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gamma-aminobutyric acid and Amphetamine-Related Disorders

gamma-aminobutyric acid has been researched along with Amphetamine-Related Disorders in 10 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Amphetamine-Related Disorders: Disorders related or resulting from use of amphetamines.

Research Excerpts

ExcerptRelevanceReference
"Methamphetamine (Meth) withdrawal elicits anxiety, which is a public health concern with limited therapeutic options."8.31Gegen-Qinlian decoction-A traditional Chinese medicine formula-Alleviates methamphetamine withdrawal induced anxiety by targeting GABAergic interneuron-pyramidal neuron pathway in mPFC. ( Du, D; Fan, Y; Ge, F; Guan, X; Lu, X; Pan, W; Peng, Y; Song, H; Xu, X; Yang, X, 2023)
" Inhibitory gamma-aminobutyric acid (GABA) and excitatory N-methyl-D-aspartate (NMDA) systems play a role in the effect of stimulants in the genesis of epileptic seizures."7.76Effect of cross-fostering on seizures in adult male offspring of methamphetamine-treated rat mothers. ( Bernásková, K; Hrubá, L; Matejovská, I; Rokyta, R; Slamberová, R, 2010)
"Methamphetamine (Meth) withdrawal elicits anxiety, which is a public health concern with limited therapeutic options."4.31Gegen-Qinlian decoction-A traditional Chinese medicine formula-Alleviates methamphetamine withdrawal induced anxiety by targeting GABAergic interneuron-pyramidal neuron pathway in mPFC. ( Du, D; Fan, Y; Ge, F; Guan, X; Lu, X; Pan, W; Peng, Y; Song, H; Xu, X; Yang, X, 2023)
" Inhibitory gamma-aminobutyric acid (GABA) and excitatory N-methyl-D-aspartate (NMDA) systems play a role in the effect of stimulants in the genesis of epileptic seizures."3.76Effect of cross-fostering on seizures in adult male offspring of methamphetamine-treated rat mothers. ( Bernásková, K; Hrubá, L; Matejovská, I; Rokyta, R; Slamberová, R, 2010)
"Patients seeking treatment for methylamphetamine dependence must cope with drug cravings as they engage in psychosocial treatments."2.76A controlled trial of flumazenil and gabapentin for initial treatment of methylamphetamine dependence. ( Baron, M; Hanselka, LL; Urschel, HC, 2011)
"Problematic compounds may cause seizures either acutely or on withdrawal: Their use may reduce effectiveness of antiepileptic drugs, or may simply promote and enhance chaotic lifestyles."2.48Alcohol and drugs in epilepsy: pathophysiology, presentation, possibilities, and prevention. ( Borland, W; Leach, JP; Mohanraj, R, 2012)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (40.00)29.6817
2010's4 (40.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Song, H1
Lu, X1
Du, D1
Peng, Y1
Pan, W1
Xu, X1
Fan, Y1
Yang, X1
Ge, F1
Guan, X1
Su, H1
Chen, T1
Zhong, N1
Jiang, H1
Du, J1
Xiao, K1
Xu, D1
Song, W1
Zhao, M1
Urschel, HC1
Hanselka, LL1
Baron, M1
Slamberová, R1
Hrubá, L1
Bernásková, K1
Matejovská, I1
Rokyta, R1
Ling, W1
Shoptaw, S1
Hillhouse, M1
Bholat, MA1
Charuvastra, C1
Heinzerling, K1
Chim, D1
Annon, J1
Dowling, PT1
Doraimani, G1
Leach, JP1
Mohanraj, R1
Borland, W1
Mohila, CA1
Onn, SP1
Caligiuri, MP1
Buitenhuys, C1
Yin, HS1
Chen, K1
Kalpana, S1
Shih, JC1
Cancela, LM1
Basso, AM1
Martijena, ID1
Capriles, NR1
Molina, VA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Double-Blind, Placebo Controlled Trial of Prometa Pharmacotherapy for the Treatment of Methamphetamine Abuse[NCT00260481]Phase 2/Phase 3120 participants (Actual)Interventional2006-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for gamma-aminobutyric acid and Amphetamine-Related Disorders

ArticleYear
Alcohol and drugs in epilepsy: pathophysiology, presentation, possibilities, and prevention.
    Epilepsia, 2012, Volume: 53 Suppl 4

    Topics: Alcohol Drinking; Alcohol Withdrawal Seizures; Alcoholism; Amphetamine-Related Disorders; Benzodiaze

2012
Do preclinical findings of methamphetamine-induced motor abnormalities translate to an observable clinical phenotype?
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2005, Volume: 30, Issue:12

    Topics: Amphetamine-Related Disorders; Animals; Brain Chemistry; Central Nervous System Stimulants; Dopamine

2005

Trials

2 trials available for gamma-aminobutyric acid and Amphetamine-Related Disorders

ArticleYear
A controlled trial of flumazenil and gabapentin for initial treatment of methylamphetamine dependence.
    Journal of psychopharmacology (Oxford, England), 2011, Volume: 25, Issue:2

    Topics: Adolescent; Adult; Amines; Amphetamine-Related Disorders; Anticonvulsants; Behavior, Addictive; Cycl

2011
Double-blind placebo-controlled evaluation of the PROMETA™ protocol for methamphetamine dependence.
    Addiction (Abingdon, England), 2012, Volume: 107, Issue:2

    Topics: Adult; Amines; Amphetamine-Related Disorders; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug

2012

Other Studies

6 other studies available for gamma-aminobutyric acid and Amphetamine-Related Disorders

ArticleYear
Gegen-Qinlian decoction-A traditional Chinese medicine formula-Alleviates methamphetamine withdrawal induced anxiety by targeting GABAergic interneuron-pyramidal neuron pathway in mPFC.
    Addiction biology, 2023, Volume: 28, Issue:9

    Topics: Amphetamine-Related Disorders; Animals; Anxiety; gamma-Aminobutyric Acid; Interneurons; Medicine, Ch

2023
Decreased GABA concentrations in left prefrontal cortex of methamphetamine dependent patients: A proton magnetic resonance spectroscopy study.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2020, Volume: 71

    Topics: Adult; Amphetamine-Related Disorders; Female; gamma-Aminobutyric Acid; Humans; Male; Methamphetamine

2020
Effect of cross-fostering on seizures in adult male offspring of methamphetamine-treated rat mothers.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2010, Volume: 28, Issue:6

    Topics: Amphetamine-Related Disorders; Animals; Female; gamma-Aminobutyric Acid; Male; Maternal Behavior; Me

2010
Increases in the density of parvalbumin-immunoreactive neurons in anterior cingulate cortex of amphetamine-withdrawn rats: evidence for corticotropin-releasing factor in sustained elevation.
    Cerebral cortex (New York, N.Y. : 1991), 2005, Volume: 15, Issue:3

    Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Calbindin 1; Calbindin 2; Calbindins; Calcium-B

2005
Differential effects of chronic amphetamine and baclofen administration on cAMP levels and phosphorylation of CREB in distinct brain regions of wild type and monoamine oxidase B-deficient mice.
    Synapse (New York, N.Y.), 2006, Dec-15, Volume: 60, Issue:8

    Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Baclofen; Biogenic Monoamines; Brain; Central N

2006
A dopaminergic mechanism is involved in the 'anxiogenic-like' response induced by chronic amphetamine treatment: a behavioral and neurochemical study.
    Brain research, 2001, Aug-03, Volume: 909, Issue:1-2

    Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Anxiety; Behavior, Animal; Benzazepines; Brain;

2001