gallic acid has been researched along with Protein Aggregation, Pathological in 4 studies
gallate : A trihydroxybenzoate that is the conjugate base of gallic acid.
Protein Aggregation, Pathological: A biochemical phenomenon in which misfolded proteins aggregate either intra- or extracellularly. Triggered by factors such as MUTATION; POST-TRANSLATIONAL MODIFICATIONS, and environmental stress, it is generally associated with ALZHEIMER DISEASE; PARKINSON DISEASE; HUNTINGTON DISEASE; and TYPE 2 DIABETES MELLITUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gallic acid has been shown to both modulate factors leading to the onset of neurodegenerative disorders, as well as directly inhibit amyloid formation." | 1.56 | Gallic acid oxidation products alter the formation pathway of insulin amyloid fibrils. ( Sakalauskas, A; Smirnovas, V; Ziaunys, M, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pérez-Areales, FJ | 1 |
| Di Pietro, O | 1 |
| Espargaró, A | 1 |
| Vallverdú-Queralt, A | 1 |
| Galdeano, C | 1 |
| Ragusa, IM | 1 |
| Viayna, E | 1 |
| Guillou, C | 1 |
| Clos, MV | 1 |
| Pérez, B | 1 |
| Sabaté, R | 1 |
| Lamuela-Raventós, RM | 1 |
| Luque, FJ | 1 |
| Muñoz-Torrero, D | 1 |
| Silva, T | 1 |
| Mohamed, T | 1 |
| Shakeri, A | 1 |
| Rao, PPN | 1 |
| Soares da Silva, P | 1 |
| Remião, F | 1 |
| Borges, F | 1 |
| Li, X | 1 |
| Zhang, X | 1 |
| Xing, R | 1 |
| Qi, F | 1 |
| Dong, J | 1 |
| Li, D | 1 |
| Tian, X | 1 |
| Yu, B | 1 |
| Huang, M | 1 |
| Zhang, L | 1 |
| Yuan, X | 1 |
| Yang, Y | 1 |
| Wu, H | 1 |
| Zang, L | 1 |
| Mao, X | 1 |
| Sui, R | 1 |
| Sakalauskas, A | 1 |
| Ziaunys, M | 1 |
| Smirnovas, V | 1 |
4 other studies available for gallic acid and Protein Aggregation, Pathological
| Article | Year |
|---|---|
Shogaol-huprine hybrids: dual antioxidant and anticholinesterase agents with β-amyloid and tau anti-aggregating properties.
Topics: Acetylcholinesterase; Aminoquinolines; Amyloid beta-Peptides; Antioxidants; Catechols; Cholinesteras | 2014 |
Repurposing nitrocatechols: 5-Nitro-α-cyanocarboxamide derivatives of caffeic acid and caffeic acid phenethyl ester effectively inhibit aggregation of tau-derived hexapeptide AcPHF6.
Topics: Caffeic Acids; Catechols; Chelating Agents; Copper; Drug Design; Nitro Compounds; Peptides; Phenylet | 2019 |
Syringic acid demonstrates promising protective effect against tau fibrillization and cytotoxicity through regulation of endoplasmic reticulum stress-mediated pathway as a prelude to Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid; Apoptosis; Endoplasmic Reticulum Stress; Gallic Acid; Humans; Kinetics; | 2021 |
Gallic acid oxidation products alter the formation pathway of insulin amyloid fibrils.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Amyloidogenic Proteins; Gallic Acid; Humans; Insu | 2020 |