gamma-aminobutyric acid has been researched along with Benign Psychomotor Epilepsy, Childhood in 182 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study evaluated the distribution pattern of GABAergic interneurons, especially parvalbumin (PV)- and somatostatin (SS)-immunopositive neurons, and excitatory propagation pattern in the IC of rats 4-7 days and 2 months after pilocarpine-induced status epilepticus (4-7 d and 2 m post-SE rats, respectively)." | 7.76 | Pilocarpine-induced status epilepticus causes acute interneuron loss and hyper-excitatory propagation in rat insular cortex. ( Chen, S; Fujita, S; Kobayashi, M; Koshikawa, N, 2010) |
| "Several similarities exist between the alterations observed in the chronic pilocarpine model of recurrent seizures in the rat and those found in human temporal lobe epilepsy." | 7.69 | Vulnerability and plasticity of the GABA system in the pilocarpine model of spontaneous recurrent seizures. ( Esclapez, M; Houser, CR, 1996) |
| "Vigabatrin (VGB) is a new antiepileptic drug that increases the human brain gamma-aminobutyric acid (GABA) level by irreversibly inhibiting GABA transaminase." | 6.70 | Effects of vigabatrin on brain GABA+/CR signals in patients with epilepsy monitored by 1H-NMR-spectroscopy: responder characteristics. ( Boesiger, P; Duc, CO; Meier, D; Mueller, SG; Russ, W; Weber, B; Weber, OM; Wieser, HG, 2001) |
| " The present study evaluated the distribution pattern of GABAergic interneurons, especially parvalbumin (PV)- and somatostatin (SS)-immunopositive neurons, and excitatory propagation pattern in the IC of rats 4-7 days and 2 months after pilocarpine-induced status epilepticus (4-7 d and 2 m post-SE rats, respectively)." | 3.76 | Pilocarpine-induced status epilepticus causes acute interneuron loss and hyper-excitatory propagation in rat insular cortex. ( Chen, S; Fujita, S; Kobayashi, M; Koshikawa, N, 2010) |
| " Stereological techniques were used to estimate numbers of gephyrin-positive punctae in the dentate gyrus, which were reduced short-term (5 days after pilocarpine-induced status epilepticus) but later rebounded beyond controls in epileptic rats." | 3.76 | Initial loss but later excess of GABAergic synapses with dentate granule cells in a rat model of temporal lobe epilepsy. ( Buckmaster, PS; Phanwar, I; Thind, KK; Wen, X; Yamawaki, R; Zhang, G, 2010) |
| "To determine whether a pharmacologic treatment could delay or prevent the epileptogenesis induced by status epilepticus (SE) through the protection of some brain areas, we studied the effects of the long-term exposure to pregabalin (PGB) on neuronal damage and epileptogenesis induced by lithium-pilocarpine SE." | 3.72 | Long-term pregabalin treatment protects basal cortices and delays the occurrence of spontaneous seizures in the lithium-pilocarpine model in the rat. ( André, V; Ferrandon, A; Koning, E; Nehlig, A; Rigoulot, MA, 2003) |
| " The second patient complained of impotence after a rash while taking phenytoin and carbamazepine." | 3.70 | Improved sexual function in three men taking lamotrigine for epilepsy. ( Carwile, ST; Husain, AM; Miller, PP; Radtke, RA, 2000) |
| "Several similarities exist between the alterations observed in the chronic pilocarpine model of recurrent seizures in the rat and those found in human temporal lobe epilepsy." | 3.69 | Vulnerability and plasticity of the GABA system in the pilocarpine model of spontaneous recurrent seizures. ( Esclapez, M; Houser, CR, 1996) |
| "Gamma-Aminobutyric acid (GABA) has been implicated in the neurochemistry of epilepsy." | 3.66 | Low cerebrospinal fluid gamma-aminobutyric acid content in seizure patients. ( Ballenger, JC; Glaeser, BS; Hare, TA; Post, RM; Wood, JH, 1979) |
| "Temporal lobe epilepsy was associated with bilateral reduction in NAAt/Cr but not significant abnormality in GABA+/Cr or GLX/Cr." | 2.74 | Proton MR spectroscopy of metabolite concentrations in temporal lobe epilepsy and effect of temporal lobe resection. ( Barker, GJ; Duncan, JS; McLean, MA; Simister, RJ, 2009) |
| "Vigabatrin (VGB) is a new antiepileptic drug that increases the human brain gamma-aminobutyric acid (GABA) level by irreversibly inhibiting GABA transaminase." | 2.70 | Effects of vigabatrin on brain GABA+/CR signals in patients with epilepsy monitored by 1H-NMR-spectroscopy: responder characteristics. ( Boesiger, P; Duc, CO; Meier, D; Mueller, SG; Russ, W; Weber, B; Weber, OM; Wieser, HG, 2001) |
| "Epilepsy is one of the most impactful diseases on social life." | 2.47 | Temporal lobe epilepsy and anti glutamic acid decarboxylase autoimmunity. ( Errichiello, L; Striano, P; Striano, S; Zara, F, 2011) |
| "Temporal lobe epilepsy is one of the most common forms of epilepsy." | 2.43 | Axonal sprouting of GABAergic interneurons in temporal lobe epilepsy. ( Bausch, SB, 2005) |
| "The characteristic clinical history, seizure semiology, and magnetic resonance imaging findings have allowed a discrete epilepsy syndrome to be established." | 2.41 | Adolescent seizures and epilepsy syndromes. ( Kim, HL; Wheless, JW, 2002) |
| "Knowledge of these syndromes has important treatment and prognostic implications, which usually extend into adulthood." | 2.41 | Adolescent seizures and epilepsy syndromes. ( Kim, HL; Wheless, JW, 2002) |
| "The events that follow epilepsy seizures are not restricted to the immediate period." | 2.41 | Cell death and synaptic reorganizations produced by seizures. ( Ben-Ari, Y, 2001) |
| " This may be related to dosage and speed of introduction." | 2.39 | Psychotic and severe behavioural reactions with vigabatrin: a review. ( Ferrie, CD; Panayiotopoulos, CP; Robinson, RO, 1996) |
| "Mean seizure class did not differ between the treatment groups." | 1.91 | E2730, an uncompetitive γ-aminobutyric acid transporter-1 inhibitor, suppresses epileptic seizures in a rat model of chronic mesial temporal lobe epilepsy. ( Ali, I; Brady, RD; Braine, E; Casillas-Espinosa, PM; Cheng, JY; Fukushima, K; Haskali, MB; Hudson, MR; Jones, NC; Jupp, B; Kwan, P; Major, B; Mychasiuk, R; O'Brien, TJ; Sachdev, P; Shultz, SR; Silva, J; Thergarajan, P; Vivash, L; Wright, DK; Yamakawa, GR, 2023) |
| "Secondary generalized seizure (sGS) is a major source of disability in temporal lobe epilepsy (TLE) with unclear cellular/circuit mechanisms." | 1.46 | Depolarized GABAergic Signaling in Subicular Microcircuits Mediates Generalized Seizure in Temporal Lobe Epilepsy. ( Chen, B; Chen, Z; Duan, S; Gao, F; Guo, Y; Ji, C; Li, X; Liang, J; Luo, J; Wang, S; Wang, Y; Wu, X; Xu, C; Xu, Z, 2017) |
| "Using a rat model of complex febrile seizures, which are thought to be a precipitating insult of TLE later in life, we report that aberrant migration of neonatal-generated granule cells results in granule cell ectopia that persists into adulthood." | 1.38 | GABAergic excitation after febrile seizures induces ectopic granule cells and adult epilepsy. ( Ichikawa, J; Ikegaya, Y; Koyama, R; Matsuki, N; Miyamoto, D; Muramatsu, R; Sasaki, T; Tao, K, 2012) |
| "Temporal lobe epilepsy is the most common type of epilepsy in adults, and its pathophysiology remains unclear." | 1.33 | Hyperexcitability, interneurons, and loss of GABAergic synapses in entorhinal cortex in a model of temporal lobe epilepsy. ( Buckmaster, PS; Kumar, SS, 2006) |
| "Temporal lobe epilepsy is the most common type of epilepsy in adults, and its underlying mechanisms are unclear." | 1.32 | Reduced inhibition and increased output of layer II neurons in the medial entorhinal cortex in a model of temporal lobe epilepsy. ( Buckmaster, PS; Kobayashi, M; Wen, X, 2003) |
| "Gabapentin (GBP) is a commonly used drug in the treatment of partial seizures, but its mode of action is still unclear." | 1.32 | Gabapentin increases the hyperpolarization-activated cation current Ih in rat CA1 pyramidal cells. ( Feuerstein, TJ; Freiman, TM; Surges, R, 2003) |
| "Lamotrigine was added to the carbamazepine regimen; impotence improved with decrease in carbamazepine and increase in lamotrigine." | 1.31 | Improved sexual function in three men taking lamotrigine for epilepsy. ( Carwile, ST; Husain, AM; Miller, PP; Radtke, RA, 2000) |
| " After lamotrigine was added for better seizure control and the dosage of gabapentin was tapered, anorgasmia improved." | 1.31 | Improved sexual function in three men taking lamotrigine for epilepsy. ( Carwile, ST; Husain, AM; Miller, PP; Radtke, RA, 2000) |
| "The second patient complained of impotence after a rash while taking phenytoin and carbamazepine." | 1.31 | Improved sexual function in three men taking lamotrigine for epilepsy. ( Carwile, ST; Husain, AM; Miller, PP; Radtke, RA, 2000) |
| "Mesial temporal lobe epilepsy is characterized by hippocampal atrophy, hypometabolism, and decreased N-acetylaspartate, often attributed to neuron loss and gliosis." | 1.31 | Neuronal and glial metabolite content of the epileptogenic human hippocampus. ( Errante, LD; Kim, JH; Petroff, OA; Rothman, DL; Spencer, DD, 2002) |
| "Temporal lobe epilepsy is known to be associated with hyperactivity that is likely to be generated or amplified in the hippocampal formation." | 1.31 | Preservation of perisomatic inhibitory input of granule cells in the epileptic human dentate gyrus. ( Borhegyi, Z; Eross, L; Freund, TF; Halász, P; Maglóczky, Z; Szabó, Z; Tóth, S; Wittner, L, 2001) |
| "Vigabatrin has been shown to protect against hippocampal neuronal cell death in experimental models of epilepsy." | 1.29 | Treatment with antiepileptic drugs: possible neuroprotective effects. ( Pitkänen, A, 1996) |
| "The creatine content was the same in biopsied epileptic cortex (8." | 1.29 | Symbiosis between in vivo and in vitro NMR spectroscopy: the creatine, N-acetylaspartate, glutamate, and GABA content of the epileptic human brain. ( Petroff, OA; Pleban, LA; Spencer, DD, 1995) |
| "A study was conducted to assess the impact of single dosing and different dosing intervals of vigabatrin [gamma vinyl GABA (GVG)] in 11 patients with drug-resistant complex partial seizures." | 1.28 | Pharmacokinetic effects of vigabatrin on cerebrospinal fluid amino acids in humans. ( Ben-Menachem, E, 1989) |
| "Gamma-Aminobutyric acid (GABA) has been implicated in the neurochemistry of epilepsy." | 1.26 | Low cerebrospinal fluid gamma-aminobutyric acid content in seizure patients. ( Ballenger, JC; Glaeser, BS; Hare, TA; Post, RM; Wood, JH, 1979) |
| "Although lumbar CSF GABA levels in our seizure patients did not significantly correlate with serum concentrations of phenytoin, phenobarbital, or primidone, additional study of medication-free epileptic patients may be required to evaluate the possibility of anticonvulsant-drug-induced CSF GABA alterations." | 1.26 | Low cerebrospinal fluid gamma-aminobutyric acid content in seizure patients. ( Ballenger, JC; Glaeser, BS; Hare, TA; Post, RM; Wood, JH, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (7.69) | 18.7374 |
| 1990's | 31 (17.03) | 18.2507 |
| 2000's | 83 (45.60) | 29.6817 |
| 2010's | 41 (22.53) | 24.3611 |
| 2020's | 13 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Gurrell, R | 1 |
| Iredale, P | 1 |
| Evrard, A | 1 |
| Duveau, V | 1 |
| Ruggiero, C | 1 |
| Roucard, C | 1 |
| Avoli, M | 6 |
| de Curtis, M | 2 |
| Lévesque, M | 1 |
| Librizzi, L | 1 |
| Uva, L | 1 |
| Wang, S | 3 |
| Stieve, BJ | 1 |
| Smith, MM | 1 |
| Krook-Magnuson, E | 1 |
| Ali, I | 1 |
| Silva, J | 1 |
| Casillas-Espinosa, PM | 1 |
| Braine, E | 1 |
| Yamakawa, GR | 1 |
| Hudson, MR | 1 |
| Brady, RD | 1 |
| Major, B | 1 |
| Thergarajan, P | 1 |
| Haskali, MB | 1 |
| Wright, DK | 1 |
| Jupp, B | 1 |
| Vivash, L | 1 |
| Shultz, SR | 1 |
| Mychasiuk, R | 1 |
| Kwan, P | 2 |
| Jones, NC | 1 |
| Fukushima, K | 1 |
| Sachdev, P | 1 |
| Cheng, JY | 1 |
| O'Brien, TJ | 2 |
| Ruffolo, G | 1 |
| Martinello, K | 2 |
| Labate, A | 1 |
| Cifelli, P | 1 |
| Fucile, S | 2 |
| Di Gennaro, G | 4 |
| Quattrone, A | 1 |
| Esposito, V | 6 |
| Limatola, C | 1 |
| Giangaspero, F | 3 |
| Aronica, E | 2 |
| Palma, E | 7 |
| Gambardella, A | 1 |
| Dai, Y | 1 |
| Song, Y | 2 |
| Xie, J | 1 |
| Xiao, G | 1 |
| Li, X | 2 |
| Li, Z | 2 |
| Gao, F | 2 |
| Zhang, Y | 1 |
| He, E | 1 |
| Xu, S | 1 |
| Wang, Y | 3 |
| Zheng, W | 1 |
| Jiang, X | 1 |
| Qi, Z | 1 |
| Meng, D | 1 |
| Fan, Z | 1 |
| Cai, X | 1 |
| Gonen, OM | 1 |
| Moffat, BA | 1 |
| Desmond, PM | 1 |
| Lui, E | 1 |
| Hamelin, S | 1 |
| Stupar, V | 1 |
| Mazière, L | 1 |
| Guo, J | 1 |
| Labriji, W | 1 |
| Liu, C | 1 |
| Bretagnolle, L | 1 |
| Parrot, S | 1 |
| Barbier, EL | 1 |
| Depaulis, A | 1 |
| Fauvelle, F | 1 |
| He, C | 1 |
| Liu, P | 1 |
| Wu, Y | 1 |
| Chen, H | 1 |
| Yin, J | 1 |
| Zhang, T | 1 |
| Yu, F | 1 |
| Xu, H | 1 |
| Chen, M | 1 |
| Chen, X | 1 |
| Guo, L | 1 |
| Zhou, C | 1 |
| Xu, Y | 1 |
| Wang, F | 1 |
| Yu, J | 1 |
| Wu, B | 1 |
| Lybrand, ZR | 1 |
| Goswami, S | 1 |
| Zhu, J | 1 |
| Jarzabek, V | 1 |
| Merlock, N | 1 |
| Aktar, M | 1 |
| Smith, C | 1 |
| Zhang, L | 1 |
| Varma, P | 1 |
| Cho, KO | 1 |
| Ge, S | 1 |
| Hsieh, J | 1 |
| Ren, E | 1 |
| Curia, G | 1 |
| Gu, Y | 1 |
| Wu, H | 1 |
| Wang, T | 1 |
| Yu, S | 1 |
| Han, Z | 1 |
| Zhang, W | 1 |
| Mu, L | 1 |
| Wang, H | 2 |
| Na, M | 1 |
| Lin, Z | 1 |
| Xu, C | 1 |
| Xu, Z | 1 |
| Ji, C | 1 |
| Liang, J | 1 |
| Chen, B | 1 |
| Wu, X | 1 |
| Guo, Y | 1 |
| Luo, J | 1 |
| Duan, S | 1 |
| Chen, Z | 2 |
| Androsova, G | 1 |
| Krause, R | 1 |
| Borghei, M | 1 |
| Wassenaar, M | 1 |
| Auce, P | 1 |
| Avbersek, A | 1 |
| Becker, F | 1 |
| Berghuis, B | 1 |
| Campbell, E | 1 |
| Coppola, A | 1 |
| Francis, B | 1 |
| Wolking, S | 1 |
| Cavalleri, GL | 1 |
| Craig, J | 1 |
| Delanty, N | 2 |
| Koeleman, BPC | 1 |
| Kunz, WS | 1 |
| Lerche, H | 1 |
| Marson, AG | 1 |
| Sander, JW | 1 |
| Sills, GJ | 1 |
| Striano, P | 2 |
| Zara, F | 2 |
| Sisodiya, SM | 1 |
| Depondt, C | 1 |
| Subramanian, D | 1 |
| Pralong, E | 1 |
| Daniel, RT | 1 |
| Chacko, AG | 1 |
| Stoop, R | 1 |
| Babu, KS | 1 |
| Xu, K | 2 |
| Liu, Z | 1 |
| Wang, L | 2 |
| Wu, G | 2 |
| Liu, T | 1 |
| Liu, F | 1 |
| Xu, W | 1 |
| Liu, J | 1 |
| Chen, S | 2 |
| Chun, E | 1 |
| Bumanglag, AV | 1 |
| Burke, SN | 1 |
| Sloviter, RS | 2 |
| Du, R | 1 |
| Zhu, X | 1 |
| Wu, S | 1 |
| Zhang, X | 1 |
| He, Y | 1 |
| Zhang, K | 1 |
| He, X | 1 |
| Wang, X | 1 |
| Sun, Y | 1 |
| Wang, Q | 1 |
| Zhang, H | 1 |
| Tian, M | 1 |
| Li, ZX | 1 |
| Yu, HM | 1 |
| Jiang, KW | 1 |
| Sun, C | 3 |
| Sun, J | 1 |
| Erisir, A | 2 |
| Kapur, J | 5 |
| Grosser, S | 1 |
| Queenan, BN | 1 |
| Lalchandani, RR | 1 |
| Vicini, S | 1 |
| Soukupová, M | 1 |
| Binaschi, A | 1 |
| Falcicchia, C | 1 |
| Zucchini, S | 1 |
| Roncon, P | 1 |
| Magri, E | 1 |
| Grandi, E | 1 |
| Simonato, M | 2 |
| Lee, H | 1 |
| Yun, S | 1 |
| Kim, IS | 1 |
| Lee, IS | 1 |
| Shin, JE | 1 |
| Park, SC | 1 |
| Kim, WJ | 1 |
| Park, KI | 1 |
| Grabenstatter, HL | 1 |
| Cogswell, M | 1 |
| Cruz Del Angel, Y | 1 |
| Carlsen, J | 1 |
| Gonzalez, MI | 1 |
| Raol, YH | 1 |
| Russek, SJ | 1 |
| Brooks-Kayal, AR | 1 |
| Eftekhari, S | 1 |
| Mehrabi, S | 1 |
| Soleimani, M | 1 |
| Hassanzadeh, G | 1 |
| Shahrokhi, A | 1 |
| Mostafavi, H | 1 |
| Hayat, P | 1 |
| Barati, M | 1 |
| Mehdizadeh, H | 1 |
| Rahmanzadeh, R | 1 |
| Hadjighassem, MR | 1 |
| Joghataei, MT | 1 |
| Nugent, AC | 1 |
| Martinez, A | 1 |
| D'Alfonso, A | 1 |
| Zarate, CA | 1 |
| Theodore, WH | 1 |
| Yutsudo, N | 1 |
| Kitagawa, H | 1 |
| Armstrong, C | 1 |
| Wang, J | 1 |
| Yeun Lee, S | 1 |
| Broderick, J | 1 |
| Bezaire, MJ | 1 |
| Lee, SH | 1 |
| Soltesz, I | 2 |
| You, Z | 1 |
| Li, M | 1 |
| Pang, L | 1 |
| Cheng, J | 1 |
| Bethmann, K | 1 |
| Fritschy, JM | 4 |
| Brandt, C | 1 |
| Löscher, W | 2 |
| Simister, RJ | 1 |
| McLean, MA | 1 |
| Barker, GJ | 1 |
| Duncan, JS | 3 |
| Eichler, SA | 1 |
| Kirischuk, S | 1 |
| Jüttner, R | 1 |
| Schaefermeier, PK | 1 |
| Schafermeier, PK | 1 |
| Legendre, P | 1 |
| Lehmann, TN | 2 |
| Gloveli, T | 1 |
| Grantyn, R | 1 |
| Meier, JC | 1 |
| Thompson, K | 1 |
| Teichgräber, LA | 1 |
| Meencke, HJ | 1 |
| Weiss, T | 1 |
| Nitsch, R | 2 |
| Deisz, RA | 1 |
| Crespo Pérez, L | 1 |
| Moreira Vicente, V | 1 |
| Cano Ruiz, A | 1 |
| Gobernado Serrano, JM | 1 |
| Cobo Ibañez, N | 1 |
| Milicua Salamero, JM | 1 |
| Wittner, L | 3 |
| Huberfeld, G | 2 |
| Clémenceau, S | 3 |
| Eross, L | 3 |
| Dezamis, E | 1 |
| Entz, L | 1 |
| Ulbert, I | 1 |
| Baulac, M | 3 |
| Freund, TF | 3 |
| Maglóczky, Z | 3 |
| Miles, R | 4 |
| Sperk, G | 3 |
| Drexel, M | 2 |
| Pirker, S | 2 |
| Kücker, S | 1 |
| Töllner, K | 1 |
| Piechotta, M | 1 |
| Gernert, M | 2 |
| Fujita, S | 1 |
| Koshikawa, N | 1 |
| Kobayashi, M | 2 |
| Thind, KK | 2 |
| Yamawaki, R | 3 |
| Phanwar, I | 1 |
| Zhang, G | 1 |
| Wen, X | 2 |
| Buckmaster, PS | 6 |
| Kim, YB | 1 |
| Ryu, JK | 1 |
| Lee, HJ | 1 |
| Lim, IJ | 1 |
| Park, D | 1 |
| Lee, MC | 1 |
| Kim, SU | 1 |
| Bortel, A | 1 |
| Longo, D | 1 |
| de Guzman, P | 2 |
| Dubeau, F | 1 |
| Biagini, G | 2 |
| Wyeth, MS | 1 |
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| Mody, I | 3 |
| Houser, CR | 5 |
| Rajasekaran, K | 2 |
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| Mtchedlishvilli, Z | 1 |
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| Konishi, H | 1 |
| Morino, M | 1 |
| Ohata, K | 1 |
| Kiyama, H | 1 |
| Huneau, C | 1 |
| Demont-Guignard, S | 1 |
| Benquet, P | 1 |
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| Wendling, F | 2 |
| Akakin, D | 1 |
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| Aker, R | 2 |
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| Errichiello, L | 1 |
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| Strasser, SS | 1 |
| Pifl, C | 1 |
| Marschalek, J | 1 |
| Ortler, M | 1 |
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| Ottersen, OP | 1 |
| Sonnewald, U | 1 |
| Malkov, AE | 1 |
| Popova, IY | 1 |
| Pernhorst, K | 1 |
| Raabe, A | 1 |
| Niehusmann, P | 1 |
| van Loo, KM | 1 |
| Grote, A | 1 |
| Hoffmann, P | 1 |
| Cichon, S | 1 |
| Sander, T | 1 |
| Schoch, S | 1 |
| Becker, AJ | 1 |
| Maisano, X | 1 |
| Litvina, E | 1 |
| Tagliatela, S | 1 |
| Aaron, GB | 1 |
| Grabel, LB | 1 |
| Naegele, JR | 1 |
| Pavlov, I | 1 |
| Walker, MC | 1 |
| Köhling, R | 2 |
| Koyama, R | 1 |
| Tao, K | 1 |
| Sasaki, T | 1 |
| Ichikawa, J | 1 |
| Miyamoto, D | 1 |
| Muramatsu, R | 1 |
| Matsuki, N | 1 |
| Ikegaya, Y | 1 |
| van der Hel, WS | 1 |
| van Eijsden, P | 1 |
| Bos, IW | 1 |
| de Graaf, RA | 1 |
| Behar, KL | 2 |
| van Nieuwenhuizen, O | 1 |
| de Graan, PN | 4 |
| Braun, KP | 1 |
| Sun, FJ | 1 |
| Guo, W | 1 |
| Zheng, DH | 1 |
| Zhang, CQ | 1 |
| Li, S | 1 |
| Liu, SY | 1 |
| Yin, Q | 1 |
| Yang, H | 1 |
| Shu, HF | 1 |
| Zhang, GF | 2 |
| Silva, AV | 1 |
| Sanabria, ER | 1 |
| Cavalheiro, EA | 1 |
| Spreafico, R | 2 |
| Petroff, OA | 3 |
| Errante, LD | 1 |
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| Kim, JH | 1 |
| Spencer, DD | 6 |
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| Trettel, F | 1 |
| Miledi, R | 5 |
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| Freiman, TM | 1 |
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| Klitgaard, H | 1 |
| Matagne, A | 1 |
| Grimee, R | 1 |
| Vanneste-Goemaere, J | 1 |
| Margineanu, DG | 1 |
| Neder, L | 1 |
| Valente, V | 1 |
| Carlotti, CG | 1 |
| Leite, JP | 2 |
| Assirati, JA | 2 |
| Paçó-Larson, ML | 1 |
| Moreira, JE | 1 |
| Thomas, PM | 3 |
| Phillips, JP | 3 |
| O'Connor, WT | 3 |
| Cohen, AS | 1 |
| Lin, DD | 2 |
| Quirk, GL | 1 |
| Coulter, DA | 3 |
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| Rigoulot, MA | 1 |
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| Esclapez, M | 6 |
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| Pitkänen, A | 4 |
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| GUERRERO-FIGUEROA, R | 1 |
| Le Duigou, C | 1 |
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| Heilman, J | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A 57-Week, Multicenter, Active-treatment, Open-label Extension Trial of CVL-865 as Adjunctive Therapy in Adults With Drug-Resistant Focal Onset Seizures[NCT04686786] | Phase 2 | 120 participants (Anticipated) | Interventional | 2020-12-08 | Enrolling by invitation | ||
| A Randomized, Double-blind, Placebo-controlled, Parallel Group, Multicenter Trial of CVL-865 as Adjunctive Therapy in Adults With Drug-Resistant Focal Onset Seizures (REALIZE Trial)[NCT04244175] | Phase 2 | 150 participants (Anticipated) | Interventional | 2020-01-27 | Recruiting | ||
| Quantitative MRI and GABA Spectroscopy to Localize the Epileptic Zone[NCT06057233] | 40 participants (Anticipated) | Observational | 2024-03-31 | Not yet recruiting | |||
| GABA/Glutamate Balance in Temporal Lobe Epilepsy With and Without Major Depression[NCT00931619] | 29 participants (Actual) | Observational | 2009-06-29 | Completed | |||
| The BrainDrugs-Epilepsy Study: A Prospective Open-label Cohort Precision Medicine Study in Epilepsy[NCT05450822] | 550 participants (Anticipated) | Observational | 2022-02-18 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
32 reviews available for gamma-aminobutyric acid and Benign Psychomotor Epilepsy, Childhood
| Article | Year |
|---|---|
GABA
Topics: Animals; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; gamma-Amino | 2022 |
Synaptic Reshaping and Neuronal Outcomes in the Temporal Lobe Epilepsy.
Topics: Animals; Astrocytes; Disease Susceptibility; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Gluta | 2021 |
Tonic GABA inhibition in hippocampal dentate granule cells: its regulation and function in temporal lobe epilepsies.
Topics: Animals; Cytoplasmic Granules; Dentate Gyrus; Epilepsy, Temporal Lobe; Excitatory Amino Acid Antagon | 2013 |
Transplantation of GABA-producing cells for seizure control in models of temporal lobe epilepsy.
Topics: Animals; Brain Tissue Transplantation; Disease Models, Animal; Epilepsy, Temporal Lobe; gamma-Aminob | 2009 |
[Anticonvulsant hypersensitivity syndrome: an entity to be remembered].
Topics: Adolescent; Amines; Anemia, Hemolytic; Anticonvulsants; Astrocytoma; Brain Neoplasms; Carbamazepine; | 2009 |
Neuronal plasticity in animal models and the epileptic human hippocampus.
Topics: Animals; Dentate Gyrus; Disease Models, Animal; Epilepsy; Epilepsy, Temporal Lobe; gamma-Aminobutyri | 2009 |
Temporal lobe epilepsy and anti glutamic acid decarboxylase autoimmunity.
Topics: Animals; Antibodies; Autoimmune Diseases; Autoimmunity; Epilepsy; Epilepsy, Temporal Lobe; gamma-Ami | 2011 |
GABAergic transmission in temporal lobe epilepsy: the role of neurosteroids.
Topics: Animals; Brain; Disease Models, Animal; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Humans; Ne | 2013 |
Tonic GABA(A) receptor-mediated signalling in temporal lobe epilepsy.
Topics: Animals; Electrophysiology; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Humans; Neural Inhibit | 2013 |
Does interictal synchronization influence ictogenesis?
Topics: Animals; Disease Models, Animal; Electroencephalography Phase Synchronization; Epilepsy, Temporal Lo | 2013 |
Mesial temporal lobe epilepsy: a pathological replay of developmental mechanisms?
Topics: Animals; Brain; Chlorides; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe; gamma-Aminobut | 2003 |
Dogma and dreams: experimental lessons for epilepsy mechanism chasers.
Topics: Adult; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Humans; Neural Inhibition; Synaptic Transmi | 2005 |
Axonal sprouting of GABAergic interneurons in temporal lobe epilepsy.
Topics: Axons; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Humans; Interneurons | 2005 |
Mechanisms regulating GABAergic inhibitory transmission in the basolateral amygdala: implications for epilepsy and anxiety disorders.
Topics: Adrenergic alpha-Agonists; Amygdala; Animals; Anticonvulsants; Anxiety Disorders; Depression; Dose-R | 2007 |
Cell therapy in models for temporal lobe epilepsy.
Topics: Acetylcholine; Adenosine; Animals; Cell Transplantation; Disease Models, Animal; Epilepsy, Temporal | 2007 |
Seizures beget seizures: the quest for GABA as a key player.
Topics: Animals; Epilepsy; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Hippocampus; Humans; Nerve Net; | 2006 |
[The neurochemical mechanisms of temporal lobe epilepsy: an update].
Topics: Animals; Calcium Channels; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Glutamic Acid; Humans; | 2007 |
[Relevance of basic research to clinical data: Good answers, wrong questions!].
Topics: Adult; Animals; Brain; Child; Child, Preschool; Epilepsy; Epilepsy, Temporal Lobe; gamma-Aminobutyri | 2008 |
Interictal schizophrenia-like psychoses in temporal lobe epilepsy.
Topics: Anticonvulsants; Brain; Carbamazepine; Electroencephalography; Epilepsy, Temporal Lobe; Functional L | 1983 |
Magnetic resonance spectroscopy.
Topics: Aspartic Acid; Brain; Creatinine; Epilepsy; Epilepsy, Complex Partial; Epilepsy, Temporal Lobe; gamm | 1996 |
Psychotic and severe behavioural reactions with vigabatrin: a review.
Topics: Adult; Anticonvulsants; Child; Contraindications; Dose-Response Relationship, Drug; Epilepsy; Epilep | 1996 |
Amygdala damage in experimental and human temporal lobe epilepsy.
Topics: Amygdala; Animals; Disease Models, Animal; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Humans; | 1998 |
1H MR spectroscopy in patients with mesial temporal epilepsy.
Topics: Aspartic Acid; Choline; Creatine; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Glutamic Acid; G | 1998 |
Chandelier cells and epilepsy.
Topics: Animals; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Humans; Interneurons; Models, Neurologica | 1999 |
What is GABAergic inhibition? How is it modified in epilepsy?
Topics: Animals; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Hippocampus; Humans; Interneurons; Models | 2000 |
Kainate, a double agent that generates seizures: two decades of progress.
Topics: Animals; Disease Models, Animal; Electric Conductivity; Epilepsy, Temporal Lobe; Excitatory Amino Ac | 2000 |
Pathophysiology of epilepsy.
Topics: Adult; Animals; Anticonvulsants; Autoimmune Diseases; Calcium; Catecholamines; Cell Movement; Child; | 2000 |
The process of epileptogenesis: a pathophysiological approach.
Topics: Animals; Disease Models, Animal; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Glutamic Acid; Hi | 2001 |
Cell death and synaptic reorganizations produced by seizures.
Topics: Animals; Cell Death; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Hippocampus; Humans; In Vitro | 2001 |
Adolescent seizures and epilepsy syndromes.
Topics: Adolescent; Age Factors; Brain; Child; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe; Es | 2002 |
Sodium valproate: a review of its pharmacological properties and therapeutic efficacy in epilepsy.
Topics: Administration, Oral; Adult; Animals; Anticonvulsants; Behavior; Blood Platelets; Child; Clinical Tr | 1977 |
Neuron-glia relationships in human and experimental epilepsy: a biochemical point of view.
Topics: Amino Acids; Animals; Biological Transport; Brain; Carbonic Anhydrases; Epilepsy; Epilepsy, Temporal | 1986 |
6 trials available for gamma-aminobutyric acid and Benign Psychomotor Epilepsy, Childhood
| Article | Year |
|---|---|
Proton MR spectroscopy of metabolite concentrations in temporal lobe epilepsy and effect of temporal lobe resection.
Topics: Adolescent; Adult; Aspartic Acid; Brain Chemistry; Brain Mapping; Carnosine; Creatine; Epilepsy, Tem | 2009 |
Elevated extracellular levels of glutamate, aspartate and gamma-aminobutyric acid within the intraoperative, spontaneously epileptiform human hippocampus.
Topics: Adult; Anesthesia, General; Aspartic Acid; Electroencephalography; Epilepsy, Temporal Lobe; Female; | 2003 |
Progabide as an add-on drug for epilepsy refractory to high dose antiepileptic drug therapy.
Topics: Adult; Aged; Anticonvulsants; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combinati | 1984 |
Effects of vigabatrin on brain GABA+/CR signals in patients with epilepsy monitored by 1H-NMR-spectroscopy: responder characteristics.
Topics: Adolescent; Adult; Anticonvulsants; Brain; Brain Chemistry; Carnosine; Creatine; Epilepsy; Epilepsy, | 2001 |
Sodium valproate: a review of its pharmacological properties and therapeutic efficacy in epilepsy.
Topics: Administration, Oral; Adult; Animals; Anticonvulsants; Behavior; Blood Platelets; Child; Clinical Tr | 1977 |
Preliminary observations on the activity of progabide, administered as monotherapy in complex partial seizures.
Topics: Adolescent; Adult; Clinical Trials as Topic; Drug Administration Schedule; Epilepsy, Temporal Lobe; | 1988 |
145 other studies available for gamma-aminobutyric acid and Benign Psychomotor Epilepsy, Childhood
| Article | Year |
|---|---|
Pronounced antiseizure activity of the subtype-selective GABA
Topics: Animals; Anticonvulsants; Diazepam; Disease Models, Animal; Drug Resistant Epilepsy; Electroencephal | 2022 |
Pronounced antiseizure activity of the subtype-selective GABA
Topics: Animals; Anticonvulsants; Diazepam; Disease Models, Animal; Drug Resistant Epilepsy; Electroencephal | 2022 |
Pronounced antiseizure activity of the subtype-selective GABA
Topics: Animals; Anticonvulsants; Diazepam; Disease Models, Animal; Drug Resistant Epilepsy; Electroencephal | 2022 |
Pronounced antiseizure activity of the subtype-selective GABA
Topics: Animals; Anticonvulsants; Diazepam; Disease Models, Animal; Drug Resistant Epilepsy; Electroencephal | 2022 |
LINCs Are Vulnerable to Epileptic Insult and Fail to Provide Seizure Control via On-Demand Activation.
Topics: Animals; Disease Models, Animal; Epilepsy; Epilepsy, Temporal Lobe; Female; gamma-Aminobutyric Acid; | 2023 |
E2730, an uncompetitive γ-aminobutyric acid transporter-1 inhibitor, suppresses epileptic seizures in a rat model of chronic mesial temporal lobe epilepsy.
Topics: Adult; Animals; Disease Models, Animal; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe; g | 2023 |
Modulation of GABAergic dysfunction due to SCN1A mutation linked to Hippocampal Sclerosis.
Topics: Adult; Anterior Temporal Lobectomy; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Hippocampus; H | 2020 |
CB1-Antibody Modified Liposomes for Targeted Modulation of Epileptiform Activities Synchronously Detected by Microelectrode Arrays.
Topics: Animals; Antibodies; Coordination Complexes; Disease Models, Animal; Epilepsy, Temporal Lobe; gamma- | 2020 |
Seven-tesla quantitative magnetic resonance spectroscopy of glutamate, γ-aminobutyric acid, and glutathione in the posterior cingulate cortex/precuneus in patients with epilepsy.
Topics: Adult; Aged; Case-Control Studies; Epilepsy; Epilepsy, Generalized; Epilepsy, Temporal Lobe; gamma-A | 2020 |
In vivo γ-aminobutyric acid increase as a biomarker of the epileptogenic zone: An unbiased metabolomics approach.
Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Electrophoresis, Capillary; Epileps | 2021 |
Gamma-aminobutyric acid (GABA) changes in the hippocampus and anterior cingulate cortex in patients with temporal lobe epilepsy.
Topics: Aspartic Acid; Choline; Creatine; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Gyrus Cinguli; H | 2021 |
Dysregulation of REV-ERBα impairs GABAergic function and promotes epileptic seizures in preclinical models.
Topics: Acute Disease; Animals; Basic-Leucine Zipper Transcription Factors; Chronic Disease; Disease Models, | 2021 |
A critical period of neuronal activity results in aberrant neurogenesis rewiring hippocampal circuitry in a mouse model of epilepsy.
Topics: Animals; Calcium; Clozapine; Disease Models, Animal; Electroencephalography; Epilepsy; Epilepsy, Tem | 2021 |
Profiling Analysis of Circular RNA and mRNA in Human Temporal Lobe Epilepsy with Hippocampal Sclerosis ILAE Type 1.
Topics: Centromere Protein A; Chloride Channels; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Gliosis; | 2022 |
Depolarized GABAergic Signaling in Subicular Microcircuits Mediates Generalized Seizure in Temporal Lobe Epilepsy.
Topics: Adolescent; Adult; Animals; Case-Control Studies; Disease Models, Animal; Electroencephalography; Ep | 2017 |
Comparative effectiveness of antiepileptic drugs in patients with mesial temporal lobe epilepsy with hippocampal sclerosis.
Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Ataxia; Benzodiazepines; Carbamazepine; Clobazam; | 2017 |
Gamma oscillatory activity in vitro: a model system to assess pathophysiological mechanisms of comorbidity between autism and epilepsy.
Topics: Animals; Autism Spectrum Disorder; Comorbidity; Electric Stimulation; Electroencephalography; Epilep | 2018 |
Influence of hippocampal low-frequency stimulation on GABA
Topics: Amygdala; Animals; Brain-Derived Neurotrophic Factor; Cyclic AMP Response Element Modulator; Disease | 2018 |
Transplanting GABAergic Neurons Differentiated from Neural Stem Cells into Hippocampus Inhibits Seizures and Epileptiform Discharges in Pilocarpine-Induced Temporal Lobe Epilepsy Model.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Drug Resistant Epilepsy; Electroencephalography; | 2019 |
Targeted hippocampal GABA neuron ablation by Stable Substance P-saporin causes hippocampal sclerosis and chronic epilepsy in rats.
Topics: Animals; Chronic Disease; Dentate Gyrus; Epilepsy, Temporal Lobe; GABAergic Neurons; gamma-Aminobuty | 2019 |
PET imaging of metabolic changes after neural stem cells and GABA progenitor cells transplantation in a rat model of temporal lobe epilepsy.
Topics: Animals; Cell Line; Electroencephalography; Electrophysiology; Epilepsy, Temporal Lobe; Fluorodeoxyg | 2019 |
Loss of cholecystokinin-containing terminals in temporal lobe epilepsy.
Topics: Animals; Cholecystokinin; Dentate Gyrus; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Inhibitor | 2014 |
Hilar somatostatin interneurons contribute to synchronized GABA activity in an in vitro epilepsy model.
Topics: 4-Aminopyridine; Action Potentials; Animals; Calcium; Epilepsy, Temporal Lobe; gamma-Aminobutyric Ac | 2014 |
Impairment of GABA release in the hippocampus at the time of the first spontaneous seizure in the pilocarpine model of temporal lobe epilepsy.
Topics: Animals; Calcium; Disease Models, Animal; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Hippocam | 2014 |
Human fetal brain-derived neural stem/progenitor cells grafted into the adult epileptic brain restrain seizures in rat models of temporal lobe epilepsy.
Topics: Analysis of Variance; Animals; Blotting, Western; Brain; Cell Differentiation; Chromatography, High | 2014 |
Effect of spontaneous seizures on GABAA receptor α4 subunit expression in an animal model of temporal lobe epilepsy.
Topics: Animals; Disease Models, Animal; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Pilocarpine; Rats | 2014 |
BDNF modifies hippocampal KCC2 and NKCC1 expression in a temporal lobe epilepsy model.
Topics: Animals; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Epilepsy, Temporal Lobe; gamma-A | 2014 |
The relationship between glucose metabolism, resting-state fMRI BOLD signal, and GABAA-binding potential: a preliminary study in healthy subjects and those with temporal lobe epilepsy.
Topics: Adult; Brain; Brain Mapping; Epilepsy, Temporal Lobe; Female; gamma-Aminobutyric Acid; Glucose; Glut | 2015 |
Involvement of chondroitin 6-sulfation in temporal lobe epilepsy.
Topics: Animals; Carbohydrate Sulfotransferases; Cerebral Cortex; Disease Models, Animal; Epilepsy, Temporal | 2015 |
Target-selectivity of parvalbumin-positive interneurons in layer II of medial entorhinal cortex in normal and epileptic animals.
Topics: Animals; Calbindins; Cell Adhesion Molecules, Neuronal; Cholecystokinin; Disease Models, Animal; Ent | 2016 |
Protective Effect of Resveratrol on the Brain in a Rat Model of Epilepsy.
Topics: Animals; Anticonvulsants; CA1 Region, Hippocampal; Disease Models, Animal; Down-Regulation; Epilepsy | 2017 |
Antiepileptic drug resistant rats differ from drug responsive rats in GABA A receptor subunit expression in a model of temporal lobe epilepsy.
Topics: Animals; Anticonvulsants; Dentate Gyrus; Disease Models, Animal; Drug Resistance; Electric Stimulati | 2008 |
Glycinergic tonic inhibition of hippocampal neurons with depolarizing GABAergic transmission elicits histopathological signs of temporal lobe epilepsy.
Topics: Action Potentials; Adult; Animals; Calcium Signaling; Chlorides; Dendrites; Epilepsy, Temporal Lobe; | 2008 |
Impaired function of GABA(B) receptors in tissues from pharmacoresistant epilepsy patients.
Topics: Animals; Anticonvulsants; Baclofen; Bicuculline; Cerebral Cortex; Drug Resistance; Epilepsy; Epileps | 2009 |
The epileptic human hippocampal cornu ammonis 2 region generates spontaneous interictal-like activity in vitro.
Topics: Action Potentials; Adult; Animals; CA2 Region, Hippocampal; Cell Shape; Chlorides; Electrophysiology | 2009 |
Kindling as a model of temporal lobe epilepsy induces bilateral changes in spontaneous striatal activity.
Topics: Action Potentials; Amygdala; Animals; Corpus Striatum; Disease Models, Animal; Epilepsy, Temporal Lo | 2010 |
Pilocarpine-induced status epilepticus causes acute interneuron loss and hyper-excitatory propagation in rat insular cortex.
Topics: Animals; Biomarkers; Cell Count; Cerebral Cortex; Convulsants; Disease Models, Animal; Electric Stim | 2010 |
Initial loss but later excess of GABAergic synapses with dentate granule cells in a rat model of temporal lobe epilepsy.
Topics: Animals; Cell Count; Convulsants; Dendritic Spines; Dentate Gyrus; Disease Models, Animal; Epilepsy, | 2010 |
Midkine, heparin-binding growth factor, blocks kainic acid-induced seizure and neuronal cell death in mouse hippocampus.
Topics: Animals; Anticonvulsants; Astrocytes; Biomarkers; Cell Death; Cytokines; Disease Models, Animal; Epi | 2010 |
Selective changes in inhibition as determinants for limited hyperexcitability in the insular cortex of epileptic rats.
Topics: Action Potentials; Animals; Disease Models, Animal; Electrophysiology; Epilepsy, Temporal Lobe; gamm | 2010 |
Selective reduction of cholecystokinin-positive basket cell innervation in a model of temporal lobe epilepsy.
Topics: Animals; CA1 Region, Hippocampal; Cholecystokinin; Disease Models, Animal; Epilepsy, Temporal Lobe; | 2010 |
Receptors with low affinity for neurosteroids and GABA contribute to tonic inhibition of granule cells in epileptic animals.
Topics: Action Potentials; Affinity Labels; Animals; Blotting, Western; Dentate Gyrus; Disease Models, Anima | 2010 |
Pancreatitis-associated protein-I and pancreatitis-associated protein-III expression in a rat model of kainic acid-induced seizure.
Topics: Aminopeptidases; Animals; Antigens, Neoplasm; Biomarkers, Tumor; Disease Models, Animal; Epilepsy, T | 2011 |
Time-domain features of epileptic spikes as potential bio-markers of the epileptogenesis process.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biomarkers; Co | 2010 |
Ultrastructural GABA immunocytochemistry in the mossy fiber terminals of Wistar and genetic absence epileptic rats receiving amygdaloid kindling stimulations.
Topics: Amygdala; Animals; Dentate Gyrus; Disease Models, Animal; Epilepsy, Absence; Epilepsy, Temporal Lobe | 2011 |
Increased GABAergic inhibition in the midline thalamus affects signaling and seizure spread in the hippocampus-prefrontal cortex pathway.
Topics: Animals; Electric Stimulation; Electroencephalography; Epilepsy, Temporal Lobe; Evoked Potentials; G | 2011 |
Glutamate decarboxylase 67 is expressed in hippocampal mossy fibers of temporal lobe epilepsy patients.
Topics: Adolescent; Adult; Aged; Animals; Child; Dentate Gyrus; Dynorphins; Epilepsy, Temporal Lobe; Female; | 2012 |
Reduced astrocytic contribution to the turnover of glutamate, glutamine, and GABA characterizes the latent phase in the kainate model of temporal lobe epilepsy.
Topics: Amino Acids; Animals; Astrocytes; Carbon Isotopes; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; | 2011 |
Functional changes in the septal GABAergic system of animals with a model of temporal lobe epilepsy.
Topics: Animals; Brain; Disease Models, Animal; Electrophysiology; Epilepsy, Temporal Lobe; gamma-Aminobutyr | 2011 |
Promoter variants determine γ-aminobutyric acid homeostasis-related gene transcription in human epileptic hippocampi.
Topics: Alleles; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Genotype; Hippocampus; Humans; Polymorphi | 2011 |
Differentiation and functional incorporation of embryonic stem cell-derived GABAergic interneurons in the dentate gyrus of mice with temporal lobe epilepsy.
Topics: Animals; Cell Line; Dentate Gyrus; Disease Models, Animal; Embryonic Stem Cells; Epilepsy, Temporal | 2012 |
GABAergic excitation after febrile seizures induces ectopic granule cells and adult epilepsy.
Topics: Animals; Animals, Suckling; Brain Diseases; Bumetanide; Cell Lineage; Cell Movement; Choristoma; Den | 2012 |
In vivo MRS and histochemistry of status epilepticus-induced hippocampal pathology in a juvenile model of temporal lobe epilepsy.
Topics: Animals; Biomarkers; Choline; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Glutamine; Hippocamp | 2013 |
Increased expression of TRPV1 in the cortex and hippocampus from patients with mesial temporal lobe epilepsy.
Topics: Adolescent; Adult; Astrocytes; Case-Control Studies; Cerebral Cortex; Dendrites; Epilepsy, Temporal | 2013 |
Axon sprouting in a model of temporal lobe epilepsy creates a predominantly excitatory feedback circuit.
Topics: Animals; Atropine Derivatives; Axons; Dendrites; Disease Models, Animal; Epilepsy, Temporal Lobe; Fe | 2002 |
Alterations of the neocortical GABAergic system in the pilocarpine model of temporal lobe epilepsy: neuronal damage and immunocytochemical changes in chronic epileptic rats.
Topics: Animals; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Immunohistochemistry; Male; Neocortex; Ne | 2002 |
Neuronal and glial metabolite content of the epileptogenic human hippocampus.
Topics: Adult; Amino Acids; Aspartic Acid; Epilepsy, Temporal Lobe; Female; gamma-Aminobutyric Acid; Glutami | 2002 |
Expression of human epileptic temporal lobe neurotransmitter receptors in Xenopus oocytes: An innovative approach to study epilepsy.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adolescent; Adult; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolep | 2002 |
Neuroscience. GABA becomes exciting.
Topics: Action Potentials; Animals; Brain; Chlorides; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Hipp | 2002 |
On the origin of interictal activity in human temporal lobe epilepsy in vitro.
Topics: Action Potentials; Adult; Electroencephalography; Epilepsy, Temporal Lobe; Excitatory Amino Acid Ant | 2002 |
Gabapentin increases the hyperpolarization-activated cation current Ih in rat CA1 pyramidal cells.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cations; Cyclic AMP; Cyclohexanecarboxylic Acids; Dose-R | 2003 |
Electrophysiological, neurochemical and regional effects of levetiracetam in the rat pilocarpine model of temporal lobe epilepsy.
Topics: Animals; Anticonvulsants; Aspartic Acid; Clonazepam; Electroencephalography; Epilepsy, Temporal Lobe | 2003 |
Glutamate NMDA receptor subunit R1 and GAD mRNA expression in human temporal lobe epilepsy.
Topics: Adult; Epilepsy, Temporal Lobe; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hippocampu | 2002 |
Dentate granule cell GABA(A) receptors in epileptic hippocampus: enhanced synaptic efficacy and altered pharmacology.
Topics: Animals; Epilepsy, Temporal Lobe; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonist | 2003 |
Long-term pregabalin treatment protects basal cortices and delays the occurrence of spontaneous seizures in the lithium-pilocarpine model in the rat.
Topics: Animals; Anticonvulsants; Astrocytes; Brain; Cell Death; Cerebral Cortex; Convulsants; Electroenceph | 2003 |
Downregulation of the alpha5 subunit of the GABA(A) receptor in the pilocarpine model of temporal lobe epilepsy.
Topics: Animals; Disease Models, Animal; Down-Regulation; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; | 2003 |
Evidence for strychnine-sensitive glycine receptors in human amygdala.
Topics: Acetylcholine; Adult; Amygdala; Animals; Blotting, Western; Chromatography, High Pressure Liquid; Ep | 2003 |
Selective changes in gamma-aminobutyric acid type A receptor subunits in the hippocampus in spontaneously seizing rats with chronic temporal lobe epilepsy.
Topics: Animals; Chronic Disease; Disease Models, Animal; Epilepsy; Epilepsy, Temporal Lobe; gamma-Aminobuty | 2003 |
Reduced inhibition and increased output of layer II neurons in the medial entorhinal cortex in a model of temporal lobe epilepsy.
Topics: Animals; Dentate Gyrus; Disease Models, Animal; Entorhinal Cortex; Epilepsy, Temporal Lobe; gamma-Am | 2003 |
PSYCHOTIC BEHAVIOR WITH EVOKED SEPTAL DYSRHYTHMIA: EFFECTS OF INTRACEREBRAL ACETYLCHOLINE AND GAMMA AMINOBUTYRIC ACID.
Topics: Acetylcholine; Aminobutyrates; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe; gamma-Amin | 1965 |
Expression of plasma membrane GABA transporters but not of the vesicular GABA transporter in dentate granule cells after kainic acid seizures.
Topics: Animals; Carrier Proteins; Cell Membrane; Dentate Gyrus; Disease Models, Animal; Epilepsy; Epilepsy, | 2003 |
Hippocampal microdialysis during spontaneous intraoperative epileptiform activity.
Topics: Adult; Aspartic Acid; Dominance, Cerebral; Electroencephalography; Epilepsy, Temporal Lobe; Female; | 2004 |
Rapid deletion of mossy cells does not result in a hyperexcitable dentate gyrus: implications for epileptogenesis.
Topics: Dentate Gyrus; Disease Models, Animal; Electric Stimulation; Epilepsy, Temporal Lobe; Excitatory Pos | 2004 |
Evaluation of GABA system and cell damage in parahippocampus of patients with temporal lobe epilepsy showing antiepileptic effects after subacute electrical stimulation.
Topics: Adult; Cell Count; Electric Stimulation Therapy; Epilepsy, Temporal Lobe; Female; gamma-Aminobutyric | 2004 |
Synaptosomal glutamate and GABA transport in patients with temporal lobe epilepsy.
Topics: Amino Acid Transport System X-AG; Animals; Biological Transport; Calcium; Carrier Proteins; Epilepsy | 2004 |
Microdialysis of the lateral and medial temporal lobe during temporal lobe epilepsy surgery.
Topics: Action Potentials; Adult; Aspartic Acid; Electroencephalography; Epilepsy, Temporal Lobe; Extracellu | 2005 |
In vitro 1H NMR spectroscopy shows an increase in N-acetylaspartylglutamate and glutamine content in the hippocampus of amygdaloid-kindled rats.
Topics: Amino Acids; Amygdala; Animals; Creatine; Dipeptides; Disease Models, Animal; Energy Metabolism; Epi | 2005 |
Temporal patterns of fos expression in the dentate gyrus after spontaneous seizures in a mouse model of temporal lobe epilepsy.
Topics: Animals; Dentate Gyrus; Disease Models, Animal; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Hi | 2005 |
Rundown of GABA type A receptors is a dysfunction associated with human drug-resistant mesial temporal lobe epilepsy.
Topics: Adolescent; Adult; Aged; Animals; Anticonvulsants; Brain-Derived Neurotrophic Factor; Cell Membrane; | 2005 |
Altered inhibition in lateral amygdala networks in a rat model of temporal lobe epilepsy.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Amygdala; Animals; Disease Models, Animal; | 2006 |
Correlation of transcriptome profile with electrical activity in temporal lobe epilepsy.
Topics: Action Potentials; Adult; Down-Regulation; Electroencephalography; Epilepsy, Temporal Lobe; Female; | 2006 |
Distribution of GABAergic neurons in the striatum of amygdala-kindled rats: an immunohistochemical and in situ hybridization study.
Topics: Amygdala; Animals; Corpus Striatum; Disease Models, Animal; Epilepsy, Temporal Lobe; Female; gamma-A | 2006 |
Hyperexcitability, interneurons, and loss of GABAergic synapses in entorhinal cortex in a model of temporal lobe epilepsy.
Topics: Action Potentials; Animals; Cells, Cultured; Disease Models, Animal; Entorhinal Cortex; Epilepsy, Te | 2006 |
Anomalous levels of Cl- transporters in the hippocampal subiculum from temporal lobe epilepsy patients make GABA excitatory.
Topics: Animals; Bumetanide; Epilepsy, Temporal Lobe; Excitatory Postsynaptic Potentials; gamma-Aminobutyric | 2006 |
Subiculum network excitability is increased in a rodent model of temporal lobe epilepsy.
Topics: Action Potentials; Animals; Biomarkers; Convulsants; Disease Models, Animal; Electric Stimulation; E | 2006 |
The selective effects of somatostatin- and GABA-mediated transmissions on voltage gated Ca2+ channel immunoreactivity in the gerbil hippocampus.
Topics: Animals; Calcium Channels; Calcium Channels, L-Type; Calcium Channels, N-Type; Calcium Channels, P-T | 2006 |
Downregulation of tonic GABA currents following epileptogenic stimulation of rat hippocampal cultures.
Topics: Animals; Animals, Newborn; Benzothiadiazines; Cells, Cultured; Epilepsy, Temporal Lobe; Excitatory A | 2006 |
Dentate development in organotypic hippocampal slice cultures from p35 knockout mice.
Topics: Animals; Astrocytes; Axons; Cell Differentiation; Cell Movement; Dendrites; Dentate Gyrus; Epilepsy, | 2007 |
omega-Conotoxin MVIIA inhibits amygdaloid kindled seizures in Sprague-Dawley rats.
Topics: Amygdala; Animals; Anticonvulsants; Brain Stem; Calcium Channel Blockers; Calcium Channels, N-Type; | 2007 |
Distinct types of ionic modulation of GABA actions in pyramidal cells and interneurons during electrical induction of hippocampal seizure-like network activity.
Topics: Action Potentials; Animals; Cell Membrane; Chloride Channels; Chlorides; Epilepsy; Epilepsy, Tempora | 2007 |
The antiepileptic drug levetiracetam stabilizes the human epileptic GABAA receptors upon repetitive activation.
Topics: Adult; Aged; Animals; Anticonvulsants; Brain Tissue Transplantation; Cell Membrane; Child; Epilepsy, | 2007 |
Perturbed chloride homeostasis and GABAergic signaling in human temporal lobe epilepsy.
Topics: Adult; Animals; Chlorides; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Homeostasis; Humans; In | 2007 |
Diminished neurosteroid sensitivity of synaptic inhibition and altered location of the alpha4 subunit of GABA(A) receptors in an animal model of epilepsy.
Topics: Animals; Benzodiazepines; Disease Models, Animal; Drug Resistance; Epilepsy, Temporal Lobe; gamma-Am | 2007 |
Epileptiform synchronization in the rat insular and perirhinal cortices in vitro.
Topics: 4-Aminopyridine; Action Potentials; Animals; Cerebral Cortex; Cortical Synchronization; Epilepsy, Te | 2007 |
GABA(A)-current rundown of temporal lobe epilepsy is associated with repetitive activation of GABA(A) "phasic" receptors.
Topics: Animals; Electrophysiology; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Humans; Male; Neurons; | 2007 |
Downregulation of the CB1 cannabinoid receptor and related molecular elements of the endocannabinoid system in epileptic human hippocampus.
Topics: Adult; Age Factors; Aged; Analysis of Variance; Cannabinoid Receptor Modulators; Carrier Proteins; C | 2008 |
Decreased hippocampal volume on MRI is associated with increased extracellular glutamate in epilepsy patients.
Topics: Adolescent; Adult; Atrophy; Chromatography, High Pressure Liquid; Electroencephalography; Epilepsy, | 2008 |
Synaptic input to dentate granule cell basal dendrites in a rat model of temporal lobe epilepsy.
Topics: Animals; Cell Shape; Convulsants; Dendrites; Dentate Gyrus; Disease Models, Animal; Epilepsy, Tempor | 2008 |
Loss of GABAergic neurons in the subiculum and its functional implications in temporal lobe epilepsy.
Topics: Animals; Biomarkers; Dendrites; Electroencephalography; Epilepsy, Temporal Lobe; gamma-Aminobutyric | 2008 |
Kindling: an animal model of complex partial epilepsy.
Topics: Amygdala; Animals; Brain; Disease Models, Animal; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; | 1984 |
Prolonged GABA responses in dentate granule cells in slices isolated from patients with temporal lobe sclerosis.
Topics: Action Potentials; Bicuculline; Dentate Gyrus; Electrophysiology; Epilepsy, Temporal Lobe; GABA Anta | 1995 |
Hippocampal GABA transporter function in temporal-lobe epilepsy.
Topics: Amygdala; Animals; Carrier Proteins; Disease Models, Animal; Epilepsy, Temporal Lobe; GABA Plasma Me | 1995 |
Analysis of macromolecule resonances in 1H NMR spectra of human brain.
Topics: Adult; Creatine; Cytosol; Epilepsy, Temporal Lobe; Female; gamma-Aminobutyric Acid; Glutamic Acid; G | 1994 |
1H magnetic resonance spectroscopy of extracts of human epileptic neocortex and hippocampus.
Topics: Adolescent; Adult; Amino Acids; Aspartic Acid; Cerebral Cortex; Child; Epilepsy, Temporal Lobe; Fema | 1993 |
Zinc-induced collapse of augmented inhibition by GABA in a temporal lobe epilepsy model.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Chlorides; Dentate Gyrus | 1996 |
Treatment with antiepileptic drugs: possible neuroprotective effects.
Topics: Animals; Anticonvulsants; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Hippocampus; Humans; Ner | 1996 |
Symbiosis between in vivo and in vitro NMR spectroscopy: the creatine, N-acetylaspartate, glutamate, and GABA content of the epileptic human brain.
Topics: Aspartic Acid; Astrocytes; Biopsy; Creatine; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Gluta | 1995 |
Vigabatrin overdose.
Topics: Adult; Anticonvulsants; Combined Modality Therapy; Drug Overdose; Epilepsy, Temporal Lobe; Female; g | 1996 |
Vulnerability and plasticity of the GABA system in the pilocarpine model of spontaneous recurrent seizures.
Topics: Animals; Antibodies, Monoclonal; Dentate Gyrus; Disease Models, Animal; Epilepsy, Temporal Lobe; gam | 1996 |
Changes in hippocampal circuitry after pilocarpine-induced seizures as revealed by opioid receptor distribution and activation.
Topics: Animals; Dentate Gyrus; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Male; Neural Pathways; Pil | 1997 |
Differential epilepsy-associated alterations in postsynaptic GABA(A) receptor function in dentate granule and CA1 neurons.
Topics: Animals; Clonazepam; Epilepsy, Temporal Lobe; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampu | 1997 |
Vigabatrin versus carbamazepine and phenytoin in kainic acid-treated pubescent rats.
Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Enzyme Inhi | 1997 |
Effects of phenytoin, carbamazepine, and gabapentin on calcium channels in hippocampal granule cells from patients with temporal lobe epilepsy.
Topics: Acetates; Adult; Amines; Anticonvulsants; Calcium Channels; Carbamazepine; Cyclohexanecarboxylic Aci | 1998 |
Antiepileptic effects of tiagabine, a selective GABA uptake inhibitor, in the rat kindling model of temporal lobe epilepsy.
Topics: Amygdala; Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Dose-Response Relationship, Dru | 1997 |
GABA(A) receptor function in epileptic human dentate granule cells: comparison to epileptic and control rat.
Topics: Animals; Dentate Gyrus; Epilepsy, Temporal Lobe; GABA Agonists; GABA Antagonists; gamma-Aminobutyric | 1998 |
[Drug-resistant epilepsy].
Topics: Adult; Anticonvulsants; Brain Neoplasms; Calcinosis; Carbamazepine; Diagnosis, Differential; Drug Re | 1998 |
Hippocampal GABA and glutamate transporter immunoreactivity in patients with temporal lobe epilepsy.
Topics: Adolescent; Adult; Aged; Amino Acid Transport System X-AG; ATP-Binding Cassette Transporters; Child; | 1999 |
GABAergic neurons and GABA(A)-receptors in temporal lobe epilepsy.
Topics: Animals; Dentate Gyrus; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Hippocampus; Immunoenzyme | 1999 |
Characterization of neocortical and hippocampal synaptosomes from temporal lobe epilepsy patients.
Topics: Adult; Animals; Brain Neoplasms; Calcium; Epilepsy, Temporal Lobe; Female; gamma-Aminobutyric Acid; | 1999 |
Up-regulation of GAD65 and GAD67 in remaining hippocampal GABA neurons in a model of temporal lobe epilepsy.
Topics: Animals; Disease Models, Animal; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Gene Expression R | 1999 |
Deficit of quantal release of GABA in experimental models of temporal lobe epilepsy.
Topics: Animals; Electric Conductivity; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; gamma-Amino | 1999 |
Do GABAergic circuitries play a critical role in the regulation of seizure-induced neuronal damage and synaptic reorganization in the rat hippocampus?
Topics: Afferent Pathways; Animals; Brain Chemistry; Cell Survival; Denervation; Epilepsy, Temporal Lobe; Ex | 1999 |
Improved sexual function in three men taking lamotrigine for epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsies, Partial; | 2000 |
Glutamate and gamma-aminobutyric acid content and release of synaptosomes from temporal lobe epilepsy patients.
Topics: Animals; Calcium; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Huma | 2000 |
Viral infection of developing GABAergic neurons in a model of hippocampal disinhibition.
Topics: Animals; Central Nervous System Viral Diseases; Dentate Gyrus; Disease Models, Animal; Epilepsy, Tem | 2000 |
Inhibitory circuits in human dysplastic tissue.
Topics: Adult; Cerebral Cortex; Epilepsy, Temporal Lobe; Female; gamma-Aminobutyric Acid; Humans; Immunohist | 2000 |
Dendritic but not somatic GABAergic inhibition is decreased in experimental epilepsy.
Topics: Action Potentials; Animals; Calbindins; Dendrites; Epilepsy, Temporal Lobe; Excitatory Amino Acid An | 2001 |
GABA(B) receptor autoradiography in hippocampal sclerosis associated with human temporal lobe epilepsy.
Topics: Adult; Autoradiography; Cell Count; Epilepsy, Temporal Lobe; Female; gamma-Aminobutyric Acid; Hippoc | 2001 |
Alterations in dystrophin and utrophin expression parallel the reorganization of GABAergic synapses in a mouse model of temporal lobe epilepsy.
Topics: Animals; Carrier Proteins; Cytoskeletal Proteins; Dentate Gyrus; Dystrophin; Epilepsy, Temporal Lobe | 2001 |
Alterations of hippocampal GAbaergic system contribute to development of spontaneous recurrent seizures in the rat lithium-pilocarpine model of temporal lobe epilepsy.
Topics: Animals; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Hippocampus; Interneurons; Lithium; Neuro | 2001 |
Diminished allopregnanolone enhancement of GABA(A) receptor currents in a rat model of chronic temporal lobe epilepsy.
Topics: Animals; Anticonvulsants; Chronic Disease; Diazepam; Electric Conductivity; Epilepsy, Temporal Lobe; | 2001 |
Preservation of perisomatic inhibitory input of granule cells in the epileptic human dentate gyrus.
Topics: Adolescent; Adult; Axons; Cortical Synchronization; Dendrites; Dentate Gyrus; Epilepsy, Temporal Lob | 2001 |
GABA and L-glutamic acid release in en bloc resection slices of human hippocampus: an in vitro microdialysis study.
Topics: Adult; Amygdala; Chromatography, High Pressure Liquid; Epilepsy, Temporal Lobe; Female; gamma-Aminob | 2001 |
Spontaneous recurrent seizures and neuropathology in the chronic phase of the pilocarpine and picrotoxin model epilepsy.
Topics: Acetylcholine; Action Potentials; Aggression; Animals; Behavior, Animal; Brain; Chronic Disease; Dis | 2002 |
Axon arbors and synaptic connections of a vulnerable population of interneurons in the dentate gyrus in vivo.
Topics: Action Potentials; Animals; Cell Death; Dentate Gyrus; Epilepsy, Temporal Lobe; Female; gamma-Aminob | 2002 |
Epileptic fast activity can be explained by a model of impaired GABAergic dendritic inhibition.
Topics: Action Potentials; Biological Clocks; Dendrites; Electroencephalography; Epilepsy, Temporal Lobe; ga | 2002 |
Recurrent complex partial status epilepticus associated with tiagabine rechallenge.
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Response | 2002 |
Low cerebrospinal fluid gamma-aminobutyric acid content in seizure patients.
Topics: Adult; Epilepsy; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; gamma-Aminobutyric Acid; H | 1979 |
Cerebrospinal fluid gamma-aminobutyric acid in neurologic disease.
Topics: Aminobutyrates; Cerebrovascular Disorders; Dementia; Epilepsy, Post-Traumatic; Epilepsy, Temporal Lo | 1976 |
The dentate gyrus as a regulated gate for the propagation of epileptiform activity.
Topics: Afferent Pathways; Animals; Brain Mapping; Culture Techniques; Dendrites; Epilepsy, Temporal Lobe; g | 1992 |
Synaptic connections of seizure-sensitive neurons in the dentate gyrus.
Topics: Animals; Brain Mapping; Calcium-Binding Proteins; Chlorocebus aethiops; Cholecystokinin; Cytoplasmic | 1992 |
Permanently altered hippocampal structure, excitability, and inhibition after experimental status epilepticus in the rat: the "dormant basket cell" hypothesis and its possible relevance to temporal lobe epilepsy.
Topics: Animals; Calbindins; Disease Models, Animal; Electric Stimulation; Epilepsy, Temporal Lobe; gamma-Am | 1991 |
A GABA and glutamate immunocytochemical study of cortical neurons of temporal epilepsy in humans.
Topics: Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Humans; Immunoenzyme Te | 1990 |
Pharmacokinetic effects of vigabatrin on cerebrospinal fluid amino acids in humans.
Topics: Adult; Amino Acids; Aminocaproates; Anticonvulsants; Cerebrospinal Fluid; Epilepsy, Temporal Lobe; F | 1989 |
Intracellular electrophysiology of CA1 pyramidal neurones in slices of the kainic acid lesioned hippocampus of the rat.
Topics: Adaptation, Physiological; Animals; Disease Models, Animal; Epilepsy, Temporal Lobe; Evoked Potentia | 1986 |
Anti-seizure and anti-epileptogenic effect of gamma-vinyl gamma-aminobutyric acid in amygdaloid kindling.
Topics: Aminocaproates; Amygdala; Animals; Anticonvulsants; Electrophysiology; Epilepsy, Temporal Lobe; gamm | 1986 |
Synaptic connections of axo-axonic (chandelier) cells in human epileptic temporal cortex.
Topics: Adolescent; Axons; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Humans; Male; Microscopy, Elect | 1986 |
Metabolic, morphologic and electrophysiologic profiles of human temporal lobe foci: an attempt at correlation.
Topics: Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Hippocampus; Humans; Neural Inhibition; Neuroglia; | 1986 |