gamma-aminobutyric acid has been researched along with Alcohol Withdrawal Associated Autonomic Hyperactivity in 21 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Most of the studies evaluating the efficacy of GHB in the treatment of AWS use a dosage of 50 mg/kg divided in three or four administrations per day." | 6.52 | Clinical applications of sodium oxybate (GHB): from narcolepsy to alcohol withdrawal syndrome. ( Busardò, FP; Kyriakou, C; Marinelli, E; Napoletano, S; Zaami, S, 2015) |
| "Gabapentin was associated with significantly greater reductions than placebo on several measures of subjective craving for alcohol as well as for affectively evoked craving." | 2.74 | Proof-of-concept human laboratory study for protracted abstinence in alcohol dependence: effects of gabapentin. ( Drobes, DJ; Light, JM; Mason, BJ; Williams, LD, 2009) |
| " Most of the studies evaluating the efficacy of GHB in the treatment of AWS use a dosage of 50 mg/kg divided in three or four administrations per day." | 2.52 | Clinical applications of sodium oxybate (GHB): from narcolepsy to alcohol withdrawal syndrome. ( Busardò, FP; Kyriakou, C; Marinelli, E; Napoletano, S; Zaami, S, 2015) |
| "The effect of alcohol dependence induced by ethanol inhalation on GABA-dependent 36Cl- influx into membrane vesicles prepared from the mouse brain has been examined." | 1.28 | Functional alterations in cerebral GABAA receptor complex associated with formation of alcohol dependence: analysis using GABA-dependent 36Cl- influx into neuronal membrane vesicles. ( Kuriyama, K; Ueha, T, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (19.05) | 18.7374 |
| 1990's | 11 (52.38) | 18.2507 |
| 2000's | 4 (19.05) | 29.6817 |
| 2010's | 2 (9.52) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Busardò, FP | 1 |
| Kyriakou, C | 1 |
| Napoletano, S | 1 |
| Marinelli, E | 1 |
| Zaami, S | 1 |
| Mason, BJ | 1 |
| Light, JM | 1 |
| Williams, LD | 1 |
| Drobes, DJ | 1 |
| Martinotti, G | 1 |
| Di Nicola, M | 1 |
| Tedeschi, D | 1 |
| Andreoli, S | 1 |
| Reina, D | 1 |
| Pomponi, M | 1 |
| Mazza, M | 1 |
| Romanelli, R | 1 |
| Moroni, N | 1 |
| De Filippis, R | 1 |
| Di Giannantonio, M | 1 |
| Pozzi, G | 1 |
| Bria, P | 1 |
| Janiri, L | 2 |
| Diana, M | 1 |
| Brodie, M | 1 |
| Muntoni, A | 1 |
| Puddu, MC | 1 |
| Pillolla, G | 1 |
| Steffensen, S | 1 |
| Spiga, S | 1 |
| Little, HJ | 1 |
| Schmidt, LG | 1 |
| Bleich, S | 1 |
| Boening, J | 1 |
| Buehringer, G | 1 |
| Kornhuber, J | 1 |
| Weijers, HG | 1 |
| Wiesbeck, GA | 1 |
| Wolfgramm, J | 1 |
| Havemann-Reinecke, U | 1 |
| Pittenger, C | 1 |
| Desan, PH | 1 |
| Hunt, WA | 1 |
| Emrich, HM | 1 |
| von Zerssen, D | 1 |
| Kissling, W | 1 |
| Möller, HJ | 1 |
| Windorfer, A | 1 |
| Chan, AW | 1 |
| Schanley, DL | 1 |
| Leong, FW | 1 |
| Casbeer, D | 1 |
| Blagova, OE | 1 |
| Budantsev, AY | 1 |
| Sytinsky, IA | 1 |
| Lajtha, A | 1 |
| Aliyev, NA | 1 |
| Aliyev, ZN | 1 |
| Aliguliyev, AR | 1 |
| Gobbi, G | 1 |
| Persico, AM | 1 |
| Santarelli, M | 1 |
| Minciacchi, D | 1 |
| Tempesta, E | 1 |
| Fifková, E | 1 |
| Eason, H | 1 |
| Bueltmann, K | 1 |
| Lanman, J | 1 |
| McCown, TJ | 1 |
| Breese, GR | 1 |
| Gonzalez, LP | 1 |
| Stuppaeck, CH | 1 |
| Deisenhammer, EA | 1 |
| Kurz, M | 1 |
| Whitworth, AB | 1 |
| Hinterhuber, H | 1 |
| Adinoff, B | 1 |
| Kramer, GL | 1 |
| Petty, F | 1 |
| Riihioja, P | 1 |
| Jaatinen, P | 1 |
| Oksanen, H | 1 |
| Haapalinna, A | 1 |
| Heinonen, E | 1 |
| Hervonen, A | 1 |
| Myrick, H | 1 |
| Malcolm, R | 1 |
| Brady, KT | 1 |
| Peris, J | 1 |
| Coleman-Hardee, M | 1 |
| Burry, J | 1 |
| Pecins-Thompson, M | 1 |
| Kuriyama, K | 1 |
| Ueha, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacogenetic Treatment With Anti-Glutaminergic Agents for Comorbid PTSD & AUD[NCT02884908] | Phase 3 | 252 participants (Anticipated) | Interventional | 2016-09-30 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for gamma-aminobutyric acid and Alcohol Withdrawal Associated Autonomic Hyperactivity
| Article | Year |
|---|---|
Clinical applications of sodium oxybate (GHB): from narcolepsy to alcohol withdrawal syndrome.
Topics: Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Female; gamma-Aminobutyric Acid; Humans; I | 2015 |
The effect of ethanol on GABAergic transmission.
Topics: Alcohol Withdrawal Delirium; Alcoholism; Animals; Anti-Anxiety Agents; Benzodiazepines; Brain; Dose- | 1983 |
4 trials available for gamma-aminobutyric acid and Alcohol Withdrawal Associated Autonomic Hyperactivity
| Article | Year |
|---|---|
Proof-of-concept human laboratory study for protracted abstinence in alcohol dependence: effects of gabapentin.
Topics: Adult; Affect; Alcohol Deterrents; Alcohol Withdrawal Delirium; Alcoholism; Amines; Arousal; Cues; C | 2009 |
Pregabalin versus naltrexone in alcohol dependence: a randomised, double-blind, comparison trial.
Topics: Adult; Alcohol Withdrawal Delirium; Alcohol-Related Disorders; Anticonvulsants; Anxiety; Calcium Cha | 2010 |
Effect of sodium valproate on mania. The GABA-hypothesis of affective disorders.
Topics: Adolescent; Adult; Affective Disorders, Psychotic; Alcohol Withdrawal Delirium; Bipolar Disorder; Cl | 1980 |
Gabapentin treatment of alcohol withdrawal.
Topics: Acetates; Adult; Alcohol Withdrawal Delirium; Alcoholism; Ambulatory Care; Amines; Anticonvulsants; | 1998 |
15 other studies available for gamma-aminobutyric acid and Alcohol Withdrawal Associated Autonomic Hyperactivity
| Article | Year |
|---|---|
Enduring effects of chronic ethanol in the CNS: basis for alcoholism.
Topics: Alcohol Withdrawal Delirium; Alcohol-Induced Disorders, Nervous System; Animals; Brain Damage, Chron | 2003 |
Advances in alcoholism research in Germany.
Topics: Alcohol Withdrawal Delirium; Alcoholism; Animals; Brain; Comorbidity; Dopamine; Early Diagnosis; gam | 2005 |
Gabapentin abuse, and delirium tremens upon gabapentin withdrawal.
Topics: Adult; Alcohol Withdrawal Delirium; Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Drug A | 2007 |
Dissociation of tolerance and physical dependence after ethanol/chlordiazepoxide intake.
Topics: Alcohol Withdrawal Delirium; Animals; Body Temperature Regulation; Brain; Chlordiazepoxide; Drug Tol | 1982 |
Changes of neurochemical and electrophysiological indices of rat brain under ethanol intoxication.
Topics: Alcohol Withdrawal Delirium; Alcoholic Intoxication; Animals; Brain; Catecholamines; Dopamine; Evoke | 1982 |
Amino acid neurotransmitters in alcohol withdrawal.
Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Amino Acids; Aspartic Acid; gamma-Aminobutyric Acid; | 1994 |
Alterations of neocortical neuronal responses to acetylcholine and GABA in rats born to alcohol-dependent mothers.
Topics: Acetylcholine; Alcohol Withdrawal Delirium; Animals; Animals, Newborn; Atropine; Bicuculline; Cerebr | 1994 |
Changes in GABAergic and non-GABAergic synapses during chronic ethanol exposure and withdrawal in the dentate fascia of LS and SS mice.
Topics: Alcohol Withdrawal Delirium; Alcoholism; Animals; Axons; Dendrites; Ethanol; gamma-Aminobutyric Acid | 1994 |
A potential contribution to ethanol withdrawal kindling: reduced GABA function in the inferior collicular cortex.
Topics: Alcohol Withdrawal Delirium; Animals; Bicuculline; Dose-Response Relationship, Drug; Ethanol; gamma- | 1993 |
Sensitivity to strychnine seizures is unaltered during ethanol withdrawal.
Topics: Alcohol Withdrawal Delirium; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Ethanol; ga | 1993 |
The irreversible gamma-aminobutyrate transaminase inhibitor vigabatrin in the treatment of the alcohol withdrawal syndrome.
Topics: 4-Aminobutyrate Transaminase; Adult; Alcohol Withdrawal Delirium; Alcoholism; Anticonvulsants; Elect | 1996 |
Levels of gamma-aminobutyric acid in cerebrospinal fluid and plasma during alcohol withdrawal.
Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Blood Pressure; Blood-Brain Barrier; gamma-Aminobuty | 1995 |
Dexmedetomidine, diazepam, and propranolol in the treatment of ethanol withdrawal symptoms in the rat.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Alcohol Withdrawal Delirium; Animals; Anti-A | 1997 |
Selective changes in GABAergic transmission in substantia nigra and superior colliculus caused by ethanol and ethanol withdrawal.
Topics: Alcohol Withdrawal Delirium; Alcoholism; Animals; Autoradiography; Brain Mapping; Culture Techniques | 1992 |
Functional alterations in cerebral GABAA receptor complex associated with formation of alcohol dependence: analysis using GABA-dependent 36Cl- influx into neuronal membrane vesicles.
Topics: Administration, Inhalation; Alcohol Withdrawal Delirium; Alcoholism; Animals; Brain; Bridged Bicyclo | 1992 |