gamma-aminobutyric acid has been researched along with Alloxan Diabetes in 108 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The important pathological consequences of insulin resistance arise from the detrimental effects of accumulated long-chain fatty acids and their respective acylcarnitines." | 7.83 | Decreased acylcarnitine content improves insulin sensitivity in experimental mice models of insulin resistance. ( Dambrova, M; Grinberga, S; Kuka, J; Liepinsh, E; Makarova, E; Makrecka-Kuka, M; Sevostjanovs, E; Svalbe, B; Volska, K, 2016) |
| "Dose response curves for nonsedating doses of morphine and CNSB002 given intraperitoneally alone and together in combinations were constructed for antihyperalgesic effect using paw withdrawal from noxious heat in two rat pain models: carrageenan-induced paw inflammation and streptozotocin (STZ)-induced diabetic neuropathy." | 7.76 | Studies of synergy between morphine and a novel sodium channel blocker, CNSB002, in rat models of inflammatory and neuropathic pain. ( Cooke, I; Goodchild, CS; Kolosov, A, 2010) |
| "This study determined the antihyperalgesic effect of CNSB002, a sodium channel blocker with antioxidant properties given alone and in combinations with morphine in rat models of inflammatory and neuropathic pain." | 7.76 | Studies of synergy between morphine and a novel sodium channel blocker, CNSB002, in rat models of inflammatory and neuropathic pain. ( Cooke, I; Goodchild, CS; Kolosov, A, 2010) |
| "The purpose of this study was to investigate whether taurine ameliorate the diabetic retinopathy, and to further explore the underlying mechanisms." | 7.74 | Dietary taurine supplementation ameliorates diabetic retinopathy via anti-excitotoxicity of glutamate in streptozotocin-induced Sprague-Dawley rats. ( Chen, F; Chen, K; Mi, M; Tang, Y; Wang, J; Wei, N; Xu, H; Xu, Z; Yu, X; Zeng, K; Zhang, Q; Zhu, J, 2008) |
| "The present study examines the effect of combinations of gabapentin (Neurontin) and a selective neurokinin (NK)(1) receptor antagonist, 1-(1H-indol-3-ylmethyl)-1-methyl-2-oxo-2-[(1-phenylethyl)amino]ethyl]-2-benzofuranylmethyl ester (CI-1021), in two models of neuropathic pain." | 7.71 | Gabapentin and the neurokinin(1) receptor antagonist CI-1021 act synergistically in two rat models of neuropathic pain. ( Field, MJ; Gonzalez, MI; Singh, L; Tallarida, RJ, 2002) |
| "We have shown that the glucagon irresponsiveness to hypoglycemia in diabetic rats is markedly improved by correction of hyperglycemia independent of insulin." | 7.69 | Quantitative measurement of islet glucagon response to hypoglycemia by confocal fluorescence imaging in diabetic rats: effects of phlorizin treatment. ( Cooper, RL; Rastogi, KS; Shi, ZQ; Vranic, M, 1997) |
| "Neuropathic vulvodynia is a state of vulval discomfort characterized by a burning sensation, diffuse pain, pruritus or rawness with an acute or chronic onset." | 5.42 | A streptozotocin-induced diabetic neuropathic pain model for static or dynamic mechanical allodynia and vulvodynia: validation using topical and systemic gabapentin. ( Abbas, M; Ali, G; Sewell, RD; Shahid, M; Subhan, F; Zeb, J, 2015) |
| "Here, we tested the effect of FK1706 on painful diabetic neuropathy in rat model of diabetes induced by streptozotocin (STZ)." | 5.35 | FK1706, a novel non-immunosuppressive immunophilin ligand, modifies the course of painful diabetic neuropathy. ( Matsuoka, N; Murai, N; Mutoh, S; Price, RD; Yamaji, T; Yamamoto, H; Yamazaki, S, 2008) |
| "The important pathological consequences of insulin resistance arise from the detrimental effects of accumulated long-chain fatty acids and their respective acylcarnitines." | 3.83 | Decreased acylcarnitine content improves insulin sensitivity in experimental mice models of insulin resistance. ( Dambrova, M; Grinberga, S; Kuka, J; Liepinsh, E; Makarova, E; Makrecka-Kuka, M; Sevostjanovs, E; Svalbe, B; Volska, K, 2016) |
| "Pregabalin was a very efficacious antiallodynic and analgesic drug capable of increasing the pain thresholds for tactile allodynia and thermal hyperalgesia in diabetic mice." | 3.79 | Evaluation of analgesic, antioxidant, cytotoxic and metabolic effects of pregabalin for the use in neuropathic pain. ( Gluch-Lutwin, M; Librowski, T; Nawiesniak, B; Sałat, K, 2013) |
| " Those were randomly divided into 2 groups (N=10 per group): i) EDDM (erectile dysfunction diabetes mellitus) group fed with saline and ii) EDDM+Pregabalin treated group receiving pregabalin (10 mg/k/day) by intragastric administration." | 3.79 | Effect of pregabalin on erectile function and penile NOS expression in rats with streptozotocin-induced diabetes. ( Amany, S; Heba, K, 2013) |
| "Treatment with pregabalin for 4 weeks decreases superoxide production but cannot improve erectile dysfunction in diabetic rats probably by inhibiting Ca(2)(+) channel-mediated NOS activation." | 3.79 | Effect of pregabalin on erectile function and penile NOS expression in rats with streptozotocin-induced diabetes. ( Amany, S; Heba, K, 2013) |
| "Dose response curves for nonsedating doses of morphine and CNSB002 given intraperitoneally alone and together in combinations were constructed for antihyperalgesic effect using paw withdrawal from noxious heat in two rat pain models: carrageenan-induced paw inflammation and streptozotocin (STZ)-induced diabetic neuropathy." | 3.76 | Studies of synergy between morphine and a novel sodium channel blocker, CNSB002, in rat models of inflammatory and neuropathic pain. ( Cooke, I; Goodchild, CS; Kolosov, A, 2010) |
| "This study determined the antihyperalgesic effect of CNSB002, a sodium channel blocker with antioxidant properties given alone and in combinations with morphine in rat models of inflammatory and neuropathic pain." | 3.76 | Studies of synergy between morphine and a novel sodium channel blocker, CNSB002, in rat models of inflammatory and neuropathic pain. ( Cooke, I; Goodchild, CS; Kolosov, A, 2010) |
| "The purpose of this study was to investigate whether taurine ameliorate the diabetic retinopathy, and to further explore the underlying mechanisms." | 3.74 | Dietary taurine supplementation ameliorates diabetic retinopathy via anti-excitotoxicity of glutamate in streptozotocin-induced Sprague-Dawley rats. ( Chen, F; Chen, K; Mi, M; Tang, Y; Wang, J; Wei, N; Xu, H; Xu, Z; Yu, X; Zeng, K; Zhang, Q; Zhu, J, 2008) |
| "The present study examines the effect of combinations of gabapentin (Neurontin) and a selective neurokinin (NK)(1) receptor antagonist, 1-(1H-indol-3-ylmethyl)-1-methyl-2-oxo-2-[(1-phenylethyl)amino]ethyl]-2-benzofuranylmethyl ester (CI-1021), in two models of neuropathic pain." | 3.71 | Gabapentin and the neurokinin(1) receptor antagonist CI-1021 act synergistically in two rat models of neuropathic pain. ( Field, MJ; Gonzalez, MI; Singh, L; Tallarida, RJ, 2002) |
| "We have shown that the glucagon irresponsiveness to hypoglycemia in diabetic rats is markedly improved by correction of hyperglycemia independent of insulin." | 3.69 | Quantitative measurement of islet glucagon response to hypoglycemia by confocal fluorescence imaging in diabetic rats: effects of phlorizin treatment. ( Cooper, RL; Rastogi, KS; Shi, ZQ; Vranic, M, 1997) |
| "The levels of gamma aminobutyric acid decreased, while glutamic acid and aspartic acid levels increased in the forebrain, and decreased in the mid and hind brain regions of frog, Rana cyanophlictis during alloxan diabetes." | 3.65 | Neurochemical correlates of alloxan diabetes: gamma amino butyric acid of amphibian brain. ( Nagaraj, JS, 1977) |
| " Soy fermentation can improve the bioavailability of these precious nutrients." | 1.91 | Soy yoghurts produced with efficient GABA (γ-aminobutyric acid)-producing ( Chen, LG; Chu, C; Hsieh, CW; Weng, BB; Yuan, HD, 2023) |
| " The highest dosage of GABA yogurt had a greater beneficial effect with respect to insulin resistance than the lower dosages." | 1.56 | Effect of γ-aminobutyric acid-rich yogurt on insulin sensitivity in a mouse model of type 2 diabetes mellitus. ( Chen, L; Li, X; Lu, Y; Lu, Z; Zhu, X, 2020) |
| " There was a dose-response relationship between the above result and the 0." | 1.51 | [γ-aminobutyric acid fortified rice alleviated oxidative stress and pancreatic injury in type 2 diabetic mice]. ( Gao, Q; Jiang, Y; Le, G; Luo, T; Shi, Y; Xu, Y, 2019) |
| "Von Frey filaments were used to assess tactile allodynia." | 1.48 | Evaluation of the neonatal streptozotocin model of diabetes in rats: Evidence for a model of neuropathic pain. ( Barragán-Iglesias, P; Delgado-Lezama, R; Granados-Soto, V; Hong, E; Loeza-Alcocer, E; Oidor-Chan, VH; Pineda-Farias, JB; Price, TJ; Salinas-Abarca, AB; Sánchez-Mendoza, A; Velazquez-Lagunas, I, 2018) |
| "The treatment with gabapentin or LLLT significantly decreased the raised level in total cholesterol in DNP but could not decrease the elevated level of triglycerides, while LDL cholesterol decreased significantly in DNP treated with gabapentin but not affected by LLLT." | 1.48 | Efficiencies of Low-Level Laser Therapy (LLLT) and Gabapentin in the Management of Peripheral Neuropathy: Diabetic Neuropathy. ( Abdel-Wahhab, KG; Daoud, EM; El Gendy, A; Mannaa, FA; Mourad, HH; Saber, MM, 2018) |
| " Pharmacokinetic analysis was based on plasma and urine data concentrations." | 1.48 | The role of organic cation transporter 2 inhibitor cimetidine, experimental diabetes mellitus and metformin on gabapentin pharmacokinetics in rats. ( Baviera, AM; Benzi, JRL; de Moraes, NV; Stevens, JH; Yamamoto, PA, 2018) |
| "No differences in pharmacokinetic parameters were observed between vehicle + GAB × cimetidine + GAB and vehicle + GAB × metformin + GAB groups." | 1.48 | The role of organic cation transporter 2 inhibitor cimetidine, experimental diabetes mellitus and metformin on gabapentin pharmacokinetics in rats. ( Baviera, AM; Benzi, JRL; de Moraes, NV; Stevens, JH; Yamamoto, PA, 2018) |
| "Diabetic retinopathy is a severe retinal complication that diabetic patients are susceptible to present." | 1.46 | Retinal exposure to high glucose condition modifies the GABAergic system: Regulation by nitric oxide. ( Calaza, KC; Carpi-Santos, R; Maggesissi, RS; von Seehausen, MP, 2017) |
| "Type 1 diabetes was induced by injecting the mice with streptozotocin (STZ)." | 1.46 | Paracrine GABA and insulin regulate pancreatic alpha cell proliferation in a mouse model of type 1 diabetes. ( Feng, AL; Feng, Q; Gui, L; Kaltsidis, G; Lu, WY; Xiang, YY, 2017) |
| "Using 3 rat models of neuropathic pain of toxic (oxaliplatin/OXA), metabolic (streptozocin/STZ), and traumatic (sciatic nerve ligation/CCI [chronic constriction nerve injury]) etiologies, we investigated the antihypersensitivity effect of acute and repeated agomelatine administration." | 1.46 | Agomelatine: a new opportunity to reduce neuropathic pain-preclinical evidence. ( Authier, N; Bertrand, M; Chapuy, E; Chenaf, C; Courteix, C; Eschalier, A; Gabriel, C; Libert, F; Marchand, F; Mocaër, E, 2017) |
| "Hypertension is considered an independent risk factor for cardiovascular mortality in diabetic patients." | 1.42 | Role of GABAB receptor and L-Arg in GABA-induced vasorelaxation in non-diabetic and streptozotocin-induced diabetic rat vessels. ( Farsi, L; Keshavarz, M; Kharazmi, F; Rezaei, S; Soltani, N, 2015) |
| "Neuropathic vulvodynia is a state of vulval discomfort characterized by a burning sensation, diffuse pain, pruritus or rawness with an acute or chronic onset." | 1.42 | A streptozotocin-induced diabetic neuropathic pain model for static or dynamic mechanical allodynia and vulvodynia: validation using topical and systemic gabapentin. ( Abbas, M; Ali, G; Sewell, RD; Shahid, M; Subhan, F; Zeb, J, 2015) |
| "Neuropathic pain is currently an insufficiently treated clinical condition." | 1.40 | Soluble epoxide hydrolase inhibition is antinociceptive in a mouse model of diabetic neuropathy. ( Hammock, BD; Inceoglu, B; Wagner, K; Yang, J, 2014) |
| "Diabetic rats developed mechanical hyperalgesia within 3 weeks after streptozocin injection and exhibited reduced SNCV and impaired myelin/axonal structure." | 1.40 | Anti-allodynic and neuroprotective effects of koumine, a Benth alkaloid, in a rat model of diabetic neuropathy. ( Huang, HH; Ling, Q; Liu, M; Wu, MX; Xu, Y; Yang, J; Yu, CX, 2014) |
| "Koumine was given at a dose range of 0." | 1.40 | Anti-allodynic and neuroprotective effects of koumine, a Benth alkaloid, in a rat model of diabetic neuropathy. ( Huang, HH; Ling, Q; Liu, M; Wu, MX; Xu, Y; Yang, J; Yu, CX, 2014) |
| "Koumine treatment of diabetic rats decreased neuropathic pain behavior as early as after the first administration." | 1.40 | Anti-allodynic and neuroprotective effects of koumine, a Benth alkaloid, in a rat model of diabetic neuropathy. ( Huang, HH; Ling, Q; Liu, M; Wu, MX; Xu, Y; Yang, J; Yu, CX, 2014) |
| " Below we describe the preliminary evaluation of support vector machine in the regression mode (SVR) application for the prediction of maximal antiallodynic effect of a new derivative of dihydrofuran-2-one (LPP1) used in combination with pregabalin (PGB) in the streptozocin-induced neuropathic pain model in mice." | 1.39 | The application of support vector regression for prediction of the antiallodynic effect of drug combinations in the mouse model of streptozocin-induced diabetic neuropathy. ( Sałat, K; Sałat, R, 2013) |
| "Hypertension is considered an independent risk factor for cardiovascular mortality in diabetic patients." | 1.39 | GABA-induced vasorelaxation mediated by nitric oxide and GABAA receptor in non diabetic and streptozotocin-induced diabetic rat vessels. ( Bahrami, A; Farsi, L; Kamran, M; Keshavarz, M; Soltani, N, 2013) |
| "The threshold of mechanical hyperalgesia was also significantly elevated." | 1.38 | Protective effects of combined therapy of gliclazide with curcumin in experimental diabetic neuropathy in rats. ( Ahmed, AA; Al-Rasheed, NM; Attia, HN; Kenawy, SA; Maklad, YA, 2012) |
| " Analysis of the log dose-response curves for oxcarbazepine or gabapentin in a presence of amitriptyline and oxcarbazepine or gabapentin applied alone, revealed a synergism in oxcarbazepine-amitriptyline and additivity in gabapentin-amitriptyline combination." | 1.36 | Analysis of the antinociceptive interactions in two-drug combinations of gabapentin, oxcarbazepine and amitriptyline in streptozotocin-induced diabetic mice. ( Bosković, B; Micov, AM; Prostran, MS; Stepanović-Petrović, RM; Tomić, MA; Ugresić, ND; Vucković, SM, 2010) |
| "Hyperalgesia is one of the debilitating complications of diabetes." | 1.36 | Diabetic thermal hyperalgesia: role of TRPV1 and CB1 receptors of periaqueductal gray. ( Ghazi-Khansari, M; Jaberi, E; Mohammadi-Farani, A; Sahebgharani, M; Sepehrizadeh, Z, 2010) |
| "Here, we tested the effect of FK1706 on painful diabetic neuropathy in rat model of diabetes induced by streptozotocin (STZ)." | 1.35 | FK1706, a novel non-immunosuppressive immunophilin ligand, modifies the course of painful diabetic neuropathy. ( Matsuoka, N; Murai, N; Mutoh, S; Price, RD; Yamaji, T; Yamamoto, H; Yamazaki, S, 2008) |
| " Here we determined the antinociceptive effect of chronic administration of neramexane and compared its effect with that of memantine and gabapentin in a rat model of diabetic neuropathic pain." | 1.35 | Antinociceptive effects of chronic administration of uncompetitive NMDA receptor antagonists in a rat model of diabetic neuropathic pain. ( Chen, SR; Pan, HL; Samoriski, G, 2009) |
| "The ability of bicuculline to alleviate allodynia and formalin-evoked hyperalgesia in diabetic rats is consistent with a reversal of the properties of GABA predicted by reduced spinal KCC2 and suggests that reduced KCC2 expression and increased GABA release contribute to spinally mediated hyperalgesia in diabetes." | 1.35 | Allodynia and hyperalgesia in diabetic rats are mediated by GABA and depletion of spinal potassium-chloride co-transporters. ( Calcutt, NA; Jolivalt, CG; Lee, CA; Ramos, KM, 2008) |
| "Pretreatment with gabapentin prevented the upregulation of GFAP, S100B, and NSE in all brain regions of diabetic rats." | 1.33 | Novel role for gabapentin in neuroprotection of central nervous system in streptozotocine-induced diabetic rats. ( Baydas, G; Donder, E; Sonkaya, E; Tuzcu, M; Yasar, A, 2005) |
| " There is also a fairly broad consensus that gabapentin is safe and well tolerated, but the side-effect profile of gabapentin has not been adequately assessed in pain populations." | 1.33 | Adverse effects of gabapentin and lack of anti-allodynic efficacy of amitriptyline in the streptozotocin model of painful diabetic neuropathy. ( Bourin, C; Chen, P; Hogan, JB; Leet, JE; Lindner, MD; Machet, F; McElroy, JF; Stock, DA, 2006) |
| " Amitriptyline did not attenuate STZ-induced mechanical allodynia, even after chronic administration of high doses." | 1.33 | Adverse effects of gabapentin and lack of anti-allodynic efficacy of amitriptyline in the streptozotocin model of painful diabetic neuropathy. ( Bourin, C; Chen, P; Hogan, JB; Leet, JE; Lindner, MD; Machet, F; McElroy, JF; Stock, DA, 2006) |
| "Lactic acidosis has been implicated; however, increases in the excitotoxic amino acid glutamate, which correlate with increased neuronal damage, may be the cause for the increased damage seen in hyperglycemic stroke." | 1.31 | The effect of streptozotocin-induced diabetes on the release of excitotoxic and other amino acids from the ischemic rat cerebral cortex. ( Diaz, FG; Guyot, LL; O'Regan, MH; Phillis, JW; Song, D, 2001) |
| "Gabapentin displays efficacy against abnormal sensory processing in diabetic rats and may be of benefit for treating painful diabetic neuropathy." | 1.30 | Gabapentin prevents hyperalgesia during the formalin test in diabetic rats. ( Calcutt, NA; Ceseña, RM, 1999) |
| "Gabapentin was without effect in controls but suppressed (P < 0." | 1.30 | Gabapentin prevents hyperalgesia during the formalin test in diabetic rats. ( Calcutt, NA; Ceseña, RM, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (6.48) | 18.7374 |
| 1990's | 14 (12.96) | 18.2507 |
| 2000's | 22 (20.37) | 29.6817 |
| 2010's | 51 (47.22) | 24.3611 |
| 2020's | 14 (12.96) | 2.80 |
| Authors | Studies |
|---|---|
| Zaręba, P | 1 |
| Gryzło, B | 1 |
| Malawska, K | 1 |
| Sałat, K | 3 |
| Höfner, GC | 1 |
| Nowaczyk, A | 1 |
| Fijałkowski, Ł | 1 |
| Rapacz, A | 1 |
| Podkowa, A | 1 |
| Furgała, A | 1 |
| Żmudzki, P | 1 |
| Wanner, KT | 1 |
| Malawska, B | 1 |
| Kulig, K | 1 |
| Hosseini Dastgerdi, A | 1 |
| Sharifi, M | 2 |
| Soltani, N | 5 |
| Yazdanimoghaddam, F | 1 |
| Ghasemi, M | 1 |
| Teamparvar, H | 1 |
| Aghaei, M | 1 |
| Rezazadeh, H | 1 |
| Zadhoush, F | 1 |
| Rathwa, N | 1 |
| Parmar, N | 1 |
| Palit, SP | 1 |
| Patel, R | 1 |
| Bhaskaran, RS | 1 |
| Ramachandran, AV | 1 |
| Begum, R | 1 |
| Sarnobat, D | 1 |
| Charlotte Moffett, R | 1 |
| Flatt, PR | 1 |
| Irwin, N | 1 |
| Tarasov, AI | 1 |
| Tykhonenko, T | 1 |
| Guzyk, M | 1 |
| Tykhomyrov, A | 1 |
| Korsa, V | 1 |
| Yanitska, L | 1 |
| Kuchmerovska, T | 1 |
| Gu, L | 1 |
| Cui, X | 1 |
| Lin, X | 1 |
| Yang, J | 4 |
| Wei, R | 1 |
| Hong, T | 1 |
| Yang, K | 1 |
| Lagunas-Rangel, FA | 1 |
| Koshelev, D | 1 |
| Nedorubov, A | 1 |
| Kosheleva, L | 1 |
| Trukhan, V | 1 |
| Rabinovitch, A | 1 |
| Schiöth, HB | 1 |
| Levit, S | 1 |
| Weng, BB | 1 |
| Yuan, HD | 1 |
| Chen, LG | 1 |
| Chu, C | 1 |
| Hsieh, CW | 1 |
| Caramelo, B | 1 |
| Monteiro-Alfredo, T | 1 |
| Martins, J | 1 |
| Sereno, J | 1 |
| Castelhano, J | 1 |
| Manadas, B | 1 |
| Castelo-Branco, M | 1 |
| Matafome, P | 1 |
| Bagheri, J | 1 |
| Fallahnezhad, S | 1 |
| Alipour, N | 1 |
| Babaloo, H | 1 |
| Tahmasebi, F | 1 |
| Kheradmand, H | 1 |
| Sazegar, G | 1 |
| Haghir, H | 1 |
| Moore-Dotson, JM | 1 |
| Eggers, ED | 1 |
| Yi, Z | 1 |
| Waseem Ghani, M | 1 |
| Ghani, H | 1 |
| Jiang, W | 1 |
| Waseem Birmani, M | 1 |
| Ye, L | 1 |
| Bin, L | 1 |
| Cun, LG | 1 |
| Lilong, A | 1 |
| Mei, X | 1 |
| Li, X | 2 |
| Chen, L | 1 |
| Zhu, X | 1 |
| Lu, Z | 1 |
| Lu, Y | 1 |
| Zhu, Y | 1 |
| Devi, S | 1 |
| Kumar, M | 1 |
| Dahiya, RS | 1 |
| Stepanović-Petrović, R | 1 |
| Micov, A | 1 |
| Tomić, M | 1 |
| Pecikoza, U | 1 |
| Carpi-Santos, R | 1 |
| Maggesissi, RS | 1 |
| von Seehausen, MP | 1 |
| Calaza, KC | 1 |
| Prud'homme, GJ | 2 |
| Glinka, Y | 1 |
| Kurt, M | 1 |
| Liu, W | 1 |
| Wang, Q | 2 |
| Sohrabipour, S | 1 |
| Sharifi, MR | 1 |
| Talebi, A | 1 |
| Barragán-Iglesias, P | 1 |
| Oidor-Chan, VH | 1 |
| Loeza-Alcocer, E | 1 |
| Pineda-Farias, JB | 1 |
| Velazquez-Lagunas, I | 1 |
| Salinas-Abarca, AB | 1 |
| Hong, E | 1 |
| Sánchez-Mendoza, A | 1 |
| Delgado-Lezama, R | 1 |
| Price, TJ | 1 |
| Granados-Soto, V | 1 |
| Abdel-Wahhab, KG | 1 |
| Daoud, EM | 1 |
| El Gendy, A | 1 |
| Mourad, HH | 1 |
| Mannaa, FA | 1 |
| Saber, MM | 1 |
| Benzi, JRL | 1 |
| Yamamoto, PA | 1 |
| Stevens, JH | 1 |
| Baviera, AM | 1 |
| de Moraes, NV | 1 |
| Shin, JS | 1 |
| Kim, JM | 1 |
| Min, BH | 1 |
| Chung, H | 1 |
| Park, CG | 1 |
| Gao, Q | 1 |
| Jiang, Y | 1 |
| Luo, T | 1 |
| Xu, Y | 2 |
| Le, G | 1 |
| Shi, Y | 1 |
| Kamran, M | 1 |
| Bahrami, A | 1 |
| Keshavarz, M | 2 |
| Farsi, L | 2 |
| Amany, S | 1 |
| Heba, K | 1 |
| García-Hernández, L | 1 |
| Navarrete-Vázquez, G | 1 |
| González-Trujano, ME | 1 |
| López-Muñoz, FJ | 1 |
| Déciga-Campos, M | 1 |
| Sałat, R | 1 |
| Librowski, T | 1 |
| Nawiesniak, B | 1 |
| Gluch-Lutwin, M | 1 |
| Chan, O | 2 |
| Paranjape, SA | 1 |
| Horblitt, A | 2 |
| Zhu, W | 2 |
| Sherwin, RS | 1 |
| Tian, J | 1 |
| Dang, H | 1 |
| Chen, Z | 1 |
| Guan, A | 1 |
| Jin, Y | 1 |
| Atkinson, MA | 1 |
| Kaufman, DL | 1 |
| Arbeláez, AM | 1 |
| Cryer, PE | 1 |
| Cherng, SH | 1 |
| Huang, CY | 1 |
| Kuo, WW | 1 |
| Lai, SE | 1 |
| Tseng, CY | 1 |
| Lin, YM | 1 |
| Tsai, FJ | 1 |
| Wang, HF | 1 |
| Ling, Q | 1 |
| Liu, M | 1 |
| Wu, MX | 1 |
| Huang, HH | 1 |
| Yu, CX | 1 |
| Wagner, K | 1 |
| Inceoglu, B | 2 |
| Hammock, BD | 2 |
| Blake, CB | 1 |
| Smith, BN | 2 |
| Purwana, I | 1 |
| Zheng, J | 1 |
| Deurloo, M | 1 |
| Son, DO | 1 |
| Zhang, Z | 1 |
| Liang, C | 1 |
| Shen, E | 1 |
| Tadkase, A | 1 |
| Feng, ZP | 1 |
| Li, Y | 1 |
| Hasilo, C | 1 |
| Paraskevas, S | 1 |
| Bortell, R | 1 |
| Greiner, DL | 1 |
| Atkinson, M | 1 |
| Son, H | 1 |
| Jung, S | 1 |
| Kim, JY | 1 |
| Goo, YM | 1 |
| Cho, KM | 1 |
| Lee, DH | 1 |
| Roh, GS | 1 |
| Kang, SS | 1 |
| Cho, GJ | 1 |
| Choi, WS | 1 |
| Kim, HJ | 2 |
| Castilho, Á | 1 |
| Ambrósio, AF | 1 |
| Hartveit, E | 1 |
| Veruki, ML | 1 |
| Kharazmi, F | 1 |
| Rezaei, S | 1 |
| Nguyen, HT | 1 |
| Bhattarai, JP | 1 |
| Park, SJ | 1 |
| Lee, JC | 1 |
| Cho, DH | 1 |
| Han, SK | 1 |
| Ali, G | 1 |
| Subhan, F | 1 |
| Abbas, M | 1 |
| Zeb, J | 1 |
| Shahid, M | 1 |
| Sewell, RD | 1 |
| Liepinsh, E | 1 |
| Makrecka-Kuka, M | 1 |
| Makarova, E | 1 |
| Volska, K | 1 |
| Svalbe, B | 1 |
| Sevostjanovs, E | 1 |
| Grinberga, S | 1 |
| Kuka, J | 1 |
| Dambrova, M | 1 |
| Reda, HM | 1 |
| Zaitone, SA | 1 |
| Moustafa, YM | 1 |
| Marques, TM | 1 |
| Patterson, E | 1 |
| Wall, R | 1 |
| O'Sullivan, O | 1 |
| Fitzgerald, GF | 1 |
| Cotter, PD | 1 |
| Dinan, TG | 1 |
| Cryan, JF | 1 |
| Ross, RP | 1 |
| Stanton, C | 1 |
| Boychuk, CR | 1 |
| Larsson, M | 1 |
| Lietzau, G | 1 |
| Nathanson, D | 1 |
| Östenson, CG | 1 |
| Mallard, C | 1 |
| Johansson, ME | 1 |
| Nyström, T | 1 |
| Patrone, C | 1 |
| Darsalia, V | 1 |
| Chenaf, C | 1 |
| Chapuy, E | 1 |
| Libert, F | 1 |
| Marchand, F | 2 |
| Courteix, C | 1 |
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2 reviews available for gamma-aminobutyric acid and Alloxan Diabetes
| Article | Year |
|---|---|
Gimmicks of gamma-aminobutyric acid (GABA) in pancreatic β-cell regeneration through transdifferentiation of pancreatic α- to β-cells.
Topics: Animals; Cell Transdifferentiation; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; gamm | 2020 |
Autocrine regulation of insulin secretion.
Topics: Adenosine Triphosphate; Animals; Autocrine Communication; Diabetes Mellitus, Experimental; Diabetes | 2012 |
106 other studies available for gamma-aminobutyric acid and Alloxan Diabetes
| Article | Year |
|---|---|
Novel mouse GABA uptake inhibitors with enhanced inhibitory activity toward mGAT3/4 and their effect on pain threshold in mice.
Topics: Analgesics; Animals; Diabetes Mellitus, Experimental; GABA Plasma Membrane Transport Proteins; GABA | 2020 |
GABA administration improves liver function and insulin resistance in offspring of type 2 diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Endocrinology; Female; gamma-A | 2021 |
Long-term GABA administration improves FNDC5, TFAM, and UCP3 mRNA expressions in the skeletal muscle and serum irisin levels in chronic type 2 diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Fibronectins; gamma-Aminobutyri | 2022 |
Calorie restriction potentiates the therapeutic potential of GABA in managing type 2 diabetes in a mouse model.
Topics: Animals; Blood Glucose; Caloric Restriction; Diabetes Mellitus, Experimental; Diabetes Mellitus, Typ | 2022 |
GABA and insulin but not nicotinamide augment α- to β-cell transdifferentiation in insulin-deficient diabetic mice.
Topics: Animals; Blood Glucose; Cell Transdifferentiation; Diabetes Mellitus, Experimental; gamma-Aminobutyr | 2022 |
Modulatory effects of vitamin B3 and its derivative on the levels of apoptotic and vascular regulators and cytoskeletal proteins in diabetic rat brain as signs of neuroprotection.
Topics: Animals; Brain; Cytoskeletal Proteins; Diabetes Mellitus, Experimental; gamma-Aminobutyric Acid; Hyp | 2022 |
γ-aminobutyric acid modulates α-cell hyperplasia but not β-cell regeneration induced by glucagon receptor antagonism in type 1 diabetic mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; gamma-Aminobutyr | 2023 |
Triple drug therapy with GABA, sitagliptin, and omeprazole prevents type 1 diabetes onset and promotes its reversal in non-obese diabetic mice.
Topics: Animals; C-Peptide; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Dipeptidyl-Peptidase | 2022 |
Soy yoghurts produced with efficient GABA (γ-aminobutyric acid)-producing
Topics: Animals; Diabetes Mellitus, Experimental; Fermentation; gamma-Aminobutyric Acid; Gastrointestinal Mi | 2023 |
Functional imaging and neurochemistry identify in vivo neuroprotection mechanisms counteracting excitotoxicity and neurovascular changes in the hippocampus and visual cortex of obese and type 2 diabetic animal models.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; gamma-Aminobutyric Acid; Glutam | 2023 |
Maternal diabetes decreases the expression of GABA
Topics: Animals; Diabetes Mellitus, Experimental; Female; gamma-Aminobutyric Acid; Insulin; Male; Rats; Rats | 2023 |
Reductions in Calcium Signaling Limit Inhibition to Diabetic Retinal Rod Bipolar Cells.
Topics: Amacrine Cells; Animals; Blood Glucose; Calcium Signaling; Diabetes Mellitus, Experimental; Diabetes | 2019 |
Effect of γ-aminobutyric acid-rich yogurt on insulin sensitivity in a mouse model of type 2 diabetes mellitus.
Topics: Animals; Blood Glucose; Cholesterol, HDL; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2 | 2020 |
Evaluation of Gamma Amino Butyric Acid (GABA) and Glibenclamide Combination Therapy in Streptozotocin Induced Diabetes.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; gamma-Aminobutyric Acid; Glyburide; Humans; | 2021 |
Levetiracetam synergizes with gabapentin, pregabalin, duloxetine and selected antioxidants in a mouse diabetic painful neuropathy model.
Topics: Amines; Analgesics; Animals; Anticonvulsants; Antioxidants; Cyclohexanecarboxylic Acids; Diabetes Me | 2017 |
Retinal exposure to high glucose condition modifies the GABAergic system: Regulation by nitric oxide.
Topics: Animals; Chickens; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Dose-Response Relationship | 2017 |
The anti-aging protein Klotho is induced by GABA therapy and exerts protective and stimulatory effects on pancreatic beta cells.
Topics: Aging; Animals; Cell Proliferation; Cell Survival; Cells, Cultured; Diabetes Mellitus, Experimental; | 2017 |
GABA dramatically improves glucose tolerance in streptozotocin-induced diabetic rats fed with high-fat diet.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; | 2018 |
Evaluation of the neonatal streptozotocin model of diabetes in rats: Evidence for a model of neuropathic pain.
Topics: Activating Transcription Factor 3; Amines; Animals; Animals, Newborn; Astrocytes; Cyclohexanecarboxy | 2018 |
Efficiencies of Low-Level Laser Therapy (LLLT) and Gabapentin in the Management of Peripheral Neuropathy: Diabetic Neuropathy.
Topics: Amines; Animals; Combined Modality Therapy; Creatinine; Cyclohexanecarboxylic Acids; Cytokines; Diab | 2018 |
The role of organic cation transporter 2 inhibitor cimetidine, experimental diabetes mellitus and metformin on gabapentin pharmacokinetics in rats.
Topics: Amines; Animals; Cimetidine; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Gabapenti | 2018 |
Absence of spontaneous regeneration of endogenous pancreatic β-cells after chemical-induced diabetes and no effect of GABA on α-to-β cell transdifferentiation in rhesus monkeys.
Topics: Animals; Cell Transdifferentiation; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; gamm | 2019 |
[γ-aminobutyric acid fortified rice alleviated oxidative stress and pancreatic injury in type 2 diabetic mice].
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; GABA Agents; gam | 2019 |
GABA-induced vasorelaxation mediated by nitric oxide and GABAA receptor in non diabetic and streptozotocin-induced diabetic rat vessels.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Endotheli | 2013 |
Effect of pregabalin on erectile function and penile NOS expression in rats with streptozotocin-induced diabetes.
Topics: Animals; Calcium Channel Blockers; Diabetes Complications; Diabetes Mellitus, Experimental; Erectile | 2013 |
Antihyperalgesic activity of a novel synthesized analogue of lidocaine in diabetic rats.
Topics: Amines; Analgesics; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Diabetes Complications; | 2013 |
The application of support vector regression for prediction of the antiallodynic effect of drug combinations in the mouse model of streptozocin-induced diabetic neuropathy.
Topics: 4-Butyrolactone; Algorithms; Analgesics; Animals; Computer Simulation; Diabetes Mellitus, Experiment | 2013 |
Evaluation of analgesic, antioxidant, cytotoxic and metabolic effects of pregabalin for the use in neuropathic pain.
Topics: 3T3-L1 Cells; Analgesics; Animals; Antioxidants; Cell Death; Diabetes Mellitus, Experimental; Diabet | 2013 |
Lactate-induced release of GABA in the ventromedial hypothalamus contributes to counterregulatory failure in recurrent hypoglycemia and diabetes.
Topics: Animals; Bicuculline; Coumaric Acids; Diabetes Mellitus, Experimental; Diazoxide; GABA Antagonists; | 2013 |
γ-Aminobutyric acid regulates both the survival and replication of human β-cells.
Topics: Animals; Apoptosis; Baclofen; Cell Survival; Diabetes Mellitus, Experimental; GABA-A Receptor Agonis | 2013 |
Lactate and the mechanism of hypoglycemia-associated autonomic failure in diabetes.
Topics: Animals; Diabetes Mellitus, Experimental; gamma-Aminobutyric Acid; Hypoglycemia; Lactic Acid; Male; | 2013 |
GABA tea prevents cardiac fibrosis by attenuating TNF-alpha and Fas/FasL-mediated apoptosis in streptozotocin-induced diabetic rats.
Topics: Animals; Apoptosis; Diabetes Mellitus, Experimental; Fas Ligand Protein; fas Receptor; Fibrosis; gam | 2014 |
Anti-allodynic and neuroprotective effects of koumine, a Benth alkaloid, in a rat model of diabetic neuropathy.
Topics: Amines; Animals; Blood Glucose; Body Weight; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experim | 2014 |
Soluble epoxide hydrolase inhibition is antinociceptive in a mouse model of diabetic neuropathy.
Topics: Amines; Analgesics; Animals; Benzoates; Chronic Pain; Conditioning, Psychological; Cyclohexanecarbox | 2014 |
cAMP-dependent insulin modulation of synaptic inhibition in neurons of the dorsal motor nucleus of the vagus is altered in diabetic mice.
Topics: Animals; Brain Stem; Brefeldin A; Colforsin; Cyclic AMP; Diabetes Mellitus, Experimental; Diabetes M | 2014 |
GABA promotes human β-cell proliferation and modulates glucose homeostasis.
Topics: Animals; Apoptosis; Blood Glucose; Cell Proliferation; Diabetes Mellitus, Experimental; GABA Agents; | 2014 |
Type 1 diabetes alters astrocytic properties related with neurotransmitter supply, causing abnormal neuronal activities.
Topics: AMP-Activated Protein Kinases; Animals; Astrocytes; Blotting, Western; Cells, Cultured; Diabetes Mel | 2015 |
Disruption of a neural microcircuit in the rod pathway of the mammalian retina by diabetes mellitus.
Topics: Adamantane; Amacrine Cells; Animals; Calcium; Diabetes Mellitus, Experimental; Excitatory Postsynapt | 2015 |
Role of GABAB receptor and L-Arg in GABA-induced vasorelaxation in non-diabetic and streptozotocin-induced diabetic rat vessels.
Topics: Animals; Arginine; Blood Pressure; Diabetes Mellitus, Experimental; GABA-B Receptor Antagonists; gam | 2015 |
Enhanced GABA action on the substantia gelatinosa neurons of the medullary dorsal horn in the offspring of streptozotocin-injected mice.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes, Gestational; Diabetic Neuropathies; Facial Nerve | 2015 |
A streptozotocin-induced diabetic neuropathic pain model for static or dynamic mechanical allodynia and vulvodynia: validation using topical and systemic gabapentin.
Topics: Administration, Topical; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Diabetes Mellitus | 2015 |
Decreased acylcarnitine content improves insulin sensitivity in experimental mice models of insulin resistance.
Topics: Animals; Blood Glucose; Carnitine; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diet, High-Fa | 2016 |
Effect of levetiracetam versus gabapentin on peripheral neuropathy and sciatic degeneration in streptozotocin-diabetic mice: Influence on spinal microglia and astrocytes.
Topics: Amines; Animals; Astrocytes; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Diabetes | 2016 |
Influence of GABA and GABA-producing Lactobacillus brevis DPC 6108 on the development of diabetes in a streptozotocin rat model.
Topics: Animals; Antibiotics, Antineoplastic; Diabetes Mellitus, Experimental; gamma-Aminobutyric Acid; Hypo | 2016 |
Glutamatergic drive facilitates synaptic inhibition of dorsal vagal motor neurons after experimentally induced diabetes in mice.
Topics: Animals; Diabetes Mellitus, Experimental; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid | 2016 |
Diabetes negatively affects cortical and striatal GABAergic neurons: an effect that is partially counteracted by exendin-4.
Topics: Animals; Calbindin 2; Calbindins; Corpus Striatum; Diabetes Mellitus; Diabetes Mellitus, Experimenta | 2016 |
Agomelatine: a new opportunity to reduce neuropathic pain-preclinical evidence.
Topics: Acetamides; Adrenergic alpha-2 Receptor Antagonists; Amines; Animals; Antineoplastic Agents; Constri | 2017 |
GABA Signaling Stimulates β Cell Regeneration in Diabetic Mice.
Topics: Animals; Diabetes Mellitus, Experimental; gamma-Aminobutyric Acid; Insulin-Secreting Cells; Mice; Re | 2017 |
Paracrine GABA and insulin regulate pancreatic alpha cell proliferation in a mouse model of type 1 diabetes.
Topics: Animals; Blood Glucose; Cell Proliferation; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type | 2017 |
Neutrophils Infiltrate the Spinal Cord Parenchyma of Rats with Experimental Diabetic Neuropathy.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Diabetic | 2017 |
Dietary taurine supplementation prevents glial alterations in retina of diabetic rats.
Topics: Animals; Base Sequence; Diabetes Mellitus, Experimental; DNA Primers; Fluorescent Antibody Technique | 2009 |
Allodynia and hyperalgesia in diabetic rats are mediated by GABA and depletion of spinal potassium-chloride co-transporters.
Topics: Animals; Diabetes Mellitus, Experimental; gamma-Aminobutyric Acid; Hyperalgesia; Hyperesthesia; K Cl | 2008 |
FK1706, a novel non-immunosuppressive immunophilin ligand, modifies the course of painful diabetic neuropathy.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Diabetic | 2008 |
Gabapentin reverses microglial activation in the spinal cord of streptozotocin-induced diabetic rats.
Topics: Amines; Analgesics; Animals; Astrocytes; Cell Count; Cyclohexanecarboxylic Acids; Diabetes Mellitus, | 2009 |
Antinociceptive effects of chronic administration of uncompetitive NMDA receptor antagonists in a rat model of diabetic neuropathic pain.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Cyclopentanes; Diabetes Mellitus, Experime | 2009 |
Analysis of the antinociceptive interactions in two-drug combinations of gabapentin, oxcarbazepine and amitriptyline in streptozotocin-induced diabetic mice.
Topics: Administration, Oral; Amines; Amitriptyline; Analgesics; Animals; Behavior, Animal; Carbamazepine; C | 2010 |
Neuronal hyperactivity at the spinal cord and periaqueductal grey during painful diabetic neuropathy: effects of gabapentin.
Topics: Amines; Analgesics; Analysis of Variance; Animals; Cyclohexanecarboxylic Acids; Diabetes Mellitus, E | 2010 |
Diabetic thermal hyperalgesia: role of TRPV1 and CB1 receptors of periaqueductal gray.
Topics: Analgesia; Analgesics; Animals; Benzoxazines; Capsaicin; Diabetes Mellitus, Experimental; Diabetic N | 2010 |
Studies of synergy between morphine and a novel sodium channel blocker, CNSB002, in rat models of inflammatory and neuropathic pain.
Topics: Amines; Analgesics, Opioid; Animals; Carrageenan; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Ex | 2010 |
Hypoglycemia induced behavioural deficit and decreased GABA receptor, CREB expression in the cerebellum of streptozoticin induced diabetic rats.
Topics: Analysis of Variance; Animals; Cerebellum; CREB-Binding Protein; Diabetes Mellitus, Experimental; Di | 2010 |
Increased GABA(A) channel subunits expression in CD8(+) but not in CD4(+) T cells in BB rats developing diabetes compared to their congenic littermates.
Topics: Animals; Animals, Congenic; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Proliferati | 2011 |
Increased GABAergic output in the ventromedial hypothalamus contributes to impaired hypoglycemic counterregulation in diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; gamma-Aminobutyric Acid; Glucose Clamp Technique; Glutamat | 2011 |
Pharmacological interaction between gabapentin and glibenclamide in the formalin test in the diabetic rat.
Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Drug Interactions; Ga | 2010 |
Protective effects of combined therapy of gliclazide with curcumin in experimental diabetic neuropathy in rats.
Topics: Amines; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Glucose; C-Peptide; Curc | 2012 |
Acute augmentation of epoxygenated fatty acid levels rapidly reduces pain-related behavior in a rat model of type I diabetes.
Topics: Amines; Animals; Behavior, Animal; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Dia | 2012 |
Effects of white rice, brown rice and germinated brown rice on antioxidant status of type 2 diabetic rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Area Under Curve; Aspartate Aminotransferases; Blood Gl | 2012 |
Blunted endogenous GABA-mediated inhibition in the hypothalamic paraventricular nucleus of rats with streptozotocin-induced diabetes.
Topics: Animals; Bicuculline; Blood Pressure; Diabetes Mellitus, Experimental; Disease Models, Animal; GABA- | 2013 |
Orofacial sensory changes after streptozotocin-induced diabetes in rats.
Topics: Analgesics; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Facial Pain; gamma-Amin | 2013 |
Gabapentin and the neurokinin(1) receptor antagonist CI-1021 act synergistically in two rat models of neuropathic pain.
Topics: Acetates; Amines; Animals; Benzofurans; Carbamates; Cyclohexanecarboxylic Acids; Diabetes Mellitus, | 2002 |
Reduction by gabapentin of K+-evoked release of [3H]-glutamate from the caudal trigeminal nucleus of the streptozotocin-treated rat.
Topics: Acetates; Amines; Animals; Blood Glucose; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experiment | 2004 |
Novel role for gabapentin in neuroprotection of central nervous system in streptozotocine-induced diabetic rats.
Topics: Amines; Animals; Brain; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Experimental; Gabapentin; ga | 2005 |
Protective effects of gamma-aminobutyric acid in rats with streptozotocin-induced diabetes.
Topics: Animals; Blood Glucose; Diabetes Complications; Diabetes Mellitus, Experimental; gamma-Aminobutyric | 2005 |
Abnormal benzodiazepine receptor function in the depressive-like behavior of diabetic mice.
Topics: Animals; Behavior, Animal; Carbolines; Depression; Diabetes Mellitus, Experimental; Flumazenil; gamm | 2005 |
Adverse effects of gabapentin and lack of anti-allodynic efficacy of amitriptyline in the streptozotocin model of painful diabetic neuropathy.
Topics: Amines; Amitriptyline; Animals; Cognition Disorders; Cyclohexanecarboxylic Acids; Diabetes Mellitus, | 2006 |
Impaired formalin-evoked changes of spinal amino acid levels in diabetic rats.
Topics: Afferent Pathways; Amino Acids; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dis | 2006 |
Streptozotocin-induced diabetes modulates GABA receptor activity of rat retinal neurons.
Topics: Animals; Cell Shape; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; gamma-Aminob | 2007 |
Dietary taurine supplementation ameliorates diabetic retinopathy via anti-excitotoxicity of glutamate in streptozotocin-induced Sprague-Dawley rats.
Topics: Amino Acid Transport System X-AG; Animals; Blood Glucose; Blotting, Western; Body Weight; Diabetes M | 2008 |
Diabetes affects the expression of GABA and potassium chloride cotransporter in the spinal cord: a study in streptozotocin diabetic rats.
Topics: Animals; Blotting, Western; Chlorides; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disea | 2008 |
Amino acid uptake by dorsal root ganglia from streptozotocin-diabetic rats.
Topics: Animals; Axonal Transport; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Neuropathies; ga | 1984 |
Immunohistochemical studies of the GABA system in the pancreas.
Topics: 4-Aminobutyrate Transaminase; Animals; Diabetes Mellitus, Experimental; Fluorescent Antibody Techniq | 1983 |
[Alteration of gamma-aminobutyric acid in streptozotocin-induced diabetic rat retina].
Topics: Action Potentials; Animals; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Electroretinograp | 1994 |
Changes in GABA metabolism in streptozotocin-induced diabetic rat retinas.
Topics: 4-Aminobutyrate Transaminase; Amino Acids; Animals; Diabetes Mellitus, Experimental; Diabetic Retino | 1996 |
Accumulation of gamma-aminobutyric acid in diabetic rat retinal Müller cells evidenced by electron microscopic immunocytochemistry.
Topics: Animals; Antibody Specificity; Cross Reactions; Diabetes Mellitus, Experimental; Diabetic Retinopath | 1996 |
Effect of diabetes on levels and uptake of putative amino acid neurotransmitters in rat retina and retinal pigment epithelium.
Topics: Analysis of Variance; Animals; Aspartic Acid; Diabetes Mellitus, Experimental; gamma-Aminobutyric Ac | 1996 |
Microdialysis study of modification of hypothalamic neurotransmitters in streptozotocin-diabetic rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Diabetes Mellitus, Experimental; Dopamine; gamma-Aminobutyr | 1997 |
Quantitative measurement of islet glucagon response to hypoglycemia by confocal fluorescence imaging in diabetic rats: effects of phlorizin treatment.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Fluorescent Antibody Technique, Direct; gam | 1997 |
Alteration of the GABAergic neuronal system of the retina and superior colliculus in streptozotocin-induced diabetic rat.
Topics: 4-Aminobutyrate Transaminase; Animals; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Diseas | 1998 |
Gabapentin prevents hyperalgesia during the formalin test in diabetic rats.
Topics: Acetates; Amines; Analgesics; Animals; Blood Glucose; Body Weight; Cyclohexanecarboxylic Acids; Diab | 1999 |
Gabapentin and pregabalin, but not morphine and amitriptyline, block both static and dynamic components of mechanical allodynia induced by streptozocin in the rat.
Topics: Acetates; Amines; Amitriptyline; Analgesics; Animals; Cyclohexanecarboxylic Acids; Diabetes Mellitus | 1999 |
Impairment of GABA-mediated contractions of rat isolated ileum by experimental diabetes.
Topics: Acetylcholine; Animals; Diabetes Mellitus, Experimental; gamma-Aminobutyric Acid; Ileum; In Vitro Te | 1999 |
Effects of diabetes on non-adrenergic, non-cholinergic relaxation induced by GABA and electrical stimulation in the rat isolated duodenum.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Duodenum; Electric Stimulation | 1999 |
Effect of experimental diabetes on GABA-mediated inhibition of neurally induced contractions in rat isolated trachea.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Blood Glucose; Body Weight; Diabetes Mellitus, Experi | 2000 |
The effect of topical insulin on the release of excitotoxic and other amino acids from the rat cerebral cortex during streptozotocin-induced hyperglycemic ischemia.
Topics: Administration, Topical; Animals; Aspartic Acid; Blood Glucose; Brain Ischemia; Cerebral Cortex; Dia | 2000 |
Distribution of neurotransmitters and their effects on glucagon secretion from the in vitro normal and diabetic pancreatic tissues.
Topics: Acetylcholine; Animals; Biogenic Monoamines; Choline O-Acetyltransferase; Diabetes Mellitus, Experim | 2000 |
The effect of streptozotocin-induced diabetes on the release of excitotoxic and other amino acids from the ischemic rat cerebral cortex.
Topics: Acute Disease; Amino Acids; Animals; Blood Glucose; Brain Ischemia; Cerebral Cortex; Chronic Disease | 2001 |
Low taurine, gamma-aminobutyric acid and carnosine levels in plasma of diabetic pregnant rats: consequences for the offspring.
Topics: Animals; Blood Glucose; Carnosine; Diabetes Mellitus, Experimental; Female; Fetal Blood; gamma-Amino | 2001 |
Effect of endogenous beta-hydroxybutyrate on glucose metabolism in the diabetic rabbit brain: a (13)C-magnetic resonance spectroscopy study of [U-(13)C]glucose metabolites.
Topics: 3-Hydroxybutyric Acid; Alloxan; Amino Acids; Animals; Brain; Carbon Isotopes; Diabetes Mellitus, Exp | 2001 |
GABA in the endocrine pancreas: cellular localization and function in normal and diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; gamma-Aminobutyric Acid; Immunohistochemistry; Insulin; Is | 2002 |
Gamma-aminobutyric acid in peripheral tissue, with emphasis on the endocrine pancreas: presence in two species and reduction by streptozotocin.
Topics: Animals; Diabetes Mellitus, Experimental; gamma-Aminobutyric Acid; Islets of Langerhans; Male; Rats; | 1979 |
High concentration of gamma-aminobutyric acid in pancreatic beta cells.
Topics: Adenoma, Islet Cell; Animals; Blood Glucose; Diabetes Mellitus, Experimental; gamma-Aminobutyric Aci | 1979 |
Neurochemical correlates of alloxan diabetes: gamma amino butyric acid of amphibian brain.
Topics: Aminobutyrates; Animals; Anura; Aspartic Acid; Brain; Brain Stem; Diabetes Mellitus, Experimental; g | 1977 |
Changes in adenosine sensitivity in the hippocampus of rats with streptozotocin-induced diabetes.
Topics: 2-Chloroadenosine; Adenosine; Animals; Biological Transport, Active; Diabetes Mellitus, Experimental | 1992 |
Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase.
Topics: Animals; Animals, Newborn; Autoantibodies; Autoantigens; Autoimmunity; Brain; Diabetes Mellitus, Exp | 1990 |
Behavioral effects of an intrauterine or neonatal diabetic environment in the rat.
Topics: Animals; Animals, Newborn; Behavior, Animal; Blood Glucose; Body Weight; Brain Chemistry; Diabetes M | 1991 |
Decreased central GABA B receptor binding sites in diabetic rats.
Topics: Animals; Antidepressive Agents; Diabetes Mellitus, Experimental; Frontal Lobe; gamma-Aminobutyric Ac | 1988 |
Cerebral GABAergic control of arterial blood pressure and heart rate in diabetic rats.
Topics: Animals; Blood Glucose; Blood Pressure; Brain; Brain Stem; Diabetes Mellitus, Experimental; Dopamine | 1987 |