gamma-aminobutyric acid has been researched along with Aggression in 132 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Aggression: Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To provide a qualitative, systematic update and review of the pharmacology, pharmacokinetics, efficacy in mood disorders, adverse effects, and costs of lamotrigine." | 8.81 | Lamotrigine update and its use in mood disorders. ( Hurley, SC, 2002) |
| "The possible role of GABA in human aggression was evaluated by administering gabapentin to subjects with and without a history of conduct disorder and comparing the effects on laboratory measures of aggression and escape." | 7.72 | Acute effects of gabapentin on laboratory measures of aggressive and escape responses of adult parolees with and without a history of conduct disorder. ( Cherek, DR; Lane, SD; Pietras, CJ; Tcheremissine, OV, 2004) |
| "Gabapentin produced similar bitonic effects upon aggressive and escape responses in subjects with and without a history of childhood conduct disorder." | 7.72 | Acute effects of gabapentin on laboratory measures of aggressive and escape responses of adult parolees with and without a history of conduct disorder. ( Cherek, DR; Lane, SD; Pietras, CJ; Tcheremissine, OV, 2004) |
| "In a 24-patient case series from retrospective chart review, the authors examined the use of gabapentin for the treatment of aggressive and agitated behaviors in nursing home patients with a DSM-IV diagnosis of dementia." | 7.70 | A retrospective chart review of gabapentin for the treatment of aggressive and agitated behavior in patients with dementias. ( Hawkins, JW; Peyser, CE; Sheikh, JI; Tinklenberg, JR; Yesavage, JA, 2000) |
| "Gabapentin (GBP) is a new antiepileptic drug (AED) approved for adjunctive treatment of complex partial seizures with or without seizures secondarily generalization in adults." | 7.69 | Gabapentin associated with aggressive behavior in pediatric patients with seizures. ( Lo, W; Nahata, MC; Tallian, KB; Tsao, CY, 1996) |
| "The effects of gamma aminobutyric acid (GABA), baclofen, and clonidine was studied on footshock-induced aggression in mice." | 7.67 | GABAergic agents and clonidine attenuate footshock-induced aggression in mice. ( Aley, KO; Kulkarni, SK, 1989) |
| " A slow upward dose titration is recommended to reduce the incidence of serious rash, but this may delay the attainment of adequate dosage for 6 weeks." | 6.41 | Lamotrigine update and its use in mood disorders. ( Hurley, SC, 2002) |
| "Lamotrigine has positive effects on cognitive function, but occasionally produces insomnia." | 6.41 | Lamotrigine update and its use in mood disorders. ( Hurley, SC, 2002) |
| "Spontaneous recurrent seizures were monitored with Racine's seizure severity scale." | 5.32 | Human neural stem cell transplantation reduces spontaneous recurrent seizures following pilocarpine-induced status epilepticus in adult rats. ( Chu, K; Jeon, D; Jeong, SW; Jung, KH; Kim, J; Kim, M; Kim, SU; Lee, SK; Lee, ST; Roh, JK; Shin, HS, 2004) |
| "Gabapentin (GBP) is a new antiepileptic drug (AED) approved for adjunctive treatment of complex partial seizures with or without seizures secondarily generalization in adults." | 5.29 | Gabapentin associated with aggressive behavior in pediatric patients with seizures. ( Lo, W; Nahata, MC; Tallian, KB; Tsao, CY, 1996) |
| "To review and summarize the currently available data on the use of anticonvulsant mood stabilizers (carbamazepine, valproic acid, gabapentin, lamotrigine, topiramate) in the treatment of behavioral and psychological symptoms of dementia (BPSD); to determine whether these medications can be recommended for routine clinical use." | 4.84 | Anticonvulsants for the treatment of behavioral and psychological symptoms of dementia: a literature review. ( Konovalov, S; Muralee, S; Tampi, RR, 2008) |
| "To provide a qualitative, systematic update and review of the pharmacology, pharmacokinetics, efficacy in mood disorders, adverse effects, and costs of lamotrigine." | 4.81 | Lamotrigine update and its use in mood disorders. ( Hurley, SC, 2002) |
| "The objective of this study was to assess the relationship between cerebrospinal fluid concentrations of the neurotransmitter gamma-aminobutyric acid (GABA) and measures of impulsivity and related behaviors (aggression and suicidality) in healthy volunteer and personality disordered subjects." | 3.75 | Cerebrospinal fluid GABA concentration: relationship with impulsivity and history of suicidal behavior, but not aggression, in human subjects. ( Coccaro, EF; Lee, R; Petty, F, 2009) |
| "The possible role of GABA in human aggression was evaluated by administering gabapentin to subjects with and without a history of conduct disorder and comparing the effects on laboratory measures of aggression and escape." | 3.72 | Acute effects of gabapentin on laboratory measures of aggressive and escape responses of adult parolees with and without a history of conduct disorder. ( Cherek, DR; Lane, SD; Pietras, CJ; Tcheremissine, OV, 2004) |
| "Gabapentin produced similar bitonic effects upon aggressive and escape responses in subjects with and without a history of childhood conduct disorder." | 3.72 | Acute effects of gabapentin on laboratory measures of aggressive and escape responses of adult parolees with and without a history of conduct disorder. ( Cherek, DR; Lane, SD; Pietras, CJ; Tcheremissine, OV, 2004) |
| "In a 24-patient case series from retrospective chart review, the authors examined the use of gabapentin for the treatment of aggressive and agitated behaviors in nursing home patients with a DSM-IV diagnosis of dementia." | 3.70 | A retrospective chart review of gabapentin for the treatment of aggressive and agitated behavior in patients with dementias. ( Hawkins, JW; Peyser, CE; Sheikh, JI; Tinklenberg, JR; Yesavage, JA, 2000) |
| "Gabapentin (GBP) is a new antiepileptic drug (AED) approved for adjunctive treatment of complex partial seizures with or without seizures secondarily generalization in adults." | 3.69 | Gabapentin associated with aggressive behavior in pediatric patients with seizures. ( Lo, W; Nahata, MC; Tallian, KB; Tsao, CY, 1996) |
| "The effects of gamma aminobutyric acid (GABA), baclofen, and clonidine was studied on footshock-induced aggression in mice." | 3.67 | GABAergic agents and clonidine attenuate footshock-induced aggression in mice. ( Aley, KO; Kulkarni, SK, 1989) |
| "Experiments on isolated mice (CC57W males) have demonstrated that GABA antagonists (bicuculline, picrotoxin, thiosemicarbazide) increase the desocializing effects of isolation (enhance aggression and reduce intraspecies sociability), while GABA-positive drugs (muscimol, gamma-acetylenic GABA) within a certain dosage range diminish aggression and favour a temporary recovery of sociability." | 3.66 | [GABA-ergic correlates of aggression and intraspecies sociability of mice subjected to isolation]. ( Poshivalov, VP, 1981) |
| "Lamotrigine has positive effects on cognitive function, but occasionally produces insomnia." | 2.41 | Lamotrigine update and its use in mood disorders. ( Hurley, SC, 2002) |
| " A slow upward dose titration is recommended to reduce the incidence of serious rash, but this may delay the attainment of adequate dosage for 6 weeks." | 2.41 | Lamotrigine update and its use in mood disorders. ( Hurley, SC, 2002) |
| "Aggression is known to be regulated by pheromonal information in many species." | 1.72 | GABA transmission from mAL interneurons regulates aggression in ( Chan, YB; Kravitz, EA; Palavicino-Maggio, CB; Sengupta, S, 2022) |
| " Results of the study indicate that 1) Early SIS could be considered as an animal model of psychosocial stress to investigate the psychiatric comorbidities in seizure disorders, 2) Chronic administration of low dose GBP prevented the shaping of behavioral abnormalities in adulthood, 3) Chronic administration of low dose GBP produced no negative behavioral effects in socially conditioned mice suggesting the safety of the drug, 4) Gabapentin at low doses may be considered as an agent for management of epilepsy in individuals with psychiatric comorbidities." | 1.46 | Protective effects of gabapentin against the seizure susceptibility and comorbid behavioral abnormalities in the early socially isolated mice. ( Amini-Khoei, H; Amiri, S; Ghazi-Khansari, M; Haj-Mirzaian, A; Mohsenzadeh, A; Olson, CO; Rahimi-Balaei, M; Rastegar, M; Razmi, A; Shirzadian, A; Zarrindast, MR, 2017) |
| "Long-term untreated epilepsy may expose to accident proneness and further psychiatric deterioration." | 1.39 | Epilepsy and brain injury: a case report of a dramatic neuropsychiatric vicious circle. ( Angeletti, G; Carbonetti, P; Del Casale, A; Fensore, C; Ferracuti, S; Girardi, P; Kotzalidis, GD; Lazanio, S; Muzi, A; Rapinesi, C; Savoja, V; Scatena, P; Serata, D; Tatarelli, R, 2013) |
| "Early treatment of epilepsy is warranted to avoid possible severe consequences." | 1.39 | Epilepsy and brain injury: a case report of a dramatic neuropsychiatric vicious circle. ( Angeletti, G; Carbonetti, P; Del Casale, A; Fensore, C; Ferracuti, S; Girardi, P; Kotzalidis, GD; Lazanio, S; Muzi, A; Rapinesi, C; Savoja, V; Scatena, P; Serata, D; Tatarelli, R, 2013) |
| "Treatment with eticlopride showed dose-dependent suppression of aggressive behavior in the absence of changes in mobility." | 1.36 | Dopamine activity in the lateral anterior hypothalamus modulates AAS-induced aggression through D2 but not D5 receptors. ( Melloni, RH; Schwartzer, JJ, 2010) |
| " Chronic administration of the synthetic gonadotropin (luteinising hormone) releasing hormone analogue, goserelin, reduces testosterone activity." | 1.33 | Gonadotrophin-releasing hormone agonist treatment of aggression in Alzheimer's disease: a case report. ( Raskind, MA; Rosin, RA, 2005) |
| "Spontaneous recurrent seizures were monitored with Racine's seizure severity scale." | 1.32 | Human neural stem cell transplantation reduces spontaneous recurrent seizures following pilocarpine-induced status epilepticus in adult rats. ( Chu, K; Jeon, D; Jeong, SW; Jung, KH; Kim, J; Kim, M; Kim, SU; Lee, SK; Lee, ST; Roh, JK; Shin, HS, 2004) |
| " Optimal dosing remains unclear." | 1.31 | Gabapentin for treatment of behavioral and psychological symptoms of dementia. ( Miller, LJ, 2001) |
| "Gabapentin (GBP) is a new antiepileptic drug (AED) approved for adjunctive treatment of complex partial seizures with or without seizures secondarily generalization in adults." | 1.29 | Gabapentin associated with aggressive behavior in pediatric patients with seizures. ( Lo, W; Nahata, MC; Tallian, KB; Tsao, CY, 1996) |
| " The highest dosage of 3 alpha-Diol (7." | 1.29 | Behavioral effects of 3 alpha-androstanediol. I: Modulation of sexual receptivity and promotion of GABA-stimulated chloride flux. ( Erskine, MS; Frye, CA; Van Keuren, KR, 1996) |
| "Behavioural symptoms of Alzheimer's disease, such as aggression, may determine the care patients required." | 1.28 | Serotonergic pathology is not widespread in Alzheimer patients without prominent aggressive symptoms. ( Bowen, DM; Francis, PT; Procter, AW; Stratmann, GC, 1992) |
| "Pretreatment with bicuculline (68 pmol) blocked the suppressive effects of muscimol (12 pmol) upon affective defense behavior." | 1.28 | GABA-mediated regulation of feline aggression elicited from midbrain periaqueductal gray. ( Shaikh, MB; Siegel, A, 1990) |
| "Piracetam in both doses was less effective in avoidance learning of aggressive rats." | 1.27 | Behavioral effects of piracetam in rats with isolation syndrome. ( Dimov, S; Petkov, VV; Rousseva, S, 1984) |
| "Experiments on isolated mice (CC57W males) have demonstrated that GABA antagonists (bicuculline, picrotoxin, thiosemicarbazide) increase the desocializing effects of isolation (enhance aggression and reduce intraspecies sociability), while GABA-positive drugs (muscimol, gamma-acetylenic GABA) within a certain dosage range diminish aggression and favour a temporary recovery of sociability." | 1.26 | [GABA-ergic correlates of aggression and intraspecies sociability of mice subjected to isolation]. ( Poshivalov, VP, 1981) |
| "A residual effect of DPA against seizures induced by pentetrazole was shown, i." | 1.26 | Anticonvulsant and antiaggressive properties of di-n-propyl acetate after repeated treatment. ( Ciesielski, L; Klein, M; Mandel, P; Simler, S, 1982) |
| "Muscimol was effective in the first session but did not differ significantly from saline in the second and third session." | 1.26 | Effects of sodium n-dipropylacetate, muscimol hydrobromide and (R,S) nipecotic acid amide on isolation-induced aggressive behavior in mice. ( Mandel, P; Puglisi-Allegra, S, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 52 (39.39) | 18.7374 |
| 1990's | 25 (18.94) | 18.2507 |
| 2000's | 36 (27.27) | 29.6817 |
| 2010's | 14 (10.61) | 24.3611 |
| 2020's | 5 (3.79) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, XJ | 1 |
| Wang, HJ | 1 |
| Wang, XY | 1 |
| Ning, YX | 1 |
| Gao, J | 1 |
| Sengupta, S | 1 |
| Chan, YB | 1 |
| Palavicino-Maggio, CB | 1 |
| Kravitz, EA | 1 |
| Umeda, R | 1 |
| Teranishi, H | 1 |
| Hada, K | 1 |
| Shimizu, N | 1 |
| Shiraishi, H | 1 |
| Urushibata, H | 1 |
| Lai, S | 1 |
| Shide, M | 1 |
| Carrasco Apolinario, ME | 1 |
| Higa, R | 1 |
| Shikano, K | 1 |
| Shin, T | 1 |
| Mimata, H | 1 |
| Hikida, T | 1 |
| Hanada, T | 1 |
| Hanada, R | 1 |
| Barbano, MF | 1 |
| Wang, HL | 1 |
| Zhang, S | 1 |
| Miranda-Barrientos, J | 1 |
| Estrin, DJ | 1 |
| Figueroa-González, A | 1 |
| Liu, B | 1 |
| Barker, DJ | 1 |
| Morales, M | 1 |
| Colijn, MA | 1 |
| Todd, WD | 1 |
| Fenselau, H | 1 |
| Wang, JL | 1 |
| Zhang, R | 1 |
| Machado, NL | 1 |
| Venner, A | 1 |
| Broadhurst, RY | 1 |
| Kaur, S | 1 |
| Lynagh, T | 1 |
| Olson, DP | 1 |
| Lowell, BB | 1 |
| Fuller, PM | 1 |
| Saper, CB | 1 |
| Cooney, C | 1 |
| Murphy, S | 1 |
| Tessema, H | 1 |
| Freyne, A | 1 |
| Rapinesi, C | 1 |
| Del Casale, A | 1 |
| Serata, D | 1 |
| Kotzalidis, GD | 1 |
| Scatena, P | 1 |
| Muzi, A | 1 |
| Lazanio, S | 1 |
| Savoja, V | 1 |
| Carbonetti, P | 1 |
| Fensore, C | 1 |
| Ferracuti, S | 1 |
| Angeletti, G | 1 |
| Tatarelli, R | 1 |
| Girardi, P | 1 |
| Wnuk, A | 1 |
| Kostowski, W | 1 |
| Korczyńska, J | 1 |
| Szczuka, A | 1 |
| Symonowicz, B | 1 |
| Bieńkowski, P | 1 |
| Mierzejewski, P | 1 |
| Godzińska, EJ | 1 |
| Morrison, TR | 1 |
| Ricci, LA | 2 |
| Melloni, RH | 3 |
| Hong, W | 1 |
| Kim, DW | 1 |
| Anderson, DJ | 1 |
| Rysakova, MP | 1 |
| Pavlova, IV | 1 |
| Takahashi, A | 1 |
| Lee, RX | 1 |
| Iwasato, T | 1 |
| Itohara, S | 1 |
| Arima, H | 1 |
| Bettler, B | 1 |
| Miczek, KA | 5 |
| Koide, T | 1 |
| Ende, G | 1 |
| Cackowski, S | 1 |
| Van Eijk, J | 1 |
| Sack, M | 1 |
| Demirakca, T | 1 |
| Kleindienst, N | 1 |
| Bohus, M | 1 |
| Sobanski, E | 1 |
| Krause-Utz, A | 1 |
| Schmahl, C | 1 |
| Maynard, KR | 1 |
| Hill, JL | 1 |
| Calcaterra, NE | 1 |
| Palko, ME | 1 |
| Kardian, A | 1 |
| Paredes, D | 1 |
| Sukumar, M | 1 |
| Adler, BD | 1 |
| Jimenez, DV | 1 |
| Schloesser, RJ | 1 |
| Tessarollo, L | 1 |
| Lu, B | 1 |
| Martinowich, K | 1 |
| Amiri, S | 1 |
| Haj-Mirzaian, A | 1 |
| Amini-Khoei, H | 1 |
| Razmi, A | 1 |
| Shirzadian, A | 1 |
| Rahimi-Balaei, M | 1 |
| Olson, CO | 1 |
| Mohsenzadeh, A | 1 |
| Rastegar, M | 1 |
| Zarrindast, MR | 1 |
| Ghazi-Khansari, M | 1 |
| Kim, C | 1 |
| Jeon, D | 2 |
| Kim, YH | 1 |
| Lee, CJ | 1 |
| Kim, H | 1 |
| Shin, HS | 2 |
| Sustková-Fiserová, M | 1 |
| Vávrová, J | 1 |
| Krsiak, M | 2 |
| Schwartzer, JJ | 2 |
| Tamano, H | 2 |
| Kan, F | 2 |
| Oku, N | 2 |
| Takeda, A | 2 |
| Yanowitch, R | 1 |
| Coccaro, EF | 2 |
| Dhara, AK | 1 |
| Pal, S | 1 |
| Nag Chaudhuri, AK | 1 |
| Fish, EW | 2 |
| De Bold, JF | 2 |
| De Almeida, RM | 2 |
| Cherek, DR | 1 |
| Tcheremissine, OV | 1 |
| Lane, SD | 1 |
| Pietras, CJ | 1 |
| Chu, K | 1 |
| Kim, M | 1 |
| Jung, KH | 1 |
| Lee, ST | 1 |
| Kim, J | 1 |
| Jeong, SW | 1 |
| Kim, SU | 1 |
| Lee, SK | 1 |
| Roh, JK | 1 |
| Hrabovszky, E | 1 |
| Halász, J | 2 |
| Meelis, W | 1 |
| Kruk, MR | 2 |
| Liposits, Z | 2 |
| Haller, J | 3 |
| Hoffman, DA | 1 |
| Rosin, RA | 1 |
| Raskind, MA | 1 |
| Ferrari, PF | 1 |
| Parmigiani, S | 1 |
| Hernández-Tristán, R | 1 |
| Leret, ML | 1 |
| Almeida, D | 1 |
| Saxena, K | 1 |
| Howe, M | 1 |
| Simeonova, D | 1 |
| Steiner, H | 1 |
| Chang, K | 1 |
| Lanctôt, KL | 1 |
| Herrmann, N | 1 |
| Rothenburg, L | 1 |
| Eryavec, G | 1 |
| Tóth, M | 1 |
| Kalló, I | 1 |
| Lee, G | 1 |
| Gammie, SC | 1 |
| Konovalov, S | 1 |
| Muralee, S | 1 |
| Tampi, RR | 1 |
| Demily, C | 1 |
| Franck, N | 1 |
| Hanajima, T | 1 |
| Yamada, K | 1 |
| Lee, R | 1 |
| Petty, F | 2 |
| Kenny, M | 1 |
| Leonard, BE | 2 |
| Mandel, P | 17 |
| Singhal, RL | 1 |
| Telner, JI | 1 |
| Danneberg, P | 1 |
| Weber, KH | 1 |
| Sheard, MH | 1 |
| Allikmets, LH | 1 |
| Rägo, LK | 1 |
| Valzelli, L | 1 |
| Simler, S | 12 |
| Puglisi-Allegra, S | 6 |
| Depaulis, A | 5 |
| Vergnes, M | 4 |
| Haug, M | 5 |
| Ciesielski, L | 8 |
| Moutier, R | 1 |
| Petkov, VV | 1 |
| Rousseva, S | 1 |
| Dimov, S | 1 |
| Kempf, E | 4 |
| Puglisi, S | 1 |
| Mack, G | 4 |
| Kim, L | 1 |
| Klein, M | 1 |
| Bolin, P | 1 |
| Da Vanzo, JP | 1 |
| Di Scala, G | 1 |
| Schmitt, P | 1 |
| Karli, P | 1 |
| Rodgers, RJ | 1 |
| Brain, PF | 2 |
| Kamis, A | 1 |
| Potegal, M | 2 |
| Perumal, AS | 1 |
| Barkai, AI | 1 |
| Cannova, GE | 1 |
| Blau, AD | 1 |
| Valdman, AV | 1 |
| Poshivalov, VP | 2 |
| Albert, DJ | 1 |
| Chew, GL | 1 |
| Maitre, M | 2 |
| DeFeudis, FV | 1 |
| Charras, C | 1 |
| Wolf, SM | 1 |
| Shinnar, S | 1 |
| Kang, H | 1 |
| Gil, KB | 1 |
| Moshé, SL | 1 |
| Robel, P | 1 |
| Young, J | 1 |
| Corpéchot, C | 1 |
| Mayo, W | 1 |
| Perché, F | 1 |
| Simon, H | 1 |
| Baulieu, EE | 1 |
| Coimbra, NC | 1 |
| Brandão, ML | 1 |
| Adams, DB | 1 |
| Boudreau, W | 1 |
| Cowan, CW | 1 |
| Kokonowski, C | 1 |
| Oberteuffer, K | 1 |
| Yohay, K | 1 |
| Weiger, WA | 1 |
| Ma, PM | 1 |
| Kemph, JP | 1 |
| DeVane, CL | 1 |
| Levin, GM | 1 |
| Jarecke, R | 1 |
| Miller, RL | 1 |
| Lee, DO | 1 |
| Steingard, RJ | 1 |
| Cesena, M | 1 |
| Helmers, SL | 1 |
| Riviello, JJ | 1 |
| Mikati, MA | 1 |
| Tallian, KB | 1 |
| Nahata, MC | 1 |
| Lo, W | 1 |
| Tsao, CY | 1 |
| Guillot, PV | 2 |
| Chapouthier, G | 2 |
| Frye, CA | 1 |
| Van Keuren, KR | 1 |
| Erskine, MS | 1 |
| Gladysheva, OS | 1 |
| Troitskaia, VT | 1 |
| Raevskiĭ, KS | 1 |
| Abrahám, I | 1 |
| Zelena, D | 1 |
| Juhász, G | 1 |
| Makara, GB | 1 |
| Scearce-Levie, K | 1 |
| Chen, JP | 1 |
| Gardner, E | 1 |
| Hen, R | 1 |
| Low, RA | 1 |
| Brandes, M | 1 |
| Gurvits, IG | 1 |
| Koenigsberg, HW | 1 |
| Siever, LJ | 1 |
| Stork, O | 1 |
| Ji, FY | 1 |
| Kaneko, K | 1 |
| Stork, S | 1 |
| Yoshinobu, Y | 1 |
| Moriya, T | 1 |
| Shibata, S | 1 |
| Obata, K | 1 |
| Hawkins, JW | 1 |
| Tinklenberg, JR | 1 |
| Sheikh, JI | 1 |
| Peyser, CE | 1 |
| Yesavage, JA | 1 |
| Lindenmayer, JP | 1 |
| Adamec, RE | 1 |
| Bjork, JM | 1 |
| Moeller, FG | 1 |
| Kramer, GL | 1 |
| Kram, M | 1 |
| Suris, A | 1 |
| Rush, AJ | 1 |
| Miller, LJ | 1 |
| Reynolds, SM | 1 |
| Berridge, KC | 1 |
| Pinninti, NR | 1 |
| Mahajan, DS | 1 |
| Summers, CH | 1 |
| Nicolas, LB | 1 |
| Pinoteau, W | 1 |
| Papot, S | 1 |
| Routier, S | 1 |
| Guillaumet, G | 1 |
| Mortaud, S | 1 |
| Nishimura, T | 1 |
| Schwarzer, C | 1 |
| Furtinger, S | 1 |
| Imai, H | 1 |
| Kato, N | 1 |
| Sperk, G | 1 |
| Hamani, C | 1 |
| Mello, LE | 1 |
| Hurley, SC | 1 |
| Biancosino, B | 1 |
| Facchi, A | 1 |
| Marmai, L | 1 |
| Grassi, L | 1 |
| DaVanzo, JP | 1 |
| Sydow, M | 1 |
| Earley, CJ | 1 |
| Delini-Stula, A | 2 |
| Vassout, A | 2 |
| Arnt, J | 1 |
| Scheel-Krüger, J | 1 |
| Weerts, EM | 1 |
| Miller, LG | 1 |
| Hood, KE | 1 |
| Procter, AW | 1 |
| Francis, PT | 1 |
| Stratmann, GC | 1 |
| Bowen, DM | 1 |
| Mattes, JA | 1 |
| Rouhani, S | 1 |
| Emmanouilidis, E | 1 |
| Payan, C | 1 |
| Tran, G | 1 |
| Castresana, A | 1 |
| Soulairac, A | 1 |
| Poenaru, S | 1 |
| Canonaco, M | 2 |
| Bergamo, P | 1 |
| Tavolaro, R | 1 |
| Miralto, A | 1 |
| Dutta, AS | 1 |
| Chaudhuri, AK | 1 |
| Maestripieri, D | 1 |
| Badiani, A | 1 |
| Valenti, A | 1 |
| Maggi, A | 1 |
| Yokawa, T | 1 |
| Shiota, K | 1 |
| Takahashi, M | 1 |
| Shaikh, MB | 1 |
| Siegel, A | 1 |
| Depue, RA | 1 |
| Spoont, MR | 1 |
| Manev, H | 1 |
| Pericić, D | 1 |
| Mück-Seler, D | 1 |
| Aley, KO | 1 |
| Kulkarni, SK | 1 |
| Gupta, RC | 1 |
| Bourguignon, JJ | 1 |
| Wermuth, CG | 1 |
| Molina, V | 2 |
| Gobaille, S | 2 |
| Stahmer, SD | 1 |
| Julou, L | 1 |
| Blanchard, JC | 1 |
| Dreyfus, JF | 1 |
| Muñoz-Blanco, J | 1 |
| Porras Castillo, A | 1 |
| Shekhar, A | 1 |
| DiMicco, JA | 1 |
| Clement, J | 1 |
| Cabib, S | 1 |
| Hansen, S | 1 |
| Ferreira, A | 1 |
| Spetz, JF | 1 |
| Nakao, K | 1 |
| Higashio, T | 1 |
| Inukai, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Measuring Glutamate and GABA Brain Levels in Adults With Attention Deficit Hyperactivity Disorder (ADHD) Using Magnetic Resonance Spectroscopy (MRS)[NCT04823364] | 60 participants (Anticipated) | Interventional | 2022-10-01 | Not yet recruiting | |||
| Imaging Framework for Testing GABAergic/Glutamatergic Drugs in Bipolar Alcoholics[NCT03220776] | Phase 2 | 54 participants (Actual) | Interventional | 2017-08-07 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Concentrations of GABA+, referenced to unsuppressed water and corrected for within-voxel CSF proportion, in dorsal anterior cingulate cortex measured via Proton Magnetic Resonance Spectroscopy (i.e., MEGA-PRESS). (NCT03220776)
Timeframe: Day 5 of each experimental condition
| Intervention | mmol/kg (Mean) |
|---|---|
| N-Acetylcysteine | 3.90 |
| Gabapentin | 3.93 |
| Placebo Oral Tablet | 3.73 |
Concentrations of Glx (i.e., glutamate + glutamine), referenced to unsuppressed water and corrected for within-voxel CSF proportion, in dorsal anterior cingulate cortex measured via Proton Magnetic Resonance Spectroscopy. (NCT03220776)
Timeframe: Day 5 of each experimental condition
| Intervention | mmol/kg (Mean) |
|---|---|
| N-Acetylcysteine | 21.59 |
| Gabapentin | 21.69 |
| Placebo Oral Tablet | 22.25 |
19 reviews available for gamma-aminobutyric acid and Aggression
| Article | Year |
|---|---|
The characterization of psychotic symptoms in succinic semialdehyde dehydrogenase deficiency: a review.
Topics: Adolescent; Age of Onset; Aggression; Amino Acid Metabolism, Inborn Errors; Anticonvulsants; Anxiety | 2020 |
The neurochemistry of human aggression.
Topics: Aggression; Dopamine; gamma-Aminobutyric Acid; Humans; Nervous System; Neuropeptides; Neurotransmitt | 2011 |
Social and neural determinants of aggressive behavior: pharmacotherapeutic targets at serotonin, dopamine and gamma-aminobutyric acid systems.
Topics: Adaptation, Psychological; Aggression; Animals; Brain; Dopamine; Ethanol; gamma-Aminobutyric Acid; G | 2002 |
Neurosteroids, GABAA receptors, and escalated aggressive behavior.
Topics: Aggression; Animals; gamma-Aminobutyric Acid; Humans; Neurotransmitter Agents; Progesterone; Rats; R | 2003 |
Escalated aggressive behavior: dopamine, serotonin and GABA.
Topics: Aggression; Animals; Dopamine; Drug Evaluation, Preclinical; gamma-Aminobutyric Acid; Humans; Recept | 2005 |
Anticonvulsants for the treatment of behavioral and psychological symptoms of dementia: a literature review.
Topics: Aggression; Amines; Anticonvulsants; Carbamazepine; Cognition Disorders; Cyclohexanecarboxylic Acids | 2008 |
A perspective: psychopharmacological aspects of aggression in animals and man.
Topics: Acetylcholine; Aggression; Animals; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents | 1983 |
Chemical structure and biological activity of the diazepines.
Topics: Acetylcholine; Aggression; Animals; Anti-Anxiety Agents; Anxiety; Autonomic Nervous System; Behavior | 1983 |
Clinical pharmacology of aggressive behavior.
Topics: Adolescent; Adult; Aged; Aggression; Anger; Anti-Anxiety Agents; Benzodiazepines; Brain Chemistry; C | 1984 |
Reflections on experimental and human pathology of aggression.
Topics: Aggression; Animals; Brain; Diet; Disease Models, Animal; Dopamine; Emotions; gamma-Aminobutyric Aci | 1984 |
The septal forebrain and the inhibitory modulation of attack and defense in the rat. A review.
Topics: Adrenergic Fibers; Age Factors; Aggression; Agonistic Behavior; Anger; Animals; Brain Mapping; Castr | 1980 |
Inhibitory amino acids, aggressiveness, and convulsions.
Topics: Aggression; Amino Acids; Animals; Anticonvulsants; gamma-Aminobutyric Acid; Humans; Seizures; Taurin | 1981 |
A theory of schizophrenia: role of environment.
Topics: Aggression; Animals; Brain Chemistry; Disease Models, Animal; Environment; gamma-Aminobutyric Acid; | 1982 |
Biosynthesis and assay of neurosteroids in rats and mice: functional correlates.
Topics: Adrenalectomy; Aggression; Aging; Animals; Behavior, Animal; Dehydroepiandrosterone; Dihydrotestoste | 1995 |
Neurotransmitter dysfunction in patients with borderline personality disorder.
Topics: Acetylcholine; Affect; Aggression; Animals; Arginine Vasopressin; Borderline Personality Disorder; B | 2000 |
The pathophysiology of agitation.
Topics: Aggression; Behavioral Symptoms; Bipolar Disorder; Dementia; Dopamine; gamma-Aminobutyric Acid; Huma | 2000 |
Mechanisms for quick and variable responses.
Topics: Aggression; Animals; Arginine Vasopressin; Brain Chemistry; Catecholamines; Corticosterone; Corticot | 2001 |
Lamotrigine update and its use in mood disorders.
Topics: Acetates; Aggression; Amines; Antidepressive Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; | 2002 |
Pharmacodynamics of benzodiazepines.
Topics: Aggression; Animals; Anti-Anxiety Agents; Anxiety; Astrocytes; Autonomic Nervous System; Behavior; B | 1985 |
2 trials available for gamma-aminobutyric acid and Aggression
| Article | Year |
|---|---|
Divalproex sodium reduces overall aggression in youth at high risk for bipolar disorder.
Topics: Adolescent; Affect; Aggression; Antimanic Agents; Attention Deficit and Disruptive Behavior Disorder | 2006 |
Gabapentin toxicity in children manifesting as behavioral changes.
Topics: Acetates; Affect; Aggression; Amines; Anticonvulsants; Behavior; Child; Cyclohexanecarboxylic Acids; | 1995 |
111 other studies available for gamma-aminobutyric acid and Aggression
| Article | Year |
|---|---|
GABABR1 in DRN mediated GABA to regulate 5-HT expression in multiple brain regions in male rats with high and low aggressive behavior.
Topics: Aggression; Animals; Brain; Dorsal Raphe Nucleus; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; | 2021 |
GABA transmission from mAL interneurons regulates aggression in
Topics: Aggression; Animals; Behavior, Animal; Brain; Courtship; Drosophila melanogaster; Drosophila Protein | 2022 |
Vrk2 deficiency elicits aggressive behavior in female zebrafish.
Topics: Aggression; Animals; Female; gamma-Aminobutyric Acid; Genome-Wide Association Study; Protein Serine- | 2022 |
VTA Glutamatergic Neurons Mediate Innate Defensive Behaviors.
Topics: Aggression; Animals; Escape Reaction; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Hypothalamic A | 2020 |
A hypothalamic circuit for the circadian control of aggression.
Topics: Aggression; Animals; Brain Mapping; Circadian Rhythm; Corticosterone; Excitatory Postsynaptic Potent | 2018 |
Use of low-dose gabapentin for aggressive behavior in vascular and Mixed Vascular/Alzheimer Dementia.
Topics: Aged; Aged, 80 and over; Aggression; Alzheimer Disease; Amines; Cyclohexanecarboxylic Acids; Dementi | 2013 |
Epilepsy and brain injury: a case report of a dramatic neuropsychiatric vicious circle.
Topics: Accidents, Traffic; Aggression; Amines; Anterior Temporal Lobectomy; Anticonvulsants; Brain Injuries | 2013 |
Brain GABA and glutamate levels in workers of two ant species (Hymenoptera: Formicidae): interspecific differences and effects of queen presence/absence.
Topics: Aggression; Animals; Ants; Brain; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Glu | 2014 |
γ-Aminobutyric acid neural signaling in the lateroanterior hypothalamus modulates aggressive behavior in adolescent anabolic/androgenic steroid-treated hamsters.
Topics: Aggression; Anabolic Agents; Androgens; Animals; Behavior, Animal; Bicuculline; Cricetinae; Dose-Res | 2014 |
Antagonistic control of social versus repetitive self-grooming behaviors by separable amygdala neuronal subsets.
Topics: Aggression; Amygdala; Animals; Female; gamma-Aminobutyric Acid; Grooming; In Vitro Techniques; Male; | 2014 |
[Behavior of high- and low-anxiety rats after modulation of GABAergic transmission in basolateral amygdala].
Topics: Aggression; Animals; Anxiety; Basolateral Nuclear Complex; Bicuculline; Functional Laterality; GABA | 2014 |
Glutamate input in the dorsal raphe nucleus as a determinant of escalated aggression in male mice.
Topics: Aggression; Animals; Baclofen; Dorsal Raphe Nucleus; Dose-Response Relationship, Drug; gamma-Aminobu | 2015 |
Impulsivity and Aggression in Female BPD and ADHD Patients: Association with ACC Glutamate and GABA Concentrations.
Topics: Adult; Aggression; Attention Deficit Disorder with Hyperactivity; Borderline Personality Disorder; C | 2016 |
Impulsivity and Aggression in Female BPD and ADHD Patients: Association with ACC Glutamate and GABA Concentrations.
Topics: Adult; Aggression; Attention Deficit Disorder with Hyperactivity; Borderline Personality Disorder; C | 2016 |
Impulsivity and Aggression in Female BPD and ADHD Patients: Association with ACC Glutamate and GABA Concentrations.
Topics: Adult; Aggression; Attention Deficit Disorder with Hyperactivity; Borderline Personality Disorder; C | 2016 |
Impulsivity and Aggression in Female BPD and ADHD Patients: Association with ACC Glutamate and GABA Concentrations.
Topics: Adult; Aggression; Attention Deficit Disorder with Hyperactivity; Borderline Personality Disorder; C | 2016 |
Functional Role of BDNF Production from Unique Promoters in Aggression and Serotonin Signaling.
Topics: Aggression; Animals; Brain; Brain-Derived Neurotrophic Factor; gamma-Aminobutyric Acid; Gene Express | 2016 |
Protective effects of gabapentin against the seizure susceptibility and comorbid behavioral abnormalities in the early socially isolated mice.
Topics: Aggression; Amines; Animals; Anticonvulsants; Anxiety; Behavior, Animal; Comorbidity; Cyclohexanecar | 2017 |
Deletion of N-type Ca(2+) channel Ca(v)2.2 results in hyperaggressive behaviors in mice.
Topics: Aggression; Animals; Calcium Channels, N-Type; Chromatography, High Pressure Liquid; gamma-Aminobuty | 2009 |
Brain levels of GABA, glutamate and aspartate in sociable, aggressive and timid mice: an in vivo microdialysis study.
Topics: Aggression; Animals; Aspartic Acid; Behavior, Animal; Brain; Excitatory Amino Acids; gamma-Aminobuty | 2009 |
Interactions between the dopaminergic and GABAergic neural systems in the lateral anterior hypothalamus of aggressive AAS-treated hamsters.
Topics: Aggression; Anabolic Agents; Androgens; Animals; Cricetinae; Dopamine; Fluorescent Antibody Techniqu | 2009 |
Ameliorative effect of Yokukansan on social isolation-induced aggressive behavior of zinc-deficient young mice.
Topics: Aggression; Animals; Behavior, Animal; Brain; Chromatography, High Pressure Liquid; Corticosterone; | 2010 |
Dopamine activity in the lateral anterior hypothalamus modulates AAS-induced aggression through D2 but not D5 receptors.
Topics: Aggression; Androgens; Animals; Benzazepines; Cricetinae; Dopamine Antagonists; Dopamine D2 Receptor | 2010 |
Psychopharmacological studies on Tragia involucrata root extract.
Topics: Aggression; Animals; Anticonvulsants; Avoidance Learning; Behavior, Animal; Body Temperature; Brain | 2002 |
Acute effects of gabapentin on laboratory measures of aggressive and escape responses of adult parolees with and without a history of conduct disorder.
Topics: Acetates; Adult; Aggression; Amines; Conduct Disorder; Cyclohexanecarboxylic Acids; Escape Reaction; | 2004 |
Human neural stem cell transplantation reduces spontaneous recurrent seizures following pilocarpine-induced status epilepticus in adult rats.
Topics: Aggression; Animals; Animals, Newborn; Behavior, Animal; Cell Count; Cell Death; Cells, Cultured; El | 2004 |
Neurochemical characterization of hypothalamic neurons involved in attack behavior: glutamatergic dominance and co-expression of thyrotropin-releasing hormone in a subset of glutamatergic neurons.
Topics: Aggression; Animals; gamma-Aminobutyric Acid; Gene Expression; Glutamic Acid; Imaging, Three-Dimensi | 2005 |
Tiagabine for rage, aggression, and anxiety.
Topics: Adolescent; Adult; Aggression; Anxiety; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; | 2005 |
Gonadotrophin-releasing hormone agonist treatment of aggression in Alzheimer's disease: a case report.
Topics: Aged; Aggression; Alzheimer Disease; Amines; Antipsychotic Agents; Benzodiazepines; Cyclohexanecarbo | 2005 |
Effect of intrauterine position on sex differences in the gabaergic system and behavior of rats.
Topics: Aggression; Animals; Behavior, Animal; Embryo, Mammalian; Estradiol; Exploratory Behavior; Female; g | 2006 |
Behavioral correlates of GABAergic disruption in Alzheimer's disease.
Topics: Affect; Aged; Aged, 80 and over; Aggression; Alzheimer Disease; Cognition Disorders; Depressive Diso | 2007 |
The activation of prefrontal cortical neurons in aggression--a double labeling study.
Topics: Adrenalectomy; Aggression; Analysis of Variance; Animals; Behavior, Animal; Cell Count; Corticostero | 2006 |
GABA enhancement of maternal defense in mice: possible neural correlates.
Topics: Aggression; Animals; Body Weight; Chlordiazepoxide; Female; GABA Modulators; gamma-Aminobutyric Acid | 2007 |
Gabapentin for ultra resistant schizophrenia with aggressive behavior.
Topics: Adult; Aggression; Amines; Anticonvulsants; Antipsychotic Agents; Cyclohexanecarboxylic Acids; Drug | 2008 |
Enhancement of social isolation-induced aggressive behavior of young mice by zinc deficiency.
Topics: Aggression; Animals; Behavior, Animal; Body Weight; Chromatography, High Pressure Liquid; Corticoste | 2008 |
Cerebrospinal fluid GABA concentration: relationship with impulsivity and history of suicidal behavior, but not aggression, in human subjects.
Topics: Adult; Aggression; Female; gamma-Aminobutyric Acid; Humans; Impulsive Behavior; Male; Personality Di | 2009 |
The effects of strain differences and emotional status of rats on the behavioural and neurochemical effects of chronic treatment with apomorphine.
Topics: Aggression; Animals; Apomorphine; Behavior, Animal; Brain; Dopamine; Emotions; gamma-Aminobutyric Ac | 1980 |
[The role of inhibitory neurotransmission in aggressive behavior].
Topics: Aggression; Animals; Apomorphine; Brain Chemistry; Choline; Dopamine; Female; gamma-Aminobutyric Aci | 1982 |
The action of benzodiazepine antagonist Ro 15-1788 on the effects of GABA-ergic drugs.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aggression; Animals; Baclofen; Benzodiazepines; Benzodiazepinones; B | 1983 |
Effects of n-di-propylacetate on aggressive behavior and brain GABA level in isolated mice.
Topics: Aggression; Animals; Brain; gamma-Aminobutyric Acid; Humans; Kinetics; Male; Mice; Mice, Inbred DBA; | 1983 |
Gabaergic modulation of mouse-killing in the rat.
Topics: Aggression; Aminocaproates; Animals; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Isoxazoles; | 1984 |
Influence of castration and brain GABA levels in three strains of mice on aggression towards lactating intruders.
Topics: Aggression; Animals; Brain; Castration; Female; gamma-Aminobutyric Acid; Humans; Lactation; Male; Mi | 1984 |
Behavioral effects of piracetam in rats with isolation syndrome.
Topics: Aggression; Animals; Avoidance Learning; Brain Chemistry; gamma-Aminobutyric Acid; Humans; Male; Pir | 1984 |
Induction of mouse-killing in the rat by intraventricular injection of a GABA-agonist.
Topics: Aggression; Animals; Arousal; Bicuculline; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid | 1983 |
Comparison of the effects of GABA-mimetic agents on two types of aggressive behavior.
Topics: Aggression; Animals; gamma-Aminobutyric Acid; Humans; Injections; Injections, Intraperitoneal; Mice; | 1983 |
Studies on the involvement of GABA in the aggression directed by groups of intact or gonadectomized male and female mice towards lactating intruders.
Topics: Aggression; Animals; Brain Chemistry; Castration; Dose-Response Relationship, Drug; Female; gamma-Am | 1980 |
Effects of sodium n-dipropylacetate, muscimol hydrobromide and (R,S) nipecotic acid amide on isolation-induced aggressive behavior in mice.
Topics: Aggression; Animals; gamma-Aminobutyric Acid; Humans; Male; Mice; Motor Activity; Muscimol; Nipecoti | 1980 |
Involvement of the GABAergic system on shock-induced aggressive behavior in two strains of mice.
Topics: 4-Aminobutyrate Transaminase; Aggression; Allylglycine; Animals; Brain Chemistry; Dose-Response Rela | 1981 |
Anticonvulsant and antiaggressive properties of di-n-propyl acetate after repeated treatment.
Topics: Acoustic Stimulation; Aggression; Animals; Anticonvulsants; Brain; Female; gamma-Aminobutyric Acid; | 1982 |
The influence of isolation and aminooxyacetic acid (AOAA) on GABA in muricidal rats.
Topics: Acetates; Aggression; Aminooxyacetic Acid; Amygdala; Animals; Brain; gamma-Aminobutyric Acid; Humans | 1982 |
[Implication of gamma-aminobutyric acid (GABA) at the mesencephalic central gray level, in the elaboration of flight responses].
Topics: Aggression; Animals; Bicuculline; Escape Reaction; gamma-Aminobutyric Acid; Humans; Male; Mesencepha | 1982 |
GABAergic influences on defensive fighting in rats.
Topics: Aggression; Aminocaproates; Animals; Baclofen; Bicuculline; Electroshock; gamma-Aminobutyric Acid; H | 1982 |
Studies on diverse models of aggression in drug research.
Topics: Aggression; Animals; Castration; Conflict, Psychological; Electroshock; Female; gamma-Aminobutyric A | 1982 |
GABA binding in the brains of aggressive and non-aggressive female hamsters.
Topics: Aggression; Animals; Binding Sites; Brain; Cricetinae; Diencephalon; Dihydroalprenolol; Female; gamm | 1982 |
Neuropharmacology of intraspecific aggression and sociability in isolated mice.
Topics: Aggression; Animals; Dopamine; gamma-Aminobutyric Acid; Humans; Male; Mice; Norepinephrine; Serotoni | 1982 |
[GABA-ergic correlates of aggression and intraspecies sociability of mice subjected to isolation].
Topics: Aggression; Alkynes; Aminocaproates; Animals; Bicuculline; gamma-Aminobutyric Acid; Humans; Male; Mi | 1981 |
gamma-Aminobutyric acid in brain areas of isolated aggressive or non-aggressive inbred strains of mice.
Topics: Aggression; Animals; Brain Chemistry; gamma-Aminobutyric Acid; Humans; Male; Mice; Mice, Inbred C57B | 1982 |
GABAergic nigro-collicular pathways modulate the defensive behaviour elicited by midbrain tectum stimulation.
Topics: Aggression; Animals; Bicuculline; Electric Stimulation; Escape Reaction; GABA Antagonists; gamma-Ami | 1993 |
Offense produced by chemical stimulation of the anterior hypothalamus of the rat.
Topics: Aggression; Agonistic Behavior; Animals; Brain Mapping; Female; GABA Antagonists; gamma-Aminobutyric | 1993 |
Serotonin-containing neurons in lobsters: origins and characterization of inhibitory postsynaptic potentials.
Topics: Aggression; Animals; Behavior, Animal; Clone Cells; gamma-Aminobutyric Acid; Ganglia; Membrane Poten | 1993 |
Treatment of aggressive children with clonidine: results of an open pilot study.
Topics: Adolescent; Aggression; Brain; Child; Child Behavior Disorders; Child, Preschool; Clonidine; Female; | 1993 |
Behavioral side effects of gabapentin in children.
Topics: Acetates; Aggression; Akathisia, Drug-Induced; Amines; Anticonvulsants; Attention Deficit Disorder w | 1996 |
Gabapentin associated with aggressive behavior in pediatric patients with seizures.
Topics: Acetates; Adolescent; Age Factors; Aggression; Amines; Anticonvulsants; Child; Child Behavior Disord | 1996 |
Intermale aggression and dark/light preference in ten inbred mouse strains.
Topics: Aggression; Agonistic Behavior; Animals; Arousal; Choice Behavior; Darkness; gamma-Aminobutyric Acid | 1996 |
Behavioral effects of 3 alpha-androstanediol. I: Modulation of sexual receptivity and promotion of GABA-stimulated chloride flux.
Topics: Aggression; Androstane-3,17-diol; Animals; Brain Chemistry; Chloride Channels; Estradiol; Estrus; Fe | 1996 |
Intermale aggression, GAD activity in the olfactory bulbs and Y chromosome effect in seven inbred mouse strains.
Topics: Aggression; Animals; gamma-Aminobutyric Acid; Glutamate Dehydrogenase; Kinetics; Male; Mice; Mice, I | 1998 |
[Effect of intranasal administration of gamma-aminobutyric acid on intraspecies aggression in male mice].
Topics: Administration, Intranasal; Aggression; Animals; Blood-Brain Barrier; gamma-Aminobutyric Acid; Injec | 1998 |
Aggressive experience affects the sensitivity of neurons towards pharmacological treatment in the hypothalamic attack area.
Topics: Aggression; Animals; Bicuculline; Excitatory Amino Acid Agonists; GABA Antagonists; GABA-A Receptor | 1998 |
5-HT receptor knockout mice: pharmacological tools or models of psychiatric disorders.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aggression; Animals; Behavior, Animal; Cocaine; Disease Models, Anim | 1999 |
Gabapentin for the management of agitation.
Topics: Acetates; Aggression; Amines; Cyclohexanecarboxylic Acids; GABA Agonists; Gabapentin; gamma-Aminobut | 1999 |
Postnatal development of a GABA deficit and disturbance of neural functions in mice lacking GAD65.
Topics: Age Factors; Aggression; Animals; Anxiety; Aspartic Acid; Brain; Brain Chemistry; Circadian Rhythm; | 2000 |
A retrospective chart review of gabapentin for the treatment of aggressive and agitated behavior in patients with dementias.
Topics: Acetates; Aged; Aged, 80 and over; Aggression; Amines; Antimanic Agents; California; Cyclohexanecarb | 2000 |
Evidence that long-lasting potentiation of amygdala efferents in the right hemisphere underlies pharmacological stressor (FG-7142) induced lasting increases in anxiety-like behaviour: role of GABA tone in initiation of brain and behavioural changes.
Topics: Aggression; Amygdala; Animals; Anticonvulsants; Anxiety; Behavior, Animal; Brain Chemistry; Carbolin | 2000 |
Plasma GABA levels correlate with aggressiveness in relatives of patients with unipolar depressive disorder.
Topics: Adult; Age Factors; Aggression; Biomarkers; Case-Control Studies; Depressive Disorder; Family; Femal | 2001 |
Gabapentin for treatment of behavioral and psychological symptoms of dementia.
Topics: Acetates; Aggression; Amines; Behavior; Cyclohexanecarboxylic Acids; Dementia, Vascular; Excitatory | 2001 |
Fear and feeding in the nucleus accumbens shell: rostrocaudal segregation of GABA-elicited defensive behavior versus eating behavior.
Topics: Aggression; Analysis of Variance; Animals; Appetitive Behavior; Behavior, Animal; Dose-Response Rela | 2001 |
Gabapentin-associated aggression.
Topics: Acetates; Adult; Aggression; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids | 2001 |
Aggressive behavior induced by the steroid sulfatase inhibitor COUMATE and by DHEAS in CBA/H mice.
Topics: Aggression; Animals; Arylsulfatases; Behavior, Animal; Brain; Coumarins; Dehydroepiandrosterone Sulf | 2001 |
Changes in the GABA-ergic system induced by trimethyltin application in the rat.
Topics: Aggression; Animals; Cell Death; Enzyme Induction; gamma-Aminobutyric Acid; Gene Expression Regulati | 2001 |
Spontaneous recurrent seizures and neuropathology in the chronic phase of the pilocarpine and picrotoxin model epilepsy.
Topics: Acetylcholine; Action Potentials; Aggression; Animals; Behavior, Animal; Brain; Chronic Disease; Dis | 2002 |
Gabapentin treatment of impulsive-aggressive behaviour.
Topics: Acetates; Adult; Aggression; Amines; Antimanic Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids | 2002 |
Inhibition of isolation-induced aggressive behavior with GABA transaminase inhibitors.
Topics: 4-Aminobutyrate Transaminase; Aggression; Aminooxyacetic Acid; Animals; Brain Chemistry; Depression, | 1979 |
Involvement of central GABA-ergic systems in convulsions and aggressive behavior.
Topics: 4-Aminobutyrate Transaminase; Aggression; Allylglycine; Animals; Bicuculline; Brain; Fatty Acids; ga | 1979 |
The effect of testosterone and cyproterone acetate on the concentration of gamma-aminobutyric acid in brain areas of aggressive and non-aggressive mice.
Topics: Aggression; Aminobutyrates; Animals; Brain Chemistry; Cyproterone; gamma-Aminobutyric Acid; Humans; | 1977 |
Modulatory effects of baclofen muscimol and GABA on interspecific aggressive behaviour in the rat.
Topics: Aggression; Aminobutyrates; Animals; Baclofen; gamma-Aminobutyric Acid; Humans; Male; Muscimol; Olfa | 1978 |
GABA in the ventral tegmental area: differential regional effects on locomotion, aggression and food intake after microinjection of GABA agonists and antagonists.
Topics: Aggression; Animals; Apomorphine; Behavior, Animal; Bicuculline; Carbachol; Cerebral Cortex; Dopamin | 1979 |
Influence of baclofen and GABA-minetic agents on spontaneous and olfactory-bulb-ablation-induced muricidal behaviour in the rat.
Topics: Aggression; Aminobutyrates; Animals; Baclofen; gamma-Aminobutyric Acid; Humans; Male; Motor Activity | 1978 |
[Inhibition of mouse-killing behavior by rats with taurine, GABA, and its analogues].
Topics: Aggression; Aminobutyrates; Animals; gamma-Aminobutyric Acid; Humans; Olfactory Bulb; Rats; Taurine | 1976 |
Increased GABAA-dependent chloride uptake in mice selectively bred for low aggressive behavior.
Topics: Aggression; Animals; Chlorides; Flumazenil; gamma-Aminobutyric Acid; Genetics, Behavioral; Male; Mic | 1992 |
Serotonergic pathology is not widespread in Alzheimer patients without prominent aggressive symptoms.
Topics: Aged; Aged, 80 and over; Aggression; Alzheimer Disease; Biomarkers; Cerebral Cortex; Choline O-Acety | 1992 |
Valproic acid for nonaffective aggression in the mentally retarded.
Topics: Adult; Affect; Aggression; Animals; Female; gamma-Aminobutyric Acid; Humans; Intellectual Disability | 1992 |
Effects of alcohol dependence on shock-induced fighting: action of muscimol and homotaurine.
Topics: Aggression; Alcoholism; Animals; Body Weight; Electroshock; Ethanol; gamma-Aminobutyric Acid; Male; | 1992 |
Role of the GABA chloride ion channel component on aggressive behavior in the male crab.
Topics: Aggression; Agonistic Behavior; Animals; Arousal; Brachyura; Brain; Chloride Channels; gamma-Aminobu | 1991 |
Neuropharmacological studies on the venom of Vipera russelli.
Topics: Aggression; Animals; Behavior, Animal; Body Temperature; Brain; Chlorpromazine; Dose-Response Relati | 1991 |
Prepartal chronic stress increases anxiety and decreases aggression in lactating female mice.
Topics: Aggression; Agonistic Behavior; Animals; Arousal; Brain; Brain Mapping; Female; gamma-Aminobutyric A | 1991 |
Effects of progesterone on [35S] t-butylbicyclophosphorothionate binding in some forebrain areas of the female rat and its correlation to aggressive behavior.
Topics: Aggression; Amygdala; Animals; Autoradiography; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Co | 1990 |
Hyper-running activity originating from the hypothalamus is blocked by GABA.
Topics: Aggression; Animals; Brain Mapping; Escape Reaction; Female; gamma-Aminobutyric Acid; Motor Activity | 1990 |
GABA-mediated regulation of feline aggression elicited from midbrain periaqueductal gray.
Topics: Aggression; Animals; Bicuculline; Cats; Dose-Response Relationship, Drug; Electric Stimulation; Fema | 1990 |
Conceptualizing a serotonin trait. A behavioral dimension of constraint.
Topics: Aggression; Animals; Arousal; Brain; Dopamine; gamma-Aminobutyric Acid; Humans; Hydroxyindoleacetic | 1986 |
Inhibitory influence of dihydroergosine on the aggressiveness of rats and mice.
Topics: Aggression; Animals; Ergotamines; gamma-Aminobutyric Acid; Hydroxyindoleacetic Acid; Hypothalamus; M | 1989 |
GABAergic agents and clonidine attenuate footshock-induced aggression in mice.
Topics: Aggression; Animals; Baclofen; Clonidine; Diazepam; Electroshock; gamma-Aminobutyric Acid; Male; Mic | 1989 |
Effects of muscimol, cetyl-GABA, pentetrazol and picrotoxin on timidity during intraspecies conflict in mice.
Topics: Aggression; Animals; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Pentylenetetra | 1989 |
Effects of taurine and taurine analogues on aggressive behavior.
Topics: Aggression; Animals; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Neurotransmitter Agents; | 1985 |
Pharmacological and clinical studies of cyclopyrrolones: zopiclone and suriclone.
Topics: Aggression; Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety Disorders; Azabicyclo Compounds; | 1985 |
Changes in neurotransmitter amino acids content in several CNS areas from aggressive and non-aggressive bull strains.
Topics: Aggression; Amino Acids; Animals; Aspartic Acid; Brain Stem; Cattle; Cerebellum; Female; gamma-Amino | 1987 |
Elicitation of conspecific attack or defense in the male rat by intraventricular injection of a GABA agonist or antagonist.
Topics: Aggression; Animals; Bicuculline; Brain; gamma-Aminobutyric Acid; Injections, Intraventricular; Isox | 1985 |
Effects of the potentiation of the GABAergic neurotransmission in the olfactory bulbs on mouse-killing behavior.
Topics: Aggression; Aminocaproates; Animals; Brain Chemistry; Drug Synergism; gamma-Aminobutyric Acid; Isoni | 1986 |
Differential effects of ethyl (R,S)-nipecotate on the behaviors of highly and minimally aggressive female golden hamsters.
Topics: Aggression; Animals; Behavior, Animal; Brain; Cricetinae; Feeding Behavior; Female; gamma-Aminobutyr | 1986 |
Defense reaction elicited by injection of GABA antagonists and synthesis inhibitors into the posterior hypothalamus in rats.
Topics: Aggression; Animals; Bicuculline; Brain Mapping; gamma-Aminobutyric Acid; Hypothalamus; Hypothalamus | 1987 |
Age-dependent changes of brain GABA levels, turnover rates and shock-induced aggressive behavior in inbred strains of mice.
Topics: Age Factors; Aggression; Animals; Brain; Electroshock; gamma-Aminobutyric Acid; Male; Mice; Mice, In | 1987 |
Elicitation of intraspecific defensive behaviors in the rat by microinjection of picrotoxin, a gamma-aminobutyric acid antagonist, into the midbrain periaqueductal gray matter.
Topics: Aggression; Animals; Brain Mapping; gamma-Aminobutyric Acid; Male; Microinjections; Periaqueductal G | 1986 |
Effects of bicuculline infusions in the ventromedial hypothalamus and amygdaloid complex on food intake and affective behavior in mother rats.
Topics: Aggression; Amygdala; Animals; Bicuculline; Brain Mapping; Fear; Feeding Behavior; Female; gamma-Ami | 1986 |
Effects of naloxone administration on attack by castrated male mice on lactating intruders.
Topics: Aggression; Animals; Endorphins; Female; gamma-Aminobutyric Acid; Gonadal Steroid Hormones; Lactatio | 1986 |
Antagonism of picrotoxin against the taming effect of carbamazepine on footshock induced fighting behavior in mice.
Topics: Aggression; Animals; Bicuculline; Carbamazepine; Diazepam; Electroshock; gamma-Aminobutyric Acid; Ha | 1985 |