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gamma-aminobutyric acid and Brain Infarction

gamma-aminobutyric acid has been researched along with Brain Infarction in 12 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Brain Infarction: Tissue NECROSIS in any area of the brain, including the CEREBRAL HEMISPHERES, the CEREBELLUM, and the BRAIN STEM. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by HYPOXIA and HYPOGLYCEMIA in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis.

Research Excerpts

ExcerptRelevanceReference
"Gabapentin pretreatment (200  mg/kg, intravenously) reduced the infarct volume by 23% after transient focal ischemia in mice."1.37Gabapentin reduces infarct volume but does not suppress peri-infarct depolarizations. ( Ayata, C; Eikermann-Haerter, K; Hoffmann, U; Lee, JH; Qin, T, 2011)
"After global cerebral ischemia, delayed cell death is observed in the thalamic reticular nucleus but the mechanisms involved are not well described."1.35Endonuclease G expression in thalamic reticular nucleus after global cerebral ischemia. ( Diemer, NH; Nielsen, M; Zimmer, J, 2008)
"Nonconvulsive seizures (NCSs) after traumatic and ischemic brain injury are often refractory to antiepileptic drug therapy and are associated with a decline in patient outcome."1.32Antiepileptic drug treatment of nonconvulsive seizures induced by experimental focal brain ischemia. ( Hartings, JA; Lu, XM; Moreton, JE; Tortella, FC; Williams, AJ, 2004)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (50.00)29.6817
2010's5 (41.67)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Khirug, S1
Soni, S1
Saez Garcia, M1
Tessier, M1
Zhou, L1
Kulesskaya, N1
Rauvala, H1
Lindholm, D1
Ludwig, A1
Molinari, F1
Rivera, C1
Ramírez-Sánchez, J1
Pires, ENS1
Meneghetti, A1
Hansel, G1
Nuñez-Figueredo, Y1
Pardo-Andreu, GL1
Ochoa-Rodríguez, E1
Verdecia-Reyes, Y1
Delgado-Hernández, R1
Salbego, C1
Souza, DO1
Xu, Q1
Yang, JW1
Cao, Y1
Zhang, LW1
Zeng, XH1
Li, F1
Du, SQ1
Wang, LP1
Liu, CZ1
Nielsen, M1
Zimmer, J1
Diemer, NH1
Li, C1
Yan, Z1
Yang, J1
Chen, H1
Li, H1
Jiang, Y1
Zhang, Z1
Hoffmann, U1
Lee, JH1
Qin, T1
Eikermann-Haerter, K1
Ayata, C1
Fan, YY1
Zhang, XN1
He, P1
Shen, Z1
Shen, Y1
Wang, XF1
Hu, WW1
Chen, Z1
Williams, AJ1
Tortella, FC1
Lu, XM1
Moreton, JE1
Hartings, JA1
Frahm, C1
Siegel, G1
Grass, S1
Witte, OW1
Hwang, IK1
Yoo, KY1
Kim, DH1
Lee, BH1
Kwon, YG1
Won, MH1
Serena, J2
Leira, R2
Castillo, J2
Pumar, JM1
Castellanos, M2
Dávalos, A2
García, MM1
Chamorro, A1

Trials

1 trial available for gamma-aminobutyric acid and Brain Infarction

ArticleYear
Neurological deterioration in acute lacunar infarctions: the role of excitatory and inhibitory neurotransmitters.
    Stroke, 2001, Volume: 32, Issue:5

    Topics: Acute Disease; Aged; Brain Infarction; Disease Progression; Female; gamma-Aminobutyric Acid; Glutami

2001

Other Studies

11 other studies available for gamma-aminobutyric acid and Brain Infarction

ArticleYear
Protective Role of Low Ethanol Administration Following Ischemic Stroke via Recovery of KCC2 and p75
    Molecular neurobiology, 2021, Volume: 58, Issue:3

    Topics: Animals; Apoptosis; Biological Transport; Biomarkers; Brain Infarction; Cell Survival; Chlorides; Di

2021
JM-20 Treatment After MCAO Reduced Astrocyte Reactivity and Neuronal Death on Peri-infarct Regions of the Rat Brain.
    Molecular neurobiology, 2019, Volume: 56, Issue:1

    Topics: Animals; Astrocytes; Benzodiazepines; Brain; Brain Infarction; CA3 Region, Hippocampal; Cell Death;

2019
Acupuncture improves locomotor function by enhancing GABA receptor expression in transient focal cerebral ischemia rats.
    Neuroscience letters, 2015, Feb-19, Volume: 588

    Topics: Acupuncture Therapy; Animals; beta-Endorphin; Brain Infarction; Cerebral Cortex; Corpus Striatum; ga

2015
Endonuclease G expression in thalamic reticular nucleus after global cerebral ischemia.
    Experimental brain research, 2008, Volume: 190, Issue:1

    Topics: Active Transport, Cell Nucleus; Animals; Apoptosis; Astrocytes; Biomarkers; Brain Infarction; Brain

2008
Neuroprotective effects of resveratrol on ischemic injury mediated by modulating the release of neurotransmitter and neuromodulator in rats.
    Neurochemistry international, 2010, Volume: 56, Issue:3

    Topics: Animals; Antioxidants; Brain; Brain Infarction; Disease Models, Animal; Ethanolamines; Excitatory Po

2010
Gabapentin reduces infarct volume but does not suppress peri-infarct depolarizations.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2011, Volume: 31, Issue:7

    Topics: Amines; Animals; Anticonvulsants; Brain; Brain Infarction; Brain Ischemia; Cortical Spreading Depres

2011
Transient lack of glucose but not O2 is involved in ischemic postconditioning-induced neuroprotection.
    CNS neuroscience & therapeutics, 2013, Volume: 19, Issue:1

    Topics: Animals; Brain Infarction; Chromatography, High Pressure Liquid; Disease Models, Animal; gamma-Amino

2013
Antiepileptic drug treatment of nonconvulsive seizures induced by experimental focal brain ischemia.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:1

    Topics: Amines; Animals; Anticonvulsants; Brain Infarction; Brain Injuries; Brain Ischemia; Cyclohexanecarbo

2004
Stable expression of the vesicular GABA transporter following photothrombotic infarct in rat brain.
    Neuroscience, 2006, Jul-07, Volume: 140, Issue:3

    Topics: Animals; Brain; Brain Infarction; Cerebral Cortex; Disease Models, Animal; Exocytosis; gamma-Aminobu

2006
Time course of changes in pyridoxal 5'-phosphate (vitamin B6 active form) and its neuroprotection in experimental ischemic damage.
    Experimental neurology, 2007, Volume: 206, Issue:1

    Topics: 4-Aminobutyrate Transaminase; Aldehyde Oxidoreductases; Animals; Astrocytes; Brain Infarction; Brain

2007
Inflammation-mediated damage in progressing lacunar infarctions: a potential therapeutic target.
    Stroke, 2002, Volume: 33, Issue:4

    Topics: Aged; Biomarkers; Brain Infarction; Disease Progression; Encephalitis; Female; gamma-Aminobutyric Ac

2002