gallic acid has been researched along with Osteoarthritis in 10 studies
gallate : A trihydroxybenzoate that is the conjugate base of gallic acid.
Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Leonurine hydrochloride (LH) has been reported to exhibit a number of biological properties such as suppression of inflammation." | 7.96 | Leonurine Hydrochloride Suppresses Inflammatory Responses and Ameliorates Cartilage Degradation in Osteoarthritis via NF-κB Signaling Pathway. ( Chen, C; Hu, N; Huang, W; Liang, X; Zhu, Z, 2020) |
| "Leonurine hydrochloride (LH) has been reported to exhibit a number of biological properties such as suppression of inflammation." | 3.96 | Leonurine Hydrochloride Suppresses Inflammatory Responses and Ameliorates Cartilage Degradation in Osteoarthritis via NF-κB Signaling Pathway. ( Chen, C; Hu, N; Huang, W; Liang, X; Zhu, Z, 2020) |
| "Gallic acid (GA) and its derivatives are anti-inflammatory agents and are reported to have potent effects on Osteoarthritis (OA) treatment." | 3.83 | Synthesis, Biological Evaluation, and Docking Studies of a Novel Sulfonamido-Based Gallate as Pro-Chondrogenic Agent for the Treatment of Cartilage. ( Chai, L; Chen, H; Lin, C; Lin, X; Liu, B; Liu, Q; Zheng, L, 2016) |
| "Gallic acid (GA) and its derivatives are anti-inflammatory agents reported to have an effect on osteoarthritis (OA)." | 3.81 | A Novel Synthesized Sulfonamido-Based Gallate-JEZ-C as Potential Therapeutic Agents for Osteoarthritis. ( Lin, C; Lin, X; Liu, B; Lu, Z; Wei, S; Zhao, J; Zheng, L; Zou, Y, 2015) |
| "Leonurine treatment reduced both the mRNA and protein levels of Bax and increased the level of Bcl-2." | 1.51 | Leonurine Exerts Anti-Catabolic and Anti-Apoptotic Effects via Nuclear Factor kappa B (NF-κB) and Mitogen-Activated Protein Kinase (MAPK) Signaling Pathways in Chondrocytes. ( Hu, PF; Qian, J; Sun, FF, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (80.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abusharkh, HA | 1 |
| Reynolds, OM | 1 |
| Mendenhall, J | 1 |
| Gozen, BA | 1 |
| Tingstad, E | 1 |
| Idone, V | 1 |
| Abu-Lail, NI | 1 |
| Van Wie, BJ | 1 |
| Hu, PF | 1 |
| Sun, FF | 1 |
| Qian, J | 1 |
| Madzuki, IN | 1 |
| Lau, SF | 1 |
| Mohamad Shalan, NAA | 1 |
| Mohd Ishak, NI | 1 |
| Mohamed, S | 1 |
| Chen, C | 1 |
| Zhu, Z | 1 |
| Hu, N | 1 |
| Liang, X | 1 |
| Huang, W | 1 |
| Lu, Z | 3 |
| Liu, Q | 2 |
| Liu, L | 1 |
| Wu, H | 2 |
| Zheng, L | 4 |
| Zhao, JM | 1 |
| Yin, W | 1 |
| Lei, Y | 1 |
| Hu, ZC | 1 |
| Gong, LF | 1 |
| Li, XB | 1 |
| Fu, X | 1 |
| Xuan, JW | 1 |
| Feng, ZH | 1 |
| Ni, WF | 1 |
| Wei, S | 1 |
| Zou, Y | 1 |
| Lin, X | 3 |
| Lin, C | 3 |
| Liu, B | 3 |
| Zhao, J | 2 |
| Chai, L | 1 |
| Chen, H | 1 |
10 other studies available for gallic acid and Osteoarthritis
| Article | Year |
|---|---|
Combining stretching and gallic acid to decrease inflammation indices and promote extracellular matrix production in osteoarthritic human articular chondrocytes.
Topics: Cartilage, Articular; Cells, Cultured; Chondrocytes; Collagen Type I, alpha 1 Chain; Collagen Type I | 2021 |
Leonurine Exerts Anti-Catabolic and Anti-Apoptotic Effects via Nuclear Factor kappa B (NF-κB) and Mitogen-Activated Protein Kinase (MAPK) Signaling Pathways in Chondrocytes.
Topics: ADAM Proteins; Animals; Apoptosis; Cells, Cultured; Chondrocytes; Gallic Acid; Interleukin-1beta; Ma | 2019 |
Does cartilage ERα overexpression correlate with osteoarthritic chondrosenescence? Indications from
Topics: Aging; Animals; Bone Development; Cartilage; Chondrocytes; Diclofenac; Disease Models, Animal; Estro | 2019 |
Leonurine Hydrochloride Suppresses Inflammatory Responses and Ameliorates Cartilage Degradation in Osteoarthritis via NF-κB Signaling Pathway.
Topics: ADAMTS5 Protein; Animals; Anterior Cruciate Ligament; Anti-Inflammatory Agents; Cartilage Diseases; | 2020 |
A Novel Synthesized Sulfonamido-Based Gallate-JEZTC Blocks Cartilage Degradation on Rabbit Model of Osteoarthritis: An in Vitro and in Vivo Study.
Topics: Animals; Apoptosis; Benzamides; Cartilage, Articular; Chondrocytes; Disease Models, Animal; Down-Reg | 2018 |
Leonurine inhibits IL-1β induced inflammation in murine chondrocytes and ameliorates murine osteoarthritis.
Topics: Animals; Chondrocytes; Disease Models, Animal; Gallic Acid; Gene Expression Regulation; Interleukin- | 2018 |
Inhibition of PI3K/Akt/NF-κB signaling with leonurine for ameliorating the progression of osteoarthritis: In vitro and in vivo studies.
Topics: Animals; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Down-Regulation; Extracellular Matrix; Gal | 2019 |
A Novel Synthesized Sulfonamido-Based Gallate-JEZ-C as Potential Therapeutic Agents for Osteoarthritis.
Topics: Antioxidants; Cartilage, Articular; Cell Line; Chondrocytes; Gallic Acid; Humans; Inflammation; Oste | 2015 |
Chondro-Protective and Antiarthritic Effects of Sulfonamido-Based Gallate-ZXHA-TC in Vitro and in Vivo.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cartilage, Articular; Cell Proliferation; Chondroc | 2016 |
Synthesis, Biological Evaluation, and Docking Studies of a Novel Sulfonamido-Based Gallate as Pro-Chondrogenic Agent for the Treatment of Cartilage.
Topics: ADAMTS5 Protein; Aggrecans; Animals; Anti-Inflammatory Agents; Cartilage, Articular; Cell Proliferat | 2016 |