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gamma-aminobutyric acid and Alcohol Withdrawal Seizures

gamma-aminobutyric acid has been researched along with Alcohol Withdrawal Seizures in 7 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Alcohol Withdrawal Seizures: A condition where seizures occur in association with ethanol abuse (ALCOHOLISM) without other identifiable causes. Seizures usually occur within the first 6-48 hours after the cessation of alcohol intake, but may occur during periods of alcohol intoxication. Single generalized tonic-clonic motor seizures are the most common subtype, however, STATUS EPILEPTICUS may occur. (Adams et al., Principles of Neurology, 6th ed, p1174)

Research Excerpts

ExcerptRelevanceReference
" Most of the studies evaluating the efficacy of GHB in the treatment of AWS use a dosage of 50 mg/kg divided in three or four administrations per day."6.52Clinical applications of sodium oxybate (GHB): from narcolepsy to alcohol withdrawal syndrome. ( Busardò, FP; Kyriakou, C; Marinelli, E; Napoletano, S; Zaami, S, 2015)
" Most of the studies evaluating the efficacy of GHB in the treatment of AWS use a dosage of 50 mg/kg divided in three or four administrations per day."2.52Clinical applications of sodium oxybate (GHB): from narcolepsy to alcohol withdrawal syndrome. ( Busardò, FP; Kyriakou, C; Marinelli, E; Napoletano, S; Zaami, S, 2015)
"Problematic compounds may cause seizures either acutely or on withdrawal: Their use may reduce effectiveness of antiepileptic drugs, or may simply promote and enhance chaotic lifestyles."2.48Alcohol and drugs in epilepsy: pathophysiology, presentation, possibilities, and prevention. ( Borland, W; Leach, JP; Mohanraj, R, 2012)
"Gabapentin was safe and well tolerated."1.32A study of gabapentin in the treatment of tonic-clonic seizures of alcohol withdrawal syndrome. ( Kundurović, Z; Rustembegovic, A; Sofic, E; Tahirović, I, 2004)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (71.43)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Busardò, FP1
Kyriakou, C1
Napoletano, S1
Marinelli, E1
Zaami, S1
Leach, JP1
Mohanraj, R1
Borland, W1
Faingold, CL1
Voris, J1
Smith, NL1
Rao, SM1
Thorne, DL1
Flowers, QJ1
Rustembegovic, A1
Sofic, E1
Tahirović, I1
Kundurović, Z1
Coutin-Churchman, P1
Moreno, R1
Añez, Y1
Vergara, F1
Evans, MS1
Li, Y1
Faingold, C1

Reviews

3 reviews available for gamma-aminobutyric acid and Alcohol Withdrawal Seizures

ArticleYear
Clinical applications of sodium oxybate (GHB): from narcolepsy to alcohol withdrawal syndrome.
    European review for medical and pharmacological sciences, 2015, Volume: 19, Issue:23

    Topics: Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Female; gamma-Aminobutyric Acid; Humans; I

2015
Alcohol and drugs in epilepsy: pathophysiology, presentation, possibilities, and prevention.
    Epilepsia, 2012, Volume: 53 Suppl 4

    Topics: Alcohol Drinking; Alcohol Withdrawal Seizures; Alcoholism; Amphetamine-Related Disorders; Benzodiaze

2012
Role of GABA abnormalities in the inferior colliculus pathophysiology - audiogenic seizures.
    Hearing research, 2002, Volume: 168, Issue:1-2

    Topics: Acoustic Stimulation; Alcohol Withdrawal Seizures; Animals; Epilepsy, Reflex; GABA Antagonists; gamm

2002

Other Studies

4 other studies available for gamma-aminobutyric acid and Alcohol Withdrawal Seizures

ArticleYear
Gabapentin for the treatment of ethanol withdrawal.
    Substance abuse, 2003, Volume: 24, Issue:2

    Topics: Acetates; Adult; Alcohol Withdrawal Seizures; Amines; Anticonvulsants; Benzodiazepines; Central Nerv

2003
A study of gabapentin in the treatment of tonic-clonic seizures of alcohol withdrawal syndrome.
    Medicinski arhiv, 2004, Volume: 58, Issue:1

    Topics: Acetates; Alcohol Withdrawal Seizures; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female;

2004
Clinical correlates of quantitative EEG alterations in alcoholic patients.
    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2006, Volume: 117, Issue:4

    Topics: Adult; Age Factors; Aged; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders, Nervous System; Al

2006
Inferior colliculus intracellular response abnormalities in vitro associated with susceptibility to ethanol withdrawal seizures.
    Alcoholism, clinical and experimental research, 2000, Volume: 24, Issue:8

    Topics: Action Potentials; Alcohol Withdrawal Seizures; Animals; Bicuculline; Electric Impedance; Ethanol; G

2000