gamma-aminobutyric acid has been researched along with Arthritis, Rheumatoid in 12 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study indicated that the Glutamine-Glutamate/GABA cycle played essential regulation roles in protective effect of THHE on rat RA following adjuvant-induced damage, and GLUD2 as an attractive target also provides great potential for development of therapy agents for rheumatoid arthritis and autoimmune diseases with less unfavorable tolerability profile." | 8.02 | Role of Glutamine-Glutamate/GABA cycle and potential target GLUD2 in alleviation of rheumatoid arthritis by Tripterygium hypoglaucum (levl.) Hutch based on metabolomics and molecular pharmacology. ( Guo, Y; Huang, S; Long, C; Qiao, X; Wang, Y; Yang, D; Yang, Y; Zhang, L; Zhang, X, 2021) |
| "This study indicated that the Glutamine-Glutamate/GABA cycle played essential regulation roles in protective effect of THHE on rat RA following adjuvant-induced damage, and GLUD2 as an attractive target also provides great potential for development of therapy agents for rheumatoid arthritis and autoimmune diseases with less unfavorable tolerability profile." | 4.02 | Role of Glutamine-Glutamate/GABA cycle and potential target GLUD2 in alleviation of rheumatoid arthritis by Tripterygium hypoglaucum (levl.) Hutch based on metabolomics and molecular pharmacology. ( Guo, Y; Huang, S; Long, C; Qiao, X; Wang, Y; Yang, D; Yang, Y; Zhang, L; Zhang, X, 2021) |
| "Current treatments for rheumatoid arthritis (RA) have long-term side effects such that new treatments are needed that can safely help manage the disease." | 1.37 | Oral GABA treatment downregulates inflammatory responses in a mouse model of rheumatoid arthritis. ( Dang, H; Kaufman, DL; Tian, J; Yong, J, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 6 (50.00) | 24.3611 |
| 2020's | 3 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Won, W | 1 |
| Choi, HJ | 1 |
| Yoo, JY | 1 |
| Kim, D | 1 |
| Kim, TY | 1 |
| Ju, Y | 1 |
| Park, KD | 1 |
| Lee, H | 1 |
| Jung, SY | 1 |
| Lee, CJ | 1 |
| Shan, Y | 1 |
| Zhao, J | 1 |
| Zheng, Y | 1 |
| Guo, S | 1 |
| Schrodi, SJ | 1 |
| He, D | 1 |
| Peña, J | 1 |
| Casas-Ferreira, AM | 1 |
| Morales-Tenorio, M | 1 |
| Moreno-Cordero, B | 1 |
| Pérez-Pavón, JL | 1 |
| Long, C | 1 |
| Yang, Y | 2 |
| Wang, Y | 1 |
| Zhang, X | 1 |
| Zhang, L | 1 |
| Huang, S | 1 |
| Yang, D | 1 |
| Qiao, X | 1 |
| Guo, Y | 1 |
| Regan, DW | 1 |
| Kashiwagi, D | 1 |
| Dougan, B | 1 |
| Sundsted, K | 1 |
| Mauck, K | 1 |
| Kurmann, PT | 1 |
| Van Linthoudt, D | 1 |
| So, AK | 1 |
| Christianson, CA | 1 |
| Corr, M | 1 |
| Firestein, GS | 1 |
| Mobargha, A | 1 |
| Yaksh, TL | 1 |
| Svensson, CI | 1 |
| Tian, J | 1 |
| Yong, J | 1 |
| Dang, H | 1 |
| Kaufman, DL | 1 |
| Lantos, PM | 1 |
| Jin, Z | 1 |
| Mendu, SK | 1 |
| Birnir, B | 1 |
| Dani, K | 1 |
| Ramachandran, R | 1 |
| Capell, HA | 1 |
| Madhok, R | 1 |
| Kelley, JM | 1 |
| Hughes, LB | 1 |
| Bridges, SL | 1 |
4 reviews available for gamma-aminobutyric acid and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Understanding the function of the GABAergic system and its potential role in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Humans; Inf | 2023 |
Update in perioperative medicine: practice changing evidence published in 2016.
Topics: Amines; Analgesics; Anticoagulants; Antipsychotic Agents; Arthritis, Rheumatoid; Blood Transfusion; | 2017 |
GABA is an effective immunomodulatory molecule.
Topics: Animals; Arthritis, Rheumatoid; Diabetes Mellitus, Type 1; gamma-Aminobutyric Acid; Humans; Mice; Mu | 2013 |
Does gamma-aminobutyric acid (GABA) influence the development of chronic inflammation in rheumatoid arthritis?
Topics: Animals; Arthritis, Rheumatoid; gamma-Aminobutyric Acid; Humans; Interleukin-1; Interleukin-6; Matri | 2008 |
8 other studies available for gamma-aminobutyric acid and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Inhibiting peripheral and central MAO-B ameliorates joint inflammation and cognitive impairment in rheumatoid arthritis.
Topics: Animals; Arthritis, Rheumatoid; Cells, Cultured; Cognitive Dysfunction; Fibroblasts; gamma-Aminobuty | 2022 |
Determination of polyamines and related compounds in saliva via in situ derivatization and microextraction by packed sorbents coupled to GC-MS.
Topics: Arthritis, Rheumatoid; Biosensing Techniques; Female; gamma-Aminobutyric Acid; Gas Chromatography-Ma | 2019 |
Role of Glutamine-Glutamate/GABA cycle and potential target GLUD2 in alleviation of rheumatoid arthritis by Tripterygium hypoglaucum (levl.) Hutch based on metabolomics and molecular pharmacology.
Topics: Animals; Arthritis, Rheumatoid; Female; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutami | 2021 |
Miller-Fisher syndrome in a patient with rheumatoid arthritis treated with adalimumab.
Topics: Adalimumab; Aged; Amines; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic A | 2009 |
Characterization of the acute and persistent pain state present in K/BxN serum transfer arthritis.
Topics: Activating Transcription Factor 3; Amines; Analgesics; Analysis of Variance; Animals; Arthritis, Rhe | 2010 |
Oral GABA treatment downregulates inflammatory responses in a mouse model of rheumatoid arthritis.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Collagen; gamma-Aminobutyric Acid; Immunogl | 2011 |
Chronic Lyme disease: the controversies and the science.
Topics: Amines; Analgesics; Anti-Bacterial Agents; Arthritis, Rheumatoid; Borrelia burgdorferi; Chronic Dise | 2011 |
Neuropathies in the rheumatoid patient: a case of the heavy hand.
Topics: Amines; Arthritis, Rheumatoid; Cyclohexanecarboxylic Acids; Electromyography; Female; Follow-Up Stud | 2005 |