gamma-aminobutyric acid has been researched along with Anterior Choroidal Artery Infarction in 39 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Excerpt | Relevance | Reference |
---|---|---|
"To determine the relative tolerability and efficacy of two newer antiepileptic drugs, lamotrigine (LTG) and gabapentin (GBP), as compared to carbamazepine (CBZ) in older patients with epilepsy." | 9.11 | New onset geriatric epilepsy: a randomized study of gabapentin, lamotrigine, and carbamazepine. ( Boardman, KD; Carter, GS; Collins, JF; Felicetta, J; Frederick, T; Marks, W; Pryor, F; Ramsay, RE; Rowan, AJ; Spitz, M; Tomyanovich, ML; Towne, A; Uthman, BM, 2005) |
"Compositions of phenibut with salicylic, nicotinic, and glutamic acids in subtotal and transient cerebral ischemia were found to have the most pronounced cerebroprotective effect in doses of 30, 50 and 50 mg/kg, respectively." | 8.31 | Experimental Substantiation of the Use of Phenibut Combinations with Salicylic, Nicotinic, and Glutamic Acids in Cerebral Ischemia. ( Monov, D; Pashanova, O, 2023) |
"We present 2 patients with severe and intractable central poststroke pain (CPSP) after right posterolateral thalamic infarcts who were successfully treated with zonisamide." | 7.72 | Successful use of zonisamide for central poststroke pain. ( Hashimoto, K; Takahashi, Y; Tsuji, S, 2004) |
"The effects of aniracetam, a cognition enhancer, on extracellular levels of glutamate (Glu), gamma-aminobutyric acid (GABA) and nitric oxide metabolites (NOx) were examined in the prefrontal cortex (PFC) and the basolateral amygdala (AMG) in stroke-prone spontaneously hypertensive rats (SHRSP) using in vivo microdialysis." | 7.71 | Aniracetam enhances glutamatergic transmission in the prefrontal cortex of stroke-prone spontaneously hypertensive rats. ( Matsumoto, M; Nakamura, K; Ohashi, S; Saito, H; Togashi, H; Ueno, K; Yoshioka, M, 2002) |
"GABA and Piracetam caused the improvement of the morphological state of cerebral infarction, due to intracarotid infusion of Arachidonic acid." | 7.68 | [Effects of GABA and piracetam on the development of experimental cerebral infarction in rats and platelet aggregation in patients with cerebrovascular disorders]. ( Amroian, EA; Balian, LS; Parsamian, LK; Vartazarian, ND, 1990) |
"The most common etiology was cerebral infarction." | 6.71 | New onset geriatric epilepsy: a randomized study of gabapentin, lamotrigine, and carbamazepine. ( Boardman, KD; Carter, GS; Collins, JF; Felicetta, J; Frederick, T; Marks, W; Pryor, F; Ramsay, RE; Rowan, AJ; Spitz, M; Tomyanovich, ML; Towne, A; Uthman, BM, 2005) |
"To determine the relative tolerability and efficacy of two newer antiepileptic drugs, lamotrigine (LTG) and gabapentin (GBP), as compared to carbamazepine (CBZ) in older patients with epilepsy." | 5.11 | New onset geriatric epilepsy: a randomized study of gabapentin, lamotrigine, and carbamazepine. ( Boardman, KD; Carter, GS; Collins, JF; Felicetta, J; Frederick, T; Marks, W; Pryor, F; Ramsay, RE; Rowan, AJ; Spitz, M; Tomyanovich, ML; Towne, A; Uthman, BM, 2005) |
"Compositions of phenibut with salicylic, nicotinic, and glutamic acids in subtotal and transient cerebral ischemia were found to have the most pronounced cerebroprotective effect in doses of 30, 50 and 50 mg/kg, respectively." | 4.31 | Experimental Substantiation of the Use of Phenibut Combinations with Salicylic, Nicotinic, and Glutamic Acids in Cerebral Ischemia. ( Monov, D; Pashanova, O, 2023) |
" In the present study, therefore, we aimed to elucidate whether BMSC express the neuron-specific gamma-aminobutyric acid (GABA) receptor when transplanted into brain that has been subjected to cerebral infarction." | 3.73 | Improved expression of gamma-aminobutyric acid receptor in mice with cerebral infarct and transplanted bone marrow stromal cells: an autoradiographic and histologic analysis. ( Hida, K; Iwasaki, Y; Kuroda, S; Ohnishi, T; Shichinohe, H; Tamagami, H; Yano, S, 2006) |
"We present 2 patients with severe and intractable central poststroke pain (CPSP) after right posterolateral thalamic infarcts who were successfully treated with zonisamide." | 3.72 | Successful use of zonisamide for central poststroke pain. ( Hashimoto, K; Takahashi, Y; Tsuji, S, 2004) |
"The effects of aniracetam, a cognition enhancer, on extracellular levels of glutamate (Glu), gamma-aminobutyric acid (GABA) and nitric oxide metabolites (NOx) were examined in the prefrontal cortex (PFC) and the basolateral amygdala (AMG) in stroke-prone spontaneously hypertensive rats (SHRSP) using in vivo microdialysis." | 3.71 | Aniracetam enhances glutamatergic transmission in the prefrontal cortex of stroke-prone spontaneously hypertensive rats. ( Matsumoto, M; Nakamura, K; Ohashi, S; Saito, H; Togashi, H; Ueno, K; Yoshioka, M, 2002) |
"GABA and Piracetam caused the improvement of the morphological state of cerebral infarction, due to intracarotid infusion of Arachidonic acid." | 3.68 | [Effects of GABA and piracetam on the development of experimental cerebral infarction in rats and platelet aggregation in patients with cerebrovascular disorders]. ( Amroian, EA; Balian, LS; Parsamian, LK; Vartazarian, ND, 1990) |
"Dopamine (DA), serotonin (5-HT), tryptophan (TRP), 5-hydroxyindole acetic acid (5-HIAA), and GABA were assayed spectrofluorometrically in various regions of 16 human post-mortem brains with acute and old cerebral infarction." | 3.66 | Changes of some putative neurotransmitters in human cerebral infarction. ( Jellinger, K; Kothbauer, P; Riederer, P, 1978) |
"The most common etiology was cerebral infarction." | 2.71 | New onset geriatric epilepsy: a randomized study of gabapentin, lamotrigine, and carbamazepine. ( Boardman, KD; Carter, GS; Collins, JF; Felicetta, J; Frederick, T; Marks, W; Pryor, F; Ramsay, RE; Rowan, AJ; Spitz, M; Tomyanovich, ML; Towne, A; Uthman, BM, 2005) |
"However 20-30% of patients with lacunar stroke worsen neurologically in hours or days after onset, reaching eventually an unexpectedly severe disability status." | 2.48 | Progressive lacunar stroke: review of mechanisms, prognostic features, and putative treatments. ( Del Bene, A; Inzitari, D; Lamassa, M; Palumbo, V; Piccardi, B; Saia, V, 2012) |
"Persistent hiccups have been reported to occur occasionally during rehabilitation hospitalizations." | 2.44 | Persistent hiccups during rehabilitation hospitalization: three case reports and review of the literature. ( Browne, BA; Schuchmann, JA, 2007) |
"Cerebral ischemia is the leading cause for long-term disability and mortality in adults due to massive neuronal death." | 1.91 | Targeting the interaction of GABA ( Balakrishnan, K; Benke, D; Bhat, MA; Ganley, RP; Hleihil, M; Klohs, J; Vaas, M; Zeilhofer, HU, 2023) |
"TTC staining was used to detect cerebral infarction volume, and the brain water content of rats in each group was determined by wet and dry weight method." | 1.91 | [Effects of Governor Vessel electroacupuncture on chloridion homeostasis in the cortex of rats with limb spasm after cerebral ischemia-reperfusion]. ( Guo, J; Li, JW; Li, RQ; Mei, JJ; Wang, YY; Zhang, JY; Zhang, LH, 2023) |
"This study utilized a cerebral ischemia reperfusion (IR) model to produce a stressful brain condition that highlights the possible involvement of a hippocampal GC/pERK1/2/BDNF pathway in the resulting sexual consequences of this ailment." | 1.72 | Insights into the role of pERK1/2 signaling in post-cerebral ischemia reperfusion sexual dysfunction in rats. ( El-Sahar, AE; Khattab, MA; Mohammed, RA; Saad, MA; Sayed, RH, 2022) |
"Stroke is a leading cause of disability, but no pharmacological therapy is currently available for promoting recovery." | 1.36 | Reducing excessive GABA-mediated tonic inhibition promotes functional recovery after stroke. ( Carmichael, ST; Clarkson, AN; Huang, BS; Macisaac, SE; Mody, I, 2010) |
"Malignant cerebral infarction (MaCI) treated with mechanical ventilation, mannitol, or barbiturates has a mortality of about 80% and survivors show severe disability." | 1.33 | Prolonged moderate hypothermia in massive hemispheric infarction: clinical experience. ( Escuret, E; Heroum, C; Milhaud, D; Thouvenot, E, 2005) |
"In 49 patients with various neurological disorders plasma and CSF gamma-aminobutyric acid (GABA) concentrations were determined by radioreceptor assay." | 1.26 | Plasma and cerebrospinal fluid gamma-aminobutyric acid in neurological disorders. ( Löscher, W; Schmidt, D, 1982) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 10 (25.64) | 18.7374 |
1990's | 8 (20.51) | 18.2507 |
2000's | 8 (20.51) | 29.6817 |
2010's | 9 (23.08) | 24.3611 |
2020's | 4 (10.26) | 2.80 |
Authors | Studies |
---|---|
Balakrishnan, K | 1 |
Hleihil, M | 1 |
Bhat, MA | 1 |
Ganley, RP | 1 |
Vaas, M | 1 |
Klohs, J | 1 |
Zeilhofer, HU | 1 |
Benke, D | 1 |
Mohammed, RA | 1 |
Sayed, RH | 1 |
El-Sahar, AE | 1 |
Khattab, MA | 1 |
Saad, MA | 1 |
Monov, D | 1 |
Pashanova, O | 1 |
Wang, YY | 1 |
Li, RQ | 1 |
Li, JW | 1 |
Mei, JJ | 1 |
Zhang, LH | 1 |
Zhang, JY | 1 |
Guo, J | 1 |
Zhang, M | 1 |
Sun, X | 1 |
Guo, F | 1 |
Gong, Y | 1 |
Xu, L | 2 |
Kim, JB | 1 |
Yu, S | 1 |
Pistoia, F | 1 |
Sarà, M | 1 |
Clarkson, AN | 1 |
Huang, BS | 1 |
Macisaac, SE | 1 |
Mody, I | 1 |
Carmichael, ST | 2 |
Staley, K | 1 |
Kamiya, T | 1 |
Abe, K | 1 |
Del Bene, A | 1 |
Palumbo, V | 1 |
Lamassa, M | 1 |
Saia, V | 1 |
Piccardi, B | 1 |
Inzitari, D | 1 |
Song, WT | 1 |
Lin, CR | 1 |
Ren, JX | 1 |
Liu, JX | 1 |
Yao, MJ | 1 |
Wang, GR | 1 |
Takahashi, Y | 1 |
Hashimoto, K | 1 |
Tsuji, S | 1 |
Milhaud, D | 1 |
Thouvenot, E | 1 |
Heroum, C | 1 |
Escuret, E | 1 |
Rowan, AJ | 1 |
Ramsay, RE | 1 |
Collins, JF | 1 |
Pryor, F | 1 |
Boardman, KD | 1 |
Uthman, BM | 1 |
Spitz, M | 1 |
Frederick, T | 1 |
Towne, A | 1 |
Carter, GS | 1 |
Marks, W | 1 |
Felicetta, J | 1 |
Tomyanovich, ML | 1 |
Kang, TH | 1 |
Oh, HR | 1 |
Jung, SM | 1 |
Ryu, JH | 1 |
Park, MW | 1 |
Park, YK | 1 |
Kim, SY | 1 |
Shichinohe, H | 1 |
Kuroda, S | 1 |
Yano, S | 1 |
Ohnishi, T | 1 |
Tamagami, H | 1 |
Hida, K | 1 |
Iwasaki, Y | 1 |
Schuchmann, JA | 1 |
Browne, BA | 1 |
Kharlamov, EA | 1 |
Downey, KL | 1 |
Jukkola, PI | 1 |
Grayson, DR | 1 |
Kelly, KM | 1 |
Jellinger, K | 3 |
Riederer, P | 3 |
Kameyama, M | 1 |
Kuroda, H | 1 |
Schmidt, D | 1 |
Löscher, W | 1 |
Neumann-Haefelin, T | 2 |
Hagemann, G | 1 |
Witte, OW | 2 |
Lyden, PD | 1 |
Lonzo, L | 1 |
Aihara, N | 2 |
Mizukawa, K | 1 |
Koide, K | 2 |
Mabe, H | 1 |
Nishino, H | 2 |
Kumazaki, M | 1 |
Sakurai, T | 1 |
Nagai, H | 1 |
Staiger, JF | 1 |
Redecker, C | 1 |
Zilles, K | 1 |
Fritschy, JM | 1 |
Möhler, H | 1 |
Shimizu-Sasamata, M | 1 |
Bosque-Hamilton, P | 1 |
Huang, PL | 1 |
Moskowitz, MA | 1 |
Lo, EH | 1 |
Moretti, R | 1 |
Torre, P | 1 |
Antonello, RM | 1 |
Nasuelli, D | 1 |
Cazzato, G | 1 |
Togashi, H | 1 |
Nakamura, K | 1 |
Matsumoto, M | 1 |
Ueno, K | 1 |
Ohashi, S | 1 |
Saito, H | 1 |
Yoshioka, M | 1 |
Kothbauer, P | 2 |
Yoshino, Y | 1 |
Koike, H | 1 |
Tomita, T | 1 |
Amroian, EA | 1 |
Vartazarian, ND | 1 |
Parsamian, LK | 1 |
Balian, LS | 1 |
Bruhn, H | 1 |
Frahm, J | 1 |
Gyngell, ML | 1 |
Merboldt, KD | 1 |
Hänicke, W | 1 |
Sauter, R | 1 |
Bando, K | 1 |
Hatanaka, Y | 1 |
Ohbayashi, S | 1 |
Irino, O | 1 |
Venables, GS | 1 |
Miller, SA | 1 |
Gibson, G | 1 |
Hardy, JA | 1 |
Strong, AJ | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Transcranial Direct Current Stimulation on Inhibitory Control in Addictions: a Triple-blinded, Sham-controlled Clinical Trial.[NCT05350033] | 200 participants (Anticipated) | Interventional | 2021-04-05 | Enrolling by invitation | |||
The Øresund Copenhagen-Malmø Acute Stroke Cooling Trial[NCT01500421] | Phase 2 | 31 participants (Actual) | Interventional | 2008-10-31 | Completed | ||
A Multicentre, Double-blind, Randomized, Phase IV Clinical Trial Comparing the Safety, Tolerability and Efficacy of Levetiracetam Versus Lamotrigine and Carbamazepine in the Oral Antiepileptic Therapy of Newly Diagnosed Elderly Patients With Focal Epileps[NCT00438451] | Phase 4 | 361 participants (Actual) | Interventional | 2007-01-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
(NCT00438451)
Timeframe: 58 weeks
Intervention | proportion of participants (Mean) |
---|---|
Levetiracetam | 0.61 |
Carbamazepine | 0.46 |
Lamotrigine | 0.56 |
Percentage of patients experiencing no seizures until week 58 (Visit 6) and did not discontinue the study until week 58. (NCT00438451)
Timeframe: week 58
Intervention | percentage of participants (Number) |
---|---|
Levetiracetam | 43 |
Carbamazepine | 33 |
Lamotrigine | 38 |
Percentage of patients experiencing no seizures until week 30 (Visit 4) and did not discontinue the study until week 30. (NCT00438451)
Timeframe: Week 30
Intervention | percentage of participants (Number) |
---|---|
Levetiracetam | 48 |
Carbamazepine | 39 |
Lamotrigine | 49 |
(NCT00438451)
Timeframe: 52 weeks
Intervention | proportion of seizure-free days (Number) |
---|---|
Levetiracetam | 0.99 |
Carbamazepine | 0.99 |
Lamotrigine | 0.99 |
EPITrack-Score shows the performance of attention and executive functions. Higher values indicate a better performance. The results of EPITrack Score ranges between 7 and 45. (NCT00438451)
Timeframe: week 58
Intervention | units on a scale (Mean) |
---|---|
Levetiracetam | 26.0 |
Carbamazepine | 26.0 |
Lamotrigine | 25.4 |
"Seizure frequency was assessed by investigators in the CRF at the Visits V3, V4, V5 and V6.~The absolute seizure frequency during the maintenance phase was defined as the sum of those entries." (NCT00438451)
Timeframe: over 52 weeks
Intervention | number of seizures (Number) |
---|---|
Levetiracetam | 168 |
Carbamazepine | 131 |
Lamotrigine | 130 |
(NCT00438451)
Timeframe: over the whole duration of 58 weeks
Intervention | days (Median) |
---|---|
Levetiracetam | NA |
Carbamazepine | NA |
Lamotrigine | NA |
number of days between randomization and premature discontinuation of the study (NCT00438451)
Timeframe: 58 weeks
Intervention | days (Median) |
---|---|
Levetiracetam | NA |
Carbamazepine | 265 |
Lamotrigine | NA |
"The PNS is a 15-item scale. Each item can be scored from 1 to 9. There are a total score (includes all items, range:15 to 135) and two subscores: The cognitive toxicity subscore (10 items: Energy Level, Memory, Interest, Concentration, Forgetfulness, Sleepliness, Moodiness, Alertness, Attention Span, Motivation, range:10 to 90) and the somatomoto subscore (5 items: Vision, Walking, Coordination, Tremor, Speech, range:5-45). The score is calculated by taking the mean of all non-missing values times the number of items.~Lower values indicate better quality of life." (NCT00438451)
Timeframe: at week 58
Intervention | units on a scale (Mean) | ||
---|---|---|---|
Cognitive toxicity subscore | Somatomotor subscore | Total Score | |
Carbamazepine | 27.3 | 11.4 | 38.7 |
Lamotrigine | 23.7 | 10.8 | 34.5 |
Levetiracetam | 22.2 | 10.5 | 32.7 |
The QOLIE-31 is a 31 item score that measures the quality of life in epilepsy (each item with a range of 0 to 100). There are 7 sub-scores seizure worry (items 11,21,22,23,25), overall quality of life (items 1,14), emotional well-being (items 3,4,5,7,9), energy/fatigue (items 2,6,8,10), cognitive functioning (items 12,15,16,17,18,26), medication effects (items 24,29,30) and social functioning (13,19,20,27,28). These scores were combined to a total score by Total score = seizure worry*0.08 + overall quality of life*0.14 + emotional well-being*0.15 + energy/fatigue*0.12 + cognitive functioning*0.27 + medication effects*0.03 + social functioning*0.21 For all scores, higher values indicate better quality of life. Each score has a possible range from 0 to 100. (NCT00438451)
Timeframe: 58 weeks, final visit
Intervention | units on a scale (Mean) | ||||||||
---|---|---|---|---|---|---|---|---|---|
Seizure worry | Overall quality of life | Emotional well-being | Energy/fatigue | Cognitive functioning | Medication effects | Social functioning | Total Score | Health Scale | |
Carbamazepine | 75.4 | 65.0 | 69.8 | 54.5 | 68.9 | 70.6 | 76.3 | 68.9 | 65.7 |
Lamotrigine | 75.0 | 67.1 | 67.4 | 59.8 | 68.0 | 72.6 | 76.7 | 69.1 | 67.5 |
Levetiracetam | 85.1 | 67.2 | 72.0 | 60.8 | 75.1 | 77.6 | 81.1 | 73.9 | 69.5 |
"Evaluation of current testing at V6:~≥29 score points: Inconspicuous; 26 to 28 score points: Borderline;~≤25 score points: Impaired" (NCT00438451)
Timeframe: 58 weeks
Intervention | participants (Number) | ||
---|---|---|---|
Without pathological findings | Borderline | Impaired | |
Carbamazepine | 34 | 17 | 33 |
Lamotrigine | 31 | 15 | 39 |
Levetiracetam | 38 | 10 | 36 |
"Evaluation of Changes~Changes in the EpiTrack® Score were categorized as follows:~≥5 score points: Improved;~-3 to 4 score points: Unchanged;~≤-4 score points: Worsened" (NCT00438451)
Timeframe: week 58
Intervention | participants (Number) | ||
---|---|---|---|
Improved | Unchanged | Worsened | |
Carbamazepine | 16 | 56 | 8 |
Lamotrigine | 15 | 53 | 13 |
Levetiracetam | 15 | 61 | 6 |
4 reviews available for gamma-aminobutyric acid and Anterior Choroidal Artery Infarction
Article | Year |
---|---|
[Future neuroprotective strategies in the post-thrombolysis era--neurovascular unit protection and vascular endothelial protection].
Topics: Amines; Animals; Antipyrine; Cerebral Infarction; Cyclohexanecarboxylic Acids; Edaravone; Endotheliu | 2011 |
Brain excitability in stroke: the yin and yang of stroke progression.
Topics: Brain; Cerebral Infarction; Disease Progression; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Lea | 2012 |
Progressive lacunar stroke: review of mechanisms, prognostic features, and putative treatments.
Topics: Anticoagulants; Blood Pressure; Brain Edema; Cerebral Infarction; Disease Progression; Encephalitis; | 2012 |
Persistent hiccups during rehabilitation hospitalization: three case reports and review of the literature.
Topics: Aged; Amines; Anti-Anxiety Agents; Anticonvulsants; Cerebral Infarction; Chlorpromazine; Chronic Dis | 2007 |
2 trials available for gamma-aminobutyric acid and Anterior Choroidal Artery Infarction
Article | Year |
---|---|
New onset geriatric epilepsy: a randomized study of gabapentin, lamotrigine, and carbamazepine.
Topics: Aged; Aging; Amines; Anticonvulsants; Carbamazepine; Cerebral Infarction; Cyclohexanecarboxylic Acid | 2005 |
Treatment of chronic: new perspectives.
Topics: Acetates; Aged; Amines; Cerebral Infarction; Chronic Disease; Cyclohexanecarboxylic Acids; Excitator | 1999 |
33 other studies available for gamma-aminobutyric acid and Anterior Choroidal Artery Infarction
Article | Year |
---|---|
Targeting the interaction of GABA
Topics: Animals; Brain; Brain Ischemia; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cerebral Infarct | 2023 |
Insights into the role of pERK1/2 signaling in post-cerebral ischemia reperfusion sexual dysfunction in rats.
Topics: Animals; Brain Ischemia; Brain-Derived Neurotrophic Factor; Cerebral Infarction; gamma-Aminobutyric | 2022 |
Experimental Substantiation of the Use of Phenibut Combinations with Salicylic, Nicotinic, and Glutamic Acids in Cerebral Ischemia.
Topics: Animals; Brain Ischemia; Cerebral Infarction; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Male; | 2023 |
[Effects of Governor Vessel electroacupuncture on chloridion homeostasis in the cortex of rats with limb spasm after cerebral ischemia-reperfusion].
Topics: Animals; Baclofen; Cerebral Cortex; Cerebral Infarction; Electroacupuncture; gamma-Aminobutyric Acid | 2023 |
[Ghrelin protects against hippocampal injury after global cerebral ischemia/reperfusion and regulate glutamic acid/γ-aminobutyric acid sensitive neuron discharge]
Topics: Animals; Brain; Brain Ischemia; Cerebral Infarction; gamma-Aminobutyric Acid; Ghrelin; Glutamic Acid | 2016 |
Neurological picture. Trigeminal neuralgia after pontine infarction affecting the ipsilateral trigeminal nerve.
Topics: Amines; Analgesics, Non-Narcotic; Carbamazepine; Cerebral Infarction; Cyclohexanecarboxylic Acids; G | 2013 |
Gabapentin therapy for ocular opsoclonus-myoclonus restores eye movement communication in a patient with a locked-in syndrome.
Topics: Adult; Amines; Anticonvulsants; Cerebral Infarction; Cyclohexanecarboxylic Acids; Female; Gabapentin | 2010 |
Reducing excessive GABA-mediated tonic inhibition promotes functional recovery after stroke.
Topics: Animals; Benzodiazepines; Cerebral Infarction; Disease Models, Animal; Drug Inverse Agonism; GABA An | 2010 |
Stroke: recovery inhibitors under attack.
Topics: Animals; Cerebral Infarction; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Mice | 2010 |
[Effect of sailuotong capsule on Glu and GABA levels as well as NMDA receptor subtypes expression in recovery period of rat multiple cerebral infarction].
Topics: Animals; Capsules; Cerebral Cortex; Cerebral Infarction; Drug Combinations; Drugs, Chinese Herbal; g | 2012 |
Successful use of zonisamide for central poststroke pain.
Topics: Anticonvulsants; Calcium Channel Blockers; Calcium Channels, T-Type; Cerebral Infarction; Diabetes C | 2004 |
Prolonged moderate hypothermia in massive hemispheric infarction: clinical experience.
Topics: Adult; Cerebral Infarction; Female; gamma-Aminobutyric Acid; Humans; Hypotension; Hypothermia, Induc | 2005 |
Enhancement of neuroprotection of mulberry leaves (Morus alba L.) prepared by the anaerobic treatment against ischemic damage.
Topics: Anaerobiosis; Animals; Brain Ischemia; Cell Hypoxia; Cell Survival; Cerebral Infarction; gamma-Amino | 2006 |
Improved expression of gamma-aminobutyric acid receptor in mice with cerebral infarct and transplanted bone marrow stromal cells: an autoradiographic and histologic analysis.
Topics: Animals; Brain; Cerebral Infarction; gamma-Aminobutyric Acid; Hematopoietic Stem Cell Transplantatio | 2006 |
Expression of GABA A receptor alpha1 subunit mRNA and protein in rat neocortex following photothrombotic infarction.
Topics: Animals; Cerebral Infarction; Disease Models, Animal; Down-Regulation; Epilepsy; Functional Laterali | 2008 |
[Central neurotransmitters in cerebral ischemia and stroke].
Topics: Animals; Blood-Brain Barrier; Brain Edema; Brain Ischemia; Cerebral Infarction; Cerebrovascular Diso | 1983 |
[Problems of the treatment of cerebral infarction].
Topics: Aged; Animals; Aspirin; Brain; Cerebral Infarction; Cerebrovascular Circulation; Dextrans; Female; g | 1983 |
Gamma-aminobutyric acid (GABA) in cerebrospinal fluid.
Topics: Adult; Behcet Syndrome; Cerebellar Diseases; Cerebral Infarction; Dementia; Female; gamma-Aminobutyr | 1983 |
Plasma and cerebrospinal fluid gamma-aminobutyric acid in neurological disorders.
Topics: Brain Neoplasms; Cerebral Infarction; Epilepsy; Female; gamma-Aminobutyric Acid; Humans; Male; Menin | 1982 |
Cellular correlates of neuronal hyperexcitability in the vicinity of photochemically induced cortical infarcts in rats in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebral Cortex; Cerebral Infarction; Electrophysiology; gamma | 1995 |
Combination therapy protects ischemic brain in rats. A glutamate antagonist plus a gamma-aminobutyric acid agonist.
Topics: Animals; Brain; Brain Ischemia; Cerebral Infarction; Dizocilpine Maleate; Drug Combinations; Excitat | 1994 |
Striatal grafts in infarct striatopallidum increase GABA release, reorganize GABAA receptor and improve water-maze learning in the rat.
Topics: Animals; Autoradiography; Brain Ischemia; Brain Tissue Transplantation; Cell Transplantation; Cerebr | 1994 |
Striatal grafts in the ischemic striatum improve pallidal GABA release and passive avoidance.
Topics: Animals; Avoidance Learning; Behavior, Animal; Brain Ischemia; Cerebral Infarction; Corpus Striatum; | 1993 |
Immunohistochemical evidence for dysregulation of the GABAergic system ipsilateral to photochemically induced cortical infarcts in rats.
Topics: Animals; Brain Ischemia; Cerebral Infarction; Dominance, Cerebral; gamma-Aminobutyric Acid; Gene Exp | 1998 |
Attenuated neurotransmitter release and spreading depression-like depolarizations after focal ischemia in mutant mice with disrupted type I nitric oxide synthase gene.
Topics: Alanine; Animals; Brain; Brain Ischemia; Cerebral Infarction; Cerebrovascular Circulation; Cortical | 1998 |
Aniracetam enhances glutamatergic transmission in the prefrontal cortex of stroke-prone spontaneously hypertensive rats.
Topics: Amino Acids; Amygdala; Animals; Cerebral Infarction; Extracellular Space; gamma-Aminobutyric Acid; G | 2002 |
Changes of some putative neurotransmitters in human cerebral infarction.
Topics: Aged; Autopsy; Brain; Cerebral Infarction; Dopamine; Female; gamma-Aminobutyric Acid; Humans; Hydrox | 1978 |
[The significance of biogenic amines in cerebral infarction (author's transl)].
Topics: Aged; Biogenic Amines; Brain; Cerebral Infarction; Dopamine; gamma-Aminobutyric Acid; Humans; Hydrox | 1979 |
[Free amino acids of blood plasma and erythrocytes from patients with cerebral infarction (author's transl)].
Topics: Adult; Aged; Amino Acids; Cerebral Infarction; Erythrocytes; Female; gamma-Aminobutyric Acid; Humans | 1978 |
[Effects of GABA and piracetam on the development of experimental cerebral infarction in rats and platelet aggregation in patients with cerebrovascular disorders].
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Brain; Cerebral Infarction; Cerebrovascular Disorders; | 1990 |
Cerebral metabolism in man after acute stroke: new observations using localized proton NMR spectroscopy.
Topics: Adult; Aspartic Acid; Brain; Brain Ischemia; Cerebral Infarction; Cerebrovascular Disorders; gamma-A | 1989 |
[A quantitative measurement of the cerebral infarct focus induced by arachidonate infusion and the relationship between measured values and stroke signs].
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Brain; Cerebral Infarction; Cerebrovascular Disorders; | 1988 |
The effects of hyperglycaemia on changes during reperfusion following focal cerebral ischaemia in the cat.
Topics: Animals; Blood Glucose; Brain Ischemia; Cats; Cerebral Cortex; Cerebral Infarction; Cerebrovascular | 1985 |