gamma-aminobutyric acid has been researched along with Anhedonia in 6 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Anhedonia: Inability to experience pleasure due to impairment or dysfunction of normal psychological and neurobiological mechanisms. It is a symptom of many PSYCHOTIC DISORDERS (e.g., DEPRESSIVE DISORDER, MAJOR; and SCHIZOPHRENIA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Anhedonia was induced by chronic stress in male mice and assayed by preferences for sucrose and female urine (n = 5-7 mice/group)." | 8.12 | Negative Allosteric Modulation of Gamma-Aminobutyric Acid A Receptors at α5 Subunit-Containing Benzodiazepine Sites Reverses Stress-Induced Anhedonia and Weakened Synaptic Function in Mice. ( Georgiou, P; Gould, TD; Rudolph, U; Thompson, SM; Troppoli, TA; Zanos, P, 2022) |
| "Anhedonia was induced by chronic stress in male mice and assayed by preferences for sucrose and female urine (n = 5-7 mice/group)." | 5.72 | Negative Allosteric Modulation of Gamma-Aminobutyric Acid A Receptors at α5 Subunit-Containing Benzodiazepine Sites Reverses Stress-Induced Anhedonia and Weakened Synaptic Function in Mice. ( Georgiou, P; Gould, TD; Rudolph, U; Thompson, SM; Troppoli, TA; Zanos, P, 2022) |
| "Anhedonia was induced by chronic stress in male mice and assayed by preferences for sucrose and female urine (n = 5-7 mice/group)." | 4.12 | Negative Allosteric Modulation of Gamma-Aminobutyric Acid A Receptors at α5 Subunit-Containing Benzodiazepine Sites Reverses Stress-Induced Anhedonia and Weakened Synaptic Function in Mice. ( Georgiou, P; Gould, TD; Rudolph, U; Thompson, SM; Troppoli, TA; Zanos, P, 2022) |
| " We assessed fluoxetine's effects on motivated behaviors in pubescent female hamsters - anhedonia in the reward investigational preference (RIP) test as well as anxiety in the anxiety-related feeding/exploration conflict (AFEC) test." | 3.83 | Fluoxetine disrupts motivation and GABAergic signaling in adolescent female hamsters. ( DuBois, DW; Fincher, AS; Frye, GD; Henry, MM; Morgan, C; Shannonhouse, JL; Vela, AM; Wellman, PJ, 2016) |
| "Anhedonia was induced by chronic stress in male mice and assayed by preferences for sucrose and female urine (n = 5-7 mice/group)." | 1.72 | Negative Allosteric Modulation of Gamma-Aminobutyric Acid A Receptors at α5 Subunit-Containing Benzodiazepine Sites Reverses Stress-Induced Anhedonia and Weakened Synaptic Function in Mice. ( Georgiou, P; Gould, TD; Rudolph, U; Thompson, SM; Troppoli, TA; Zanos, P, 2022) |
| "Anhedonia, a core symptom of major depressive disorder (MDD) and highly variable among adolescents with MDD, may involve alterations in the major inhibitory amino acid neurotransmitter system of γ-aminobutyric acid (GABA)." | 1.38 | Anterior cingulate cortex γ-aminobutyric acid in depressed adolescents: relationship to anhedonia. ( Alonso, CM; Babb, JS; Ely, BA; Gabbay, V; Klein, RG; Mao, X; Panzer, AM; Shungu, DC, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Troppoli, TA | 1 |
| Zanos, P | 1 |
| Georgiou, P | 1 |
| Gould, TD | 1 |
| Rudolph, U | 1 |
| Thompson, SM | 1 |
| Ho, YC | 1 |
| Lin, TB | 1 |
| Hsieh, MC | 1 |
| Lai, CY | 1 |
| Chou, D | 1 |
| Chau, YP | 1 |
| Chen, GD | 1 |
| Peng, HY | 1 |
| Gabbay, V | 2 |
| Bradley, KA | 1 |
| Mao, X | 2 |
| Ostrover, R | 1 |
| Kang, G | 1 |
| Shungu, DC | 2 |
| Shao, B | 1 |
| Zhou, YL | 1 |
| Wang, H | 1 |
| Lin, YS | 1 |
| Shannonhouse, JL | 1 |
| DuBois, DW | 1 |
| Fincher, AS | 1 |
| Vela, AM | 1 |
| Henry, MM | 1 |
| Wellman, PJ | 1 |
| Frye, GD | 1 |
| Morgan, C | 1 |
| Klein, RG | 1 |
| Ely, BA | 1 |
| Babb, JS | 1 |
| Panzer, AM | 1 |
| Alonso, CM | 1 |
6 other studies available for gamma-aminobutyric acid and Anhedonia
| Article | Year |
|---|---|
Negative Allosteric Modulation of Gamma-Aminobutyric Acid A Receptors at α5 Subunit-Containing Benzodiazepine Sites Reverses Stress-Induced Anhedonia and Weakened Synaptic Function in Mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anhedonia; Animals; Benzodiazepines; Femal | 2022 |
Periaqueductal Gray Glutamatergic Transmission Governs Chronic Stress-Induced Depression.
Topics: Anhedonia; Animals; Behavior, Animal; Depression; Disease Models, Animal; gamma-Aminobutyric Acid; G | 2018 |
Anterior cingulate cortex γ-aminobutyric acid deficits in youth with depression.
Topics: Adolescent; Anhedonia; Brain; Child; Depression; Depressive Disorder, Major; Female; gamma-Aminobuty | 2017 |
The role of calcitonin gene-related peptide in post-stroke depression in chronic mild stress-treated ischemic rats.
Topics: Anhedonia; Animals; Antidepressive Agents; Brain Ischemia; Calcitonin Gene-Related Peptide; Chronic | 2015 |
Fluoxetine disrupts motivation and GABAergic signaling in adolescent female hamsters.
Topics: Anhedonia; Animals; Anxiety; Brain-Derived Neurotrophic Factor; Conflict, Psychological; Cricetinae; | 2016 |
Anterior cingulate cortex γ-aminobutyric acid in depressed adolescents: relationship to anhedonia.
Topics: Adolescent; Anhedonia; Case-Control Studies; Child; Cross-Sectional Studies; Depressive Disorder, Ma | 2012 |