gallic acid has been researched along with Prostatic Neoplasms in 18 studies
gallate : A trihydroxybenzoate that is the conjugate base of gallic acid.
Prostatic Neoplasms: Tumors or cancer of the PROSTATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In vitro treatment of HCT-116 colon cancer cells with 3,4-DHPAA and EGCG exhibited an additive antiproliferative effect, while methylation of 3,4-DHPAA was significantly decreased." | 2.78 | Phenolic acid concentrations in plasma and urine from men consuming green or black tea and potential chemopreventive properties for colon cancer. ( Abgaryan, N; Aronson, WJ; Carpenter, CL; de Oliveira, DM; Heber, D; Henning, SM; Lee, RP; Vicinanza, R; Wang, P; Zhang, Y, 2013) |
| "Gallic acid (GA) is a polyhydroxy phenolic compound which can inhibit the growth of cancer cells." | 1.43 | The reduction of IL-6 gene expression, pAKT, pERK1/2, pSTAT3 signaling pathways and invasion activity by gallic acid in prostate cancer PC3 cells. ( Ghatreh-Samani, K; Heidarian, E; Keloushadi, M; Valipour, P, 2016) |
| "Gallic acid (GA) is a natural polyphenol, and we tested its in-vitro cytotoxicity after 24 h in prostate cancer LNCaP cells." | 1.38 | Autoxidation of gallic acid induces ROS-dependent death in human prostate cancer LNCaP cells. ( Agharahimi, M; Badisa, RB; Goodman, CB; Mazzio, E; Oriaku, ET; Russell, LH; Zhu, ZP, 2012) |
| "Gallic acid (GA) has been demonstrated to possess multiple biological activities including anticancer function." | 1.37 | Gallic acid suppresses the migration and invasion of PC-3 human prostate cancer cells via inhibition of matrix metalloproteinase-2 and -9 signaling pathways. ( Chiang, JH; Chueh, FS; Chung, JG; Huang, AC; Lin, HY; Liu, KC; Lu, CC; Meng, M; Wu, PP; Yang, JS, 2011) |
| "Prostate cancer is one of the most commonly diagnosed solid malignancies among US men." | 1.37 | Differential cytotoxicity of triphala and its phenolic constituent gallic acid on human prostate cancer LNCap and normal cells. ( Agharahimi, M; Badisa, RB; Goodman, CB; Mazzio, E; Millington, DJ; Russell, LH; Zhu, ZP, 2011) |
| "It is cytotoxic to DU145 prostate cancer cells, through generation of reactive oxygen species (ROS) and mitochondria-mediated apoptosis, which were reversed by antioxidants catalase and N-acetylcysteine." | 1.35 | Gallic acid, a major component of Toona sinensis leaf extracts, contains a ROS-mediated anti-cancer activity in human prostate cancer cells. ( Chang, FR; Chen, CC; Chen, HM; Chia, YC; Hsieh, YC; Hsu, HK; Wu, YC; Yuan, SS, 2009) |
| "Gallic acid treatment of DU145 cells resulted in a strong cell growth inhibition, cell cycle arrest, and apoptotic death in a dose- and time-dependent manner, together with a decrease in cyclin-dependent kinases and cyclins but strong induction in Cip1/p21." | 1.33 | Gallic acid causes inactivating phosphorylation of cdc25A/cdc25C-cdc2 via ATM-Chk2 activation, leading to cell cycle arrest, and induces apoptosis in human prostate carcinoma DU145 cells. ( Agarwal, C; Agarwal, R; Tyagi, A, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (44.44) | 29.6817 |
| 2010's | 9 (50.00) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Jang, YG | 1 |
| Ko, EB | 1 |
| Choi, KC | 1 |
| Suda, M | 1 |
| Katoh, M | 1 |
| Toda, K | 1 |
| Matsumoto, K | 1 |
| Kawaguchi, K | 1 |
| Kawahara, S | 1 |
| Hattori, Y | 1 |
| Fujii, H | 1 |
| Makabe, H | 1 |
| Heidarian, E | 1 |
| Keloushadi, M | 1 |
| Ghatreh-Samani, K | 1 |
| Valipour, P | 1 |
| Kaur, M | 1 |
| Velmurugan, B | 1 |
| Rajamanickam, S | 2 |
| Agarwal, R | 4 |
| Agarwal, C | 4 |
| Chen, HM | 1 |
| Wu, YC | 1 |
| Chia, YC | 1 |
| Chang, FR | 1 |
| Hsu, HK | 1 |
| Hsieh, YC | 1 |
| Chen, CC | 1 |
| Yuan, SS | 1 |
| Reddivari, L | 1 |
| Vanamala, J | 1 |
| Safe, SH | 1 |
| Miller, JC | 1 |
| Cirillo, G | 1 |
| Kraemer, K | 1 |
| Fuessel, S | 1 |
| Puoci, F | 1 |
| Curcio, M | 1 |
| Spizzirri, UG | 1 |
| Altimari, I | 1 |
| Iemma, F | 1 |
| Liu, KC | 2 |
| Huang, AC | 2 |
| Wu, PP | 1 |
| Lin, HY | 2 |
| Chueh, FS | 2 |
| Yang, JS | 2 |
| Lu, CC | 2 |
| Chiang, JH | 2 |
| Meng, M | 2 |
| Chung, JG | 2 |
| Ho, HC | 1 |
| Ji, BC | 1 |
| Russell, LH | 2 |
| Mazzio, E | 2 |
| Badisa, RB | 2 |
| Zhu, ZP | 2 |
| Agharahimi, M | 2 |
| Millington, DJ | 1 |
| Goodman, CB | 2 |
| Oriaku, ET | 1 |
| Henning, SM | 1 |
| Wang, P | 1 |
| Abgaryan, N | 1 |
| Vicinanza, R | 1 |
| de Oliveira, DM | 1 |
| Zhang, Y | 1 |
| Lee, RP | 1 |
| Carpenter, CL | 1 |
| Aronson, WJ | 1 |
| Heber, D | 1 |
| Lee, HH | 1 |
| Ho, CT | 1 |
| Lin, JK | 1 |
| Floryk, D | 1 |
| Huberman, E | 1 |
| Veluri, R | 1 |
| Singh, RP | 1 |
| Liu, Z | 1 |
| Thompson, JA | 1 |
| Tyagi, A | 1 |
| Actis-Goretta, L | 1 |
| Romanczyk, LJ | 1 |
| Rodriguez, CA | 1 |
| Kwik-Uribe, C | 1 |
| Keen, CL | 1 |
| Raina, K | 1 |
| Deep, G | 1 |
| Singh, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact of Non Digestible Carbohydrate on Production of Phenolic Acids From Strawberry Juice[NCT03383809] | 15 participants (Actual) | Interventional | 2017-04-28 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for gallic acid and Prostatic Neoplasms
| Article | Year |
|---|---|
Phenolic acid concentrations in plasma and urine from men consuming green or black tea and potential chemopreventive properties for colon cancer.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy | 2013 |
17 other studies available for gallic acid and Prostatic Neoplasms
| Article | Year |
|---|---|
Gallic acid, a phenolic acid, hinders the progression of prostate cancer by inhibition of histone deacetylase 1 and 2 expression.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Disease Progression; Down-Regulation; Gallic Acid; | 2020 |
Syntheses of procyanidin B2 and B3 gallate derivatives using equimolar condensation mediated by Yb(OTf)3 and their antitumor activities.
Topics: Antineoplastic Agents; Biflavonoids; Catechin; Cell Line, Tumor; Gallic Acid; Humans; Male; Mesylate | 2013 |
The reduction of IL-6 gene expression, pAKT, pERK1/2, pSTAT3 signaling pathways and invasion activity by gallic acid in prostate cancer PC3 cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Dose-Resp | 2016 |
Gallic acid, an active constituent of grape seed extract, exhibits anti-proliferative, pro-apoptotic and anti-tumorigenic effects against prostate carcinoma xenograft growth in nude mice.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Gallic A | 2009 |
Gallic acid, a major component of Toona sinensis leaf extracts, contains a ROS-mediated anti-cancer activity in human prostate cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Cycle; C | 2009 |
The bioactive compounds alpha-chaconine and gallic acid in potato extracts decrease survival and induce apoptosis in LNCaP and PC3 prostate cancer cells.
Topics: Antigens, CD1; Apoptosis; Caspases; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase In | 2010 |
Biological activity of a gallic acid-gelatin conjugate.
Topics: Acetylcholinesterase; Alzheimer Disease; Antineoplastic Agents; Antioxidants; Carcinoma, Renal Cell; | 2010 |
Gallic acid suppresses the migration and invasion of PC-3 human prostate cancer cells via inhibition of matrix metalloproteinase-2 and -9 signaling pathways.
Topics: Cell Adhesion; Cell Line, Tumor; Cell Movement; Dose-Response Relationship, Drug; Gallic Acid; Gene | 2011 |
Gallic acid provokes DNA damage and suppresses DNA repair gene expression in human prostate cancer PC-3 cells.
Topics: Apoptosis; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line, Tumor; Cell Survi | 2013 |
Differential cytotoxicity of triphala and its phenolic constituent gallic acid on human prostate cancer LNCap and normal cells.
Topics: Apoptosis; Cells, Cultured; Dihydrotestosterone; Gallic Acid; Humans; Male; Plant Extracts; Prostate | 2011 |
Autoxidation of gallic acid induces ROS-dependent death in human prostate cancer LNCaP cells.
Topics: Acetylcysteine; Apoptosis; Caspases; Cell Line, Tumor; Cytochromes c; Gallic Acid; Glutathione; Huma | 2012 |
Theaflavin-3,3'-digallate and penta-O-galloyl-beta-D-glucose inhibit rat liver microsomal 5alpha-reductase activity and the expression of androgen receptor in LNCaP prostate cancer cells.
Topics: Animals; Biflavonoids; Catechin; Cholestenone 5 alpha-Reductase; Gallic Acid; Glucose; Kinetics; Liv | 2004 |
Differentiation of androgen-independent prostate cancer PC-3 cells is associated with increased nuclear factor-kappaB activity.
Topics: Androgens; Antibiotics, Antineoplastic; Apigenin; Apoptosis; Biological Transport; Calcium Channel B | 2005 |
Fractionation of grape seed extract and identification of gallic acid as one of the major active constituents causing growth inhibition and apoptotic death of DU145 human prostate carcinoma cells.
Topics: Adenocarcinoma; Apoptosis; Cell Line, Tumor; Cell Proliferation; Chemical Fractionation; Chromatogra | 2006 |
Gallic acid causes inactivating phosphorylation of cdc25A/cdc25C-cdc2 via ATM-Chk2 activation, leading to cell cycle arrest, and induces apoptosis in human prostate carcinoma DU145 cells.
Topics: Apoptosis; Ataxia Telangiectasia Mutated Proteins; Caspases; CDC2 Protein Kinase; cdc25 Phosphatases | 2006 |
Cytotoxic effects of digalloyl dimer procyanidins in human cancer cell lines.
Topics: Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Catechin; Cell Line, Tumor; Cell Survival; Central | 2008 |
Chemopreventive effects of oral gallic acid feeding on tumor growth and progression in TRAMP mice.
Topics: Adenocarcinoma; Administration, Oral; Animals; Anticarcinogenic Agents; Cell Cycle; Disease Progress | 2008 |