gamma-aminobutyric acid has been researched along with Bone Cancer in 11 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the analgesic effect of pregabalin combined with intrathecal sufentanil infusion for the treatment of breakthrough pain in patients with bone metastases." | 9.19 | [Pregabalin combined with intrathecal sufentanil infusion for breakthrough pain in patients with bone metastases]. ( Cao, Q; Gu, S; Huang, D; Wu, L; Xu, H, 2014) |
| "A total of 60 breakthrough pain patients with bone metastases were randomly divided to 3 groups: group A (pregabalin combined with intrathecal sufentanil infusion group, n=20), group B (placebo combined with intrathecal sufentanil infusion group, n=20) and group C (oral morphine sulfate controlled-release tablet group, n=20)." | 9.19 | [Pregabalin combined with intrathecal sufentanil infusion for breakthrough pain in patients with bone metastases]. ( Cao, Q; Gu, S; Huang, D; Wu, L; Xu, H, 2014) |
| "Pregabalin combined with intrathecal sufentanil infusion can effectively relieve breakthrough pain in patients with bone metastases." | 9.19 | [Pregabalin combined with intrathecal sufentanil infusion for breakthrough pain in patients with bone metastases]. ( Cao, Q; Gu, S; Huang, D; Wu, L; Xu, H, 2014) |
| "A rat model of cancer-induced bone pain using the MRMT-1 cell line injected into the tibia was established to investigate the efficacy of acute (10, 30, 100 mg/kg) and chronic (30 mg/kg) systemic gabapentin on electrophysiological superficial dorsal horn neuronal responses to natural and noxious electrical stimuli, as well as on pain-related behavior." | 7.73 | Gabapentin normalizes spinal neuronal responses that correlate with behavior in a rat model of cancer-induced bone pain. ( Dickenson, AH; Donovan-Rodriguez, T; Urch, CE, 2005) |
| "To evaluate the analgesic effect of pregabalin combined with intrathecal sufentanil infusion for the treatment of breakthrough pain in patients with bone metastases." | 6.79 | [Pregabalin combined with intrathecal sufentanil infusion for breakthrough pain in patients with bone metastases]. ( Cao, Q; Gu, S; Huang, D; Wu, L; Xu, H, 2014) |
| "A total of 60 breakthrough pain patients with bone metastases were randomly divided to 3 groups: group A (pregabalin combined with intrathecal sufentanil infusion group, n=20), group B (placebo combined with intrathecal sufentanil infusion group, n=20) and group C (oral morphine sulfate controlled-release tablet group, n=20)." | 6.79 | [Pregabalin combined with intrathecal sufentanil infusion for breakthrough pain in patients with bone metastases]. ( Cao, Q; Gu, S; Huang, D; Wu, L; Xu, H, 2014) |
| "Pregabalin combined with intrathecal sufentanil infusion can effectively relieve breakthrough pain in patients with bone metastases." | 6.79 | [Pregabalin combined with intrathecal sufentanil infusion for breakthrough pain in patients with bone metastases]. ( Cao, Q; Gu, S; Huang, D; Wu, L; Xu, H, 2014) |
| "Cancer-induced bone pain is a major clinical problem for which current treatments lack full efficacy." | 5.33 | Gabapentin normalizes spinal neuronal responses that correlate with behavior in a rat model of cancer-induced bone pain. ( Dickenson, AH; Donovan-Rodriguez, T; Urch, CE, 2005) |
| "To evaluate the analgesic effect of pregabalin combined with intrathecal sufentanil infusion for the treatment of breakthrough pain in patients with bone metastases." | 5.19 | [Pregabalin combined with intrathecal sufentanil infusion for breakthrough pain in patients with bone metastases]. ( Cao, Q; Gu, S; Huang, D; Wu, L; Xu, H, 2014) |
| "A total of 60 breakthrough pain patients with bone metastases were randomly divided to 3 groups: group A (pregabalin combined with intrathecal sufentanil infusion group, n=20), group B (placebo combined with intrathecal sufentanil infusion group, n=20) and group C (oral morphine sulfate controlled-release tablet group, n=20)." | 5.19 | [Pregabalin combined with intrathecal sufentanil infusion for breakthrough pain in patients with bone metastases]. ( Cao, Q; Gu, S; Huang, D; Wu, L; Xu, H, 2014) |
| "Pregabalin combined with intrathecal sufentanil infusion can effectively relieve breakthrough pain in patients with bone metastases." | 5.19 | [Pregabalin combined with intrathecal sufentanil infusion for breakthrough pain in patients with bone metastases]. ( Cao, Q; Gu, S; Huang, D; Wu, L; Xu, H, 2014) |
| " Based on the need for new approaches in that field the effect of systemic administration of lacosamide (SPM 927, (R)-2-acetamido-N-benzyl-3-methoxypropionamide, previously referred to as harkoseride or ADD 234037), a member of a series of functionalized amino acids that were specifically synthesized as anticonvulsive drug candidates, was examined in rats in a tumor-induced bone cancer pain model and in a chemotherapy-induced neuropathic pain model." | 3.74 | Antinociceptive efficacy of lacosamide in rat models for tumor- and chemotherapy-induced cancer pain. ( Bain, SC; Beyreuther, BK; Brot, MD; Callizot, N; Feldman, R; Stöhr, T, 2007) |
| "A rat model of cancer-induced bone pain using the MRMT-1 cell line injected into the tibia was established to investigate the efficacy of acute (10, 30, 100 mg/kg) and chronic (30 mg/kg) systemic gabapentin on electrophysiological superficial dorsal horn neuronal responses to natural and noxious electrical stimuli, as well as on pain-related behavior." | 3.73 | Gabapentin normalizes spinal neuronal responses that correlate with behavior in a rat model of cancer-induced bone pain. ( Dickenson, AH; Donovan-Rodriguez, T; Urch, CE, 2005) |
| "To evaluate the analgesic effect of pregabalin combined with intrathecal sufentanil infusion for the treatment of breakthrough pain in patients with bone metastases." | 2.79 | [Pregabalin combined with intrathecal sufentanil infusion for breakthrough pain in patients with bone metastases]. ( Cao, Q; Gu, S; Huang, D; Wu, L; Xu, H, 2014) |
| "A total of 60 breakthrough pain patients with bone metastases were randomly divided to 3 groups: group A (pregabalin combined with intrathecal sufentanil infusion group, n=20), group B (placebo combined with intrathecal sufentanil infusion group, n=20) and group C (oral morphine sulfate controlled-release tablet group, n=20)." | 2.79 | [Pregabalin combined with intrathecal sufentanil infusion for breakthrough pain in patients with bone metastases]. ( Cao, Q; Gu, S; Huang, D; Wu, L; Xu, H, 2014) |
| "Pregabalin combined with intrathecal sufentanil infusion can effectively relieve breakthrough pain in patients with bone metastases." | 2.79 | [Pregabalin combined with intrathecal sufentanil infusion for breakthrough pain in patients with bone metastases]. ( Cao, Q; Gu, S; Huang, D; Wu, L; Xu, H, 2014) |
| "Delirium is still one of the most common and distressing symptoms in palliative care patients." | 1.38 | Reversible delirium in an advanced cancer patient. ( Jagsch, C; Kierner, KA; Watzke, HH, 2012) |
| " It has also been reported that pregabalin used with oxycodine reveals analgesic effect with smaller dosage than pregabalin alone." | 1.38 | [Case of acute exacerbation of neuropathic cancer pain rapidly relieved by simultaneous oral intake of immediate release oxycodone and pregabalin]. ( Baba, M; Gomwo, I, 2012) |
| "In the vincristine-induced neuropathic pain model, lacosamide attenuated thermal allodynia, on the cold plate (4 degrees C), at 10 and 30 mg/kg, and in the warm (38 degrees C) and hot plate (52 degrees C) even at 3 mg/kg." | 1.34 | Antinociceptive efficacy of lacosamide in rat models for tumor- and chemotherapy-induced cancer pain. ( Bain, SC; Beyreuther, BK; Brot, MD; Callizot, N; Feldman, R; Stöhr, T, 2007) |
| "Gabapentin, which has been suggested as an adjuvant analgesic for neuropathic pain introduced orally, rapidly and significantly alleviated his pain and we could subsequently dispense with ketamine and mexiletine." | 1.34 | [Gabapentin mitigates neuropathic pain in cancer patients--a case report]. ( Okada, M; Shinjo, T, 2007) |
| "His neuropathic pain was not sufficiently responsive to the combination therapy of opioids, non-steroidal antiinflammatory drugs (NSAIDs), continuous infusion of subcutaneous ketamine and oral mexiletine." | 1.34 | [Gabapentin mitigates neuropathic pain in cancer patients--a case report]. ( Okada, M; Shinjo, T, 2007) |
| "Cancer-induced bone pain is a major clinical problem for which current treatments lack full efficacy." | 1.33 | Gabapentin normalizes spinal neuronal responses that correlate with behavior in a rat model of cancer-induced bone pain. ( Dickenson, AH; Donovan-Rodriguez, T; Urch, CE, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 6 (54.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Corona-Ramos, JN | 1 |
| Déciga-Campos, M | 1 |
| Romero-Piña, M | 1 |
| Medina, LA | 1 |
| Martínez-Racine, I | 1 |
| Jaramillo-Morales, OA | 1 |
| García-López, P | 1 |
| López-Muñoz, FJ | 1 |
| Ge, MM | 1 |
| Chen, SP | 1 |
| Zhou, YQ | 1 |
| Li, Z | 1 |
| Tian, XB | 1 |
| Gao, F | 1 |
| Manyande, A | 1 |
| Tian, YK | 1 |
| Yang, H | 1 |
| Cao, Q | 1 |
| Huang, D | 1 |
| Xu, H | 1 |
| Wu, L | 1 |
| Gu, S | 1 |
| Takasu, K | 1 |
| Ogawa, K | 1 |
| Nakamura, A | 1 |
| Kanbara, T | 1 |
| Ono, H | 1 |
| Tomii, T | 1 |
| Morioka, Y | 1 |
| Hasegawa, M | 1 |
| Shibasaki, M | 1 |
| Mori, T | 1 |
| Suzuki, T | 1 |
| Sakaguchi, G | 1 |
| Caraceni, A | 1 |
| Zecca, E | 1 |
| Martini, C | 1 |
| Pigni, A | 1 |
| Bracchi, P | 1 |
| Menéndez, L | 1 |
| Hidalgo, A | 1 |
| Meana, A | 1 |
| Poras, H | 1 |
| Fournié-Zaluski, MC | 1 |
| Roques, BP | 1 |
| Baamonde, A | 1 |
| Kierner, KA | 1 |
| Jagsch, C | 1 |
| Watzke, HH | 1 |
| Baba, M | 1 |
| Gomwo, I | 1 |
| Donovan-Rodriguez, T | 1 |
| Dickenson, AH | 1 |
| Urch, CE | 1 |
| Beyreuther, BK | 1 |
| Callizot, N | 1 |
| Brot, MD | 1 |
| Feldman, R | 1 |
| Bain, SC | 1 |
| Stöhr, T | 1 |
| Okada, M | 1 |
| Shinjo, T | 1 |
1 trial available for gamma-aminobutyric acid and Bone Cancer
| Article | Year |
|---|---|
[Pregabalin combined with intrathecal sufentanil infusion for breakthrough pain in patients with bone metastases].
Topics: Analgesics, Opioid; Bone Neoplasms; Breakthrough Pain; gamma-Aminobutyric Acid; Humans; Injections, | 2014 |
10 other studies available for gamma-aminobutyric acid and Bone Cancer
| Article | Year |
|---|---|
The Effect of Gabapentin and Tramadol in Cancer Pain Induced by Glioma Cell in Rat Femur.
Topics: Amines; Analgesics; Animals; Bone Neoplasms; Brain Neoplasms; Cancer Pain; Cell Line, Tumor; Cell Su | 2017 |
The therapeutic potential of GABA in neuron-glia interactions of cancer-induced bone pain.
Topics: Animals; Bone Neoplasms; Cancer Pain; Cell Communication; Cell Line, Tumor; Female; GABA Plasma Memb | 2019 |
Enhanced GABAergic synaptic transmission at VLPAG neurons and potent modulation by oxycodone in a bone cancer pain model.
Topics: Analgesics, Opioid; Animals; Bone Neoplasms; Cell Line, Tumor; G Protein-Coupled Inwardly-Rectifying | 2015 |
Gabapentin for breakthrough pain due to bone metastases.
Topics: Amines; Analgesics; Bone Neoplasms; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid | 2008 |
Inhibition of osteosarcoma-induced thermal hyperalgesia in mice by the orally active dual enkephalinase inhibitor PL37. Potentiation by gabapentin.
Topics: Administration, Oral; Amines; Analgesics; Animals; Bone Neoplasms; Cyclohexanecarboxylic Acids; Disu | 2008 |
Reversible delirium in an advanced cancer patient.
Topics: Amines; Analgesics; Analgesics, Opioid; Bone Neoplasms; Breast Neoplasms; Carcinoma, Intraductal, No | 2012 |
[Case of acute exacerbation of neuropathic cancer pain rapidly relieved by simultaneous oral intake of immediate release oxycodone and pregabalin].
Topics: Acute Disease; Administration, Oral; Adult; Bone Neoplasms; Drug Combinations; gamma-Aminobutyric Ac | 2012 |
Gabapentin normalizes spinal neuronal responses that correlate with behavior in a rat model of cancer-induced bone pain.
Topics: Amines; Analgesics; Animals; Behavior, Animal; Bone Neoplasms; Cell Line, Tumor; Cyclohexanecarboxyl | 2005 |
Antinociceptive efficacy of lacosamide in rat models for tumor- and chemotherapy-induced cancer pain.
Topics: Acetamides; Amines; Analgesics; Animals; Antineoplastic Agents, Phytogenic; Bone Neoplasms; Cyclohex | 2007 |
[Gabapentin mitigates neuropathic pain in cancer patients--a case report].
Topics: Adenocarcinoma; Amines; Analgesics; Bone Neoplasms; Cyclohexanecarboxylic Acids; Gabapentin; gamma-A | 2007 |