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gamma-aminobutyric acid and Anterior Choroidal Artery Infarction

gamma-aminobutyric acid has been researched along with Anterior Choroidal Artery Infarction in 39 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Research Excerpts

ExcerptRelevanceReference
"To determine the relative tolerability and efficacy of two newer antiepileptic drugs, lamotrigine (LTG) and gabapentin (GBP), as compared to carbamazepine (CBZ) in older patients with epilepsy."9.11New onset geriatric epilepsy: a randomized study of gabapentin, lamotrigine, and carbamazepine. ( Boardman, KD; Carter, GS; Collins, JF; Felicetta, J; Frederick, T; Marks, W; Pryor, F; Ramsay, RE; Rowan, AJ; Spitz, M; Tomyanovich, ML; Towne, A; Uthman, BM, 2005)
"Compositions of phenibut with salicylic, nicotinic, and glutamic acids in subtotal and transient cerebral ischemia were found to have the most pronounced cerebroprotective effect in doses of 30, 50 and 50 mg/kg, respectively."8.31Experimental Substantiation of the Use of Phenibut Combinations with Salicylic, Nicotinic, and Glutamic Acids in Cerebral Ischemia. ( Monov, D; Pashanova, O, 2023)
"We present 2 patients with severe and intractable central poststroke pain (CPSP) after right posterolateral thalamic infarcts who were successfully treated with zonisamide."7.72Successful use of zonisamide for central poststroke pain. ( Hashimoto, K; Takahashi, Y; Tsuji, S, 2004)
"The effects of aniracetam, a cognition enhancer, on extracellular levels of glutamate (Glu), gamma-aminobutyric acid (GABA) and nitric oxide metabolites (NOx) were examined in the prefrontal cortex (PFC) and the basolateral amygdala (AMG) in stroke-prone spontaneously hypertensive rats (SHRSP) using in vivo microdialysis."7.71Aniracetam enhances glutamatergic transmission in the prefrontal cortex of stroke-prone spontaneously hypertensive rats. ( Matsumoto, M; Nakamura, K; Ohashi, S; Saito, H; Togashi, H; Ueno, K; Yoshioka, M, 2002)
"GABA and Piracetam caused the improvement of the morphological state of cerebral infarction, due to intracarotid infusion of Arachidonic acid."7.68[Effects of GABA and piracetam on the development of experimental cerebral infarction in rats and platelet aggregation in patients with cerebrovascular disorders]. ( Amroian, EA; Balian, LS; Parsamian, LK; Vartazarian, ND, 1990)
"The most common etiology was cerebral infarction."6.71New onset geriatric epilepsy: a randomized study of gabapentin, lamotrigine, and carbamazepine. ( Boardman, KD; Carter, GS; Collins, JF; Felicetta, J; Frederick, T; Marks, W; Pryor, F; Ramsay, RE; Rowan, AJ; Spitz, M; Tomyanovich, ML; Towne, A; Uthman, BM, 2005)
"To determine the relative tolerability and efficacy of two newer antiepileptic drugs, lamotrigine (LTG) and gabapentin (GBP), as compared to carbamazepine (CBZ) in older patients with epilepsy."5.11New onset geriatric epilepsy: a randomized study of gabapentin, lamotrigine, and carbamazepine. ( Boardman, KD; Carter, GS; Collins, JF; Felicetta, J; Frederick, T; Marks, W; Pryor, F; Ramsay, RE; Rowan, AJ; Spitz, M; Tomyanovich, ML; Towne, A; Uthman, BM, 2005)
"Compositions of phenibut with salicylic, nicotinic, and glutamic acids in subtotal and transient cerebral ischemia were found to have the most pronounced cerebroprotective effect in doses of 30, 50 and 50 mg/kg, respectively."4.31Experimental Substantiation of the Use of Phenibut Combinations with Salicylic, Nicotinic, and Glutamic Acids in Cerebral Ischemia. ( Monov, D; Pashanova, O, 2023)
" In the present study, therefore, we aimed to elucidate whether BMSC express the neuron-specific gamma-aminobutyric acid (GABA) receptor when transplanted into brain that has been subjected to cerebral infarction."3.73Improved expression of gamma-aminobutyric acid receptor in mice with cerebral infarct and transplanted bone marrow stromal cells: an autoradiographic and histologic analysis. ( Hida, K; Iwasaki, Y; Kuroda, S; Ohnishi, T; Shichinohe, H; Tamagami, H; Yano, S, 2006)
"We present 2 patients with severe and intractable central poststroke pain (CPSP) after right posterolateral thalamic infarcts who were successfully treated with zonisamide."3.72Successful use of zonisamide for central poststroke pain. ( Hashimoto, K; Takahashi, Y; Tsuji, S, 2004)
"The effects of aniracetam, a cognition enhancer, on extracellular levels of glutamate (Glu), gamma-aminobutyric acid (GABA) and nitric oxide metabolites (NOx) were examined in the prefrontal cortex (PFC) and the basolateral amygdala (AMG) in stroke-prone spontaneously hypertensive rats (SHRSP) using in vivo microdialysis."3.71Aniracetam enhances glutamatergic transmission in the prefrontal cortex of stroke-prone spontaneously hypertensive rats. ( Matsumoto, M; Nakamura, K; Ohashi, S; Saito, H; Togashi, H; Ueno, K; Yoshioka, M, 2002)
"GABA and Piracetam caused the improvement of the morphological state of cerebral infarction, due to intracarotid infusion of Arachidonic acid."3.68[Effects of GABA and piracetam on the development of experimental cerebral infarction in rats and platelet aggregation in patients with cerebrovascular disorders]. ( Amroian, EA; Balian, LS; Parsamian, LK; Vartazarian, ND, 1990)
"Dopamine (DA), serotonin (5-HT), tryptophan (TRP), 5-hydroxyindole acetic acid (5-HIAA), and GABA were assayed spectrofluorometrically in various regions of 16 human post-mortem brains with acute and old cerebral infarction."3.66Changes of some putative neurotransmitters in human cerebral infarction. ( Jellinger, K; Kothbauer, P; Riederer, P, 1978)
"The most common etiology was cerebral infarction."2.71New onset geriatric epilepsy: a randomized study of gabapentin, lamotrigine, and carbamazepine. ( Boardman, KD; Carter, GS; Collins, JF; Felicetta, J; Frederick, T; Marks, W; Pryor, F; Ramsay, RE; Rowan, AJ; Spitz, M; Tomyanovich, ML; Towne, A; Uthman, BM, 2005)
"However 20-30% of patients with lacunar stroke worsen neurologically in hours or days after onset, reaching eventually an unexpectedly severe disability status."2.48Progressive lacunar stroke: review of mechanisms, prognostic features, and putative treatments. ( Del Bene, A; Inzitari, D; Lamassa, M; Palumbo, V; Piccardi, B; Saia, V, 2012)
"Persistent hiccups have been reported to occur occasionally during rehabilitation hospitalizations."2.44Persistent hiccups during rehabilitation hospitalization: three case reports and review of the literature. ( Browne, BA; Schuchmann, JA, 2007)
"Cerebral ischemia is the leading cause for long-term disability and mortality in adults due to massive neuronal death."1.91Targeting the interaction of GABA ( Balakrishnan, K; Benke, D; Bhat, MA; Ganley, RP; Hleihil, M; Klohs, J; Vaas, M; Zeilhofer, HU, 2023)
"TTC staining was used to detect cerebral infarction volume, and the brain water content of rats in each group was determined by wet and dry weight method."1.91[Effects of Governor Vessel electroacupuncture on chloridion homeostasis in the cortex of rats with limb spasm after cerebral ischemia-reperfusion]. ( Guo, J; Li, JW; Li, RQ; Mei, JJ; Wang, YY; Zhang, JY; Zhang, LH, 2023)
"This study utilized a cerebral ischemia reperfusion (IR) model to produce a stressful brain condition that highlights the possible involvement of a hippocampal GC/pERK1/2/BDNF pathway in the resulting sexual consequences of this ailment."1.72Insights into the role of pERK1/2 signaling in post-cerebral ischemia reperfusion sexual dysfunction in rats. ( El-Sahar, AE; Khattab, MA; Mohammed, RA; Saad, MA; Sayed, RH, 2022)
"Stroke is a leading cause of disability, but no pharmacological therapy is currently available for promoting recovery."1.36Reducing excessive GABA-mediated tonic inhibition promotes functional recovery after stroke. ( Carmichael, ST; Clarkson, AN; Huang, BS; Macisaac, SE; Mody, I, 2010)
"Malignant cerebral infarction (MaCI) treated with mechanical ventilation, mannitol, or barbiturates has a mortality of about 80% and survivors show severe disability."1.33Prolonged moderate hypothermia in massive hemispheric infarction: clinical experience. ( Escuret, E; Heroum, C; Milhaud, D; Thouvenot, E, 2005)
"In 49 patients with various neurological disorders plasma and CSF gamma-aminobutyric acid (GABA) concentrations were determined by radioreceptor assay."1.26Plasma and cerebrospinal fluid gamma-aminobutyric acid in neurological disorders. ( Löscher, W; Schmidt, D, 1982)

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199010 (25.64)18.7374
1990's8 (20.51)18.2507
2000's8 (20.51)29.6817
2010's9 (23.08)24.3611
2020's4 (10.26)2.80

Authors

AuthorsStudies
Balakrishnan, K1
Hleihil, M1
Bhat, MA1
Ganley, RP1
Vaas, M1
Klohs, J1
Zeilhofer, HU1
Benke, D1
Mohammed, RA1
Sayed, RH1
El-Sahar, AE1
Khattab, MA1
Saad, MA1
Monov, D1
Pashanova, O1
Wang, YY1
Li, RQ1
Li, JW1
Mei, JJ1
Zhang, LH1
Zhang, JY1
Guo, J1
Zhang, M1
Sun, X1
Guo, F1
Gong, Y1
Xu, L2
Kim, JB1
Yu, S1
Pistoia, F1
Sarà, M1
Clarkson, AN1
Huang, BS1
Macisaac, SE1
Mody, I1
Carmichael, ST2
Staley, K1
Kamiya, T1
Abe, K1
Del Bene, A1
Palumbo, V1
Lamassa, M1
Saia, V1
Piccardi, B1
Inzitari, D1
Song, WT1
Lin, CR1
Ren, JX1
Liu, JX1
Yao, MJ1
Wang, GR1
Takahashi, Y1
Hashimoto, K1
Tsuji, S1
Milhaud, D1
Thouvenot, E1
Heroum, C1
Escuret, E1
Rowan, AJ1
Ramsay, RE1
Collins, JF1
Pryor, F1
Boardman, KD1
Uthman, BM1
Spitz, M1
Frederick, T1
Towne, A1
Carter, GS1
Marks, W1
Felicetta, J1
Tomyanovich, ML1
Kang, TH1
Oh, HR1
Jung, SM1
Ryu, JH1
Park, MW1
Park, YK1
Kim, SY1
Shichinohe, H1
Kuroda, S1
Yano, S1
Ohnishi, T1
Tamagami, H1
Hida, K1
Iwasaki, Y1
Schuchmann, JA1
Browne, BA1
Kharlamov, EA1
Downey, KL1
Jukkola, PI1
Grayson, DR1
Kelly, KM1
Jellinger, K3
Riederer, P3
Kameyama, M1
Kuroda, H1
Schmidt, D1
Löscher, W1
Neumann-Haefelin, T2
Hagemann, G1
Witte, OW2
Lyden, PD1
Lonzo, L1
Aihara, N2
Mizukawa, K1
Koide, K2
Mabe, H1
Nishino, H2
Kumazaki, M1
Sakurai, T1
Nagai, H1
Staiger, JF1
Redecker, C1
Zilles, K1
Fritschy, JM1
Möhler, H1
Shimizu-Sasamata, M1
Bosque-Hamilton, P1
Huang, PL1
Moskowitz, MA1
Lo, EH1
Moretti, R1
Torre, P1
Antonello, RM1
Nasuelli, D1
Cazzato, G1
Togashi, H1
Nakamura, K1
Matsumoto, M1
Ueno, K1
Ohashi, S1
Saito, H1
Yoshioka, M1
Kothbauer, P2
Yoshino, Y1
Koike, H1
Tomita, T1
Amroian, EA1
Vartazarian, ND1
Parsamian, LK1
Balian, LS1
Bruhn, H1
Frahm, J1
Gyngell, ML1
Merboldt, KD1
Hänicke, W1
Sauter, R1
Bando, K1
Hatanaka, Y1
Ohbayashi, S1
Irino, O1
Venables, GS1
Miller, SA1
Gibson, G1
Hardy, JA1
Strong, AJ1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Transcranial Direct Current Stimulation on Inhibitory Control in Addictions: a Triple-blinded, Sham-controlled Clinical Trial.[NCT05350033]200 participants (Anticipated)Interventional2021-04-05Enrolling by invitation
The Øresund Copenhagen-Malmø Acute Stroke Cooling Trial[NCT01500421]Phase 231 participants (Actual)Interventional2008-10-31Completed
A Multicentre, Double-blind, Randomized, Phase IV Clinical Trial Comparing the Safety, Tolerability and Efficacy of Levetiracetam Versus Lamotrigine and Carbamazepine in the Oral Antiepileptic Therapy of Newly Diagnosed Elderly Patients With Focal Epileps[NCT00438451]Phase 4361 participants (Actual)Interventional2007-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

58-week Retention Rate Measured by the Number of Drop Outs Due to Adverse Events or Seizures From Day 1 of Treatment

(NCT00438451)
Timeframe: 58 weeks

Interventionproportion of participants (Mean)
Levetiracetam0.61
Carbamazepine0.46
Lamotrigine0.56

Percentage of Patients Remaining Seizure Free at Week 58 (Visit 6)

Percentage of patients experiencing no seizures until week 58 (Visit 6) and did not discontinue the study until week 58. (NCT00438451)
Timeframe: week 58

Interventionpercentage of participants (Number)
Levetiracetam43
Carbamazepine33
Lamotrigine38

Percentage of Patients Remaining Seizure-free at Week 30 (Visit 4)

Percentage of patients experiencing no seizures until week 30 (Visit 4) and did not discontinue the study until week 30. (NCT00438451)
Timeframe: Week 30

Interventionpercentage of participants (Number)
Levetiracetam48
Carbamazepine39
Lamotrigine49

Proportion of Seizure-free Days During the Maintenance Phase for Subjects Who Enter the Maintenance Phase

(NCT00438451)
Timeframe: 52 weeks

Interventionproportion of seizure-free days (Number)
Levetiracetam0.99
Carbamazepine0.99
Lamotrigine0.99

Results of Cognitive Testing (EpiTrack© by UCB) - Score at V6

EPITrack-Score shows the performance of attention and executive functions. Higher values indicate a better performance. The results of EPITrack Score ranges between 7 and 45. (NCT00438451)
Timeframe: week 58

Interventionunits on a scale (Mean)
Levetiracetam26.0
Carbamazepine26.0
Lamotrigine25.4

The Absolute Seizure Frequency During the Maintenance Phase (Weeks 7 - 58)

"Seizure frequency was assessed by investigators in the CRF at the Visits V3, V4, V5 and V6.~The absolute seizure frequency during the maintenance phase was defined as the sum of those entries." (NCT00438451)
Timeframe: over 52 weeks

Interventionnumber of seizures (Number)
Levetiracetam168
Carbamazepine131
Lamotrigine130

The Time (in Days) to First Break-through Seizure (From Day 1 of Treatment)

(NCT00438451)
Timeframe: over the whole duration of 58 weeks

Interventiondays (Median)
LevetiracetamNA
CarbamazepineNA
LamotrigineNA

Time to Drop Out

number of days between randomization and premature discontinuation of the study (NCT00438451)
Timeframe: 58 weeks

Interventiondays (Median)
LevetiracetamNA
Carbamazepine265
LamotrigineNA

Portland Neurotoxicity Scale (PNS) at V6

"The PNS is a 15-item scale. Each item can be scored from 1 to 9. There are a total score (includes all items, range:15 to 135) and two subscores: The cognitive toxicity subscore (10 items: Energy Level, Memory, Interest, Concentration, Forgetfulness, Sleepliness, Moodiness, Alertness, Attention Span, Motivation, range:10 to 90) and the somatomoto subscore (5 items: Vision, Walking, Coordination, Tremor, Speech, range:5-45). The score is calculated by taking the mean of all non-missing values times the number of items.~Lower values indicate better quality of life." (NCT00438451)
Timeframe: at week 58

,,
Interventionunits on a scale (Mean)
Cognitive toxicity subscoreSomatomotor subscoreTotal Score
Carbamazepine27.311.438.7
Lamotrigine23.710.834.5
Levetiracetam22.210.532.7

QOLIE-31 (Quality Of Life In Epilepsy) Results at V6

The QOLIE-31 is a 31 item score that measures the quality of life in epilepsy (each item with a range of 0 to 100). There are 7 sub-scores seizure worry (items 11,21,22,23,25), overall quality of life (items 1,14), emotional well-being (items 3,4,5,7,9), energy/fatigue (items 2,6,8,10), cognitive functioning (items 12,15,16,17,18,26), medication effects (items 24,29,30) and social functioning (13,19,20,27,28). These scores were combined to a total score by Total score = seizure worry*0.08 + overall quality of life*0.14 + emotional well-being*0.15 + energy/fatigue*0.12 + cognitive functioning*0.27 + medication effects*0.03 + social functioning*0.21 For all scores, higher values indicate better quality of life. Each score has a possible range from 0 to 100. (NCT00438451)
Timeframe: 58 weeks, final visit

,,
Interventionunits on a scale (Mean)
Seizure worryOverall quality of lifeEmotional well-beingEnergy/fatigueCognitive functioningMedication effectsSocial functioningTotal ScoreHealth Scale
Carbamazepine75.465.069.854.568.970.676.368.965.7
Lamotrigine75.067.167.459.868.072.676.769.167.5
Levetiracetam85.167.272.060.875.177.681.173.969.5

Results of Cognitive Testing (EpiTrack© by UCB) - Categories at V6

"Evaluation of current testing at V6:~≥29 score points: Inconspicuous; 26 to 28 score points: Borderline;~≤25 score points: Impaired" (NCT00438451)
Timeframe: 58 weeks

,,
Interventionparticipants (Number)
Without pathological findingsBorderlineImpaired
Carbamazepine341733
Lamotrigine311539
Levetiracetam381036

Results of Cognitive Testing (EpiTrack© by UCB) - Changes to Baseline (V0) at Week 58 (V6)

"Evaluation of Changes~Changes in the EpiTrack® Score were categorized as follows:~≥5 score points: Improved;~-3 to 4 score points: Unchanged;~≤-4 score points: Worsened" (NCT00438451)
Timeframe: week 58

,,
Interventionparticipants (Number)
ImprovedUnchangedWorsened
Carbamazepine16568
Lamotrigine155313
Levetiracetam15616

Reviews

4 reviews available for gamma-aminobutyric acid and Anterior Choroidal Artery Infarction

ArticleYear
[Future neuroprotective strategies in the post-thrombolysis era--neurovascular unit protection and vascular endothelial protection].
    Rinsho shinkeigaku = Clinical neurology, 2011, Volume: 51, Issue:5

    Topics: Amines; Animals; Antipyrine; Cerebral Infarction; Cyclohexanecarboxylic Acids; Edaravone; Endotheliu

2011
Brain excitability in stroke: the yin and yang of stroke progression.
    Archives of neurology, 2012, Volume: 69, Issue:2

    Topics: Brain; Cerebral Infarction; Disease Progression; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Lea

2012
Progressive lacunar stroke: review of mechanisms, prognostic features, and putative treatments.
    International journal of stroke : official journal of the International Stroke Society, 2012, Volume: 7, Issue:4

    Topics: Anticoagulants; Blood Pressure; Brain Edema; Cerebral Infarction; Disease Progression; Encephalitis;

2012
Persistent hiccups during rehabilitation hospitalization: three case reports and review of the literature.
    American journal of physical medicine & rehabilitation, 2007, Volume: 86, Issue:12

    Topics: Aged; Amines; Anti-Anxiety Agents; Anticonvulsants; Cerebral Infarction; Chlorpromazine; Chronic Dis

2007

Trials

2 trials available for gamma-aminobutyric acid and Anterior Choroidal Artery Infarction

ArticleYear
New onset geriatric epilepsy: a randomized study of gabapentin, lamotrigine, and carbamazepine.
    Neurology, 2005, Jun-14, Volume: 64, Issue:11

    Topics: Aged; Aging; Amines; Anticonvulsants; Carbamazepine; Cerebral Infarction; Cyclohexanecarboxylic Acid

2005
Treatment of chronic: new perspectives.
    European journal of neurology, 1999, Volume: 6, Issue:5

    Topics: Acetates; Aged; Amines; Cerebral Infarction; Chronic Disease; Cyclohexanecarboxylic Acids; Excitator

1999

Other Studies

33 other studies available for gamma-aminobutyric acid and Anterior Choroidal Artery Infarction

ArticleYear
Targeting the interaction of GABA
    Brain pathology (Zurich, Switzerland), 2023, Volume: 33, Issue:1

    Topics: Animals; Brain; Brain Ischemia; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cerebral Infarct

2023
Insights into the role of pERK1/2 signaling in post-cerebral ischemia reperfusion sexual dysfunction in rats.
    European journal of pharmacology, 2022, Oct-15, Volume: 933

    Topics: Animals; Brain Ischemia; Brain-Derived Neurotrophic Factor; Cerebral Infarction; gamma-Aminobutyric

2022
Experimental Substantiation of the Use of Phenibut Combinations with Salicylic, Nicotinic, and Glutamic Acids in Cerebral Ischemia.
    Neurocritical care, 2023, Volume: 39, Issue:2

    Topics: Animals; Brain Ischemia; Cerebral Infarction; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Male;

2023
[Effects of Governor Vessel electroacupuncture on chloridion homeostasis in the cortex of rats with limb spasm after cerebral ischemia-reperfusion].
    Zhen ci yan jiu = Acupuncture research, 2023, Sep-25, Volume: 48, Issue:9

    Topics: Animals; Baclofen; Cerebral Cortex; Cerebral Infarction; Electroacupuncture; gamma-Aminobutyric Acid

2023
[Ghrelin protects against hippocampal injury after global cerebral ischemia/reperfusion and regulate glutamic acid/γ-aminobutyric acid sensitive neuron discharge]
    Zhonghua wei zhong bing ji jiu yi xue, 2016, Volume: 28, Issue:5

    Topics: Animals; Brain; Brain Ischemia; Cerebral Infarction; gamma-Aminobutyric Acid; Ghrelin; Glutamic Acid

2016
Neurological picture. Trigeminal neuralgia after pontine infarction affecting the ipsilateral trigeminal nerve.
    Journal of neurology, neurosurgery, and psychiatry, 2013, Volume: 84, Issue:8

    Topics: Amines; Analgesics, Non-Narcotic; Carbamazepine; Cerebral Infarction; Cyclohexanecarboxylic Acids; G

2013
Gabapentin therapy for ocular opsoclonus-myoclonus restores eye movement communication in a patient with a locked-in syndrome.
    Neurorehabilitation and neural repair, 2010, Volume: 24, Issue:5

    Topics: Adult; Amines; Anticonvulsants; Cerebral Infarction; Cyclohexanecarboxylic Acids; Female; Gabapentin

2010
Reducing excessive GABA-mediated tonic inhibition promotes functional recovery after stroke.
    Nature, 2010, Nov-11, Volume: 468, Issue:7321

    Topics: Animals; Benzodiazepines; Cerebral Infarction; Disease Models, Animal; Drug Inverse Agonism; GABA An

2010
Stroke: recovery inhibitors under attack.
    Nature, 2010, Nov-11, Volume: 468, Issue:7321

    Topics: Animals; Cerebral Infarction; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Mice

2010
[Effect of sailuotong capsule on Glu and GABA levels as well as NMDA receptor subtypes expression in recovery period of rat multiple cerebral infarction].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2012, Volume: 47, Issue:7

    Topics: Animals; Capsules; Cerebral Cortex; Cerebral Infarction; Drug Combinations; Drugs, Chinese Herbal; g

2012
Successful use of zonisamide for central poststroke pain.
    The journal of pain, 2004, Volume: 5, Issue:3

    Topics: Anticonvulsants; Calcium Channel Blockers; Calcium Channels, T-Type; Cerebral Infarction; Diabetes C

2004
Prolonged moderate hypothermia in massive hemispheric infarction: clinical experience.
    Journal of neurosurgical anesthesiology, 2005, Volume: 17, Issue:1

    Topics: Adult; Cerebral Infarction; Female; gamma-Aminobutyric Acid; Humans; Hypotension; Hypothermia, Induc

2005
Enhancement of neuroprotection of mulberry leaves (Morus alba L.) prepared by the anaerobic treatment against ischemic damage.
    Biological & pharmaceutical bulletin, 2006, Volume: 29, Issue:2

    Topics: Anaerobiosis; Animals; Brain Ischemia; Cell Hypoxia; Cell Survival; Cerebral Infarction; gamma-Amino

2006
Improved expression of gamma-aminobutyric acid receptor in mice with cerebral infarct and transplanted bone marrow stromal cells: an autoradiographic and histologic analysis.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2006, Volume: 47, Issue:3

    Topics: Animals; Brain; Cerebral Infarction; gamma-Aminobutyric Acid; Hematopoietic Stem Cell Transplantatio

2006
Expression of GABA A receptor alpha1 subunit mRNA and protein in rat neocortex following photothrombotic infarction.
    Brain research, 2008, May-19, Volume: 1210

    Topics: Animals; Cerebral Infarction; Disease Models, Animal; Down-Regulation; Epilepsy; Functional Laterali

2008
[Central neurotransmitters in cerebral ischemia and stroke].
    Fortschritte der Neurologie-Psychiatrie, 1983, Volume: 51, Issue:3

    Topics: Animals; Blood-Brain Barrier; Brain Edema; Brain Ischemia; Cerebral Infarction; Cerebrovascular Diso

1983
[Problems of the treatment of cerebral infarction].
    No to shinkei = Brain and nerve, 1983, Volume: 35, Issue:1

    Topics: Aged; Animals; Aspirin; Brain; Cerebral Infarction; Cerebrovascular Circulation; Dextrans; Female; g

1983
Gamma-aminobutyric acid (GABA) in cerebrospinal fluid.
    Acta medica Okayama, 1983, Volume: 37, Issue:3

    Topics: Adult; Behcet Syndrome; Cerebellar Diseases; Cerebral Infarction; Dementia; Female; gamma-Aminobutyr

1983
Plasma and cerebrospinal fluid gamma-aminobutyric acid in neurological disorders.
    Journal of neurology, neurosurgery, and psychiatry, 1982, Volume: 45, Issue:10

    Topics: Brain Neoplasms; Cerebral Infarction; Epilepsy; Female; gamma-Aminobutyric Acid; Humans; Male; Menin

1982
Cellular correlates of neuronal hyperexcitability in the vicinity of photochemically induced cortical infarcts in rats in vitro.
    Neuroscience letters, 1995, Jun-30, Volume: 193, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebral Cortex; Cerebral Infarction; Electrophysiology; gamma

1995
Combination therapy protects ischemic brain in rats. A glutamate antagonist plus a gamma-aminobutyric acid agonist.
    Stroke, 1994, Volume: 25, Issue:1

    Topics: Animals; Brain; Brain Ischemia; Cerebral Infarction; Dizocilpine Maleate; Drug Combinations; Excitat

1994
Striatal grafts in infarct striatopallidum increase GABA release, reorganize GABAA receptor and improve water-maze learning in the rat.
    Brain research bulletin, 1994, Volume: 33, Issue:5

    Topics: Animals; Autoradiography; Brain Ischemia; Brain Tissue Transplantation; Cell Transplantation; Cerebr

1994
Striatal grafts in the ischemic striatum improve pallidal GABA release and passive avoidance.
    Brain research bulletin, 1993, Volume: 32, Issue:5

    Topics: Animals; Avoidance Learning; Behavior, Animal; Brain Ischemia; Cerebral Infarction; Corpus Striatum;

1993
Immunohistochemical evidence for dysregulation of the GABAergic system ipsilateral to photochemically induced cortical infarcts in rats.
    Neuroscience, 1998, Volume: 87, Issue:4

    Topics: Animals; Brain Ischemia; Cerebral Infarction; Dominance, Cerebral; gamma-Aminobutyric Acid; Gene Exp

1998
Attenuated neurotransmitter release and spreading depression-like depolarizations after focal ischemia in mutant mice with disrupted type I nitric oxide synthase gene.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Nov-15, Volume: 18, Issue:22

    Topics: Alanine; Animals; Brain; Brain Ischemia; Cerebral Infarction; Cerebrovascular Circulation; Cortical

1998
Aniracetam enhances glutamatergic transmission in the prefrontal cortex of stroke-prone spontaneously hypertensive rats.
    Neuroscience letters, 2002, Mar-08, Volume: 320, Issue:3

    Topics: Amino Acids; Amygdala; Animals; Cerebral Infarction; Extracellular Space; gamma-Aminobutyric Acid; G

2002
Changes of some putative neurotransmitters in human cerebral infarction.
    Journal of neural transmission. Supplementum, 1978, Issue:14

    Topics: Aged; Autopsy; Brain; Cerebral Infarction; Dopamine; Female; gamma-Aminobutyric Acid; Humans; Hydrox

1978
[The significance of biogenic amines in cerebral infarction (author's transl)].
    Wiener klinische Wochenschrift, 1979, May-11, Volume: 91, Issue:10

    Topics: Aged; Biogenic Amines; Brain; Cerebral Infarction; Dopamine; gamma-Aminobutyric Acid; Humans; Hydrox

1979
[Free amino acids of blood plasma and erythrocytes from patients with cerebral infarction (author's transl)].
    No to shinkei = Brain and nerve, 1978, Volume: 30, Issue:12

    Topics: Adult; Aged; Amino Acids; Cerebral Infarction; Erythrocytes; Female; gamma-Aminobutyric Acid; Humans

1978
[Effects of GABA and piracetam on the development of experimental cerebral infarction in rats and platelet aggregation in patients with cerebrovascular disorders].
    Biulleten' eksperimental'noi biologii i meditsiny, 1990, Volume: 110, Issue:8

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Brain; Cerebral Infarction; Cerebrovascular Disorders;

1990
Cerebral metabolism in man after acute stroke: new observations using localized proton NMR spectroscopy.
    Magnetic resonance in medicine, 1989, Volume: 9, Issue:1

    Topics: Adult; Aspartic Acid; Brain; Brain Ischemia; Cerebral Infarction; Cerebrovascular Disorders; gamma-A

1989
[A quantitative measurement of the cerebral infarct focus induced by arachidonate infusion and the relationship between measured values and stroke signs].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1988, Volume: 92, Issue:3

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Brain; Cerebral Infarction; Cerebrovascular Disorders;

1988
The effects of hyperglycaemia on changes during reperfusion following focal cerebral ischaemia in the cat.
    Journal of neurology, neurosurgery, and psychiatry, 1985, Volume: 48, Issue:7

    Topics: Animals; Blood Glucose; Brain Ischemia; Cats; Cerebral Cortex; Cerebral Infarction; Cerebrovascular

1985