Adult; Brain Injuries; Diagnosis, Differential; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; | 2015 |
Neuregulin 1 protects against ischemic brain injury via ErbB4 receptors by increasing GABAergic transmission.
Topics: Animals; Apoptosis; Brain Injuries; Cell Hypoxia; Cells, Cultured; Disease Models, Animal; GABA Agon | 2015 |
Systemic PaO2 Oscillations Cause Mild Brain Injury in a Pig Model.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Blood Gas Analysis; Brain Injurie | 2016 |
Posttraumatic GABA(A)-mediated [Ca2+]i increase is essential for the induction of brain-derived neurotrophic factor-dependent survival of mature central neurons.
Topics: Animals; Animals, Newborn; Axons; Axotomy; Brain Injuries; Brain-Derived Neurotrophic Factor; Bumeta | 2008 |
Uncoupling of neurodegeneration and gliosis in a murine model of juvenile cortical lesion.
Topics: Animals; Astrocytes; Atrophy; Brain; Brain Injuries; Cold Temperature; Cyclic Nucleotide Phosphodies | 2009 |
Neocortical post-traumatic epileptogenesis is associated with loss of GABAergic neurons.
Topics: Animals; Brain Injuries; Cats; Cell Death; Craniotomy; Electrophysiology; Epilepsy; Female; gamma-Am | 2009 |
Pattern of injury with a graded excitotoxic insult and ensuing chronic medial septal damage in the rat brain.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Atroph | 2009 |
Flumazenil administration attenuates cognitive impairment in immature rats after controlled cortical impact.
Topics: Animals; Brain; Brain Chemistry; Brain Injuries; Cognition Disorders; Disease Models, Animal; Dose-R | 2010 |
Motor activity-induced dopamine release in the substantia nigra is regulated by muscarinic receptors.
Topics: Analysis of Variance; Animals; Area Under Curve; Brain Injuries; Chromatography, High Pressure Liqui | 2010 |
Does age matter? Behavioral and neuro-anatomical effects of neonatal and adult basal forebrain cholinergic lesions.
Topics: Acetylcholine; Age Factors; Aging; Analysis of Variance; Animals; Animals, Newborn; Antibodies, Mono | 2010 |
Pregabalin-induced severe delayed ejaculation.
Topics: Adult; Anticonvulsants; Brain Injuries; Epilepsy; Erectile Dysfunction; gamma-Aminobutyric Acid; Hum | 2010 |
Axonal remodeling for motor recovery after traumatic brain injury requires downregulation of γ-aminobutyric acid signaling.
Topics: Animals; Apoptosis Regulatory Proteins; Axons; Brain Injuries; Cerebral Cortex; Cytoskeletal Protein | 2011 |
Synaptic reorganization of inhibitory hilar interneuron circuitry after traumatic brain injury in mice.
Topics: Animals; Brain Injuries; Dentate Gyrus; Electrophysiology; Excitatory Postsynaptic Potentials; Femal | 2011 |
Closed traumatic brain injury model in sheep mimicking high-velocity, closed head trauma in humans.
Topics: Animals; Aspartic Acid; Brain; Brain Injuries; Carbon Dioxide; Disease Models, Animal; Electron Spin | 2011 |
Traumatic alterations in GABA signaling disrupt hippocampal network activity in the developing brain.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Age Factors; Animals; Animals, Newborn; Ant | 2012 |
Gabapentin decreases epileptiform discharges in a chronic model of neocortical trauma.
Topics: Amines; Animals; Anticonvulsants; Blotting, Western; Brain Injuries; Cyclohexanecarboxylic Acids; Di | 2012 |
Spasticity increases during pregabalin withdrawal.
Topics: Analgesics; Anticonvulsants; Brain Injuries; Cerebral Palsy; Drug Administration Schedule; Female; g | 2013 |
[GABOB IN PEDIATRICS. CLINICAL AND ELECTROENCEPHALOGRAPHIC STUDY OF 28 CASES].
Topics: Adolescent; Aminobutyrates; Barbiturates; Brain Injuries; Cerebral Palsy; Child; Electroencephalogra | 1964 |
Antiepileptic drug treatment of nonconvulsive seizures induced by experimental focal brain ischemia.
Topics: Amines; Animals; Anticonvulsants; Brain Infarction; Brain Injuries; Brain Ischemia; Cyclohexanecarbo | 2004 |
The GABAergic system of the developing neocortex has a reduced capacity to recover from in utero injury in experimental cortical dysplasia.
Topics: Animals; Animals, Newborn; Brain Injuries; Cell Count; Embryo, Mammalian; Female; gamma-Aminobutyric | 2004 |
Detection of the inhibitory neurotransmitter GABA in macrophages by magnetic resonance spectroscopy.
Topics: Amino Acids; Animals; Biomarkers; Brain Injuries; Cell Communication; Cell Extracts; Cell Line; Cell | 2005 |
Remodeling of hippocampal GABAergic system in adult offspring after maternal hypoxia and magnesium sulfate load: immunohistochemical study.
Topics: Animals; Brain Injuries; Calbindins; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hippo | 2005 |
Excitotoxic brain damage involves early peroxynitrite formation in a model of Huntington's disease in rats: protective role of iron porphyrinate 5,10,15,20-tetrakis (4-sulfonatophenyl)porphyrinate iron (III).
Topics: Analysis of Variance; Animals; Behavior, Animal; Blotting, Southern; Brain Injuries; Caspase 3; Casp | 2005 |
NAAG peptidase inhibitor increases dialysate NAAG and reduces glutamate, aspartate and GABA levels in the dorsal hippocampus following fluid percussion injury in the rat.
Topics: Animals; Aspartic Acid; Brain Injuries; Cytoprotection; Dipeptides; Disease Models, Animal; Down-Reg | 2006 |
Motor cortex stimulation for central pain following a traumatic brain injury.
Topics: Accidental Falls; Adult; Amines; Amitriptyline; Analgesics, Non-Narcotic; Aphasia, Broca; Brain Inju | 2006 |
Acute injury to superficial cortex leads to a decrease in synaptic inhibition and increase in excitation in neocortical layer V pyramidal cells.
Topics: Acute Disease; Animals; Brain Injuries; Disease Models, Animal; Epilepsy; Excitatory Postsynaptic Po | 2007 |
Brain injury impairs dentate gyrus inhibitory efficacy.
Topics: Animals; Blotting, Western; Brain Injuries; Chlorides; Dentate Gyrus; Electrophysiology; Fluorescent | 2007 |
Vagus nerve stimulation may protect GABAergic neurons following traumatic brain injury in rats: An immunocytochemical study.
Topics: Animals; Brain Injuries; Cell Count; Disease Models, Animal; Electric Stimulation; gamma-Aminobutyri | 2007 |
Changes of amino acid concentrations in the rat vestibular nuclei after inferior cerebellar peduncle transection.
Topics: Amino Acids; Animals; Brain Injuries; Cerebellum; Chromatography, High Pressure Liquid; gamma-Aminob | 2007 |
Transplantation of GABAergic neurons but not astrocytes induces recovery of sensorimotor function in the traumatically injured brain.
Topics: Analysis of Variance; Animals; Astrocytes; Brain Injuries; Brain Tissue Transplantation; Cell Differ | 2007 |
Gabapentin in the management of dysautonomia following severe traumatic brain injury: a case series.
Topics: Adolescent; Adult; Amines; Anticonvulsants; Autonomic Nervous System Diseases; Brain Injuries; Cyclo | 2007 |
Paroxysmal autonomic instability with dystonia.
Topics: Adult; Amines; Autonomic Nervous System Diseases; Benzodiazepines; Brain Injuries; Cyclohexanecarbox | 2007 |
Changes of metabolite profile in kainic acid induced hippocampal injury in rats measured by HRMAS NMR.
Topics: Amino Acids; Animals; Brain Injuries; Excitatory Amino Acid Agonists; Excitatory Amino Acids; gamma- | 2007 |
Perinatal brain injury. Pathophysiology and therapeutic intervention.
Topics: Animals; Animals, Newborn; Brain; Brain Injuries; Electroencephalography; Fetal Diseases; Flunarizin | 1995 |
Clinical evaluation of extracellular amino acids in severe head trauma by intracerebral in vivo microdialysis.
Topics: Adult; Brain Chemistry; Brain Injuries; Chromatography, High Pressure Liquid; gamma-Aminobutyric Aci | 1995 |
BW619C89, a glutamate release inhibitor, protects against focal cerebral ischemic damage.
Topics: Acetylcholine; Amino Acids; Animals; Blood Pressure; Brain Injuries; Brain Ischemia; Cerebral Cortex | 1993 |
Neuroprotection by propofol in acute mechanical injury: role of GABAergic inhibition.
Topics: Acute Disease; Anesthetics, Intravenous; Animals; Brain Injuries; Dendrites; gamma-Aminobutyric Acid | 1996 |
The effects of traumatic brain injury on inhibition in the hippocampus and dentate gyrus.
Topics: Animals; Brain Injuries; Dentate Gyrus; Electric Stimulation; Evoked Potentials; Functional Laterali | 1997 |
Psychomotor agitation following gabapentin use in brain injury.
Topics: Acetates; Adult; Akathisia, Drug-Induced; Amines; Analgesics; Brain Injuries; Cyclohexanecarboxylic | 1997 |
Instantaneous perturbation of dentate interneuronal networks by a pressure wave-transient delivered to the neocortex.
Topics: Animals; Brain Injuries; Cholecystokinin; Dentate Gyrus; Down-Regulation; Epilepsy; gamma-Aminobutyr | 1997 |
The effect of combined fluid percussion and entorhinal cortical lesions on long-term potentiation.
Topics: Animals; Brain Injuries; Electric Stimulation; Electrodes, Implanted; Electrophysiology; Entorhinal | 1997 |
Effects of the novel NMDA receptor antagonist gacyclidine on recovery from medial frontal cortex contusion injury in rats.
Topics: Animals; Basal Nucleus of Meynert; Brain Injuries; Cell Count; Cerebral Cortex; Cerebral Ventricles; | 2000 |
Traumatic brain injury alters the molecular fingerprint of TUNEL-positive cortical neurons In vivo: A single-cell analysis.
Topics: Animals; Apoptosis; Brain Injuries; Caspase 2; Caspases; Cell Death; Cerebral Cortex; Cyclic AMP Res | 2000 |
Valproate prevents epileptiform activity after trauma in an in vitro model in neocortical slices.
Topics: Animals; Anticonvulsants; Brain Injuries; Disease Models, Animal; Epilepsy; gamma-Aminobutyric Acid; | 2000 |
Amino acid concentrations in the blood of the jugular vein and peripheral artery after traumatic brain injury: decreased release of glutamate into the jugular vein in the early phase.
Topics: Adolescent; Adult; Aged; Amino Acids; Arteries; Aspartic Acid; Brain Injuries; Cystine; Female; gamm | 2002 |
[Certain principles for differential utilization of metabolic treatment preparations in the complex therapy of mental disorders].
Topics: Adolescent; Adult; Aged; Bipolar Disorder; Brain Injuries; gamma-Aminobutyric Acid; Humans; Infectio | 1979 |
[Use of certain preparations of gamma-aminobutyric acid in diseases of the nervous system].
Topics: Adolescent; Adult; Aged; Aminobutyrates; Brain Injuries; Cerebrovascular Disorders; Child; Drug Eval | 1975 |
[Treatment of infectious-toxic and traumatic lesion, of the hypothalamic region with aminalon and gammalon].
Topics: Adult; Aminobutyrates; Brain Diseases; Brain Injuries; Epilepsy; Female; gamma-Aminobutyric Acid; Hu | 1975 |
Baclofen and carbamazepine in supraspinal spasticity.
Topics: Administration, Oral; Adult; Baclofen; Brain Injuries; Carbamazepine; Drug Therapy, Combination; Fem | 1991 |
Neuroplasticity following traumatic brain injury: a study of GABAergic terminal loss and recovery in the cat dorsal lateral vestibular nucleus.
Topics: Animals; Brain; Brain Injuries; Cats; Female; gamma-Aminobutyric Acid; Immunoenzyme Techniques; Immu | 1991 |
[Nootropic agents in the complex treatment of patients with traumatic epilepsy].
Topics: Adult; Brain Injuries; Consciousness Disorders; Drug Therapy, Combination; Epilepsy, Post-Traumatic; | 1990 |
[The GABA-ergic system and brain edema].
Topics: Animals; Anti-Anxiety Agents; Benactyzine; Benzodiazepines; Benzodiazepinones; Brain Edema; Brain In | 1985 |
A nonglucocorticoid steroid analog of methylprednisolone duplicates its high-dose pharmacology in models of central nervous system trauma and neuronal membrane damage.
Topics: Adrenocorticotropic Hormone; Animals; Body Weight; Brain; Brain Injuries; Cells, Cultured; gamma-Ami | 1987 |
A systems approach to nerve regeneration.
Topics: Anaerobiosis; Animals; Brain; Brain Injuries; gamma-Aminobutyric Acid; Humans; Nerve Regeneration; N | 1987 |
[Gamma-aminobutyric acid concentrations in the plasma in unconscious patients with severe craniocerebral trauma or nontraumatic intracranial hemorrhage].
Topics: Adult; Aged; Brain Injuries; Cerebral Hemorrhage; Female; gamma-Aminobutyric Acid; Humans; Male; Mid | 1986 |
[Effects of 4-(o-benzylphenoxy)-N-methylbutylamine hydrochloride (MCI-2016, bifemelane hydrochloride) on spontaneous motor activity under different experimental conditions].
Topics: Animals; Benzhydryl Compounds; Brain Injuries; gamma-Aminobutyric Acid; Hypoxia, Brain; Male; Metham | 1985 |