gamma-aminobutyric acid has been researched along with Asthma in 13 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the changes in plasma substance P (SP) and calcitonin gene-related peptide (CGRP) levels in children with acute asthma before and after gamma-aminobutyric acid (GABA) treatment." | 9.17 | [Effect of gamma-aminobutyric acid treatment on plasma substance P and calcitonin gene-related peptide levels in children with asthma]. ( Guo, SC; Wang, QY; Xu, CW; Zheng, ZW, 2013) |
| "To study the changes in plasma substance P (SP) and calcitonin gene-related peptide (CGRP) levels in children with acute asthma before and after gamma-aminobutyric acid (GABA) treatment." | 5.17 | [Effect of gamma-aminobutyric acid treatment on plasma substance P and calcitonin gene-related peptide levels in children with asthma]. ( Guo, SC; Wang, QY; Xu, CW; Zheng, ZW, 2013) |
| "In vivo, mice were sensitized and challenged by ovalbumin (OVA) to induce asthma." | 3.96 | Monocyte chemotactic protein-inducing protein 1 negatively regulating asthmatic airway inflammation and mucus hypersecretion involving γ-aminobutyric acid type A receptor signaling pathway in vivo and in vitro. ( Chen, ZH; Dai, GM; Deng, HJ; Mao, RL; Ran, YJ; Wang, JJ; Zhu, T, 2020) |
| " The expression of GAD in the cytosol and GABAARs in the apical membranes of airway epithelial cells increased markedly when mice were sensitized and then challenged with ovalbumin, an approach for inducing allergic asthmatic reactions." | 3.74 | A GABAergic system in airway epithelium is essential for mucus overproduction in asthma. ( Fan, Y; Hirota, JA; Inman, MD; Ju, W; Kelly, MM; Li, J; Liu, M; Lu, WY; O'Byrne, PM; Orser, B; Wang, S; Xiang, YY; Yang, X; Ye, B, 2007) |
| "Gamma-aminobutyric acid (GABA) is an important neurotransmitter that, through the subtype A GABA receptor (GABAAR), induces inhibition in the adult brain." | 1.34 | A GABAergic system in airway epithelium is essential for mucus overproduction in asthma. ( Fan, Y; Hirota, JA; Inman, MD; Ju, W; Kelly, MM; Li, J; Liu, M; Lu, WY; O'Byrne, PM; Orser, B; Wang, S; Xiang, YY; Yang, X; Ye, B, 2007) |
| "Episodic airway obstruction and reversible bronchial hyperresponsiveness to non-specific irritants are the major symptoms of asthma." | 1.33 | Bronchial epilepsy or broncho-pulmonary hyper-excitability as a model of asthma pathogenesis. ( Graeme Shaw, D; Hoang, BX; Hoang, C; Levine, SA; Pham, P, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 6 (46.15) | 24.3611 |
| 2020's | 3 (23.08) | 2.80 |
| Authors | Studies |
|---|---|
| Perez-Zoghbi, JF | 1 |
| Sajorda, DR | 1 |
| Webb, DA | 1 |
| Arnold, LA | 1 |
| Emala, CW | 1 |
| Yocum, GT | 1 |
| Nayak, AP | 1 |
| An, SS | 1 |
| Dai, GM | 1 |
| Wang, JJ | 1 |
| Chen, ZH | 1 |
| Ran, YJ | 1 |
| Deng, HJ | 1 |
| Mao, RL | 1 |
| Zhu, T | 1 |
| Sui, P | 1 |
| Wiesner, DL | 1 |
| Xu, J | 1 |
| Zhang, Y | 1 |
| Lee, J | 1 |
| Van Dyken, S | 1 |
| Lashua, A | 1 |
| Yu, C | 1 |
| Klein, BS | 1 |
| Locksley, RM | 1 |
| Deutsch, G | 1 |
| Sun, X | 1 |
| Barrios, J | 1 |
| Kho, AT | 1 |
| Aven, L | 1 |
| Mitchel, JA | 1 |
| Park, JA | 1 |
| Randell, SH | 1 |
| Miller, LA | 1 |
| Tantisira, KG | 1 |
| Ai, X | 1 |
| Xu, CW | 1 |
| Guo, SC | 1 |
| Zheng, ZW | 1 |
| Wang, QY | 1 |
| Guihua, X | 1 |
| Shuyin, L | 1 |
| Jinliang, G | 1 |
| Wang, S | 2 |
| Lu, WY | 3 |
| Inman, MD | 2 |
| Komai, M | 1 |
| Tanaka, H | 1 |
| Nagao, K | 1 |
| Ishizaki, M | 1 |
| Kajiwara, D | 1 |
| Miura, T | 1 |
| Ohashi, H | 1 |
| Haba, T | 1 |
| Kawakami, K | 1 |
| Sawa, E | 1 |
| Yoshie, O | 1 |
| Inagaki, N | 1 |
| Nagai, H | 1 |
| Hoang, BX | 1 |
| Levine, SA | 1 |
| Graeme Shaw, D | 1 |
| Pham, P | 1 |
| Hoang, C | 1 |
| Xiang, YY | 1 |
| Liu, M | 1 |
| Hirota, JA | 1 |
| Li, J | 1 |
| Ju, W | 1 |
| Fan, Y | 1 |
| Kelly, MM | 1 |
| Ye, B | 1 |
| Orser, B | 1 |
| O'Byrne, PM | 1 |
| Yang, X | 1 |
| Corry, DB | 1 |
| Kheradmand, F | 1 |
1 review available for gamma-aminobutyric acid and Asthma
| Article | Year |
|---|---|
Gamma-aminobutyric acid nurtures allergic asthma.
Topics: Animals; Asthma; Bronchi; Epithelial Cells; gamma-Aminobutyric Acid; Humans; Models, Immunological; | 2009 |
1 trial available for gamma-aminobutyric acid and Asthma
| Article | Year |
|---|---|
[Effect of gamma-aminobutyric acid treatment on plasma substance P and calcitonin gene-related peptide levels in children with asthma].
Topics: Asthma; Calcitonin Gene-Related Peptide; Child; Child, Preschool; Female; gamma-Aminobutyric Acid; H | 2013 |
11 other studies available for gamma-aminobutyric acid and Asthma
| Article | Year |
|---|---|
Imidazobenzodiazepine PI320 Relaxes Mouse Peripheral Airways by Inhibiting Calcium Mobilization.
Topics: Animals; Asthma; Calcium; Calcium Signaling; Flumazenil; gamma-Aminobutyric Acid; Inositol; Ligands; | 2022 |
Anxiolytics for Bronchodilation: Refinements to GABA
Topics: Animals; Anti-Anxiety Agents; Asthma; Bronchodilator Agents; Calcium; GABA-A Receptor Agonists; gamm | 2022 |
Monocyte chemotactic protein-inducing protein 1 negatively regulating asthmatic airway inflammation and mucus hypersecretion involving γ-aminobutyric acid type A receptor signaling pathway in vivo and in vitro.
Topics: Animals; Asthma; Bronchoalveolar Lavage Fluid; gamma-Aminobutyric Acid; Inflammation; Mice; Mice, In | 2020 |
Pulmonary neuroendocrine cells amplify allergic asthma responses.
Topics: Animals; Asthma; Basic Helix-Loop-Helix Transcription Factors; Calcitonin Gene-Related Peptide; Cyto | 2018 |
Pulmonary Neuroendocrine Cells Secrete γ-Aminobutyric Acid to Induce Goblet Cell Hyperplasia in Primate Models.
Topics: Acute Lung Injury; Animals; Asthma; Bronchi; Disease Models, Animal; Epithelial Cells; gamma-Aminobu | 2019 |
Naringin Protects Ovalbumin-Induced Airway Inflammation in a Mouse Model of Asthma.
Topics: Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Antioxidants; Asthma; Bronchoalveolar Lava | 2016 |
A novel CC-chemokine receptor 3 antagonist, Ki19003, inhibits airway eosinophilia and subepithelial/peribronchial fibrosis induced by repeated antigen challenge in mice.
Topics: Airway Remodeling; Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Dose-Respo | 2010 |
The potential use of GABAergic drugs in the treatment of asthma.
Topics: Asthma; Bronchial Hyperreactivity; gamma-Aminobutyric Acid; Humans; Pharmaceutical Preparations; Sig | 2011 |
Bronchial epilepsy or broncho-pulmonary hyper-excitability as a model of asthma pathogenesis.
Topics: Airway Obstruction; Asthma; Bronchi; Bronchial Hyperreactivity; Cell Membrane; gamma-Aminobutyric Ac | 2006 |
A GABAergic system in airway epithelium is essential for mucus overproduction in asthma.
Topics: Animals; Asthma; Cells, Cultured; Female; gamma-Aminobutyric Acid; Humans; Mice; Mice, Inbred BALB C | 2007 |
A new link to airway obstruction in asthma.
Topics: Airway Obstruction; Asthma; gamma-Aminobutyric Acid; Humans; Mucus; Respiratory System; Signal Trans | 2007 |