gamma-aminobutyric acid has been researched along with Basal Ganglia Diseases in 39 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Basal Ganglia Diseases: Diseases of the BASAL GANGLIA including the PUTAMEN; GLOBUS PALLIDUS; claustrum; AMYGDALA; and CAUDATE NUCLEUS. DYSKINESIAS (most notably involuntary movements and alterations of the rate of movement) represent the primary clinical manifestations of these disorders. Common etiologies include CEREBROVASCULAR DISORDERS; NEURODEGENERATIVE DISEASES; and CRANIOCEREBRAL TRAUMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The dichotomy of Parkinson's disease; akinesia with increased tone, and the mirror effects in Huntington's disease; hemiballismus and tardive dyskinesia, hyperkinesia with decreased tone are explained as due to two outputs of the system with an intervening inhibitory neuron which reverses the sign." | 2.36 | The basal ganglia in extrapyramidal dysfunction. ( Barnes, CD, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (71.79) | 18.7374 |
| 1990's | 4 (10.26) | 18.2507 |
| 2000's | 7 (17.95) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ferré, S | 1 |
| Quiroz, C | 1 |
| Woods, AS | 1 |
| Cunha, R | 1 |
| Popoli, P | 1 |
| Ciruela, F | 1 |
| Lluis, C | 1 |
| Franco, R | 1 |
| Azdad, K | 1 |
| Schiffmann, SN | 1 |
| Fedrowitz, M | 1 |
| Lindemann, S | 1 |
| Löscher, W | 2 |
| Gernert, M | 1 |
| Takakusaki, K | 1 |
| Habaguchi, T | 1 |
| Ohtinata-Sugimoto, J | 1 |
| Saitoh, K | 1 |
| Sakamoto, T | 1 |
| Di Giovanni, G | 1 |
| Di Matteo, V | 1 |
| Pierucci, M | 1 |
| Benigno, A | 1 |
| Esposito, E | 1 |
| Richards, AB | 1 |
| Scheel, TA | 1 |
| Wang, K | 1 |
| Henkemeyer, M | 1 |
| Kromer, LF | 1 |
| Lavoute, C | 1 |
| Weiss, M | 1 |
| Rostain, JC | 1 |
| Bunney, BS | 1 |
| Grace, AA | 1 |
| Hommer, DW | 1 |
| Bartholini, G | 2 |
| Lloyd, KG | 2 |
| Scheel-Krüger, J | 1 |
| Barnes, CD | 1 |
| DeFeudis, FV | 1 |
| Arushanian, EB | 1 |
| Dutov, AA | 1 |
| Rector, WG | 1 |
| Herlong, HF | 1 |
| Moses, H | 1 |
| Johnson, AE | 1 |
| Liminga, U | 1 |
| Lidén, A | 1 |
| Lindefors, N | 1 |
| Gunne, LM | 1 |
| Wiesel, FA | 1 |
| Lin, JJ | 1 |
| Chang, MK | 1 |
| Obeso, JA | 1 |
| Luquin, MR | 1 |
| Herrero, MT | 1 |
| Guridi, J | 1 |
| Zahniser, NR | 1 |
| Simosky, JK | 1 |
| Mayfield, RD | 1 |
| Negri, CA | 1 |
| Hanania, T | 1 |
| Larson, GA | 1 |
| Kelly, MA | 1 |
| Grandy, DK | 1 |
| Rubinstein, M | 1 |
| Low, MJ | 1 |
| Fredholm, BB | 1 |
| Cattabeni, F | 1 |
| Galli, CL | 1 |
| Groppetti, A | 1 |
| Racagni, G | 1 |
| Calne, DB | 1 |
| Eisler, T | 1 |
| Dray, A | 1 |
| Makeeva, VL | 1 |
| Linnoila, M | 1 |
| Viukari, M | 1 |
| Kietala, O | 1 |
| Wolfarth, S | 1 |
| Aizawa, H | 1 |
| Kwak, S | 1 |
| Shimizu, T | 1 |
| Mannen, T | 1 |
| Shibasaki, H | 1 |
| Kish, SJ | 1 |
| Chang, LJ | 1 |
| Mirchandani, L | 1 |
| Shannak, K | 1 |
| Hornykiewicz, O | 1 |
| Gerlach, J | 1 |
| Sandyk, R | 1 |
| Mukhin, EI | 1 |
| Schwarz, M | 1 |
| Turski, L | 1 |
| Sontag, KH | 1 |
| Snoek, JW | 1 |
| van Weerden, TW | 1 |
| Teelken, AW | 1 |
| van den Burg, W | 1 |
| Lakke, JP | 1 |
| Lipkin, PH | 1 |
| Roe, CR | 1 |
| Goodman, SI | 1 |
| Batshaw, ML | 1 |
| Smiałek, M | 2 |
| Królikiewicz-Sciborowska, H | 1 |
| Skrobisz, MD | 1 |
| Niemczewska-Syropolska, M | 1 |
| Sasinowska, M | 1 |
| Bugera-Piecuch, TE | 1 |
| Kosicka, B | 1 |
| Kittel, M | 1 |
| Gol'dblat, IuV | 1 |
| Lapin, IP | 1 |
| Dereux-Mortier, SA | 1 |
| Dereux, JF | 1 |
| Gallois, P | 1 |
| Mondrup, K | 1 |
| Dupont, E | 1 |
| Braendgaard, H | 1 |
| Soyka, D | 1 |
15 reviews available for gamma-aminobutyric acid and Basal Ganglia Diseases
| Article | Year |
|---|---|
An update on adenosine A2A-dopamine D2 receptor interactions: implications for the function of G protein-coupled receptors.
Topics: Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenylyl Cyclases; Animals; Basal | 2008 |
Serotonin involvement in the basal ganglia pathophysiology: could the 5-HT2C receptor be a new target for therapeutic strategies?
Topics: Animals; Basal Ganglia Diseases; Central Nervous System; gamma-Aminobutyric Acid; Humans; Movement D | 2006 |
Changing concepts of nigral dopamine system function within the basal ganglia: relevance to extrapyramidal disorders.
Topics: Antipsychotic Agents; Basal Ganglia; Basal Ganglia Diseases; Behavior; Dopamine; gamma-Aminobutyric | 1980 |
The potential of GABA-mimetics in the therapy of extrapyramidal disorders.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Dopamine; gamma-Aminobutyric Acid; Humans; Levodopa; N | 1980 |
GABA in the striatonigral and striatopallidal systems as moderator and mediator of striatal functions.
Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Catalepsy; Corpus Striatum; Diencephalon; gam | 1984 |
The basal ganglia in extrapyramidal dysfunction.
Topics: Basal Ganglia; Basal Ganglia Diseases; Corpus Striatum; Dyskinesia, Drug-Induced; Feedback; gamma-Am | 1983 |
GABA binding processes and behavior.
Topics: Aging; Animals; Basal Ganglia Diseases; Behavior; Behavior, Animal; Epilepsy; Extrapyramidal Tracts; | 1983 |
The neuropathology of GABA neurons in extrapyramidal disorders.
Topics: Basal Ganglia Diseases; gamma-Aminobutyric Acid; Humans; Huntington Disease; Neurons; Parkinson Dise | 1980 |
[Nigrostriatal system as a source of torsion extrapyramidal disorders (review)].
Topics: 5-Hydroxytryptophan; Acetylcholine; Animals; Basal Ganglia Diseases; Cats; Caudate Nucleus; Corpus S | 1980 |
Hemiballism-hemichorea and non-ketotic hyperglycaemia.
Topics: Aged; Basal Ganglia Diseases; Chorea; Dementia, Multi-Infarct; Diabetes Complications; Female; gamma | 1994 |
Significance of neurochemical parameters in the preclinical evaluation of neuroleptic drugs.
Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Brain Chemistry; Clozapine; Corpus Striatum; | 1979 |
The pathogensis and medical treatment of extrapyramidal disease.
Topics: Adult; Athetosis; Basal Ganglia Diseases; Caudate Nucleus; Chorea; Corpus Striatum; Dopamine; Dopami | 1979 |
The striatum and substantia nigra: a commentary on their relationships.
Topics: Basal Ganglia Diseases; Brain Mapping; Cerebral Cortex; Corpus Striatum; Dopamine; Electrophysiology | 1979 |
Experimental basis of the therapy of Parkinson's disease and the cholinergic-dopaminergic equilibrium in basal brain nuclei.
Topics: Animals; Apomorphine; Basal Ganglia Diseases; Behavior, Animal; Brain; Carbachol; Caudate Nucleus; C | 1976 |
The endogenous opioid system in neurological disorders of the basal ganglia.
Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Clonidine; Endorphins; gamma-Aminobutyric Aci | 1985 |
2 trials available for gamma-aminobutyric acid and Basal Ganglia Diseases
| Article | Year |
|---|---|
Effect of sodium valproate on tardive dyskinesia.
Topics: Age Factors; Aged; Basal Ganglia Diseases; Blood Coagulation; Central Nervous System; Clinical Trial | 1976 |
Meige syndrome: double-blind crossover study of sodium valproate.
Topics: Basal Ganglia Diseases; Double-Blind Method; Female; gamma-Aminobutyric Acid; Humans; Male; Meige Sy | 1987 |
22 other studies available for gamma-aminobutyric acid and Basal Ganglia Diseases
| Article | Year |
|---|---|
Altered spontaneous discharge rate and pattern of basal ganglia output neurons in the circling (ci2) rat mutant.
Topics: Action Potentials; Animals; Basal Ganglia; Basal Ganglia Diseases; Dopamine; Efferent Pathways; Fema | 2003 |
Basal ganglia efferents to the brainstem centers controlling postural muscle tone and locomotion: a new concept for understanding motor disorders in basal ganglia dysfunction.
Topics: Animals; Atropine; Basal Ganglia; Basal Ganglia Diseases; Bicuculline; Brain Stem; Cats; Choline O-A | 2003 |
EphB1 null mice exhibit neuronal loss in substantia nigra pars reticulata and spontaneous locomotor hyperactivity.
Topics: Animals; Basal Ganglia Diseases; beta-Galactosidase; Biomarkers; Cell Death; Cell Differentiation; C | 2007 |
Alterations in nigral NMDA and GABAA receptor control of the striatal dopamine level after repetitive exposures to nitrogen narcosis.
Topics: Air Pressure; Animals; Atmosphere Exposure Chambers; Basal Ganglia Diseases; Corpus Striatum; Diseas | 2008 |
Nonketotic hyperglycemia appearing as choreoathetosis or ballism.
Topics: Aged; Athetosis; Basal Ganglia Diseases; Chorea; Female; gamma-Aminobutyric Acid; Humans; Hyperglyce | 1982 |
Chronic treatment with a classical neuroleptic alters excitatory amino acid and GABAergic neurotransmission in specific regions of the rat brain.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Antipsychotic Agents; Autoradiogr | 1994 |
Origin of chorea-ballism and multisystem degeneration: pathophysiological implications.
Topics: Animals; Basal Ganglia Diseases; Chorea; Dopamine; Dystonia; gamma-Aminobutyric Acid; Globus Pallidu | 1993 |
Functional uncoupling of adenosine A(2A) receptors and reduced responseto caffeine in mice lacking dopamine D2 receptors.
Topics: Animals; Basal Ganglia Diseases; Caffeine; Cyclic AMP; Female; gamma-Aminobutyric Acid; Globus Palli | 2000 |
[Potential therapeutic activity of GABA-mimetic drugs in neuropsychiatry].
Topics: 4-Aminobutyrate Transaminase; Basal Ganglia Diseases; Bicuculline; Dopamine; Dyskinesia, Drug-Induce | 1979 |
[Neurologic adverse manifestations and complications of ambulatory therapy with psychotropic drugs in the late stages].
Topics: Adult; Aged; Antidepressive Agents; Autonomic Nervous System; Basal Ganglia Diseases; Cognition Diso | 1978 |
A case of adult onset pure pallidal degeneration. II. Analysis of neurotransmitter markers, with special reference to the termination of pallidothalamic tract in human brain.
Topics: Adult; Aged; Basal Ganglia Diseases; Biomarkers; Brain Chemistry; Choline O-Acetyltransferase; Femal | 1991 |
Progressive supranuclear palsy: relationship between extrapyramidal disturbances, dementia, and brain neurotransmitter markers.
Topics: Aged; Aspartic Acid; Basal Ganglia Diseases; Brain; Bulbar Palsy, Progressive; Choline O-Acetyltrans | 1985 |
Pathophysiological mechanisms underlying tardive dyskinesia.
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Brain; Dyskinesia, Drug-Induced; gamma-Aminobutyric Ac | 1985 |
[Neuropharmacologic analysis of compensatory processes after lesioning the head of the caudate nucleus].
Topics: Adaptation, Physiological; Animals; Basal Ganglia Diseases; Cats; Caudate Nucleus; Cholinergic Fiber | 1986 |
Disturbed GABAergic transmission in mutant Han-Wistar rats: further evidence for basal ganglia dysfunction.
Topics: Animals; Basal Ganglia Diseases; Bicuculline; Brain Chemistry; Electromyography; Female; gamma-Amino | 1985 |
A case of glutaric acidemia type I: effect of riboflavin and carnitine.
Topics: Amino Acid Metabolism, Inborn Errors; Basal Ganglia Diseases; Carnitine; Cerebral Palsy; Child, Pres | 1988 |
[Homovanillic acid (HVA) and gamma-aminobutyric acid (GABA) levels in the cerebrospinal fluid of patients with extrapyramidal syndromes].
Topics: Adult; Age Factors; Aged; Basal Ganglia Diseases; Female; gamma-Aminobutyric Acid; Homovanillic Acid | 1986 |
[GABA synthesis in the central nervous system of rats with extrapyramidal syndrome after acute cobalt acetate poisoning in cerebral ischemia].
Topics: Acetates; Acetic Acid; Acute Disease; Animals; Basal Ganglia Diseases; Brain; gamma-Aminobutyric Aci | 1987 |
[Phenibut potentiation of the therapeutic action of antiparkinson agents].
Topics: Adult; Aged; Antiparkinson Agents; Basal Ganglia Diseases; Drug Therapy, Combination; Follow-Up Stud | 1986 |
[Hemiballism caused by metastasis to Luys' body].
Topics: Adenocarcinoma; Aged; Basal Ganglia Diseases; Brain Neoplasms; Diencephalon; gamma-Aminobutyric Acid | 1985 |
Progabide in the treatment of hyperkinetic extrapyramidal movement disorders.
Topics: Adolescent; Adult; Aged; Athetosis; Basal Ganglia Diseases; Child; Chorea; Female; gamma-Aminobutyri | 1985 |
[Syndrome involving the extrapyramidal motor systems and their drug treatment].
Topics: Amantadine; Antiparkinson Agents; Basal Ganglia Diseases; Dihydroxyphenylalanine; gamma-Aminobutyric | 1974 |