gamma-aminobutyric acid has been researched along with Brain Inflammation in 39 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A retrospective analysis was performed of patients with autoimmune encephalitis who were treated with tryptophan IA in six neurological clinics between 2009 and 2013." | 7.81 | Tryptophan immunoadsorption for the treatment of autoimmune encephalitis. ( Baumgartner, A; Dohmen, C; Ehrlich, S; Fassbender, C; Haubitz, M; Hoffmann, F; Klingel, R; Köhler, W; Kraft, A; Neumann-Haefelin, T; Schmidt, S; Stich, O; Topka, H, 2015) |
| "A retrospective analysis was performed of patients with autoimmune encephalitis who were treated with tryptophan IA in six neurological clinics between 2009 and 2013." | 3.81 | Tryptophan immunoadsorption for the treatment of autoimmune encephalitis. ( Baumgartner, A; Dohmen, C; Ehrlich, S; Fassbender, C; Haubitz, M; Hoffmann, F; Klingel, R; Köhler, W; Kraft, A; Neumann-Haefelin, T; Schmidt, S; Stich, O; Topka, H, 2015) |
| "However 20-30% of patients with lacunar stroke worsen neurologically in hours or days after onset, reaching eventually an unexpectedly severe disability status." | 2.48 | Progressive lacunar stroke: review of mechanisms, prognostic features, and putative treatments. ( Del Bene, A; Inzitari, D; Lamassa, M; Palumbo, V; Piccardi, B; Saia, V, 2012) |
| "Anti-GABABR encephalitis is a limbic encephalitis with prominent, severe seizures, but patients can also present with rapidly progressive dementia." | 1.51 | The expanded clinical spectrum of anti-GABABR encephalitis and added value of KCTD16 autoantibodies. ( Bastiaansen, DAEM; Boukhrissi, S; de Bruijn, MAAM; de Graaff, E; Demmers, JAA; Hoogenraad, CC; Hulsenboom, ESP; Nagtzaam, MMP; Ramberger, M; Schreurs, MWJ; Sillevis Smitt, PAE; Titulaer, MJ; van Coevorden-Hameete, MH; Veldink, JH; Verschuuren, JJGM, 2019) |
| "Here, we evaluated brain inflammation, synaptic protein expression, and adult hippocampal neurogenesis in the epileptogenic (1 and 2 months of age) and tonic-clonic (3." | 1.42 | Alterations in Brain Inflammation, Synaptic Proteins, and Adult Hippocampal Neurogenesis during Epileptogenesis in Mice Lacking Synapsin2. ( Ali, I; Bahonjic, E; Bakochi, A; Chugh, D; Ekdahl, CT; Etholm, L, 2015) |
| "To learn whether epileptic seizures in Rasmussen encephalitis (RE) may be promoted by insufficient γ-aminobutyric acid (GABA) release." | 1.39 | Altered transporter-mediated neocortical GABA release in Rasmussen encephalitis. ( Feuerstein, TJ; Ramantani, G; Rassner, MP; van Velthoven-Wurster, V, 2013) |
| "Infantile Neuronal Ceroid Lipofuscinosis (INCL) results from mutations in the palmitoyl protein thioesterase (PPT1, CLN1) gene and is characterized by dramatic death of cortical neurons." | 1.33 | Mice with Ppt1Deltaex4 mutation replicate the INCL phenotype and show an inflammation-associated loss of interneurons. ( Fabritius, AL; Gentile, M; Jalanko, A; Kopra, O; Manninen, T; Minye, H; Peltonen, L; Rapola, J; Salonen, T; Vesa, J; von Schantz, C, 2005) |
| "Quisqualic acid was injected into the right nucleus basalis of rats." | 1.31 | Brain inflammatory reaction in an animal model of neuronal degeneration and its modulation by an anti-inflammatory drug: implication in Alzheimer's disease. ( Casamenti, F; Pepeu, G; Prosperi, C; Scali, C; Vannucchi, MG, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (15.38) | 18.7374 |
| 1990's | 2 (5.13) | 18.2507 |
| 2000's | 8 (20.51) | 29.6817 |
| 2010's | 13 (33.33) | 24.3611 |
| 2020's | 10 (25.64) | 2.80 |
| Authors | Studies |
|---|---|
| Kunchok, A | 1 |
| McKeon, A | 1 |
| Zekeridou, A | 1 |
| Flanagan, EP | 1 |
| Dubey, D | 1 |
| Lennon, VA | 1 |
| Klein, CJ | 1 |
| Mills, JR | 1 |
| Pittock, SJ | 1 |
| Deng, B | 1 |
| Cai, M | 1 |
| Qiu, Y | 1 |
| Liu, X | 1 |
| Yu, H | 1 |
| Zhang, X | 1 |
| Huang, H | 1 |
| Zhao, X | 1 |
| Yang, W | 1 |
| Dong, S | 1 |
| Jin, L | 1 |
| Chu, S | 1 |
| Chen, X | 1 |
| Uy, CE | 1 |
| Mayxay, M | 1 |
| Harrison, R | 1 |
| Al-Diwani, A | 1 |
| Jacobson, L | 1 |
| Rattanavong, S | 1 |
| Dubot-Pérès, A | 1 |
| Vongsouvath, M | 1 |
| Davong, V | 1 |
| Chansamouth, V | 1 |
| Phommasone, K | 1 |
| Waters, P | 1 |
| Irani, SR | 1 |
| Newton, PN | 1 |
| Chen, W | 1 |
| Wang, Y | 1 |
| Guo, X | 1 |
| Gao, L | 1 |
| Huang, Z | 1 |
| Lin, Y | 1 |
| Xue, Q | 1 |
| Liu, G | 1 |
| Zhang, Y | 1 |
| Su, Y | 1 |
| Noviello, CM | 1 |
| Kreye, J | 1 |
| Teng, J | 1 |
| Prüss, H | 1 |
| Hibbs, RE | 1 |
| Moss, TT | 1 |
| Stavem, K | 1 |
| Aandahl, A | 1 |
| Gløersen, AS | 1 |
| Grønberg, BH | 1 |
| Neumann, K | 1 |
| Vedeler, CA | 1 |
| Lundqvist, C | 1 |
| Shiwaku, H | 1 |
| Nakano, Y | 1 |
| Kato, M | 1 |
| Takahashi, H | 1 |
| Marchese, E | 1 |
| Valentini, M | 1 |
| Di Sante, G | 1 |
| Cesari, E | 1 |
| Adinolfi, A | 1 |
| Corvino, V | 1 |
| Ria, F | 1 |
| Sette, C | 1 |
| Geloso, MC | 1 |
| Park, GH | 1 |
| Noh, H | 1 |
| Shao, Z | 1 |
| Ni, P | 1 |
| Qin, Y | 1 |
| Liu, D | 1 |
| Beaudreault, CP | 1 |
| Park, JS | 1 |
| Abani, CP | 1 |
| Park, JM | 1 |
| Le, DT | 1 |
| Gonzalez, SZ | 1 |
| Guan, Y | 1 |
| Cohen, BM | 1 |
| McPhie, DL | 1 |
| Coyle, JT | 1 |
| Lanz, TA | 1 |
| Xi, HS | 1 |
| Yin, C | 1 |
| Huang, W | 1 |
| Kim, HY | 1 |
| Chung, S | 1 |
| Balcerac, A | 1 |
| Marois, C | 1 |
| Demeret, S | 1 |
| Le Guennec, L | 1 |
| Carreras, I | 1 |
| Aytan, N | 1 |
| Mellott, T | 1 |
| Choi, JK | 1 |
| Lehar, M | 1 |
| Crabtree, L | 1 |
| Leite-Morris, K | 1 |
| Jenkins, BG | 1 |
| Blusztajn, JK | 1 |
| Dedeoglu, A | 1 |
| Pilipenko, V | 1 |
| Narbute, K | 1 |
| Amara, I | 1 |
| Trovato, A | 1 |
| Scuto, M | 1 |
| Pupure, J | 1 |
| Jansone, B | 1 |
| Poikans, J | 1 |
| Bisenieks, E | 1 |
| Klusa, V | 1 |
| Calabrese, V | 1 |
| van Coevorden-Hameete, MH | 1 |
| de Bruijn, MAAM | 1 |
| de Graaff, E | 1 |
| Bastiaansen, DAEM | 1 |
| Schreurs, MWJ | 1 |
| Demmers, JAA | 1 |
| Ramberger, M | 1 |
| Hulsenboom, ESP | 1 |
| Nagtzaam, MMP | 1 |
| Boukhrissi, S | 1 |
| Veldink, JH | 1 |
| Verschuuren, JJGM | 1 |
| Hoogenraad, CC | 1 |
| Sillevis Smitt, PAE | 1 |
| Titulaer, MJ | 1 |
| Zhang, J | 1 |
| Li, J | 1 |
| Pang, BX | 1 |
| Wen, XM | 1 |
| Guo, L | 1 |
| Köhler, W | 1 |
| Ehrlich, S | 1 |
| Dohmen, C | 1 |
| Haubitz, M | 1 |
| Hoffmann, F | 1 |
| Schmidt, S | 1 |
| Klingel, R | 1 |
| Kraft, A | 1 |
| Neumann-Haefelin, T | 1 |
| Topka, H | 1 |
| Stich, O | 1 |
| Baumgartner, A | 1 |
| Fassbender, C | 1 |
| Dal-Pizzol, F | 1 |
| Tomasi, CD | 1 |
| Ritter, C | 1 |
| Saad, MA | 1 |
| Abdelsalam, RM | 1 |
| Kenawy, SA | 1 |
| Attia, AS | 1 |
| Chugh, D | 1 |
| Ali, I | 1 |
| Bakochi, A | 1 |
| Bahonjic, E | 1 |
| Etholm, L | 1 |
| Ekdahl, CT | 1 |
| Hui, AT | 1 |
| Lam, YO | 1 |
| Chan, CK | 1 |
| Cheung, KY | 1 |
| Fung, BH | 1 |
| Ng, PW | 1 |
| Bjurstöm, H | 1 |
| Wang, J | 2 |
| Ericsson, I | 1 |
| Bengtsson, M | 1 |
| Liu, Y | 1 |
| Kumar-Mendu, S | 1 |
| Issazadeh-Navikas, S | 1 |
| Birnir, B | 1 |
| Korff, CM | 1 |
| Parvex, P | 1 |
| Cimasoni, L | 1 |
| Wilhelm-Bals, A | 1 |
| Hampe, CS | 1 |
| Schwitzgebel, VM | 1 |
| Michel, M | 1 |
| Siegrist, CA | 1 |
| Lalive, PH | 1 |
| Seeck, M | 1 |
| Del Bene, A | 1 |
| Palumbo, V | 1 |
| Lamassa, M | 1 |
| Saia, V | 1 |
| Piccardi, B | 1 |
| Inzitari, D | 1 |
| Kern, JK | 1 |
| Geier, DA | 1 |
| Audhya, T | 1 |
| King, PG | 1 |
| Sykes, LK | 1 |
| Geier, MR | 1 |
| Rassner, MP | 1 |
| van Velthoven-Wurster, V | 1 |
| Ramantani, G | 1 |
| Feuerstein, TJ | 1 |
| Jalanko, A | 1 |
| Vesa, J | 1 |
| Manninen, T | 1 |
| von Schantz, C | 1 |
| Minye, H | 1 |
| Fabritius, AL | 1 |
| Salonen, T | 1 |
| Rapola, J | 1 |
| Gentile, M | 1 |
| Kopra, O | 1 |
| Peltonen, L | 1 |
| Hellstrom, IC | 1 |
| Danik, M | 1 |
| Luheshi, GN | 1 |
| Williams, S | 1 |
| Gavilán, MP | 1 |
| Revilla, E | 1 |
| Pintado, C | 1 |
| Castaño, A | 1 |
| Vizuete, ML | 1 |
| Moreno-González, I | 1 |
| Baglietto-Vargas, D | 1 |
| Sánchez-Varo, R | 1 |
| Vitorica, J | 1 |
| Gutiérrez, A | 1 |
| Ruano, D | 1 |
| Franklin, SL | 1 |
| Love, S | 1 |
| Greene, JR | 1 |
| Betmouni, S | 1 |
| Elizan, TS | 1 |
| Maker, H | 1 |
| Yahr, MD | 1 |
| Manyam, NV | 1 |
| Katz, L | 1 |
| Hare, TA | 1 |
| Gerber, JC | 1 |
| Grossman, MH | 1 |
| Ifergane, G | 1 |
| Masalha, R | 1 |
| Zigulinski, R | 1 |
| Merkin, L | 1 |
| Wirguin, I | 1 |
| Herishanu, YO | 1 |
| Gibbs, JW | 1 |
| Morton, LD | 1 |
| Amaker, B | 1 |
| Ward, JD | 1 |
| Holloway, KL | 1 |
| Coulter, DA | 1 |
| Scali, C | 1 |
| Prosperi, C | 1 |
| Vannucchi, MG | 1 |
| Pepeu, G | 1 |
| Casamenti, F | 1 |
| Engelborghs, S | 1 |
| D'Hooge, R | 1 |
| De Deyn, PP | 1 |
| Castellanos, M | 1 |
| Castillo, J | 1 |
| García, MM | 1 |
| Leira, R | 1 |
| Serena, J | 1 |
| Chamorro, A | 1 |
| Dávalos, A | 1 |
| Buryakova, AV | 1 |
| Sytinsky, IA | 1 |
| Lukashevich, LP | 1 |
| Samosiuk, IZ | 1 |
| Filonchik, AA | 1 |
| Prasad, GV | 1 |
| Rajendra, W | 1 |
| Indira, K | 1 |
| Neeley, SP | 1 |
| Cross, AJ | 1 |
| Crow, TJ | 1 |
| Johnson, JA | 1 |
| Taylor, GR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Vigabatrin in Refractory Autoimmune Encephalitis Patients - A Pilot Study[NCT03003143] | 0 participants (Actual) | Interventional | 2016-11-30 | Withdrawn | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for gamma-aminobutyric acid and Brain Inflammation
| Article | Year |
|---|---|
Septic encephalopathy: does inflammation drive the brain crazy?
Topics: Amines; Brain; Central Nervous System; Cytokines; Encephalitis; gamma-Aminobutyric Acid; Humans; Sep | 2014 |
Encephalitis associated with glutamic acid decarboxylase autoantibodies in a child: a treatable condition?
Topics: Antibodies, Monoclonal, Murine-Derived; Anticonvulsants; Antirheumatic Agents; Autoantibodies; Child | 2011 |
Progressive lacunar stroke: review of mechanisms, prognostic features, and putative treatments.
Topics: Anticoagulants; Blood Pressure; Brain Edema; Cerebral Infarction; Disease Progression; Encephalitis; | 2012 |
Evidence of parallels between mercury intoxication and the brain pathology in autism.
Topics: Amyloid beta-Protein Precursor; Animals; Autistic Disorder; Brain; Calcium; Cerebellum; Cytokines; E | 2012 |
Pathophysiology of epilepsy.
Topics: Adult; Animals; Anticonvulsants; Autoimmune Diseases; Calcium; Catecholamines; Cell Movement; Child; | 2000 |
34 other studies available for gamma-aminobutyric acid and Brain Inflammation
| Article | Year |
|---|---|
Autoimmune/Paraneoplastic Encephalitis Antibody Biomarkers: Frequency, Age, and Sex Associations.
Topics: Adult; Aged; Autoantibodies; Biomarkers; Child; Encephalitis; Female; gamma-Aminobutyric Acid; Human | 2022 |
MRI Characteristics of Autoimmune Encephalitis With Autoantibodies to GABAA Receptor: A Case Series.
Topics: Adolescent; Adult; Aged; Autoantibodies; Encephalitis; Female; gamma-Aminobutyric Acid; Hashimoto Di | 2022 |
Detection and significance of neuronal autoantibodies in patients with meningoencephalitis in Vientiane, Lao PDR.
Topics: Autoantibodies; Contactins; Encephalitis; gamma-Aminobutyric Acid; Hashimoto Disease; Humans; Laos; | 2022 |
A Prognostic Analysis of the Outcomes in Patients With Anti-γ-Aminobutyric Acid B Receptor Encephalitis.
Topics: Aged; Antibodies; Biomarkers, Tumor; Cohort Studies; Encephalitis; gamma-Aminobutyric Acid; Humans; | 2022 |
Structural mechanisms of GABA
Topics: Autoantibodies; Cryoelectron Microscopy; Encephalitis; gamma-Aminobutyric Acid; Hashimoto Disease; H | 2022 |
Case Report: Limbic encephalitis following treatment with durvalumab for small-cell lung cancer.
Topics: Aged; Antibodies, Monoclonal; Autoantibodies; Diabetes Mellitus; Encephalitis; gamma-Aminobutyric Ac | 2023 |
Detection of autoantibodies against GABA
Topics: Autoantibodies; Encephalitis; gamma-Aminobutyric Acid; Humans; Receptors, N-Methyl-D-Aspartate; Schi | 2020 |
Alternative splicing of neurexins 1-3 is modulated by neuroinflammation in the prefrontal cortex of a murine model of multiple sclerosis.
Topics: Alternative Splicing; Animals; Calcium-Binding Proteins; Cognitive Dysfunction; Encephalitis; Enceph | 2021 |
Activated microglia cause metabolic disruptions in developmental cortical interneurons that persist in interneurons from individuals with schizophrenia.
Topics: Adult; Cerebral Cortex; Coculture Techniques; Encephalitis; gamma-Aminobutyric Acid; Gene Expression | 2020 |
GABA-A encephalitis: status epilepticus and asymmetrical temporal lesions are not always herpes simplex-1 encephalitis.
Topics: Encephalitis; Encephalitis, Herpes Simplex; gamma-Aminobutyric Acid; Herpes Simplex; Humans; Status | 2023 |
Anxiety, neuroinflammation, cholinergic and GABAergic abnormalities are early markers of Gulf War illness in a mouse model of the disease.
Topics: Acetylcholine; Animals; Anxiety; Astrocytes; Brain; DEET; Disease Models, Animal; Encephalitis; Fema | 2018 |
GABA-containing compound gammapyrone protects against brain impairments in Alzheimer's disease model male rats and prevents mitochondrial dysfunction in cell culture.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Astrocytes; Brain; Cells, Cultured; Disease Models | 2019 |
The expanded clinical spectrum of anti-GABABR encephalitis and added value of KCTD16 autoantibodies.
Topics: Adult; Aged; Aged, 80 and over; Autoantibodies; Encephalitis; Female; gamma-Aminobutyric Acid; Human | 2019 |
[Patients with anti-GABA (B) receptor encephalitis: 8 cases report].
Topics: Autoantibodies; Encephalitis; gamma-Aminobutyric Acid; Humans; Lung Neoplasms; Receptors, GABA-B; Re | 2019 |
Tryptophan immunoadsorption for the treatment of autoimmune encephalitis.
Topics: Adult; Aged; Anti-N-Methyl-D-Aspartate Receptor Encephalitis; Autoantibodies; Cytoskeletal Proteins; | 2015 |
Ischemic preconditioning and postconditioning alleviates hippocampal tissue damage through abrogation of apoptosis modulated by oxidative stress and inflammation during transient global cerebral ischemia-reperfusion in rats.
Topics: Animals; Apoptosis; Biomarkers; Brain Ischemia; Encephalitis; gamma-Aminobutyric Acid; Glutamic Acid | 2015 |
Alterations in Brain Inflammation, Synaptic Proteins, and Adult Hippocampal Neurogenesis during Epileptogenesis in Mice Lacking Synapsin2.
Topics: Animals; Carrier Proteins; Cell Adhesion Molecules, Neuronal; Cerebral Cortex; Chemokines; Cytokines | 2015 |
A case of refractory seizure with cognitive impairment due to anti-GABA encephalitis.
Topics: Cognitive Dysfunction; Encephalitis; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Seizures | 2016 |
GABA, a natural immunomodulator of T lymphocytes.
Topics: Animals; Cell Line, Transformed; Cell Proliferation; Dose-Response Relationship, Drug; Encephalitis; | 2008 |
Altered transporter-mediated neocortical GABA release in Rasmussen encephalitis.
Topics: Encephalitis; gamma-Aminobutyric Acid; Humans; Neocortex; Sodium-Calcium Exchanger; Synaptosomes; Ve | 2013 |
Mice with Ppt1Deltaex4 mutation replicate the INCL phenotype and show an inflammation-associated loss of interneurons.
Topics: Animals; Animals, Newborn; Blindness, Cortical; Cell Death; Cerebral Cortex; Disease Models, Animal; | 2005 |
Chronic LPS exposure produces changes in intrinsic membrane properties and a sustained IL-beta-dependent increase in GABAergic inhibition in hippocampal CA1 pyramidal neurons.
Topics: Action Potentials; Animals; Encephalitis; gamma-Aminobutyric Acid; Hippocampus; Interleukin-1; Inter | 2005 |
Molecular and cellular characterization of the age-related neuroinflammatory processes occurring in normal rat hippocampus: potential relation with the loss of somatostatin GABAergic neurons.
Topics: Aging; Animals; Cell Count; Cell Death; Down-Regulation; Encephalitis; gamma-Aminobutyric Acid; Gene | 2007 |
Loss of Perineuronal Net in ME7 Prion Disease.
Topics: Animals; Disease Models, Animal; Disease Progression; Encephalitis; Extracellular Matrix; Female; ga | 2008 |
Neurotransmitter synthesizing enzymes in experimental viral encephalitis.
Topics: Acetylcholine; Animals; Caudate Nucleus; Choline O-Acetyltransferase; Dopamine; Encephalitis; Female | 1983 |
Levels of gamma-aminobutyric acid in cerebrospinal fluid in various neurologic disorders.
Topics: Brain Chemistry; Cerebellar Diseases; Creatine Kinase; Dementia; Diet; Encephalitis; Epilepsy; gamma | 1980 |
Acute encephalopathy associated with vigabatrin monotherapy in patients with mild renal failure.
Topics: Acute Disease; Adult; Aged; Anticonvulsants; Electroencephalography; Encephalitis; Epilepsy, General | 1998 |
Physiological analysis of Rasmussen's encephalitis: patch clamp recordings of altered inhibitory neurotransmitter function in resected frontal cortical tissue.
Topics: Cell Size; Cells, Cultured; Cerebral Cortex; Child; Chronic Disease; Clonazepam; Dose-Response Relat | 1998 |
Brain inflammatory reaction in an animal model of neuronal degeneration and its modulation by an anti-inflammatory drug: implication in Alzheimer's disease.
Topics: Acetylcholine; Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Choline O-Acetyl | 2000 |
Inflammation-mediated damage in progressing lacunar infarctions: a potential therapeutic target.
Topics: Aged; Biomarkers; Brain Infarction; Disease Progression; Encephalitis; Female; gamma-Aminobutyric Ac | 2002 |
Amino acid composition of cerebrospinal fluid in actue neuroinfections in children.
Topics: Acute Disease; Adolescent; Adrenocorticotropic Hormone; Amino Acids; Child; Child, Preschool; Chlora | 1975 |
[Use of certain preparations of gamma-aminobutyric acid in diseases of the nervous system].
Topics: Adolescent; Adult; Aged; Aminobutyrates; Brain Injuries; Cerebrovascular Disorders; Child; Drug Eval | 1975 |
Brain ammonia metabolism in hexachlorophene-induced encephalopathy.
Topics: Ammonia; Animals; Brain; Encephalitis; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutamine | 1987 |
Herpes simplex virus encephalitis. Neuroanatomical and neurochemical selectivity.
Topics: Acetylcholine; Animals; Antigens, Viral; Brain Chemistry; Dopamine; Encephalitis; gamma-Aminobutyric | 1985 |