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gallic acid and Fibrosis

gallic acid has been researched along with Fibrosis in 12 studies

gallate : A trihydroxybenzoate that is the conjugate base of gallic acid.

Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.

Research Excerpts

ExcerptRelevanceReference
"Gallic acid has been reported to mitigate cardiac hypertrophy, fibrosis and arterial hypertension."8.12Syringic acid mitigates isoproterenol-induced cardiac hypertrophy and fibrosis by downregulating Ereg. ( Bai, L; Han, X; Jeong, MH; Kee, HJ, 2022)
"These results suggested that gallic acid may be a potential therapeutic agent for the treatment of cardiovascular diseases with hypertension and cardiac fibrosis."7.85Gallic acid attenuates hypertension, cardiac remodeling, and fibrosis in mice with NG-nitro-L-arginine methyl ester-induced hypertension via regulation of histone deacetylase 1 or histone deacetylase 2. ( Cho, JY; Choi, SY; Jeong, MH; Jin, L; Kee, HJ; Kim, GR; Lin, MQ; Piao, ZH; Ryu, Y; Sun, S, 2017)
"Gallic acid is a trihydroxybenzoic acid found in tea leaves and some plants."5.48Gallic acid improves cardiac dysfunction and fibrosis in pressure overload-induced heart failure. ( Choi, SY; Jeong, MH; Jin, L; Kee, HJ; Kim, GR; Kim, HS; Liu, B; Piao, ZH; Ryu, Y; Sun, S, 2018)
"Gallic acid pretreatment attenuated concentric cardiac hypertrophy."5.43Gallic acid prevents isoproterenol-induced cardiac hypertrophy and fibrosis through regulation of JNK2 signaling and Smad3 binding activity. ( Cho, JY; Choi, SY; Jeong, MH; Jin, L; Kee, HJ; Kim, GR; Lin, MQ; Piao, ZH; Ryu, Y, 2016)
"Fibrosis is one of the characteristic features of chronic kidney disease (CKD)."5.42Leonurine ameliorates kidney fibrosis via suppressing TGF-β and NF-κB signaling pathway in UUO mice. ( Bo, Y; Cheng, H; Jia, Z; Li, F; Shen, W; Tan, J; Xu, C, 2015)
"Gallic acid has been reported to mitigate cardiac hypertrophy, fibrosis and arterial hypertension."4.12Syringic acid mitigates isoproterenol-induced cardiac hypertrophy and fibrosis by downregulating Ereg. ( Bai, L; Han, X; Jeong, MH; Kee, HJ, 2022)
"These results suggested that gallic acid may be a potential therapeutic agent for the treatment of cardiovascular diseases with hypertension and cardiac fibrosis."3.85Gallic acid attenuates hypertension, cardiac remodeling, and fibrosis in mice with NG-nitro-L-arginine methyl ester-induced hypertension via regulation of histone deacetylase 1 or histone deacetylase 2. ( Cho, JY; Choi, SY; Jeong, MH; Jin, L; Kee, HJ; Kim, GR; Lin, MQ; Piao, ZH; Ryu, Y; Sun, S, 2017)
" Hence the present study was framed to investigate the protective role of Gallic acid (GA) on AGEs induced cardiac fibrosis."3.80Regulatory mechanism of gallic acid against advanced glycation end products induced cardiac remodeling in experimental rats. ( Elangovan, V; Gopi, V; Umadevi, S, 2014)
" Herein, we investigated the roles and the possible mechanisms of leonurine for reducing fibrotic responses in angiotensin II (Ang II)-stimulated primary neonatal rat cardiac fibroblasts and post-myocardial infarction (MI) rats."3.79Leonurine (SCM-198) attenuates myocardial fibrotic response via inhibition of NADPH oxidase 4. ( Deng, HY; Gong, QH; Huang, GY; Liu, XH; Pan, LL; Wu, D; Xiong, QH; Zhu, YZ, 2013)
"Gallic acid is a trihydroxybenzoic acid found in tea leaves and some plants."1.48Gallic acid improves cardiac dysfunction and fibrosis in pressure overload-induced heart failure. ( Choi, SY; Jeong, MH; Jin, L; Kee, HJ; Kim, GR; Kim, HS; Liu, B; Piao, ZH; Ryu, Y; Sun, S, 2018)
"Gallic acid pretreatment attenuated concentric cardiac hypertrophy."1.43Gallic acid prevents isoproterenol-induced cardiac hypertrophy and fibrosis through regulation of JNK2 signaling and Smad3 binding activity. ( Cho, JY; Choi, SY; Jeong, MH; Jin, L; Kee, HJ; Kim, GR; Lin, MQ; Piao, ZH; Ryu, Y, 2016)
"Fibrosis is one of the characteristic features of chronic kidney disease (CKD)."1.42Leonurine ameliorates kidney fibrosis via suppressing TGF-β and NF-κB signaling pathway in UUO mice. ( Bo, Y; Cheng, H; Jia, Z; Li, F; Shen, W; Tan, J; Xu, C, 2015)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (66.67)24.3611
2020's4 (33.33)2.80

Authors

AuthorsStudies
Han, X1
Bai, L1
Kee, HJ4
Jeong, MH4
Prasad, S1
Marks, DH1
Burns, LJ1
De Souza, B1
Flynn, EA1
Scheinman, P1
Silvestri, D1
Yu, J1
LoSicco, K1
Senna, MM1
Wang, R1
Peng, L1
Lv, D1
Shang, F1
Yan, J1
Li, G1
Li, D1
Ouyang, J1
Yang, J1
Mojadami, S1
Ahangarpour, A1
Mard, SA1
Khorsandi, L1
Jin, L3
Sun, S2
Ryu, Y3
Piao, ZH3
Liu, B1
Choi, SY3
Kim, GR3
Kim, HS1
Shahzad, S1
Mateen, S1
Naeem, SS1
Akhtar, K1
Rizvi, W1
Moin, S1
Umadevi, S1
Gopi, V1
Elangovan, V1
Cheng, H1
Bo, Y1
Shen, W1
Tan, J1
Jia, Z1
Xu, C1
Li, F1
Cho, JY2
Lin, MQ2
Peng, CC1
Hsieh, CL1
Wang, HE1
Chung, JY1
Chen, KC1
Peng, RY1
Liu, XH1
Pan, LL1
Deng, HY1
Xiong, QH1
Wu, D1
Huang, GY1
Gong, QH1
Zhu, YZ1

Other Studies

12 other studies available for gallic acid and Fibrosis

ArticleYear
Syringic acid mitigates isoproterenol-induced cardiac hypertrophy and fibrosis by downregulating Ereg.
    Journal of cellular and molecular medicine, 2022, Volume: 26, Issue:14

    Topics: Animals; Cardiomegaly; Fibrosis; Gallic Acid; Isoproterenol; Mice; Myocardium

2022
Patch testing and contact allergen avoidance in patients with lichen planopilaris and/or frontal fibrosing alopecia: A cohort study.
    Journal of the American Academy of Dermatology, 2020, Volume: 83, Issue:2

    Topics: Acyclic Monoterpenes; Adult; Aged; Aged, 80 and over; Allergens; Alopecia; Biopsy; Cohort Studies; C

2020
Leonurine Attenuates Myocardial Fibrosis Through Upregulation of miR-29a-3p in Mice Post-myocardial Infarction.
    Journal of cardiovascular pharmacology, 2021, 02-01, Volume: 77, Issue:2

    Topics: Angiotensin II; Animals; Cell Movement; Cell Proliferation; Cells, Cultured; Collagen; Disease Model

2021
Diabetic nephropathy induced by methylglyoxal: gallic acid regulates kidney microRNAs and glyoxalase1-Nrf2 in male mice.
    Archives of physiology and biochemistry, 2023, Volume: 129, Issue:3

    Topics: Animals; Diabetes Mellitus; Diabetic Nephropathies; Fibrosis; Gallic Acid; Kidney; Male; Mice; Micro

2023
Gallic acid improves cardiac dysfunction and fibrosis in pressure overload-induced heart failure.
    Scientific reports, 2018, 06-18, Volume: 8, Issue:1

    Topics: Animals; Aorta; Biomarkers; Cardiomegaly; Constriction, Pathologic; Fibrosis; Gallic Acid; Gene Expr

2018
Syringic acid protects from isoproterenol induced cardiotoxicity in rats.
    European journal of pharmacology, 2019, Apr-15, Volume: 849

    Topics: Adenosine Triphosphatases; Animals; Biomarkers; Biphenyl Compounds; Body Weight; Cardiotoxicity; Cyt

2019
Regulatory mechanism of gallic acid against advanced glycation end products induced cardiac remodeling in experimental rats.
    Chemico-biological interactions, 2014, Feb-05, Volume: 208

    Topics: Animals; Biomarkers; Body Weight; Fibrosis; Gallic Acid; Glycation End Products, Advanced; Heart; Ma

2014
Leonurine ameliorates kidney fibrosis via suppressing TGF-β and NF-κB signaling pathway in UUO mice.
    International immunopharmacology, 2015, Volume: 25, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Epithelial-Mesenchymal Transit

2015
Gallic acid prevents isoproterenol-induced cardiac hypertrophy and fibrosis through regulation of JNK2 signaling and Smad3 binding activity.
    Scientific reports, 2016, 10-05, Volume: 6

    Topics: Animals; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Fibrosis; Gallic Acid; Gene Expressi

2016
Gallic acid attenuates hypertension, cardiac remodeling, and fibrosis in mice with NG-nitro-L-arginine methyl ester-induced hypertension via regulation of histone deacetylase 1 or histone deacetylase 2.
    Journal of hypertension, 2017, Volume: 35, Issue:7

    Topics: Animals; Blood Pressure; Fibrosis; Gallic Acid; Heart Ventricles; Histone Deacetylase 1; Histone Dea

2017
Ferulic acid is nephrodamaging while gallic acid is renal protective in long term treatment of chronic kidney disease.
    Clinical nutrition (Edinburgh, Scotland), 2012, Volume: 31, Issue:3

    Topics: Animals; Antioxidants; Collagen; Coumaric Acids; Dietary Supplements; Disease Models, Animal; Fibros

2012
Leonurine (SCM-198) attenuates myocardial fibrotic response via inhibition of NADPH oxidase 4.
    Free radical biology & medicine, 2013, Volume: 54

    Topics: Angiotensin II; Animals; Cells, Cultured; Down-Regulation; Extracellular Signal-Regulated MAP Kinase

2013