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gamma-aminobutyric acid and Benign Cerebellar Neoplasms

gamma-aminobutyric acid has been researched along with Benign Cerebellar Neoplasms in 8 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Research Excerpts

ExcerptRelevanceReference
"A large case series of patients with centrally mediated pain, peripherally mediated pain, migraine, and tremor were treated in an open-label study with gabapentin (maximum of 2,700 mg/day)."9.08Gabapentin for treatment of pain and tremor: a large case series. ( Merren, MD, 1998)
"Gabapentin offers an effective, safe alternative therapy or co-therapy for the listed painful conditions and tremor; it does not affect the metabolism of other medications and is well tolerated."9.08Gabapentin for treatment of pain and tremor: a large case series. ( Merren, MD, 1998)
"A large case series of patients with centrally mediated pain, peripherally mediated pain, migraine, and tremor were treated in an open-label study with gabapentin (maximum of 2,700 mg/day)."5.08Gabapentin for treatment of pain and tremor: a large case series. ( Merren, MD, 1998)
"Gabapentin offers an effective, safe alternative therapy or co-therapy for the listed painful conditions and tremor; it does not affect the metabolism of other medications and is well tolerated."5.08Gabapentin for treatment of pain and tremor: a large case series. ( Merren, MD, 1998)
"Both patients suffered from refractory postoperative nausea and vomiting, treated with multiple traditional antiemetic drugs but without relief."1.42Gabapentin for Postoperative Vomiting in Children Requiring Posterior Fossa Tumor Resection. ( Fan, PC; Tsai, KC; Yang, YL, 2015)
"Chemical genomic profiling of QHii066-treated medulloblastoma cells confirmed inhibition of MYC-related transcriptional activity and revealed an enrichment of HOXA5 target gene expression."1.40α5-GABAA receptors negatively regulate MYC-amplified medulloblastoma growth. ( Amani, V; Archer, TC; Balansay, B; Cho, YJ; Cook, JM; Jensen, FE; Kosaras, B; Lechpammer, M; Lim, M; Mathios, D; Nguyen, B; Phallen, J; Pierre-Francois, J; Pomeroy, SL; Rallapalli, SK; Reimer, RJ; Schubert, S; Sengupta, S; Sun, H; Tang, Y; Teider, N; Tran, P; Weeraratne, SD; Yu, F, 2014)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's2 (25.00)18.2507
2000's2 (25.00)29.6817
2010's2 (25.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Martirosian, V1
Deshpande, K1
Zhou, H1
Shen, K1
Smith, K1
Northcott, P1
Lin, M1
Stepanosyan, V1
Das, D1
Remsik, J1
Isakov, D1
Boire, A1
De Feyter, H1
Hurth, K1
Li, S1
Wiemels, J1
Nakamura, B1
Shao, L1
Danilov, C1
Chen, T1
Neman, J1
Tsai, KC1
Yang, YL1
Fan, PC1
Sengupta, S1
Weeraratne, SD1
Sun, H1
Phallen, J1
Rallapalli, SK1
Teider, N1
Kosaras, B1
Amani, V1
Pierre-Francois, J1
Tang, Y1
Nguyen, B1
Yu, F1
Schubert, S1
Balansay, B1
Mathios, D1
Lechpammer, M1
Archer, TC1
Tran, P1
Reimer, RJ1
Cook, JM1
Lim, M1
Jensen, FE1
Pomeroy, SL1
Cho, YJ1
Dave, KA1
Bordey, A1
Syapin, PJ1
Salvaterra, PM1
Engelhardt, JK1
Florian, CL1
Pietsch, T2
Noble, M1
Williams, SR1
Merren, MD1
Codina, C1
Kraft, R1
Prinz, M1
Steinhäuser, C1
Cervós-Navarro, J1
Patt, S1

Reviews

1 review available for gamma-aminobutyric acid and Benign Cerebellar Neoplasms

ArticleYear
GABA increases Ca2+ in cerebellar granule cell precursors via depolarization: implications for proliferation.
    IUBMB life, 2009, Volume: 61, Issue:5

    Topics: Calcium; Cell Proliferation; Cells, Cultured; Cerebellar Neoplasms; Cerebellum; gamma-Aminobutyric A

2009

Trials

1 trial available for gamma-aminobutyric acid and Benign Cerebellar Neoplasms

ArticleYear
Gabapentin for treatment of pain and tremor: a large case series.
    Southern medical journal, 1998, Volume: 91, Issue:8

    Topics: Acetates; Adult; Aged; Amines; Analgesics; Anticonvulsants; Arachnoiditis; Cerebellar Neoplasms; Cyc

1998

Other Studies

6 other studies available for gamma-aminobutyric acid and Benign Cerebellar Neoplasms

ArticleYear
Medulloblastoma uses GABA transaminase to survive in the cerebrospinal fluid microenvironment and promote leptomeningeal dissemination.
    Cell reports, 2021, 06-29, Volume: 35, Issue:13

    Topics: 4-Aminobutyrate Transaminase; Acetylation; Animals; Cell Differentiation; Cell Line, Tumor; Cell Pro

2021
Gabapentin for Postoperative Vomiting in Children Requiring Posterior Fossa Tumor Resection.
    Pediatrics and neonatology, 2015, Volume: 56, Issue:5

    Topics: Amines; Cerebellar Neoplasms; Child; Child, Preschool; Craniotomy; Cyclohexanecarboxylic Acids; Exci

2015
α5-GABAA receptors negatively regulate MYC-amplified medulloblastoma growth.
    Acta neuropathologica, 2014, Volume: 127, Issue:4

    Topics: Animals; Benzodiazepines; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cerebellar Neoplasms; Ci

2014
Neuronal-like features of TE671 cells: presence of a functional nicotinic cholinergic receptor.
    Brain research, 1982, Jan-14, Volume: 231, Issue:2

    Topics: Acetylcholine; Action Potentials; Bungarotoxins; Cell Line; Cell Membrane; Cerebellar Neoplasms; gam

1982
Metabolic studies of human primitive neuroectodermal tumour cells by proton nuclear magnetic resonance spectroscopy.
    British journal of cancer, 1997, Volume: 75, Issue:7

    Topics: Aspartic Acid; Cerebellar Neoplasms; Cerebellum; Chromatography, High Pressure Liquid; gamma-Aminobu

1997
Voltage- and gamma-aminobutyric acid-activated membrane currents in the human medulloblastoma cell line MHH-MED-3.
    Neuroscience letters, 2000, Jun-16, Volume: 287, Issue:1

    Topics: Adolescent; Cell Membrane; Cerebellar Neoplasms; gamma-Aminobutyric Acid; Humans; Ion Channels; Male

2000