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gamma-aminobutyric acid and Acute Relapsing Multiple Sclerosis

gamma-aminobutyric acid has been researched along with Acute Relapsing Multiple Sclerosis in 11 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Research Excerpts

ExcerptRelevanceReference
" We report 11 MS patients with trigeminal neuralgia (TN): 6 intolerant to a therapeutic dosage of CBZ, showing serious adverse effects and subsequently treated with a combination of low-dose CBZ and gabapentin (GBP) (group 1); 5 treated with lamotrigine (LMT), showing adverse effects and subsequently treated with GBP (group 2)."7.70Low-dose gabapentin combined with either lamotrigine or carbamazepine can be useful therapies for trigeminal neuralgia in multiple sclerosis. ( Leandri, M; Mancardi, GL; Messmer Uccelli, M; Solaro, C; Uccelli, A, 2000)
" We report 11 MS patients with trigeminal neuralgia (TN): 6 intolerant to a therapeutic dosage of CBZ, showing serious adverse effects and subsequently treated with a combination of low-dose CBZ and gabapentin (GBP) (group 1); 5 treated with lamotrigine (LMT), showing adverse effects and subsequently treated with GBP (group 2)."5.31Low-dose gabapentin combined with either lamotrigine or carbamazepine can be useful therapies for trigeminal neuralgia in multiple sclerosis. ( Leandri, M; Mancardi, GL; Messmer Uccelli, M; Solaro, C; Uccelli, A, 2000)
" We report 11 MS patients with trigeminal neuralgia (TN): 6 intolerant to a therapeutic dosage of CBZ, showing serious adverse effects and subsequently treated with a combination of low-dose CBZ and gabapentin (GBP) (group 1); 5 treated with lamotrigine (LMT), showing adverse effects and subsequently treated with GBP (group 2)."3.70Low-dose gabapentin combined with either lamotrigine or carbamazepine can be useful therapies for trigeminal neuralgia in multiple sclerosis. ( Leandri, M; Mancardi, GL; Messmer Uccelli, M; Solaro, C; Uccelli, A, 2000)
"Nabilone or placebo was titrated over 4 weeks (0."2.80Nabilone as an adjunctive to gabapentin for multiple sclerosis-induced neuropathic pain: a randomized controlled trial. ( Doupe, M; Esfahani, F; Ethans, K; Galloway, K; Gomori, A; Namaka, M; Torabi, M; Turcotte, D, 2015)
"Nabilone was well tolerated, with dizziness/drowsiness most frequently reported."2.80Nabilone as an adjunctive to gabapentin for multiple sclerosis-induced neuropathic pain: a randomized controlled trial. ( Doupe, M; Esfahani, F; Ethans, K; Galloway, K; Gomori, A; Namaka, M; Torabi, M; Turcotte, D, 2015)
" We report 11 MS patients with trigeminal neuralgia (TN): 6 intolerant to a therapeutic dosage of CBZ, showing serious adverse effects and subsequently treated with a combination of low-dose CBZ and gabapentin (GBP) (group 1); 5 treated with lamotrigine (LMT), showing adverse effects and subsequently treated with GBP (group 2)."1.31Low-dose gabapentin combined with either lamotrigine or carbamazepine can be useful therapies for trigeminal neuralgia in multiple sclerosis. ( Leandri, M; Mancardi, GL; Messmer Uccelli, M; Solaro, C; Uccelli, A, 2000)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (27.27)29.6817
2010's6 (54.55)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Kantorová, E1
Hnilicová, P1
Bogner, W1
Grendár, M1
Grossmann, J1
Kováčová, S1
Hečková, E1
Strasser, B1
Čierny, D1
Zeleňák, K1
Kurča, E1
Swanberg, KM1
Prinsen, H1
DeStefano, K1
Bailey, M1
Kurada, AV1
Pitt, D1
Fulbright, RK1
Juchem, C1
Bhattacharyya, PK1
Phillips, MD1
Stone, LA1
Lowe, MJ1
Cao, G2
Edden, RAE2
Gao, F2
Li, H2
Gong, T1
Chen, W1
Liu, X1
Wang, G2
Zhao, B2
Yin, X1
Evans, AC1
Xu, J1
Li, M1
Wang, J1
Mori, F1
Nisticò, R1
Mandolesi, G1
Piccinin, S1
Mango, D1
Kusayanagi, H1
Berretta, N1
Bergami, A1
Gentile, A1
Musella, A1
Nicoletti, CG1
Nicoletti, F1
Buttari, F1
Mercuri, NB1
Martino, G1
Furlan, R1
Centonze, D1
Turcotte, D1
Doupe, M1
Torabi, M1
Gomori, A1
Ethans, K1
Esfahani, F1
Galloway, K1
Namaka, M1
Yalçınkaya, N1
Akcan, U1
Örçen, A1
Küçükali, Cİ1
Türkoğlu, R1
Kürtüncü, M1
Tüzün, E1
Solaro, C2
Boehmker, M1
Tanganelli, P1
Messmer Uccelli, M1
Uccelli, A1
Leandri, M1
Mancardi, GL1
Pozdniakov, AV1
Tiutin, LA1
Bisaga, GN1
Odinak, MM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Nabilone Use for Acute Pain in Inflammatory Bowel Disease Patients With Chronic Opioid Use Undergoing Gastrointestinal Surgery: A Single-centered Randomized Controlled Trial[NCT03422861]80 participants (Anticipated)Interventional2023-12-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for gamma-aminobutyric acid and Acute Relapsing Multiple Sclerosis

ArticleYear
Nabilone as an adjunctive to gabapentin for multiple sclerosis-induced neuropathic pain: a randomized controlled trial.
    Pain medicine (Malden, Mass.), 2015, Volume: 16, Issue:1

    Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Double-Blind Method; Dronabinol; Female; Gab

2015
Pregabalin for treating paroxysmal painful symptoms in multiple sclerosis: a pilot study.
    Journal of neurology, 2009, Volume: 256, Issue:10

    Topics: Adult; Aged; Analgesics; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Multiple Sclero

2009

Other Studies

9 other studies available for gamma-aminobutyric acid and Acute Relapsing Multiple Sclerosis

ArticleYear
Neurocognitive performance in relapsing-remitting multiple sclerosis patients is associated with metabolic abnormalities of the thalamus but not the hippocampus- GABA-edited 1H MRS study.
    Neurological research, 2022, Volume: 44, Issue:1

    Topics: gamma-Aminobutyric Acid; Hippocampus; Humans; Magnetic Resonance Imaging; Multiple Sclerosis; Multip

2022
In vivo evidence of differential frontal cortex metabolic abnormalities in progressive and relapsing-remitting multiple sclerosis.
    NMR in biomedicine, 2021, Volume: 34, Issue:11

    Topics: Adult; Aged; Aspartic Acid; Choline; Female; Frontal Lobe; gamma-Aminobutyric Acid; Glutamine; Gluta

2021
Activation volume vs BOLD signal change as measures of fMRI activation - Its impact on GABA - fMRI activation correlation.
    Magnetic resonance imaging, 2017, Volume: 42

    Topics: Adult; Case-Control Studies; Female; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Ma

2017
Reduced GABA levels correlate with cognitive impairment in patients with relapsing-remitting multiple sclerosis.
    European radiology, 2018, Volume: 28, Issue:3

    Topics: Adult; Brain; Case-Control Studies; Cognitive Dysfunction; Female; gamma-Aminobutyric Acid; Gyrus Ci

2018
Altered hippocampal GABA and glutamate levels and uncoupling from functional connectivity in multiple sclerosis.
    Hippocampus, 2018, Volume: 28, Issue:11

    Topics: Adult; Brain Mapping; Cognition; Female; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Humans

2018
Interleukin-1β promotes long-term potentiation in patients with multiple sclerosis.
    Neuromolecular medicine, 2014, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Animals; Encephalomyelitis, Autoimmune, Experimental; Female; gamma-Aminobutyric

2014
Reduced fecal GABA levels in multiple sclerosis patients.
    Multiple sclerosis and related disorders, 2016, Volume: 9

    Topics: Body Mass Index; Disability Evaluation; Enzyme-Linked Immunosorbent Assay; Feces; gamma-Aminobutyric

2016
Low-dose gabapentin combined with either lamotrigine or carbamazepine can be useful therapies for trigeminal neuralgia in multiple sclerosis.
    European neurology, 2000, Volume: 44, Issue:1

    Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Res

2000
[Proton magnetic-resonance spectroscopy in remitting and secondary-progressive multiple sclerosis].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2001, Volume: 101, Issue:4

    Topics: Adolescent; Adult; Aspartic Acid; Brain; Choline; Creatine; Demyelinating Diseases; Female; gamma-Am

2001