Page last updated: 2024-10-16

gamma-aminobutyric acid and Astrocytoma, Grade IV

gamma-aminobutyric acid has been researched along with Astrocytoma, Grade IV in 13 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Research Excerpts

ExcerptRelevanceReference
"Recent studies suggest that seizures at the onset of GBM could be a possible favorable independent prognostic factor in patients."2.82Epileptogenesis and Tumorigenesis in Glioblastoma: Which Relationship? ( Biagini, G; Cavallieri, F; Cozzi, S; Giaccherini, L; Pisanello, A; Rizzi, R; Rossi, J; Russo, M; Valzania, F, 2022)
"In the renal cell carcinoma, in contrast with GBM, (13) C multiplets of γ-aminobutyric acid (GABA) differed from its precursor glutamate, suggesting that GABA did not derive from a common glutamate precursor pool."1.38Glucose metabolism via the pentose phosphate pathway, glycolysis and Krebs cycle in an orthotopic mouse model of human brain tumors. ( Bachoo, RM; Cho, SK; Choi, C; Deberardinis, RJ; Good, LB; Hatanpaa, KJ; Jindal, A; Kapur, P; Maher, EA; Malloy, CR; Marin-Valencia, I; Mashimo, T; Mickey, B; Pascual, JM; Raisanen, J; Rakheja, D; Sun, X; Takahashi, M; Togao, O; Vemireddy, V, 2012)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19902 (15.38)18.7374
1990's1 (7.69)18.2507
2000's2 (15.38)29.6817
2010's5 (38.46)24.3611
2020's3 (23.08)2.80

Authors

AuthorsStudies
Rossi, J1
Cavallieri, F1
Biagini, G1
Rizzi, R1
Russo, M1
Cozzi, S1
Giaccherini, L1
Pisanello, A1
Valzania, F1
Rich, LJ1
Bagga, P1
Wilson, NE1
Schnall, MD1
Detre, JA1
Haris, M1
Reddy, R1
Palma, A1
Grande, S1
Ricci-Vitiani, L1
Luciani, AM1
Buccarelli, M1
Biffoni, M1
Dini, V1
Cirrone, GAP1
Ciocca, M1
Guidoni, L1
Pallini, R1
Viti, V1
Rosi, A1
Corona-Ramos, JN1
Déciga-Campos, M1
Romero-Piña, M1
Medina, LA1
Martínez-Racine, I1
Jaramillo-Morales, OA1
García-López, P1
López-Muñoz, FJ1
Yamaguchi, K1
Kumakura, S1
Someya, A1
Iseki, M1
Inada, E1
Nagaoka, I1
Geier, EG1
Schlessinger, A1
Fan, H1
Gable, JE1
Irwin, JJ1
Sali, A1
Giacomini, KM1
Babateen, O1
Jin, Z1
Bhandage, A1
Korol, SV1
Westermark, B1
Forsberg Nilsson, K1
Uhrbom, L1
Smits, A1
Birnir, B1
Kang, JS1
Krakow, K1
Roggendorf, J1
Steinmetz, H1
Hilker, R1
Habela, CW1
Ernest, NJ1
Swindall, AF1
Sontheimer, H1
Marin-Valencia, I1
Cho, SK1
Rakheja, D1
Hatanpaa, KJ1
Kapur, P1
Mashimo, T1
Jindal, A1
Vemireddy, V1
Good, LB1
Raisanen, J1
Sun, X1
Mickey, B1
Choi, C1
Takahashi, M1
Togao, O1
Pascual, JM1
Deberardinis, RJ1
Maher, EA1
Malloy, CR1
Bachoo, RM1
Labrakakis, C1
Patt, S1
Hartmann, J1
Kettenmann, H1
Lefauconnier, JM1
Portemer, C1
Chatagner, F1
Haglid, KG1
Hamberger, A1
Carlsson, CA1
Lindgren, S1
Stavrou, D1
Sourander, P1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Treatment Development of Triheptanoin for Glucose Transporter Type I Deficiency[NCT02021526]Phase 1/Phase 20 participants (Actual)Interventional2015-12-31Withdrawn (stopped due to NIH funding resulted in new clinical trial)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for gamma-aminobutyric acid and Astrocytoma, Grade IV

ArticleYear
Epileptogenesis and Tumorigenesis in Glioblastoma: Which Relationship?
    Medicina (Kaunas, Lithuania), 2022, Sep-26, Volume: 58, Issue:10

    Topics: Aquaporins; Brain Neoplasms; Cell Transformation, Neoplastic; gamma-Aminobutyric Acid; Glioblastoma;

2022

Other Studies

12 other studies available for gamma-aminobutyric acid and Astrocytoma, Grade IV

ArticleYear
    Nature biomedical engineering, 2020, Volume: 4, Issue:3

    Topics: Animals; Brain; Brain Mapping; Cell Line, Tumor; Diagnostic Imaging; gamma-Aminobutyric Acid; Gliobl

2020
Different Mechanisms Underlie the Metabolic Response of GBM Stem-Like Cells to Ionizing Radiation: Biological and MRS Studies on Effects of Photons and Carbon Ions.
    International journal of molecular sciences, 2020, Jul-21, Volume: 21, Issue:14

    Topics: Brain Neoplasms; Cell Line, Tumor; G2 Phase Cell Cycle Checkpoints; gamma-Aminobutyric Acid; Gliobla

2020
The Effect of Gabapentin and Tramadol in Cancer Pain Induced by Glioma Cell in Rat Femur.
    Drug development research, 2017, Volume: 78, Issue:5

    Topics: Amines; Analgesics; Animals; Bone Neoplasms; Brain Neoplasms; Cancer Pain; Cell Line, Tumor; Cell Su

2017
Anti‑inflammatory actions of gabapentin and pregabalin on the substance P‑induced mitogen‑activated protein kinase activation in U373 MG human glioblastoma astrocytoma cells.
    Molecular medicine reports, 2017, Volume: 16, Issue:5

    Topics: Amines; Anti-Inflammatory Agents; Astrocytoma; Cell Line, Tumor; Cyclohexanecarboxylic Acids; Gabape

2017
Structure-based ligand discovery for the Large-neutral Amino Acid Transporter 1, LAT-1.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Apr-02, Volume: 110, Issue:14

    Topics: Amines; Analysis of Variance; Blood-Brain Barrier; Cell Line, Tumor; Crystallography, X-Ray; Cyclohe

2013
Etomidate, propofol and diazepam potentiate GABA-evoked GABAA currents in a cell line derived from human glioblastoma.
    European journal of pharmacology, 2015, Feb-05, Volume: 748

    Topics: Anesthetics, General; Cell Line, Tumor; Diazepam; Drug Synergism; Electrophysiological Phenomena; Et

2015
Botulinum toxin treatment of epilepsia partialis continua.
    Movement disorders : official journal of the Movement Disorder Society, 2009, Jan-15, Volume: 24, Issue:1

    Topics: Anticonvulsants; Botulinum Toxins, Type A; Epilepsia Partialis Continua; Fructose; gamma-Aminobutyri

2009
Chloride accumulation drives volume dynamics underlying cell proliferation and migration.
    Journal of neurophysiology, 2009, Volume: 101, Issue:2

    Topics: Acetates; Analysis of Variance; Bumetanide; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cel

2009
Glucose metabolism via the pentose phosphate pathway, glycolysis and Krebs cycle in an orthotopic mouse model of human brain tumors.
    NMR in biomedicine, 2012, Volume: 25, Issue:10

    Topics: Animals; Brain Neoplasms; Carcinoma, Renal Cell; Citric Acid Cycle; Disease Models, Animal; gamma-Am

2012
Functional GABA(A) receptors on human glioma cells.
    The European journal of neuroscience, 1998, Volume: 10, Issue:1

    Topics: Anti-Bacterial Agents; Calcium; Calcium Channel Blockers; Flunitrazepam; GABA Agonists; GABA Modulat

1998
Free amino acids and related substances in human glial tumours and in fetal brain: comparison with normal adult brain.
    Brain research, 1976, Nov-19, Volume: 117, Issue:1

    Topics: Adult; Age Factors; Aged; Amino Acids; Brain Chemistry; Brain Neoplasms; Female; Fetus; gamma-Aminob

1976
Glial cell characteristics in bulk-prepared cell fractions from human brain tumours.
    Acta neuropathologica, 1977, Nov-28, Volume: 40, Issue:3

    Topics: Astrocytoma; Brain Neoplasms; Cell Separation; Centrifugation, Density Gradient; gamma-Aminobutyric

1977