gamma-aminobutyric acid has been researched along with Amnesia in 21 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Amnesia: Pathologic partial or complete loss of the ability to recall past experiences (AMNESIA, RETROGRADE) or to form new memories (AMNESIA, ANTEROGRADE). This condition may be of organic or psychologic origin. Organic forms of amnesia are usually associated with dysfunction of the DIENCEPHALON or HIPPOCAMPUS. (From Adams et al., Principles of Neurology, 6th ed, pp426-7)
| Excerpt | Relevance | Reference |
|---|---|---|
| "An experimental model of amnesia induced by cerebral ischemia after one-trial passive avoidance learning was established to test the effects of a novel compound, 6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone (idebenone, CV-2619), and some commonly used drugs in rats." | 7.67 | Beneficial effect of idebenone (CV-2619) on cerebral ischemia-induced amnesia in rats. ( Nagaoka, A; Nagawa, Y; Take, Y; Yamazaki, N, 1984) |
| "The amnesia was estimated by the response latency for a rat to step from a light safety compartment to a dark compartment in which a foot-shock was given." | 5.27 | Beneficial effect of idebenone (CV-2619) on cerebral ischemia-induced amnesia in rats. ( Nagaoka, A; Nagawa, Y; Take, Y; Yamazaki, N, 1984) |
| "GABA analogs containing phenyl (phenibut) or para-chlorophenyl (baclofen) substituents demonstrated nootropic activity in a dose of 20 mg/kg: they improved passive avoidance conditioning, decelerated its natural extinction, and exerted antiamnestic effect on the models of amnesia provoked by scopolamine or electroshock." | 3.83 | Comparison of Nootropic and Neuroprotective Features of Aryl-Substituted Analogs of Gamma-Aminobutyric Acid. ( Bagmetova, VV; Berestovitskaya, VM; Borodkina, LE; Tyurenkov, IN; Vasil'eva, OS, 2016) |
| " In Wernicke-Korsakoff's syndrome (WKS) and the animal model of the disorder, pyrithiamine-induced thiamine deficiency (PTD), there is both diencephalic damage and basal forebrain cell loss that could contribute to the amnesic state." | 3.75 | The role of cholinergic and GABAergic medial septal/diagonal band cell populations in the emergence of diencephalic amnesia. ( Roland, JJ; Savage, LM, 2009) |
| " Etomidate is a nonbarbiturate, intravenous anesthetic that selectively modulates GABA(A) receptors and produces amnesia at low doses in vivo." | 3.75 | Amnestic concentrations of etomidate modulate GABAA,slow synaptic inhibition in hippocampus. ( Dai, S; Pearce, RA; Perouansky, M, 2009) |
| "We studied the effects of naftidrofuryl oxalate on scopolamine- and basal forebrain (BF) lesion-induced amnesia using passive avoidance and multiple T-maze tasks, in comparison with Ca-hopantenate and physostigmine in rats." | 3.68 | Naftidrofuryl oxalate, nootropic effects on the scopolamine- and the basal forebrain lesion-induced amnesia in rats. ( Kameyama, T; Nabeshima, T; Ogawa, S, 1991) |
| "The effects of N-(2,6-dimethyl-phenyl)-2-(2-oxo-1-pyrrolidinyl)acetamide (DM-9384), a cyclic derivative of GABA, were investigated and compared with those of aniracetam in an animal model of amnesia, using a passive avoidance task with animals that have GABAergic neuronal dysfunctions." | 3.68 | Effects of DM-9384 in a model of amnesia based on animals with GABAergic neuronal dysfunctions. ( Itoh, J; Kameyama, T; Nabeshima, T; Noda, Y; Tohyama, K, 1990) |
| " Cetyl GABA, sodium and lithium hydroxybutyrates and phenibut were shown to be able to decrease the retrograde amnesia caused by electroshock in passive avoidance performance." | 3.67 | [Nootropic properties of gamma-aminobutyric acid derivatives]. ( Ostrovskaia, RU; Trofimov, SS, 1984) |
| "An experimental model of amnesia induced by cerebral ischemia after one-trial passive avoidance learning was established to test the effects of a novel compound, 6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone (idebenone, CV-2619), and some commonly used drugs in rats." | 3.67 | Beneficial effect of idebenone (CV-2619) on cerebral ischemia-induced amnesia in rats. ( Nagaoka, A; Nagawa, Y; Take, Y; Yamazaki, N, 1984) |
| "Infantile amnesia is a ubiquitous phenomenon, but its neural bases remain largely unknown." | 1.33 | Recovery of fear memories in rats: role of gamma-amino butyric acid (GABA) in infantile amnesia. ( Kim, JH; McNally, GP; Richardson, R, 2006) |
| "The amnesia was estimated by the response latency for a rat to step from a light safety compartment to a dark compartment in which a foot-shock was given." | 1.27 | Beneficial effect of idebenone (CV-2619) on cerebral ischemia-induced amnesia in rats. ( Nagaoka, A; Nagawa, Y; Take, Y; Yamazaki, N, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (28.57) | 18.7374 |
| 1990's | 3 (14.29) | 18.2507 |
| 2000's | 7 (33.33) | 29.6817 |
| 2010's | 2 (9.52) | 24.3611 |
| 2020's | 3 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Puig-Bosch, X | 1 |
| Bieletzki, S | 1 |
| Zeilhofer, HU | 1 |
| Rudolph, U | 1 |
| Antkowiak, B | 1 |
| Rammes, G | 1 |
| Forman, SA | 1 |
| Nkwingwa, BK | 1 |
| Wado, EK | 1 |
| Foyet, HS | 1 |
| Bouvourne, P | 1 |
| Jugha, VT | 1 |
| Mambou, AHMY | 1 |
| Bila, RB | 1 |
| Taiwe, GS | 1 |
| Tyurenkov, IN | 1 |
| Borodkina, LE | 1 |
| Bagmetova, VV | 1 |
| Berestovitskaya, VM | 1 |
| Vasil'eva, OS | 1 |
| Roland, JJ | 1 |
| Savage, LM | 1 |
| Garden, DL | 1 |
| Massey, PV | 1 |
| Caruana, DA | 1 |
| Johnson, B | 1 |
| Warburton, EC | 1 |
| Aggleton, JP | 1 |
| Bashir, ZI | 1 |
| Dai, S | 1 |
| Perouansky, M | 1 |
| Pearce, RA | 1 |
| Nishikawa, K | 2 |
| Kim, JH | 1 |
| McNally, GP | 1 |
| Richardson, R | 1 |
| Brouillette, J | 1 |
| Young, D | 1 |
| During, MJ | 1 |
| Quirion, R | 1 |
| Ishizeki, J | 1 |
| Kubo, K | 1 |
| Saito, S | 1 |
| Goto, F | 1 |
| Ostrovskaia, RU | 1 |
| Trofimov, SS | 1 |
| Banfi, S | 1 |
| Fonio, W | 1 |
| Allievi, E | 1 |
| Pinza, M | 1 |
| Dorigotti, L | 1 |
| Yamazaki, N | 1 |
| Take, Y | 1 |
| Nagaoka, A | 1 |
| Nagawa, Y | 1 |
| Froestl, W | 1 |
| Mickel, SJ | 1 |
| von Sprecher, G | 1 |
| Diel, PJ | 1 |
| Hall, RG | 1 |
| Maier, L | 1 |
| Strub, D | 1 |
| Melillo, V | 1 |
| Baumann, PA | 1 |
| Bernasconi, R | 1 |
| de-Paris, F | 1 |
| Busnello, JV | 1 |
| Vianna, MR | 1 |
| Salgueiro, JB | 1 |
| Quevedo, J | 1 |
| Izquierdo, I | 1 |
| Kapczinski, F | 1 |
| Clark, EO | 1 |
| Glanzer, M | 1 |
| Turndorf, H | 1 |
| Ogawa, S | 1 |
| Kameyama, T | 3 |
| Nabeshima, T | 3 |
| Noda, Y | 1 |
| Tohyama, K | 1 |
| Itoh, J | 1 |
| Anami, K | 1 |
| Setoguchi, M | 1 |
| Senoh, H | 1 |
| Yoshida, S | 1 |
1 review available for gamma-aminobutyric acid and Amnesia
| Article | Year |
|---|---|
[Balance between glutamatergic excitation and GABAergic inhibition in the brain regulates hypnotic and amnestic actions of general anesthetics, and pain thresholds].
Topics: Amnesia; Anesthetics, General; Animals; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Humans; | 2010 |
20 other studies available for gamma-aminobutyric acid and Amnesia
| Article | Year |
|---|---|
Midazolam at Low Nanomolar Concentrations Affects Long-term Potentiation and Synaptic Transmission Predominantly via the α1-γ-Aminobutyric Acid Type A Receptor Subunit in Mice.
Topics: Amnesia; Animals; Female; gamma-Aminobutyric Acid; Long-Term Potentiation; Male; Mice; Midazolam; Re | 2022 |
γ-Aminobutyric Acid Type A Receptor Subtypes and Circuit Connections in Midazolam-induced Amnesia, Sedation, and Hypnosis.
Topics: Amnesia; Conscious Sedation; gamma-Aminobutyric Acid; Humans; Hypnosis; Hypnotics and Sedatives; Mid | 2022 |
Ameliorative effects of Albizia adianthifolia aqueous extract against pentylenetetrazole-induced epilepsy and associated memory loss in mice: Role of GABAergic, antioxidant defense and anti-inflammatory systems.
Topics: Albizzia; Amnesia; Animals; Anti-Inflammatory Agents; Anticonvulsants; Antioxidants; Epilepsy; gamma | 2023 |
Comparison of Nootropic and Neuroprotective Features of Aryl-Substituted Analogs of Gamma-Aminobutyric Acid.
Topics: Amnesia; Animals; Anticonvulsants; Avoidance Learning; Baclofen; Cinnamates; Coma; Electroshock; gam | 2016 |
The role of cholinergic and GABAergic medial septal/diagonal band cell populations in the emergence of diencephalic amnesia.
Topics: Acetylcholine; Amnesia; Animals; Brain; Calbindins; Cell Death; Choline O-Acetyltransferase; Disease | 2009 |
Anterior thalamic lesions stop synaptic plasticity in retrosplenial cortex slices: expanding the pathology of diencephalic amnesia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amnesia; Animals; Anterior Thalamic Nuclei | 2009 |
Amnestic concentrations of etomidate modulate GABAA,slow synaptic inhibition in hippocampus.
Topics: Amnesia; Animals; Electrophysiology; Etomidate; Excitatory Postsynaptic Potentials; GABA Antagonists | 2009 |
Recovery of fear memories in rats: role of gamma-amino butyric acid (GABA) in infantile amnesia.
Topics: Amnesia; Animals; Animals, Newborn; Carbolines; Fear; GABA Agonists; gamma-Aminobutyric Acid; Inject | 2006 |
Hippocampal gene expression profiling reveals the possible involvement of Homer1 and GABA(B) receptors in scopolamine-induced amnesia.
Topics: Amnesia; Animals; Carrier Proteins; Disease Models, Animal; GABA Antagonists; GABA-B Receptor Antago | 2007 |
Amnestic concentrations of sevoflurane inhibit synaptic plasticity of hippocampal CA1 neurons through gamma-aminobutyric acid-mediated mechanisms.
Topics: Amnesia; Animals; gamma-Aminobutyric Acid; Hippocampus; Long-Term Potentiation; Methyl Ethers; Neuro | 2008 |
[Nootropic properties of gamma-aminobutyric acid derivatives].
Topics: Amnesia; Amnesia, Retrograde; Animals; Avoidance Learning; Baclofen; Butyrates; Conditioning, Classi | 1984 |
Cyclic GABA-GABOB analogues. IV. Activity on learning and memory.
Topics: Amnesia; Animals; Chemical Phenomena; Chemistry; Electroshock; gamma-Aminobutyric Acid; Humans; Lear | 1984 |
Beneficial effect of idebenone (CV-2619) on cerebral ischemia-induced amnesia in rats.
Topics: Amnesia; Animals; Arginine Vasopressin; Avoidance Learning; Benzoquinones; Brain Ischemia; Condition | 1984 |
Phosphinic acid analogues of GABA. 2. Selective, orally active GABAB antagonists.
Topics: Administration, Oral; Amnesia; Animals; Cerebral Cortex; GABA-B Receptor Antagonists; gamma-Aminobut | 1995 |
The anticonvulsant compound gabapentin possesses anxiolytic but not amnesic effects in rats.
Topics: Acetates; Amines; Amnesia; Animals; Anti-Anxiety Agents; Anticonvulsants; Avoidance Learning; Cycloh | 2000 |
The pattern of memory loss resulting from intravenously administered diazepam.
Topics: Amnesia; Diazepam; gamma-Aminobutyric Acid; Hippocampus; Humans; Injections, Intravenous; Memory | 1979 |
Naftidrofuryl oxalate, nootropic effects on the scopolamine- and the basal forebrain lesion-induced amnesia in rats.
Topics: Amnesia; Animals; Avoidance Learning; Cerebral Cortex; Choline O-Acetyltransferase; gamma-Aminobutyr | 1991 |
Effects of DM-9384 in a model of amnesia based on animals with GABAergic neuronal dysfunctions.
Topics: Amnesia; Animals; Avoidance Learning; Bicuculline; Central Nervous System Agents; gamma-Aminobutyric | 1990 |
[Pharmacological studies on Y-8894. (VIII). Effects on learning and memory in the radial maze task in mice].
Topics: Amnesia; Animals; Dihydroergotoxine; gamma-Aminobutyric Acid; Learning; Memory; Mice; Morpholines; P | 1988 |
Effects of the novel compound NIK-247 on impairment of passive avoidance response in mice.
Topics: Aminoquinolines; Amnesia; Animals; Avoidance Learning; Choline; Cholinesterase Inhibitors; Cyclohexi | 1988 |