gallic acid has been researched along with Parkinson Disease in 3 studies
gallate : A trihydroxybenzoate that is the conjugate base of gallic acid.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The neuropathology of Parkinson's disease (PD) is complex and affects multiple systems of the body beyond the central nervous system." | 1.91 | The effects of gallic acid and vagotomy on motor function, intestinal transit, brain electrophysiology and oxidative stress alterations in a rat model of Parkinson's disease induced by rotenone. ( Bavarsad, K; Farbood, Y; Mard, SA; Sarkaki, A; Sheikhpour, E, 2023) |
| "Gallic acid has been shown to both modulate factors leading to the onset of neurodegenerative disorders, as well as directly inhibit amyloid formation." | 1.56 | Gallic acid oxidation products alter the formation pathway of insulin amyloid fibrils. ( Sakalauskas, A; Smirnovas, V; Ziaunys, M, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Sheikhpour, E | 1 |
| Mard, SA | 1 |
| Farbood, Y | 2 |
| Bavarsad, K | 1 |
| Sarkaki, A | 2 |
| Sakalauskas, A | 1 |
| Ziaunys, M | 1 |
| Smirnovas, V | 1 |
| Mansouri, MT | 1 |
| Sameri, MJ | 1 |
| Naghizadeh, B | 1 |
| Rafeirad, M | 1 |
3 other studies available for gallic acid and Parkinson Disease
| Article | Year |
|---|---|
The effects of gallic acid and vagotomy on motor function, intestinal transit, brain electrophysiology and oxidative stress alterations in a rat model of Parkinson's disease induced by rotenone.
Topics: Animals; Brain; Disease Models, Animal; Electrophysiology; Gallic Acid; Male; Neuroprotective Agents | 2023 |
Gallic acid oxidation products alter the formation pathway of insulin amyloid fibrils.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Amyloidogenic Proteins; Gallic Acid; Humans; Insu | 2020 |
Neuroprotective effects of oral gallic acid against oxidative stress induced by 6-hydroxydopamine in rats.
Topics: Animals; Gallic Acid; Humans; Male; Memory; Neuroprotective Agents; Oxidative Stress; Oxidopamine; P | 2013 |