Page last updated: 2024-10-16

gamma-aminobutyric acid and Bladder, Overactive

gamma-aminobutyric acid has been researched along with Bladder, Overactive in 5 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Research Excerpts

ExcerptRelevanceReference
"Gabapentin treatment with acceptable safety profile, improves OAB symptoms and HRQOL domains."2.87Efficacy and Safety of Gabapentin in Comparison to Solifenacin Succinate in Adult Overactive Bladder Treatment. ( Balingit, JC; Chua, ME; Esmeňa, EB; Morales, ML; See, MC, 2018)
" Adverse event were monitored and summarized."2.87Efficacy and Safety of Gabapentin in Comparison to Solifenacin Succinate in Adult Overactive Bladder Treatment. ( Balingit, JC; Chua, ME; Esmeňa, EB; Morales, ML; See, MC, 2018)
"Gabapentin was prescribed as an add-on therapy."2.78Gabapentin: a novel drug as add-on therapy in cases of refractory overactive bladder in children. ( Ansari, MS; Bharti, A; Kapoor, R; Kumar, R; Ranjan, P; Srivastava, A, 2013)
" Treatments were generally well tolerated; discontinuation rates due to adverse events were 4%, 2%, 5%, 0%, and 1% with standard- and low-dose pregabalin/tolterodine ER, pregabalin, tolterodine ER, and placebo, respectively."2.76Investigation of the clinical efficacy and safety of pregabalin alone or combined with tolterodine in female subjects with idiopathic overactive bladder. ( Cossons, NH; Darekar, A; Marencak, J; Mills, IW, 2011)
"To assess the efficacy and safety of pregabalin alone or in combination with tolterodine extended release (ER) in subjects with idiopathic OAB."2.76Investigation of the clinical efficacy and safety of pregabalin alone or combined with tolterodine in female subjects with idiopathic overactive bladder. ( Cossons, NH; Darekar, A; Marencak, J; Mills, IW, 2011)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chua, ME1
See, MC1
Esmeňa, EB1
Balingit, JC1
Morales, ML1
Marencak, J1
Cossons, NH1
Darekar, A1
Mills, IW1
Ansari, MS1
Bharti, A1
Kumar, R1
Ranjan, P1
Srivastava, A1
Kapoor, R1
Loutochin, O1
Al Afraa, T1
Campeau, L1
Mahfouz, W1
Elzayat, E1
Corcos, J1
Vignes, JR1
Deloire, MS1
Petry, KG1
Nagy, F1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy and Safety of Gabapentin in Treating Overactive Bladder[NCT01486706]Phase 2/Phase 394 participants (Actual)Interventional2010-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for gamma-aminobutyric acid and Bladder, Overactive

ArticleYear
Efficacy and Safety of Gabapentin in Comparison to Solifenacin Succinate in Adult Overactive Bladder Treatment.
    Lower urinary tract symptoms, 2018, Volume: 10, Issue:2

    Topics: Adolescent; Adult; Aged; Amines; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Administrati

2018
Investigation of the clinical efficacy and safety of pregabalin alone or combined with tolterodine in female subjects with idiopathic overactive bladder.
    Neurourology and urodynamics, 2011, Volume: 30, Issue:1

    Topics: Adult; Aged; Analgesics; Benzhydryl Compounds; Cresols; Cross-Over Studies; Dose-Response Relationsh

2011
Gabapentin: a novel drug as add-on therapy in cases of refractory overactive bladder in children.
    Journal of pediatric urology, 2013, Volume: 9, Issue:1

    Topics: Adolescent; Amines; Anticonvulsants; Child; Child, Preschool; Cholinergic Antagonists; Cyclohexaneca

2013

Other Studies

2 other studies available for gamma-aminobutyric acid and Bladder, Overactive

ArticleYear
Effect of the anticonvulsant medications pregabalin and lamotrigine on urodynamic parameters in an animal model of neurogenic detrusor overactivity.
    Neurourology and urodynamics, 2012, Volume: 31, Issue:7

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Female; gamma-Am

2012
Characterization and restoration of altered inhibitory and excitatory control of micturition reflex in experimental autoimmune encephalomyelitis in rats.
    The Journal of physiology, 2007, Jan-15, Volume: 578, Issue:Pt 2

    Topics: Animals; Baclofen; Bicuculline; Cauda Equina; Efferent Pathways; Electric Stimulation; Encephalomyel

2007