gamma-aminobutyric acid has been researched along with Autism Spectrum Disorder in 86 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Autism Spectrum Disorder: Wide continuum of associated cognitive and neurobehavioral disorders, including, but not limited to, three core-defining features: impairments in socialization, impairments in verbal and nonverbal communication, and restricted and repetitive patterns of behaviors. (from DSM-V)
| Excerpt | Relevance | Reference |
|---|---|---|
| "With the current limited drug therapy for the core symptoms of autism spectrum disorder (ASD), we herein report a randomized, double-blind, placebo-controlled trial to investigate the efficacy, safety, and potential neural mechanism of bumetanide in children with ASD aged 3-6 years old." | 9.41 | Improved symptoms following bumetanide treatment in children aged 3-6 years with autism spectrum disorder: a randomized, double-blind, placebo-controlled trial. ( Dai, Y; Deng, S; Du, X; Feng, J; He, H; Ji, Y; Langley, C; Li, F; Li, WG; Liu, X; Luo, Q; Sahakian, BJ; Tang, Y; Wang, K; Yu, J; Zhang, J; Zhang, L; Zhou, X, 2021) |
| "Bumetanide has been reported to alter synaptic excitation-inhibition (E-I) balance by potentiating the action of γ-aminobutyric acid (GABA), thereby attenuating the severity of autism spectrum disorder (ASD) in animal models." | 9.34 | Symptom improvement in children with autism spectrum disorder following bumetanide administration is associated with decreased GABA/glutamate ratios. ( Dai, Y; Deng, S; Du, X; Feng, J; Huang, CC; Ji, Y; Li, F; Lin, CP; Luo, Q; Sahakian, BJ; Shen, C; Tang, Y; Wang, K; Xu, M; Yu, J; Zhang, L, 2020) |
| "There is increasing interest in the use of cannabis and its major non-intoxicating component cannabidiol (CBD) as a treatment for mental health and neurodevelopmental disorders, such as autism spectrum disorder (ASD)." | 9.30 | Effects of cannabidiol on brain excitation and inhibition systems; a randomised placebo-controlled single dose trial during magnetic resonance spectroscopy in adults with and without autism spectrum disorder. ( Ajram, L; Daly, E; Edden, RAE; Freyberg, J; Heasman, M; Horder, J; Ivin, G; Lythgoe, D; McAlonan, GM; Mendez, MA; Murphy, DGM; Pretzsch, CM; Voinescu, B; Wichers, R; Williams, S, 2019) |
| "Neurodevelopmental disorders (NDDs) including autism spectrum disorder (ASD), attention-deficit hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD) are thought to arise in part from the disruption in the excitatory/inhibitory balance of gamma-aminobutyric acid (GABA) and glutamate in the brain." | 8.31 | Cerebellar gamma-aminobutyric acid: Investigation of group effects in neurodevelopmental disorders. ( Anagnostou, E; Arnold, PD; Crosbie, J; Hammill, C; Lerch, JP; Near, J; Pang, EW; Schachar, R; Taylor, MJ, 2023) |
| "Bumetanide, a drug being studied in autism spectrum disorder (ASD) may act to restore gamma-aminobutyric acid (GABA) function, which may be modulated by the immune system." | 8.12 | The immuno-behavioural covariation associated with the treatment response to bumetanide in young children with autism spectrum disorder. ( Dai, Y; He, H; Langley, C; Li, F; Li, Q; Li, WG; Luo, Q; Sahakian, BJ; Shan, H; Yao, Y; Yu, J; Zhang, L, 2022) |
| "Magnetic resonance spectroscopy (MRS) was utilized to investigate sex differences in gamma-aminobutyric acid (GABA) between adults with autism spectrum disorder (ASD) and neurotypical (NT) controls." | 7.88 | Short communication: Sex-linked differences in gamma-aminobutyric acid (GABA) are related to social functioning in autism spectrum disorder. ( Enticott, PG; Fitzgerald, PB; Kirkovski, M; Suo, C; Yücel, M, 2018) |
| "Bumetanide has been reported to alter synaptic excitation-inhibition (E-I) balance by potentiating the action of γ-aminobutyric acid (GABA), thereby attenuating the severity of autism spectrum disorder (ASD) in animal models." | 6.94 | Symptom improvement in children with autism spectrum disorder following bumetanide administration is associated with decreased GABA/glutamate ratios. ( Dai, Y; Deng, S; Du, X; Feng, J; Huang, CC; Ji, Y; Li, F; Lin, CP; Luo, Q; Sahakian, BJ; Shen, C; Tang, Y; Wang, K; Xu, M; Yu, J; Zhang, L, 2020) |
| "Primary [Children Autism Rating Scale (CARS)], secondary [Clinical Global Impressions (CGI)], and exploratory [inhibitory (γ-aminobutyric acid, GABA) and excitatory (glutamate, Glx) neurotransmitter concentrations measured in the insular cortex (IC) and visual cortex (VC) by magnetic resonance spectroscopy (MRS)] outcome measures were evaluated at baseline and at the 3-month follow-up." | 6.94 | Symptom improvement in children with autism spectrum disorder following bumetanide administration is associated with decreased GABA/glutamate ratios. ( Dai, Y; Deng, S; Du, X; Feng, J; Huang, CC; Ji, Y; Li, F; Lin, CP; Luo, Q; Sahakian, BJ; Shen, C; Tang, Y; Wang, K; Xu, M; Yu, J; Zhang, L, 2020) |
| " Future studies should examine the effects of chronic administration on brain and behaviour, and whether acute brain changes predict longer-term response." | 6.90 | Effects of cannabidiol on brain excitation and inhibition systems; a randomised placebo-controlled single dose trial during magnetic resonance spectroscopy in adults with and without autism spectrum disorder. ( Ajram, L; Daly, E; Edden, RAE; Freyberg, J; Heasman, M; Horder, J; Ivin, G; Lythgoe, D; McAlonan, GM; Mendez, MA; Murphy, DGM; Pretzsch, CM; Voinescu, B; Wichers, R; Williams, S, 2019) |
| "Theanine is a derivative of glutamine and a natural component of green tea." | 6.72 | Possibility that the Onset of Autism Spectrum Disorder is Induced by Failure of the Glutamine-Glutamate Cycle. ( Kawada, K; Kuramoto, N; Mimori, S, 2021) |
| " Pregnant C57BL/6 J mice were intraperitoneally injected with a dosage of 500 mg/kg valproic acid (VPA) on embryonic day 10." | 5.72 | Size anomaly and alteration of GABAergic enzymes expressions in cerebellum of a valproic acid mouse model of autism. ( Kwan, KM; Ma, SY, 2022) |
| "Bumetanide, a drug being studied in autism spectrum disorder (ASD) may act to restore gamma-aminobutyric acid (GABA) function, which may be modulated by the immune system." | 5.72 | The immuno-behavioural covariation associated with the treatment response to bumetanide in young children with autism spectrum disorder. ( Dai, Y; He, H; Langley, C; Li, F; Li, Q; Li, WG; Luo, Q; Sahakian, BJ; Shan, H; Yao, Y; Yu, J; Zhang, L, 2022) |
| "With the current limited drug therapy for the core symptoms of autism spectrum disorder (ASD), we herein report a randomized, double-blind, placebo-controlled trial to investigate the efficacy, safety, and potential neural mechanism of bumetanide in children with ASD aged 3-6 years old." | 5.41 | Improved symptoms following bumetanide treatment in children aged 3-6 years with autism spectrum disorder: a randomized, double-blind, placebo-controlled trial. ( Dai, Y; Deng, S; Du, X; Feng, J; He, H; Ji, Y; Langley, C; Li, F; Li, WG; Liu, X; Luo, Q; Sahakian, BJ; Tang, Y; Wang, K; Yu, J; Zhang, J; Zhang, L; Zhou, X, 2021) |
| "Bumetanide has been reported to alter synaptic excitation-inhibition (E-I) balance by potentiating the action of γ-aminobutyric acid (GABA), thereby attenuating the severity of autism spectrum disorder (ASD) in animal models." | 5.34 | Symptom improvement in children with autism spectrum disorder following bumetanide administration is associated with decreased GABA/glutamate ratios. ( Dai, Y; Deng, S; Du, X; Feng, J; Huang, CC; Ji, Y; Li, F; Lin, CP; Luo, Q; Sahakian, BJ; Shen, C; Tang, Y; Wang, K; Xu, M; Yu, J; Zhang, L, 2020) |
| "There is increasing interest in the use of cannabis and its major non-intoxicating component cannabidiol (CBD) as a treatment for mental health and neurodevelopmental disorders, such as autism spectrum disorder (ASD)." | 5.30 | Effects of cannabidiol on brain excitation and inhibition systems; a randomised placebo-controlled single dose trial during magnetic resonance spectroscopy in adults with and without autism spectrum disorder. ( Ajram, L; Daly, E; Edden, RAE; Freyberg, J; Heasman, M; Horder, J; Ivin, G; Lythgoe, D; McAlonan, GM; Mendez, MA; Murphy, DGM; Pretzsch, CM; Voinescu, B; Wichers, R; Williams, S, 2019) |
| "A review of studies on the body fluid levels of neuroactive amino acids, including glutamate, glutamine, taurine, gamma-aminobutyric acid (GABA), glycine, tryptophan, D-serine, and others, in autism spectrum disorders (ASD) is given." | 4.95 | Body fluid levels of neuroactive amino acids in autism spectrum disorders: a review of the literature. ( Baker, GB; Li, XM; Rauw, G; Wang, WQ; Zheng, HF, 2017) |
| "Neurodevelopmental disorders (NDDs) including autism spectrum disorder (ASD), attention-deficit hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD) are thought to arise in part from the disruption in the excitatory/inhibitory balance of gamma-aminobutyric acid (GABA) and glutamate in the brain." | 4.31 | Cerebellar gamma-aminobutyric acid: Investigation of group effects in neurodevelopmental disorders. ( Anagnostou, E; Arnold, PD; Crosbie, J; Hammill, C; Lerch, JP; Near, J; Pang, EW; Schachar, R; Taylor, MJ, 2023) |
| "Altered signaling of the chief inhibitory neurotransmitter, gamma-aminobutyric acid (GABA), has been speculated in the etiology of autism spectrum disorder (ASD)." | 4.12 | GABA Receptor SNPs and Elevated Plasma GABA Levels Affect the Severity of the Indian ASD Probands. ( Chatterjee, M; Dutta, N; Mukhopadhyay, K; Saha, S; Sinha, S, 2022) |
| "The excitatory-inhibitory imbalance hypothesis postulates dysregulation of the gamma-aminobutyric acid (GABA) and glutamate (Glu) neurotransmitter systems as a common underlying deficit in individuals with autism spectrum disorders (ASD)." | 4.12 | Increased prefrontal GABA concentrations in adults with autism spectrum disorders. ( Dacko, M; Domschke, K; Düppers, AL; Ebert, D; Endres, D; Fangmeier, T; Lange, T; Maier, S; Nickel, K; Perlov, E; Riedel, A; Runge, K; Tebartz van Elst, L, 2022) |
| "Bumetanide, a drug being studied in autism spectrum disorder (ASD) may act to restore gamma-aminobutyric acid (GABA) function, which may be modulated by the immune system." | 4.12 | The immuno-behavioural covariation associated with the treatment response to bumetanide in young children with autism spectrum disorder. ( Dai, Y; He, H; Langley, C; Li, F; Li, Q; Li, WG; Luo, Q; Sahakian, BJ; Shan, H; Yao, Y; Yu, J; Zhang, L, 2022) |
| "Before we elaborate on the postulated discrepancies between our trial and previous bumetanide in autism spectrum disorder (ASD) trials, we would like to acknowledge the crucial pioneering work on the γ-aminobutyric acid (GABA) developmental sequence by Dr." | 4.02 | Dr. Sprengers et al. Reply. ( Bruining, H; Sprengers, JJ; van Andel, DM, 2021) |
| "Bumetanide has been reported to alter synaptic excitation-inhibition (E-I) balance by potentiating the action of γ-aminobutyric acid (GABA), thereby attenuating the severity of autism spectrum disorder (ASD) in animal models." | 2.94 | Symptom improvement in children with autism spectrum disorder following bumetanide administration is associated with decreased GABA/glutamate ratios. ( Dai, Y; Deng, S; Du, X; Feng, J; Huang, CC; Ji, Y; Li, F; Lin, CP; Luo, Q; Sahakian, BJ; Shen, C; Tang, Y; Wang, K; Xu, M; Yu, J; Zhang, L, 2020) |
| "Primary [Children Autism Rating Scale (CARS)], secondary [Clinical Global Impressions (CGI)], and exploratory [inhibitory (γ-aminobutyric acid, GABA) and excitatory (glutamate, Glx) neurotransmitter concentrations measured in the insular cortex (IC) and visual cortex (VC) by magnetic resonance spectroscopy (MRS)] outcome measures were evaluated at baseline and at the 3-month follow-up." | 2.94 | Symptom improvement in children with autism spectrum disorder following bumetanide administration is associated with decreased GABA/glutamate ratios. ( Dai, Y; Deng, S; Du, X; Feng, J; Huang, CC; Ji, Y; Li, F; Lin, CP; Luo, Q; Sahakian, BJ; Shen, C; Tang, Y; Wang, K; Xu, M; Yu, J; Zhang, L, 2020) |
| " Future studies should examine the effects of chronic administration on brain and behaviour, and whether acute brain changes predict longer-term response." | 2.90 | Effects of cannabidiol on brain excitation and inhibition systems; a randomised placebo-controlled single dose trial during magnetic resonance spectroscopy in adults with and without autism spectrum disorder. ( Ajram, L; Daly, E; Edden, RAE; Freyberg, J; Heasman, M; Horder, J; Ivin, G; Lythgoe, D; McAlonan, GM; Mendez, MA; Murphy, DGM; Pretzsch, CM; Voinescu, B; Wichers, R; Williams, S, 2019) |
| "Theanine is a derivative of glutamine and a natural component of green tea." | 2.72 | Possibility that the Onset of Autism Spectrum Disorder is Induced by Failure of the Glutamine-Glutamate Cycle. ( Kawada, K; Kuramoto, N; Mimori, S, 2021) |
| "The consequences of insomnia, including issues with mood, behavior, and cognition, are discussed." | 2.53 | Pediatric Insomnia. ( Brown, KM; Malow, BA, 2016) |
| "Autism spectrum disorders are an emerging health problem worldwide, but little is known about their pathogenesis." | 2.53 | Pharmacological Modulation of GABA Function in Autism Spectrum Disorders: A Systematic Review of Human Studies. ( Barale, F; Brondino, N; Damiani, S; Fusar-Poli, L; Panisi, C; Politi, P, 2016) |
| "Autism and epilepsy are two associated disorders that are highly prevalent, share common developmental origins, and demonstrate substantial heritability." | 2.53 | Cortical interneuron dysfunction in epilepsy associated with autism spectrum disorders. ( Jacob, J, 2016) |
| "Bumetanide, a drug being studied in autism spectrum disorder (ASD) may act to restore gamma-aminobutyric acid (GABA) function, which may be modulated by the immune system." | 1.72 | The immuno-behavioural covariation associated with the treatment response to bumetanide in young children with autism spectrum disorder. ( Dai, Y; He, H; Langley, C; Li, F; Li, Q; Li, WG; Luo, Q; Sahakian, BJ; Shan, H; Yao, Y; Yu, J; Zhang, L, 2022) |
| " Pregnant C57BL/6 J mice were intraperitoneally injected with a dosage of 500 mg/kg valproic acid (VPA) on embryonic day 10." | 1.72 | Size anomaly and alteration of GABAergic enzymes expressions in cerebellum of a valproic acid mouse model of autism. ( Kwan, KM; Ma, SY, 2022) |
| "Medical history interviews, seizure surveys, Vineland Adaptive Behavior Scales Second Edition and other behavioural surveys were completed by primary care givers of 28 participants in Simons Searchlight." | 1.72 | Neurodevelopmental phenotypes associated with pathogenic variants in ( Brooks, E; Chung, W; Geltzeiler, A; Green Snyder, L; Kahen, A; Kavus, H; Kentros, C; Taylor, C, 2022) |
| "Gamma-aminobutyric acid (GABA) has been hypothesized to play a role in tactile hypersensitivity." | 1.51 | Tactile hypersensitivity and GABA concentration in the sensorimotor cortex of adults with autism. ( Lamberton, F; Mattout, J; Sapey-Triomphe, LA; Schmitz, C; Sonié, S, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 38 (44.19) | 24.3611 |
| 2020's | 48 (55.81) | 2.80 |
| Authors | Studies |
|---|---|
| Ahring, PK | 1 |
| Liao, VWY | 1 |
| Gardella, E | 1 |
| Johannesen, KM | 1 |
| Krey, I | 1 |
| Selmer, KK | 1 |
| Stadheim, BF | 1 |
| Davis, H | 1 |
| Peinhardt, C | 1 |
| Koko, M | 1 |
| Coorg, RK | 1 |
| Syrbe, S | 1 |
| Bertsche, A | 1 |
| Santiago-Sim, T | 1 |
| Diemer, T | 1 |
| Fenger, CD | 1 |
| Platzer, K | 1 |
| Eichler, EE | 1 |
| Lerche, H | 1 |
| Lemke, JR | 1 |
| Chebib, M | 1 |
| Møller, RS | 1 |
| Huang, Q | 2 |
| Pereira, AC | 3 |
| Velthuis, H | 3 |
| Wong, NML | 2 |
| Ellis, CL | 2 |
| Ponteduro, FM | 2 |
| Dimitrov, M | 2 |
| Kowalewski, L | 2 |
| Lythgoe, DJ | 3 |
| Rotaru, D | 1 |
| Edden, RAE | 7 |
| Leonard, A | 1 |
| Ivin, G | 5 |
| Ahmad, J | 2 |
| Pretzsch, CM | 4 |
| Daly, E | 4 |
| Murphy, DGM | 6 |
| McAlonan, GM | 5 |
| James, D | 2 |
| Lam, VT | 1 |
| Jo, B | 2 |
| Fung, LK | 2 |
| Santrač, A | 1 |
| Bijelić, D | 1 |
| Stevanović, V | 1 |
| Banićević, M | 1 |
| Aranđelović, J | 1 |
| Batinić, B | 1 |
| Sharmin, D | 1 |
| Cook, JM | 1 |
| Savić, MM | 1 |
| Ma, SY | 1 |
| Kwan, KM | 1 |
| Bove, M | 1 |
| Schiavone, S | 1 |
| Tucci, P | 1 |
| Sikora, V | 1 |
| Dimonte, S | 1 |
| Colia, AL | 1 |
| Morgese, MG | 1 |
| Trabace, L | 1 |
| Lee, IO | 1 |
| Skuse, DH | 1 |
| Constable, PA | 1 |
| Marmolejo-Ramos, F | 1 |
| Olsen, LR | 1 |
| Thompson, DA | 1 |
| Saha, S | 2 |
| Chatterjee, M | 2 |
| Dutta, N | 1 |
| Sinha, S | 4 |
| Mukhopadhyay, K | 2 |
| Maier, S | 1 |
| Düppers, AL | 1 |
| Runge, K | 1 |
| Dacko, M | 1 |
| Lange, T | 1 |
| Fangmeier, T | 1 |
| Riedel, A | 1 |
| Ebert, D | 1 |
| Endres, D | 1 |
| Domschke, K | 1 |
| Perlov, E | 1 |
| Nickel, K | 1 |
| Tebartz van Elst, L | 1 |
| Li, Q | 1 |
| Zhang, L | 3 |
| Shan, H | 1 |
| Yu, J | 3 |
| Dai, Y | 3 |
| He, H | 2 |
| Li, WG | 2 |
| Langley, C | 2 |
| Sahakian, BJ | 3 |
| Yao, Y | 1 |
| Luo, Q | 3 |
| Li, F | 3 |
| Chu, MC | 1 |
| Wu, HF | 1 |
| Lee, CW | 1 |
| Chung, YJ | 1 |
| Chi, H | 1 |
| Chen, PS | 1 |
| Lin, HC | 1 |
| Singla, R | 2 |
| Mishra, A | 2 |
| Joshi, R | 1 |
| Sarma, P | 1 |
| Kumar, R | 1 |
| Kaur, G | 1 |
| Sharma, AR | 2 |
| Jain, A | 2 |
| Prakash, A | 1 |
| Bhatia, A | 1 |
| Medhi, B | 2 |
| Carey, C | 1 |
| Singh, N | 1 |
| Dunn, JT | 1 |
| Sementa, T | 1 |
| Mendez, MA | 5 |
| Horder, J | 5 |
| Hader, S | 1 |
| Rotaru, DG | 1 |
| Gee, A | 1 |
| Cash, D | 1 |
| Veronese, M | 1 |
| Murphy, D | 1 |
| McAlonan, G | 1 |
| Pang, EW | 1 |
| Hammill, C | 1 |
| Taylor, MJ | 1 |
| Near, J | 1 |
| Schachar, R | 1 |
| Crosbie, J | 1 |
| Arnold, PD | 1 |
| Anagnostou, E | 1 |
| Lerch, JP | 1 |
| Zhou, X | 1 |
| Ji, Y | 2 |
| Wang, K | 2 |
| Du, X | 2 |
| Liu, X | 1 |
| Tang, Y | 2 |
| Deng, S | 2 |
| Zhang, J | 1 |
| Feng, J | 2 |
| Hollestein, V | 1 |
| Poelmans, G | 2 |
| Forde, NJ | 1 |
| Beckmann, CF | 1 |
| Ecker, C | 1 |
| Mann, C | 1 |
| Schäfer, T | 1 |
| Moessnang, C | 1 |
| Baumeister, S | 1 |
| Banaschewski, T | 1 |
| Bourgeron, T | 1 |
| Loth, E | 1 |
| Dell'Acqua, F | 1 |
| Puts, NA | 2 |
| Tillmann, J | 1 |
| Charman, T | 1 |
| Jones, EJH | 1 |
| Mason, L | 1 |
| Ambrosino, S | 1 |
| Holt, R | 1 |
| Bölte, S | 1 |
| Buitelaar, JK | 2 |
| Naaijen, J | 2 |
| Zohny, SM | 1 |
| Habib, MZ | 1 |
| Mohamad, MI | 1 |
| Elayat, WM | 1 |
| Elhossiny, RM | 1 |
| El-Salam, MFA | 1 |
| Hassan, GAM | 1 |
| Aboul-Fotouh, S | 1 |
| Adak, P | 2 |
| Banerjee, N | 2 |
| Bandyopadhyay, AK | 1 |
| Du, Y | 1 |
| Chen, L | 1 |
| Yan, MC | 1 |
| Wang, YL | 1 |
| Zhong, XL | 1 |
| Xv, CX | 1 |
| Li, YB | 1 |
| Cheng, Y | 1 |
| Tokatly Latzer, I | 1 |
| Hanson, E | 1 |
| Bertoldi, M | 1 |
| García-Cazorla, À | 1 |
| Tsuboyama, M | 1 |
| MacMullin, P | 1 |
| Rotenberg, A | 1 |
| Roullet, JB | 1 |
| Pearl, PL | 1 |
| Wang, X | 2 |
| Zhao, Z | 1 |
| Guo, J | 1 |
| Mei, D | 1 |
| Duan, Y | 1 |
| Zhang, Y | 1 |
| Gou, L | 1 |
| Cooke, SF | 1 |
| Puts, NAJ | 3 |
| Batalle, D | 1 |
| Hours, CM | 1 |
| Gil, S | 1 |
| Gressens, P | 1 |
| Johnson, AJ | 1 |
| Shankland, E | 1 |
| Richards, T | 1 |
| Corrigan, N | 1 |
| Shusterman, D | 1 |
| Edden, R | 1 |
| Estes, A | 1 |
| St John, T | 1 |
| Dager, S | 1 |
| Kleinhans, NM | 1 |
| El-Ansary, A | 4 |
| Zayed, N | 1 |
| Al-Ayadhi, L | 4 |
| Qasem, H | 2 |
| Anwar, M | 1 |
| Meguid, NA | 1 |
| Bhat, RS | 1 |
| Doşa, MD | 1 |
| Chirumbolo, S | 2 |
| Bjørklund, G | 2 |
| Ford, TC | 2 |
| Woods, W | 1 |
| Enticott, PG | 2 |
| Crewther, DP | 2 |
| Voinescu, B | 2 |
| Lythgoe, D | 2 |
| Wichers, R | 2 |
| Ajram, L | 2 |
| Heasman, M | 3 |
| Williams, S | 2 |
| Saitow, F | 1 |
| Takumi, T | 2 |
| Suzuki, H | 1 |
| Edmondson, DA | 1 |
| Xia, P | 1 |
| McNally Keehn, R | 1 |
| Dydak, U | 1 |
| Keehn, B | 1 |
| Di, J | 1 |
| Li, J | 2 |
| O'Hara, B | 1 |
| Alberts, I | 1 |
| Xiong, L | 1 |
| Li, X | 1 |
| Umesawa, Y | 1 |
| Matsushima, K | 1 |
| Atsumi, T | 1 |
| Kato, T | 1 |
| Fukatsu, R | 1 |
| Wada, M | 2 |
| Ide, M | 1 |
| Huang, CC | 1 |
| Xu, M | 1 |
| Shen, C | 1 |
| Lin, CP | 1 |
| Rein, B | 1 |
| Tan, T | 1 |
| Yang, F | 1 |
| Wang, W | 1 |
| Williams, J | 1 |
| Zhang, F | 1 |
| Mills, A | 1 |
| Yan, Z | 1 |
| Kawada, K | 1 |
| Kuramoto, N | 1 |
| Mimori, S | 1 |
| Kolodny, T | 1 |
| Schallmo, MP | 1 |
| Gerdts, J | 1 |
| Bernier, RA | 1 |
| Murray, SO | 1 |
| Hong, T | 1 |
| Falcone, C | 1 |
| Dufour, B | 1 |
| Amina, S | 1 |
| Castro, RP | 1 |
| Regalado, J | 1 |
| Pearson, W | 1 |
| Noctor, SC | 1 |
| Martínez-Cerdeño, V | 1 |
| Flores, RE | 1 |
| Gu, M | 1 |
| Sun, KL | 1 |
| Schuck, RK | 1 |
| Park, JH | 1 |
| Lee, BC | 1 |
| Jung, JH | 1 |
| Kim, SE | 1 |
| Saggar, M | 1 |
| Sacchet, MD | 1 |
| Warnock, G | 1 |
| Khalighi, MM | 1 |
| Spielman, D | 1 |
| Chin, FT | 1 |
| Hardan, AY | 1 |
| Heinze, K | 1 |
| Barron, HC | 1 |
| Howes, EK | 1 |
| Ramaswami, M | 1 |
| Broome, MR | 1 |
| Yang, JQ | 1 |
| Yang, CH | 1 |
| Yin, BQ | 1 |
| Sprengers, JJ | 1 |
| van Andel, DM | 1 |
| Bruining, H | 1 |
| DeMayo, MM | 1 |
| Harris, AD | 3 |
| Song, YJC | 1 |
| Pokorski, I | 1 |
| Thapa, R | 1 |
| Patel, S | 1 |
| Ambarchi, Z | 1 |
| Thomas, EE | 1 |
| Hickie, IB | 1 |
| Guastella, AJ | 1 |
| Kahen, A | 1 |
| Kavus, H | 1 |
| Geltzeiler, A | 1 |
| Kentros, C | 1 |
| Taylor, C | 1 |
| Brooks, E | 1 |
| Green Snyder, L | 1 |
| Chung, W | 1 |
| Zheng, F | 1 |
| Liu, G | 1 |
| Dang, T | 1 |
| Chen, Q | 1 |
| An, Y | 1 |
| Wu, M | 1 |
| Kong, X | 1 |
| Qiu, Z | 1 |
| Wu, BL | 1 |
| He, JL | 1 |
| Oeltzschner, G | 1 |
| Mikkelsen, M | 1 |
| Deronda, A | 1 |
| Crocetti, D | 2 |
| Wodka, EL | 2 |
| Mostofsky, SH | 2 |
| Batra, G | 1 |
| Saini, L | 1 |
| Sharma, S | 1 |
| Singh, A | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of Creatine Supplementation in Autism Spectrum Disorder: a Randomized Placebo-controlled Trial[NCT04498078] | 20 participants (Actual) | Interventional | 2022-01-15 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
15 reviews available for gamma-aminobutyric acid and Autism Spectrum Disorder
| Article | Year |
|---|---|
Neurometabolite levels in the brains of patients with autism spectrum disorders: A meta-analysis of proton magnetic resonance spectroscopy studies (N = 1501).
Topics: Aspartic Acid; Autism Spectrum Disorder; Brain; Choline; gamma-Aminobutyric Acid; Glutamic Acid; Hum | 2023 |
The role of GABAergic neural circuits in the pathogenesis of autism spectrum disorder.
Topics: Adolescent; Autism Spectrum Disorder; Brain; Child; Child, Preschool; gamma-Aminobutyric Acid; Human | 2020 |
Possibility that the Onset of Autism Spectrum Disorder is Induced by Failure of the Glutamine-Glutamate Cycle.
Topics: Autism Spectrum Disorder; Brain; Endoplasmic Reticulum Stress; gamma-Aminobutyric Acid; Glutamates; | 2021 |
Impaired inhibitory processing: a new therapeutic target for autism and psychosis?
Topics: Autism Spectrum Disorder; Autistic Disorder; Brain; gamma-Aminobutyric Acid; Humans; Inhibition, Psy | 2021 |
Valproic Acid and Propionic Acid Modulated Mechanical Pathways Associated with Autism Spectrum Disorder at Prenatal and Neonatal Exposure.
Topics: Animals; Autism Spectrum Disorder; Behavior, Animal; Disease Models, Animal; Female; Food Preservati | 2022 |
Neurobiological bases of autism-epilepsy comorbidity: a focus on excitation/inhibition imbalance.
Topics: Animals; Autism Spectrum Disorder; Comorbidity; Cortical Excitability; Epilepsy; gamma-Aminobutyric | 2018 |
Synaptopathology in autism spectrum disorders: Complex effects of synaptic genes on neural circuits.
Topics: Animals; Autism Spectrum Disorder; Brain; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Synapses; | 2018 |
Cortical interneuron function in autism spectrum condition.
Topics: Animals; Autism Spectrum Disorder; Cerebral Cortex; Electroencephalography; gamma-Aminobutyric Acid; | 2019 |
[A review on the role of γ-aminobutyric acid signaling pathway in autism spectrum disorder].
Topics: Animals; Autism Spectrum Disorder; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; H | 2018 |
Motor cortex excitability and inhibitory imbalance in autism spectrum disorder assessed with transcranial magnetic stimulation: a systematic review.
Topics: Autism Spectrum Disorder; Evoked Potentials, Motor; gamma-Aminobutyric Acid; Humans; Motor Cortex; N | 2019 |
Pediatric Insomnia.
Topics: Actigraphy; Adolescent; Amines; Anti-Anxiety Agents; Autism Spectrum Disorder; Central Nervous Syste | 2016 |
Pharmacological Modulation of GABA Function in Autism Spectrum Disorders: A Systematic Review of Human Studies.
Topics: Autism Spectrum Disorder; GABA Modulators; gamma-Aminobutyric Acid; Humans | 2016 |
Cortical interneuron dysfunction in epilepsy associated with autism spectrum disorders.
Topics: Aicardi Syndrome; Autism Spectrum Disorder; Cerebral Cortex; Child; Child, Preschool; Epilepsies, My | 2016 |
Measuring neural excitation and inhibition in autism: Different approaches, different findings and different interpretations.
Topics: Adult; Animals; Autism Spectrum Disorder; Brain; Electroencephalography; Gamma Rhythm; gamma-Aminobu | 2016 |
Body fluid levels of neuroactive amino acids in autism spectrum disorders: a review of the literature.
Topics: Amino Acids; Autism Spectrum Disorder; Body Fluids; gamma-Aminobutyric Acid; Glutamic Acid; Glutamin | 2017 |
7 trials available for gamma-aminobutyric acid and Autism Spectrum Disorder
| Article | Year |
|---|---|
GABA
Topics: Adult; Autism Spectrum Disorder; Evoked Potentials, Visual; gamma-Aminobutyric Acid; Humans; Magneti | 2022 |
Improved symptoms following bumetanide treatment in children aged 3-6 years with autism spectrum disorder: a randomized, double-blind, placebo-controlled trial.
Topics: Autism Spectrum Disorder; Autistic Disorder; Bumetanide; Child; Child, Preschool; gamma-Aminobutyric | 2021 |
Exploratory evidence for differences in GABAergic regulation of auditory processing in autism spectrum disorder.
Topics: Adult; Auditory Perception; Autism Spectrum Disorder; Autistic Disorder; GABA-B Receptor Agonists; g | 2023 |
Effects of cannabidivarin (CBDV) on brain excitation and inhibition systems in adults with and without Autism Spectrum Disorder (ASD): a single dose trial during magnetic resonance spectroscopy.
Topics: Adult; Autism Spectrum Disorder; Basal Ganglia; Cannabinoids; Cross-Over Studies; Double-Blind Metho | 2019 |
Symptom improvement in children with autism spectrum disorder following bumetanide administration is associated with decreased GABA/glutamate ratios.
Topics: Autism Spectrum Disorder; Autistic Disorder; Bumetanide; Child; Child, Preschool; gamma-Aminobutyric | 2020 |
Effects of cannabidiol on brain excitation and inhibition systems; a randomised placebo-controlled single dose trial during magnetic resonance spectroscopy in adults with and without autism spectrum disorder.
Topics: Adult; Autism Spectrum Disorder; Basal Ganglia; Cannabidiol; Double-Blind Method; gamma-Aminobutyric | 2019 |
A double-blind, placebo-controlled, randomised-designed GABA tea study in children diagnosed with autism spectrum conditions: a feasibility study clinical trial registration: ISRCTN 72571312.
Topics: Adolescent; Autism Spectrum Disorder; Child; Double-Blind Method; Feasibility Studies; Female; gamma | 2021 |
64 other studies available for gamma-aminobutyric acid and Autism Spectrum Disorder
| Article | Year |
|---|---|
Gain-of-function variants in GABRD reveal a novel pathway for neurodevelopmental disorders and epilepsy.
Topics: Autism Spectrum Disorder; Epilepsy; Epilepsy, Generalized; GABA Plasma Membrane Transport Proteins; | 2022 |
Region-specific associations between gamma-aminobutyric acid A receptor binding and cortical thickness in high-functioning autistic adults.
Topics: Adult; Autism Spectrum Disorder; Autistic Disorder; Brain; Brain Mapping; Female; gamma-Aminobutyric | 2022 |
Postweaning positive modulation of α5GABAA receptors improves autism-like features in prenatal valproate rat model in a sex-specific manner.
Topics: Animals; Autism Spectrum Disorder; Autistic Disorder; Behavior, Animal; Calcium; Disease Models, Ani | 2022 |
Size anomaly and alteration of GABAergic enzymes expressions in cerebellum of a valproic acid mouse model of autism.
Topics: Animals; Autism Spectrum Disorder; Autistic Disorder; Cerebellum; Disease Models, Animal; Female; ga | 2022 |
Ketamine administration in early postnatal life as a tool for mimicking Autism Spectrum Disorders core symptoms.
Topics: Animals; Autism Spectrum Disorder; Brain-Derived Neurotrophic Factor; Disease Models, Animal; gamma- | 2022 |
The electroretinogram b-wave amplitude: a differential physiological measure for Attention Deficit Hyperactivity Disorder and Autism Spectrum Disorder.
Topics: Adolescent; Adult; Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Child; C | 2022 |
GABA Receptor SNPs and Elevated Plasma GABA Levels Affect the Severity of the Indian ASD Probands.
Topics: Asian People; Autism Spectrum Disorder; gamma-Aminobutyric Acid; Humans; Polymorphism, Single Nucleo | 2022 |
Increased prefrontal GABA concentrations in adults with autism spectrum disorders.
Topics: Adult; Autism Spectrum Disorder; Creatine; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans | 2022 |
The immuno-behavioural covariation associated with the treatment response to bumetanide in young children with autism spectrum disorder.
Topics: Autism Spectrum Disorder; Autistic Disorder; Bumetanide; Child; Child, Preschool; Cytokines; gamma-A | 2022 |
Generational synaptic functions of GABA
Topics: Animals; Autism Spectrum Disorder; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Humans; | 2022 |
Homotaurine ameliorates the core ASD symptomatology in VPA rats through GABAergic signaling: Role of GAD67.
Topics: Animals; Autism Spectrum Disorder; Behavior, Animal; Disease Models, Animal; Female; gamma-Aminobuty | 2022 |
From bench to bedside: The mGluR5 system in people with and without Autism Spectrum Disorder and animal model systems.
Topics: Adult; Animals; Autism Spectrum Disorder; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic | 2022 |
Cerebellar gamma-aminobutyric acid: Investigation of group effects in neurodevelopmental disorders.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Case-Control St | 2023 |
Excitatory/inhibitory imbalance in autism: the role of glutamate and GABA gene-sets in symptoms and cortical brain structure.
Topics: Adolescent; Adult; Autism Spectrum Disorder; Autistic Disorder; Brain; Female; gamma-Aminobutyric Ac | 2023 |
Memantine/Aripiprazole Combination Alleviates Cognitive Dysfunction in Valproic Acid Rat Model of Autism: Hippocampal CREB/BDNF Signaling and Glutamate Homeostasis.
Topics: Animals; Aripiprazole; Autism Spectrum Disorder; Autistic Disorder; Brain-Derived Neurotrophic Facto | 2023 |
Gamma-Aminobutyric Acid Type A Receptor Variants are Associated with Autism Spectrum Disorders.
Topics: Autism Spectrum Disorder; Autistic Disorder; Child; gamma-Aminobutyric Acid; Humans; Polymorphism, S | 2023 |
Autism spectrum disorder and GABA levels in children with succinic semialdehyde dehydrogenase deficiency.
Topics: Autism Spectrum Disorder; Child; Developmental Disabilities; Female; gamma-Aminobutyric Acid; Humans | 2023 |
GABA
Topics: Animals; Autism Spectrum Disorder; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Humans; | 2023 |
Molecular and Cellular Insights: A Focus on Glycans and the HNK1 Epitope in Autism Spectrum Disorder.
Topics: Autism Spectrum Disorder; Epitopes; Female; gamma-Aminobutyric Acid; Glutamates; Humans; Infant, New | 2023 |
Relationships between GABA, glutamate, and GABA/glutamate and social and olfactory processing in children with autism spectrum disorder.
Topics: Autism Spectrum Disorder; Child; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Magnetic Resonance | 2023 |
GABA synaptopathy promotes the elevation of caspases 3 and 9 as pro-apoptotic markers in Egyptian patients with autism spectrum disorder.
Topics: Apoptosis; Autism Spectrum Disorder; Biomarkers; Caspase 3; Caspase 9; Child, Preschool; Egypt; Fema | 2021 |
Cortical excitation-inhibition ratio mediates the effect of pre-attentive auditory processing deficits on interpersonal difficulties.
Topics: Adolescent; Adult; Auditory Perception; Autism Spectrum Disorder; Cerebral Cortex; Female; gamma-Ami | 2020 |
Change in serotonergic modulation contributes to the synaptic imbalance of neuronal circuit at the prefrontal cortex in the 15q11-13 duplication mouse model of autism.
Topics: Animals; Autism Spectrum Disorder; Cortical Excitability; Disease Models, Animal; DNA Copy Number Va | 2020 |
A Magnetic Resonance Spectroscopy Study of Superior Visual Search Abilities in Children with Autism Spectrum Disorder.
Topics: Adolescent; Aspartic Acid; Attention; Autism Spectrum Disorder; Brain; Child; Creatine; Female; gamm | 2020 |
Altered GABA Concentration in Brain Motor Area Is Associated with the Severity of Motor Disabilities in Individuals with Autism Spectrum Disorder.
Topics: Adolescent; Adult; Autism Spectrum Disorder; Brain; Female; gamma-Aminobutyric Acid; Humans; Magneti | 2020 |
Reversal of synaptic and behavioral deficits in a 16p11.2 duplication mouse model via restoration of the GABA synapse regulator Npas4.
Topics: Animals; Autism Spectrum Disorder; Basic Helix-Loop-Helix Transcription Factors; Chromosome Deletion | 2021 |
Concentrations of Cortical GABA and Glutamate in Young Adults With Autism Spectrum Disorder.
Topics: Autism Spectrum Disorder; Bayes Theorem; Female; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; | 2020 |
GABA
Topics: Autism Spectrum Disorder; Autistic Disorder; Axon Initial Segment; gamma-Aminobutyric Acid; Humans; | 2020 |
Thalamic and prefrontal GABA concentrations but not GABA
Topics: Adult; Autism Spectrum Disorder; Autistic Disorder; Female; gamma-Aminobutyric Acid; Humans; Male; P | 2021 |
Combined the GABA-A and GABA-B receptor agonists attenuates autistic behaviors in a prenatal valproic acid-induced mouse model of autism.
Topics: Animals; Anticonvulsants; Autism Spectrum Disorder; Behavior, Animal; Disease Models, Animal; Drug T | 2021 |
An Association Study of Gamma-Aminobutyric Acid Type A Receptor Variants and Susceptibility to Autism Spectrum Disorders.
Topics: Autism Spectrum Disorder; gamma-Aminobutyric Acid; Humans; Pilot Projects; Polymorphism, Single Nucl | 2021 |
Dr. Sprengers et al. Reply.
Topics: Animals; Autism Spectrum Disorder; Autistic Disorder; Bumetanide; gamma-Aminobutyric Acid; Humans; N | 2021 |
Age-related parietal GABA alterations in children with autism spectrum disorder.
Topics: Adult; Autism Spectrum Disorder; Child; Cross-Sectional Studies; gamma-Aminobutyric Acid; Humans; Ma | 2021 |
A pioneering study indicate role of GABRQ rs3810651 in ASD severity of Indo-Caucasoid female probands.
Topics: Autism Spectrum Disorder; Case-Control Studies; Child; Child, Preschool; Chromosomes, Human, X; Fema | 2021 |
Neurodevelopmental phenotypes associated with pathogenic variants in
Topics: Autism Spectrum Disorder; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Humans; | 2022 |
GABA Signaling Pathway-associated Gene PLCL1 Rare Variants May be Associated with Autism Spectrum Disorders.
Topics: Autism Spectrum Disorder; gamma-Aminobutyric Acid; Humans; Signal Transduction | 2021 |
Region-specific elevations of glutamate + glutamine correlate with the sensory symptoms of autism spectrum disorders.
Topics: Autism Spectrum Disorder; Child; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Humans; Magnetic | 2021 |
A Proton Magnetic Resonance Spectroscopic Study in Autism Spectrum Disorder Using a 3-Tesla Clinical Magnetic Resonance Imaging (MRI) System: The Anterior Cingulate Cortex and the Left Cerebellum.
Topics: Adolescent; Aspartic Acid; Autism Spectrum Disorder; Cerebellum; Child; Child, Preschool; Choline; C | 2017 |
Shifting brain inhibitory balance and connectivity of the prefrontal cortex of adults with autism spectrum disorder.
Topics: Adult; Autism Spectrum Disorder; Brain; Brain Mapping; Excitatory Amino Acid Antagonists; Functional | 2017 |
Reduced protein expressions of cytomembrane GABA
Topics: Animals; Autism Spectrum Disorder; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; | 2017 |
Protocadherin 10 alters γ oscillations, amino acid levels, and their coupling; baclofen partially restores these oscillatory deficits.
Topics: Acoustic Stimulation; Animals; Auditory Perception; Autism Spectrum Disorder; Baclofen; Cadherins; C | 2017 |
The neurobiological bases of autism spectrum disorders: the R451C-neuroligin 3 mutation hampers the expression of long-term synaptic depression in the dorsal striatum.
Topics: Animals; Autism Spectrum Disorder; Cell Adhesion Molecules, Neuronal; Disease Models, Animal; Electr | 2018 |
Testing the excitation/inhibition imbalance hypothesis in a mouse model of the autism spectrum disorder: in vivo neurospectroscopy and molecular evidence for regional phenotypes.
Topics: Animals; Autism Spectrum Disorder; Disease Models, Animal; DNA-Binding Proteins; Female; gamma-Amino | 2017 |
Medial Frontal Lobe Neurochemistry in Autism Spectrum Disorder is Marked by Reduced N-Acetylaspartate and Unchanged Gamma-Aminobutyric Acid and Glutamate + Glutamine Levels.
Topics: Adolescent; Aspartic Acid; Autism Spectrum Disorder; Biomarkers; Child; Female; gamma-Aminobutyric A | 2018 |
Arid1b haploinsufficiency disrupts cortical interneuron development and mouse behavior.
Topics: Animals; Autism Spectrum Disorder; Avoidance Learning; Behavior, Animal; Cell Count; Cerebral Cortex | 2017 |
Gamma oscillatory activity in vitro: a model system to assess pathophysiological mechanisms of comorbidity between autism and epilepsy.
Topics: Animals; Autism Spectrum Disorder; Comorbidity; Electric Stimulation; Electroencephalography; Epilep | 2018 |
Understanding the roles of glutamine synthetase, glutaminase, and glutamate decarboxylase autoantibodies in imbalanced excitatory/inhibitory neurotransmission as etiological mechanisms of autism.
Topics: Autism Spectrum Disorder; Autoantibodies; Child; gamma-Aminobutyric Acid; Glutamate Decarboxylase; G | 2018 |
Relationship between absolute and relative ratios of glutamate, glutamine and GABA and severity of autism spectrum disorder.
Topics: Adolescent; Autism Spectrum Disorder; Biomarkers; Child; Cognition; gamma-Aminobutyric Acid; Glutami | 2018 |
Short communication: Sex-linked differences in gamma-aminobutyric acid (GABA) are related to social functioning in autism spectrum disorder.
Topics: Adult; Autism Spectrum Disorder; Female; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Spectro | 2018 |
Glutamate and GABA in autism spectrum disorder-a translational magnetic resonance spectroscopy study in man and rodent models.
Topics: Adult; Animals; Autism Spectrum Disorder; Brain; Corpus Striatum; Disease Models, Animal; Female; ga | 2018 |
GABAρ3 expression in lobule X of the cerebellum is reduced in the valproate model of autism.
Topics: Animals; Autism Spectrum Disorder; Behavior, Animal; Cerebellum; Disease Models, Animal; Female; gam | 2018 |
Further studies of GABA and Glutamate imbalances in autism are important challenges for future research.
Topics: Autism Spectrum Disorder; Autistic Disorder; Child; Child, Preschool; gamma-Aminobutyric Acid; Gluta | 2019 |
Tactile hypersensitivity and GABA concentration in the sensorimotor cortex of adults with autism.
Topics: Adult; Autism Spectrum Disorder; Female; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Spectro | 2019 |
Autophagy links MTOR and GABA signaling in the brain.
Topics: Animals; Autism Spectrum Disorder; Autophagy; Brain; gamma-Aminobutyric Acid; Humans; Mice; Mice, Kn | 2019 |
Psychosocial deficits across autism and schizotypal spectra are interactively modulated by excitatory and inhibitory neurotransmission.
Topics: Adolescent; Adult; Attention; Autism Spectrum Disorder; Cognition; Female; gamma-Aminobutyric Acid; | 2020 |
Enhanced Glutamatergic Currents at Birth in Shank3 KO Mice.
Topics: Animals; Animals, Newborn; Autism Spectrum Disorder; CA3 Region, Hippocampal; Disease Models, Animal | 2019 |
GABAergic/glutamatergic imbalance relative to excessive neuroinflammation in autism spectrum disorders.
Topics: Adolescent; Animals; Autism Spectrum Disorder; Biomarkers; Child; Child, Preschool; Female; gamma-Am | 2014 |
Relationship among Glutamine, γ-Aminobutyric Acid, and Social Cognition in Autism Spectrum Disorders.
Topics: Adolescent; Autism Spectrum Disorder; Cognition; Creatinine; gamma-Aminobutyric Acid; Glutamine; Gyr | 2015 |
Compromising the phosphodependent regulation of the GABAAR β3 subunit reproduces the core phenotypes of autism spectrum disorders.
Topics: Alanine; Animals; Autism Spectrum Disorder; Behavior, Animal; Biotinylation; Cell Membrane; Dendriti | 2015 |
Increased anxiety-like behaviour and altered GABAergic system in the amygdala and cerebellum of VPA rats - An animal model of autism.
Topics: Amygdala; Animals; Anxiety; Autism Spectrum Disorder; Cerebellum; Disease Models, Animal; Female; GA | 2016 |
Reduced GABA and altered somatosensory function in children with autism spectrum disorder.
Topics: Autism Spectrum Disorder; Child; Evoked Potentials, Somatosensory; Female; gamma-Aminobutyric Acid; | 2017 |
Altered neurotransmitter metabolism in adolescents with high-functioning autism.
Topics: Adolescent; Autism Spectrum Disorder; Creatine; Female; gamma-Aminobutyric Acid; Glutamic Acid; Huma | 2016 |
Exploring the relationship between cortical GABA concentrations, auditory gamma-band responses and development in ASD: Evidence for an altered maturational trajectory in ASD.
Topics: Adolescent; Adult; Age Factors; Auditory Cortex; Autism Spectrum Disorder; Cerebral Cortex; Child; E | 2017 |
Glutamatergic and GABAergic gene sets in attention-deficit/hyperactivity disorder: association to overlapping traits in ADHD and autism.
Topics: Adolescent; Amino Acid Transport System y+L; Attention Deficit Disorder with Hyperactivity; Autism S | 2017 |