gamma-aminobutyric acid has been researched along with Amentia in 68 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Excerpt | Relevance | Reference |
---|---|---|
"Twelve patients with moderate to severe dementia and severe behavioral disorders were treated with open-label gabapentin (200-1,200 mg/day) for 8 weeks in a prospective case-series design." | 9.09 | Effectiveness of gabapentin for the treatment of behavioral disorders in dementia. ( Herrmann, N; Lanctôt, K; Myszak, M, 2000) |
" Controlled trials in elderly patients with epilepsy demonstrate efficacy and tolerability comparable to gabapentin." | 8.84 | Lamotrigine therapy in elderly patients with epilepsy, bipolar disorder or dementia. ( Nanry, K; Ramsay, E; Sajatovic, M; Thompson, T, 2007) |
"Reports of lamotrigine therapy in elderly patients with epilepsy, bipolar disorder (BD), or dementia were identified by conducting an electronic search of major publication databases." | 8.84 | Lamotrigine therapy in elderly patients with epilepsy, bipolar disorder or dementia. ( Nanry, K; Ramsay, E; Sajatovic, M; Thompson, T, 2007) |
"Review of the available literature suggests lamotrigine is effective and well tolerated in elderly patients with epilepsy and relatively well-tolerated and may be effective in delaying mood relapse, particularly in the depressive pole, in patients with BD." | 8.84 | Lamotrigine therapy in elderly patients with epilepsy, bipolar disorder or dementia. ( Nanry, K; Ramsay, E; Sajatovic, M; Thompson, T, 2007) |
"Our patient, a 77-year-old Czech woman with incipient vascular dementia, received gabapentin 400mg at bedtime for 6 months and showed convincing improvement." | 7.77 | Gabapentin in the treatment of dementia-associated nocturnal agitation. ( Busek, P; Buskova, J; Nevsimalova, S, 2011) |
"In a 24-patient case series from retrospective chart review, the authors examined the use of gabapentin for the treatment of aggressive and agitated behaviors in nursing home patients with a DSM-IV diagnosis of dementia." | 7.70 | A retrospective chart review of gabapentin for the treatment of aggressive and agitated behavior in patients with dementias. ( Hawkins, JW; Peyser, CE; Sheikh, JI; Tinklenberg, JR; Yesavage, JA, 2000) |
"Gabapentin was generally well tolerated in this population." | 6.69 | Effectiveness of gabapentin for the treatment of behavioral disorders in dementia. ( Herrmann, N; Lanctôt, K; Myszak, M, 2000) |
"Gabapentin was very effective in treating nocturnal agitation." | 5.37 | Gabapentin in the treatment of dementia-associated nocturnal agitation. ( Busek, P; Buskova, J; Nevsimalova, S, 2011) |
" According to a predefined scheme for 8 weeks, all patients in the intervention group received individual daily pain treatment with acetaminophen, extended release morphine, buprenorphine transdermal patch, and/or pregabaline." | 5.19 | The response of agitated behavior to pain management in persons with dementia. ( Aarsland, D; Ballard, C; Cohen-Mansfield, J; Husebo, BS; Seifert, R, 2014) |
"Pain medication significantly improved pain in the intervention group, with indications that acetaminophen also improved ADL function." | 5.19 | Impact of a stepwise protocol for treating pain on pain intensity in nursing home patients with dementia: a cluster randomized trial. ( Aarsland, D; Ballard, C; Corbett, A; Husebo, BS; Sandvik, RK; Seifert, R; Selbaek, G, 2014) |
"Twelve patients with moderate to severe dementia and severe behavioral disorders were treated with open-label gabapentin (200-1,200 mg/day) for 8 weeks in a prospective case-series design." | 5.09 | Effectiveness of gabapentin for the treatment of behavioral disorders in dementia. ( Herrmann, N; Lanctôt, K; Myszak, M, 2000) |
" The purpose of this review of the literature is to assess the interest and the limits of anticonvulsant mood stabilizers (carbamazepine, valproic acid, gabapentin, lamotrigine, topiramate, oxcarbazepine) in the treatment of the so-called "noncognitive" symptoms of dementia." | 4.84 | [Anticonvulsant mood stabilizers in the treatment of behavioral and psychological symptoms of dementia (BPSD)]. ( Pinheiro, D, 2008) |
"Among these medications, only carbamazepine demonstrated its efficacy in behavioral and psychological symptoms of dementia (BPSD) in controlled studies, notably that of Tariot et al." | 4.84 | [Anticonvulsant mood stabilizers in the treatment of behavioral and psychological symptoms of dementia (BPSD)]. ( Pinheiro, D, 2008) |
" Controlled trials in elderly patients with epilepsy demonstrate efficacy and tolerability comparable to gabapentin." | 4.84 | Lamotrigine therapy in elderly patients with epilepsy, bipolar disorder or dementia. ( Nanry, K; Ramsay, E; Sajatovic, M; Thompson, T, 2007) |
"Reports of lamotrigine therapy in elderly patients with epilepsy, bipolar disorder (BD), or dementia were identified by conducting an electronic search of major publication databases." | 4.84 | Lamotrigine therapy in elderly patients with epilepsy, bipolar disorder or dementia. ( Nanry, K; Ramsay, E; Sajatovic, M; Thompson, T, 2007) |
"Review of the available literature suggests lamotrigine is effective and well tolerated in elderly patients with epilepsy and relatively well-tolerated and may be effective in delaying mood relapse, particularly in the depressive pole, in patients with BD." | 4.84 | Lamotrigine therapy in elderly patients with epilepsy, bipolar disorder or dementia. ( Nanry, K; Ramsay, E; Sajatovic, M; Thompson, T, 2007) |
"To review and summarize the currently available data on the use of anticonvulsant mood stabilizers (carbamazepine, valproic acid, gabapentin, lamotrigine, topiramate) in the treatment of behavioral and psychological symptoms of dementia (BPSD); to determine whether these medications can be recommended for routine clinical use." | 4.84 | Anticonvulsants for the treatment of behavioral and psychological symptoms of dementia: a literature review. ( Konovalov, S; Muralee, S; Tampi, RR, 2008) |
"Our patient, a 77-year-old Czech woman with incipient vascular dementia, received gabapentin 400mg at bedtime for 6 months and showed convincing improvement." | 3.77 | Gabapentin in the treatment of dementia-associated nocturnal agitation. ( Busek, P; Buskova, J; Nevsimalova, S, 2011) |
"In a 24-patient case series from retrospective chart review, the authors examined the use of gabapentin for the treatment of aggressive and agitated behaviors in nursing home patients with a DSM-IV diagnosis of dementia." | 3.70 | A retrospective chart review of gabapentin for the treatment of aggressive and agitated behavior in patients with dementias. ( Hawkins, JW; Peyser, CE; Sheikh, JI; Tinklenberg, JR; Yesavage, JA, 2000) |
"In addition, restlessness and pacing were sensible to analgesics." | 2.79 | The response of agitated behavior to pain management in persons with dementia. ( Aarsland, D; Ballard, C; Cohen-Mansfield, J; Husebo, BS; Seifert, R, 2014) |
"Pain is frequent and distressing in people with dementia, but no randomized controlled trials have evaluated the effect of analgesic treatment on pain intensity as a key outcome." | 2.79 | Impact of a stepwise protocol for treating pain on pain intensity in nursing home patients with dementia: a cluster randomized trial. ( Aarsland, D; Ballard, C; Corbett, A; Husebo, BS; Sandvik, RK; Seifert, R; Selbaek, G, 2014) |
"Gabapentin was generally well tolerated in this population." | 2.69 | Effectiveness of gabapentin for the treatment of behavioral disorders in dementia. ( Herrmann, N; Lanctôt, K; Myszak, M, 2000) |
"Dementia is a progressive neurodegenerative disorder with cognitive dysfunction, and is often complicated by behavioral and psychological symptoms of dementia (BPSD) including excitement, aggression, and hallucinations." | 2.53 | Neuropharmacological efficacy of the traditional Japanese Kampo medicine yokukansan and its active ingredients. ( Ikarashi, Y; Mizoguchi, K, 2016) |
"Manganese (Mn) is an essential trace element that is required for maintaining proper function and regulation of numerous biochemical and cellular reactions." | 2.49 | Manganese toxicity in the central nervous system: the glutamine/glutamate-γ-aminobutyric acid cycle. ( Aschner, M; Sidoryk-Wegrzynowicz, M, 2013) |
" Despite its essentiality, at excessive levels Mn is toxic to the central nervous system (CNS)." | 2.49 | Manganese toxicity in the central nervous system: the glutamine/glutamate-γ-aminobutyric acid cycle. ( Aschner, M; Sidoryk-Wegrzynowicz, M, 2013) |
"Gabapentin was very effective in treating nocturnal agitation." | 1.37 | Gabapentin in the treatment of dementia-associated nocturnal agitation. ( Busek, P; Buskova, J; Nevsimalova, S, 2011) |
"These observations suggest that in Alzheimer's disease there are no major changes in the extracellular concentrations of these putative amino acid transmitters." | 1.27 | Amino acid release from biopsy samples of temporal neocortex from patients with Alzheimer's disease. ( Bowen, DM; Davison, AN; Neary, D; Sims, NR; Smith, CC, 1983) |
"gamma-Aminobutyric acid (GABA) was measured in CSF as such and following acid hydrolysis by the ion-exchange/fluorometric method." | 1.27 | Free and conjugated GABA in human cerebrospinal fluid: effect of degenerative neurologic diseases and isoniazid. ( Manyam, BV; Tremblay, RD, 1984) |
"In patients with Huntington's disease, on administration of isoniazid at 900 mg/day, along with pyridoxine at 100 mg/day, a 4-fold increase of both free (P less than 0." | 1.27 | Free and conjugated GABA in human cerebrospinal fluid: effect of degenerative neurologic diseases and isoniazid. ( Manyam, BV; Tremblay, RD, 1984) |
"Neuropathologically, Huntington's disease is characterized by a profound reduction in neuronal cells originating in the corpus striatum and globus pallidus." | 1.26 | Cerebrospinal fluid gamma-aminobutyric acid variations in neurological disorders. ( Enna, SJ; Stern, LZ; Wastek, GJ; Yamamura, HI, 1977) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 39 (57.35) | 18.7374 |
1990's | 4 (5.88) | 18.2507 |
2000's | 14 (20.59) | 29.6817 |
2010's | 11 (16.18) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Shalev, D | 1 |
Arbuckle, MR | 1 |
Gilbert, N | 1 |
Husebo, BS | 2 |
Ballard, C | 2 |
Cohen-Mansfield, J | 1 |
Seifert, R | 2 |
Aarsland, D | 2 |
Sandvik, RK | 1 |
Selbaek, G | 1 |
Corbett, A | 1 |
Breivik, H | 1 |
Ikarashi, Y | 1 |
Mizoguchi, K | 1 |
Pinheiro, D | 1 |
Hagino, T | 1 |
Ochiai, S | 1 |
Sato, E | 1 |
Watanabe, Y | 1 |
Senga, S | 1 |
Haro, H | 1 |
Jeong, DU | 1 |
Chang, WS | 1 |
Hwang, YS | 1 |
Lee, D | 1 |
Chang, JW | 1 |
Buskova, J | 1 |
Busek, P | 1 |
Nevsimalova, S | 1 |
Nilsen, LH | 1 |
Rae, C | 1 |
Ittner, LM | 1 |
Götz, J | 1 |
Sonnewald, U | 1 |
Sidoryk-Wegrzynowicz, M | 1 |
Aschner, M | 1 |
FEITELEVICH, J | 1 |
ZIPILIVAN, M | 1 |
Moretti, R | 1 |
Torre, P | 1 |
Antonello, RM | 1 |
Cazzato, G | 1 |
Bava, A | 1 |
Inada, K | 1 |
Ishigooka, J | 1 |
Horvath, J | 1 |
Coeytaux, A | 1 |
Jallon, P | 1 |
Landis, T | 1 |
Temperli, P | 1 |
Burkhard, PR | 1 |
Sajatovic, M | 1 |
Ramsay, E | 1 |
Nanry, K | 1 |
Thompson, T | 1 |
Bhat, R | 1 |
Rockwood, K | 1 |
Konovalov, S | 1 |
Muralee, S | 1 |
Tampi, RR | 1 |
Rueda, N | 1 |
Flórez, J | 1 |
Martínez-Cué, C | 1 |
Talarovicova, A | 1 |
Krskova, L | 1 |
Kiss, A | 1 |
McGeer, EG | 2 |
McGeer, PL | 1 |
Rossor, MN | 4 |
Emson, PC | 1 |
Mountjoy, CQ | 3 |
Roth, M | 3 |
Iversen, LL | 3 |
Smith, CC | 1 |
Bowen, DM | 3 |
Sims, NR | 1 |
Neary, D | 1 |
Davison, AN | 4 |
Davies, P | 2 |
Greenwald, BS | 1 |
Davis, KL | 1 |
Coyle, JT | 1 |
Singer, H | 1 |
McKinney, M | 1 |
Price, D | 1 |
Bareggi, SR | 1 |
Franceschi, M | 1 |
Bonini, L | 1 |
Zecca, L | 1 |
Smirne, S | 1 |
Kuroda, H | 1 |
Barbosa, ER | 1 |
Marchiori, PE | 1 |
Scaff, M | 1 |
de Assis, JL | 1 |
Manyam, BV | 1 |
Tremblay, RD | 1 |
Cross, AJ | 1 |
Crow, TJ | 1 |
Ferrier, IN | 1 |
Johnson, JA | 1 |
Markakis, D | 1 |
Manyam, NV | 1 |
Katz, L | 1 |
Hare, TA | 1 |
Gerber, JC | 1 |
Grossman, MH | 1 |
Zimmer, R | 1 |
Teelken, AW | 1 |
Trieling, WB | 1 |
Weber, W | 1 |
Weihmayr, T | 1 |
Lauter, H | 1 |
Roberts, E | 1 |
Garrett, NJ | 1 |
Johnson, AL | 1 |
Tarbit, I | 1 |
Perry, EK | 1 |
Perry, RH | 1 |
Blessed, G | 1 |
Tomlinson, BE | 1 |
Sheldon, LJ | 1 |
Ancill, RJ | 1 |
Holliday, SG | 1 |
Goldenberg, G | 1 |
Kahaner, K | 1 |
Basavaraju, N | 1 |
Rangu, S | 1 |
Herrmann, N | 1 |
Lanctôt, K | 1 |
Myszak, M | 1 |
Hawkins, JW | 1 |
Tinklenberg, JR | 1 |
Sheikh, JI | 1 |
Peyser, CE | 1 |
Yesavage, JA | 1 |
Lindenmayer, JP | 1 |
Inoue, T | 1 |
Wang, F | 1 |
Moriguchi, A | 1 |
Shirakawa, K | 1 |
Matsuoka, N | 1 |
Goto, T | 1 |
Rossi, P | 1 |
Serrao, M | 1 |
Pozzessere, G | 1 |
Toru, M | 1 |
Spillane, JA | 1 |
Goodhart, MJ | 1 |
White, P | 1 |
Terry, RD | 1 |
Achar, VS | 1 |
Welch, KM | 1 |
Chabi, E | 1 |
Bartosh, K | 1 |
Meyer, JS | 1 |
Enna, SJ | 2 |
Stern, LZ | 1 |
Wastek, GJ | 1 |
Yamamura, HI | 2 |
McNamara, JO | 1 |
Appel, SH | 1 |
Reisine, TD | 1 |
Bird, ED | 1 |
Spokes, E | 1 |
Tosca, P | 1 |
Canevari, L | 1 |
Di Paolo, E | 1 |
Ferrari, R | 1 |
Verzé, S | 1 |
Zerbi, F | 1 |
Dagani, F | 1 |
Reynolds, GP | 1 |
Pearson, SJ | 1 |
Heathfield, KW | 1 |
Kish, SJ | 1 |
Chang, LJ | 1 |
Mirchandani, L | 1 |
Shannak, K | 1 |
Hornykiewicz, O | 1 |
Kanazawa, I | 1 |
Kwak, S | 1 |
Sasaki, H | 1 |
Muramoto, O | 1 |
Mizutani, T | 1 |
Hori, A | 1 |
Nukina, N | 1 |
Pomara, N | 1 |
Deptula, D | 1 |
Galloway, MP | 1 |
LeWitt, PA | 1 |
Stanley, M | 1 |
Jones, EG | 1 |
Mirsky, AF | 1 |
Duncan, CC | 1 |
Myslobodsky, MS | 1 |
Nakahiro, M | 1 |
Mochizuki, D | 1 |
Uchida, S | 1 |
Yoshida, H | 1 |
Otomo, E | 1 |
Noda, S | 1 |
Umezaki, H | 1 |
Yamamoto, K | 1 |
Araki, T | 1 |
Murakami, T | 1 |
Ishii, N | 1 |
Nakamura, S | 1 |
Kameyama, M | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
The Impact of Pain on Behavioural Disturbances in Patients With Moderate and Severe Dementia. A Cluster Randomized Trial[NCT01021696] | Phase 2/Phase 3 | 352 participants (Actual) | Interventional | 2009-11-30 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
18 reviews available for gamma-aminobutyric acid and Amentia
Article | Year |
---|---|
Neuropharmacological efficacy of the traditional Japanese Kampo medicine yokukansan and its active ingredients.
Topics: Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Catecholamines; Dementia; Drugs, Chinese Herbal | 2016 |
[Anticonvulsant mood stabilizers in the treatment of behavioral and psychological symptoms of dementia (BPSD)].
Topics: Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dementia; Fructose; Gabap | 2008 |
Manganese toxicity in the central nervous system: the glutamine/glutamate-γ-aminobutyric acid cycle.
Topics: Central Nervous System; Dementia; Evidence-Based Medicine; gamma-Aminobutyric Acid; Glutamic Acid; G | 2013 |
[Dementia induced by antianxiety drugs].
Topics: Aging; Anti-Anxiety Agents; Benzodiazepines; Chlorides; Dementia; GABA-A Receptor Agonists; gamma-Am | 2004 |
Lamotrigine therapy in elderly patients with epilepsy, bipolar disorder or dementia.
Topics: Aged; Aged, 80 and over; Amines; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; | 2007 |
Anticonvulsants for the treatment of behavioral and psychological symptoms of dementia: a literature review.
Topics: Aggression; Amines; Anticonvulsants; Carbamazepine; Cognition Disorders; Cyclohexanecarboxylic Acids | 2008 |
Some assessments of the amygdala role in suprahypothalamic neuroendocrine regulation: a minireview.
Topics: Alzheimer Disease; Amygdala; Anxiety Disorders; Autistic Disorder; Corticotropin-Releasing Hormone; | 2007 |
Neurotransmitter systems in aging and senile dementia.
Topics: Acetylcholine; Aged; Aging; Animals; Brain; Choline; Clinical Trials as Topic; Dementia; Dopamine; g | 1981 |
An update on the neurochemistry of Alzheimer disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Arecoline; Brain; Choline; Choline O-Acetyltransferase; Cho | 1983 |
Experimental pharmacology of Alzheimer disease.
Topics: Acetylcholine; Adult; Aged; Alzheimer Disease; Dementia; Dopamine; gamma-Aminobutyric Acid; Humans; | 1983 |
Neurotransmitter specific alterations in dementing disorders: insights from animal models.
Topics: Alzheimer Disease; Animals; Brain; Cats; Cerebral Cortex; Cholinergic Fibers; Dementia; Disease Mode | 1984 |
The pathophysiology of agitation.
Topics: Aggression; Behavioral Symptoms; Bipolar Disorder; Dementia; Dopamine; gamma-Aminobutyric Acid; Huma | 2000 |
[Abnormal neurotransmission in neurological diseases (author's transl)].
Topics: Acetylcholine; Animals; Antiparkinson Agents; Corpus Striatum; Dementia; Dopamine; Female; gamma-Ami | 1979 |
Dementia. A brief and selective review.
Topics: Alzheimer Disease; Basal Ganglia; Brain; Brain Chemistry; Caudate Nucleus; Creutzfeldt-Jakob Syndrom | 1976 |
Biochemical approaches to dementia.
Topics: Adult; Aged; Alzheimer Disease; Animals; Brain; Cerebrovascular Circulation; Dementia; gamma-Aminobu | 1977 |
Neurotransmitters in the cerebral cortex.
Topics: Acetylcholine; Alzheimer Disease; Animals; Cerebral Cortex; Cerebrovascular Disorders; Dementia; Dop | 1986 |
Petit mal epilepsy: a review and integration of recent information.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepines; Brain; Cognition; Dementia; Electroencephalogra | 1986 |
[Pathophysiology of dementia].
Topics: Acetylcholine; Aged; Aging; Alzheimer Disease; Brain; Brain Chemistry; Dementia; Dopamine; gamma-Ami | 1985 |
5 trials available for gamma-aminobutyric acid and Amentia
Article | Year |
---|---|
The response of agitated behavior to pain management in persons with dementia.
Topics: Acetaminophen; Aged, 80 and over; Analgesics; Buprenorphine; Delayed-Action Preparations; Dementia; | 2014 |
Impact of a stepwise protocol for treating pain on pain intensity in nursing home patients with dementia: a cluster randomized trial.
Topics: Acetaminophen; Activities of Daily Living; Aged; Aged, 80 and over; Analgesics; Buprenorphine; Clini | 2014 |
Gabapentin for the treatment of behavioural alterations in dementia: preliminary 15-month investigation.
Topics: Acetates; Aged; Amines; Anti-Anxiety Agents; Comorbidity; Cyclohexanecarboxylic Acids; Dementia; Fem | 2003 |
Neurotransmitter systems in aging and senile dementia.
Topics: Acetylcholine; Aged; Aging; Animals; Brain; Choline; Clinical Trials as Topic; Dementia; Dopamine; g | 1981 |
Effectiveness of gabapentin for the treatment of behavioral disorders in dementia.
Topics: Acetates; Aged; Aged, 80 and over; Amines; Anti-Anxiety Agents; Behavioral Symptoms; Cyclohexanecarb | 2000 |
46 other studies available for gamma-aminobutyric acid and Amentia
Article | Year |
---|---|
Metabolism and Memory: Obesity, Diabetes, and Dementia.
Topics: Dementia; gamma-Aminobutyric Acid; Humans; Islet Amyloid Polypeptide; Memory; Obesity | 2017 |
The science of tea's mood-altering magic.
Topics: Adenosine; Affect; Alpha Rhythm; Animals; Antioxidants; Behavior; Beta Rhythm; Blood-Brain Barrier; | 2019 |
A high-quality RCT documents that elderly with dementia, the most neglected pain patients, have effective and safe pain relief from paracetamol alone or with buprenorphine patch.
Topics: Acetaminophen; Analgesics; Buprenorphine; Clinical Protocols; Dementia; Female; gamma-Aminobutyric A | 2014 |
Prognostic prediction in patients with hip fracture: risk factors predicting difficulties with discharge to own home.
Topics: Age Distribution; Aged; Aged, 80 and over; Comorbidity; Dementia; Disability Evaluation; Female; Fem | 2011 |
Decrease of GABAergic markers and arc protein expression in the frontal cortex by intraventricular 192 IgG-saporin.
Topics: Acetylcholinesterase; Animals; Antibodies, Monoclonal; Blotting, Western; Choline O-Acetyltransferas | 2011 |
Gabapentin in the treatment of dementia-associated nocturnal agitation.
Topics: Aged; Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Darkness; Dementia; Female; Gabapent | 2011 |
Glutamate metabolism is impaired in transgenic mice with tau hyperphosphorylation.
Topics: Acetates; Animals; Astrocytes; Cerebellar Cortex; Dementia; Female; gamma-Aminobutyric Acid; Glucose | 2013 |
[Effects of gamma-aminobutyric acid-pyridoxine in presenile and senile psychiatric disorders].
Topics: Amino Acids; Dementia; gamma-Aminobutyric Acid; Humans; Mental Disorders; Psychotic Disorders; Pyrid | 1962 |
Carbamazepine encephalopathy masquerading as Creutzfeldt-Jakob disease.
Topics: Aged; Amines; Analgesics, Non-Narcotic; Atrophy; Basal Ganglia; Brain; Brain Damage, Chronic; Carbam | 2005 |
Delirium as a disorder of consciousness.
Topics: Acetylcholine; Aged; Arousal; Attention; Awareness; Brain Stem; Cerebral Cortex; Child; Consciousnes | 2007 |
Chronic pentylenetetrazole but not donepezil treatment rescues spatial cognition in Ts65Dn mice, a model for Down syndrome.
Topics: Acetylcholine; Animals; Brain; Cholinesterase Inhibitors; Cognition Disorders; Dementia; Disease Mod | 2008 |
Aging and neurotransmitter systems.
Topics: Adult; Aged; Aging; Brain; Catecholamines; Choline O-Acetyltransferase; Dementia; gamma-Aminobutyric | 1980 |
Neurotransmitters and CNS disease. Dementia.
Topics: Acetylcholine; Aged; Alzheimer Disease; Cerebral Cortex; Choline O-Acetyltransferase; Dementia; Dopa | 1982 |
Neurotransmitters of the cerebral cortex in senile dementia of Alzheimer type.
Topics: Aged; Alzheimer Disease; Cerebral Cortex; Choline O-Acetyltransferase; Dementia; Enkephalin, Methion | 1982 |
Amino acid release from biopsy samples of temporal neocortex from patients with Alzheimer's disease.
Topics: Acetylcholine; Alzheimer Disease; Amino Acids; Aspartic Acid; Dementia; gamma-Aminobutyric Acid; Glu | 1983 |
Decreased CSF concentrations of homovanillic acid and gamma-aminobutyric acid in Alzheimer's disease. Age- or disease-related modifications?
Topics: Age Factors; Aged; Aging; Alzheimer Disease; Brain Chemistry; Dementia; Female; gamma-Aminobutyric A | 1982 |
Gamma-aminobutyric acid (GABA) in cerebrospinal fluid.
Topics: Adult; Behcet Syndrome; Cerebellar Diseases; Cerebral Infarction; Dementia; Female; gamma-Aminobutyr | 1983 |
[Huntington chorea: report of 16 cases].
Topics: Adult; Aged; Brain Diseases; Chlorpromazine; Dementia; Diagnosis, Differential; Female; gamma-Aminob | 1983 |
Free and conjugated GABA in human cerebrospinal fluid: effect of degenerative neurologic diseases and isoniazid.
Topics: Adult; Age Factors; Aged; Cerebellar Ataxia; Dementia; Epilepsy; gamma-Aminobutyric Acid; Humans; Hu | 1984 |
Striatal dopamine receptors in Alzheimer-type dementia.
Topics: Aged; Alzheimer Disease; Choline O-Acetyltransferase; Dementia; Female; gamma-Aminobutyric Acid; Hom | 1984 |
Levels of gamma-aminobutyric acid in cerebrospinal fluid in various neurologic disorders.
Topics: Brain Chemistry; Cerebellar Diseases; Creatine Kinase; Dementia; Diet; Encephalitis; Epilepsy; gamma | 1980 |
Gamma-aminobutyric acid and homovanillic acid concentration in the CSF of patients with senile dementia of Alzheimer's type.
Topics: Aged; Alzheimer Disease; Dementia; Female; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Middl | 1984 |
Correlation of cortical cholinergic and GABA deficits with quantitative neuropathological findings in senile dementia.
Topics: Alzheimer Disease; Brain; Choline O-Acetyltransferase; Cholinergic Fibers; Dementia; gamma-Aminobuty | 1984 |
Potential therapies in aging and senile dementias.
Topics: Acetylcholine; Aging; Alzheimer Disease; Animals; Cerebrovascular Circulation; Dementia; gamma-Amino | 1982 |
A post-mortem study of the cholinergic and GABA systems in senile dementia.
Topics: Aged; Alzheimer Disease; Brain; Cerebral Cortex; Choline O-Acetyltransferase; Dementia; gamma-Aminob | 1982 |
Hippocampal free amino acids in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Amino Acids; Arginine; Aspartic Acid; Dementia; gamma-Aminobutyric Acid; Gl | 1980 |
Gabapentin in geriatric psychiatry patients.
Topics: Acetates; Aged; Aged, 80 and over; Alzheimer Disease; Amines; Anticonvulsants; Bipolar Disorder; Cyc | 1998 |
Gabapentin for disruptive behaviour in an elderly demented patient.
Topics: Acetates; Aged; Aged, 80 and over; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dementia; D | 1998 |
A retrospective chart review of gabapentin for the treatment of aggressive and agitated behavior in patients with dementias.
Topics: Acetates; Aged; Aged, 80 and over; Aggression; Amines; Antimanic Agents; California; Cyclohexanecarb | 2000 |
FK960, a novel potential anti-dementia drug, enhances high K(+)-evoked release of somatostatin from rat hippocampal slices.
Topics: Acetylcholine; Animals; Aspartic Acid; Benzamides; Dementia; gamma-Aminobutyric Acid; Hippocampus; I | 2001 |
Gabapentin-induced worsening of neuropsychiatric symptoms in dementia with lewy bodies: case reports.
Topics: Acetates; Aged; Amines; Cyclohexanecarboxylic Acids; Dementia; Female; Gabapentin; gamma-Aminobutyri | 2002 |
Biochemical changes in Alzheimer's disease-senile dementia: neurotransmitters in senile dementia of the Alzheimer's type.
Topics: Acetylcholine; Acetylcholinesterase; Aged; Alzheimer Disease; Brain; Choline O-Acetyltransferase; De | 1979 |
Letter: Extrapyramidal diseases and dementia.
Topics: Aged; Brain; Dementia; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Parkinson Disease | 1975 |
Choline in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Cerebral Cortex; Choline; Choline O-Acetyltransferase; Dementia; gamma-Amin | 1977 |
Cerebrospinal fluid gamma-aminobutyric acid in neurologic disease.
Topics: Aminobutyrates; Cerebrovascular Disorders; Dementia; Epilepsy, Post-Traumatic; Epilepsy, Temporal Lo | 1976 |
Cerebrospinal fluid gamma-aminobutyric acid variations in neurological disorders.
Topics: Adolescent; Adult; Aged; Alzheimer Disease; Aminobutyrates; Child; Dementia; gamma-Aminobutyric Acid | 1977 |
Pre- and postsynaptic neurochemical alterations in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Caudate Nucleus; Choline O-Acetyltransferase; Dementia; Frontal Lobe; gamma | 1978 |
Biochemical aspects of the aging brain.
Topics: Acetylcholine; Aging; Alzheimer Disease; Brain; Cell Count; Dementia; Energy Metabolism; gamma-Amino | 1978 |
Glutamate and GABA levels in CSF from patients affected by dementia and olivo-ponto-cerebellar atrophy.
Topics: Age Factors; Aged; Aged, 80 and over; Dementia; Female; gamma-Aminobutyric Acid; Glutamates; Glutami | 1992 |
Dementia in Huntington's disease is associated with neurochemical deficits in the caudate nucleus, not the cerebral cortex.
Topics: Adult; Aged; Caudate Nucleus; Cerebral Cortex; Choline O-Acetyltransferase; Dementia; Female; gamma- | 1990 |
Progressive supranuclear palsy: relationship between extrapyramidal disturbances, dementia, and brain neurotransmitter markers.
Topics: Aged; Aspartic Acid; Basal Ganglia Diseases; Brain; Bulbar Palsy, Progressive; Choline O-Acetyltrans | 1985 |
Studies on neurotransmitter markers of the basal ganglia in Pick's disease, with special reference to dopamine reduction.
Topics: Adult; Basal Ganglia; Brain; Choline O-Acetyltransferase; Dementia; Dopamine; Female; gamma-Aminobut | 1988 |
CSF GABA in caregiver spouses of Alzheimer patients.
Topics: Alzheimer Disease; Chromatography, High Pressure Liquid; Dementia; Female; gamma-Aminobutyric Acid; | 1989 |
Effect of the 'antidementia drug' pantoyl-GABA on high affinity transport of choline and on the contents of choline and acetylcholine in rat brain.
Topics: Acetylcholine; Animals; Biological Transport, Active; Brain; Choline; Dementia; gamma-Aminobutyric A | 1988 |
[Drug therapy of Alzheimer's disease. General concepts on nootropic drugs].
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amantadine; Aminoacridines; Dementia; gamma-Aminobutyric | 1988 |
Reye-like syndrome following treatment with the pantothenic acid antagonist, calcium hopantenate.
Topics: Aged; Biopsy; Dementia; Female; gamma-Aminobutyric Acid; Humans; Liver; Microscopy, Electron; Pantot | 1988 |