gallopamil and Necrosis
gallopamil has been researched along with Necrosis in 8 studies
Gallopamil: Coronary vasodilator that is an analog of iproveratril (VERAPAMIL) with one more methoxy group on the benzene ring.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"To determine whether gallopamil (D600), a methoxy derivative of verapamil, administered immediately before coronary artery reperfusion reduces the extent of myocardial hemorrhage and necrosis, the left anterior descending coronary artery was occluded for 3 h and reperfused for 3 h in anesthetized, open-chest dogs." | 7.68 | Reduction in myocardial hemorrhage and the extent of necrosis by gallopamil (D600) in dogs with coronary artery reperfusion. ( Endo, T; Hayakawa, H; Maroko, PR; Sato, N, 1991) |
"To examine whether gallopamil (D600), a methoxy derivative of verapamil, has sustained beneficial effects on the ischemic myocardium, its effects on the size of myocardial infarction determined 6 hours (protocol 1) and 24 hours (protocol 2) after left anterior descending coronary artery occlusion were compared in anesthetized, open-chest dogs." | 7.68 | Sustained beneficial effects of gallopamil (D600) on size of myocardial infarction 24 hours after coronary artery occlusion in dogs. ( Endo, T; Hayakawa, H; Kiuchi, K; Maroko, PR; Sato, N, 1990) |
"To determine whether gallopamil (D600), a methoxy derivative of verapamil, administered immediately before coronary artery reperfusion reduces the extent of myocardial hemorrhage and necrosis, the left anterior descending coronary artery was occluded for 3 h and reperfused for 3 h in anesthetized, open-chest dogs." | 3.68 | Reduction in myocardial hemorrhage and the extent of necrosis by gallopamil (D600) in dogs with coronary artery reperfusion. ( Endo, T; Hayakawa, H; Maroko, PR; Sato, N, 1991) |
"To examine whether gallopamil (D600), a methoxy derivative of verapamil, has sustained beneficial effects on the ischemic myocardium, its effects on the size of myocardial infarction determined 6 hours (protocol 1) and 24 hours (protocol 2) after left anterior descending coronary artery occlusion were compared in anesthetized, open-chest dogs." | 3.68 | Sustained beneficial effects of gallopamil (D600) on size of myocardial infarction 24 hours after coronary artery occlusion in dogs. ( Endo, T; Hayakawa, H; Kiuchi, K; Maroko, PR; Sato, N, 1990) |
"Perfusion of the isolated rat heart with Krebs-Henseleit solution containing adrenochrome (25 or 50 mg/l), and oxidation product of catechalmines, resulted in contractile failure and myocardial necrosis." | 3.66 | Protection against adrenochrome-induced myocardial damage by various pharmacological interventions. ( Beamish, RE; Dhalla, NS; Singal, PK; Taam, GM; Yates, JC, 1980) |
"The effect of inhibiting isoprenaline-induced intracellular calcium accumulation on the degree of damage produced in the rat myocardium by this amine has been investigated by simultaneously dosing rats with the calcium antagonistic drug D600." | 1.26 | The effect of a calcium antagonist (D600) on isoprenaline-induced myocardial necrosis in the rat. ( Powell, T; Rowles, PM; Steen, E; Woolf, N, 1979) |
Research
Studies (8)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 5 (62.50) | 18.7374 |
1990's | 3 (37.50) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Yates, JC | 1 |
Taam, GM | 1 |
Singal, PK | 1 |
Beamish, RE | 1 |
Dhalla, NS | 1 |
Steen, E | 1 |
Woolf, N | 1 |
Powell, T | 1 |
Rowles, PM | 1 |
Leder, O | 1 |
Strubelt, O | 1 |
Hoffmann, A | 1 |
Siegers, CP | 1 |
Sierra-Callejas, JL | 1 |
Sigel, H | 1 |
Janke, J | 1 |
Fleckenstein, A | 1 |
Endo, T | 2 |
Sato, N | 2 |
Hayakawa, H | 2 |
Maroko, PR | 3 |
Kiuchi, K | 1 |
Faria, DB | 1 |
Goncalves, FR | 1 |
Other Studies
8 other studies available for gallopamil and Necrosis
Article | Year |
---|---|
Protection against adrenochrome-induced myocardial damage by various pharmacological interventions.
Topics: Adrenochrome; Animals; Antihypertensive Agents; Cardiomyopathies; Gallopamil; Heart; In Vitro Techni | 1980 |
The effect of a calcium antagonist (D600) on isoprenaline-induced myocardial necrosis in the rat.
Topics: Animals; Calcium; Cardiomyopathies; Gallopamil; Isoproterenol; Male; Myocardium; Necrosis; Rats; Ver | 1979 |
[Microscopic quantification of myocardial necroses in experimental cardiology].
Topics: Animals; Calcitonin; Dose-Response Relationship, Drug; Gallopamil; Histological Techniques; Isoprote | 1976 |
On the pathogenesis of cardiac necroses induced by theophylline and caffeine.
Topics: Animals; Blood Pressure; Caffeine; Calcium; Gallopamil; Heart; Heart Rate; Isoproterenol; Male; Myoc | 1976 |
Restriction of isoproterenol-induced myocardial Ca uptake and necrotization in rats by a new Ca-antagonistic compound (ethyl-4-(3,4,5-trimethoxycinnamoyl) piperazinyl acetate (Vascordil)).
Topics: Animals; Biological Transport; Calcium; Cardiomyopathies; Cinnamates; Dose-Response Relationship, Dr | 1975 |
Reduction in myocardial hemorrhage and the extent of necrosis by gallopamil (D600) in dogs with coronary artery reperfusion.
Topics: Animals; Autoradiography; Blood Pressure; Coronary Vessels; Dogs; Female; Gallopamil; Heart Diseases | 1991 |
Sustained beneficial effects of gallopamil (D600) on size of myocardial infarction 24 hours after coronary artery occlusion in dogs.
Topics: Animals; Autoradiography; Dogs; Female; Gallopamil; Hemodynamics; Male; Myocardial Infarction; Myoca | 1990 |
Three-dimensional analysis of infarct size reduction after administration of gallopamil in dogs.
Topics: Animals; Autoradiography; Coronary Disease; Dogs; Female; Gallopamil; Hemodynamics; Male; Models, Bi | 1990 |