gamma-aminobutyric acid has been researched along with Brain Edema in 30 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To observe the changes of glutamates (Glu) and gamma-aminobutyric acid (GABA) contents in brain tissue of infectious brain edema, and effects of baicalin on them in rats." | 7.70 | [Changes of glutamate and gamma-aminobutyric acid contents in brain tissue of brain edema and effects of baicalin on them in rats]. ( Yang, Y; Yin, F; Yu, P, 2000) |
| "The high performance liquid chromatography (HPLC) was used to determine the Glu and GABA contents in homogenized brain tissue after baicalin was injected intraperitoneally on infectious brain edema induced by pertussis bacilli in rats." | 7.70 | [Changes of glutamate and gamma-aminobutyric acid contents in brain tissue of brain edema and effects of baicalin on them in rats]. ( Yang, Y; Yin, F; Yu, P, 2000) |
| "Baicalin has a protective effect against the pertussis bacilli-induced brain edema in rats, and protective effect was correlated to the increased content of GABA in the brain tissue in rats." | 7.70 | [Changes of glutamate and gamma-aminobutyric acid contents in brain tissue of brain edema and effects of baicalin on them in rats]. ( Yang, Y; Yin, F; Yu, P, 2000) |
| "Baicalin has a protective effect against the pertussis bacilli-induced brain edema in rats, and protective effect was correlated to the increased content of GABA in the brain tissue in rats." | 5.31 | [Changes of glutamate and gamma-aminobutyric acid contents in brain tissue of brain edema and effects of baicalin on them in rats]. ( Yang, Y; Yin, F; Yu, P, 2000) |
| "To observe the changes of glutamates (Glu) and gamma-aminobutyric acid (GABA) contents in brain tissue of infectious brain edema, and effects of baicalin on them in rats." | 3.70 | [Changes of glutamate and gamma-aminobutyric acid contents in brain tissue of brain edema and effects of baicalin on them in rats]. ( Yang, Y; Yin, F; Yu, P, 2000) |
| "The high performance liquid chromatography (HPLC) was used to determine the Glu and GABA contents in homogenized brain tissue after baicalin was injected intraperitoneally on infectious brain edema induced by pertussis bacilli in rats." | 3.70 | [Changes of glutamate and gamma-aminobutyric acid contents in brain tissue of brain edema and effects of baicalin on them in rats]. ( Yang, Y; Yin, F; Yu, P, 2000) |
| "Baicalin has a protective effect against the pertussis bacilli-induced brain edema in rats, and protective effect was correlated to the increased content of GABA in the brain tissue in rats." | 3.70 | [Changes of glutamate and gamma-aminobutyric acid contents in brain tissue of brain edema and effects of baicalin on them in rats]. ( Yang, Y; Yin, F; Yu, P, 2000) |
| "Hyperammonemia is necessary for development of the cerebral complications to liver disease including hepatic encephalopathy and cerebral edema but the mechanisms are unclear." | 2.50 | Cerebral effects of ammonia in liver disease: current hypotheses. ( Ott, P; Vilstrup, H, 2014) |
| "Hepatic encephalopathy is a medical phenomenon that is described as a neuropsychiatric manifestation of chronic or acute liver disease that is characterized by psychomotor, intellectual and cognitive abnormalities with emotional/affective and behavioral disturbances." | 2.49 | Current pathogenetic aspects of hepatic encephalopathy and noncirrhotic hyperammonemic encephalopathy. ( Cichoż-Lach, H; Michalak, A, 2013) |
| "Acute liver failure (ALF) or fulminant hepatic failure represents a serious life-threatening condition." | 2.48 | GABAergic neurosteroids: the "endogenous benzodiazepines" of acute liver failure. ( Ahboucha, S; Baker, G; Gamrani, H, 2012) |
| "However 20-30% of patients with lacunar stroke worsen neurologically in hours or days after onset, reaching eventually an unexpectedly severe disability status." | 2.48 | Progressive lacunar stroke: review of mechanisms, prognostic features, and putative treatments. ( Del Bene, A; Inzitari, D; Lamassa, M; Palumbo, V; Piccardi, B; Saia, V, 2012) |
| "Patients with high-altitude cerebral edema have similar splenial-predominant magnetic resonance imaging abnormalities that accompany these same neurological symptoms." | 1.33 | Pregabalin-withdrawal encephalopathy and splenial edema: a link to high-altitude illness? ( Buchbinder, BR; Oaklander, AL, 2005) |
| "Baicalin has a protective effect against the pertussis bacilli-induced brain edema in rats, and protective effect was correlated to the increased content of GABA in the brain tissue in rats." | 1.31 | [Changes of glutamate and gamma-aminobutyric acid contents in brain tissue of brain edema and effects of baicalin on them in rats]. ( Yang, Y; Yin, F; Yu, P, 2000) |
| "Taurine release was most affected, exhibiting a greater than 9-fold increase during the hyposmotic stimulus." | 1.30 | Hyposmotically induced amino acid release from the rat cerebral cortex: role of phospholipases and protein kinases. ( Estevez, AY; O'Regan, MH; Phillis, JW; Song, D, 1999) |
| " In an attempt to image these changes in vivo, we performed high-field MRI on seven treated and four control dogs at baseline and after 15 weeks of dosing with vigabatrin (300 mg/kg/d)." | 1.29 | MRI monitoring of vigabatrin-induced intramyelinic edema in dogs. ( Arezzo, JC; Gibson, JP; Heydorn, WE; Kastin, SJ; McBride, RG; Schroeder, CE; Sussman, NM; Weiss, KL; Yarrington, JT, 1994) |
| " There was no abnormal locomotor activity in the L-CPA rats treated with MK-801 except for the first 4 hr following dosing when animals were severely sedated." | 1.29 | L-2-chloropropionic acid-induced neurotoxicity is prevented by MK-801: possible role of NMDA receptors in the neuropathology. ( Gyte, A; Lock, EA; Simpson, MG; Widdowson, PS; Wyatt, I, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (26.67) | 18.7374 |
| 1990's | 11 (36.67) | 18.2507 |
| 2000's | 4 (13.33) | 29.6817 |
| 2010's | 7 (23.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ott, P | 1 |
| Vilstrup, H | 1 |
| Dahlberg, D | 1 |
| Mariussen, E | 1 |
| Goverud, IL | 1 |
| Tønjum, T | 1 |
| Mæhlen, J | 1 |
| Antal, EA | 1 |
| Hassel, B | 1 |
| Zhang, L | 1 |
| Jin, J | 1 |
| Yao, J | 1 |
| Yue, Z | 1 |
| Wei, Y | 1 |
| Yang, W | 1 |
| Fu, S | 1 |
| Li, W | 1 |
| Brady, JD | 1 |
| Mohr, C | 1 |
| Rossi, DJ | 1 |
| Ahboucha, S | 1 |
| Gamrani, H | 1 |
| Baker, G | 1 |
| Del Bene, A | 1 |
| Palumbo, V | 1 |
| Lamassa, M | 1 |
| Saia, V | 1 |
| Piccardi, B | 1 |
| Inzitari, D | 1 |
| Cichoż-Lach, H | 1 |
| Michalak, A | 1 |
| Zunker, P | 1 |
| Golombeck, K | 1 |
| Brossmann, J | 1 |
| Georgiadis, D | 1 |
| Deuschl, G | 1 |
| Oaklander, AL | 1 |
| Buchbinder, BR | 1 |
| Kiewert, C | 1 |
| Kumar, V | 1 |
| Hildmann, O | 1 |
| Rueda, M | 1 |
| Hartmann, J | 1 |
| Naik, RS | 1 |
| Klein, J | 1 |
| Schenker, S | 1 |
| Hoyumpa, AM | 1 |
| Gardner-Medwin, AR | 1 |
| Mutch, WA | 1 |
| Jellinger, K | 1 |
| Riederer, P | 1 |
| Mrsulja, BB | 1 |
| Djuricić, BM | 1 |
| Cvejić, V | 1 |
| Mrsulja, BJ | 1 |
| Abe, K | 2 |
| Spatz, M | 2 |
| Klatzo, I | 2 |
| Abe, T | 1 |
| Cocito, L | 1 |
| Maffini, M | 1 |
| Mousseau, DD | 1 |
| Butterworth, RF | 1 |
| Weiss, KL | 1 |
| Schroeder, CE | 1 |
| Kastin, SJ | 1 |
| Gibson, JP | 2 |
| Yarrington, JT | 2 |
| Heydorn, WE | 2 |
| McBride, RG | 1 |
| Sussman, NM | 2 |
| Arezzo, JC | 1 |
| Westergren, I | 1 |
| Nyström, B | 1 |
| Hamberger, A | 1 |
| Johansson, BB | 1 |
| Peyster, RG | 1 |
| Hershey, BL | 1 |
| Meyerson, LR | 1 |
| de Curtis, M | 1 |
| Arcelli, P | 1 |
| De Biasi, S | 1 |
| Spreafico, R | 1 |
| Avanzini, G | 1 |
| Widdowson, PS | 1 |
| Wyatt, I | 1 |
| Gyte, A | 1 |
| Simpson, MG | 1 |
| Lock, EA | 1 |
| Tan, WK | 1 |
| Williams, CE | 1 |
| During, MJ | 1 |
| Mallard, CE | 1 |
| Gunning, MI | 1 |
| Gunn, AJ | 1 |
| Gluckman, PD | 1 |
| Haugstad, TS | 1 |
| Karlsen, HE | 1 |
| Krajtci, P | 1 |
| Due-Tønnessen, B | 1 |
| Larsen, M | 1 |
| Sandberg, C | 1 |
| Sand, O | 1 |
| Brandtzaeg, P | 1 |
| Langmoen, IA | 1 |
| Phillis, JW | 2 |
| Song, D | 2 |
| O'Regan, MH | 2 |
| Estevez, AY | 1 |
| Yin, F | 1 |
| Yang, Y | 1 |
| Yu, P | 1 |
| Arrigoni, E | 1 |
| Averet, N | 1 |
| Loiseau, H | 1 |
| Cohadon, F | 1 |
| Iasnetsov, VS | 1 |
| Novikov, VE | 1 |
| Buniatian, HCh | 1 |
| Dallakian, BCh | 1 |
6 reviews available for gamma-aminobutyric acid and Brain Edema
| Article | Year |
|---|---|
Cerebral effects of ammonia in liver disease: current hypotheses.
Topics: Ammonia; Animals; Astrocytes; Blood-Brain Barrier; Brain Edema; Diffusion; Energy Metabolism; gamma- | 2014 |
GABAergic neurosteroids: the "endogenous benzodiazepines" of acute liver failure.
Topics: Benzodiazepines; Brain Edema; gamma-Aminobutyric Acid; Humans; Intracranial Pressure; Liver Failure, | 2012 |
Progressive lacunar stroke: review of mechanisms, prognostic features, and putative treatments.
Topics: Anticoagulants; Blood Pressure; Brain Edema; Cerebral Infarction; Disease Progression; Encephalitis; | 2012 |
Current pathogenetic aspects of hepatic encephalopathy and noncirrhotic hyperammonemic encephalopathy.
Topics: Ammonia; Animals; Blood-Brain Barrier; Brain; Brain Edema; gamma-Aminobutyric Acid; Hepatic Encephal | 2013 |
Pathophysiology of hepatic encephalopathy.
Topics: Amino Acids; Ammonia; Animals; Blood-Brain Barrier; Brain; Brain Edema; Evoked Potentials, Visual; F | 1984 |
Current theories on the pathogenesis of hepatic encephalopathy.
Topics: Ammonia; Animals; Brain; Brain Edema; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hepatic | 1994 |
1 trial available for gamma-aminobutyric acid and Brain Edema
| Article | Year |
|---|---|
Post-partum cerebral angiopathy: repetitive TCD, MRI, MRA, and EEG examinations.
Topics: Acetates; Adult; Amines; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Aspirin; Brain Ed | 2002 |
23 other studies available for gamma-aminobutyric acid and Brain Edema
| Article | Year |
|---|---|
Staphylococcal α-hemolysin is neurotoxic and causes lysis of brain cells in vivo and in vitro.
Topics: Animals; Astrocytes; Bacterial Toxins; Brain; Brain Edema; Cell Death; Cells, Cultured; gamma-Aminob | 2015 |
Effects of Propofol on Excitatory and Inhibitory Amino Acid Neurotransmitter Balance in Rats with Neurogenic Pulmonary Edema Induced by Subarachnoid Hemorrhage.
Topics: Animals; Brain; Brain Edema; Disease Models, Animal; Excitatory Amino Acids; gamma-Aminobutyric Acid | 2016 |
Vesicular GABA release delays the onset of the Purkinje cell terminal depolarization without affecting tissue swelling in cerebellar slices during simulated ischemia.
Topics: Animals; Brain Edema; Brain Ischemia; Cerebellum; Excitatory Postsynaptic Potentials; GABA-A Recepto | 2010 |
Pregabalin-withdrawal encephalopathy and splenial edema: a link to high-altitude illness?
Topics: Aged; Aged, 80 and over; Altitude Sickness; Anticonvulsants; Brain Edema; Female; gamma-Aminobutyric | 2005 |
Role of GABAergic antagonism in the neuroprotective effects of bilobalide.
Topics: Animals; Area Under Curve; Bicuculline; Brain Edema; Bridged Bicyclo Compounds, Heterocyclic; Cholin | 2007 |
Experiments on spreading depression in relation to migraine and neurosurgery.
Topics: Animals; Brain Edema; Cerebral Cortex; Cortical Spreading Depression; Electroencephalography; gamma- | 1984 |
[Central neurotransmitters in cerebral ischemia and stroke].
Topics: Animals; Blood-Brain Barrier; Brain Edema; Brain Ischemia; Cerebral Infarction; Cerebrovascular Diso | 1983 |
Biochemistry of experimental ischemic brain edema.
Topics: Adenine Nucleotides; Animals; Basal Ganglia; Biogenic Amines; Brain; Brain Edema; Brain Ischemia; Cy | 1980 |
Effect of endogenous central nervous system depressants in ischemic cerebral edema of gerbils.
Topics: 4-Butyrolactone; Animals; Blood-Brain Barrier; Brain Edema; Brain Ischemia; Furans; gamma-Aminobutyr | 1980 |
Vigabatrin edema.
Topics: Anticonvulsants; Brain; Brain Edema; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Vi | 1995 |
MRI monitoring of vigabatrin-induced intramyelinic edema in dogs.
Topics: 4-Aminobutyrate Transaminase; Animals; Brain Edema; Dogs; gamma-Aminobutyric Acid; Hippocampus; Hypo | 1994 |
Amino acids in extracellular fluid in vasogenic brain edema.
Topics: Amino Acids; Animals; Blood-Brain Barrier; Brain Edema; Dose-Response Relationship, Drug; Ethanolami | 1994 |
Use of ex vivo magnetic resonance imaging to detect onset of vigabatrin-induced intramyelinic edema in canine brain.
Topics: Animals; Anticonvulsants; Brain; Brain Edema; Dogs; Dose-Response Relationship, Drug; Female; gamma- | 1995 |
Ultrastructural features of the isolated guinea-pig brain maintained in vitro by arterial perfusion.
Topics: Animals; Astrocytes; Brain; Brain Edema; Cerebral Arteries; gamma-Aminobutyric Acid; Guinea Pigs; Im | 1994 |
L-2-chloropropionic acid-induced neurotoxicity is prevented by MK-801: possible role of NMDA receptors in the neuropathology.
Topics: Administration, Oral; Animals; Aspartic Acid; Autoradiography; Brain Edema; Cerebellum; Dizocilpine | 1996 |
Accumulation of cytotoxins during the development of seizures and edema after hypoxic-ischemic injury in late gestation fetal sheep.
Topics: Animals; Aspartic Acid; Brain Edema; Brain Ischemia; Cytotoxins; Electroencephalography; Extracellul | 1996 |
Efflux of gamma-aminobutyric acid caused by changes in ion concentrations and cell swelling simulating the effect of cerebral ischaemia.
Topics: Animals; Brain Edema; Brain Ischemia; Carrier Proteins; Cell Survival; Culture Techniques; Electroly | 1997 |
Effects of hyperosmolarity and ion substitutions on amino acid efflux from the ischemic rat cerebral cortex.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Brain Edema; Brain Ischemia; Cerebral Cortex; Chlorides | 1999 |
Hyposmotically induced amino acid release from the rat cerebral cortex: role of phospholipases and protein kinases.
Topics: Acetophenones; Alanine; Amino Acids; Animals; Arachidonic Acids; Aspartic Acid; Brain Edema; Cerebra | 1999 |
[Changes of glutamate and gamma-aminobutyric acid contents in brain tissue of brain edema and effects of baicalin on them in rats].
Topics: Animals; Brain; Brain Edema; Female; Flavonoids; gamma-Aminobutyric Acid; Glutamic Acid; Male; Rando | 2000 |
Relationship between epileptic activity and edema formation in the acute phase of cryogenic lesion.
Topics: Animals; Brain Edema; Cold Temperature; Electroencephalography; Epilepsy; gamma-Aminobutyric Acid; G | 1987 |
[The GABA-ergic system and brain edema].
Topics: Animals; Anti-Anxiety Agents; Benactyzine; Benzodiazepines; Benzodiazepinones; Brain Edema; Brain In | 1985 |
[Amino acid level in albino rat brain and liver tissue during acute brain edema].
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Edema; gamma-Aminobutyric Acid; Glutamates; Liver; | 1972 |