gamma-aminobutyric acid has been researched along with Brain Disorders in 99 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cerebral cortex tissue was obtained at autopsy from neonatal Poll Hereford calves with clinically confirmed maple syrup urine disease (MSUD), neonatal Holstein-Friesian calves with clinically confirmed citrullinemia, and matched controls." | 7.68 | Glutamate and gamma-aminobutyric acid neurotransmitter systems in the acute phase of maple syrup urine disease and citrullinemia encephalopathies in newborn calves. ( Dennis, JA; Dodd, PR; Gundlach, AL; Harper, PA; Healy, PJ; Johnston, GA; Williams, SH, 1992) |
| "The association of macrocephaly, dystonia, and bilateral temporal arachnoid cysts, shown either by computed tomography or magnetic resonance imaging, seems to be diagnostic of glutaric aciduria type 1." | 5.29 | Macrocephaly, dystonia, and bilateral temporal arachnoid cysts: glutaric aciduria type 1. ( Casas, C; Fernández, MA; Martínez-Lage, JF; Poza, M; Puche, A; Rodriguez Costa, T, 1994) |
| "The initial diagnosis was of hydrocephalus and bilateral temporal cerebrospinal fluid collections." | 5.29 | Macrocephaly, dystonia, and bilateral temporal arachnoid cysts: glutaric aciduria type 1. ( Casas, C; Fernández, MA; Martínez-Lage, JF; Poza, M; Puche, A; Rodriguez Costa, T, 1994) |
| "In a murine model of intracerebral infection by Cryptococcus neoformans the therapeutic effects of pentoxifylline or dexamethasone were studied alone and in combination with amphotericin B." | 5.29 | Effects of pentoxifylline or dexamethasone in combination with amphotericin B in experimental murine cerebral cryptococcosis: evidence of neuroexcitatory pathogenic mechanisms. ( Angeles-Morales, V; Nava-Ruiz, C; Ostrosky-Zeichner, L; Rios, C; Solis, F; Sotelo, J; Soto-Hernandez, JL; Teixeira, F, 1996) |
| ") showing that activation of the cannabinoid receptor CB1 by the endocannabinoid anandamide protects against excitotoxic damage in a mouse model of kainic acid-induced epilepsy." | 3.72 | Neuroscience. Stout guards of the central nervous system. ( Lichtman, AH; Mechoulam, R, 2003) |
| "Glutamate(Glu), gamma-aminobutyric acid(GABA), and malondialdehyde(MDA) in cerebrospinal fluid (CSF) were measured in 18 children with pneumonia complicated with central nervous system(CNS) damage, 14 children with pneumonia without CNS damage, and 7 children with hypocalcemic tetany." | 3.70 | [Changes of glutamate and GABA in cerebrospinal fluid of patients with pneumonia complicated with central nervous system damage]. ( Lou, Z; Yü, P; Yue, S; Zeng, P, 1999) |
| "Cerebral cortex tissue was obtained at autopsy from neonatal Poll Hereford calves with clinically confirmed maple syrup urine disease (MSUD), neonatal Holstein-Friesian calves with clinically confirmed citrullinemia, and matched controls." | 3.68 | Glutamate and gamma-aminobutyric acid neurotransmitter systems in the acute phase of maple syrup urine disease and citrullinemia encephalopathies in newborn calves. ( Dennis, JA; Dodd, PR; Gundlach, AL; Harper, PA; Healy, PJ; Johnston, GA; Williams, SH, 1992) |
| "Pyridoxine-sensitive seizures characterize severe forms of infantile HPP." | 1.46 | Neuromuscular features of hypophosphatasia. ( Fonta, C; Salles, JP, 2017) |
| "Using a rat model of complex febrile seizures, which are thought to be a precipitating insult of TLE later in life, we report that aberrant migration of neonatal-generated granule cells results in granule cell ectopia that persists into adulthood." | 1.38 | GABAergic excitation after febrile seizures induces ectopic granule cells and adult epilepsy. ( Ichikawa, J; Ikegaya, Y; Koyama, R; Matsuki, N; Miyamoto, D; Muramatsu, R; Sasaki, T; Tao, K, 2012) |
| " Chronic administration of haloperidol (1 mg/kg, i." | 1.35 | Progesterone attenuates neuroleptic-induced orofacial dyskinesia via the activity of its metabolite, allopregnanolone, a positive GABA(A) modulating neurosteroid. ( Bishnoi, M; Chopra, K; Kulkarni, SK, 2008) |
| "Kainic acid (KA) solution was injected stereotaxically into medial and lateral sites of the sensori-motor cortex." | 1.33 | Focal cortical dysplasia: pathophysiological approach. ( Hashizume, K; Hodozuka, A; Tanaka, T; Tsuda, H, 2006) |
| "Several brain disorders, e." | 1.29 | Involvement of endogenous benzodiazepine receptor ligands in brain disorders: therapeutic potential for benzodiazepine antagonists? ( Polc, P, 1995) |
| "The association of macrocephaly, dystonia, and bilateral temporal arachnoid cysts, shown either by computed tomography or magnetic resonance imaging, seems to be diagnostic of glutaric aciduria type 1." | 1.29 | Macrocephaly, dystonia, and bilateral temporal arachnoid cysts: glutaric aciduria type 1. ( Casas, C; Fernández, MA; Martínez-Lage, JF; Poza, M; Puche, A; Rodriguez Costa, T, 1994) |
| "The initial diagnosis was of hydrocephalus and bilateral temporal cerebrospinal fluid collections." | 1.29 | Macrocephaly, dystonia, and bilateral temporal arachnoid cysts: glutaric aciduria type 1. ( Casas, C; Fernández, MA; Martínez-Lage, JF; Poza, M; Puche, A; Rodriguez Costa, T, 1994) |
| "Ketosis is beneficial for seizure control, possibly through induction of cerebral acidosis." | 1.29 | Diet-induced ketosis does not cause cerebral acidosis. ( Al-Mudallal, AS; Harik, SI; LaManna, JC; Lust, WD, 1996) |
| "In a murine model of intracerebral infection by Cryptococcus neoformans the therapeutic effects of pentoxifylline or dexamethasone were studied alone and in combination with amphotericin B." | 1.29 | Effects of pentoxifylline or dexamethasone in combination with amphotericin B in experimental murine cerebral cryptococcosis: evidence of neuroexcitatory pathogenic mechanisms. ( Angeles-Morales, V; Nava-Ruiz, C; Ostrosky-Zeichner, L; Rios, C; Solis, F; Sotelo, J; Soto-Hernandez, JL; Teixeira, F, 1996) |
| "In Japan, acute encephalopathy with hepatic steatosis resembling Reye's syndrome has been reported to occur after treatment with the pantothenic acid antagonist, calcium hopantenate." | 1.28 | Acute encephalopathy with hepatic steatosis induced by pantothenic acid antagonist, calcium hopantenate, in dogs. ( Haratake, J; Horie, A; Ishii, N; Noda, S; Sasaki, A; Umezaki, H, 1991) |
| " Further, each dosing paradigm has been evaluated with a view to experimental error and interactive variables." | 1.27 | Effects of early lead exposure on neurotransmitter systems in the brain. A review with commentary. ( Shellenberger, MK, 1984) |
| "Thus, the seizure-facilitating nigral efferents may be subject to inhibition by both GABA and opiates and may normally be driven by substance P." | 1.27 | Role of the substantia nigra in GABA-mediated anticonvulsant actions. ( Gale, K, 1986) |
| "Thiamine-deficient encephalopathy in the rat is characterized by ataxic gait, loss of righting reflex and curvature of the spine." | 1.26 | Amino acid changes in thiamine-deficient encephalopathy: some implications for the pathogenesis of Friedreich's ataxia. ( Barbeau, A; Butterworth, RF; Hamel, E; Landreville, F, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (33.33) | 18.7374 |
| 1990's | 28 (28.28) | 18.2507 |
| 2000's | 15 (15.15) | 29.6817 |
| 2010's | 16 (16.16) | 24.3611 |
| 2020's | 7 (7.07) | 2.80 |
| Authors | Studies |
|---|---|
| Bruzelius, A | 1 |
| Kidnapillai, S | 1 |
| Drouin-Ouellet, J | 1 |
| Stoker, T | 1 |
| Barker, RA | 1 |
| Rylander Ottosson, D | 1 |
| Zhou, J | 2 |
| Liang, W | 1 |
| Wang, J | 1 |
| Chen, J | 1 |
| Liu, D | 1 |
| Wang, X | 1 |
| Wu, Y | 1 |
| Zhang, Q | 1 |
| Shen, D | 1 |
| Tomita, K | 1 |
| Yamanishi-Taira, S | 1 |
| Igarashi, K | 1 |
| Oogai, Y | 1 |
| Kuwahara, Y | 1 |
| Roudkenar, MH | 1 |
| Roushandeh, AM | 1 |
| Miyawaki, S | 1 |
| Kurimasa, A | 1 |
| Sato, T | 1 |
| Zhou, H | 1 |
| Rao, Z | 1 |
| Zhang, Z | 1 |
| Prévot, T | 1 |
| Sibille, E | 2 |
| Scaduto, P | 1 |
| Sequeira, A | 1 |
| Vawter, MP | 1 |
| Bunney, W | 1 |
| Limon, A | 1 |
| Groc, L | 1 |
| Choquet, D | 1 |
| Niturad, CE | 1 |
| Lev, D | 1 |
| Kalscheuer, VM | 1 |
| Charzewska, A | 1 |
| Schubert, J | 1 |
| Lerman-Sagie, T | 1 |
| Kroes, HY | 1 |
| Oegema, R | 1 |
| Traverso, M | 1 |
| Specchio, N | 1 |
| Lassota, M | 1 |
| Chelly, J | 1 |
| Bennett-Back, O | 1 |
| Carmi, N | 1 |
| Koffler-Brill, T | 1 |
| Iacomino, M | 1 |
| Trivisano, M | 1 |
| Capovilla, G | 1 |
| Striano, P | 1 |
| Nawara, M | 1 |
| Rzonca, S | 1 |
| Fischer, U | 1 |
| Bienek, M | 1 |
| Jensen, C | 1 |
| Hu, H | 1 |
| Thiele, H | 1 |
| Altmüller, J | 1 |
| Krause, R | 1 |
| May, P | 1 |
| Becker, F | 1 |
| Balling, R | 1 |
| Biskup, S | 1 |
| Haas, SA | 1 |
| Nürnberg, P | 1 |
| van Gassen, KLI | 1 |
| Lerche, H | 1 |
| Zara, F | 1 |
| Maljevic, S | 1 |
| Leshinsky-Silver, E | 1 |
| Fonta, C | 1 |
| Salles, JP | 1 |
| Ben-Ari, Y | 1 |
| Marseglia, L | 1 |
| D'Angelo, G | 1 |
| Manti, S | 1 |
| Aversa, S | 1 |
| Arrigo, T | 1 |
| Reiter, RJ | 1 |
| Gitto, E | 1 |
| Han, Q | 1 |
| Cao, C | 1 |
| Ding, Y | 1 |
| So, KF | 1 |
| Wu, W | 1 |
| Qu, Y | 1 |
| Zhou, L | 1 |
| Yasin Wayhs, CA | 1 |
| Tannhauser Barros, HM | 1 |
| Vargas, CR | 1 |
| Prager, EM | 1 |
| Bergstrom, HC | 1 |
| Wynn, GH | 1 |
| Braga, MF | 1 |
| Wang, Y | 1 |
| Zhang, P | 1 |
| Wyskiel, DR | 1 |
| Winter, C | 1 |
| Djodari-Irani, A | 1 |
| Sohr, R | 1 |
| Morgenstern, R | 1 |
| Feldon, J | 1 |
| Juckel, G | 1 |
| Meyer, U | 1 |
| Brill, MS | 1 |
| Ninkovic, J | 1 |
| Winpenny, E | 1 |
| Hodge, RD | 1 |
| Ozen, I | 1 |
| Yang, R | 1 |
| Lepier, A | 1 |
| Gascón, S | 1 |
| Erdelyi, F | 1 |
| Szabo, G | 1 |
| Parras, C | 1 |
| Guillemot, F | 1 |
| Frotscher, M | 1 |
| Berninger, B | 1 |
| Hevner, RF | 1 |
| Raineteau, O | 1 |
| Götz, M | 1 |
| Gharibani, PM | 1 |
| Tiraihi, T | 1 |
| Arabkheradmand, J | 1 |
| Li, F | 1 |
| Liu, X | 1 |
| Su, Z | 1 |
| Sun, R | 1 |
| Di Cristo, G | 2 |
| Pizzorusso, T | 1 |
| Cancedda, L | 1 |
| Sernagor, E | 1 |
| Levy, LM | 1 |
| Degnan, AJ | 1 |
| Koyama, R | 1 |
| Tao, K | 1 |
| Sasaki, T | 2 |
| Ichikawa, J | 1 |
| Miyamoto, D | 1 |
| Muramatsu, R | 1 |
| Matsuki, N | 1 |
| Ikegaya, Y | 1 |
| Sakakibara, T | 1 |
| Sukigara, S | 1 |
| Otsuki, T | 1 |
| Takahashi, A | 1 |
| Kaneko, Y | 1 |
| Kaido, T | 1 |
| Saito, Y | 1 |
| Sato, N | 1 |
| Nakagawa, E | 1 |
| Sugai, K | 1 |
| Sasaki, M | 1 |
| Goto, Y | 1 |
| Itoh, M | 1 |
| Jang, HJ | 1 |
| Yang, YR | 1 |
| Kim, JK | 1 |
| Choi, JH | 1 |
| Seo, YK | 1 |
| Lee, YH | 1 |
| Lee, JE | 1 |
| Ryu, SH | 1 |
| Suh, PG | 1 |
| Yager, JY | 1 |
| Hartfield, DS | 1 |
| Mechoulam, R | 1 |
| Lichtman, AH | 1 |
| Sechi, G | 1 |
| Murgia, B | 1 |
| Sau, G | 1 |
| Peddone, L | 1 |
| Tirotto, A | 1 |
| Barrocu, M | 1 |
| Rosati, G | 1 |
| Prilipko, O | 1 |
| Delavelle, J | 1 |
| Seeck, M | 1 |
| Glorioso, C | 1 |
| Sabatini, M | 1 |
| Unger, T | 1 |
| Hashimoto, T | 2 |
| Monteggia, LM | 1 |
| Lewis, DA | 1 |
| Mirnics, K | 1 |
| Hodozuka, A | 1 |
| Tsuda, H | 1 |
| Hashizume, K | 1 |
| Tanaka, T | 1 |
| Scarabino, T | 1 |
| Giannatempo, GM | 1 |
| Popolizio, T | 1 |
| Tosetti, M | 1 |
| d'Alesio, V | 1 |
| Esposito, F | 1 |
| Di Salle, F | 1 |
| Di Costanzo, A | 1 |
| Bertolino, A | 1 |
| Maggialetti, A | 1 |
| Salvolini, U | 1 |
| Bishnoi, M | 1 |
| Chopra, K | 1 |
| Kulkarni, SK | 1 |
| Pan, JW | 1 |
| Williamson, A | 1 |
| Cavus, I | 1 |
| Hetherington, HP | 1 |
| Zaveri, H | 1 |
| Petroff, OA | 1 |
| Spencer, DD | 1 |
| Walker, JE | 1 |
| Shellenberger, MK | 1 |
| Takeoka, T | 1 |
| Yamamoto, M | 2 |
| Otsuki, S | 1 |
| Miyake, K | 1 |
| Namba, R | 1 |
| Barbosa, ER | 1 |
| Marchiori, PE | 1 |
| Scaff, M | 1 |
| de Assis, JL | 1 |
| Christensen, SE | 1 |
| Dupont, E | 1 |
| Mondrup, K | 1 |
| Olivarius, BF | 1 |
| Orskov, H | 1 |
| Kish, SJ | 5 |
| Perry, TL | 5 |
| Hornykiewicz, O | 3 |
| Polc, P | 1 |
| Hossain, MA | 1 |
| Weiner, N | 1 |
| Sherif, FM | 1 |
| Ahmed, SS | 1 |
| Erecińska, M | 1 |
| Nelson, D | 1 |
| Santamaría, A | 1 |
| Altagracia, M | 1 |
| Solís, F | 2 |
| Kravzov, J | 1 |
| Ordaz, H | 1 |
| Gonzalez, L | 1 |
| Ríos, C | 2 |
| Martínez-Lage, JF | 1 |
| Casas, C | 1 |
| Fernández, MA | 1 |
| Puche, A | 1 |
| Rodriguez Costa, T | 1 |
| Poza, M | 1 |
| Jackson, GD | 1 |
| Williams, SR | 1 |
| Weller, RO | 1 |
| van Bruggen, N | 1 |
| Preece, NE | 1 |
| Williams, SC | 1 |
| Butler, WH | 1 |
| Duncan, JS | 1 |
| Seiler, N | 1 |
| Daune-Anglard, G | 1 |
| Al-Mudallal, AS | 1 |
| LaManna, JC | 1 |
| Lust, WD | 1 |
| Harik, SI | 1 |
| Ostrosky-Zeichner, L | 1 |
| Soto-Hernandez, JL | 1 |
| Angeles-Morales, V | 1 |
| Teixeira, F | 1 |
| Nava-Ruiz, C | 1 |
| Sotelo, J | 1 |
| Saransaari, P | 1 |
| Oja, SS | 1 |
| March, PA | 1 |
| Thrall, MA | 1 |
| Brown, DE | 1 |
| Mitchell, TW | 1 |
| Lowenthal, AC | 1 |
| Walkley, SU | 1 |
| O'Connor, WT | 1 |
| Mora Teruel, F | 1 |
| Granström, ML | 1 |
| Gaily, E | 1 |
| Liukkonen, E | 1 |
| Kawai, N | 1 |
| Gabel, LA | 1 |
| LoTurco, JJ | 1 |
| Inobe, J | 1 |
| Arakawa, T | 1 |
| Mori, T | 1 |
| Kumamoto, T | 1 |
| Tsuda, T | 1 |
| Grachev, ID | 1 |
| Apkarian, AV | 1 |
| Yue, S | 1 |
| Lou, Z | 1 |
| Yü, P | 1 |
| Zeng, P | 1 |
| Sytinsky, IA | 1 |
| Soldatenkov, AT | 1 |
| Lajtha, A | 1 |
| Butterworth, RF | 1 |
| Hamel, E | 1 |
| Landreville, F | 1 |
| Barbeau, A | 1 |
| Pezzuoli, G | 1 |
| Spina, GP | 1 |
| Vassanelli, P | 1 |
| Poemnyĭ, FA | 1 |
| Trubnikov, BM | 1 |
| McBride, WJ | 1 |
| Aprison, MH | 1 |
| Kusano, K | 1 |
| Dodd, PR | 1 |
| Williams, SH | 1 |
| Gundlach, AL | 1 |
| Harper, PA | 1 |
| Healy, PJ | 1 |
| Dennis, JA | 1 |
| Johnston, GA | 1 |
| Rönnbäck, L | 1 |
| Hansson, E | 1 |
| Ronnett, GV | 1 |
| Hester, LD | 1 |
| Nye, JS | 1 |
| Connors, K | 1 |
| Snyder, SH | 1 |
| Aizawa, H | 1 |
| Kwak, S | 1 |
| Shimizu, T | 1 |
| Mannen, T | 1 |
| Noda, S | 1 |
| Haratake, J | 1 |
| Sasaki, A | 1 |
| Ishii, N | 1 |
| Umezaki, H | 1 |
| Horie, A | 1 |
| Hori, A | 2 |
| Hirose, G | 2 |
| Kataoka, S | 2 |
| Tsukada, K | 2 |
| Furui, K | 1 |
| Tonami, H | 2 |
| Minagawa, M | 1 |
| Yamamoto, T | 1 |
| Ichihashi, H | 1 |
| Susel, Z | 1 |
| Nakanishi, T | 1 |
| Funahashi, S | 1 |
| Shimizu, A | 1 |
| Hayashi, A | 1 |
| Kaiya, H | 1 |
| Nishida, A | 1 |
| Gilbert, JJ | 1 |
| Chang, LJ | 1 |
| Mirchandani, L | 1 |
| Shannak, K | 1 |
| Dunn, HG | 1 |
| Ho, HH | 1 |
| Crichton, JU | 1 |
| Wieloch, T | 1 |
| Korf, J | 1 |
| Gramsbergen, JB | 1 |
| Prenen, GH | 1 |
| Go, KG | 1 |
| Sweeney, VP | 2 |
| Gale, K | 1 |
| Dunnett, SB | 1 |
| Isacson, O | 1 |
| Sirinathsinghji, DJ | 1 |
| Clarke, DJ | 1 |
| Björklund, A | 1 |
| Miyazaki, C | 1 |
| Matsuyama, K | 1 |
| Ichikawa, M | 1 |
| Goto, S | 1 |
| Hauser, WA | 1 |
| Ng, SK | 1 |
| Brust, JC | 1 |
| Winder, TR | 1 |
| Minuk, GY | 1 |
| Sargeant, EJ | 1 |
| Seland, TP | 1 |
| Yong, VW | 1 |
| Godolphin, WJ | 2 |
| Sutter, M | 1 |
| Hansen, S | 1 |
| Foulks, JG | 1 |
| Ito, M | 1 |
| Lockwood, AH | 1 |
| von Metzler, A | 1 |
| Nitsch, C | 1 |
| Kimura, A | 1 |
| Yoshida, I | 1 |
| Ono, E | 1 |
| Matsuishi, T | 1 |
| Yoshino, M | 1 |
| Yamashita, F | 1 |
| Shinka, T | 1 |
| Kuhara, T | 1 |
| Johnson, R | 1 |
| Izumi, T | 1 |
| Utsumi, H | 1 |
| Osawa, M | 1 |
| Fukuyama, Y | 1 |
| Price, JD | 1 |
| Reeve, CE | 1 |
| Hikosaka, O | 1 |
| Tanaka, M | 1 |
| Sakamoto, M | 1 |
| Iwamura, Y | 1 |
| Simler, S | 1 |
| Owsianowski, N | 1 |
| Randrianarisoa, H | 1 |
| Ledig, M | 1 |
| Mandel, P | 1 |
| Borromei, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The BrainDrugs-Epilepsy Study: A Prospective Open-label Cohort Precision Medicine Study in Epilepsy[NCT05450822] | 550 participants (Anticipated) | Observational | 2022-02-18 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
23 reviews available for gamma-aminobutyric acid and Brain Disorders
| Article | Year |
|---|---|
Function of the GABAergic System in Diabetic Encephalopathy.
Topics: Adult; Animals; Blood Glucose; Brain Diseases; Diabetes Mellitus; gamma-Aminobutyric Acid; Humans; H | 2023 |
Altered GABA-mediated information processing and cognitive dysfunctions in depression and other brain disorders.
Topics: Brain Diseases; Cognition; Cognitive Dysfunction; Depression; gamma-Aminobutyric Acid; Humans; Inter | 2021 |
Linking glutamate receptor movements and synapse function.
Topics: Brain Diseases; gamma-Aminobutyric Acid; Humans; Neuronal Plasticity; Receptors, Glutamate; Receptor | 2020 |
Analgesic, anxiolytic and anaesthetic effects of melatonin: new potential uses in pediatrics.
Topics: Analgesics; Anesthetics, General; Anti-Anxiety Agents; Anxiety Disorders; Brain Diseases; Child; Ele | 2015 |
GABAergic Modulation in Diabetic Encephalopathy-Related Depression.
Topics: Animals; Brain Diseases; Depression; Diabetes Complications; gamma-Aminobutyric Acid; Humans; Neurot | 2015 |
The basolateral amygdala γ-aminobutyric acidergic system in health and disease.
Topics: Basolateral Nuclear Complex; Brain Diseases; gamma-Aminobutyric Acid; Humans; Interneurons; Signal T | 2016 |
Chandelier Cells in Functional and Dysfunctional Neural Circuits.
Topics: Animals; Axons; Brain Diseases; gamma-Aminobutyric Acid; Nerve Net; Neural Inhibition; Neurons | 2016 |
GABA-based evaluation of neurologic conditions: MR spectroscopy.
Topics: Antipsychotic Agents; Brain Diseases; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Magnetic Re | 2013 |
Phospholipase C-γ1 involved in brain disorders.
Topics: Brain; Brain Diseases; Brain-Derived Neurotrophic Factor; Calcium; gamma-Aminobutyric Acid; Gene Exp | 2013 |
Neurologic manifestations of iron deficiency in childhood.
Topics: Anemia, Iron-Deficiency; Brain Diseases; Child; Child, Preschool; Developmental Disabilities; Dopami | 2002 |
Development of cortical GABAergic circuits and its implications for neurodevelopmental disorders.
Topics: Autistic Disorder; Brain Diseases; Cerebral Cortex; gamma-Aminobutyric Acid; Humans; Interneurons; N | 2007 |
Neurometabolism in human epilepsy.
Topics: Animals; Brain Diseases; Brain Mapping; Carbon Isotopes; Dominance, Cerebral; Electrodes, Implanted; | 2008 |
Glutamate, GABA, and CNS disease: a review.
Topics: Brain; Brain Diseases; Energy Metabolism; Epilepsy; Ethanol; gamma-Aminobutyric Acid; Glutamates; Gl | 1983 |
[Neurotransmitters in the cerebrospinal fluid (author's transl)].
Topics: Acetylcholine; Adolescent; Adult; Age Factors; Aged; Animals; Biogenic Amines; Brain; Brain Diseases | 1981 |
Basic aspects of GABA-transaminase in neuropsychiatric disorders.
Topics: 4-Aminobutyrate Transaminase; Aging; Animals; Blood Platelets; Brain; Brain Diseases; Female; gamma- | 1995 |
Endogenous ornithine in search for CNS functions and therapeutic applications.
Topics: Ammonia; Animals; Brain; Brain Diseases; gamma-Aminobutyric Acid; Humans; Ornithine; Ornithine-Oxo-A | 1993 |
[Recent topics on amino-acid neurotransmitters].
Topics: Amino Acid Sequence; Animals; Brain Diseases; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Molecu | 1999 |
[Excitatory amino acid and their involvement in pathological processes in the brain].
Topics: Animals; Aspartic Acid; Brain Diseases; gamma-Aminobutyric Acid; Humans; N-Methylaspartate | 1990 |
Neurochemical correlates to selective neuronal vulnerability.
Topics: Adenosine; Afferent Pathways; Animals; Aspartic Acid; Brain Diseases; Brain Ischemia; Calcium; Chlor | 1985 |
Cation shifts and excitotoxins in Alzheimer and Huntington disease and experimental brain damage.
Topics: Aged; Alzheimer Disease; Amino Acids; Animals; Brain; Brain Diseases; Calcium; Cations; gamma-Aminob | 1986 |
Striatal grafts in the ibotenic acid-lesioned neostriatum: functional studies.
Topics: Animals; Brain Diseases; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Globus Pallidus; Iboten | 1988 |
Alcohol and fits.
Topics: Adolescent; Adult; Aged; Alcoholic Intoxication; Alcoholism; Anticonvulsants; Brain Chemistry; Brain | 1985 |
[Some therapeutic effects of GABA in neurology (author's transl)].
Topics: Aminobutyrates; Brain; Brain Diseases; Brain Injuries; Cerebrovascular Disorders; Coma; Epilepsy; ga | 1974 |
1 trial available for gamma-aminobutyric acid and Brain Disorders
| Article | Year |
|---|---|
Treatment of infantile spasms: results of a population-based study with vigabatrin as the first drug for spasms.
Topics: 4-Aminobutyrate Transaminase; Adrenocorticotropic Hormone; Anticonvulsants; Brain Diseases; Child; C | 1999 |
75 other studies available for gamma-aminobutyric acid and Brain Disorders
| Article | Year |
|---|---|
Reprogramming Human Adult Fibroblasts into GABAergic Interneurons.
Topics: Adult; Brain Diseases; Cell Differentiation; Cellular Reprogramming; Cognitive Dysfunction; Fibrobla | 2021 |
An epileptic encephalopathy associated GABRG2 missense mutation leads to pre- and postsynaptic defects in zebrafish.
Topics: Animals; Brain Diseases; gamma-Aminobutyric Acid; Humans; Mutation; Mutation, Missense; Receptors, G | 2022 |
Oxytocin ameliorates KCC2 decrease induced by oral bacteria-derived LPS that affect rat primary cultured cells and PC-12 cells.
Topics: Animals; Brain Diseases; Cells, Cultured; Escherichia coli; gamma-Aminobutyric Acid; Glycogen Syntha | 2022 |
Preservation of global synaptic excitatory to inhibitory ratio during long postmortem intervals.
Topics: Adult; Animals; Brain; Brain Diseases; Excitatory Postsynaptic Potentials; Female; gamma-Aminobutyri | 2020 |
Rare GABRA3 variants are associated with epileptic seizures, encephalopathy and dysmorphic features.
Topics: Adolescent; Adult; Animals; Brain Diseases; Child; Child, Preschool; Cleft Palate; Developmental Dis | 2017 |
Neuromuscular features of hypophosphatasia.
Topics: Adult; Alkaline Phosphatase; Animals; Biomarkers; Brain Diseases; Chronic Pain; Disease Models, Anim | 2017 |
Neuropaediatric and neuroarchaeology: understanding development to correct brain disorders.
Topics: Biological Evolution; Brain; Brain Diseases; gamma-Aminobutyric Acid; Humans; Mutation; Neuronal Pla | 2013 |
Plasticity of motor network and function in the absence of corticospinal projection.
Topics: Acetylcholine; Animals; Brain Diseases; Cadherins; Choline O-Acetyltransferase; Disease Models, Anim | 2015 |
Reduced Somatostatin Expression or Somatostatin-Positive Gamma-Aminobutyric Acid Neurons: A Shared Pathology Across Brain Disorders.
Topics: Brain Diseases; gamma-Aminobutyric Acid; Humans; Neurons; Somatostatin | 2017 |
Prenatal immune activation leads to multiple changes in basal neurotransmitter levels in the adult brain: implications for brain disorders of neurodevelopmental origin such as schizophrenia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Brain Diseases; Chromatography, High Press | 2009 |
Adult generation of glutamatergic olfactory bulb interneurons.
Topics: Adult Stem Cells; Age Factors; Animals; Axons; Basic Helix-Loop-Helix Transcription Factors; Biomark | 2009 |
In vitro differentiation of GABAergic cells from bone marrow stromal cells using potassium chloride as inducer.
Topics: Animals; Bone Marrow Cells; Brain Diseases; Cell Culture Techniques; Cell Differentiation; Cell Tran | 2010 |
Acidosis leads to brain dysfunctions through impairing cortical GABAergic neurons.
Topics: Acidosis; Animals; Brain Diseases; Cells, Cultured; Cerebral Cortex; gamma-Aminobutyric Acid; Hydrog | 2011 |
GABAergic circuit development and its implication for CNS disorders.
Topics: Animals; Brain Diseases; Central Nervous System; gamma-Aminobutyric Acid; Humans; Interneurons; Nerv | 2011 |
GABAergic excitation after febrile seizures induces ectopic granule cells and adult epilepsy.
Topics: Animals; Animals, Suckling; Brain Diseases; Bumetanide; Cell Lineage; Cell Movement; Choristoma; Den | 2012 |
Imbalance of interneuron distribution between neocortex and basal ganglia: consideration of epileptogenesis of focal cortical dysplasia.
Topics: Adolescent; Brain Diseases; Calbindin 2; Calbindins; Case-Control Studies; Caudate Nucleus; Cell Cou | 2012 |
Neuroscience. Stout guards of the central nervous system.
Topics: Animals; Anticonvulsants; Arachidonic Acids; Brain; Brain Diseases; Cannabidiol; Cannabinoid Recepto | 2003 |
Asterixis and toxic encephalopathy induced by gabapentin.
Topics: Acetates; Aged; Amines; Anticonvulsants; Brain; Brain Diseases; Carbamazepine; Cyclohexanecarboxylic | 2004 |
Pregabalin-withdrawal encephalopathy and splenial edema.
Topics: Aged, 80 and over; Anticonvulsants; Brain Diseases; Female; gamma-Aminobutyric Acid; Humans; Pregaba | 2006 |
Specificity and timing of neocortical transcriptome changes in response to BDNF gene ablation during embryogenesis or adulthood.
Topics: Animals; Brain Diseases; Brain-Derived Neurotrophic Factor; Crosses, Genetic; Doxycycline; gamma-Ami | 2006 |
Focal cortical dysplasia: pathophysiological approach.
Topics: Adolescent; Animals; Animals, Newborn; Autoradiography; Behavior, Animal; Brain Diseases; Brain Mapp | 2006 |
3.0-T functional brain imaging: a 5-year experience.
Topics: Artifacts; Aspartic Acid; Brain; Brain Diseases; Brain Neoplasms; Cerebral Arteries; Cerebral Cortex | 2007 |
Progesterone attenuates neuroleptic-induced orofacial dyskinesia via the activity of its metabolite, allopregnanolone, a positive GABA(A) modulating neurosteroid.
Topics: Animals; Antipsychotic Agents; Brain Diseases; Control Groups; Disease Models, Animal; Dopamine; Dys | 2008 |
Effects of early lead exposure on neurotransmitter systems in the brain. A review with commentary.
Topics: Acetylcholine; Amino Acids; Animals; Animals, Newborn; Brain; Brain Diseases; Catecholamines; Cholin | 1984 |
[Lumbar cerebrospinal fluid levels of GABA, HVA and 5HIAA in various patients with choreic movement and effects with isoniazid treatment].
Topics: Acanthocytes; Adult; Aged; Atrophy; Brain Diseases; Chorea; gamma-Aminobutyric Acid; Homovanillic Ac | 1983 |
[Huntington chorea: report of 16 cases].
Topics: Adult; Aged; Brain Diseases; Chlorpromazine; Dementia; Diagnosis, Differential; Female; gamma-Aminob | 1983 |
Parkinson's disease and benign essential tremor: somatostatin-like immunoreactivity in the cerebrospinal fluid.
Topics: Adult; Aged; Alzheimer Disease; Atrophy; Brain Diseases; Female; gamma-Aminobutyric Acid; Humans; Hu | 1984 |
Benzodiazepine receptor binding in cerebellar cortex: observations in olivopontocerebellar atrophy.
Topics: Atrophy; Benzodiazepines; Brain; Brain Diseases; Cerebellar Cortex; Cerebellum; Flunitrazepam; gamma | 1984 |
Involvement of endogenous benzodiazepine receptor ligands in brain disorders: therapeutic potential for benzodiazepine antagonists?
Topics: Animals; Benzodiazepines; Brain Diseases; Central Nervous System Diseases; gamma-Aminobutyric Acid; | 1995 |
Interactions of dopaminergic and GABAergic neurotransmission: impact of 6-hydroxydopamine lesions into the substantia nigra of rats.
Topics: Animals; Brain Diseases; Corpus Striatum; Cyclic AMP; Dopamine; Dopamine Agonists; Dopamine Antagoni | 1995 |
Effects of 3-nitropropionic acid on synaptosomal energy and transmitter metabolism: relevance to neurodegenerative brain diseases.
Topics: Adenosine Triphosphate; Animals; Brain Diseases; Cell Death; Creatine; Energy Metabolism; gamma-Amin | 1994 |
Kynurenine and probenecid prevent quinolinic acid-induced neurotoxicity in rat corpus striatum.
Topics: Animals; Brain Diseases; gamma-Aminobutyric Acid; Kynurenine; Male; Neostriatum; Probenecid; Quinoli | 1994 |
Macrocephaly, dystonia, and bilateral temporal arachnoid cysts: glutaric aciduria type 1.
Topics: Arachnoid Cysts; Brain; Brain Diseases; Carnitine; Dystonia; Female; gamma-Aminobutyric Acid; Glutar | 1994 |
Vigabatrin-induced lesions in the rat brain demonstrated by quantitative magnetic resonance imaging.
Topics: Animals; Anticonvulsants; Brain; Brain Diseases; Cerebellum; gamma-Aminobutyric Acid; Glial Fibrilla | 1994 |
Diet-induced ketosis does not cause cerebral acidosis.
Topics: Acidosis; Animals; Brain; Brain Diseases; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; gam | 1996 |
Effects of pentoxifylline or dexamethasone in combination with amphotericin B in experimental murine cerebral cryptococcosis: evidence of neuroexcitatory pathogenic mechanisms.
Topics: Amphotericin B; Animals; Antifungal Agents; Brain; Brain Chemistry; Brain Diseases; Cryptococcosis; | 1996 |
Enhanced GABA release in cell-damaging conditions in the adult and developing mouse hippocampus.
Topics: Animals; Animals, Newborn; Brain Diseases; Brain Ischemia; Calcium; Culture Media; Female; Free Radi | 1997 |
GABAergic neuroaxonal dystrophy and other cytopathological alterations in feline Niemann-Pick disease type C.
Topics: Age Factors; Animals; Brain Diseases; Cats; Child, Preschool; Disease Models, Animal; gamma-Aminobut | 1997 |
Functional neuroanatomy of the basal ganglia as studied by dual-probe microdialysis.
Topics: Animals; Brain Diseases; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine D2 Receptor Antagoni | 1998 |
[Interaction of neurotransmitters in specific circuits of the brain].
Topics: Aging; Animals; Brain; Brain Diseases; Cerebral Cortex; Dopamine; gamma-Aminobutyric Acid; Glutamic | 1998 |
Electrophysiological and morphological characterization of neurons within neocortical ectopias.
Topics: Afferent Pathways; Animals; Brain Diseases; Choristoma; Electrophysiology; Epilepsy; Female; gamma-A | 2001 |
[Acquired pendular nystagmus associated with the lesion of tegmentum mesencephali in a patient with probable multiple sclerosis].
Topics: Adult; Brain Diseases; Clonazepam; Diazepam; Female; gamma-Aminobutyric Acid; Humans; Multiple Scler | 2000 |
Multi-chemical networking profile of the living human brain: potential relevance to molecular studies of cognition and behavior in normal and diseased brain.
Topics: Adult; Analysis of Variance; Behavior; Brain; Brain Diseases; Cognition; Factor Analysis, Statistica | 2002 |
[Changes of glutamate and GABA in cerebrospinal fluid of patients with pneumonia complicated with central nervous system damage].
Topics: Brain Diseases; Child; Child, Preschool; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Inf | 1999 |
Neurochemical basis of the therapeutic effect of gamma-aminobutyric acid and its derivatives.
Topics: 4-Aminobutyrate Transaminase; Animals; Axonal Transport; Brain; Brain Diseases; Epilepsy; gamma-Amin | 1978 |
Amino acid changes in thiamine-deficient encephalopathy: some implications for the pathogenesis of Friedreich's ataxia.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Diseases; Friedreich Ataxia; gamma-Aminobutyric Ac | 1979 |
[Current aspects of the surgery of portal hypertension (PH)].
Topics: Animals; Brain; Brain Diseases; Catecholamines; Enzymes; Esophageal and Gastric Varices; gamma-Amino | 1975 |
[Treatment of infectious-toxic and traumatic lesion, of the hypothalamic region with aminalon and gammalon].
Topics: Adult; Aminobutyrates; Brain Diseases; Brain Injuries; Epilepsy; Female; gamma-Aminobutyric Acid; Hu | 1975 |
Contents of several amino acids in the cerebellum, brain stem and cerebrum of the 'staggerer', 'weaver' and 'nervous' neurologically mutant mice.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Brain Diseases; Brain Stem; Cerebellum; Disease | 1976 |
Glutamate and gamma-aminobutyric acid neurotransmitter systems in the acute phase of maple syrup urine disease and citrullinemia encephalopathies in newborn calves.
Topics: Acute-Phase Reaction; Animals; Animals, Newborn; Aspartic Acid; Brain Diseases; Cattle; Cattle Disea | 1992 |
Chronic encephalopathies induced by mercury or lead: aspects of underlying cellular and molecular mechanisms.
Topics: Astrocytes; Brain Diseases; Cells, Cultured; Chronic Disease; gamma-Aminobutyric Acid; Glutamates; L | 1992 |
Human cortical neuronal cell line: establishment from a patient with unilateral megalencephaly.
Topics: 1-Methyl-3-isobutylxanthine; Brain Diseases; Bucladesine; Cell Differentiation; Cell Line; Cerebral | 1990 |
Determination of GABAergic pallidothalamic termination in human brain.
Topics: Adult; Brain Diseases; gamma-Aminobutyric Acid; Globus Pallidus; Humans; Thalamus | 1991 |
Acute encephalopathy with hepatic steatosis induced by pantothenic acid antagonist, calcium hopantenate, in dogs.
Topics: Acute Disease; Animals; Brain Diseases; Dogs; Fatty Liver; Female; gamma-Aminobutyric Acid; Liver; M | 1991 |
Delayed postanoxic encephalopathy after strangulation. Serial neuroradiological and neurochemical studies.
Topics: Adolescent; Asphyxia; Brain; Brain Diseases; Caudate Nucleus; Crime; Dopamine; Electroencephalograph | 1991 |
A case of the Rett syndrome with acute encephalopathy induced during calcium hopantenate treatment.
Topics: Acute Disease; Blood Glucose; Brain Diseases; Carboxylic Acids; Child, Preschool; Female; gamma-Amin | 1991 |
[Delayed postanoxic encephalopathy after strangulation--the serial neuroradiological and neurochemical studies].
Topics: Adolescent; Asphyxia; Brain; Brain Diseases; Caudate Nucleus; Crime; Dopamine; Electroencephalograph | 1990 |
Urinary organic acids in elderly Japanese patients with ketosis and encephalopathy who have taken panto-yl-gamma-aminobutyrate, calcium salt (calcium hopantenate, HOPA).
Topics: Acidosis; Aged; Brain Diseases; Carboxylic Acids; gamma-Aminobutyric Acid; Humans; Ketosis; Male; Pa | 1990 |
[Clinical significance of gamma-aminobutyric acid assay].
Topics: Brain Diseases; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; gamma-Aminobutyr | 1990 |
Brain neurotransmitter abnormalities in neuronal intranuclear inclusion body disorder.
Topics: Adolescent; Brain; Brain Diseases; Dopamine; Female; gamma-Aminobutyric Acid; Homovanillic Acid; Hum | 1985 |
Cerebrospinal fluid values for monoamine metabolites, gamma-aminobutyric acid, and other amino compounds in Rett syndrome.
Topics: Adolescent; Biogenic Amines; Brain Diseases; Child; Child Behavior Disorders; Child, Preschool; Deve | 1988 |
Brain gamma-aminobutyric acid and benzodiazepine receptor binding in dialysis encephalopathy.
Topics: Benzodiazepinones; Brain Diseases; Flunitrazepam; Frontal Lobe; gamma-Aminobutyric Acid; Humans; Mid | 1985 |
Role of the substantia nigra in GABA-mediated anticonvulsant actions.
Topics: Aminocaproates; Aminooxyacetic Acid; Animals; Anticonvulsants; Brain; Brain Diseases; Denervation; D | 1986 |
Effect of sodium valproate (VPA) on cerebral amino acids: mechanism of gamma-aminobutyric acid (GABA) elevation and possible causal relation of VPA-induced encephalopathy and glutamine level.
Topics: Amino Acids; Animals; Brain Chemistry; Brain Diseases; gamma-Aminobutyric Acid; Glutamine; Male; Mic | 1988 |
Alcohol, seizures, and epilepsy.
Topics: Alcoholic Intoxication; Alcoholism; Animals; Brain Diseases; Epilepsy; Ethanol; gamma-Aminobutyric A | 1988 |
gamma-Aminobutyric acid (GABA) and sepsis-related encephalopathy.
Topics: Animals; Bacterial Infections; Brain Diseases; gamma-Aminobutyric Acid; Male; Rats; Rats, Inbred Str | 1988 |
Inability to produce a model of dialysis encephalopathy in the rat by aluminum administration.
Topics: Aluminum Hydroxide; Animals; Brain Chemistry; Brain Diseases; Choline O-Acetyltransferase; Disease M | 1987 |
Metabolic encephalopathies: opportunities and challenges.
Topics: Ammonia; Animals; Brain; Brain Diseases; gamma-Aminobutyric Acid; Hepatic Encephalopathy; Humans; Me | 1987 |
[Round table. GABA and neuro-psychiatric pathology. Fez (Morocco), 24-25 October 1986. Proceedings].
Topics: Animals; Brain Diseases; gamma-Aminobutyric Acid; Humans; Mental Disorders | 1987 |
Carcinogenesis and the central nervous system.
Topics: Animals; Antineoplastic Agents; Brain; Brain Diseases; Central Nervous System Agents; Electroencepha | 1986 |
Acute encephalopathy with hyperammonemia and dicarboxylic aciduria during calcium hopantenate therapy: a patient report.
Topics: Acute Disease; Ammonia; Brain Diseases; Child, Preschool; Female; gamma-Aminobutyric Acid; Humans; P | 1986 |
[A clinico-biochemical study of acute encephalopathy in patients treated with Ca-hopantenate].
Topics: Acute Disease; Adolescent; Adult; Age Factors; Blood Chemical Analysis; Brain Diseases; Child; Child | 1985 |
Brain gamma-aminobutyric acid deficiency in dialysis encephalopathy.
Topics: Adult; Aluminum; Brain Chemistry; Brain Diseases; Cerebral Cortex; Choline O-Acetyltransferase; gamm | 1985 |
Deficits in manipulative behaviors induced by local injections of muscimol in the first somatosensory cortex of the conscious monkey.
Topics: Animals; Brain Diseases; Brain Mapping; Female; gamma-Aminobutyric Acid; Hand; Macaca; Motor Skills; | 1985 |
Biosynthesis of free amino acids in the brain of Jimpy mice.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Autoanalysis; Brain; Brain Diseases; Carbon Radioisoto | 1974 |