gamma-aminobutyric acid has been researched along with Astrocytosis in 34 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The lithium-pilocarpine model of epilepsy reproduces in rodents several features of human temporal lobe epilepsy, by inducing an acute status epilepticus (SE) followed by a latency period." | 7.79 | Gabapentin administration reduces reactive gliosis and neurodegeneration after pilocarpine-induced status epilepticus. ( Angelo, MF; Lukin, J; Ramos, AJ; Rossi, AR; Villarreal, A, 2013) |
| "Gabapentin treatment was able to reduce reactive gliosis, decrease neuronal loss and normalize PSA-NCAM staining in hippocampal CA-1." | 5.39 | Gabapentin administration reduces reactive gliosis and neurodegeneration after pilocarpine-induced status epilepticus. ( Angelo, MF; Lukin, J; Ramos, AJ; Rossi, AR; Villarreal, A, 2013) |
| "Once SE was achieved, seizures were stopped with 20 mg/kg diazepam." | 5.39 | Gabapentin administration reduces reactive gliosis and neurodegeneration after pilocarpine-induced status epilepticus. ( Angelo, MF; Lukin, J; Ramos, AJ; Rossi, AR; Villarreal, A, 2013) |
| "The lithium-pilocarpine model of epilepsy reproduces in rodents several features of human temporal lobe epilepsy, by inducing an acute status epilepticus (SE) followed by a latency period." | 3.79 | Gabapentin administration reduces reactive gliosis and neurodegeneration after pilocarpine-induced status epilepticus. ( Angelo, MF; Lukin, J; Ramos, AJ; Rossi, AR; Villarreal, A, 2013) |
| "Although epilepsy has traditionally been thought of as a disease caused by changes in neuronal properties exclusively, these new findings challenge us to consider the contribution of glial cells as drivers of epileptogenesis in acquired epilepsies." | 2.53 | Glia as drivers of abnormal neuronal activity. ( Robel, S; Sontheimer, H, 2016) |
| "Reactive astrogliosis is a hallmark of Alzheimer's disease (AD)." | 1.91 | Visualizing reactive astrocyte-neuron interaction in Alzheimer's disease using 11C-acetate and 18F-FDG. ( Bhalla, M; Chun, JH; Chung, JI; Han, YE; Heo, J; Hyeon, SJ; Jo, HH; Ju, YH; Kim, D; Kim, H; Kim, KJ; Kim, SY; Ko, HY; Kong, M; Kwon, J; Lee, CJ; Lee, GH; Lee, H; Lee, S; Lee, SE; Nam, MH; Oh, KT; Oh, SJ; Park, KD; Park, MA; Park, YM; Ryu, H; Stein, TD; Won, W; Yun, M, 2023) |
| "Interestingly, astrogliosis observed in the BFB at the pre-plaque stage was absent at the early-plaque stage." | 1.72 | Altered basal forebrain function during whole-brain network activity at pre- and early-plaque stages of Alzheimer's disease in TgF344-AD rats. ( Adhikari, MH; De Vos, WH; Heymans, L; Keliris, GA; Missault, S; Pintelon, I; Ponsaerts, P; Van Audekerke, J; van den Berg, M; Van der Linden, A; Vasilkovska, T; Verhoye, M; Verschuuren, M, 2022) |
| "The gliosis was associated with the reduction of glial aminoacid transporters (GLT1 and GlyT1) and increase of neuronal glutamate transporter EAAC1." | 1.43 | Astrocytes and Microglia-Mediated Immune Response in Maladaptive Plasticity is Differently Modulated by NGF in the Ventral Horn of the Spinal Cord Following Peripheral Nerve Injury. ( Alberghina, L; Bianco, MR; Cirillo, G; Colangelo, AM; De Luca, C; Papa, M; Savarese, L, 2016) |
| "Although mouse models of experimental autoimmune encephalomyelitis (EAE) have provided insight on the pathobiology of MS-induced neuropathic pain, concurrent severe motor impairments confound quantitative assessment of pain behaviors over the disease course." | 1.40 | Establishment and characterization of an optimized mouse model of multiple sclerosis-induced neuropathic pain using behavioral, pharmacologic, histologic and immunohistochemical methods. ( Khan, N; Smith, MT; Woodruff, TM, 2014) |
| "Mechanical allodynia was fully developed by 28-30days post-immunization (p." | 1.40 | Establishment and characterization of an optimized mouse model of multiple sclerosis-induced neuropathic pain using behavioral, pharmacologic, histologic and immunohistochemical methods. ( Khan, N; Smith, MT; Woodruff, TM, 2014) |
| "Gabapentin treatment was able to reduce reactive gliosis, decrease neuronal loss and normalize PSA-NCAM staining in hippocampal CA-1." | 1.39 | Gabapentin administration reduces reactive gliosis and neurodegeneration after pilocarpine-induced status epilepticus. ( Angelo, MF; Lukin, J; Ramos, AJ; Rossi, AR; Villarreal, A, 2013) |
| "Once SE was achieved, seizures were stopped with 20 mg/kg diazepam." | 1.39 | Gabapentin administration reduces reactive gliosis and neurodegeneration after pilocarpine-induced status epilepticus. ( Angelo, MF; Lukin, J; Ramos, AJ; Rossi, AR; Villarreal, A, 2013) |
| "After global cerebral ischemia, delayed cell death is observed in the thalamic reticular nucleus but the mechanisms involved are not well described." | 1.35 | Endonuclease G expression in thalamic reticular nucleus after global cerebral ischemia. ( Diemer, NH; Nielsen, M; Zimmer, J, 2008) |
| " For this purpose we conducted a dose-response study at concentrations of AMPA between 0." | 1.35 | Pattern of injury with a graded excitotoxic insult and ensuing chronic medial septal damage in the rat brain. ( Andrés, N; Batlle, M; Mahy, N; Malpesa, Y; Prats, A; Pugliese, M; Rodríguez, MJ, 2009) |
| "Quisqualic acid was injected into the right nucleus basalis of rats." | 1.31 | Brain inflammatory reaction in an animal model of neuronal degeneration and its modulation by an anti-inflammatory drug: implication in Alzheimer's disease. ( Casamenti, F; Pepeu, G; Prosperi, C; Scali, C; Vannucchi, MG, 2000) |
| "Vigabatrin has been recommended as a treatment for some forms of childhood epilepsy; therefore, further studies are needed to assess the risks in children." | 1.30 | Low-dose vigabatrin (gamma-vinyl GABA)-induced damage in the immature rat brain. ( Del Bigio, MR; Seshia, SS; Sidhu, RS; Tuor, UI, 1997) |
| "Tat-injected brains also exhibited astrocytosis, apoptotic cells, and ventricular enlargement 7 days following the last injection." | 1.30 | Intraventricular injection of human immunodeficiency virus type 1 (HIV-1) tat protein causes inflammation, gliosis, apoptosis, and ventricular enlargement. ( Del Bigio, MR; Jones, M; Nath, A; Olafson, K; Peeling, J, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (14.71) | 18.2507 |
| 2000's | 11 (32.35) | 29.6817 |
| 2010's | 14 (41.18) | 24.3611 |
| 2020's | 4 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| van den Berg, M | 1 |
| Adhikari, MH | 1 |
| Verschuuren, M | 1 |
| Pintelon, I | 1 |
| Vasilkovska, T | 1 |
| Van Audekerke, J | 1 |
| Missault, S | 1 |
| Heymans, L | 1 |
| Ponsaerts, P | 1 |
| De Vos, WH | 1 |
| Van der Linden, A | 1 |
| Keliris, GA | 1 |
| Verhoye, M | 1 |
| Nam, MH | 1 |
| Ko, HY | 1 |
| Kim, D | 1 |
| Lee, S | 1 |
| Park, YM | 1 |
| Hyeon, SJ | 1 |
| Won, W | 1 |
| Chung, JI | 1 |
| Kim, SY | 1 |
| Jo, HH | 1 |
| Oh, KT | 1 |
| Han, YE | 1 |
| Lee, GH | 1 |
| Ju, YH | 1 |
| Lee, H | 2 |
| Kim, H | 1 |
| Heo, J | 1 |
| Bhalla, M | 1 |
| Kim, KJ | 1 |
| Kwon, J | 1 |
| Stein, TD | 1 |
| Kong, M | 1 |
| Lee, SE | 1 |
| Oh, SJ | 1 |
| Chun, JH | 1 |
| Park, MA | 1 |
| Park, KD | 1 |
| Ryu, H | 1 |
| Yun, M | 1 |
| Lee, CJ | 1 |
| Drew, VJ | 1 |
| Park, M | 1 |
| Kim, T | 1 |
| Gu, Y | 1 |
| Wu, H | 1 |
| Wang, T | 1 |
| Yu, S | 1 |
| Han, Z | 1 |
| Zhang, W | 1 |
| Mu, L | 1 |
| Wang, H | 2 |
| Na, M | 1 |
| Lin, Z | 1 |
| Zawaski, JA | 1 |
| Sabek, OM | 1 |
| Voicu, H | 1 |
| Eastwood Leung, HC | 1 |
| Gaber, MW | 1 |
| Ramírez-Sánchez, J | 1 |
| Pires, ENS | 1 |
| Meneghetti, A | 1 |
| Hansel, G | 1 |
| Nuñez-Figueredo, Y | 1 |
| Pardo-Andreu, GL | 1 |
| Ochoa-Rodríguez, E | 1 |
| Verdecia-Reyes, Y | 1 |
| Delgado-Hernández, R | 1 |
| Salbego, C | 1 |
| Souza, DO | 1 |
| Al-Hazmi, MA | 1 |
| Rawi, SM | 1 |
| Arafa, NM | 1 |
| Wagas, A | 1 |
| Montasser, AO | 1 |
| Mori, F | 1 |
| Nisticò, R | 1 |
| Mandolesi, G | 1 |
| Piccinin, S | 1 |
| Mango, D | 1 |
| Kusayanagi, H | 1 |
| Berretta, N | 1 |
| Bergami, A | 1 |
| Gentile, A | 1 |
| Musella, A | 1 |
| Nicoletti, CG | 1 |
| Nicoletti, F | 1 |
| Buttari, F | 1 |
| Mercuri, NB | 1 |
| Martino, G | 1 |
| Furlan, R | 1 |
| Centonze, D | 1 |
| Rossi, AR | 1 |
| Angelo, MF | 1 |
| Villarreal, A | 1 |
| Lukin, J | 1 |
| Ramos, AJ | 1 |
| Khan, N | 1 |
| Woodruff, TM | 1 |
| Smith, MT | 1 |
| Silva, GA | 1 |
| Pradella, F | 1 |
| Moraes, A | 1 |
| Farias, A | 1 |
| dos Santos, LM | 1 |
| de Oliveira, AL | 1 |
| De Luca, C | 1 |
| Savarese, L | 1 |
| Colangelo, AM | 1 |
| Bianco, MR | 1 |
| Cirillo, G | 1 |
| Alberghina, L | 1 |
| Papa, M | 1 |
| Bevilaqua, MC | 1 |
| Andrade-da-Costa, BL | 1 |
| Fleming, RL | 1 |
| Dias, GP | 1 |
| da Silveirada Luz, AC | 1 |
| Nardi, AE | 1 |
| de Mello, FG | 1 |
| Gardino, PF | 1 |
| Calaza, KC | 1 |
| Robel, S | 1 |
| Sontheimer, H | 1 |
| Yelkenli, İH | 1 |
| Ulupinar, E | 1 |
| Korkmaz, OT | 1 |
| Şener, E | 1 |
| Kuş, G | 1 |
| Filiz, Z | 1 |
| Tunçel, N | 1 |
| Nielsen, M | 1 |
| Zimmer, J | 1 |
| Diemer, NH | 1 |
| Béldi, M | 1 |
| Takács, J | 1 |
| Bárdos, G | 1 |
| Világi, I | 1 |
| Sargin, D | 1 |
| Hassouna, I | 1 |
| Sperling, S | 1 |
| Sirén, AL | 1 |
| Ehrenreich, H | 1 |
| Rodríguez, MJ | 1 |
| Prats, A | 1 |
| Malpesa, Y | 1 |
| Andrés, N | 1 |
| Pugliese, M | 1 |
| Batlle, M | 1 |
| Mahy, N | 1 |
| Milanese, M | 1 |
| Zappettini, S | 1 |
| Jacchetti, E | 1 |
| Bonifacino, T | 1 |
| Cervetto, C | 1 |
| Usai, C | 1 |
| Bonanno, G | 1 |
| Dinocourt, C | 1 |
| Aungst, S | 1 |
| Yang, K | 1 |
| Thompson, SM | 1 |
| Musgrave, T | 1 |
| Benson, C | 1 |
| Wong, G | 1 |
| Browne, I | 1 |
| Tenorio, G | 1 |
| Rauw, G | 1 |
| Baker, GB | 1 |
| Kerr, BJ | 1 |
| McCormack, AL | 1 |
| Thiruchelvam, M | 1 |
| Manning-Bog, AB | 1 |
| Thiffault, C | 1 |
| Langston, JW | 1 |
| Cory-Slechta, DA | 1 |
| Di Monte, DA | 1 |
| Kuhn, SA | 1 |
| van Landeghem, FK | 1 |
| Zacharias, R | 1 |
| Färber, K | 1 |
| Rappert, A | 1 |
| Pavlovic, S | 1 |
| Hoffmann, A | 1 |
| Nolte, C | 1 |
| Kettenmann, H | 1 |
| Tateishi, N | 1 |
| Shimoda, T | 1 |
| Manako, J | 1 |
| Katsumata, S | 1 |
| Shinagawa, R | 1 |
| Ohno, H | 1 |
| Valencia, I | 1 |
| Legido, A | 1 |
| Yelin, K | 1 |
| Khurana, D | 1 |
| Kothare, SV | 1 |
| Katsetos, CD | 1 |
| Franklin, SL | 1 |
| Love, S | 1 |
| Greene, JR | 1 |
| Betmouni, S | 1 |
| Araneda, S | 1 |
| Silva-Barrat, C | 1 |
| Menini, C | 1 |
| Naquet, R | 1 |
| Sidhu, RS | 1 |
| Del Bigio, MR | 2 |
| Tuor, UI | 1 |
| Seshia, SS | 1 |
| Guentchev, M | 1 |
| Hainfellner, JA | 1 |
| Trabattoni, GR | 1 |
| Budka, H | 1 |
| MacGregor, DG | 1 |
| Graham, DI | 1 |
| Stone, TW | 1 |
| Jones, M | 1 |
| Olafson, K | 1 |
| Peeling, J | 1 |
| Nath, A | 1 |
| Scali, C | 1 |
| Prosperi, C | 1 |
| Vannucchi, MG | 1 |
| Pepeu, G | 1 |
| Casamenti, F | 1 |
| Tighilet, B | 1 |
| Lacour, M | 1 |
1 review available for gamma-aminobutyric acid and Astrocytosis
| Article | Year |
|---|---|
Glia as drivers of abnormal neuronal activity.
Topics: Animals; Astrocytes; Central Nervous System Neoplasms; Epilepsy; gamma-Aminobutyric Acid; Gliosis; H | 2016 |
33 other studies available for gamma-aminobutyric acid and Astrocytosis
| Article | Year |
|---|---|
Altered basal forebrain function during whole-brain network activity at pre- and early-plaque stages of Alzheimer's disease in TgF344-AD rats.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Basal Forebrain; Cholinergic Agents; Disease Mode | 2022 |
Visualizing reactive astrocyte-neuron interaction in Alzheimer's disease using 11C-acetate and 18F-FDG.
Topics: Alzheimer Disease; Animals; Astrocytes; Brain; Carbon Radioisotopes; Fluorodeoxyglucose F18; gamma-A | 2023 |
GABA-Positive Astrogliosis in Sleep-Promoting Areas Associated with Sleep Disturbance in 5XFAD Mice.
Topics: Alzheimer Disease; Animals; Electroencephalography; gamma-Aminobutyric Acid; Gliosis; Male; Mice; Sl | 2023 |
Profiling Analysis of Circular RNA and mRNA in Human Temporal Lobe Epilepsy with Hippocampal Sclerosis ILAE Type 1.
Topics: Centromere Protein A; Chloride Channels; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Gliosis; | 2022 |
Effect of Brain Tumor Presence During Radiation on Tissue Toxicity: Transcriptomic and Metabolic Changes.
Topics: Allografts; Animals; Biopsy; Brain; Brain Neoplasms; gamma-Aminobutyric Acid; Gene Expression Profil | 2017 |
JM-20 Treatment After MCAO Reduced Astrocyte Reactivity and Neuronal Death on Peri-infarct Regions of the Rat Brain.
Topics: Animals; Astrocytes; Benzodiazepines; Brain; Brain Infarction; CA3 Region, Hippocampal; Cell Death; | 2019 |
The potent effects of ginseng root extract and memantine on cognitive dysfunction in male albino rats.
Topics: Acetylcholinesterase; Animals; Brain; Dopamine; Dose-Response Relationship, Drug; gamma-Aminobutyric | 2015 |
Interleukin-1β promotes long-term potentiation in patients with multiple sclerosis.
Topics: Adolescent; Adult; Animals; Encephalomyelitis, Autoimmune, Experimental; Female; gamma-Aminobutyric | 2014 |
Gabapentin administration reduces reactive gliosis and neurodegeneration after pilocarpine-induced status epilepticus.
Topics: Amines; Animals; Astrocytes; Cyclohexanecarboxylic Acids; Electroencephalography; Gabapentin; gamma- | 2013 |
Establishment and characterization of an optimized mouse model of multiple sclerosis-induced neuropathic pain using behavioral, pharmacologic, histologic and immunohistochemical methods.
Topics: Amines; Amitriptyline; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cyclohexanecarboxyli | 2014 |
Impact of pregabalin treatment on synaptic plasticity and glial reactivity during the course of experimental autoimmune encephalomyelitis.
Topics: Animals; Calcium-Binding Proteins; Cytokines; Disease Progression; Encephalomyelitis, Autoimmune, Ex | 2014 |
Astrocytes and Microglia-Mediated Immune Response in Maladaptive Plasticity is Differently Modulated by NGF in the Ventral Horn of the Spinal Cord Following Peripheral Nerve Injury.
Topics: Animals; Antigens, Nuclear; Astrocytes; Biomarkers; Calcium-Binding Proteins; Chromatography, High P | 2016 |
Retinal development impairment and degenerative alterations in adult rats subjected to post-natal malnutrition.
Topics: Age Factors; Animals; Animals, Newborn; Cell Count; Cell Death; Cell Proliferation; Disease Models, | 2015 |
Modulation of Corpus Striatal Neurochemistry by Astrocytes and Vasoactive Intestinal Peptide (VIP) in Parkinsonian Rats.
Topics: Animals; Astrocytes; Corpus Striatum; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glio | 2016 |
Endonuclease G expression in thalamic reticular nucleus after global cerebral ischemia.
Topics: Active Transport, Cell Nucleus; Animals; Apoptosis; Astrocytes; Biomarkers; Brain Infarction; Brain | 2008 |
Retardation in somatosensory cortex development induced by postnatal BrdU treatment in mice.
Topics: Action Potentials; Aging; Animals; Animals, Newborn; Antimetabolites; Biomarkers; Bromodeoxyuridine; | 2008 |
Uncoupling of neurodegeneration and gliosis in a murine model of juvenile cortical lesion.
Topics: Animals; Astrocytes; Atrophy; Brain; Brain Injuries; Cold Temperature; Cyclic Nucleotide Phosphodies | 2009 |
Pattern of injury with a graded excitotoxic insult and ensuing chronic medial septal damage in the rat brain.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Atroph | 2009 |
In vitro activation of GAT1 transporters expressed in spinal cord gliosomes stimulates glutamate release that is abnormally elevated in the SOD1/G93A(+) mouse model of amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Calcium; Chelating Agents; Disease Models, Animal; Dose-Resp | 2010 |
Homeostatic increase in excitability in area CA1 after Schaffer collateral transection in vivo.
Topics: Action Potentials; Animals; CA1 Region, Hippocampal; Denervation; Fluoresceins; gamma-Aminobutyric A | 2011 |
The MAO inhibitor phenelzine improves functional outcomes in mice with experimental autoimmune encephalomyelitis (EAE).
Topics: Affect; Animals; Anterior Horn Cells; Brain Chemistry; Chromatography, High Pressure Liquid; Disease | 2011 |
Environmental risk factors and Parkinson's disease: selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat.
Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Biomarkers; Dopamine; Environm | 2002 |
Microglia express GABA(B) receptors to modulate interleukin release.
Topics: Animals; Animals, Newborn; Axotomy; Calcium Signaling; Cells, Cultured; Central Nervous System; Faci | 2004 |
Relevance of astrocytic activation to reductions of astrocytic GABAA receptors.
Topics: Aging; Animals; Animals, Newborn; Astrocytes; Biomarkers; Brain Ischemia; Cell Communication; Cell M | 2006 |
Anomalous inhibitory circuits in cortical tubers of human tuberous sclerosis complex associated with refractory epilepsy: aberrant expression of parvalbumin and calbindin-D28k in dysplastic cortex.
Topics: Adolescent; Adult; Biomarkers; Calbindin 1; Calbindins; Calcium; Calcium-Binding Proteins; Cerebral | 2006 |
Loss of Perineuronal Net in ME7 Prion Disease.
Topics: Animals; Disease Models, Animal; Disease Progression; Encephalitis; Extracellular Matrix; Female; ga | 2008 |
High expression of noradrenaline, choline acetyltransferase and glial fibrillary acidic protein in the epileptic focus consecutive to GABA withdrawal. An immunocytochemical study.
Topics: Animals; Cholecystokinin; Choline O-Acetyltransferase; Epilepsy; gamma-Aminobutyric Acid; Glial Fibr | 1994 |
Low-dose vigabatrin (gamma-vinyl GABA)-induced damage in the immature rat brain.
Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Apoptosis; Brain; Brain Damage, Chronic; Enz | 1997 |
Distribution of parvalbumin-immunoreactive neurons in brain correlates with hippocampal and temporal cortical pathology in Creutzfeldt-Jakob disease.
Topics: Adult; Aged; Aged, 80 and over; Astrocytes; Calbindin 1; Calbindins; Creutzfeldt-Jakob Syndrome; Fem | 1997 |
The attenuation of kainate-induced neurotoxicity by chlormethiazole and its enhancement by dizocilpine, muscimol, and adenosine receptor agonists.
Topics: Adenosine; Animals; Body Temperature; Chlormethiazole; Dizocilpine Maleate; Drug Synergism; Drug The | 1997 |
Intraventricular injection of human immunodeficiency virus type 1 (HIV-1) tat protein causes inflammation, gliosis, apoptosis, and ventricular enlargement.
Topics: Animals; Apoptosis; Aspartic Acid; Astrocytes; Basal Ganglia; Biotin; Cerebral Cortex; Cerebral Vent | 1998 |
Brain inflammatory reaction in an animal model of neuronal degeneration and its modulation by an anti-inflammatory drug: implication in Alzheimer's disease.
Topics: Acetylcholine; Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Choline O-Acetyl | 2000 |
Gamma amino butyric acid (GABA) immunoreactivity in the vestibular nuclei of normal and unilateral vestibular neurectomized cats.
Topics: Adaptation, Physiological; Animals; Astrocytes; Cats; Cell Count; Functional Laterality; gamma-Amino | 2001 |