gamma-aminobutyric acid has been researched along with Bladder, Overactive in 5 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gabapentin treatment with acceptable safety profile, improves OAB symptoms and HRQOL domains." | 2.87 | Efficacy and Safety of Gabapentin in Comparison to Solifenacin Succinate in Adult Overactive Bladder Treatment. ( Balingit, JC; Chua, ME; Esmeňa, EB; Morales, ML; See, MC, 2018) |
| " Adverse event were monitored and summarized." | 2.87 | Efficacy and Safety of Gabapentin in Comparison to Solifenacin Succinate in Adult Overactive Bladder Treatment. ( Balingit, JC; Chua, ME; Esmeňa, EB; Morales, ML; See, MC, 2018) |
| "Gabapentin was prescribed as an add-on therapy." | 2.78 | Gabapentin: a novel drug as add-on therapy in cases of refractory overactive bladder in children. ( Ansari, MS; Bharti, A; Kapoor, R; Kumar, R; Ranjan, P; Srivastava, A, 2013) |
| " Treatments were generally well tolerated; discontinuation rates due to adverse events were 4%, 2%, 5%, 0%, and 1% with standard- and low-dose pregabalin/tolterodine ER, pregabalin, tolterodine ER, and placebo, respectively." | 2.76 | Investigation of the clinical efficacy and safety of pregabalin alone or combined with tolterodine in female subjects with idiopathic overactive bladder. ( Cossons, NH; Darekar, A; Marencak, J; Mills, IW, 2011) |
| "To assess the efficacy and safety of pregabalin alone or in combination with tolterodine extended release (ER) in subjects with idiopathic OAB." | 2.76 | Investigation of the clinical efficacy and safety of pregabalin alone or combined with tolterodine in female subjects with idiopathic overactive bladder. ( Cossons, NH; Darekar, A; Marencak, J; Mills, IW, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chua, ME | 1 |
| See, MC | 1 |
| Esmeňa, EB | 1 |
| Balingit, JC | 1 |
| Morales, ML | 1 |
| Marencak, J | 1 |
| Cossons, NH | 1 |
| Darekar, A | 1 |
| Mills, IW | 1 |
| Ansari, MS | 1 |
| Bharti, A | 1 |
| Kumar, R | 1 |
| Ranjan, P | 1 |
| Srivastava, A | 1 |
| Kapoor, R | 1 |
| Loutochin, O | 1 |
| Al Afraa, T | 1 |
| Campeau, L | 1 |
| Mahfouz, W | 1 |
| Elzayat, E | 1 |
| Corcos, J | 1 |
| Vignes, JR | 1 |
| Deloire, MS | 1 |
| Petry, KG | 1 |
| Nagy, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of Gabapentin in Treating Overactive Bladder[NCT01486706] | Phase 2/Phase 3 | 94 participants (Actual) | Interventional | 2010-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for gamma-aminobutyric acid and Bladder, Overactive
| Article | Year |
|---|---|
Efficacy and Safety of Gabapentin in Comparison to Solifenacin Succinate in Adult Overactive Bladder Treatment.
Topics: Adolescent; Adult; Aged; Amines; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Administrati | 2018 |
Investigation of the clinical efficacy and safety of pregabalin alone or combined with tolterodine in female subjects with idiopathic overactive bladder.
Topics: Adult; Aged; Analgesics; Benzhydryl Compounds; Cresols; Cross-Over Studies; Dose-Response Relationsh | 2011 |
Gabapentin: a novel drug as add-on therapy in cases of refractory overactive bladder in children.
Topics: Adolescent; Amines; Anticonvulsants; Child; Child, Preschool; Cholinergic Antagonists; Cyclohexaneca | 2013 |
2 other studies available for gamma-aminobutyric acid and Bladder, Overactive
| Article | Year |
|---|---|
Effect of the anticonvulsant medications pregabalin and lamotrigine on urodynamic parameters in an animal model of neurogenic detrusor overactivity.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Female; gamma-Am | 2012 |
Characterization and restoration of altered inhibitory and excitatory control of micturition reflex in experimental autoimmune encephalomyelitis in rats.
Topics: Animals; Baclofen; Bicuculline; Cauda Equina; Efferent Pathways; Electric Stimulation; Encephalomyel | 2007 |