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gamma-aminobutyric acid and Adenocarcinoma

gamma-aminobutyric acid has been researched along with Adenocarcinoma in 18 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Adenocarcinoma: A malignant epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
"We report a case of neutropenia occurring in a patient receiving gabapentin for neuropathic pain."7.72Neutropenia occurring after starting gabapentin for neuropathic pain. ( Derbyshire, E; Martin, D, 2004)
"A 54-year-old woman was undergoing chemotherapy with gemcitabine and oxaliplatin (GEMOX) for stage II-B pancreatic adenocarcinoma."3.74Successful amelioration of oxaliplatin-induced hyperexcitability syndrome with the antiepileptic pregabalin in a patient with pancreatic cancer. ( Hashmi, S; Saif, MW, 2008)
"We report a case of neutropenia occurring in a patient receiving gabapentin for neuropathic pain."3.72Neutropenia occurring after starting gabapentin for neuropathic pain. ( Derbyshire, E; Martin, D, 2004)
" Male Wistar rats fed with 2% gabapentin (1-(aminomethyl)cyclohexane acetic acid) in diet for 2 years developed pancreatic exocrine adenomas and adenocarcinomas."3.69Absence of Ki-ras mutations in exocrine pancreatic tumors from male rats chronically exposed to gabapentin. ( de la Iglesia, FA; Fowler, ML; Lalwani, ND; Reddy, JK; Sigler, RE, 1995)
" Of 11 transplantable and 7,12-dimethylbenz[a]anthracene-induced adenocarcinomas of the rat, all nonmetastasizing tumors could be distinguished from metastasizing tumors by the accumulation of high glutamine pools and significant-to-high cystathionine pools."3.66Free amino acid pools of rodent mammary tumors. ( Ip, C; Kim, U; Pine, MJ, 1982)
"Lung cancer is the leading cause of cancer death in men and women worldwide, with over a million deaths annually."2.47Lung carcinoma signaling pathways activated by smoking. ( Fu, JH; Guo, M; Wen, J; Zhang, W, 2011)
" In addition to reassurance, pregabalin was prescribed for these myotonic symptoms at a dosage of 50 mg by mouth three times daily."1.35Successful amelioration of oxaliplatin-induced hyperexcitability syndrome with the antiepileptic pregabalin in a patient with pancreatic cancer. ( Hashmi, S; Saif, MW, 2008)
"Gabapentin, which has been suggested as an adjuvant analgesic for neuropathic pain introduced orally, rapidly and significantly alleviated his pain and we could subsequently dispense with ketamine and mexiletine."1.34[Gabapentin mitigates neuropathic pain in cancer patients--a case report]. ( Okada, M; Shinjo, T, 2007)
"His neuropathic pain was not sufficiently responsive to the combination therapy of opioids, non-steroidal antiinflammatory drugs (NSAIDs), continuous infusion of subcutaneous ketamine and oral mexiletine."1.34[Gabapentin mitigates neuropathic pain in cancer patients--a case report]. ( Okada, M; Shinjo, T, 2007)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19902 (11.11)18.7374
1990's3 (16.67)18.2507
2000's7 (38.89)29.6817
2010's6 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Solorzano, SR1
Imaz-Rosshandler, I1
Camacho-Arroyo, I1
García-Tobilla, P1
Morales-Montor, G1
Salazar, P1
Arena-Ortiz, ML1
Rodríguez-Dorantes, M1
Jiang, SH1
Zhu, LL1
Zhang, M1
Li, RK1
Yang, Q1
Yan, JY1
Zhang, C1
Yang, JY1
Dong, FY1
Dai, M1
Hu, LP1
Li, J1
Li, Q1
Wang, YH1
Yang, XM1
Zhang, YL1
Nie, HZ1
Zhu, L1
Zhang, XL1
Tian, GA1
Zhang, XX1
Cao, XY1
Tao, LY1
Huang, S1
Jiang, YS1
Hua, R1
Qian Luo, K1
Gu, JR1
Sun, YW1
Hou, S1
Zhang, ZG1
Ippolito, JE1
Piwnica-Worms, D1
Fleming, GF1
Al-Wadei, HA2
Schuller, HM2
Wen, J1
Fu, JH1
Zhang, W1
Guo, M1
Matsutani, N1
Kawamura, M1
Correa García, S1
Casas, A1
Perotti, C1
Batlle, A1
Bermúdez Moretti, M1
Maemura, K1
Yamauchi, H1
Hayasaki, H1
Kanbara, K1
Tamayama, T1
Hirata, I1
Watanabe, M1
Derbyshire, E1
Martin, D1
Okada, M1
Shinjo, T1
Saif, MW1
Hashmi, S1
Majidi, M1
Pine, MJ1
Kim, U1
Ip, C1
Fowler, ML1
Sigler, RE1
de la Iglesia, FA1
Reddy, JK1
Lalwani, ND1
Kleinrok, Z2
Matuszek, M1
Jesipowicz, J1
Matuszek, B1
Opolski, A2
Radzikowski, C2
Mazurkiewicz, M1
Wietrzyk, J1
Dereux-Mortier, SA1
Dereux, JF1
Gallois, P1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
An Open Label, Non-Randomized Multisite Phase II Trial Combining Bevacizumab, Atezolizumab and Rucaparib for the Treatment of Previously Treated Recurrent and Progressive Endometrial Carcinoma[NCT03694262]Phase 230 participants (Actual)Interventional2019-07-19Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for gamma-aminobutyric acid and Adenocarcinoma

ArticleYear
Second-Line Therapy for Endometrial Cancer: The Need for Better Options.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Nov-01, Volume: 33, Issue:31

    Topics: Adenocarcinoma; Amines; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Clinical Trials

2015
Lung carcinoma signaling pathways activated by smoking.
    Chinese journal of cancer, 2011, Volume: 30, Issue:8

    Topics: Adenocarcinoma; Carcinoma, Squamous Cell; ErbB Receptors; gamma-Aminobutyric Acid; Humans; Lung Neop

2011

Other Studies

16 other studies available for gamma-aminobutyric acid and Adenocarcinoma

ArticleYear
GABA promotes gastrin-releasing peptide secretion in NE/NE-like cells: Contribution to prostate cancer progression.
    Scientific reports, 2018, 07-06, Volume: 8, Issue:1

    Topics: Adenocarcinoma; Aged; Cohort Studies; Disease Progression; GABA Agents; gamma-Aminobutyric Acid; Gas

2018
GABRP regulates chemokine signalling, macrophage recruitment and tumour progression in pancreatic cancer through tuning KCNN4-mediated Ca
    Gut, 2019, Volume: 68, Issue:11

    Topics: Adenocarcinoma; Animals; Chemokines; Disease Models, Animal; gamma-Aminobutyric Acid; Humans; Interm

2019
A fluorescence-coupled assay for gamma aminobutyric acid (GABA) reveals metabolic stress-induced modulation of GABA content in neuroendocrine cancer.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Adenocarcinoma; Atlases as Topic; Carcinoma, Neuroendocrine; Cell Line, Tumor; Enzyme Assays; Fluore

2014
Nicotinic receptor-associated modulation of stimulatory and inhibitory neurotransmitters in NNK-induced adenocarcinoma of the lungs and pancreas.
    The Journal of pathology, 2009, Volume: 218, Issue:4

    Topics: Adenocarcinoma; Animals; Blotting, Western; Carcinoma, Pancreatic Ductal; Cricetinae; Cyclic AMP; El

2009
Significant improvement of chronic pain by Pregabalin after thoracotomy: report of four cases.
    Surgery today, 2013, Volume: 43, Issue:8

    Topics: Adenocarcinoma; Aged; Analgesics; Carcinoma, Squamous Cell; Chronic Pain; Drug Administration Schedu

2013
Mechanistic studies on delta-aminolevulinic acid uptake and efflux in a mammary adenocarcinoma cell line.
    British journal of cancer, 2003, Jul-07, Volume: 89, Issue:1

    Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; gamma-Aminobutyric Acid; Mammary Neoplasms, Animal; Mi

2003
Gamma-amino-butyric acid immunoreactivity in intramucosal colonic tumors.
    Journal of gastroenterology and hepatology, 2003, Volume: 18, Issue:9

    Topics: Adenocarcinoma; Adenoma; Colonic Neoplasms; gamma-Aminobutyric Acid; Humans; Immunohistochemistry; I

2003
Neutropenia occurring after starting gabapentin for neuropathic pain.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2004, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Amines; Analgesics; Carcinoma, Non-Small-Cell Lung; Cyclohexanecarboxylic Acids; Gab

2004
[Gabapentin mitigates neuropathic pain in cancer patients--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:8

    Topics: Adenocarcinoma; Amines; Analgesics; Bone Neoplasms; Cyclohexanecarboxylic Acids; Gabapentin; gamma-A

2007
Successful amelioration of oxaliplatin-induced hyperexcitability syndrome with the antiepileptic pregabalin in a patient with pancreatic cancer.
    Cancer chemotherapy and pharmacology, 2008, Volume: 61, Issue:3

    Topics: Adenocarcinoma; Adult; Anticonvulsants; Antimetabolites, Antineoplastic; Antineoplastic Agents; Calc

2008
Gamma-aminobutyric acid, a potential tumor suppressor for small airway-derived lung adenocarcinoma.
    Carcinogenesis, 2008, Volume: 29, Issue:10

    Topics: Adenocarcinoma; Animals; Cell Line; Cell Line, Tumor; Cricetinae; Cyclic AMP; Cyclic AMP Response El

2008
Free amino acid pools of rodent mammary tumors.
    Journal of the National Cancer Institute, 1982, Volume: 69, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Amino Acids; Animals; Arginine; Cystathionine; Fem

1982
Absence of Ki-ras mutations in exocrine pancreatic tumors from male rats chronically exposed to gabapentin.
    Mutation research, 1995, Volume: 327, Issue:1-2

    Topics: Acetates; Adenocarcinoma; Adenoma; Amines; Animals; Base Sequence; Codon; Cyclohexanecarboxylic Acid

1995
GABA content and GAD activity in colon tumors taken from patients with colon cancer or from xenografted human colon cancer cells growing as s.c. tumors in athymic nu/nu mice.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1998, Volume: 49, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Animals; Colon; Colonic Neoplasms; Female; gamma-Aminobutyric Acid; Glu

1998
GABA level and GAD activity in human and mouse normal and neoplastic mammary gland.
    Journal of experimental & clinical cancer research : CR, 1999, Volume: 18, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Animals; Biomarkers, Tumor; Breast; Breast Neoplasms

1999
[Hemiballism caused by metastasis to Luys' body].
    Revue neurologique, 1985, Volume: 141, Issue:12

    Topics: Adenocarcinoma; Aged; Basal Ganglia Diseases; Brain Neoplasms; Diencephalon; gamma-Aminobutyric Acid

1985