gamma-aminobutyric acid has been researched along with Anesthesia in 116 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
| Excerpt | Relevance | Reference |
|---|---|---|
| " After standard premedication, 25 patients in each group received propofol, fentanyl, and local anesthesia at the operative site." | 9.11 | The analgesic effects of gabapentin in monitored anesthesia care for ear-nose-throat surgery. ( Karamanlioğlu, B; Memiş, D; Pamukçu, Z; Turan, A; Yağiz, R; Yavuz, E, 2004) |
| "The suitability of urethane anesthesia for physiopharmacological investigations is reviewed." | 8.77 | Suitability of urethane anesthesia for physiopharmacological investigations in various systems. Part 1: General considerations. ( Maggi, CA; Meli, A, 1986) |
| " Dialysis samples were collected from the pontine reticular formation during isoflurane anesthesia and wakefulness." | 7.74 | Gamma-aminobutyric acid-mediated neurotransmission in the pontine reticular formation modulates hypnosis, immobility, and breathing during isoflurane anesthesia. ( Baghdoyan, HA; Lydic, R; Vanini, G; Watson, CJ, 2008) |
| "Intravenous administration of 2-[2-methoxyethoxy]-ethyl 8-[cis-2-n-octylcyclopropyl]-octanoate (A2C) was found to disorder brain membranes but did not produce intoxication or anesthesia in mice." | 7.67 | Fluidization of brain membranes by A2C does not produce anesthesia and does not augment muscimol-stimulated 36Cl- influx. ( Allan, AM; Buck, KJ; Harris, RA, 1989) |
| "General anesthesia has long been used in clinical practice, but its precise pharmacological effects on neural circuits are not fully understood." | 5.91 | Dopamine D1-receptor-expressing pathway from the nucleus accumbens to ventral pallidum-mediated sevoflurane anesthesia in mice. ( Liang, X; Liu, C; Peng, Y; Shi, W; Yuan, C; Zhang, J; Zhang, Y, 2023) |
| "Isoflurane is a widely used anesthetic which safely and reversibly induces deep coma and associated burst suppression (BS) electroencephalographic patterns." | 5.35 | Cortical inhibition during burst suppression induced with isoflurane anesthesia. ( Amzica, F; Chever, O; Ferron, JF; Kroeger, D, 2009) |
| "Naloxone reversed respiratory paralysis and restored GABA close to control values in rat brain stem and cortex with no changes in caudate or cerebellum." | 5.29 | Evidence for involvement of amino acid neurotransmitters in anesthesia and naloxone induced reversal of respiratory paralysis. ( Rasheed, F; Suria, A, 1994) |
| "Patients undergoing craniotomy received either placebo (group D) or gabapentin (600 mg) (group GD) premedication orally, 2 hours before induction of anesthesia." | 5.17 | The effect of gabapentin premedication on postoperative nausea, vomiting, and pain in patients on preoperative dexamethasone undergoing craniotomy for intracranial tumors. ( Misra, S; Parthasarathi, G; Vilanilam, GC, 2013) |
| " After standard premedication, 25 patients in each group received propofol, fentanyl, and local anesthesia at the operative site." | 5.11 | The analgesic effects of gabapentin in monitored anesthesia care for ear-nose-throat surgery. ( Karamanlioğlu, B; Memiş, D; Pamukçu, Z; Turan, A; Yağiz, R; Yavuz, E, 2004) |
| "The suitability of urethane anesthesia for physiopharmacological investigations is reviewed." | 4.77 | Suitability of urethane anesthesia for physiopharmacological investigations in various systems. Part 1: General considerations. ( Maggi, CA; Meli, A, 1986) |
| "Our previous clinical trial showed that etomidate requirements to reach an appropriate level of anesthesia in patients with obstructive jaundice were reduced, which means that these patients are more sensitive to etomidate." | 4.31 | Bilirubin potentiates etomidate-induced sedation by enhancing GABA-induced currents after bile duct ligation. ( Gao, H; Hu, GX; Jiao, YF; Song, JC; Song, JG; Yu, WF; Zhao, Q, 2023) |
| " Anesthesia sensitivity to etomidate was determined by the time to loss of righting reflex (LORR)." | 4.31 | Bilirubin potentiates etomidate-induced sedation by enhancing GABA-induced currents after bile duct ligation. ( Gao, H; Hu, GX; Jiao, YF; Song, JC; Song, JG; Yu, WF; Zhao, Q, 2023) |
| "The present study aimed to investigate the effects of different dosages of propofol, that induced different depths of anesthesia, on the local activity and connectivity of nuclei within the cortico-reticulo-thalamic loops, as well as the release of amino acids in those nuclei." | 3.91 | Propofol inhibits the local activity and connectivity of nuclei in the cortico-reticulo-thalamic loop in rats. ( Mi, W; Wang, W; Yang, J; Yong, Z; Yuan, W; Zhang, H, 2019) |
| "ApEn was more significantly reduced in the cortex than in the subcortical nuclei from awake to deep anesthesia state induced by propofol, and C-ApEn was also more significantly reduced between cortical nucleus and subcortical nucleus than between subcortical nuclei from awake to deep anesthesia state induced by propofol." | 3.91 | Propofol inhibits the local activity and connectivity of nuclei in the cortico-reticulo-thalamic loop in rats. ( Mi, W; Wang, W; Yang, J; Yong, Z; Yuan, W; Zhang, H, 2019) |
| "The cortex rather than the subcortical structures, and the cortex-subcortical connectivity instead of subcortical connectivity might be the more vulnerable targets of propofol during anesthesia." | 3.91 | Propofol inhibits the local activity and connectivity of nuclei in the cortico-reticulo-thalamic loop in rats. ( Mi, W; Wang, W; Yang, J; Yong, Z; Yuan, W; Zhang, H, 2019) |
| " We hypothesized that the volatile anesthetic sevoflurane (SEVO) attenuates lung inflammation through activation of lung epithelial GABA(A) receptors." | 3.78 | Effects of anesthetic regimes on inflammatory responses in a rat model of acute lung injury. ( Fortis, S; Haitsma, JJ; Lu, WY; Mazer, CD; Parotto, M; Slutsky, AS; Spieth, PM; Zhang, H; Zhong, N, 2012) |
| "Isoflurane anesthesia was physiologically well tolerated by the dams." | 3.77 | Rats exposed to isoflurane in utero during early gestation are behaviorally abnormal as adults. ( Baxter, MG; Crosby, G; Culley, DJ; Keel, PK; Palanisamy, A; Xie, Z, 2011) |
| "Rats exposed to isoflurane in utero at a time that corresponds to the second trimester in humans have impaired spatial memory acquisition and reduced anxiety, compared with controls." | 3.77 | Rats exposed to isoflurane in utero during early gestation are behaviorally abnormal as adults. ( Baxter, MG; Crosby, G; Culley, DJ; Keel, PK; Palanisamy, A; Xie, Z, 2011) |
| "The mechanism of prolongation of sleeping (anesthesia) time after phenobarbital (PB) treatment was assessed in mice with ethionine (ET)-induced liver disorders (ET-treated group)." | 3.69 | Sleeping time after phenobarbital treatment and the brain levels of gamma-aminobutyric acid and phenobarbital at the regaining of righting response point in ethionine-induced liver-disordered mice. ( Kawai, Y; Noguchi, M, 1996) |
| "In order to identify lasting alterations in gamma-aminobutyric acid (GABA) neurons in the kindling model of epilepsy, immunocytochemical techniques were used to quantify the number of GABA-immunoreactive (IR) neurons in different regions of the hippocampal formation (HCF) of amygdala-kindled rats, 40 days after the last fully kindled seizure." | 3.69 | Immunocytochemical localization of GABA immunoreactivity in dentate granule cells of normal and kindled rats. ( Ebert, U; Lehmann, H; Löscher, W, 1996) |
| "Using receptors expressed from mouse brain mRNA in Xenopus oocytes, we found that enhancement of type A gamma-aminobutyric acid (GABAA) receptor-gated Cl- channel response is a common action of structurally diverse anesthetics, suggesting that the GABAA receptor plays an important role in anesthesia." | 3.68 | Molecular determinants of general anesthetic action: role of GABAA receptor structure. ( Harris, RA; Lin, LH; Whiting, P, 1993) |
| " In the absence of anesthesia, functional properties of the MSA neurons were significantly different from those observed in the urethane-anesthetized rat (higher variability of discharge rate, lower percentage of rhythmically bursting neurons)." | 3.68 | Iontophoretic study of medial septal neurons in the unanesthetized rat. ( Bassant, MH; Lamour, Y; Lee, BH, 1991) |
| "Intravenous administration of 2-[2-methoxyethoxy]-ethyl 8-[cis-2-n-octylcyclopropyl]-octanoate (A2C) was found to disorder brain membranes but did not produce intoxication or anesthesia in mice." | 3.67 | Fluidization of brain membranes by A2C does not produce anesthesia and does not augment muscimol-stimulated 36Cl- influx. ( Allan, AM; Buck, KJ; Harris, RA, 1989) |
| "The effects of several convulsants and diazepam on pentobarbital-stimulated gastric acid secretion were studied in the perfused stomach of rats under urethane anesthesia." | 3.67 | Possible involvement of the central GABAergic system in pentobarbital-stimulated gastric acid secretion in the perfused rat stomach preparation. ( Lin, WC; Watanabe, K; Yano, S, 1988) |
| " For instance, [3H]gamma-aminobutyric acid release in the dorsal raphe was enhanced by halothane anesthesia." | 3.66 | Chlordiazepoxide reduces in vivo serotonin release in the basal ganglia of encéphale isolé but not anesthetized cats: evidence for a dorsal raphe site of action. ( Blas, C; Ferron, A; Glowinski, J; Soubrie, P, 1983) |
| "A dosage of 600 mg of gabapentin plus 4 mg of dexamethasone significantly reduced the 24-hour incidence of nausea and PONV." | 2.78 | The effect of gabapentin premedication on postoperative nausea, vomiting, and pain in patients on preoperative dexamethasone undergoing craniotomy for intracranial tumors. ( Misra, S; Parthasarathi, G; Vilanilam, GC, 2013) |
| "General anesthesia has long been used in clinical practice, but its precise pharmacological effects on neural circuits are not fully understood." | 1.91 | Dopamine D1-receptor-expressing pathway from the nucleus accumbens to ventral pallidum-mediated sevoflurane anesthesia in mice. ( Liang, X; Liu, C; Peng, Y; Shi, W; Yuan, C; Zhang, J; Zhang, Y, 2023) |
| "Tiagabine-treated rats were indistinguishable (P > 0." | 1.42 | Effects of γ-Aminobutyric acid transporter 1 inhibition by tiagabine on brain glutamate and γ-Aminobutyric acid metabolism in the anesthetized rat In vivo. ( Behar, KL; de Graaf, RA; Patel, AB; Rothman, DL, 2015) |
| "Isoflurane anesthesia was physiologically well tolerated by the dams." | 1.37 | Rats exposed to isoflurane in utero during early gestation are behaviorally abnormal as adults. ( Baxter, MG; Crosby, G; Culley, DJ; Keel, PK; Palanisamy, A; Xie, Z, 2011) |
| " After IV administration, the mean +/- SEM apparent volume of the central compartment, apparent volume of distribution at steady state, and clearance and the harmonic mean +/- jackknife pseudo-SD for terminal half-life were 90." | 1.36 | Pharmacokinetics of gabapentin in cats. ( Ilkiw, JE; Pypendop, BH; Siao, KT, 2010) |
| "Gabapentin was administered IV (4 mg/kg) or orally (10 mg/kg) in a crossover randomized design." | 1.36 | Pharmacokinetics of gabapentin in cats. ( Ilkiw, JE; Pypendop, BH; Siao, KT, 2010) |
| "Isoflurane is a widely used anesthetic which safely and reversibly induces deep coma and associated burst suppression (BS) electroencephalographic patterns." | 1.35 | Cortical inhibition during burst suppression induced with isoflurane anesthesia. ( Amzica, F; Chever, O; Ferron, JF; Kroeger, D, 2009) |
| "Sound induced convulsions in DBA/2 mice were dose-dependently inhibited by all compounds (administered intraperitoneal, i." | 1.31 | GABA-level increasing and anticonvulsant effects of three different GABA uptake inhibitors. ( Dalby, NO, 2000) |
| " Chronic administration of 2." | 1.30 | Adaptive responses of gamma-aminobutyric acid neurons in the ventral tegmental area to chronic ethanol. ( Criado, JR; Gallegos, RA; Henriksen, SJ; Lee, RS; Steffensen, SC, 1999) |
| "Naloxone reversed respiratory paralysis and restored GABA close to control values in rat brain stem and cortex with no changes in caudate or cerebellum." | 1.29 | Evidence for involvement of amino acid neurotransmitters in anesthesia and naloxone induced reversal of respiratory paralysis. ( Rasheed, F; Suria, A, 1994) |
| "Muscimol was without effect in pylorus-ligated rats, whereas baclofen produced a significant decrease in acid secretion, which was fully prevented by phaclofen." | 1.28 | Central GABAA excitatory and GABAB inhibitory receptors regulate gastric acid secretion in rats. ( Bernardini, MC; Blandizzi, C; Del Tacca, M, 1990) |
| "Pretreatment with bicuculline, a GABAA-receptor antagonist, in the doses of 1 and 3 mg/kg, subcutaneously, had no influence on the gastric acid response to baclofen." | 1.28 | Effects of GABA antagonists and structural GABA analogues on baclofen stimulated gastric acid secretion in the rat. ( Goto, Y; Hara, N; Hara, Y, 1990) |
| "Reserpine pretreatment lowered resting cardiovascular parameters." | 1.27 | Differences in cardiovascular responses to peripherally administered GABA as influenced by basal conditions and type of anaesthesia. ( Giuliani, S; Maggi, CA; Meli, A, 1986) |
| "gamma-aminobutyric acid (GABA) were investigated in guinea-pigs anaesthetized with barbitone or urethane." | 1.27 | Differences in cardiovascular responses to peripherally administered GABA as influenced by basal conditions and type of anaesthesia. ( Giuliani, S; Maggi, CA; Meli, A, 1986) |
| "Intraperitoneal injection of diazepam in moderate dosage (1--10mg/kg) to rats caused a decrease in dopa and 5-hydroxytryptophan (5-HTP) formation, measured as the accumulation of these intermediates induced by inhibition of the aromatic L-aminoacid decarboxylase by means of NSD 1015 (3-hydroxybenzylhydrazine (HCl), in limbic forebrain, striatum and the remaining hemisphere portion." | 1.26 | On the mode of action of diazepam on brain catecholamine metabolism. ( Biswas, B; Carlsson, A, 1978) |
| "gamma-Aminobutyric acid was inactive and meprobamate caused flaccid paralysis with loss of the righting reflex." | 1.24 | THE ACTION OF SODIUM 4-HYDROXYBUTYRATE ON SPINAL REFLEXES. ( BASIL, B; BLAIR, AM; HOLMES, SW, 1964) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (28.45) | 18.7374 |
| 1990's | 28 (24.14) | 18.2507 |
| 2000's | 26 (22.41) | 29.6817 |
| 2010's | 25 (21.55) | 24.3611 |
| 2020's | 4 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, J | 1 |
| Peng, Y | 1 |
| Liu, C | 2 |
| Zhang, Y | 4 |
| Liang, X | 1 |
| Yuan, C | 1 |
| Shi, W | 1 |
| Gao, H | 1 |
| Zhao, Q | 1 |
| Song, JG | 1 |
| Hu, GX | 1 |
| Yu, WF | 1 |
| Jiao, YF | 1 |
| Song, JC | 1 |
| Li, Y | 2 |
| Hari, K | 1 |
| Lucas-Osma, AM | 1 |
| Fenrich, KK | 1 |
| Bennett, DJ | 1 |
| Hammar, I | 1 |
| Jankowska, E | 1 |
| Shi, F | 1 |
| Fu, B | 1 |
| Luo, T | 1 |
| Zhang, L | 1 |
| Yu, S | 1 |
| Yu, T | 1 |
| Yeganeh, F | 1 |
| Nasimi, A | 1 |
| Hatam, M | 1 |
| Chang, CH | 1 |
| Grace, AA | 1 |
| Marvin, JS | 1 |
| Shimoda, Y | 1 |
| Magloire, V | 1 |
| Leite, M | 1 |
| Kawashima, T | 1 |
| Jensen, TP | 1 |
| Kolb, I | 1 |
| Knott, EL | 1 |
| Novak, O | 1 |
| Podgorski, K | 1 |
| Leidenheimer, NJ | 1 |
| Rusakov, DA | 1 |
| Ahrens, MB | 1 |
| Kullmann, DM | 1 |
| Looger, LL | 1 |
| Yang, J | 1 |
| Wang, W | 1 |
| Yong, Z | 1 |
| Yuan, W | 1 |
| Zhang, H | 2 |
| Mi, W | 1 |
| Hopkins, SC | 1 |
| Zhao, FY | 1 |
| Bowen, CA | 1 |
| Fang, X | 1 |
| Wei, H | 1 |
| Heffernan, ML | 1 |
| Spear, KL | 1 |
| Spanswick, DC | 1 |
| Varney, MA | 1 |
| Large, TH | 1 |
| Misra, S | 1 |
| Parthasarathi, G | 1 |
| Vilanilam, GC | 1 |
| Chamaraux-Tran, TN | 1 |
| Levy, F | 1 |
| Zappaterra, M | 1 |
| Goetz, J | 1 |
| Goichot, B | 1 |
| Steib, A | 1 |
| Sandiego, CM | 1 |
| Jin, X | 1 |
| Mulnix, T | 1 |
| Fowles, K | 1 |
| Labaree, D | 1 |
| Ropchan, J | 1 |
| Huang, Y | 1 |
| Cosgrove, K | 1 |
| Castner, SA | 1 |
| Williams, GV | 1 |
| Wells, L | 1 |
| Rabiner, EA | 1 |
| Carson, RE | 1 |
| Rashiq, S | 1 |
| Dick, BD | 1 |
| Wu, CL | 1 |
| Shih, MF | 1 |
| Lee, PT | 1 |
| Chiang, AS | 1 |
| Patel, AB | 1 |
| de Graaf, RA | 2 |
| Rothman, DL | 2 |
| Behar, KL | 2 |
| Crociolli, GC | 1 |
| Cassu, RN | 1 |
| Barbero, RC | 1 |
| Rocha, TL | 1 |
| Gomes, DR | 1 |
| Nicácio, GM | 1 |
| Herrera, CG | 1 |
| Cadavieco, MC | 1 |
| Jego, S | 1 |
| Ponomarenko, A | 1 |
| Korotkova, T | 1 |
| Adamantidis, A | 1 |
| Chen, SL | 1 |
| Huang, YH | 1 |
| Kao, YL | 1 |
| Chen, GD | 1 |
| Cheng, CL | 2 |
| Peng, HY | 2 |
| Liao, JM | 2 |
| Huang, PC | 1 |
| Tsai, SJ | 1 |
| Lin, TB | 2 |
| Vanini, G | 1 |
| Watson, CJ | 1 |
| Lydic, R | 1 |
| Baghdoyan, HA | 1 |
| Ferron, JF | 1 |
| Kroeger, D | 1 |
| Chever, O | 1 |
| Amzica, F | 1 |
| Burke, SM | 1 |
| Shorten, GD | 1 |
| Hoffmann, U | 1 |
| Dileköz, E | 1 |
| Kudo, C | 1 |
| Ayata, C | 1 |
| Siao, KT | 1 |
| Pypendop, BH | 1 |
| Ilkiw, JE | 1 |
| Canning, BJ | 1 |
| Mori, N | 1 |
| Zhou, ZW | 1 |
| Shu, Y | 1 |
| Li, M | 1 |
| Guo, X | 1 |
| Pac-Soo, C | 1 |
| Maze, M | 1 |
| Ma, D | 1 |
| Palanisamy, A | 1 |
| Baxter, MG | 1 |
| Keel, PK | 1 |
| Xie, Z | 1 |
| Crosby, G | 1 |
| Culley, DJ | 1 |
| Jiang, L | 1 |
| Mason, GF | 1 |
| Yanovsky, Y | 1 |
| Schubring, S | 1 |
| Fleischer, W | 1 |
| Gisselmann, G | 1 |
| Zhu, XR | 1 |
| Lübbert, H | 1 |
| Hatt, H | 1 |
| Rudolph, U | 1 |
| Haas, HL | 1 |
| Sergeeva, OA | 1 |
| El Hage, M | 1 |
| Ferrier, B | 1 |
| Baverel, G | 1 |
| Martin, G | 1 |
| McCarthy, MM | 1 |
| Ching, S | 1 |
| Whittington, MA | 1 |
| Kopell, N | 1 |
| Fortis, S | 1 |
| Spieth, PM | 1 |
| Lu, WY | 1 |
| Parotto, M | 1 |
| Haitsma, JJ | 1 |
| Slutsky, AS | 1 |
| Zhong, N | 1 |
| Mazer, CD | 1 |
| Shadan, S | 1 |
| Mascias, P | 1 |
| Scheede, M | 2 |
| Bloms-Funke, P | 2 |
| Chizh, B | 1 |
| Moser, EI | 1 |
| Klausberger, T | 1 |
| Magill, PJ | 1 |
| Márton, LF | 1 |
| Roberts, JD | 1 |
| Cobden, PM | 1 |
| Buzsáki, G | 1 |
| Somogyi, P | 1 |
| Björnström, K | 1 |
| Eintrei, C | 1 |
| Rodríguez, M | 1 |
| Pereda, E | 1 |
| González, J | 1 |
| Abdala, P | 1 |
| Obeso, JA | 1 |
| MATSUZAKI, H | 1 |
| KUMEI, K | 1 |
| BASIL, B | 1 |
| BLAIR, AM | 1 |
| HOLMES, SW | 1 |
| BHATTACHARYA, SS | 1 |
| KISHOR, K | 1 |
| SAXENA, PN | 1 |
| BHARGAVA, KP | 1 |
| Bujok, G | 1 |
| Knapik, P | 1 |
| Osaka, T | 1 |
| Freye, E | 1 |
| Levy, JV | 1 |
| Partecke, L | 1 |
| Soto, C | 1 |
| Aguilar, J | 1 |
| Martín-Cora, F | 1 |
| Rivadulla, C | 1 |
| Canedo, A | 1 |
| Yelmen, KN | 1 |
| Turan, A | 2 |
| Memiş, D | 2 |
| Karamanlioğlu, B | 2 |
| Yağiz, R | 1 |
| Pamukçu, Z | 1 |
| Yavuz, E | 1 |
| Seker, S | 1 |
| Türe, M | 1 |
| Masri, R | 1 |
| Trageser, JC | 1 |
| Bezdudnaya, T | 1 |
| Keller, A | 1 |
| Brack, KE | 1 |
| Lovick, TA | 1 |
| Chen, KJ | 1 |
| Chen, CH | 1 |
| Ho, YC | 1 |
| Liou, JT | 1 |
| Tung, KC | 1 |
| Hsu, TH | 1 |
| Reiner, K | 1 |
| Sukhotinsky, I | 1 |
| Devor, M | 1 |
| Dhumal, VR | 1 |
| Gulati, OD | 1 |
| Bhavsar, VH | 1 |
| Billingsley, ML | 2 |
| Suria, A | 2 |
| Bowdler, JM | 1 |
| Green, AR | 1 |
| Soubrie, P | 1 |
| Blas, C | 1 |
| Ferron, A | 1 |
| Glowinski, J | 1 |
| Incze, F | 1 |
| Lichtenberger, G | 1 |
| Medgyesy, M | 1 |
| Vámos, Z | 1 |
| Miñano, J | 1 |
| Durán, JA | 1 |
| Serrano, JS | 1 |
| Hernández, J | 1 |
| Tsoucaris-Kupfer, D | 1 |
| Liblau, L | 1 |
| Legrand, M | 1 |
| Schmitt, H | 1 |
| Watanabe, K | 2 |
| Watanabe, H | 1 |
| Goto, Y | 4 |
| Shimizu, M | 1 |
| Maeda-Hagiwara, M | 1 |
| Krishnan, H | 1 |
| Baquer, NZ | 1 |
| Singh, R | 1 |
| Moroni, F | 2 |
| Corradetti, R | 2 |
| Casamenti, F | 2 |
| Moneti, G | 2 |
| Pepeu, G | 2 |
| Champagnat, J | 1 |
| Denavit-Saubié, M | 1 |
| Moyanova, S | 1 |
| Rondouin, G | 1 |
| Boudinot, E | 1 |
| Vadora, E | 1 |
| Bacchi Modena, A | 1 |
| Lombardozzi, L | 1 |
| Menon, MK | 1 |
| Clark, WG | 1 |
| Vivonia, C | 1 |
| Persson, B | 1 |
| Lillrank, SM | 1 |
| O'Connor, WT | 3 |
| Oja, SS | 1 |
| Ungerstedt, U | 3 |
| Lin, LH | 1 |
| Whiting, P | 1 |
| Harris, RA | 2 |
| Rasheed, F | 1 |
| Tarakanov, IA | 1 |
| Kurambaev, IaK | 1 |
| Safonov, VA | 1 |
| Morari, M | 1 |
| Fuxe, K | 1 |
| McLemore, GL | 1 |
| Severs, WB | 1 |
| Noguchi, M | 1 |
| Kawai, Y | 1 |
| del Carmen García, M | 1 |
| Enero, MA | 1 |
| Celuch, SM | 1 |
| Lehmann, H | 1 |
| Ebert, U | 2 |
| Löscher, W | 2 |
| Nakahiro, M | 1 |
| Arakawa, O | 1 |
| Nishimura, T | 1 |
| Narahashi, T | 1 |
| Gardner, CR | 1 |
| Hussain, S | 1 |
| Pringle, A | 1 |
| Bagust, J | 1 |
| Walker, RJ | 1 |
| Li, HS | 1 |
| Monhemius, R | 1 |
| Simpson, BA | 1 |
| Roberts, MH | 1 |
| Honjo, K | 2 |
| Goshima, Y | 2 |
| Miyamae, T | 2 |
| Misu, Y | 2 |
| Gernert, M | 1 |
| Manunta, Y | 1 |
| Edeline, JM | 1 |
| Gallegos, RA | 1 |
| Lee, RS | 1 |
| Criado, JR | 1 |
| Henriksen, SJ | 1 |
| Steffensen, SC | 1 |
| Yang, CS | 1 |
| Tsai, PJ | 1 |
| Chen, WY | 1 |
| Tsai, WJ | 1 |
| Kuo, JS | 1 |
| Soulière, F | 1 |
| Urbain, N | 1 |
| Gervasoni, D | 1 |
| Schmitt, P | 1 |
| Guillemort, C | 1 |
| Fort, P | 1 |
| Renaud, B | 1 |
| Luppi, PH | 1 |
| Chouvet, G | 1 |
| Chizh, BA | 1 |
| Schlütz, H | 1 |
| Dalby, NO | 1 |
| Arts, MP | 1 |
| De Zeeuw, CI | 1 |
| Lips, J | 1 |
| Rosbak, E | 1 |
| Simpson, JI | 1 |
| Hupé, JM | 1 |
| James, AC | 1 |
| Girard, P | 1 |
| Bullier, J | 1 |
| Yamada, K | 1 |
| Wada, E | 1 |
| Wada, K | 1 |
| Molyneaux, BJ | 1 |
| Hasselmo, ME | 1 |
| Angel, A | 1 |
| Clarke, KA | 1 |
| Dewhurst, DG | 1 |
| Biswas, B | 1 |
| Carlsson, A | 1 |
| Myslobodsky, MS | 1 |
| Ackermann, RF | 1 |
| Golovchinsky, V | 1 |
| Engel, J | 1 |
| Antonaccio, MJ | 1 |
| Taylor, DG | 1 |
| Dashwood, MR | 1 |
| Feldberg, W | 1 |
| Quevedo, J | 1 |
| Eguibar, JR | 1 |
| Jiménez, I | 1 |
| Rudomin, P | 1 |
| Heinricher, MM | 1 |
| Kaplan, HJ | 1 |
| Lee, BH | 1 |
| Lamour, Y | 1 |
| Bassant, MH | 1 |
| Lantin le Boulch, N | 1 |
| Truong-Ngoc, NA | 1 |
| Gauchy, C | 1 |
| Besson, MJ | 1 |
| Hara, N | 3 |
| Hara, Y | 3 |
| Natsume, Y | 2 |
| Del Tacca, M | 1 |
| Blandizzi, C | 1 |
| Bernardini, MC | 1 |
| Kaneko, T | 1 |
| Hicks, TP | 1 |
| Osborne, PG | 1 |
| Drew, KL | 1 |
| Albertson, TE | 1 |
| Joy, RM | 1 |
| Buck, KJ | 1 |
| Allan, AM | 1 |
| Maggi, CA | 4 |
| Giuliani, S | 3 |
| Meli, A | 4 |
| Becquet, D | 1 |
| Faudon, M | 1 |
| Hery, F | 1 |
| Lin, WC | 1 |
| Yano, S | 1 |
| Capasso, M | 1 |
| Frolov, VA | 1 |
| Bilibin, DP | 1 |
| Shevelev, OA | 1 |
| Chalabian, ZhA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Gabapentin Regimens and Their Effects on Opioid Consumption[NCT03334903] | Phase 4 | 77 participants (Actual) | Interventional | 2018-05-15 | Completed | ||
| Comparison of Oral Lamotrigine Versus Pregabalin for Control of Acute and Chronic Pain Following Modified Radical Mastectomy: Controlled Double-blind Study[NCT03419949] | 0 participants | Expanded Access | Available | ||||
| A Prospective Randomized Double Blind Trial to Assess the Effect of a Single Preoperative Dose of Gabapentin on Postoperative Opioid Consumption in Patients Undergoing Rhinoplasty[NCT03498261] | Phase 1 | 50 participants (Actual) | Interventional | 2018-01-30 | Active, not recruiting | ||
| Efficacy of Preoperative Administration of Gabapentin in Managing Intraoperative and Postoperative Pain From Third Molar Extractions.[NCT04860141] | Phase 4 | 98 participants (Anticipated) | Interventional | 2021-06-16 | Recruiting | ||
| Comparison of Oral Gabapentin and Pregabalin in Postoperative Pain Control After Photorefractive Keratectomy: a Prospective, Randomized Study.[NCT00954187] | 8 participants (Actual) | Interventional | 2009-11-30 | Terminated (stopped due to PI left institution) | |||
| Effect of Preoperative Pregabalin on Propofol Induction Dose[NCT01158859] | Phase 4 | 50 participants (Anticipated) | Interventional | 2010-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Surgical site pain. Scale 0-10, with 0 best and 10 worst (NCT03334903)
Timeframe: 2-3 months after surgery (at 2nd postoperative appointment)
| Intervention | score on 10-point scale (Mean) |
|---|---|
| Standard of Care | 2.26 |
| Postoperative Gabapentin Regimen | 2.46 |
Surgical site pain. Scale 0-10, with 0 best and 10 worst. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).
| Intervention | score on a 10-point scale (Mean) |
|---|---|
| Standard of Care | 3.84 |
| Postoperative Gabapentin Regimen | 3.54 |
Sleep quality. Scale 0-10 with 0 worst and 10 best. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).
| Intervention | score on a 10-point scale (Mean) |
|---|---|
| Standard of Care | 5.73 |
| Postoperative Gabapentin Regimen | 6.38 |
Nausea. Scale 0-10, with 0 best and 10 worst. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).
| Intervention | score on a 10-point scale (Mean) |
|---|---|
| Standard of Care | 0.36 |
| Postoperative Gabapentin Regimen | 0.17 |
Satisfaction. Scale 0-10 with 0 worst and 10 best. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).
| Intervention | score on a 10-point scale (Mean) |
|---|---|
| Standard of Care | 7.83 |
| Postoperative Gabapentin Regimen | 8.48 |
Number of days until patients are finished consuming opioid medications after discharge. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).
| Intervention | days (Mean) |
|---|---|
| Standard of Care | 14.8 |
| Postoperative Gabapentin Regimen | 18.7 |
Mean opioid consumption, measured in mg of morphine equivalents. (NCT03334903)
Timeframe: 2-3 months following surgery (total amount measured at second postoperative appointment; means assessed afterwards).
| Intervention | morphine equivalents (Mean) |
|---|---|
| Standard of Care | 287.0 |
| Postoperative Gabapentin Regimen | 281.1 |
3 reviews available for gamma-aminobutyric acid and Anesthesia
| Article | Year |
|---|---|
Post-surgical pain syndromes: a review for the non-pain specialist.
Topics: Age Factors; Amines; Analgesics; Anesthesia; Anesthetics; Anesthetics, Local; Animals; Chronic Pain; | 2014 |
Dynamical changes in neurological diseases and anesthesia.
Topics: Anesthesia; Anesthetics; gamma-Aminobutyric Acid; Humans; Models, Neurological; Nerve Net; Nervous S | 2012 |
Suitability of urethane anesthesia for physiopharmacological investigations in various systems. Part 1: General considerations.
Topics: Acetylcholine; Adrenal Medulla; Anesthesia; Animals; Brain; Catecholamines; Cerebral Cortex; Dose-Re | 1986 |
5 trials available for gamma-aminobutyric acid and Anesthesia
| Article | Year |
|---|---|
The effect of gabapentin premedication on postoperative nausea, vomiting, and pain in patients on preoperative dexamethasone undergoing craniotomy for intracranial tumors.
Topics: Adult; Amines; Anesthesia; Anti-Inflammatory Agents; Brain Neoplasms; Craniotomy; Cyclohexanecarboxy | 2013 |
Perioperative pregabalin improves pain and functional outcomes 3 months after lumbar discectomy.
Topics: Adolescent; Adult; Analgesics; Anesthesia; Diskectomy; DNA; Double-Blind Method; Electric Stimulatio | 2010 |
Use of gabapentin for attenuation of symptoms following rapid opiate detoxification (ROD)--correlation with neurophysiological parameters--.
Topics: Acetates; Adult; Amines; Anesthesia; Anesthetics, Intravenous; Cyclohexanecarboxylic Acids; Electric | 2004 |
The analgesic effects of gabapentin in monitored anesthesia care for ear-nose-throat surgery.
Topics: Acetates; Adult; Amines; Analgesics; Anesthesia; Anesthesia, Intravenous; Anesthetics, Intravenous; | 2004 |
The analgesic effects of gabapentin in monitored anesthesia care for ear-nose-throat surgery.
Topics: Acetates; Adult; Amines; Analgesics; Anesthesia; Anesthesia, Intravenous; Anesthetics, Intravenous; | 2004 |
The analgesic effects of gabapentin in monitored anesthesia care for ear-nose-throat surgery.
Topics: Acetates; Adult; Amines; Analgesics; Anesthesia; Anesthesia, Intravenous; Anesthetics, Intravenous; | 2004 |
The analgesic effects of gabapentin in monitored anesthesia care for ear-nose-throat surgery.
Topics: Acetates; Adult; Amines; Analgesics; Anesthesia; Anesthesia, Intravenous; Anesthetics, Intravenous; | 2004 |
The analgesic effects of gabapentin in monitored anesthesia care for ear-nose-throat surgery.
Topics: Acetates; Adult; Amines; Analgesics; Anesthesia; Anesthesia, Intravenous; Anesthetics, Intravenous; | 2004 |
The analgesic effects of gabapentin in monitored anesthesia care for ear-nose-throat surgery.
Topics: Acetates; Adult; Amines; Analgesics; Anesthesia; Anesthesia, Intravenous; Anesthetics, Intravenous; | 2004 |
The analgesic effects of gabapentin in monitored anesthesia care for ear-nose-throat surgery.
Topics: Acetates; Adult; Amines; Analgesics; Anesthesia; Anesthesia, Intravenous; Anesthetics, Intravenous; | 2004 |
The analgesic effects of gabapentin in monitored anesthesia care for ear-nose-throat surgery.
Topics: Acetates; Adult; Amines; Analgesics; Anesthesia; Anesthesia, Intravenous; Anesthetics, Intravenous; | 2004 |
The analgesic effects of gabapentin in monitored anesthesia care for ear-nose-throat surgery.
Topics: Acetates; Adult; Amines; Analgesics; Anesthesia; Anesthesia, Intravenous; Anesthetics, Intravenous; | 2004 |
Gabapentin reduces cardiovascular responses to laryngoscopy and tracheal intubation.
Topics: Administration, Oral; Adult; Amines; Anesthesia; Blood Pressure; Cardiovascular Surgical Procedures; | 2006 |
108 other studies available for gamma-aminobutyric acid and Anesthesia
| Article | Year |
|---|---|
Dopamine D1-receptor-expressing pathway from the nucleus accumbens to ventral pallidum-mediated sevoflurane anesthesia in mice.
Topics: Anesthesia; Animals; Basal Forebrain; Calcium; Dopamine; Dopaminergic Neurons; gamma-Aminobutyric Ac | 2023 |
Bilirubin potentiates etomidate-induced sedation by enhancing GABA-induced currents after bile duct ligation.
Topics: Anesthesia; Animals; Bile Ducts; Bilirubin; Etomidate; gamma-Aminobutyric Acid; Humans; Jaundice, Ob | 2023 |
Branching points of primary afferent fibers are vital for the modulation of fiber excitability by epidural DC polarization and by GABA in the rat spinal cord.
Topics: Anesthesia; Animals; Electric Stimulation; Electrophysiological Phenomena; Epidural Space; Female; G | 2020 |
GABA
Topics: Anesthesia; Animals; Basal Forebrain; Electroencephalography; gamma-Aminobutyric Acid; Muscimol; Pro | 2022 |
Interaction of GABA and norepinephrine in the lateral division of the bed nucleus of the stria terminals in anesthetized rat, correlating single-unit and cardiovascular responses.
Topics: Anesthesia; Animals; Blood Pressure; Cardiovascular System; gamma-Aminobutyric Acid; Heart Rate; Mal | 2017 |
Inhibitory Modulation of Orbitofrontal Cortex on Medial Prefrontal Cortex-Amygdala Information Flow.
Topics: Amygdala; Anesthesia; Animals; Baclofen; Bicuculline; Electric Stimulation; Emotions; Excitatory Ami | 2018 |
A genetically encoded fluorescent sensor for in vivo imaging of GABA.
Topics: Anesthesia; Animals; Animals, Genetically Modified; Biosensing Techniques; Brain; Female; gamma-Amin | 2019 |
Propofol inhibits the local activity and connectivity of nuclei in the cortico-reticulo-thalamic loop in rats.
Topics: Anesthesia; Animals; Electroencephalography; gamma-Aminobutyric Acid; Propofol; Rats; Rats, Wistar; | 2019 |
Pharmacodynamic effects of a D-amino acid oxidase inhibitor indicate a spinal site of action in rat models of neuropathic pain.
Topics: Amines; Analgesics; Anesthesia; Animals; Behavior, Animal; Constriction, Pathologic; Cyclohexanecarb | 2013 |
Cardiac surgery and C1-inhibitor deficiency.
Topics: Aged, 80 and over; Amines; Analgesics; Anesthesia; Angioedemas, Hereditary; Antifibrinolytic Agents; | 2014 |
Awake nonhuman primate brain PET imaging with minimal head restraint: evaluation of GABAA-benzodiazepine binding with 11C-flumazenil in awake and anesthetized animals.
Topics: Anesthesia; Animals; Benzodiazepines; Brain; Carbon Radioisotopes; Female; Flumazenil; gamma-Aminobu | 2013 |
An octopamine-mushroom body circuit modulates the formation of anesthesia-resistant memory in Drosophila.
Topics: Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Anesthesia; Animals; Animals, Genetically M | 2013 |
Effects of γ-Aminobutyric acid transporter 1 inhibition by tiagabine on brain glutamate and γ-Aminobutyric acid metabolism in the anesthetized rat In vivo.
Topics: Anesthesia; Animals; Blood Glucose; Brain; Carbon Isotopes; gamma-Aminobutyric Acid; Glutamic Acid; | 2015 |
Gabapentin as an adjuvant for postoperative pain management in dogs undergoing mastectomy.
Topics: Adjuvants, Anesthesia; Amines; Analgesics; Analgesics, Opioid; Anesthesia; Animals; Cyclohexanecarbo | 2015 |
Hypothalamic feedforward inhibition of thalamocortical network controls arousal and consciousness.
Topics: Anesthesia; Animals; Arousal; Behavior, Animal; Cerebral Cortex; Consciousness; Delta Rhythm; Female | 2016 |
Acute anal stretch inhibits NMDA-dependent pelvic-urethra reflex potentiation via spinal GABAergic inhibition in anesthetized rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Anal Canal; An | 2008 |
Gamma-aminobutyric acid-mediated neurotransmission in the pontine reticular formation modulates hypnosis, immobility, and breathing during isoflurane anesthesia.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cats; gamma-Aminobutyric Acid; Immobility Response, To | 2008 |
Cortical inhibition during burst suppression induced with isoflurane anesthesia.
Topics: Amino Acid Transport System X-AG; Anesthesia; Anesthetics; Animals; Cats; Central Nervous System Age | 2009 |
Gabapentin suppresses cortical spreading depression susceptibility.
Topics: Amines; Anesthesia; Animals; Calcium Channel Blockers; Calcium Channels, N-Type; Cortical Spreading | 2010 |
Pharmacokinetics of gabapentin in cats.
Topics: Administration, Oral; Amines; Anesthesia; Animals; Anticonvulsants; Cats; Cyclohexanecarboxylic Acid | 2010 |
Encoding of the cough reflex in anesthetized guinea pigs.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthesia; Animals; Biphenyl Compounds; Citr | 2011 |
The glutaminergic, GABAergic, dopaminergic but not cholinergic neurons are susceptible to anaesthesia-induced cell death in the rat developing brain.
Topics: Acetylcholine; Anesthesia; Anesthetics, Combined; Animals; Apoptosis; Brain; CA1 Region, Hippocampal | 2011 |
Rats exposed to isoflurane in utero during early gestation are behaviorally abnormal as adults.
Topics: Anesthesia; Anesthetics, Inhalation; Animals; Anxiety; Behavior, Animal; Blood Pressure; Body Weight | 2011 |
Cortical substrate oxidation during hyperketonemia in the fasted anesthetized rat in vivo.
Topics: Algorithms; Amino Acids; Anesthesia; Animals; Aspartic Acid; Astrocytes; Cerebral Cortex; Citric Aci | 2011 |
GABAA receptors involved in sleep and anaesthesia: β1- versus β3-containing assemblies.
Topics: Action Potentials; Anesthesia; Animals; Electrophysiological Phenomena; GABA-A Receptor Agonists; ga | 2012 |
Rat brain slices oxidize glucose at high rates: a (13)C NMR study.
Topics: Acetates; Anesthesia; Anesthetics; Animals; Aspartic Acid; Brain; Carbon Isotopes; gamma-Aminobutyri | 2011 |
Effects of anesthetic regimes on inflammatory responses in a rat model of acute lung injury.
Topics: Acute Lung Injury; Analysis of Variance; Anesthesia; Anesthetics, Dissociative; Anesthetics, General | 2012 |
Neuroscience: Sleep to oblivion.
Topics: Anesthesia; Anesthetics; Animals; gamma-Aminobutyric Acid; Humans; Hypothalamus; Isoflurane; Mice; S | 2012 |
Modulation of spinal nociception by GluR5 kainate receptor ligands in acute and hyperalgesic states and the role of gabaergic mechanisms.
Topics: Anesthesia; Animals; Behavior, Animal; Bicuculline; Electric Stimulation; Electrophysiology; Female; | 2002 |
Neurobiology: Interneurons take charge.
Topics: Action Potentials; Anesthesia; Animals; Consciousness; gamma-Aminobutyric Acid; Hippocampus; Interne | 2003 |
Brain-state- and cell-type-specific firing of hippocampal interneurons in vivo.
Topics: Action Potentials; Anesthesia; Animals; Atropine; Axons; Consciousness; Electrophysiology; gamma-Ami | 2003 |
The difference between sleep and anaesthesia is in the intracellular signal: propofol and GABA use different subtypes of the GABA(A) receptor beta subunit and vary in their interaction with actin.
Topics: Actins; Anesthesia; Anesthetics, Intravenous; Animals; Blotting, Western; Cell Membrane; Cells, Cult | 2003 |
Neuronal activity in the substantia nigra in the anaesthetized rat has fractal characteristics. Evidence for firing-code patterns in the basal ganglia.
Topics: Anesthesia; Animals; Basal Ganglia; Dopamine; Electrophysiology; Fractals; gamma-Aminobutyric Acid; | 2003 |
EEG-arousal by gamma-aminobutyric acid (GABA) in the rabbit under anesthesia, cyanpoisoning or asphyxia.
Topics: Anesthesia; Anesthetics; Animals; Arousal; Asphyxia; Butyrates; Cyanides; Electroencephalography; ga | 1959 |
THE ACTION OF SODIUM 4-HYDROXYBUTYRATE ON SPINAL REFLEXES.
Topics: Aminobutyrates; Anesthesia; Anesthesia, Local; Anesthesiology; Animals; Blood Pressure Determination | 1964 |
A NEUROPHARMACOLOGICAL STUDY OF GAMMA-AMINOBUTYRIC ACID (GABA).
Topics: Aminobutyrates; Anesthesia; Anesthesia, Intravenous; Behavior, Animal; Brain Chemistry; Cats; Chlorp | 1964 |
Angelman syndrome as a rare anaesthetic problem.
Topics: Anesthesia; Angelman Syndrome; Child; gamma-Aminobutyric Acid; Humans; Male | 2004 |
Cold-induced thermogenesis mediated by GABA in the preoptic area of anesthetized rats.
Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Bicuculline; Body Temperature Regulation; Cold Tem | 2004 |
Intracuneate mechanisms underlying primary afferent cutaneous processing in anaesthetized cats.
Topics: Action Potentials; Afferent Pathways; Anesthesia; Animals; Bicuculline; Cats; Dose-Response Relation | 2004 |
The role of gamma-aminobutyric acid and glutamate for hypoxic ventilatory response in anesthetized rabbits.
Topics: Adjuvants, Anesthesia; Anesthesia; Animals; Aorta; Carotid Arteries; Dizocilpine Maleate; Excitatory | 2004 |
Cholinergic regulation of the posterior medial thalamic nucleus.
Topics: Adjuvants, Anesthesia; Anesthesia; Animals; Carbachol; Data Interpretation, Statistical; Electric St | 2006 |
Neuronal excitability in the periaqueductal grey matter during the estrous cycle in female Wistar rats.
Topics: Anesthesia; Animals; Bicuculline; Biotin; Blood Pressure; Electrophysiology; Estrous Cycle; Female; | 2007 |
Acute unilateral ureteral distension inhibits glutamate-dependent spinal pelvic-urethra reflex potentiation via GABAergic neurotransmission in anesthetized rats.
Topics: Action Potentials; Afferent Pathways; Anesthesia; Animals; Bicuculline; Electromyography; Excitatory | 2007 |
Mesopontine tegmental anesthesia area projects independently to the rostromedial medulla and to the spinal cord.
Topics: Anesthesia; Anesthetics, Intravenous; Animals; Biomarkers; Chloral Hydrate; Cholera Toxin; Data Inte | 2007 |
Central hypotensive effect of gamma-aminobutyric acid in anaesthetized dogs.
Topics: Anesthesia; Animals; Blood Pressure; Brain; Cocaine; Depression, Chemical; Dogs; Epinephrine; Female | 1980 |
Effects of peripherally administered GABA and other amino acids on cardiopulmonary responses in anesthetized rats and dogs.
Topics: Amino Acids; Anesthesia; Animals; Atropine; Diphenhydramine; Dogs; Female; gamma-Aminobutyric Acid; | 1982 |
Regional rat brain benzodiazepine receptor number and gamma-aminobutyric acid concentration following a convulsion.
Topics: Anesthesia; Animals; Bicuculline; Brain; Electroshock; gamma-Aminobutyric Acid; Male; Nerve Tissue P | 1982 |
Chlordiazepoxide reduces in vivo serotonin release in the basal ganglia of encéphale isolé but not anesthetized cats: evidence for a dorsal raphe site of action.
Topics: Anesthesia; Animals; Basal Ganglia; Benzodiazepinones; Brain Stem; Cats; Chlordiazepoxide; Decerebra | 1983 |
[A modified method of anesthesia without intubation in microsurgical treatment of the larynx].
Topics: Adolescent; Adult; Aged; Anesthesia; Blood Gas Analysis; Blood Pressure; Electrocardiography; Female | 1984 |
[The action of GABA in arrhythmias induced by CaCl2 in the anesthetized rat].
Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Calcium Chloride; Electrocardiography; Female; gamma-Amin | 1984 |
Central cardiovascular action of penicillin in anaesthetized dogs and rats.
Topics: Adrenalectomy; Anesthesia; Animals; Blood Pressure; Clonidine; Dogs; Female; gamma-Aminobutyric Acid | 1983 |
gamma-butyrolactone enhances the activity of GABA in the gastric acid secretion of anesthetized rats.
Topics: 4-Butyrolactone; Anesthesia; Animals; Diazepam; Drug Synergism; Furans; gamma-Aminobutyric Acid; Gas | 1983 |
Changes in gamma-aminobutyric acid-shunt enzymes in regions of rat brain with ketamine anaesthesia.
Topics: 4-Aminobutyrate Transaminase; Aldehyde Oxidoreductases; Anesthesia; Animals; Brain; gamma-Aminobutyr | 1981 |
The release of endogenous GABA and glutamate from the cerebral cortex in the rat.
Topics: Amino Acids; Amphetamine; Anesthesia; Animals; Cerebral Cortex; Electroencephalography; gamma-Aminob | 1981 |
Inhibitory amino acids and periodic discharges of respiratory neurons in the medulla of the cat.
Topics: Amino Acids; Anesthesia; Animals; Cats; gamma-Aminobutyric Acid; Glycine; Medulla Oblongata; Neurons | 1981 |
Effect of anesthesia and surgical stress on prolactin levels in pregnancy.
Topics: Anesthesia; Estrogens; Female; gamma-Aminobutyric Acid; Humans; Pregnancy; Prolactin; Stress, Physio | 1981 |
Interaction between phencyclidine (PCP) and GABA-ergic drugs: clinical implications.
Topics: Aminooxyacetic Acid; Anesthesia; Animals; Baclofen; Dextroamphetamine; Diazepam; Drug Interactions; | 1980 |
Cardiovascular effects of intracerebroventricular GABA, glycine and muscimol in the rat.
Topics: Anesthesia; Animals; Dopamine; gamma-Aminobutyric Acid; Glycine; Hemodynamics; Injections, Intravent | 1980 |
The release of GABA and glutamate from the cerebral cortex is an index of the activity of underlying aminoacidergic neurons.
Topics: Amino Acids; Aminooxyacetic Acid; Anesthesia; Animals; Brain Chemistry; Cerebral Cortex; gamma-Amino | 1981 |
Systemic phencyclidine administration is associated with increased dopamine, GABA, and 5-HIAA levels in the dorsolateral striatum of conscious rats: an in vivo microdialysis study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Anesthesia; Animals; Aspartic Acid; Consciousness; Corpus Striatum; | 1994 |
Molecular determinants of general anesthetic action: role of GABAA receptor structure.
Topics: Anesthesia; Anesthetics; Animals; Chloride Channels; Diazepam; Drug Synergism; Electric Conductivity | 1993 |
Evidence for involvement of amino acid neurotransmitters in anesthesia and naloxone induced reversal of respiratory paralysis.
Topics: Anesthesia; Anesthetics; Animals; Brain; Brain Stem; Cerebral Cortex; Female; gamma-Aminobutyric Aci | 1994 |
[The effect of anesthesia on acute experimental poisoning of animals by antio, an organophosphorus compound].
Topics: Anesthesia; Animals; Carbon Dioxide; Cats; Drug Synergism; Female; gamma-Aminobutyric Acid; Heart Ra | 1994 |
N-methyl-D-aspartic acid differentially regulates extracellular dopamine, GABA, and glutamate levels in the dorsolateral neostriatum of the halothane-anesthetized rat: an in vivo microdialysis study.
Topics: Anesthesia; Animals; Corpus Striatum; Dialysis; Dopamine; Extracellular Space; gamma-Aminobutyric Ac | 1993 |
Ouabain cardiotoxicity is enhanced by GABA in anesthetized rats.
Topics: Anesthesia; Animals; Blood Pressure; Drug Synergism; gamma-Aminobutyric Acid; Heart; Heart Arrest; H | 1993 |
Sleeping time after phenobarbital treatment and the brain levels of gamma-aminobutyric acid and phenobarbital at the regaining of righting response point in ethionine-induced liver-disordered mice.
Topics: Anesthesia; Anesthesia Recovery Period; Animals; Brain Chemistry; Carcinogens; Chemical and Drug Ind | 1996 |
Hypotensive and hypertensive effects of catecholamines intrathecally injected in anesthetized rats.
Topics: Adrenergic Agonists; Adrenergic Antagonists; Anesthesia; Animals; Blood Pressure; Catecholamines; Cl | 1996 |
Immunocytochemical localization of GABA immunoreactivity in dentate granule cells of normal and kindled rats.
Topics: Anesthesia; Animals; Antibodies, Monoclonal; Antibody Specificity; Dentate Gyrus; Epilepsy; Female; | 1996 |
Potentiation of GABA-induced Cl- current by a series of n-alcohols disappears at a cutoff point of a longer-chain n-alcohol in rat dorsal root ganglion neurons.
Topics: Alcohols; Anesthesia; Animals; Chloride Channel Agonists; Chloride Channels; GABA-A Receptor Agonist | 1996 |
Comparison of responses of spontaneously active cells in the cerebellar Purkinje layer to parallel fibre stimulation in slice preparations and urethane-anaesthetised rats: effects of benzodiazepine receptor ligands.
Topics: Action Potentials; Anesthesia; Anesthetics, Intravenous; Animals; Azepines; Benzodiazepines; Electri | 1998 |
Supraspinal inhibition of nociceptive dorsal horn neurones in the anaesthetized rat: tonic or dynamic?
Topics: Anesthesia; Anesthetics, Local; Animals; Efferent Pathways; Electromyography; Electrophysiology; Evo | 1998 |
GABA may function tonically via GABA(A) receptors to inhibit hypotension and bradycardia by L-DOPA microinjected into depressor sites of the nucleus tractus solitarii in anesthetized rats.
Topics: Anesthesia; Animals; Bicuculline; Binding, Competitive; Bradycardia; Dopamine Agents; Dose-Response | 1999 |
The evidence for tonic GABAergic regulation of basal L-DOPA release via activation of inhibitory GABA(A) receptors in the nucleus tractus solitarii of anesthetized rats.
Topics: Anesthesia; Animals; Bicuculline; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A | 1999 |
Extracellular single-unit recordings of piriform cortex neurons in rats: influence of different types of anesthesia and characterization of neurons by pharmacological manipulation of serotonin receptors.
Topics: Action Potentials; Anesthesia; Anesthetics, Intravenous; Animals; Female; Fluorobenzenes; Gallamine | 1999 |
Effects of noradrenaline on frequency tuning of auditory cortex neurons during wakefulness and slow-wave sleep.
Topics: Acoustic Stimulation; Anesthesia; Animals; Arousal; Auditory Cortex; Evoked Potentials; gamma-Aminob | 1999 |
Adaptive responses of gamma-aminobutyric acid neurons in the ventral tegmental area to chronic ethanol.
Topics: Adaptation, Physiological; Administration, Inhalation; Anesthesia; Animals; Central Nervous System D | 1999 |
On-line derivatization for continuous and automatic monitoring of brain extracellular glutamate levels in anesthetized rats: a microdialysis study.
Topics: Anesthesia; Animals; Aspartic Acid; Autoanalysis; Brain Chemistry; Cerebral Cortex; Chromatography, | 1999 |
Single-unit and polygraphic recordings associated with systemic or local pharmacology: a multi-purpose stereotaxic approach for the awake, anaesthetic-free, and head-restrained rat.
Topics: Action Potentials; Anesthesia; Animals; Arousal; Conditioning, Psychological; Electroencephalography | 2000 |
Antinociception and (R,S)-alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid antagonism by gabapentin in the rat spinal cord in vivo.
Topics: Acetates; Amines; Analgesics; Anesthesia; Animals; Bicuculline; Cyclohexanecarboxylic Acids; Dose-Re | 2000 |
GABA-level increasing and anticonvulsant effects of three different GABA uptake inhibitors.
Topics: Acoustic Stimulation; Anesthesia; Animals; Anisoles; Anticonvulsants; Carbazoles; Chromatography, Hi | 2000 |
Effects of nucleus prepositus hypoglossi lesions on visual climbing fiber activity in the rabbit flocculus.
Topics: Action Potentials; Anesthesia; Animals; Electrophysiology; Eye Movements; gamma-Aminobutyric Acid; M | 2000 |
Response modulations by static texture surround in area V1 of the macaque monkey do not depend on feedback connections from V2.
Topics: Anesthesia; Animals; Electroencephalography; Feedback; gamma-Aminobutyric Acid; Macaca fascicularis; | 2001 |
Female gastrin-releasing peptide receptor (GRP-R)-deficient mice exhibit altered social preference for male conspecifics: implications for GRP/GRP-R modulation of GABAergic function.
Topics: Anesthesia; Animals; Bicuculline; Brain Chemistry; Diazepam; Exploratory Behavior; Feeding Behavior; | 2001 |
GABA(B) presynaptic inhibition has an in vivo time constant sufficiently rapid to allow modulation at theta frequency.
Topics: Anesthesia; Animals; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Male; Neural Inhibition | 2002 |
A pharmacological study of the spontaneous convulsive activity induced by 1,2-dihydroxybenzene (catechol) in the anaesthetized mouse.
Topics: Acetylcholine; Anesthesia; Animals; Atropine; Catechols; Female; gamma-Aminobutyric Acid; Male; Mice | 1977 |
On the mode of action of diazepam on brain catecholamine metabolism.
Topics: 4-Butyrolactone; 5-Hydroxytryptophan; Anesthesia; Animals; Brain; Catecholamines; Diazepam; Dihydrox | 1978 |
Ketamine-induced rotation: interaction with GABA-transaminase inhibitors and picrotoxin.
Topics: 4-Aminobutyrate Transaminase; Anesthesia; Animals; Behavior; Drug Interactions; gamma-Aminobutyric A | 1979 |
Involvement of central GABA receptors in the regulation of blood pressure and heart rate of anesthetized cats.
Topics: Aminobutyrates; Anesthesia; Animals; Blood Pressure; Cats; gamma-Aminobutyric Acid; Glycine; Heart R | 1977 |
Anaesthesia-like condition produced by GABA in cats [proceedings].
Topics: Aminobutyrates; Anesthesia; Animals; Cats; Chickens; Cisterna Magna; gamma-Aminobutyric Acid; Inject | 1977 |
Differential action of (-)-baclofen on the primary afferent depolarization produced by segmental and descending inputs.
Topics: Anesthesia; Animals; Baclofen; Cats; Electric Stimulation; gamma-Aminobutyric Acid; Interneurons; Ne | 1992 |
GABA-mediated inhibition in rostral ventromedial medulla: role in nociceptive modulation in the lightly anesthetized rat.
Topics: Analgesics; Anesthesia; Animals; Bicuculline; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; | 1991 |
Iontophoretic study of medial septal neurons in the unanesthetized rat.
Topics: Anesthesia; Animals; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Iontophoresis; Male; Neuron | 1991 |
In vivo release of newly synthesized [3H]GABA in the substantia nigra of the rat: relative contribution of GABA striato-pallido-nigral afferents and nigral GABA neurons.
Topics: Anesthesia; Animals; Bicuculline; Calcium; Corpus Striatum; gamma-Aminobutyric Acid; Globus Pallidus | 1991 |
Gastric hyperacidity and mucosal damage caused by hypothermia correlate with increase in GABA concentrations of the rat brain.
Topics: Aminooxyacetic Acid; Anesthesia; Animals; Brain Chemistry; Cold Temperature; gamma-Aminobutyric Acid | 1991 |
Central GABAA excitatory and GABAB inhibitory receptors regulate gastric acid secretion in rats.
Topics: Anesthesia; Animals; Baclofen; Bicuculline; Central Nervous System; Dose-Response Relationship, Drug | 1990 |
GABA(B)-related activity involved in synaptic processing of somatosensory information in S1 cortex of the anaesthetized cat.
Topics: Anesthesia; Animals; Baclofen; Bicuculline; Cats; Electric Stimulation; Electrodes; Female; gamma-Am | 1990 |
An in vivo microdialysis characterization of extracellular dopamine and GABA in dorsolateral striatum of awake freely moving and halothane anaesthetised rats.
Topics: Anesthesia; Animals; Calcium; Corpus Striatum; Dialysis; Dopamine; gamma-Aminobutyric Acid; Halothan | 1990 |
Effects of GABA antagonists and structural GABA analogues on baclofen stimulated gastric acid secretion in the rat.
Topics: Amino Acids; Anesthesia; Animals; Baclofen; Bethanechol Compounds; Bicuculline; GABA Antagonists; ga | 1990 |
Direct evidence indicating that a GABA-mimetic stimulates acid secretion through central mechanisms.
Topics: Anesthesia; Animals; Baclofen; Brain; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Gas | 1990 |
Modification of evoked hippocampal dentate inhibition by diazepam and three antagonists in urethane-anesthetized rats.
Topics: Anesthesia; Animals; Diazepam; Evoked Potentials; Flumazenil; gamma-Aminobutyric Acid; Hippocampus; | 1989 |
Fluidization of brain membranes by A2C does not produce anesthesia and does not augment muscimol-stimulated 36Cl- influx.
Topics: Anesthesia; Animals; Benzyl Alcohols; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Co | 1989 |
The effect of peripherally administered GABA on noradrenaline-induced reflex vagal bradycardia in urethane anaesthetized rats.
Topics: Anesthesia; Animals; Drug Interactions; Electric Stimulation; gamma-Aminobutyric Acid; Heart Rate; H | 1985 |
In vivo evidence for acetylcholine control of serotonin release in the cat caudate nucleus: influence of halothane anaesthesia.
Topics: Acetylcholine; Anesthesia; Animals; Bicuculline; Cats; Caudate Nucleus; Decerebrate State; Female; g | 1988 |
Possible involvement of the central GABAergic system in pentobarbital-stimulated gastric acid secretion in the perfused rat stomach preparation.
Topics: 3-Mercaptopropionic Acid; Anesthesia; Animals; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Gastr | 1988 |
[Effect of gamma-aminobutyric acid on cardiac inotropism in the anesthetized guinea pig].
Topics: Adrenalectomy; Anesthesia; Animals; Baclofen; Barbital; Blood Pressure; GABA Antagonists; gamma-Amin | 1987 |
[Presynaptic inhibition--an intra-organ mechanism of the regulation of heart afferents].
Topics: Afferent Pathways; Anesthesia; Animals; Cats; Electric Stimulation; Evoked Potentials; gamma-Aminobu | 1986 |
Differences in cardiovascular responses to peripherally administered GABA as influenced by basal conditions and type of anaesthesia.
Topics: Adrenal Medulla; Adrenalectomy; Anesthesia; Animals; Barbital; Bicuculline; Blood Pressure; Catechol | 1986 |
[Change in the activity of a cell-free protein-synthesizing system with different functional states of the central nervous system].
Topics: Anesthesia; Animals; Brain; Cell-Free System; Chlorpromazine; gamma-Aminobutyric Acid; Hexobarbital; | 1972 |