gamma-aminobutyric acid has been researched along with Alcoholic Intoxication in 38 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Alcoholic Intoxication: An acute brain syndrome which results from the excessive ingestion of ETHANOL or ALCOHOLIC BEVERAGES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with gabapentin did not significantly alter subjective and performance effects of alcohol and did not alter alcohol craving." | 2.72 | The acute effects of gabapentin in combination with alcohol in heavy drinkers. ( Bisaga, A; Evans, SM, 2006) |
| "Acute gabapentin administration was well tolerated in combination with alcohol, but did not alter the effects of alcohol." | 2.72 | The acute effects of gabapentin in combination with alcohol in heavy drinkers. ( Bisaga, A; Evans, SM, 2006) |
| "Seventeen volunteers without alcohol dependence were tested using a double-blind design with three 3-day long inpatient phases, each separated by at least a 1-week wash-out period." | 2.72 | The acute effects of gabapentin in combination with alcohol in heavy drinkers. ( Bisaga, A; Evans, SM, 2006) |
| " A single dose of ethanol initially activates the GABA system which is weakened after chronic administration because of overcompensation." | 2.36 | Ethanol and GABA. ( Kulonen, E, 1983) |
| " Sixty-nine healthy subjects (21-30 years) underwent a laboratory-based within-session cumulative oral alcohol dosing procedure, achieving a mean peak blood alcohol level of 100." | 1.39 | GABRA2 markers moderate the subjective effects of alcohol. ( Guo, X; Kranzler, HR; Li, N; McCaul, ME; Uhart, M; Wand, GS; Weerts, EM; Yan, X, 2013) |
| "Susceptibility to audiogenic seizures (AGS) is observed during ethanol withdrawal (ETX)." | 1.29 | Increased responsiveness of pontine reticular formation neurons associated with audiogenic seizure susceptibility during ethanol withdrawal. ( Faingold, CL; Riaz, A, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (39.47) | 18.7374 |
| 1990's | 10 (26.32) | 18.2507 |
| 2000's | 5 (13.16) | 29.6817 |
| 2010's | 6 (15.79) | 24.3611 |
| 2020's | 2 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Li, S | 1 |
| Zheng, Y | 1 |
| Xiao, L | 1 |
| Lan, S | 1 |
| Xiang, J | 1 |
| Liao, L | 1 |
| Lin, Y | 1 |
| Ye, Y | 1 |
| Kustova, MV | 1 |
| Prokofiev, II | 1 |
| Perfilova, VN | 1 |
| Muzyko, EA | 1 |
| Zavadskaya, VE | 1 |
| Varlamova, SV | 1 |
| Kucheryavenko, AS | 1 |
| Tyurenkov, IN | 1 |
| Vasilyeva, OS | 1 |
| Carton, L | 1 |
| Auger, F | 1 |
| Kyheng, M | 1 |
| Pétrault, M | 1 |
| Durieux, N | 1 |
| Allorge, D | 1 |
| Cottencin, O | 1 |
| Jardri, R | 1 |
| Bordet, R | 1 |
| Rolland, B | 1 |
| Lee, DW | 1 |
| Nam, YK | 1 |
| Kim, TK | 1 |
| Kim, JH | 1 |
| Kim, SY | 1 |
| Min, JW | 1 |
| Lee, JH | 1 |
| Kim, HY | 1 |
| Kim, DJ | 1 |
| Choe, BY | 1 |
| Wei, J | 1 |
| Yao, L | 1 |
| Yang, L | 1 |
| Zhao, W | 1 |
| Shi, S | 1 |
| Cai, Q | 1 |
| Chen, D | 1 |
| Li, W | 1 |
| Wang, Q | 1 |
| Wolff, N | 1 |
| Gussek, P | 1 |
| Stock, AK | 1 |
| Beste, C | 1 |
| Steffensen, SC | 1 |
| Bradley, KD | 1 |
| Hansen, DM | 1 |
| Wilcox, JD | 1 |
| Wilcox, RS | 1 |
| Allison, DW | 1 |
| Merrill, CB | 1 |
| Edwards, JG | 1 |
| Uhart, M | 1 |
| Weerts, EM | 1 |
| McCaul, ME | 1 |
| Guo, X | 1 |
| Yan, X | 1 |
| Kranzler, HR | 1 |
| Li, N | 1 |
| Wand, GS | 1 |
| HAEKKINEN, HM | 1 |
| KULONEN, E | 3 |
| Carta, M | 1 |
| Mameli, M | 2 |
| Valenzuela, CF | 1 |
| Bisaga, A | 1 |
| Evans, SM | 1 |
| Roberto, M | 1 |
| Treistman, SN | 1 |
| Pietrzykowski, AZ | 1 |
| Weiner, J | 1 |
| Galindo, R | 1 |
| Valenzuela, F | 1 |
| Zhu, PJ | 2 |
| Lovinger, D | 1 |
| Zhang, TA | 1 |
| Hendricson, AH | 1 |
| Morrisett, R | 1 |
| Siggins, GR | 1 |
| Lovinger, DM | 1 |
| Bazil, CW | 1 |
| Battista, J | 1 |
| Basner, RC | 1 |
| Kiianmaa, K | 1 |
| Borisenko, SA | 1 |
| Tolmacheva, NS | 1 |
| Burov, IuV | 1 |
| Blinkova, NF | 1 |
| Blagova, OE | 2 |
| Budantsev, AY | 1 |
| Sytinsky, IA | 2 |
| Lajtha, A | 1 |
| Edmonds, HL | 1 |
| Sylvester, DM | 1 |
| Bellin, SI | 1 |
| Nikitina, ZS | 1 |
| Erickson, CK | 1 |
| Sanna, E | 1 |
| Harris, RA | 3 |
| Peoples, RW | 1 |
| Weight, FF | 1 |
| Dahchour, A | 1 |
| Quertemont, E | 1 |
| De Witte, P | 2 |
| Faingold, CL | 1 |
| Riaz, A | 1 |
| Minetti, A | 1 |
| Arolfo, MP | 1 |
| Virgolini, MB | 1 |
| Brioni, JD | 1 |
| Fulginiti, S | 1 |
| Tomkins, DM | 1 |
| Sellers, EM | 1 |
| Fletcher, PJ | 1 |
| Liu, Y | 1 |
| Deitrich, RA | 1 |
| Hakkinen, HM | 1 |
| Guzikov, BM | 1 |
| Gomanko, MV | 1 |
| Eremin, VP | 1 |
| Konovalova, NN | 1 |
| Gewiss, M | 1 |
| Heidbreder, C | 1 |
| Opsomer, L | 1 |
| Durbin, P | 1 |
| Little, HJ | 1 |
| Moss, HB | 1 |
| Yao, JK | 1 |
| Burns, M | 1 |
| Maddock, J | 1 |
| Tarter, RE | 1 |
| Allan, AM | 2 |
| Pellegrini-Giampietro, DE | 1 |
| Moroni, F | 1 |
| Pistelli, A | 1 |
| Palmerani, B | 1 |
| Zorn, AM | 1 |
| Peruzzi, S | 1 |
| Caramelli, L | 1 |
| Botti, P | 1 |
| Valenza, T | 1 |
| Antonini, M | 1 |
| Hauser, WA | 1 |
| Ng, SK | 1 |
| Brust, JC | 1 |
| Johnson, R | 1 |
| Coffman, JA | 1 |
| Petty, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The BrainDrugs-Epilepsy Study: A Prospective Open-label Cohort Precision Medicine Study in Epilepsy[NCT05450822] | 550 participants (Anticipated) | Observational | 2022-02-18 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for gamma-aminobutyric acid and Alcoholic Intoxication
| Article | Year |
|---|---|
[Alcohol and neurotransmitters].
Topics: Alcoholic Intoxication; Alcoholism; Drug Tolerance; Ethanol; gamma-Aminobutyric Acid; Humans; Nerve | 1982 |
Ethanol and GABA.
Topics: 4-Aminobutyrate Transaminase; Alcoholic Intoxication; Alcoholism; Animals; Benzodiazepines; Brain; C | 1983 |
Recent developments in alcoholism:neuronal ion channels.
Topics: Alcohol Drinking; Alcoholic Intoxication; Alcoholism; Animals; Brain; gamma-Aminobutyric Acid; Gluta | 1993 |
Mechanisms that may underlie the behavioural effects of ethanol.
Topics: Alcoholic Intoxication; Animals; Aspartic Acid; Behavior; Behavior, Animal; Calcium; Calcium Channel | 1991 |
Involvement of neuronal chloride channels in ethanol intoxication, tolerance, and dependence.
Topics: Alcoholic Intoxication; Alcoholism; Animals; Chlorides; gamma-Aminobutyric Acid; Humans; Ion Channel | 1987 |
Alcohol intoxication: ion channels and genetics.
Topics: Alcoholic Intoxication; Animals; Chloride Channels; Chlorides; Electrophysiology; gamma-Aminobutyric | 1989 |
Alcohol and fits.
Topics: Adolescent; Adult; Aged; Alcoholic Intoxication; Alcoholism; Anticonvulsants; Brain Chemistry; Brain | 1985 |
3 trials available for gamma-aminobutyric acid and Alcoholic Intoxication
| Article | Year |
|---|---|
The acute effects of gabapentin in combination with alcohol in heavy drinkers.
Topics: Adult; Alcoholic Intoxication; Alcoholism; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dos | 2006 |
Gabapentin improves sleep in the presence of alcohol.
Topics: Adult; Alcoholic Intoxication; Amines; Anti-Anxiety Agents; Cross-Over Studies; Cyclohexanecarboxyli | 2005 |
Plasma GABA-like activity in response to ethanol challenge in men at high risk for alcoholism.
Topics: Adult; Alcohol Drinking; Alcoholic Intoxication; Alcoholism; Breath Tests; Ethanol; gamma-Aminobutyr | 1990 |
28 other studies available for gamma-aminobutyric acid and Alcoholic Intoxication
| Article | Year |
|---|---|
Aldehyde dehydrogenase 2-associated changes in pharmacokinetics, locomotor function and peripheral glutamic acid and gamma-aminobutyric acid levels during acute alcohol intoxication in male mice.
Topics: Acetaldehyde; Alcoholic Intoxication; Aldehyde Dehydrogenase, Mitochondrial; Animals; Blood Alcohol | 2022 |
The role of iNOS inhibition in the mechanism of the cardioprotective effect of new GABA and glutamic acid derivatives in the model of acute alcoholic myocardial injury in rats.
Topics: Alcoholic Intoxication; Animals; Cardiotonic Agents; gamma-Aminobutyric Acid; Glutamic Acid; Heart; | 2023 |
Dose-dependent metabolite changes after ethanol intoxication in rat prefrontal cortex using in vivo magnetic resonance spectroscopy.
Topics: Alcoholic Intoxication; Animals; Choline; Creatine; Dose-Response Relationship, Drug; Ethanol; gamma | 2019 |
Dose-dependent influence of short-term intermittent ethanol intoxication on cerebral neurochemical changes in rats detected by ex vivo proton nuclear magnetic resonance spectroscopy.
Topics: Alanine; Alcoholic Intoxication; Animals; Aspartic Acid; Body Weight; Central Nervous System Depress | 2014 |
Alteration of glutamate/GABA balance during acute alcohol intoxication in rats: effect of Xingnaojing injection.
Topics: Alcoholic Intoxication; Animals; Drugs, Chinese Herbal; Ethanol; gamma-Aminobutyric Acid; Glutamic A | 2015 |
Effects of high-dose ethanol intoxication and hangover on cognitive flexibility.
Topics: Adolescent; Adult; Alcoholic Intoxication; Attention; Brain; Breath Tests; Cognition; Electroencepha | 2018 |
The role of connexin-36 gap junctions in alcohol intoxication and consumption.
Topics: Action Potentials; Alcohol Drinking; Alcoholic Intoxication; Animals; Central Nervous System Depress | 2011 |
GABRA2 markers moderate the subjective effects of alcohol.
Topics: Adult; Alcoholic Intoxication; Alcoholism; Alleles; Chromosomes, Human, Pair 4; Cohort Studies; Dose | 2013 |
COMPARISON OF VARIOUS METHODS FOR THE DETERMINATION OF GAMMA-AMINOBUTYRIC ACID AND OTHER AMINO ACIDS IN RAT BRAIN WITH REFERENCE TO ETHANOL INTOXICATION.
Topics: Alcoholic Intoxication; Amino Acids; Aminobutyrates; Brain; Ethanol; gamma-Aminobutyric Acid; Neuroc | 1963 |
Alcohol enhances GABAergic transmission to cerebellar granule cells via an increase in Golgi cell excitability.
Topics: Alcoholic Intoxication; Animals; Cerebellum; Dose-Response Relationship, Drug; Ethanol; Excitatory A | 2004 |
Actions of acute and chronic ethanol on presynaptic terminals.
Topics: Alcoholic Intoxication; Alcoholism; Animals; Brain; gamma-Aminobutyric Acid; Glutamic Acid; Humans; | 2006 |
Ethanol potentiates GABAergic synaptic transmission in a postsynaptic neuron/synaptic bouton preparation from basolateral amygdala.
Topics: Action Potentials; Alcoholic Intoxication; Amygdala; Animals; Central Nervous System Depressants; El | 2006 |
[Permeability of the blood-brain barrier to 3H-GABA during alcoholic intoxication].
Topics: Acetaldehyde; Alcoholic Intoxication; Animals; Blood-Brain Barrier; Brain; Caudate Nucleus; Cerebral | 1982 |
Changes of neurochemical and electrophysiological indices of rat brain under ethanol intoxication.
Topics: Alcohol Withdrawal Delirium; Alcoholic Intoxication; Animals; Brain; Catecholamines; Dopamine; Evoke | 1982 |
[Gamma-aminobutyric acid system and bioelectric activity of the brain of rats during alcoholic intoxication].
Topics: 4-Aminobutyrate Transaminase; Alcoholic Intoxication; Animals; Brain Chemistry; Electroencephalograp | 1980 |
Requirements for an ideal alcohol antagonist.
Topics: Alcoholic Intoxication; Animals; Caffeine; Cats; Dextroamphetamine; Disease Models, Animal; Dogs; Et | 1980 |
Cutoff in potency implicates alcohol inhibition of N-methyl-D-aspartate receptors in alcohol intoxication.
Topics: Alcoholic Intoxication; Alcohols; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Fetus; | 1995 |
Acute ethanol increases taurine but neither glutamate nor GABA in the nucleus accumbens of male rats: a microdialysis study.
Topics: Alcoholic Intoxication; Animals; Chromatography, High Pressure Liquid; Ethanol; gamma-Aminobutyric A | 1994 |
Increased responsiveness of pontine reticular formation neurons associated with audiogenic seizure susceptibility during ethanol withdrawal.
Topics: Acoustic Stimulation; Alcoholic Intoxication; Alcoholism; Animals; Ethanol; gamma-Aminobutyric Acid; | 1994 |
Spatial learning in rats exposed to acute ethanol intoxication on gestational day 8.
Topics: Alcoholic Intoxication; Animals; Female; gamma-Aminobutyric Acid; Hippocampus; Kinetics; Male; Maze | 1996 |
Effect of dorsal raphe injections of the GABAA agonist, muscimol, on ethanol intake and measures of intoxication in Wistar rats.
Topics: Alcohol Drinking; Alcoholic Intoxication; Animals; Conditioning, Operant; Drinking Behavior; Ethanol | 1994 |
Role of GABA in the actions of ethanol in rats selectively bred for ethanol sensitivity.
Topics: Alcoholic Intoxication; Animals; Behavior, Animal; Central Nervous System Depressants; Chlorides; Et | 1998 |
Ethanol intoxication and gamma-aminobutyric acid.
Topics: Alcoholic Intoxication; Aminobutyrates; Aminooxyacetic Acid; Animals; Bicuculline; Brain; Ethanol; g | 1976 |
The gamma-aminobutyric acid (GABA) system in brain during acute and chronic ethanol intoxication.
Topics: 1-Propanol; 4-Aminobutyrate Transaminase; Acute Disease; Alcoholic Intoxication; Aminobutyrates; Ani | 1975 |
Acamprosate and diazepam differentially modulate alcohol-induced behavioural and cortical alterations in rats following chronic inhalation of ethanol vapour.
Topics: Acamprosate; Administration, Inhalation; Alcohol Drinking; Alcoholic Intoxication; Alcoholism; Anima | 1991 |
Pyrrolidone carboxylic acid in acute and chronic alcoholism. Preclinical and clinical studies.
Topics: Alcoholic Intoxication; Alcoholism; Animals; Ethanol; Female; gamma-Aminobutyric Acid; Guinea Pigs; | 1989 |
Alcohol, seizures, and epilepsy.
Topics: Alcoholic Intoxication; Alcoholism; Animals; Brain Diseases; Epilepsy; Ethanol; gamma-Aminobutyric A | 1988 |
Plasma GABA levels in chronic alcoholics.
Topics: Adult; Alcoholic Intoxication; Alcoholism; Brain Chemistry; Ethanol; gamma-Aminobutyric Acid; Humans | 1985 |