Page last updated: 2024-10-17

gallic acid and Glioma

gallic acid has been researched along with Glioma in 9 studies

gallate : A trihydroxybenzoate that is the conjugate base of gallic acid.

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
"In our study, the effects of gallic acid (GA), a natural therapeutic agent, on oxidative stress biomarkers and MMP-2 and MMP-9 expressions via the p38/JNK pathway in C6 glioma cells were investigated."8.31Effects of gallic acid on expressions of MMP-2 and MMP-9 through the pathway of p38/JNK in C6 glioma cells. ( Bellioglu Yaka, E; Coskun Yazici, ZM; Ersoz, M; Gulsoy, N, 2023)
" Thus, methyl gallate is a potent anti-tumor and novel therapeutic agent for glioma."7.79Antitumor activity of methyl gallate by inhibition of focal adhesion formation and Akt phosphorylation in glioma cells. ( Choi, SY; Eum, WS; Han, KH; Hwang, HS; Kim, DW; Kim, JK; Lee, SH; Oh, JS; Park, J, 2013)
"Phospholipid metabolism was studied in N1E-115 neuroblastoma and C6 glioma cells exposed to thapsigargin, a selective inhibitor of endoplasmic reticulum Ca(2+)-ATPase that raises the cytosolic free Ca2+ concentration [Ca2+]i."7.69Thapsigargin selectively stimulates synthesis of phosphatidylglycerol in N1E-115 neuroblastoma cells and phosphatidylinositol in C6 glioma cells. ( Byers, DM; Cook, HW; Palmer, FB, 1994)
"Glioblastoma (GBM) is the deadliest primary brain tumor in adults due to the high rate of relapse with current treatment."5.72Impact of gallic acid on tumor suppression: Modulation of redox homeostasis and purinergic response in in vitro and a preclinical glioblastoma model. ( Alves, FL; Bona, NP; Braganhol, E; de Aguiar, MSS; Pedra, NS; Santos, FDSD; Saraiva, JT; Spanevello, RM; Spohr, L; Stefanello, FM, 2022)
"Gallic acid is a well-established antioxidant, presenting a promising new selective anti-cancer drug, while gold nanoparticles (GNPs) can be developed as versatile nontoxic carriers for anti-cancer drug delivery."5.62Gallic acid-gold nanoparticles enhance radiation-induced cell death of human glioma U251 cells. ( Fu, X; Hu, W; Jing, Z; Li, M; Liang, W; Ma, J; Meng, E; Wang, H; Wang, X; Yang, Z; Zhang, H; Zhou, S, 2021)
"In our study, the effects of gallic acid (GA), a natural therapeutic agent, on oxidative stress biomarkers and MMP-2 and MMP-9 expressions via the p38/JNK pathway in C6 glioma cells were investigated."4.31Effects of gallic acid on expressions of MMP-2 and MMP-9 through the pathway of p38/JNK in C6 glioma cells. ( Bellioglu Yaka, E; Coskun Yazici, ZM; Ersoz, M; Gulsoy, N, 2023)
" Thus, methyl gallate is a potent anti-tumor and novel therapeutic agent for glioma."3.79Antitumor activity of methyl gallate by inhibition of focal adhesion formation and Akt phosphorylation in glioma cells. ( Choi, SY; Eum, WS; Han, KH; Hwang, HS; Kim, DW; Kim, JK; Lee, SH; Oh, JS; Park, J, 2013)
"Phospholipid metabolism was studied in N1E-115 neuroblastoma and C6 glioma cells exposed to thapsigargin, a selective inhibitor of endoplasmic reticulum Ca(2+)-ATPase that raises the cytosolic free Ca2+ concentration [Ca2+]i."3.69Thapsigargin selectively stimulates synthesis of phosphatidylglycerol in N1E-115 neuroblastoma cells and phosphatidylinositol in C6 glioma cells. ( Byers, DM; Cook, HW; Palmer, FB, 1994)
"Glioblastoma (GBM) is the deadliest primary brain tumor in adults due to the high rate of relapse with current treatment."1.72Impact of gallic acid on tumor suppression: Modulation of redox homeostasis and purinergic response in in vitro and a preclinical glioblastoma model. ( Alves, FL; Bona, NP; Braganhol, E; de Aguiar, MSS; Pedra, NS; Santos, FDSD; Saraiva, JT; Spanevello, RM; Spohr, L; Stefanello, FM, 2022)
"Gallic acid is a well-established antioxidant, presenting a promising new selective anti-cancer drug, while gold nanoparticles (GNPs) can be developed as versatile nontoxic carriers for anti-cancer drug delivery."1.62Gallic acid-gold nanoparticles enhance radiation-induced cell death of human glioma U251 cells. ( Fu, X; Hu, W; Jing, Z; Li, M; Liang, W; Ma, J; Meng, E; Wang, H; Wang, X; Yang, Z; Zhang, H; Zhou, S, 2021)
" To assay the effects of chronic administration of the MO extract on PH, control, MCT and MCT+MO groups were designated."1.38Effects of 2-azafluorenones on phosphatidyl-inositol specific phospholipase C activation in c6 glioma cells. ( Wang, HL; Wei, JW, 2012)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (22.22)18.2507
2000's0 (0.00)29.6817
2010's4 (44.44)24.3611
2020's3 (33.33)2.80

Authors

AuthorsStudies
Pedra, NS1
Bona, NP1
de Aguiar, MSS1
Spohr, L1
Alves, FL1
Santos, FDSD1
Saraiva, JT1
Stefanello, FM1
Braganhol, E2
Spanevello, RM1
Bellioglu Yaka, E1
Coskun Yazici, ZM1
Ersoz, M1
Gulsoy, N1
Jing, Z1
Li, M1
Wang, H1
Yang, Z1
Zhou, S1
Ma, J1
Meng, E1
Zhang, H1
Liang, W1
Hu, W1
Wang, X1
Fu, X1
Dos Santos, DM1
Rocha, CVJ1
da Silveira, EF1
Marinho, MAG1
Rodrigues, MR1
Silva, NO1
da Silva Ferreira, A1
de Moura, NF1
Darelli, GJS1
Horn, AP1
de Lima, VR1
Lee, SH1
Kim, JK1
Kim, DW1
Hwang, HS1
Eum, WS1
Park, J1
Han, KH1
Oh, JS1
Choi, SY1
Lu, Y1
Jiang, F1
Jiang, H1
Wu, K1
Zheng, X1
Cai, Y1
Katakowski, M1
Chopp, M1
To, SS1
Wang, HL1
Wei, JW1
Palmer, FB1
Cook, HW1
Byers, DM1
Yamasaki, T1
Enomoto, K1
Moritake, K1
Maeno, T1

Other Studies

9 other studies available for gallic acid and Glioma

ArticleYear
Impact of gallic acid on tumor suppression: Modulation of redox homeostasis and purinergic response in in vitro and a preclinical glioblastoma model.
    The Journal of nutritional biochemistry, 2022, Volume: 110

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Gallic Acid; Glioblastoma; Glioma; Homeostasis; Nucleoti

2022
Effects of gallic acid on expressions of MMP-2 and MMP-9 through the pathway of p38/JNK in C6 glioma cells.
    Pakistan journal of pharmaceutical sciences, 2023, Volume: 36, Issue:1

    Topics: Cell Line, Tumor; Gallic Acid; Glioma; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase

2023
Gallic acid-gold nanoparticles enhance radiation-induced cell death of human glioma U251 cells.
    IUBMB life, 2021, Volume: 73, Issue:2

    Topics: Apoptosis; Brain Neoplasms; Cell Cycle; Cell Death; Drug Delivery Systems; Gallic Acid; Gamma Rays;

2021
In Vitro Anti/Pro-oxidant Activities of R. ferruginea Extract and Its Effect on Glioma Cell Viability: Correlation with Phenolic Compound Content and Effects on Membrane Dynamics.
    The Journal of membrane biology, 2018, Volume: 251, Issue:2

    Topics: Antioxidants; Catechin; Cell Line, Tumor; Cell Survival; Gallic Acid; Glioma; Humans; Liposomes; Myr

2018
Antitumor activity of methyl gallate by inhibition of focal adhesion formation and Akt phosphorylation in glioma cells.
    Biochimica et biophysica acta, 2013, Volume: 1830, Issue:8

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Calcium; Cell Line, Tumor; Cell Movement; Cell Surv

2013
Gallic acid suppresses cell viability, proliferation, invasion and angiogenesis in human glioma cells.
    European journal of pharmacology, 2010, Sep-01, Volume: 641, Issue:2-3

    Topics: Animals; Blotting, Western; Brain Neoplasms; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell S

2010
Effects of 2-azafluorenones on phosphatidyl-inositol specific phospholipase C activation in c6 glioma cells.
    The Chinese journal of physiology, 2012, Apr-30, Volume: 55, Issue:2

    Topics: Aluminum Compounds; Animals; Aza Compounds; Buffers; Calcium; Calcium Channel Blockers; Cell Line, T

2012
Thapsigargin selectively stimulates synthesis of phosphatidylglycerol in N1E-115 neuroblastoma cells and phosphatidylinositol in C6 glioma cells.
    Biochimica et biophysica acta, 1994, Nov-17, Volume: 1215, Issue:1-2

    Topics: Animals; Calcium; Gallic Acid; Glioma; Mice; Neuroblastoma; Oleic Acid; Oleic Acids; Phosphates; Pho

1994
Analysis of intra- and intercellular calcium signaling in a mouse malignant glioma cell line.
    Journal of neurosurgery, 1994, Volume: 81, Issue:3

    Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cytosol; Gallic Acid; Gap Junctions; G

1994