gallic acid has been researched along with Leukemia in 7 studies
gallate : A trihydroxybenzoate that is the conjugate base of gallic acid.
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of the present study was to explore the signaling pathways associated with gallic acid induced matrix metalloproteinase-2 (MMP-2)/MMP-9 downregulation in human leukemia K562 cells." | 7.78 | Gallic acid downregulates matrix metalloproteinase-2 (MMP-2) and MMP-9 in human leukemia cells with expressed Bcr/Abl. ( Chang, LS; Chen, YJ, 2012) |
| "Gallic acid and gallates with the same number of hydroxyl groups and varying the length of the side carbon chain, with respective lipophilicity being defined through the ClogP values, were examined for their ability to induce apoptosis (through the DNA ladder fragmentation pattern), mitochondrial and cytoplasmic GSH depletion and NF-kappaB activation in murine lymphoblastic L1210 leukemia cells." | 7.74 | Ester derivatives of gallic acid with potential toxicity toward L1210 leukemia cells. ( Bazzo, ML; Creczynski-Pasa, TB; de Souza, CA; Leal, P; Licínio, MA; Locatelli, C; Rosso, R; Santos-Silva, MC; Yunes, RA, 2008) |
| "Leukemia is a common malignancy affecting humans worldwide." | 5.62 | Gallic acid enhances pirarubicin‑induced anticancer in living K562 and K562/Dox leukemia cancer cells through cellular energetic state impairment and P‑glycoprotein inhibition. ( Aye, KT; Kothan, S; Pan, J; Supawat, B; Tima, S; Tungjai, M; Udomtanakunchai, C; Wattanapongpitak, S, 2021) |
| "The aim of the present study was to explore the signaling pathways associated with gallic acid induced matrix metalloproteinase-2 (MMP-2)/MMP-9 downregulation in human leukemia K562 cells." | 3.78 | Gallic acid downregulates matrix metalloproteinase-2 (MMP-2) and MMP-9 in human leukemia cells with expressed Bcr/Abl. ( Chang, LS; Chen, YJ, 2012) |
| "Gallic acid and gallates with the same number of hydroxyl groups and varying the length of the side carbon chain, with respective lipophilicity being defined through the ClogP values, were examined for their ability to induce apoptosis (through the DNA ladder fragmentation pattern), mitochondrial and cytoplasmic GSH depletion and NF-kappaB activation in murine lymphoblastic L1210 leukemia cells." | 3.74 | Ester derivatives of gallic acid with potential toxicity toward L1210 leukemia cells. ( Bazzo, ML; Creczynski-Pasa, TB; de Souza, CA; Leal, P; Licínio, MA; Locatelli, C; Rosso, R; Santos-Silva, MC; Yunes, RA, 2008) |
| "Leukemia is a common malignancy affecting humans worldwide." | 1.62 | Gallic acid enhances pirarubicin‑induced anticancer in living K562 and K562/Dox leukemia cancer cells through cellular energetic state impairment and P‑glycoprotein inhibition. ( Aye, KT; Kothan, S; Pan, J; Supawat, B; Tima, S; Tungjai, M; Udomtanakunchai, C; Wattanapongpitak, S, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Locatelli, C | 1 |
| Rosso, R | 1 |
| Santos-Silva, MC | 1 |
| de Souza, CA | 1 |
| Licínio, MA | 1 |
| Leal, P | 1 |
| Bazzo, ML | 1 |
| Yunes, RA | 1 |
| Creczynski-Pasa, TB | 1 |
| Kakumu, A | 1 |
| Ninomiya, M | 1 |
| Efdi, M | 1 |
| Adfa, M | 1 |
| Hayashi, M | 1 |
| Tanaka, K | 1 |
| Koketsu, M | 1 |
| Aye, KT | 1 |
| Wattanapongpitak, S | 1 |
| Supawat, B | 1 |
| Kothan, S | 1 |
| Udomtanakunchai, C | 1 |
| Tima, S | 1 |
| Pan, J | 1 |
| Tungjai, M | 1 |
| Zhuang, Q | 1 |
| Ruan, L | 1 |
| Jin, T | 1 |
| Zheng, X | 1 |
| Jin, Z | 1 |
| Soltani, A | 1 |
| Shams Abadi, MS | 1 |
| Raeisi, M | 1 |
| Kouhihabibidehkordi, G | 1 |
| Eshaghi, F | 1 |
| Mohreh, O | 1 |
| Rafieian-Kopaei, M | 1 |
| Saiko, P | 1 |
| Graser, G | 1 |
| Madlener, S | 1 |
| Schwarz, S | 1 |
| Krupitza, G | 1 |
| Jaeger, W | 1 |
| Somepalli, V | 1 |
| Golakoti, T | 1 |
| Fritzer-Szekeres, M | 1 |
| Szekeres, T | 1 |
| Chen, YJ | 1 |
| Chang, LS | 1 |
1 review available for gallic acid and Leukemia
| Article | Year |
|---|---|
Apoptosis-inducing Plant-based Phenolic Compounds are Effective on Leukemia Cell Lines.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Cell Line; Gallic Acid; Humans; Leukemia | 2023 |
6 other studies available for gallic acid and Leukemia
| Article | Year |
|---|---|
Ester derivatives of gallic acid with potential toxicity toward L1210 leukemia cells.
Topics: Animals; Cell Survival; Esters; Gallic Acid; Hydrophobic and Hydrophilic Interactions; Leukemia; Leu | 2008 |
Phytochemical analysis and antileukemic activity of polyphenolic constituents of Toona sinensis.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; Cell Survival; Dose-Response Relat | 2014 |
Gallic acid enhances pirarubicin‑induced anticancer in living K562 and K562/Dox leukemia cancer cells through cellular energetic state impairment and P‑glycoprotein inhibition.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Survival; Doxor | 2021 |
Anti-leukaemia effects of leonurine in vitro and in vivo.
Topics: Animals; Gallic Acid; HL-60 Cells; Humans; Leukemia; Mice; Mice, Nude; Phosphatidylinositol 3-Kinase | 2021 |
Combination effects of digalloylresveratrol with arabinofuranosylcytosine and difluorodeoxycytidine in human leukemia and pancreatic cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Proliferation; Cytarabine; Deoxycytidine; Galli | 2011 |
Gallic acid downregulates matrix metalloproteinase-2 (MMP-2) and MMP-9 in human leukemia cells with expressed Bcr/Abl.
Topics: Activating Transcription Factor 2; beta-Transducin Repeat-Containing Proteins; Down-Regulation; Fusi | 2012 |