gallic acid has been researched along with Necrosis in 19 studies
gallate : A trihydroxybenzoate that is the conjugate base of gallic acid.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study was intended to appraise the nutraceutical inherent of HPLC standardized Spinacia oleracea methanolic leaf extract (SoLE) in isoproterenol (ISO) induced male albino Wistar rats via activation of pro-inflammatory signaling pathway that drives myocardial necrosis." | 7.85 | Nutraceutical inherent of Spinacia oleracea Linn. methanolic leaf extract ameliorates isoproterenol induced myocardial necrosis in male albino Wistar rats via mitigating inflammation. ( Jolapuram, U; Kodidhela, LD; Vutharadhi, S, 2017) |
| "These results provide evidence for the first time that GA causes selective HSC death through a Ca(2+)/calpain I-mediated necrosis cascade, suggesting that GA may represent a potential therapeutic agent to combat liver fibrosis." | 7.80 | Gallic acid selectively induces the necrosis of activated hepatic stellate cells via a calcium-dependent calpain I activation pathway. ( Hsieh, SC; Hsu, SL; Hsueh, CM; Liu, MC; Wu, CC; Wu, CH; Yen, JH, 2014) |
| " The present study was intended to appraise the nutraceutical inherent of HPLC standardized Spinacia oleracea methanolic leaf extract (SoLE) in isoproterenol (ISO) induced male albino Wistar rats via activation of pro-inflammatory signaling pathway that drives myocardial necrosis." | 3.85 | Nutraceutical inherent of Spinacia oleracea Linn. methanolic leaf extract ameliorates isoproterenol induced myocardial necrosis in male albino Wistar rats via mitigating inflammation. ( Jolapuram, U; Kodidhela, LD; Vutharadhi, S, 2017) |
| "These results provide evidence for the first time that GA causes selective HSC death through a Ca(2+)/calpain I-mediated necrosis cascade, suggesting that GA may represent a potential therapeutic agent to combat liver fibrosis." | 3.80 | Gallic acid selectively induces the necrosis of activated hepatic stellate cells via a calcium-dependent calpain I activation pathway. ( Hsieh, SC; Hsu, SL; Hsueh, CM; Liu, MC; Wu, CC; Wu, CH; Yen, JH, 2014) |
| "In this study, we investigated the hepatoprotective effects of four compounds from Galla Rhois [gallic acid methyl ester, gallic acid, an equilibrium mixture of 3-galloyl-gallic acid and 4-galloyl-gallic acid isomers, and 1,2,3,4,6-penta- O-galloyl- beta- D-glucose (PGG)] in primary rat hepatocytes undergoing necrosis or apoptosis." | 3.74 | 1,2,3,4,6-penta-O-galloyl-beta-D-glucose from Galla Rhois protects primary rat hepatocytes from necrosis and apoptosis. ( An, RB; Kim, YC; Park, EJ; Sohn, DH; Zhao, YZ, 2008) |
| "Acetaminophen is a commonly used drug for the treatment of patients with common cold and influenza." | 1.35 | Phyllanthus urinaria extract attenuates acetaminophen induced hepatotoxicity: involvement of cytochrome P450 CYP2E1. ( Chan, AK; Chan, AS; Cheng, CH; Cheng, GY; Chui, CH; Fong, DW; Gambari, R; Hau, DK; Kan, CW; Kok, SH; Lai, PB; Lau, FY; Leung, AK; Tang, JC; Tong, CS; Wong, RS; Wong, WY; Yuen, MC; Zhu, GY, 2009) |
| "Pre-treatment with gallic acid significantly rendered K562 cells more susceptible to NK cell-mediated necrosis, while pre-treatment with rutin significantly rendered K562 cells more susceptible to apoptosis." | 1.33 | Effect of phenols on natural killer (NK) cell-mediated death in the K562 human leukemic cell line. ( Andrikopoulos, NK; Dedoussis, GV; Kaliora, AC, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (10.53) | 18.2507 |
| 2000's | 6 (31.58) | 29.6817 |
| 2010's | 10 (52.63) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Gomes, INF | 1 |
| Silva, AG | 1 |
| Frazao Lima, GF | 1 |
| Longatti, TR | 1 |
| Do Carmo, LF | 1 |
| Villar, JAFP | 1 |
| Araujo, AADC | 1 |
| Tome, RG | 1 |
| Santos, HBD | 1 |
| Azambuja Ribeiro, RIM | 1 |
| Zhou, Y | 1 |
| Jin, H | 1 |
| Wu, Y | 1 |
| Chen, L | 1 |
| Bao, X | 1 |
| Lu, C | 1 |
| Hsieh, SC | 2 |
| Wu, CH | 1 |
| Wu, CC | 2 |
| Yen, JH | 2 |
| Liu, MC | 1 |
| Hsueh, CM | 1 |
| Hsu, SL | 3 |
| Sun, DP | 1 |
| Li, XX | 1 |
| Liu, XL | 1 |
| Zhao, D | 1 |
| Qiu, FQ | 1 |
| Li, Y | 1 |
| Ma, P | 1 |
| Tam, J | 1 |
| Beilhartz, GL | 1 |
| Auger, A | 1 |
| Gupta, P | 1 |
| Therien, AG | 1 |
| Melnyk, RA | 1 |
| Chang, YJ | 1 |
| Liu, YT | 1 |
| Lin, YH | 1 |
| Lin, MH | 1 |
| Huang, SJ | 1 |
| Ho, JA | 1 |
| Wu, LC | 1 |
| Sachdeva, M | 1 |
| Chadha, R | 1 |
| Kumar, A | 1 |
| Karan, M | 1 |
| Singh, T | 1 |
| Dhingra, S | 1 |
| Vutharadhi, S | 1 |
| Jolapuram, U | 1 |
| Kodidhela, LD | 1 |
| Park, EJ | 1 |
| Zhao, YZ | 1 |
| An, RB | 1 |
| Kim, YC | 1 |
| Sohn, DH | 1 |
| Hau, DK | 1 |
| Gambari, R | 1 |
| Wong, RS | 1 |
| Yuen, MC | 1 |
| Cheng, GY | 1 |
| Tong, CS | 1 |
| Zhu, GY | 1 |
| Leung, AK | 1 |
| Lai, PB | 1 |
| Lau, FY | 1 |
| Chan, AK | 1 |
| Wong, WY | 1 |
| Kok, SH | 1 |
| Cheng, CH | 1 |
| Kan, CW | 1 |
| Chan, AS | 1 |
| Chui, CH | 1 |
| Tang, JC | 1 |
| Fong, DW | 1 |
| You, BR | 1 |
| Moon, HJ | 1 |
| Han, YH | 1 |
| Park, WH | 1 |
| Mahadeswaraswamy, YH | 1 |
| Kumar, MS | 1 |
| Gowtham, YJ | 1 |
| Nagaraju, S | 1 |
| Girish, KS | 1 |
| Kemparaju, K | 1 |
| Dedoussis, GV | 1 |
| Kaliora, AC | 1 |
| Andrikopoulos, NK | 1 |
| Łabieniec, M | 1 |
| Gabryelak, T | 2 |
| Labieniec, M | 1 |
| Chiou, GC | 1 |
| Hong, SJ | 2 |
| Zhu, J | 1 |
| Filippich, LJ | 1 |
| Ng, J | 1 |
| Hwang, JH | 1 |
19 other studies available for gallic acid and Necrosis
| Article | Year |
|---|---|
Alkaloid and phenolic compounds of Xylopia aromatica inhibits tumor growth by down-regulating matrix metalloproteinase-2 (MMP-2) expression.
Topics: Alkaloids; Animals; Aporphines; Carcinoma, Ehrlich Tumor; Catechin; Cell Line, Tumor; Cell Prolifera | 2021 |
Gallic acid protects against ethanol-induced hepatocyte necroptosis via an NRF2-dependent mechanism.
Topics: Apoptosis; Cell Line; Ethanol; Gallic Acid; Hepatocytes; Humans; Necrosis; NF-E2-Related Factor 2; N | 2019 |
Gallic acid selectively induces the necrosis of activated hepatic stellate cells via a calcium-dependent calpain I activation pathway.
Topics: Animals; Antioxidants; Calcium; Calpain; Dose-Response Relationship, Drug; Gallic Acid; Hepatic Stel | 2014 |
Gypenosides induce apoptosis by ca2+ overload mediated by endoplasmic-reticulum and store-operated ca2+ channels in human hepatoma cells.
Topics: Antineoplastic Agents; Apoptosis; Boron Compounds; Calcium; Calcium Channel Blockers; Calcium Channe | 2013 |
Small molecule inhibitors of Clostridium difficile toxin B-induced cellular damage.
Topics: Animals; Bacterial Proteins; Bacterial Toxins; Biflavonoids; Catechin; Cell Line; Cell Survival; Chl | 2015 |
Gallic acid induces necroptosis via TNF-α signaling pathway in activated hepatic stellate cells.
Topics: Animals; Apoptosis; Blotting, Western; Caspases; Cell Cycle; Cell Proliferation; Cells, Cultured; Ch | 2015 |
Hepatoprotective effect of trimethylgallic acid esters against carbon tetrachloride-induced liver injury in rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Carbon Tetrachloride; Chemical and Drug | 2015 |
Molecular mechanisms of gallic acid-induced growth inhibition, apoptosis, and necrosis in hypertrophic scar fibroblasts.
Topics: Apoptosis; Calcium; Calpain; Cell Cycle; Cells, Cultured; Cicatrix, Hypertrophic; Dose-Response Rela | 2017 |
Nutraceutical inherent of Spinacia oleracea Linn. methanolic leaf extract ameliorates isoproterenol induced myocardial necrosis in male albino Wistar rats via mitigating inflammation.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Cardiomyopathies; Chromatography, High Pressure Liquid | 2017 |
1,2,3,4,6-penta-O-galloyl-beta-D-glucose from Galla Rhois protects primary rat hepatocytes from necrosis and apoptosis.
Topics: Animals; Aphids; Apoptosis; Cells, Cultured; Gallic Acid; Hepatocytes; Hydrolyzable Tannins; Necrosi | 2008 |
Phyllanthus urinaria extract attenuates acetaminophen induced hepatotoxicity: involvement of cytochrome P450 CYP2E1.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1 Inhibitors; | 2009 |
Gallic acid inhibits the growth of HeLa cervical cancer cells via apoptosis and/or necrosis.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Cell Survival; Drug Screening Assays, Antitumor; E | 2010 |
The polyphenol 3, 4, 5 - tri-hydroxy benzoic acid inhibits indian daboia russelli venom and its hemorrhagic complex induced local toxicity.
Topics: Animals; Antivenins; Circular Dichroism; Daboia; Edema; Erythrocytes; Extracellular Matrix Proteins; | 2011 |
Effect of phenols on natural killer (NK) cell-mediated death in the K562 human leukemic cell line.
Topics: Annexin A5; Annexins; Apoptosis; Cell Death; Cell Line, Tumor; Cell Separation; Coculture Techniques | 2005 |
Oxidatively modified proteins and DNA in digestive gland cells of the fresh-water mussel Unio tumidus in the presence of tannic acid and its derivatives.
Topics: Animals; Apoptosis; Bivalvia; Comet Assay; Cross-Linking Reagents; DNA Damage; Dose-Response Relatio | 2006 |
Study of interactions between phenolic compounds and H2O2 or Cu(II) ions in B14 Chinese hamster cells.
Topics: Animals; Antioxidants; Apoptosis; Cell Line; Cell Survival; Copper; Cricetinae; Cricetulus; Dose-Res | 2006 |
Prevention and reduction of neural damage in ischemic strokes by w-(N,N'-diethylamino)-n-alkyl-3,4,5-trimethoxybenzoate compounds.
Topics: Animals; Aorta; Brain Ischemia; Calcium; Calcium Channel Blockers; Cells, Cultured; Cerebral Cortex; | 1995 |
Rumen involvement in sheep tannic acid metabolism.
Topics: Abomasum; Administration, Oral; Animals; Chromatography, High Pressure Liquid; Ellagic Acid; Gallic | 1995 |
Reduction of neuronal damage in ischemic stroke using a combination therapy of TMB-8 with L-arginine.
Topics: Animals; Arginine; Brain Ischemia; Calcium; Calcium Channel Blockers; Drug Therapy, Combination; Gal | 2000 |