gallopamil has been researched along with Asthma, Bronchial in 9 studies
Gallopamil: Coronary vasodilator that is an analog of iproveratril (VERAPAMIL) with one more methoxy group on the benzene ring.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We studied the comparative modification of histamine- and methacholine-induced bronchoconstriction by a calcium antagonist, gallopamil, in 8 subjects with bronchial asthma." | 9.07 | Modification of histamine- and methacholine-induced bronchoconstriction by calcium antagonist gallopamil in asthmatics. ( Ahmed, T; Danta, I, 1992) |
| "The effect of gallopamil on the late-phase response to inhaled allergen was evaluated in six young adults with allergic asthma in a crossover manner." | 9.07 | The effect of inhaled gallopamil, a potent calcium channel blocker, on the late-phase response in subjects with allergic asthma. ( Harman, E; Hendeles, L; Hoppe, M, 1992) |
| "RWJ 22108 (N-benzyl-N-methylaminoethyl 9-(2-chloro-6-fluorophenyl)-2,3,4,5,6,9-hexahydro-7-methyl-1, 1-dioxothiacyclohepteno-[3,2-b]pyridine-8-carboxylate) is a new bronchoselective calcium entry blocker with potential use as an antiasthmatic agent." | 7.68 | Experimental antiasthmatic activity of RWJ 22108: a bronchoselective calcium entry blocker. ( Ahmed, T; Anderson, DW; Capetola, RJ; Dodd, JH; Kirchner, T; Moore, JB; Ritchie, DM, 1993) |
| "We conducted a double-blind, randomized, placebo-controlled study to evaluate the effect of gallopamil on airway remodeling in patients with severe asthma." | 5.20 | Calcium channel blocker reduces airway remodeling in severe asthma. A proof-of-concept study. ( Begueret, H; Berger, P; Dos Santos, P; Dournes, G; Dupin, I; Girodet, PO; Laurent, F; Marthan, R; Montaudon, M; Ozier, A; Thumerel, M; Trian, T, 2015) |
| "We studied the comparative modification of histamine- and methacholine-induced bronchoconstriction by a calcium antagonist, gallopamil, in 8 subjects with bronchial asthma." | 5.07 | Modification of histamine- and methacholine-induced bronchoconstriction by calcium antagonist gallopamil in asthmatics. ( Ahmed, T; Danta, I, 1992) |
| "The effect of gallopamil on the late-phase response to inhaled allergen was evaluated in six young adults with allergic asthma in a crossover manner." | 5.07 | The effect of inhaled gallopamil, a potent calcium channel blocker, on the late-phase response in subjects with allergic asthma. ( Harman, E; Hendeles, L; Hoppe, M, 1992) |
| "The present study was conducted to determine the duration of the positive effect of oral diltiazem and inhaled gallopamil in mild asthmatic volunteers, ages 18-37 years, with a history of exercise-induced asthma and a 25-56% decrease in FEV1 after a standardized exercise challenge." | 5.06 | Duration of protection of calcium channel blockers against exercise-induced bronchospasm: comparison of oral diltiazem and inhaled gallopamil. ( Harman, E; Hendeles, L; Massey, KL, 1988) |
| "To determine if there is a dose-response relationship for calcium channel blockers in preventing experimentally induced bronchoconstriction, we evaluated the effects of inhaled gallopamil (D600), a potent methoxy derivative of verapamil, on airway reactivity to methacholine and exercise in volunteers with mild asthma." | 5.06 | Dose response of inhaled gallopamil (D600), a calcium channel blocker, in attenuating airway reactivity to methacholine and exercise. ( Ahrens, R; Harman, E; Hendeles, L; Hill, M; Massey, KL; Rutledge, DR, 1988) |
| "RWJ 22108 (N-benzyl-N-methylaminoethyl 9-(2-chloro-6-fluorophenyl)-2,3,4,5,6,9-hexahydro-7-methyl-1, 1-dioxothiacyclohepteno-[3,2-b]pyridine-8-carboxylate) is a new bronchoselective calcium entry blocker with potential use as an antiasthmatic agent." | 3.68 | Experimental antiasthmatic activity of RWJ 22108: a bronchoselective calcium entry blocker. ( Ahmed, T; Anderson, DW; Capetola, RJ; Dodd, JH; Kirchner, T; Moore, JB; Ritchie, DM, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Beaufils, F | 1 |
| Esteves, P | 1 |
| Enaud, R | 1 |
| Germande, O | 1 |
| Celle, A | 1 |
| Marthan, R | 2 |
| Trian, T | 2 |
| Fayon, M | 1 |
| Berger, P | 2 |
| Girodet, PO | 1 |
| Dournes, G | 1 |
| Thumerel, M | 1 |
| Begueret, H | 1 |
| Dos Santos, P | 1 |
| Ozier, A | 1 |
| Dupin, I | 1 |
| Montaudon, M | 1 |
| Laurent, F | 1 |
| Sumino, K | 1 |
| Sheshadri, A | 1 |
| Castro, M | 1 |
| Ritchie, DM | 1 |
| Kirchner, T | 1 |
| Moore, JB | 1 |
| Dodd, JH | 1 |
| Ahmed, T | 3 |
| Anderson, DW | 1 |
| Capetola, RJ | 1 |
| Danta, I | 2 |
| Hoppe, M | 1 |
| Harman, E | 3 |
| Hendeles, L | 3 |
| Kim, CS | 1 |
| Massey, KL | 2 |
| Hill, M | 1 |
| Rutledge, DR | 1 |
| Ahrens, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Gallopamil on Bronchial Smooth Muscle Remodelling in Severe Asthma: a Double Blind Study.[NCT00896428] | Phase 2 | 31 participants (Actual) | Interventional | 2009-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 trials available for gallopamil and Asthma, Bronchial
| Article | Year |
|---|---|
Mitochondria are involved in bronchial smooth muscle remodeling in severe preschool wheezers.
Topics: Airway Remodeling; Asthma; Bronchi; Calcium Signaling; Cells, Cultured; Child, Preschool; Female; Ga | 2021 |
Calcium channel blocker reduces airway remodeling in severe asthma. A proof-of-concept study.
Topics: Airway Remodeling; Asthma; Bronchography; Bronchoscopy; Calcium Channel Blockers; Double-Blind Metho | 2015 |
Modification of histamine- and methacholine-induced bronchoconstriction by calcium antagonist gallopamil in asthmatics.
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Dose-Response Relationship, Drug; D | 1992 |
The effect of inhaled gallopamil, a potent calcium channel blocker, on the late-phase response in subjects with allergic asthma.
Topics: Administration, Inhalation; Adolescent; Adult; Allergens; Asthma; Bronchial Provocation Tests; Drug | 1992 |
Inhibition of antigen-induced bronchoconstriction by a new calcium antagonist, gallopamil: comparison with cromolyn sodium.
Topics: Adult; Airway Resistance; Asthma; Bronchial Spasm; Bronchodilator Agents; Cromolyn Sodium; Dose-Resp | 1988 |
Duration of protection of calcium channel blockers against exercise-induced bronchospasm: comparison of oral diltiazem and inhaled gallopamil.
Topics: Administration, Inhalation; Administration, Oral; Adolescent; Adult; Asthma; Asthma, Exercise-Induce | 1988 |
Dose response of inhaled gallopamil (D600), a calcium channel blocker, in attenuating airway reactivity to methacholine and exercise.
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Dose-Response Relationship, Drug; Doubl | 1988 |
2 other studies available for gallopamil and Asthma, Bronchial
| Article | Year |
|---|---|
Calcium channel blocker reduces airway remodeling-or does it?
Topics: Airway Remodeling; Asthma; Calcium Channel Blockers; Female; Gallopamil; Humans; Male | 2015 |
Experimental antiasthmatic activity of RWJ 22108: a bronchoselective calcium entry blocker.
Topics: Airway Obstruction; Airway Resistance; Animals; Antigens; Asthma; Bronchial Spasm; Bronchoconstricti | 1993 |