Page last updated: 2024-10-17

gallic acid and Insulin Sensitivity

gallic acid has been researched along with Insulin Sensitivity in 10 studies

gallate : A trihydroxybenzoate that is the conjugate base of gallic acid.

Research Excerpts

ExcerptRelevanceReference
" Of interest is gallic acid, a trihydroxybenzoic acid that has progressively demonstrated robust anti-obesity capabilities in various experimental models."8.98Inflammation and Oxidative Stress in an Obese State and the Protective Effects of Gallic Acid. ( Dludla, PV; Jack, B; Louw, J; Mazibuko-Mbeje, SE; Mkandla, Z; Mutize, T; Nkambule, BB; Orlando, P; Silvestri, S; Tiano, L, 2018)
" officinalis fruit juice and gallic acid facilitated their glucose homeostasis; improved insulin sensitivity; reduced obesity; abridged elevated blood pressure and declined cholesterol level, and also induced adipogenesis in 3T3-L1 adipocytes."7.96Antidiabetic potential of gallic acid from Emblica officinalis: Improved glucose transporters and insulin sensitivity through PPAR-γ and Akt signaling. ( Bakrania, AK; Patel, SS; Variya, BC, 2020)
"Gallic acid (GA) is a plant-derived triphenolic chemical with multiple cardio-protective properties, such as antiobesity, anti-inflammation, and antioxidation."5.72Low-Dose Gallic Acid Administration Does Not Improve Diet-Induced Metabolic Disorders and Atherosclerosis in Apoe Knockout Mice. ( An, X; Bai, J; Liao, J; Lin, QY; Liu, S; Wang, Y; Xie, Y, 2022)
" Of interest is gallic acid, a trihydroxybenzoic acid that has progressively demonstrated robust anti-obesity capabilities in various experimental models."4.98Inflammation and Oxidative Stress in an Obese State and the Protective Effects of Gallic Acid. ( Dludla, PV; Jack, B; Louw, J; Mazibuko-Mbeje, SE; Mkandla, Z; Mutize, T; Nkambule, BB; Orlando, P; Silvestri, S; Tiano, L, 2018)
" This study aimed at investigating the effect of hamamelitannin on glycogen synthesis in an insulin resistance model using L6 myotubes."3.96Molecular process of glucose uptake and glycogen storage due to hamamelitannin via insulin signalling cascade in glucose metabolism. ( Al-Dhabi, NA; Arasu, MV; Arockiaraj, J; Arshad, A; Chandrakumar, SS; Guru, A; Issac, PK; Lite, C; Saraswathi, NT, 2020)
" officinalis fruit juice and gallic acid facilitated their glucose homeostasis; improved insulin sensitivity; reduced obesity; abridged elevated blood pressure and declined cholesterol level, and also induced adipogenesis in 3T3-L1 adipocytes."3.96Antidiabetic potential of gallic acid from Emblica officinalis: Improved glucose transporters and insulin sensitivity through PPAR-γ and Akt signaling. ( Bakrania, AK; Patel, SS; Variya, BC, 2020)
"This study investigated the influence of caffeic, ferulic, gallic and protocatechuic acids on high-fructose diet-induced metabolic syndrome in rats."3.88Dietary phenolic acids reverse insulin resistance, hyperglycaemia, dyslipidaemia, inflammation and oxidative stress in high-fructose diet-induced metabolic syndrome rats. ( Ajiboye, TO; Ibitoye, OB, 2018)
"Gallic acid (GA), a naturally abundant plant phenolic compound in vegetables and fruits, has been shown to have potent anti-oxidative and anti-obesity activity."3.80Gallic acid ameliorated impaired glucose and lipid homeostasis in high fat diet-induced NAFLD mice. ( Chao, J; Cheng, HY; Hsieh, MT; Huo, TI; Lee, MS; Liao, JW; Pao, LH; Peng, WH; Qin, XM; Tsai, JC, 2014)
"Gallic acid (GA) is a plant-derived triphenolic chemical with multiple cardio-protective properties, such as antiobesity, anti-inflammation, and antioxidation."1.72Low-Dose Gallic Acid Administration Does Not Improve Diet-Induced Metabolic Disorders and Atherosclerosis in Apoe Knockout Mice. ( An, X; Bai, J; Liao, J; Lin, QY; Liu, S; Wang, Y; Xie, Y, 2022)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (60.00)24.3611
2020's4 (40.00)2.80

Authors

AuthorsStudies
Xu, Y1
Tang, G1
Zhang, C1
Wang, N1
Feng, Y1
Bai, J1
Lin, QY1
An, X1
Liu, S1
Wang, Y1
Xie, Y1
Liao, J1
Issac, PK1
Guru, A1
Chandrakumar, SS1
Lite, C1
Saraswathi, NT1
Arasu, MV1
Al-Dhabi, NA2
Arshad, A1
Arockiaraj, J1
Ibitoye, OB1
Ajiboye, TO1
Costabile, G1
Vitale, M1
Luongo, D1
Naviglio, D1
Vetrani, C1
Ciciola, P1
Tura, A1
Castello, F1
Mena, P1
Del Rio, D1
Capaldo, B1
Rivellese, AA1
Riccardi, G1
Giacco, R1
Dludla, PV1
Nkambule, BB1
Jack, B1
Mkandla, Z1
Mutize, T1
Silvestri, S1
Orlando, P1
Tiano, L1
Louw, J1
Mazibuko-Mbeje, SE1
Variya, BC1
Bakrania, AK1
Patel, SS1
Chao, J1
Huo, TI1
Cheng, HY1
Tsai, JC1
Liao, JW1
Lee, MS1
Qin, XM1
Hsieh, MT1
Pao, LH1
Peng, WH1
Gandhi, GR1
Jothi, G1
Antony, PJ1
Balakrishna, K1
Paulraj, MG1
Ignacimuthu, S1
Stalin, A1
Huang, DW1
Chang, WC1
Wu, JS1
Shih, RW1
Shen, SC1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of the Bioavailability of Polyphenols From a Red Grape Extract-based Drink and the Acute Effects of Its Consumption on Glucose and Lipid Response During the Subsequent Meal[NCT02865278]10 participants (Actual)Interventional2016-03-31Active, not recruiting
Effect of Spirulina Platensis Supplementation and Calorie Restriction on Anthropometric, Body Composition, Lipid Profiles, Insulin Resistance, Stress Oxidative Biomarkers In Obese Men: A Randomized Controlled Trial Protocol Study[NCT06076161]32 participants (Actual)Interventional2023-10-17Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for gallic acid and Insulin Sensitivity

ArticleYear
Gallic Acid and Diabetes Mellitus: Its Association with Oxidative Stress.
    Molecules (Basel, Switzerland), 2021, Nov-24, Volume: 26, Issue:23

    Topics: Antioxidants; Diabetes Mellitus, Type 2; Gallic Acid; Humans; Hyperglycemia; Hypoglycemic Agents; In

2021
Inflammation and Oxidative Stress in an Obese State and the Protective Effects of Gallic Acid.
    Nutrients, 2018, Dec-21, Volume: 11, Issue:1

    Topics: Adipokines; Adipose Tissue; Animals; Cytokines; Diet; Fruit; Gallic Acid; Humans; Inflammation; Insu

2018

Trials

1 trial available for gallic acid and Insulin Sensitivity

ArticleYear
Grape pomace polyphenols improve insulin response to a standard meal in healthy individuals: A pilot study.
    Clinical nutrition (Edinburgh, Scotland), 2019, Volume: 38, Issue:6

    Topics: Adult; Blood Glucose; Cross-Over Studies; Fruit and Vegetable Juices; Gallic Acid; Humans; Insulin;

2019

Other Studies

7 other studies available for gallic acid and Insulin Sensitivity

ArticleYear
Low-Dose Gallic Acid Administration Does Not Improve Diet-Induced Metabolic Disorders and Atherosclerosis in Apoe Knockout Mice.
    Journal of immunology research, 2022, Volume: 2022

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Cardiovascular Diseases; Diet, High-Fat; Gallic Acid; I

2022
Molecular process of glucose uptake and glycogen storage due to hamamelitannin via insulin signalling cascade in glucose metabolism.
    Molecular biology reports, 2020, Volume: 47, Issue:9

    Topics: Animals; Biological Transport; Carbohydrate Metabolism; Cell Survival; Diabetes Mellitus, Type 2; Ga

2020
Dietary phenolic acids reverse insulin resistance, hyperglycaemia, dyslipidaemia, inflammation and oxidative stress in high-fructose diet-induced metabolic syndrome rats.
    Archives of physiology and biochemistry, 2018, Volume: 124, Issue:5

    Topics: Animals; Anti-Obesity Agents; Antioxidants; Biomarkers; Caffeic Acids; Coumaric Acids; Cytokines; Di

2018
Antidiabetic potential of gallic acid from Emblica officinalis: Improved glucose transporters and insulin sensitivity through PPAR-γ and Akt signaling.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2020, Jul-15, Volume: 73

    Topics: 3T3-L1 Cells; Adipogenesis; Animals; Diabetes Mellitus, Experimental; Fruit and Vegetable Juices; Ga

2020
Gallic acid ameliorated impaired glucose and lipid homeostasis in high fat diet-induced NAFLD mice.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Animals; Diet, High-Fat; Gallic Acid; Glucose; Homeostasis; Hypercholesterolemia; Insulin Resistance

2014
Gallic acid attenuates high-fat diet fed-streptozotocin-induced insulin resistance via partial agonism of PPARγ in experimental type 2 diabetic rats and enhances glucose uptake through translocation and activation of GLUT4 in PI3K/p-Akt signaling pathway.
    European journal of pharmacology, 2014, Dec-15, Volume: 745

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Gallic Acid; Ge

2014
Gallic acid ameliorates hyperglycemia and improves hepatic carbohydrate metabolism in rats fed a high-fructose diet.
    Nutrition research (New York, N.Y.), 2016, Volume: 36, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; C-Peptide; Carbohydrate Metabolism;

2016