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gallopamil and Myocardial Ischemia

gallopamil has been researched along with Myocardial Ischemia in 15 studies

Gallopamil: Coronary vasodilator that is an analog of iproveratril (VERAPAMIL) with one more methoxy group on the benzene ring.

Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).

Research Excerpts

ExcerptRelevanceReference
"Gallopamil is a methoxy derivative of verapamil."2.39Gallopamil. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in ischaemic heart disease. ( Benfield, P; Brogden, RN, 1994)
"Gallopamil was then discontinued."1.29[Ventricular fibrillation and silent myocardial ischemia in a patient without anatomic heart disease]. ( Alt, E; Barthel, P; Meisner, H; Schmidt, G; Schmitt, C; Schömig, A, 1993)
"Nifedipine was the most effective with only 5 +/- 2% reduction in blood flow after five ischaemic episodes, whereas reduction of myocardial blood flow was 30 +/- 4% in the presence of gallopamil."1.29Preservation of myocardial blood flow by calcium antagonists does not prevent attenuation of regional myocardial function after repetitive brief periods of myocardial ischaemia in the rat heart. ( Amann, K; Kübler, W; Parekh, N; Rauch, B; Tiefenbacher, CP; Tillmanns, H; Zimmermann, R, 1995)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's14 (93.33)18.2507
2000's1 (6.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, PS1
Wu, TJ1
Ting, CT1
Karagueuzian, HS1
Garfinkel, A1
Lin, SF1
Weiss, JN1
Brogden, RN1
Benfield, P1
Acanfora, D1
Odierna, L1
De Caprio, L1
Longobardi, G1
Rengo, C1
Guerra, N1
Furgi, G1
Bollella, OF1
Picone, C1
Rengo, F1
Massoudy, P1
Becker, BF1
Seligmann, C1
Gerlach, E1
Mitrovic, V1
Oehm, E1
Minge, C1
Thürmann, P1
Schlepper, M2
Perticone, F1
Borelli, DA1
Pugliese, F1
Maio, R1
Costa, R1
Cosco, C1
Ceravolo, R1
Mattioli, PL1
Molinero De Miguel, E1
Salcedo Arruti, A1
Sagastagoitia Gorostiza, JD1
Iriarte Ezkurdia, MM1
Fernandez Vidal, P1
Velasco Quintana, J1
Garrido García, J1
Simonelli, P1
Papa, A1
Macciocchi, B1
Auriemma, F1
Vetrano, A1
Scaletta Romeo di Santillo, M1
Ceriello, A1
Schmitt, C1
Barthel, P1
Schmidt, G1
Alt, E1
Meisner, H1
Schömig, A1
Simarro, E1
Rodríguez, MA1
Bayón, J1
Lastra, JA1
Prieto, P1
Suárez, G1
García Porrero, E1
Fernández, R1
Garrido, J1
Velasco, J1
Tiefenbacher, CP1
Zimmermann, R2
Parekh, N1
Amann, K1
Tillmanns, H2
Rauch, B2
Kübler, W2
Kapp, M1
Grethe, U1
Neumann, FJ1
Schlumpp, K1
Bubeck, B1
Carboni, GP1
Saltarocchi, ML1
Risa, AL1
Scardovi, AB1
Zanchi, E1
Prati, PL1
Rettig, GF1
Jakob, M1
Koch, HP1

Reviews

2 reviews available for gallopamil and Myocardial Ischemia

ArticleYear
A tale of two fibrillations.
    Circulation, 2003, Nov-11, Volume: 108, Issue:19

    Topics: Action Potentials; Animals; Calcium Channel Blockers; Death, Sudden, Cardiac; Electrocardiography; G

2003
Gallopamil. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in ischaemic heart disease.
    Drugs, 1994, Volume: 47, Issue:1

    Topics: Animals; Gallopamil; Humans; Myocardial Ischemia

1994

Trials

10 trials available for gallopamil and Myocardial Ischemia

ArticleYear
Age-response effectiveness of gallopamil for the treatment of myocardial exertional ischemia. A medium-term randomized cross-over double-blind placebo-controlled trial.
    Aging (Milan, Italy), 1995, Volume: 7, Issue:2

    Topics: Adult; Age Distribution; Aged; Angiography; Coronary Circulation; Cross-Over Studies; Double-Blind M

1995
[Anti-ischemia effects of gallopamil and esmolol in an intra-individual comparison in patients with coronary heart disease].
    Zeitschrift fur Kardiologie, 1994, Volume: 83, Issue:6

    Topics: Adrenergic beta-Antagonists; Aged; Aldosterone; Atrial Natriuretic Factor; Coronary Angiography; Cor

1994
[The anti-ischemic effect of phosphodiesterase III inhibitors].
    Zeitschrift fur Kardiologie, 1994, Volume: 83 Suppl 2

    Topics: Administration, Oral; Calcium; Coronary Circulation; Coronary Disease; Cyclic AMP; Dose-Response Rel

1994
[An ergometric cross-over evaluation of the anti-ischemic efficacy of amlodipine and gallopamil in stable angina of effort].
    Cardiologia (Rome, Italy), 1993, Volume: 38, Issue:7

    Topics: Adult; Aged; Amlodipine; Analysis of Variance; Angina Pectoris; Exercise Test; Female; Gallopamil; H

1993
Comparative study of gallopamil versus nifedipine in patients with ischemic heart disease.
    International journal of cardiology, 1993, Jul-01, Volume: 40, Issue:2

    Topics: Adult; Aged; Analysis of Variance; Blood Pressure; Double-Blind Method; Electrocardiography; Exercis

1993
[Treatment of ischemic heart disease in the elderly. Comparison of diltiazem, verapamil and gallopamil].
    Minerva cardioangiologica, 1993, Volume: 41, Issue:5

    Topics: Age Factors; Aged; Angina Pectoris; Coronary Angiography; Coronary Disease; Diltiazem; Drug Evaluati

1993
[The effect of gallopamil and propranolol in patients with ischemic cardiopathy and moderate depression of ventricular function].
    Revista espanola de cardiologia, 1995, Volume: 48, Issue:11

    Topics: Adrenergic beta-Antagonists; Aged; Calcium Channel Blockers; Cross-Over Studies; Double-Blind Method

1995
Reduction of myocardial ischemia by gallopamil: a dual-isotope study with thallium-201 and iodine-123 phenylpentadecanoic acid.
    Journal of cardiovascular pharmacology, 1992, Volume: 20 Suppl 7

    Topics: Algorithms; Coronary Circulation; Double-Blind Method; Female; Gallopamil; Humans; Iodine Radioisoto

1992
Combined gallopamil and isosorbide-5-mononitrate in "mixed" angina pectoris.
    Journal of cardiovascular pharmacology, 1992, Volume: 20 Suppl 7

    Topics: Aged; Angina Pectoris; Double-Blind Method; Drug Therapy, Combination; Electrocardiography, Ambulato

1992
[The anti-ischemic effect of gallopamil-retard in comparison with nifedipine-retard in stable angina pectoris].
    Zeitschrift fur Kardiologie, 1992, Volume: 81, Issue:10

    Topics: Aged; Angina Pectoris; Blood Pressure; Coronary Disease; Delayed-Action Preparations; Dose-Response

1992

Other Studies

3 other studies available for gallopamil and Myocardial Ischemia

ArticleYear
Preischaemic as well as postischaemic application of a calcium antagonist affords cardioprotection in the isolated guinea pig heart.
    Cardiovascular research, 1995, Volume: 29, Issue:4

    Topics: Animals; Coronary Circulation; Gallopamil; Glutathione; Guinea Pigs; Heart; Lactates; Lactic Acid; L

1995
[Ventricular fibrillation and silent myocardial ischemia in a patient without anatomic heart disease].
    Deutsche medizinische Wochenschrift (1946), 1993, Oct-15, Volume: 118, Issue:41

    Topics: Adult; Cardiac Catheterization; Defibrillators, Implantable; Electrocardiography, Ambulatory; Gallop

1993
Preservation of myocardial blood flow by calcium antagonists does not prevent attenuation of regional myocardial function after repetitive brief periods of myocardial ischaemia in the rat heart.
    European heart journal, 1995, Volume: 16, Issue:8

    Topics: Animals; Blood Flow Velocity; Calcium Channel Blockers; Female; Gallopamil; Infusions, Intravenous;

1995