Page last updated: 2024-10-17

gallic acid and Disease Models, Animal

gallic acid has been researched along with Disease Models, Animal in 119 studies

gallate : A trihydroxybenzoate that is the conjugate base of gallic acid.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"This study investigated the ameliorative effect of gallic acid (GA) on hypertriglyceridemia and fat accumulation in perirenal adipose tissues of high-fructose diet (HFD)-induced diabetic rats."7.88Gallic Acid Alleviates Hypertriglyceridemia and Fat Accumulation via Modulating Glycolysis and Lipolysis Pathways in Perirenal Adipose Tissues of Rats Fed a High-Fructose Diet. ( Chang, WC; Huang, DW; Shen, SC; Wu, JS; Yang, HJ, 2018)
" The present study was intended to appraise the nutraceutical inherent of HPLC standardized Spinacia oleracea methanolic leaf extract (SoLE) in isoproterenol (ISO) induced male albino Wistar rats via activation of pro-inflammatory signaling pathway that drives myocardial necrosis."7.85Nutraceutical inherent of Spinacia oleracea Linn. methanolic leaf extract ameliorates isoproterenol induced myocardial necrosis in male albino Wistar rats via mitigating inflammation. ( Jolapuram, U; Kodidhela, LD; Vutharadhi, S, 2017)
"In the relevant literature, there is no experimental study that investigated the axon protective effects of syringic acid- a polyphenol compound- with an anti-oxidant capacity on ischemia/reperfusion injury."7.85The Axon Protective Effects of Syringic Acid on Ischemia/Reperfusion Injury in a Rat Sciatic Nerve Model. ( Akman, T; Albayrak, SB; Aras, AB; Cosar, M; Gomleksiz, C; Guven, M; Sehitoglu, MH; Tokmak, M; Yaka, U; Yuksel, Y, 2017)
"Administration of leonurine (60 mg/kg) for 4 weeks significantly alleviated depression-like behaviors of chronic mild stress mice, including increased sucrose preference and reduced immobility time in forced swimming test and tail suspension test."7.85Leonurine Exerts Antidepressant-Like Effects in the Chronic Mild Stress-Induced Depression Model in Mice by Inhibiting Neuroinflammation. ( Chen, M; Ding, J; Ding, X; Du, R; Hu, G; Jia, M; Li, C; Lu, M; Zheng, Y, 2017)
"These findings suggest that leonurine ameliorates cognitive dysfunction at least partly via antagonizing excitotoxic glutamate insults and inhibiting autophagy."7.83Leonurine ameliorates cognitive dysfunction via antagonizing excitotoxic glutamate insults and inhibiting autophagy. ( Gao, J; Liu, C; Xu, X; Yang, Z; Yin, H; Zhang, T, 2016)
"Combined administration of gigantol and SA synergize to enhance anti-cataract efficacy."7.83Investigation of synergistic mechanism and identification of interaction site of aldose reductase with the combination of gigantol and syringic acid for prevention of diabetic cataract. ( Chen, CY; Chen, D; Fang, H; Gao, X; Li, X; Long, Y; Wei, X; Wu, J; Yi, Y, 2016)
"Chronic treatment with trimethylgallic acid esters for 15 days significantly reversed the chronic stress-induced behavioral (impaired locomotor activity, anxiety-like behavior, and decreased percentage of memory retention), biochemical (increased lipid peroxidation and nitrite levels; decreased glutathione levels, superoxide dismutase and catalase activities), and inflammation surge (serum TNF-α) in stressed mice."7.80Effect of trimethylgallic acid esters against chronic stress-induced anxiety-like behavior and oxidative stress in mice. ( Chadha, R; Dhingra, MS; Dhingra, S; Karan, M; Kumar, A; Kumria, R; Singh, T, 2014)
"Leonurine significantly alleviated neurological deficit, decreased brain water content and infarct volume after ischemic stroke, which was accompanied by decreased levels of MDA and Bax, increased activities of SOD, CAT, UCP4, and Bcl-2, and restored ultrastructure of mitochondria."7.78Leonurine protects brain injury by increased activities of UCP4, SOD, CAT and Bcl-2, decreased levels of MDA and Bax, and ameliorated ultrastructure of mitochondria in experimental stroke. ( Cao, X; Dong, L; Du, Y; Ji, H; Ji, Y; Li, L; Li, S; Liu, H; Wang, C; Xing, Y; Zhang, X; Zhao, K, 2012)
" This study was designed to evaluate the protective effect of gallic acid on cardiac marker enzymes, troponin-T, LDH-isoenzyme pattern, lipid peroxidation products and antioxidant status in isoproterenol (ISO)-induced myocardial infarction in male Wistar rats."7.75Cardioprotective effect of gallic acid on cardiac troponin-T, cardiac marker enzymes, lipid peroxidation products and antioxidants in experimentally induced myocardial infarction in Wistar rats. ( Prince, PS; Priscilla, DH, 2009)
"Leonurine treatment significantly inhibited the mortality caused by H1N1 infection."5.62Leonurine protects against influenza A virus infection-induced pneumonia in mice. ( Chen, XJ; Luo, YJ; Qiu, LN; Tan, YR, 2021)
"Octyl gallate (OG) is a phenolic compound with therapeutic actions namely antimicrobial, antiviral, and antifungal."5.56Anti-inflammatory effect of octyl gallate in alveolar macrophages cells and mice with acute lung injury. ( Antunes, GL; da Costa, MS; de Oliveira, JR; de Souza Basso, B; Donadio, MVF; Gracia-Sancho, J; Haute, GV; Kaiber, DB; Levorse, VGS; Luft, C; Silveira, JS, 2020)
"Gastric ulcers were induced by absolute ethanol (5 mL/kg, i."5.56Gastroprotective effect of gallic acid against ethanol-induced gastric ulcer in rats: Involvement of the Nrf2/HO-1 signaling and anti-apoptosis role. ( Chang, Y; Duan, LR; Li, H; Li, Y; Tian, T; Wang, SW; Yang, Q; Zhou, D, 2020)
"Gallic acid is an active phenolic acid widely distributed in plants, and there is compelling evidence to prove its anti-inflammatory effects."5.56Gallic Acid Alleviates Gouty Arthritis by Inhibiting NLRP3 Inflammasome Activation and Pyroptosis Through Enhancing Nrf2 Signaling. ( Chen, D; Fu, Z; Huang, X; Li, X; Li, Y; Lin, Y; Liu, A; Luo, T; Pan, H; Weng, A; Yao, Y, 2020)
"cholerae was studied by performing histology in Swiss albino mice."5.51In vivo fluid accumulation-inhibitory, anticolonization and anti-inflammatory and in vitro biofilm-inhibitory activities of methyl gallate isolated from Terminalia chebula against fluoroquinolones resistant Vibrio cholerae. ( Acharyya, S; Bag, PK; Bhowmik, P; Koley, H; Roy, N; Saha, DR; Sarkar, P, 2019)
"However, the effects of GA on ulcerative colitis (UC) remain unknown."5.51Gallic acid improved inflammation via NF-κB pathway in TNBS-induced ulcerative colitis. ( Gu, P; Shen, H; Zhu, L, 2019)
"Neurodegenerative diseases comprise demyelination and synaptic loss."5.51Gallic and vanillic acid suppress inflammation and promote myelination in an in vitro mouse model of neurodegeneration. ( Jamali, KS; Kamal, A; Khan, F; Saify, ZS; Siddiqui, S, 2019)
" The QUIN is involved in the development of several toxic cascades which leads to the neuronal degeneration processes."5.48Effect of wedelolactone and gallic acid on quinolinic acid-induced neurotoxicity and impaired motor function: significance to sporadic amyotrophic lateral sclerosis. ( Goli, D; S, M; T, P, 2018)
"Endometritis is the inflammation of the endometrium that is associated with lower conception rates, increased intervals from calving to first service, and more culls for failure to conceive, which leads to serious economic losses in the dairy industry."5.48Leonurine ameliorates the inflammatory responses in lipopolysaccharide-induced endometritis. ( Chen, X; Dai, A; Deng, G; Huang, C; Jiang, K; Li, X; Wu, H; Yang, X, 2018)
"Leonurine is a compound derived from Herba leonuri, which has been reported to protect cardiac tissue against ischemic injury via antioxidant and anti‑apoptosis effects."5.48Leonurine protects cardiac function following acute myocardial infarction through anti‑apoptosis by the PI3K/AKT/GSK3β signaling pathway. ( Jiang, X; Wei, F; Xu, L; Zhu, H, 2018)
"Cardiac hypertrophy was induced by isoproterenol (ISP) in mice and primary neonatal cardiomyocytes."5.43Gallic acid prevents isoproterenol-induced cardiac hypertrophy and fibrosis through regulation of JNK2 signaling and Smad3 binding activity. ( Cho, JY; Choi, SY; Jeong, MH; Jin, L; Kee, HJ; Kim, GR; Lin, MQ; Piao, ZH; Ryu, Y, 2016)
"Gallic acid (GA) is a polyhydroxy phenolic compound that has been detected in various natural products, such as green tea, strawberries, grapes, bananas, and many other fruits."5.42Gallic acid attenuates dextran sulfate sodium-induced experimental colitis in BALB/c mice. ( Looi, CY; Mohebali, N; Norhaizan, ME; Pandurangan, AK, 2015)
"Fibrosis is one of the characteristic features of chronic kidney disease (CKD)."5.42Leonurine ameliorates kidney fibrosis via suppressing TGF-β and NF-κB signaling pathway in UUO mice. ( Bo, Y; Cheng, H; Jia, Z; Li, F; Shen, W; Tan, J; Xu, C, 2015)
"Hypertension was induced in adult male albino rats by oral administration of L-NAME (40 mg/kg/day) dissolved in drinking water daily for 4 weeks."5.38Syringic acid ameliorates (L)-NAME-induced hypertension by reducing oxidative stress. ( Kumar, S; Prahalathan, P; Raja, B, 2012)
"Hyperlipidemia is the major risk factors of heart disease such as atherosclerosis, stroke, and death."5.35Comparison of hypolipidemic activity of synthetic gallic acid-linoleic acid ester with mixture of gallic acid and linoleic acid, gallic acid, and linoleic acid on high-fat diet induced obesity in C57BL/6 Cr Slc mice. ( Jang, A; Jo, C; Lee, JW; Lee, M; Lee, NY; Song, HP; Srinivasan, P, 2008)
"This study investigated the ameliorative effect of gallic acid (GA) on hypertriglyceridemia and fat accumulation in perirenal adipose tissues of high-fructose diet (HFD)-induced diabetic rats."3.88Gallic Acid Alleviates Hypertriglyceridemia and Fat Accumulation via Modulating Glycolysis and Lipolysis Pathways in Perirenal Adipose Tissues of Rats Fed a High-Fructose Diet. ( Chang, WC; Huang, DW; Shen, SC; Wu, JS; Yang, HJ, 2018)
" The present study was intended to appraise the nutraceutical inherent of HPLC standardized Spinacia oleracea methanolic leaf extract (SoLE) in isoproterenol (ISO) induced male albino Wistar rats via activation of pro-inflammatory signaling pathway that drives myocardial necrosis."3.85Nutraceutical inherent of Spinacia oleracea Linn. methanolic leaf extract ameliorates isoproterenol induced myocardial necrosis in male albino Wistar rats via mitigating inflammation. ( Jolapuram, U; Kodidhela, LD; Vutharadhi, S, 2017)
"In the relevant literature, there is no experimental study that investigated the axon protective effects of syringic acid- a polyphenol compound- with an anti-oxidant capacity on ischemia/reperfusion injury."3.85The Axon Protective Effects of Syringic Acid on Ischemia/Reperfusion Injury in a Rat Sciatic Nerve Model. ( Akman, T; Albayrak, SB; Aras, AB; Cosar, M; Gomleksiz, C; Guven, M; Sehitoglu, MH; Tokmak, M; Yaka, U; Yuksel, Y, 2017)
"Administration of leonurine (60 mg/kg) for 4 weeks significantly alleviated depression-like behaviors of chronic mild stress mice, including increased sucrose preference and reduced immobility time in forced swimming test and tail suspension test."3.85Leonurine Exerts Antidepressant-Like Effects in the Chronic Mild Stress-Induced Depression Model in Mice by Inhibiting Neuroinflammation. ( Chen, M; Ding, J; Ding, X; Du, R; Hu, G; Jia, M; Li, C; Lu, M; Zheng, Y, 2017)
"These findings suggest that leonurine ameliorates cognitive dysfunction at least partly via antagonizing excitotoxic glutamate insults and inhibiting autophagy."3.83Leonurine ameliorates cognitive dysfunction via antagonizing excitotoxic glutamate insults and inhibiting autophagy. ( Gao, J; Liu, C; Xu, X; Yang, Z; Yin, H; Zhang, T, 2016)
"Combined administration of gigantol and SA synergize to enhance anti-cataract efficacy."3.83Investigation of synergistic mechanism and identification of interaction site of aldose reductase with the combination of gigantol and syringic acid for prevention of diabetic cataract. ( Chen, CY; Chen, D; Fang, H; Gao, X; Li, X; Long, Y; Wei, X; Wu, J; Yi, Y, 2016)
" Gallic acid (GA) and its derivatives were reported to be effective in treatment of arthritis."3.80Effect of JEZTC, a synthetic compound, on proliferation and phenotype maintenance of rabbit articular chondrocytes in vitro. ( Lin, X; Liu, L; Liu, Q; Wei, QJ; Zheng, L, 2014)
"Chronic treatment with trimethylgallic acid esters for 15 days significantly reversed the chronic stress-induced behavioral (impaired locomotor activity, anxiety-like behavior, and decreased percentage of memory retention), biochemical (increased lipid peroxidation and nitrite levels; decreased glutathione levels, superoxide dismutase and catalase activities), and inflammation surge (serum TNF-α) in stressed mice."3.80Effect of trimethylgallic acid esters against chronic stress-induced anxiety-like behavior and oxidative stress in mice. ( Chadha, R; Dhingra, MS; Dhingra, S; Karan, M; Kumar, A; Kumria, R; Singh, T, 2014)
" The purpose of the present work was to characterize the interaction and investigate the protective effect of H2 blocker famotidine and gallic acid in combination against experimentally induced peptic ulcer."3.80Synergistic effect of the combination of gallic acid and famotidine in protection of rat gastric mucosa. ( Asokkumar, K; Sen, S; Sivashanmugam, AT; Subhadradevi, V; Umamaheswari, M, 2014)
"Leonurine significantly alleviated neurological deficit, decreased brain water content and infarct volume after ischemic stroke, which was accompanied by decreased levels of MDA and Bax, increased activities of SOD, CAT, UCP4, and Bcl-2, and restored ultrastructure of mitochondria."3.78Leonurine protects brain injury by increased activities of UCP4, SOD, CAT and Bcl-2, decreased levels of MDA and Bax, and ameliorated ultrastructure of mitochondria in experimental stroke. ( Cao, X; Dong, L; Du, Y; Ji, H; Ji, Y; Li, L; Li, S; Liu, H; Wang, C; Xing, Y; Zhang, X; Zhao, K, 2012)
"The aim of this study was evaluation the effect of Gallic acid on movement disorders and pallidal electrical power in animal model of Parkinson's Disease (PD)."3.77Motor disorders and impaired electrical power of pallidal EEG improved by gallic acid in animal model of Parkinson's disease. ( Farbood, Y; Mansouri, SM; Sameri, MJ; Sarkaki, A, 2011)
" This study was designed to evaluate the protective effect of gallic acid on cardiac marker enzymes, troponin-T, LDH-isoenzyme pattern, lipid peroxidation products and antioxidant status in isoproterenol (ISO)-induced myocardial infarction in male Wistar rats."3.75Cardioprotective effect of gallic acid on cardiac troponin-T, cardiac marker enzymes, lipid peroxidation products and antioxidants in experimentally induced myocardial infarction in Wistar rats. ( Prince, PS; Priscilla, DH, 2009)
"Male Sprague-Dawley rats under permanent middle cerebral artery occlusion (pMCAO) model, randomly assigned as: model, sham, nimodipine (0."3.11The therapeutic role of Jingchuan tablet on ischaemic cerebral stroke via the HIF-1α/EPO/VEGFA signalling pathway. ( Fu, Y; Li, D; Liu, Q; Wang, H; Wang, W; Zhang, T; Zhang, Y, 2022)
"The neuropathology of Parkinson's disease (PD) is complex and affects multiple systems of the body beyond the central nervous system."1.91The effects of gallic acid and vagotomy on motor function, intestinal transit, brain electrophysiology and oxidative stress alterations in a rat model of Parkinson's disease induced by rotenone. ( Bavarsad, K; Farbood, Y; Mard, SA; Sarkaki, A; Sheikhpour, E, 2023)
"Ethyl gallate was the lead compound and anti-inflammatory active ingredient in Galla chinensis."1.72Stepwise tracking strategy to screen ingredient from Galla Chinensis based on the "mass spectrometry guided preparative chromatography coupled with systems pharmacology". ( Chen, W; Han, B; Lv, M; Qi, Y; Tian, X; Wang, X; Wang, Z; Xie, Z; Xue, R; Yu, W, 2022)
"Pretreatment with gallic acid and lithium prevented hyperlocomotion and brain oxidative damage."1.62Gallic acid protects cerebral cortex, hippocampus, and striatum against oxidative damage and cholinergic dysfunction in an experimental model of manic-like behavior: Comparison with lithium effects. ( Bona, NP; de Mattos, BDS; Gamaro, GD; Pedra, NS; Recart, VM; Soares, MSP; Spanevello, R; Spohr, L; Stefanello, F; Teixeira, FC, 2021)
"The highest alveolar bone loss was observed in the periodontitis group."1.623,4,5-Trihydroxybenzoic Acid Attenuates Ligature-Induced Periodontal Disease in Wistar Rats. ( Gevrek, F; Karatas, O, 2021)
"Leonurine treatment significantly inhibited the mortality caused by H1N1 infection."1.62Leonurine protects against influenza A virus infection-induced pneumonia in mice. ( Chen, XJ; Luo, YJ; Qiu, LN; Tan, YR, 2021)
"Gallic acid is an active phenolic acid widely distributed in plants, and there is compelling evidence to prove its anti-inflammatory effects."1.56Gallic Acid Alleviates Gouty Arthritis by Inhibiting NLRP3 Inflammasome Activation and Pyroptosis Through Enhancing Nrf2 Signaling. ( Chen, D; Fu, Z; Huang, X; Li, X; Li, Y; Lin, Y; Liu, A; Luo, T; Pan, H; Weng, A; Yao, Y, 2020)
"Bisphenol A (BPA) has been reported that among other male reproductive dys-functions, it can cause marked estrogenic effects including alteration in serum hormones as well as testicular lesions in exposed animals."1.56Chronic exposure of adult male Wistar rats to bisphenol A causes testicular oxidative stress: Role of gallic acid. ( Lanipekun, DO; Oke, BO; Ola-Davies, EO; Olukole, SG, 2020)
"Gastric ulcers were induced by absolute ethanol (5 mL/kg, i."1.56Gastroprotective effect of gallic acid against ethanol-induced gastric ulcer in rats: Involvement of the Nrf2/HO-1 signaling and anti-apoptosis role. ( Chang, Y; Duan, LR; Li, H; Li, Y; Tian, T; Wang, SW; Yang, Q; Zhou, D, 2020)
"Octyl gallate (OG) is a phenolic compound with therapeutic actions namely antimicrobial, antiviral, and antifungal."1.56Anti-inflammatory effect of octyl gallate in alveolar macrophages cells and mice with acute lung injury. ( Antunes, GL; da Costa, MS; de Oliveira, JR; de Souza Basso, B; Donadio, MVF; Gracia-Sancho, J; Haute, GV; Kaiber, DB; Levorse, VGS; Luft, C; Silveira, JS, 2020)
"d-galactose (d-gal) can cause damages that resemble accelerated aging in mice."1.56Gallic acid attenuates thymic involution in the d-galactose induced accelerated aging mice. ( Cao, JH; Chai, YR; Feng, YK; Guo, L; Li, JH; Sun, Y; Wang, LP; Wei, TT, 2020)
"and gallic acid were evaluated in experimentally induced hyperglycemic animals."1.51Wound healing activity of Terminalia bellerica Roxb. and gallic acid in experimentally induced diabetic animals. ( Gupta, A; Singh, MP; Sisodia, SS, 2019)
" This study indicated the potential of phospholipids in promoting the bioavailability of EGCG3''Me and might contribute to the production of functional food with better tea catechins absorption."1.51The regulation effect of EGCG3''Me phospholipid complex on gut flora of a high-fat diet-induced obesity mouse model. ( Cheng, L; Lin, Y; Yang, H; Zhang, X, 2019)
"cholerae was studied by performing histology in Swiss albino mice."1.51In vivo fluid accumulation-inhibitory, anticolonization and anti-inflammatory and in vitro biofilm-inhibitory activities of methyl gallate isolated from Terminalia chebula against fluoroquinolones resistant Vibrio cholerae. ( Acharyya, S; Bag, PK; Bhowmik, P; Koley, H; Roy, N; Saha, DR; Sarkar, P, 2019)
"Neurodegenerative diseases comprise demyelination and synaptic loss."1.51Gallic and vanillic acid suppress inflammation and promote myelination in an in vitro mouse model of neurodegeneration. ( Jamali, KS; Kamal, A; Khan, F; Saify, ZS; Siddiqui, S, 2019)
"However, the effects of GA on ulcerative colitis (UC) remain unknown."1.51Gallic acid improved inflammation via NF-κB pathway in TNBS-induced ulcerative colitis. ( Gu, P; Shen, H; Zhu, L, 2019)
"Endometritis is the inflammation of the endometrium that is associated with lower conception rates, increased intervals from calving to first service, and more culls for failure to conceive, which leads to serious economic losses in the dairy industry."1.48Leonurine ameliorates the inflammatory responses in lipopolysaccharide-induced endometritis. ( Chen, X; Dai, A; Deng, G; Huang, C; Jiang, K; Li, X; Wu, H; Yang, X, 2018)
"Leonurine is a compound derived from Herba leonuri, which has been reported to protect cardiac tissue against ischemic injury via antioxidant and anti‑apoptosis effects."1.48Leonurine protects cardiac function following acute myocardial infarction through anti‑apoptosis by the PI3K/AKT/GSK3β signaling pathway. ( Jiang, X; Wei, F; Xu, L; Zhu, H, 2018)
"Gallic acid was evaluated for its possible effect at the dose of 20 and 40 mg/kg body weight."1.48Gallic acid attenuates type I diabetic nephropathy in rats. ( Garud, MS; Kulkarni, YA, 2018)
"Gallic acid has been reported to possess a number of psychopharmacological activities."1.48Protective effect of gallic acid in experimental model of ketamine-induced psychosis: possible behaviour, biochemical, neurochemical and cellular alterations. ( Dhingra, MS; Dhingra, S; Jindal, DK; Kumar, A; Parle, M; Yadav, M, 2018)
" The QUIN is involved in the development of several toxic cascades which leads to the neuronal degeneration processes."1.48Effect of wedelolactone and gallic acid on quinolinic acid-induced neurotoxicity and impaired motor function: significance to sporadic amyotrophic lateral sclerosis. ( Goli, D; S, M; T, P, 2018)
"Syringic acid (SA) is a phenolic compound present in the fruit of the açaí palm Euterpe oleracea and the mycelium of the shiitake mushroom Lentinula edodes."1.46Antiosteoporotic activity of a syringic acid diet in ovariectomized mice. ( Fukuta, Y; Kawaguchi, N; Moriyama, T; Shirasaka, N; Tanaka, T; Zaima, N, 2017)
"To date, there is no effective Alzheimer's disease (AD)-modifying therapy."1.46Combination therapy with octyl gallate and ferulic acid improves cognition and neurodegeneration in a transgenic mouse model of Alzheimer's disease. ( Koyama, N; Maeda, M; Mori, T; Segawa, T; Tan, J; Town, T, 2017)
"Cardiac hypertrophy was induced by isoproterenol (ISP) in mice and primary neonatal cardiomyocytes."1.43Gallic acid prevents isoproterenol-induced cardiac hypertrophy and fibrosis through regulation of JNK2 signaling and Smad3 binding activity. ( Cho, JY; Choi, SY; Jeong, MH; Jin, L; Kee, HJ; Kim, GR; Lin, MQ; Piao, ZH; Ryu, Y, 2016)
"Fibrosis is one of the characteristic features of chronic kidney disease (CKD)."1.42Leonurine ameliorates kidney fibrosis via suppressing TGF-β and NF-κB signaling pathway in UUO mice. ( Bo, Y; Cheng, H; Jia, Z; Li, F; Shen, W; Tan, J; Xu, C, 2015)
"Gallic acid (GA) is a polyhydroxy phenolic compound that has been detected in various natural products, such as green tea, strawberries, grapes, bananas, and many other fruits."1.42Gallic acid attenuates dextran sulfate sodium-induced experimental colitis in BALB/c mice. ( Looi, CY; Mohebali, N; Norhaizan, ME; Pandurangan, AK, 2015)
"Gallic acid was given 15 mins before ischemia induction."1.40The examination of protective effects of gallic acid against damage of oxidative stress during induced-experimental renal ischemia-reperfusion in experiment. ( Bayramoglu, G; Canbek, M; Ceyhan, E; Durmus, B; Kanbak, G; Kartkaya, K; Ozen, A; Oztopcu Vatan, AP; Senturk, H; Uyanoglu, M, 2014)
" Furthermore, chronic administration of GA significantly restored the spatial memory, total thiol and GPx contents and also decreased MDA levels in these tissues."1.40Protective effects of gallic acid against chronic cerebral hypoperfusion-induced cognitive deficit and brain oxidative damage in rats. ( Farbood, Y; Fathi Moghaddam, H; Korani, MS; Sarkaki, A; Taghi Mansouri, M, 2014)
"Gallic acid is a natural polyphenolic acid found in gall nuts, sumac, oak bark, tea leaves, grapes and wine, with potent antioxidant and antiapoptotic activity."1.39Gallic acid decreases vacuous chewing movements induced by reserpine in rats. ( Bürger, ME; de Freitas, CM; Fachinetto, R; Ferrari, MC; Peroza, LR; Reckziegel, P; Schaffer, LF, 2013)
"Vasopressor therapy is required in septic shock to maintain tissue perfusion in the face of hypotension."1.38Benefits of ethyl gallate versus norepinephrine in the treatment of cardiovascular collapse in Pseudomonas aeruginosa septic shock in dogs. ( Cheng, ZQ; Gotes, J; Jacobs, H; Kasian, K; Mink, SN, 2012)
"Hypertension was induced in adult male albino rats by oral administration of L-NAME (40 mg/kg/day) dissolved in drinking water daily for 4 weeks."1.38Syringic acid ameliorates (L)-NAME-induced hypertension by reducing oxidative stress. ( Kumar, S; Prahalathan, P; Raja, B, 2012)
"Gallic acid content was 0."1.36Antiinflammatory and antioxidant activities of gum mastic. ( Ebrahimzadeh, MA; Eslami, Sh; Hafezi, S; Mahmoudi, M; Nabavi, SF; Nabavi, SM, 2010)
"Hyperlipidemia is the major risk factors of heart disease such as atherosclerosis, stroke, and death."1.35Comparison of hypolipidemic activity of synthetic gallic acid-linoleic acid ester with mixture of gallic acid and linoleic acid, gallic acid, and linoleic acid on high-fat diet induced obesity in C57BL/6 Cr Slc mice. ( Jang, A; Jo, C; Lee, JW; Lee, M; Lee, NY; Song, HP; Srinivasan, P, 2008)
"Pretreatment with gallic acid (15 mg/kg) to isoproterenol treated rats significantly (P<0."1.35Gallic acid prevents lysosomal damage in isoproterenol induced cardiotoxicity in Wistar rats. ( Devika, PT; Priscilla, H; Stanely Mainzen Prince, P, 2009)
"Luteolin was found histologically to suppress inflammation in lung tissue, the development of C."1.33In vivo treatment of acute Chlamydia pneumoniae infection with the flavonoids quercetin and luteolin and an alkyl gallate, octyl gallate, in a mouse model. ( Leinonen, M; Saario, E; Saikku, P; Törmäkangas, L; Vuorela, H; Vuorela, P, 2005)
"ETEC-induced diarrhea is initiated by the binding of B subunit of heat-labile enterotoxin (LTB) to the ganglioside G(M1) on the surface of intestinal epithelial cell."1.33Anti-diarrheal effect of Galla Chinensis on the Escherichia coli heat-labile enterotoxin and ganglioside interaction. ( Chang, YS; Chen, JC; Ho, TY; Hsiang, CY; Wu, SL, 2006)
" The 500 mg/kg GSH ester reduced hearing loss and OHC loss, but protection decreased as dosage increased, suggesting possible toxicity."1.32Glutathione ester but not glutathione protects against cisplatin-induced ototoxicity in a rat model. ( Campbell, KC; Hughes, LF; Larsen, DL; Meech, RP; Rybak, LP, 2003)
"Acute myocardial ischemia was induced in anesthetized cats by a 60-min occlusion of the left anterior descending coronary artery (LAD)."1.31Differential acetylcholine release mechanisms in the ischemic and non-ischemic myocardium. ( Akiyama, T; Inagaki, M; Kawada, T; Sato, T; Shishido, T; Sugimachi, M; Sunagawa, K; Takaki, H; Yamazaki, T, 2000)

Research

Studies (119)

TimeframeStudies, this research(%)All Research%
pre-19901 (0.84)18.7374
1990's1 (0.84)18.2507
2000's14 (11.76)29.6817
2010's79 (66.39)24.3611
2020's24 (20.17)2.80

Authors

AuthorsStudies
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Qiu, LN1
Tan, YR1
Luo, YJ1
Chen, XJ1
Wang, Z1
Xue, R1
Lv, M1
Qi, Y1
Yu, W1
Xie, Z2
Chen, W1
Wang, X3
Tian, X2
Han, B2
Qi, L1
Chen, X3
Pan, Y1
Zha, Z1
Tang, M1
Shi, C1
Yang, B1
Wang, H2
Zhou, D2
Wu, Y1
Yan, H1
Shen, T1
Li, S2
Gong, J1
Li, G2
Mai, H1
Wang, D1
Tan, X1
Zhang, Y4
Liu, Q3
Zhang, T2
Fu, Y1
Wang, W1
Li, D2
Luan, S1
Peng, X1
Lin, J1
Zhan, L1
Yin, J1
Luan, J1
Ji, X1
Zhao, G1
Sheikhpour, E1
Mard, SA1
Farbood, Y4
Bavarsad, K1
Sarkaki, A4
Liu, S1
Li, J1
Feng, LH1
Singh, MP1
Gupta, A1
Sisodia, SS1
Madzuki, IN1
Lau, SF1
Mohamad Shalan, NAA1
Mohd Ishak, NI1
Mohamed, S1
Guo, L1
Cao, JH1
Wei, TT1
Li, JH1
Feng, YK1
Wang, LP1
Sun, Y1
Chai, YR1
Tanaka, M1
Sugama, A1
Sumi, K1
Shimizu, K1
Kishimoto, Y1
Kondo, K1
Iida, K1
Haute, GV1
Luft, C1
Antunes, GL1
Silveira, JS1
de Souza Basso, B1
da Costa, MS1
Levorse, VGS1
Kaiber, DB1
Donadio, MVF1
Gracia-Sancho, J1
de Oliveira, JR1
Karatas, O1
Gevrek, F1
Yang, Q1
Tian, T1
Chang, Y1
Li, Y4
Duan, LR1
Li, H1
Wang, SW1
Olukole, SG1
Ola-Davies, EO1
Lanipekun, DO1
Oke, BO1
Mori, T2
Koyama, N2
Yokoo, T1
Segawa, T2
Maeda, M2
Sawmiller, D1
Tan, J3
Town, T2
Zhuang, G1
Wang, YQ1
Li, SJ1
Jiang, X2
Wang, XY1
Wang, R1
Peng, L1
Lv, D1
Shang, F1
Yan, J1
Ouyang, J1
Yang, J1
Lin, Y2
Luo, T1
Weng, A1
Huang, X1
Yao, Y1
Fu, Z1
Liu, A1
Li, X4
Chen, D2
Pan, H1
Recart, VM2
Spohr, L2
Soares, MSP2
de Mattos, BDS1
Bona, NP1
Pedra, NS1
Teixeira, FC1
Gamaro, GD1
Stefanello, F1
Spanevello, R1
Liu, W2
Liu, J1
Xing, S1
Pan, X1
Wei, S1
Zhou, M1
Li, Z1
Wang, L1
Bielicki, JK1
Hong, Z1
Tang, P1
Liu, B3
Ran, C1
Yuan, C1
Lu, Y1
Duan, X1
Yang, Y1
Wu, H3
Costa, TR1
Francisco, AF1
Cardoso, FF1
Moreira-Dill, LS1
Fernandes, CAH1
Gomes, AAS1
Guimarães, CLS1
Marcussi, S1
Pereira, PS1
Oliveira, HC1
Fontes, MRM1
Silva, SL1
Zuliani, JP1
Soares, AM1
Luduvico, KP1
Stefanello, FM1
Spanevello, RM1
Pascual-Serrano, A1
Arola-Arnal, A1
Suárez-García, S1
Bravo, FI1
Suárez, M1
Arola, L1
Bladé, C1
Reyes, AWB1
Hong, TG1
Hop, HT1
Arayan, LT1
Huy, TXN1
Min, W1
Lee, HJ2
Lee, KS1
Kim, S2
Yadav, M1
Jindal, DK1
Dhingra, MS2
Kumar, A4
Parle, M1
Dhingra, S3
Tanaka, T1
Kawaguchi, N1
Zaima, N1
Moriyama, T1
Fukuta, Y1
Shirasaka, N1
Omobowale, TO2
Oyagbemi, AA2
Ajufo, UE1
Adejumobi, OA1
Ola-Davies, OE1
Adedapo, AA1
Yakubu, MA1
Schlickmann, F1
de Souza, P1
Boeing, T1
Mariano, LNB1
Steimbach, VMB1
Krueger, CMA1
da Silva, LM1
de Andrade, SF1
Cechinel-Filho, V1
Can, ÖD1
Turan, N1
Demir Özkay, Ü1
Öztürk, Y1
Jia, M1
Li, C1
Zheng, Y1
Ding, X1
Chen, M1
Ding, J2
Du, R1
Lu, M1
Hu, G1
Safaei, F1
Mehrzadi, S1
Khadem Haghighian, H1
Hosseinzadeh, A1
Nesari, A1
Dolatshahi, M1
Esmaeilizadeh, M1
Goudarzi, M1
Jin, L2
Piao, ZH2
Sun, S1
Ryu, Y2
Choi, SY2
Kim, GR2
Kim, HS1
Kee, HJ2
Jeong, MH2
Tayeby, F1
Salman, AAA1
Kamran, S1
Khaing, SL1
Salehen, NB1
Mohan, GMAD1
Garud, MS1
Kulkarni, YA1
Huang, DW1
Chang, WC1
Yang, HJ1
Wu, JS1
Shen, SC1
Wang, M2
Wang, C2
Zhang, Z1
Xu, T1
Lou, Y1
Wang, Q1
Jin, H1
Zhang, L2
Feng, Y1
Xu, H1
Mao, C1
Zhang, X5
Chen, Y2
Zhu, J2
Zhang, M1
Ho, CT1
Huang, Q1
Cao, J2
Xu, L1
Wei, F1
Zhu, H1
Dai, A1
Yang, X1
Huang, C1
Jiang, K1
Deng, G1
Singulani, JL1
Scorzoni, L1
Lourencetti, NMS1
Oliveira, LR1
Conçolaro, RS1
da Silva, PB1
Nazaré, AC1
Polaquini, CR1
Victorelli, FD1
Chorilli, M1
Regasini, LO1
Fusco Almeida, AM1
Mendes Giannini, MJS1
Pereira, MM1
de Morais, H1
Dos Santos Silva, E1
Corso, CR1
Adami, ER1
Carlos, RM1
Acco, A1
Zanoveli, JM1
S, M1
T, P1
Goli, D1
Lu, Z1
Liu, L2
Zheng, L2
Zhao, JM1
Yin, W1
Lei, Y1
Zhu, JX1
Shan, JL1
Hu, WQ1
Zeng, JX1
Shu, JC1
Liu, X1
Cao, W1
Qi, J2
Li, Q3
Zhao, M1
Chen, Z1
Huang, Z1
Wu, L1
Zhang, B1
Yuan, Y1
Xing, C1
Wu, W1
Qin, R1
Zhu, L1
Gu, P1
Shen, H1
Jin, M1
Gu, Y1
Wan, B1
Huang, J1
Xu, X2
Huang, R1
Siddiqui, S1
Kamal, A1
Khan, F1
Jamali, KS1
Saify, ZS1
Bag, PK1
Roy, N1
Acharyya, S1
Saha, DR1
Koley, H1
Sarkar, P1
Bhowmik, P1
Zhang, Q1
Nie, J1
Chen, SJ1
Fan, Y1
Piao, CH1
Hyeon, E1
Jung, SY1
Eom, JE1
Shin, HS1
Song, CH1
Chai, OH1
Gao, T1
Li, L2
Xiao, D1
Zou, B1
Lu, B1
Guo, Y1
Zhang, S1
Lin, L1
Li, P1
Liao, Q1
Cheng, L2
Yang, H1
Lee, JW2
Bae, CJ1
Choi, YJ1
Kim, SI1
Kwon, YS1
Kim, SS1
Chun, W1
Korani, MS1
Fathi Moghaddam, H1
Taghi Mansouri, M1
Kim, E1
Jung, YS1
Kim, H1
Kim, JS1
Park, M1
Jeong, J1
Lee, SK1
Yoon, HG1
Hwang, GS1
Namkoong, K1
Asokkumar, K1
Sen, S1
Umamaheswari, M1
Sivashanmugam, AT1
Subhadradevi, V1
Kumria, R1
Chadha, R2
Singh, T2
Karan, M2
Lin, X1
Wei, QJ1
Canbek, M1
Bayramoglu, G1
Senturk, H1
Oztopcu Vatan, AP1
Uyanoglu, M1
Ceyhan, E1
Ozen, A1
Durmus, B1
Kartkaya, K1
Kanbak, G1
Yuan, FL1
Xu, RS1
Jiang, DL1
He, XL1
Su, Q1
Jin, C1
Cheng, H1
Bo, Y1
Shen, W1
Jia, Z1
Xu, C1
Li, F1
Wen, L1
Qu, TB1
Zhai, K1
Hai, Y1
Zhou, JL1
Gharib-Naseri, MK1
Badavi, M1
Mansouri, MT1
Haghparast, A1
Mirshekar, MA1
Jhang, JJ1
Lu, CC1
Ho, CY1
Cheng, YT1
Yen, GC1
Pandurangan, AK2
Mohebali, N2
Norhaizan, ME1
Looi, CY2
Esa, NM1
Ismail, S1
Saadatdoust, Z1
Ahad, A1
Ahsan, H1
Mujeeb, M1
Siddiqui, WA1
Dwivedi, GR1
Tiwari, N1
Singh, A1
Roy, S1
Negi, AS1
Pal, A1
Chanda, D1
Sharma, A2
Darokar, MP1
Upadhyaya, K1
Singh, K1
Arun, A1
Shukla, M1
Srivastava, N1
Ashraf, R1
Mahar, R1
Shukla, SK1
Sarkar, J1
Ramachandran, R1
Lal, J1
Konwar, R1
Tripathi, RP1
Sachdeva, M1
Zakaria, ZA1
Balan, T1
Azemi, AK1
Omar, MH1
Mohtarrudin, N1
Ahmad, Z1
Abdullah, MN1
Desa, MN1
Teh, LK1
Salleh, MZ1
Tsang, MS1
Jiao, D1
Chan, BC1
Hon, KL1
Leung, PC1
Lau, CB1
Wong, EC1
Chan, CK1
Lam, CW1
Wong, CK1
Zhang, TT1
Guo, HJ1
Liu, XJ1
Chu, JP1
Zhou, XD1
Lee, JH1
Oh, M1
Seok, JH1
Lee, DB1
Bae, G1
Bae, HI1
Bae, SY1
Hong, YM1
Kwon, SO1
Lee, DH1
Song, CS1
Mun, JY1
Chung, MS1
Kim, KH1
Minozzo, BR1
Lemes, BM1
Justo, ADS1
Lara, JE1
Petry, VEK1
Fernandes, D1
Belló, C1
Vellosa, JCR1
Campagnoli, EB1
Nunes, OC1
Kitagawa, RR1
Avula, B1
Khan, IA1
Beltrame, FL1
Olusoji, MJ1
Oyeyemi, OM1
Asenuga, ER1
Ajayi, OL1
Wu, J1
Fang, H1
Yi, Y1
Long, Y1
Gao, X1
Wei, X1
Chen, CY1
Tokmak, M1
Sehitoglu, MH1
Yuksel, Y1
Guven, M1
Akman, T1
Aras, AB1
Yaka, U1
Gomleksiz, C1
Albayrak, SB1
Cosar, M1
Cho, JY1
Lin, MQ1
Liu, C1
Yin, H1
Gao, J1
Yang, Z1
Vutharadhi, S1
Jolapuram, U1
Kodidhela, LD1
Baek, JM1
Kim, JY1
Lee, CH1
Yoon, KH1
Lee, MS1
Cheng, M1
Miao, Y1
Wu, Z1
Weng, P1
Jang, A1
Srinivasan, P1
Lee, NY1
Song, HP1
Lee, M1
Jo, C1
Kiran, MD1
Giacometti, A1
Cirioni, O1
Balaban, N1
Priscilla, DH1
Prince, PS1
Stanely Mainzen Prince, P1
Priscilla, H1
Devika, PT1
Loarca-Piña, G1
Mendoza, S1
Ramos-Gómez, M1
Reynoso, R1
Mahmoudi, M1
Ebrahimzadeh, MA1
Nabavi, SF1
Hafezi, S1
Nabavi, SM1
Eslami, Sh1
Hong, ZY1
Xin, H1
Zhu, YZ1
Reckziegel, P2
Dias, VT1
Benvegnú, D1
Boufleur, N1
Silva Barcelos, RC1
Segat, HJ1
Pase, CS1
Dos Santos, CM1
Flores, EM1
Bürger, ME2
Gotes, J1
Kasian, K1
Jacobs, H1
Cheng, ZQ1
Mink, SN1
Esmat, A1
Al-Abbasi, FA1
Algandaby, MM1
Moussa, AY1
Labib, RM1
Ayoub, NA1
Abdel-Naim, AB1
Peng, CC1
Hsieh, CL1
Wang, HE1
Chung, JY1
Chen, KC1
Peng, RY1
Sameri, MJ1
Mansouri, SM1
Liu, H1
Du, Y1
Ji, H1
Xing, Y1
Dong, L1
Zhao, K1
Ji, Y1
Cao, X1
Kumar, S1
Prahalathan, P1
Raja, B1
Peroza, LR1
Schaffer, LF1
Ferrari, MC1
de Freitas, CM1
Fachinetto, R1
Campbell, KC1
Larsen, DL1
Meech, RP1
Rybak, LP1
Hughes, LF1
Joseph, EK1
Khasar, SG1
Levine, JD1
Törmäkangas, L1
Vuorela, P1
Saario, E1
Leinonen, M1
Saikku, P1
Vuorela, H1
Chen, JC1
Ho, TY1
Chang, YS1
Wu, SL1
Hsiang, CY1
Galeotti, N1
Bartolini, A1
Ghelardini, C1
Kim, SH2
Park, HH1
Lee, S1
Jun, CD1
Choi, BJ1
Kim, SY1
Kim, DK1
Park, JS1
Chae, BS1
Shin, TY1
Rao, ChV1
Verma, AR1
Vijayakumar, M1
Rastogi, S1
Chiou, GC1
Hong, SJ1
Kawada, T1
Yamazaki, T2
Akiyama, T2
Sato, T1
Shishido, T1
Inagaki, M1
Takaki, H1
Sugimachi, M1
Sunagawa, K1
Kosuge, T1
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Kitanaka, S1
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Claman, HN1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Consumption of a Beverage of Chaya (Cnidoscolus Chayamansa) on Lipid Concentration, Lipid Peroxidation and Antioxidant Status of Patients With Dyslipidemia[NCT04110392]30 participants (Actual)Interventional2019-06-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for gallic acid and Disease Models, Animal

ArticleYear
Therapeutic approaches employing natural compounds and derivatives for treating bipolar disorder: emphasis on experimental models of the manic phase.
    Metabolic brain disease, 2021, Volume: 36, Issue:7

    Topics: Animals; Biological Products; Bipolar Disorder; Disease Models, Animal; Fatty Acids, Omega-3; Gallic

2021
Suppression of biofilm related, device-associated infections by staphylococcal quorum sensing inhibitors.
    The International journal of artificial organs, 2008, Volume: 31, Issue:9

    Topics: Animals; Anti-Infective Agents; Biofilms; Catheter-Related Infections; Catheters, Indwelling; Diseas

2008

Trials

1 trial available for gallic acid and Disease Models, Animal

ArticleYear
The therapeutic role of Jingchuan tablet on ischaemic cerebral stroke via the HIF-1α/EPO/VEGFA signalling pathway.
    Pharmaceutical biology, 2022, Volume: 60, Issue:1

    Topics: Animals; Brain Ischemia; Chlorogenic Acid; Disease Models, Animal; Gallic Acid; Infarction, Middle C

2022

Other Studies

116 other studies available for gallic acid and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
Leonurine protects against influenza A virus infection-induced pneumonia in mice.
    Pathogens and disease, 2021, 09-23, Volume: 79, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Gallic Acid; Gene Expression R

2021
Stepwise tracking strategy to screen ingredient from Galla Chinensis based on the "mass spectrometry guided preparative chromatography coupled with systems pharmacology".
    Journal of ethnopharmacology, 2022, Feb-10, Volume: 284

    Topics: Animals; Animals, Outbred Strains; Anti-Inflammatory Agents; Caco-2 Cells; Chromatography, High Pres

2022
Leonurine exerts a protective effect in dextran sodium sulfate-induced experimental inflammatory bowel disease mice model.
    General physiology and biophysics, 2022, Volume: 41, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Dextran Sulfate; Disease Models, Animal; Gallic Acid; Inflammator

2022
Gallic acid ameliorates calcium oxalate crystal-induced renal injury via upregulation of Nrf2/HO-1 in the mouse model of stone formation.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2022, Volume: 106

    Topics: Animals; Antioxidants; Calcium Oxalate; Disease Models, Animal; Gallic Acid; Glyoxylates; Kidney; Mi

2022
Gallic Acid Ameliorates Aspergillus Fumigatus Keratitis Through Reducing Fungal Load and Suppressing the Inflammatory Response.
    Investigative ophthalmology & visual science, 2022, 11-01, Volume: 63, Issue:12

    Topics: Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Cytokines; Disease Models, Animal;

2022
The effects of gallic acid and vagotomy on motor function, intestinal transit, brain electrophysiology and oxidative stress alterations in a rat model of Parkinson's disease induced by rotenone.
    Life sciences, 2023, Feb-15, Volume: 315

    Topics: Animals; Brain; Disease Models, Animal; Electrophysiology; Gallic Acid; Male; Neuroprotective Agents

2023
Gallic acid regulates immune response in a mouse model of rheumatoid arthritis.
    Immunity, inflammation and disease, 2023, Volume: 11, Issue:2

    Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Cytokines; Disease Models, Animal; Gallic A

2023
Wound healing activity of Terminalia bellerica Roxb. and gallic acid in experimentally induced diabetic animals.
    Journal of complementary & integrative medicine, 2019, Sep-07, Volume: 17, Issue:2

    Topics: Animals; Diabetes Mellitus, Experimental; Disease Models, Animal; Fruit; Gallic Acid; India; Plant E

2019
Does cartilage ERα overexpression correlate with osteoarthritic chondrosenescence? Indications from
    Journal of biosciences, 2019, Volume: 44, Issue:4

    Topics: Aging; Animals; Bone Development; Cartilage; Chondrocytes; Diclofenac; Disease Models, Animal; Estro

2019
Gallic acid attenuates thymic involution in the d-galactose induced accelerated aging mice.
    Immunobiology, 2020, Volume: 225, Issue:1

    Topics: Aging, Premature; Animals; CD4-Positive T-Lymphocytes; Cell Count; Cell Proliferation; Cells, Cultur

2020
Gallic acid regulates adipocyte hypertrophy and suppresses inflammatory gene expression induced by the paracrine interaction between adipocytes and macrophages in vitro and in vivo.
    Nutrition research (New York, N.Y.), 2020, Volume: 73

    Topics: Adipocytes; Animals; Disease Models, Animal; Gallic Acid; Gene Expression; Hypertrophy; Inflammation

2020
Anti-inflammatory effect of octyl gallate in alveolar macrophages cells and mice with acute lung injury.
    Journal of cellular physiology, 2020, Volume: 235, Issue:9

    Topics: Acute Lung Injury; Animals; Disease Models, Animal; Gallic Acid; Humans; Inflammation; Lung; Lung In

2020
3,4,5-Trihydroxybenzoic Acid Attenuates Ligature-Induced Periodontal Disease in Wistar Rats.
    Anti-inflammatory & anti-allergy agents in medicinal chemistry, 2021, Volume: 20, Issue:1

    Topics: Alveolar Bone Loss; Animals; Collagenases; Disease Models, Animal; Gallic Acid; Osteoblasts; Osteocl

2021
Gastroprotective effect of gallic acid against ethanol-induced gastric ulcer in rats: Involvement of the Nrf2/HO-1 signaling and anti-apoptosis role.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 126

    Topics: Animals; Anti-Ulcer Agents; Antioxidants; Apoptosis; Biopsy; Cytokines; Dinoprostone; Disease Models

2020
Chronic exposure of adult male Wistar rats to bisphenol A causes testicular oxidative stress: Role of gallic acid.
    Endocrine regulations, 2020, Jan-01, Volume: 54, Issue:1

    Topics: Animals; Antioxidants; Benzhydryl Compounds; Disease Models, Animal; Endocrine Disruptors; Gallic Ac

2020
Gallic acid is a dual α/β-secretase modulator that reverses cognitive impairment and remediates pathology in Alzheimer mice.
    The Journal of biological chemistry, 2020, 11-27, Volume: 295, Issue:48

    Topics: ADAM10 Protein; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secreta

2020
Tissue distribution and molecular docking research on the active components of Bidens bipinnata L. against hyperlipidemia.
    Biomedical chromatography : BMC, 2021, Volume: 35, Issue:4

    Topics: Animals; Bidens; Catechin; Chromatography, High Pressure Liquid; Disease Models, Animal; Drugs, Chin

2021
Leonurine Attenuates Myocardial Fibrosis Through Upregulation of miR-29a-3p in Mice Post-myocardial Infarction.
    Journal of cardiovascular pharmacology, 2021, 02-01, Volume: 77, Issue:2

    Topics: Angiotensin II; Animals; Cell Movement; Cell Proliferation; Cells, Cultured; Collagen; Disease Model

2021
Gallic Acid Alleviates Gouty Arthritis by Inhibiting NLRP3 Inflammasome Activation and Pyroptosis Through Enhancing Nrf2 Signaling.
    Frontiers in immunology, 2020, Volume: 11

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Gouty; Cells, Cultured; Disease Models, Animal; Gallic

2020
Gallic acid protects cerebral cortex, hippocampus, and striatum against oxidative damage and cholinergic dysfunction in an experimental model of manic-like behavior: Comparison with lithium effects.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2021, Volume: 81, Issue:2

    Topics: Animals; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Gallic Acid; Hippocampus; Lithium

2021
The benzoate plant metabolite ethyl gallate prevents cellular- and vascular-lipid accumulation in experimental models of atherosclerosis.
    Biochemical and biophysical research communications, 2021, 06-04, Volume: 556

    Topics: Animals; Apolipoproteins E; Atherosclerosis; ATP-Binding Cassette Transporters; Benzoates; Cholester

2021
Ferroptosis-related Genes for Overall Survival Prediction in Patients with Colorectal Cancer can be Inhibited by Gallic acid.
    International journal of biological sciences, 2021, Volume: 17, Issue:4

    Topics: Animals; Case-Control Studies; Colitis, Ulcerative; Colorectal Neoplasms; Disease Models, Animal; Dr

2021
Gallic acid anti-myotoxic activity and mechanism of action, a snake venom phospholipase A
    International journal of biological macromolecules, 2021, Aug-31, Volume: 185

    Topics: Anacardium; Animals; Disease Models, Animal; Gallic Acid; Gene Expression Regulation, Enzymologic; M

2021
Grape seed proanthocyanidin supplementation reduces adipocyte size and increases adipocyte number in obese rats.
    International journal of obesity (2005), 2017, Volume: 41, Issue:8

    Topics: Adipocytes; Adiposity; Animals; Antioxidants; Disease Models, Animal; Fatty Acid-Binding Proteins; G

2017
Combination therapy with octyl gallate and ferulic acid improves cognition and neurodegeneration in a transgenic mouse model of Alzheimer's disease.
    The Journal of biological chemistry, 2017, 07-07, Volume: 292, Issue:27

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Co

2017
The in vitro and in vivo protective effects of tannin derivatives against Salmonella enterica serovar Typhimurium infection.
    Microbial pathogenesis, 2017, Volume: 109

    Topics: Adhesins, Bacterial; Animals; Anti-Bacterial Agents; Bacterial Load; Cell Survival; Chemokine CCL2;

2017
Protective effect of gallic acid in experimental model of ketamine-induced psychosis: possible behaviour, biochemical, neurochemical and cellular alterations.
    Inflammopharmacology, 2018, Volume: 26, Issue:2

    Topics: Animals; Antioxidants; Behavior, Animal; Brain; Disease Models, Animal; Female; Gallic Acid; gamma-A

2018
Antiosteoporotic activity of a syringic acid diet in ovariectomized mice.
    Journal of natural medicines, 2017, Volume: 71, Issue:4

    Topics: Animals; Bone and Bones; Bone Density; Bone Resorption; Diet; Disease Models, Animal; Euterpe; Femal

2017
Ameliorative Effect of Gallic Acid in Doxorubicin-Induced Hepatotoxicity in Wistar Rats Through Antioxidant Defense System.
    Journal of dietary supplements, 2018, Mar-04, Volume: 15, Issue:2

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Bilirubin; Catalase; Chemical and

2018
Chemical composition and diuretic, natriuretic and kaliuretic effects of extracts of Mimosa bimucronata (DC.) Kuntze leaves and its majority constituent methyl gallate in rats.
    The Journal of pharmacy and pharmacology, 2017, Volume: 69, Issue:11

    Topics: Administration, Oral; Animals; Atropine; Cell Line; Disease Models, Animal; Diuretics; Gallic Acid;

2017
Antidepressant-like effect of gallic acid in mice: Dual involvement of serotonergic and catecholaminergic systems.
    Life sciences, 2017, Dec-01, Volume: 190

    Topics: Animals; Antidepressive Agents; Catecholamines; Depression; Disease Models, Animal; Dose-Response Re

2017
Leonurine Exerts Antidepressant-Like Effects in the Chronic Mild Stress-Induced Depression Model in Mice by Inhibiting Neuroinflammation.
    The international journal of neuropsychopharmacology, 2017, 11-01, Volume: 20, Issue:11

    Topics: Animals; Antidepressive Agents; Calcium-Binding Proteins; Cytokines; Depression; Disease Models, Ani

2017
Protective effects of gallic acid against methotrexate-induced toxicity in rats.
    Acta chirurgica Belgica, 2018, Volume: 118, Issue:3

    Topics: Alanine Transaminase; Analysis of Variance; Animals; Aspartate Aminotransferases; Biomarkers; Biopsy

2018
Gallic acid attenuates pulmonary fibrosis in a mouse model of transverse aortic contraction-induced heart failure.
    Vascular pharmacology, 2017, Volume: 99

    Topics: Animals; Aorta; Cadherins; Connective Tissue Growth Factor; Constriction; Disease Models, Animal; Ep

2017
Ulcer Prevention Effect Of 3,4,5-Tihydroxy-N0-[(2-Methyl-1H-Indol-3yl)Methylidene]Benzohydrazide In HCl/Ethanol-Induced Gastric Mucosal Damage In Rats.
    International journal of medical sciences, 2017, Volume: 14, Issue:13

    Topics: Animals; Antioxidants; bcl-2-Associated X Protein; Disease Models, Animal; Ethanol; Gallic Acid; Gas

2017
Gallic acid attenuates type I diabetic nephropathy in rats.
    Chemico-biological interactions, 2018, Feb-25, Volume: 282

    Topics: Animals; Antioxidants; Blood Urea Nitrogen; Creatinine; Diabetes Mellitus, Experimental; Diabetes Me

2018
Gallic Acid Alleviates Hypertriglyceridemia and Fat Accumulation via Modulating Glycolysis and Lipolysis Pathways in Perirenal Adipose Tissues of Rats Fed a High-Fructose Diet.
    International journal of molecular sciences, 2018, Jan-15, Volume: 19, Issue:1

    Topics: Adipose Tissue; Adiposity; Animals; Carbohydrate Metabolism; Diabetes Mellitus, Experimental; Diet,

2018
Phytochemical analysis and antibacterial activity of methanolic extract of Bergenia purpurascens against common respiratory infection causing bacterial species in vitro and in neonatal rats.
    Microbial pathogenesis, 2018, Volume: 117

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antioxidants; Bacteria; Benzopyrans; Catec

2018
Upregulating mTOR/ERK signaling with leonurine for promoting angiogenesis and tissue regeneration in a full-thickness cutaneous wound model.
    Food & function, 2018, Apr-25, Volume: 9, Issue:4

    Topics: Angiogenesis Inducing Agents; Animals; Cell Movement; Disease Models, Animal; Drugs, Chinese Herbal;

2018
Metagenomics Analysis of Gut Microbiota in a High Fat Diet-Induced Obesity Mouse Model Fed with (-)-Epigallocatechin 3-O-(3-O-Methyl) Gallate (EGCG3″Me).
    Molecular nutrition & food research, 2018, Volume: 62, Issue:13

    Topics: Animals; Diet, High-Fat; Disease Models, Animal; Gallic Acid; Gastrointestinal Microbiome; Male; Met

2018
Leonurine protects cardiac function following acute myocardial infarction through anti‑apoptosis by the PI3K/AKT/GSK3β signaling pathway.
    Molecular medicine reports, 2018, Volume: 18, Issue:2

    Topics: Administration, Oral; Animals; Apoptosis; bcl-2-Associated X Protein; Cardiotonic Agents; Cerebrovas

2018
Leonurine ameliorates the inflammatory responses in lipopolysaccharide-induced endometritis.
    International immunopharmacology, 2018, Volume: 61

    Topics: Animals; Anti-Inflammatory Agents; Cattle; Cells, Cultured; Disease Models, Animal; Endometritis; En

2018
Potential of the association of dodecyl gallate with nanostructured lipid system as a treatment for paracoccidioidomycosis: In vitro and in vivo efficacy and toxicity.
    International journal of pharmaceutics, 2018, Aug-25, Volume: 547, Issue:1-2

    Topics: Animals; Antifungal Agents; Biological Availability; Cell Line; Disease Models, Animal; Female; Fibr

2018
The antioxidant gallic acid induces anxiolytic-, but not antidepressant-like effect, in streptozotocin-induced diabetes.
    Metabolic brain disease, 2018, Volume: 33, Issue:5

    Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Antioxidants; Anxiety; Behavior, Animal; Depres

2018
Effect of wedelolactone and gallic acid on quinolinic acid-induced neurotoxicity and impaired motor function: significance to sporadic amyotrophic lateral sclerosis.
    Neurotoxicology, 2018, Volume: 68

    Topics: Amyotrophic Lateral Sclerosis; Animals; Antioxidants; Apoptosis; Brain; Coumarins; Disease Models, A

2018
A Novel Synthesized Sulfonamido-Based Gallate-JEZTC Blocks Cartilage Degradation on Rabbit Model of Osteoarthritis: An in Vitro and in Vivo Study.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 49, Issue:6

    Topics: Animals; Apoptosis; Benzamides; Cartilage, Articular; Chondrocytes; Disease Models, Animal; Down-Reg

2018
Leonurine inhibits IL-1β induced inflammation in murine chondrocytes and ameliorates murine osteoarthritis.
    International immunopharmacology, 2018, Volume: 65

    Topics: Animals; Chondrocytes; Disease Models, Animal; Gallic Acid; Gene Expression Regulation; Interleukin-

2018
Gallic acid activates hippocampal BDNF-Akt-mTOR signaling in chronic mild stress.
    Metabolic brain disease, 2019, Volume: 34, Issue:1

    Topics: Animals; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Gallic Acid; Hippocampus; Mice;

2019
Leonurine ameliorates adriamycin-induced podocyte injury via suppression of oxidative stress.
    Free radical research, 2018, Volume: 52, Issue:9

    Topics: Animals; Apoptosis; Disease Models, Animal; Doxorubicin; Gallic Acid; Humans; Kidney; Kidney Disease

2018
Effect of Syringic acid on antioxidant biomarkers and associated inflammatory markers in mice model of asthma.
    Drug development research, 2019, Volume: 80, Issue:2

    Topics: Animals; Anti-Asthmatic Agents; Antioxidants; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disea

2019
Gallic acid improved inflammation via NF-κB pathway in TNBS-induced ulcerative colitis.
    International immunopharmacology, 2019, Volume: 67

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Cell Line; Cell Proliferation; Colitis, Ulcerative; Cy

2019
Leonurine suppresses neuroinflammation through promoting oligodendrocyte maturation.
    Journal of cellular and molecular medicine, 2019, Volume: 23, Issue:2

    Topics: Animals; Cell Differentiation; Central Nervous System; Cuprizone; Disease Models, Animal; Encephalom

2019
Gallic and vanillic acid suppress inflammation and promote myelination in an in vitro mouse model of neurodegeneration.
    Molecular biology reports, 2019, Volume: 46, Issue:1

    Topics: Action Potentials; Animals; Demyelinating Diseases; Disease Models, Animal; Extracellular Matrix Pro

2019
In vivo fluid accumulation-inhibitory, anticolonization and anti-inflammatory and in vitro biofilm-inhibitory activities of methyl gallate isolated from Terminalia chebula against fluoroquinolones resistant Vibrio cholerae.
    Microbial pathogenesis, 2019, Volume: 128

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Biofilms; Cell Membrane; Cholera; Disease

2019
Protective effects of ethyl gallate and pentagalloylglucose, the active components of Qingwen Baidu Decoction, against lipopolysaccharide-induced acute lung injury in rats.
    Drug design, development and therapy, 2019, Volume: 13

    Topics: Acute Lung Injury; Animals; Capillary Permeability; Disease Models, Animal; Drugs, Chinese Herbal; G

2019
Gallic acid alleviates nasal inflammation via activation of Th1 and inhibition of Th2 and Th17 in a mouse model of allergic rhinitis.
    International immunopharmacology, 2019, Volume: 70

    Topics: Allergens; Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Eosinophils; Gallic

2019
A holistic view of gallic acid-induced attenuation in colitis based on microbiome-metabolomics analysis.
    Food & function, 2019, Jul-17, Volume: 10, Issue:7

    Topics: Amino Acids; Animals; Bacteria; Colitis, Ulcerative; Dextran Sulfate; Disease Models, Animal; Fatty

2019
The regulation effect of EGCG3''Me phospholipid complex on gut flora of a high-fat diet-induced obesity mouse model.
    Journal of food biochemistry, 2019, Volume: 43, Issue:7

    Topics: Animals; Bacteria; Camellia sinensis; Diet, High-Fat; Disease Models, Animal; Gallic Acid; Gastroint

2019
3,4,5-trihydroxycinnamic acid inhibits lipopolysaccharide (LPS)-induced inflammation by Nrf2 activation in vitro and improves survival of mice in LPS-induced endotoxemia model in vivo.
    Molecular and cellular biochemistry, 2014, Volume: 390, Issue:1-2

    Topics: Animals; Cell Line; Disease Models, Animal; Endotoxemia; Gallic Acid; Gene Expression Regulation; Hu

2014
Protective effects of gallic acid against chronic cerebral hypoperfusion-induced cognitive deficit and brain oxidative damage in rats.
    European journal of pharmacology, 2014, Jun-15, Volume: 733

    Topics: Animals; Antioxidants; Brain; Brain Ischemia; Chronic Disease; Cognition Disorders; Disease Models,

2014
Metabolomic signatures in peripheral blood associated with Alzheimer's disease amyloid-β-induced neuroinflammation.
    Journal of Alzheimer's disease : JAD, 2014, Volume: 42, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Biomarkers; Disease Models, Animal; Encephalitis;

2014
Synergistic effect of the combination of gallic acid and famotidine in protection of rat gastric mucosa.
    Pharmacological reports : PR, 2014, Volume: 66, Issue:4

    Topics: Animals; Anti-Ulcer Agents; Antioxidants; Disease Models, Animal; Drug Synergism; Drug Therapy, Comb

2014
Effect of trimethylgallic acid esters against chronic stress-induced anxiety-like behavior and oxidative stress in mice.
    Pharmacological reports : PR, 2014, Volume: 66, Issue:4

    Topics: Animals; Antioxidants; Anxiety; Behavior, Animal; Chronic Disease; Disease Models, Animal; Esters; G

2014
Effect of JEZTC, a synthetic compound, on proliferation and phenotype maintenance of rabbit articular chondrocytes in vitro.
    In vitro cellular & developmental biology. Animal, 2014, Volume: 50, Issue:10

    Topics: Animals; Antioxidants; Arthritis; Benzamides; Cartilage, Articular; Cell Proliferation; Chondrocytes

2014
The examination of protective effects of gallic acid against damage of oxidative stress during induced-experimental renal ischemia-reperfusion in experiment.
    Bratislavske lekarske listy, 2014, Volume: 115, Issue:9

    Topics: Animals; Disease Models, Animal; Gallic Acid; Kidney Diseases; Male; Oxidative Stress; Rats, Sprague

2014
Leonurine hydrochloride inhibits osteoclastogenesis and prevents osteoporosis associated with estrogen deficiency by inhibiting the NF-κB and PI3K/Akt signaling pathways.
    Bone, 2015, Volume: 75

    Topics: Animals; Blotting, Western; Cell Differentiation; Cells, Cultured; Disease Models, Animal; Electroph

2015
Leonurine ameliorates kidney fibrosis via suppressing TGF-β and NF-κB signaling pathway in UUO mice.
    International immunopharmacology, 2015, Volume: 25, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Epithelial-Mesenchymal Transit

2015
Gallic acid can play a chondroprotective role against AGE-induced osteoarthritis progression.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2015, Volume: 20, Issue:4

    Topics: Animals; Cartilage, Articular; Cells, Cultured; Chondrocytes; Disease Models, Animal; Disease Progre

2015
Gallic acid improved behavior, brain electrophysiology, and inflammation in a rat model of traumatic brain injury.
    Canadian journal of physiology and pharmacology, 2015, Volume: 93, Issue:8

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Behavior, Animal; Brain; Brain Injuries; Cy

2015
Protective Effects of Catechin against Monosodium Urate-Induced Inflammation through the Modulation of NLRP3 Inflammasome Activation.
    Journal of agricultural and food chemistry, 2015, Aug-26, Volume: 63, Issue:33

    Topics: Animals; Calcium; Carrier Proteins; Catechin; Disease Models, Animal; Free Radical Scavengers; Galli

2015
Gallic acid attenuates dextran sulfate sodium-induced experimental colitis in BALB/c mice.
    Drug design, development and therapy, 2015, Volume: 9

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Colitis; Colon; Cytoprotection; Dextran Sulfate; Di

2015
Gallic acid suppresses inflammation in dextran sodium sulfate-induced colitis in mice: Possible mechanisms.
    International immunopharmacology, 2015, Volume: 28, Issue:2

    Topics: Animals; Colitis; Cyclooxygenase 2; Cytokines; Dextran Sulfate; Disease Models, Animal; Gallic Acid;

2015
Gallic acid ameliorates renal functions by inhibiting the activation of p38 MAPK in experimentally induced type 2 diabetic rats and cultured rat proximal tubular epithelial cells.
    Chemico-biological interactions, 2015, Oct-05, Volume: 240

    Topics: Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephr

2015
Gallic acid-based indanone derivative interacts synergistically with tetracycline by inhibiting efflux pump in multidrug resistant E. coli.
    Applied microbiology and biotechnology, 2016, Volume: 100, Issue:5

    Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Disease Models, Animal; Drug Synergism; Drug-R

2016
Identification of gallic acid based glycoconjugates as a novel tubulin polymerization inhibitors.
    Organic & biomolecular chemistry, 2016, Jan-28, Volume: 14, Issue:4

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Proliferation; Disease Models, Animal; D

2016
Hepatoprotective effect of trimethylgallic acid esters against carbon tetrachloride-induced liver injury in rats.
    Indian journal of experimental biology, 2015, Volume: 53, Issue:12

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Carbon Tetrachloride; Chemical and Drug

2015
Mechanism(s) of action underlying the gastroprotective effect of ethyl acetate fraction obtained from the crude methanolic leaves extract of Muntingia calabura.
    BMC complementary and alternative medicine, 2016, Feb-24, Volume: 16

    Topics: Animals; Anti-Ulcer Agents; Antioxidants; Dinoprostone; Disease Models, Animal; Gallic Acid; Gastric

2016
Anti-Inflammatory Activities of Pentaherbs Formula, Berberine, Gallic Acid and Chlorogenic Acid in Atopic Dermatitis-Like Skin Inflammation.
    Molecules (Basel, Switzerland), 2016, Apr-20, Volume: 21, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Berberine; Cells, Cultured; Chemokines; Chlorogenic Acid; Cocultu

2016
Galla chinensis Compounds Remineralize Enamel Caries Lesions in a Rat Model.
    Caries research, 2016, Volume: 50, Issue:2

    Topics: Animals; Dental Caries; Dental Enamel; Diet, Cariogenic; Disease Models, Animal; Drugs, Chinese Herb

2016
Antiviral Effects of Black Raspberry (Rubus coreanus) Seed and Its Gallic Acid against Influenza Virus Infection.
    Viruses, 2016, 06-06, Volume: 8, Issue:6

    Topics: Animals; Antiviral Agents; Chromatography, Liquid; Disease Models, Animal; Gallic Acid; Influenza A

2016
Anti-ulcer mechanisms of polyphenols extract of Euphorbia umbellata (Pax) Bruyns (Euphorbiaceae).
    Journal of ethnopharmacology, 2016, Sep-15, Volume: 191

    Topics: Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; Antioxidants; Benzothiazoles; Chromatography, Hig

2016
Protective effect of Gallic acid on doxorubicin-induced testicular and epididymal toxicity.
    Andrologia, 2017, Volume: 49, Issue:4

    Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Apoptosis; Caspase 3; Disease Models, Animal; Do

2017
Investigation of synergistic mechanism and identification of interaction site of aldose reductase with the combination of gigantol and syringic acid for prevention of diabetic cataract.
    BMC complementary and alternative medicine, 2016, Aug-12, Volume: 16, Issue:1

    Topics: Aldehyde Reductase; Animals; Bibenzyls; Cataract; Cell Line; Cell Survival; Diabetes Complications;

2016
The Axon Protective Effects of Syringic Acid on Ischemia/Reperfusion Injury in a Rat Sciatic Nerve Model.
    Turkish neurosurgery, 2017, Volume: 27, Issue:1

    Topics: Animals; Apoptosis; Axons; Disease Models, Animal; Gallic Acid; Male; Neuroprotective Agents; Oxidat

2017
Gallic acid prevents isoproterenol-induced cardiac hypertrophy and fibrosis through regulation of JNK2 signaling and Smad3 binding activity.
    Scientific reports, 2016, 10-05, Volume: 6

    Topics: Animals; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Fibrosis; Gallic Acid; Gene Expressi

2016
Leonurine ameliorates cognitive dysfunction via antagonizing excitotoxic glutamate insults and inhibiting autophagy.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2016, Dec-01, Volume: 23, Issue:13

    Topics: Animals; Autophagy; Brain; Cognitive Dysfunction; Disease Models, Animal; Excitatory Postsynaptic Po

2016
Nutraceutical inherent of Spinacia oleracea Linn. methanolic leaf extract ameliorates isoproterenol induced myocardial necrosis in male albino Wistar rats via mitigating inflammation.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 85

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Cardiomyopathies; Chromatography, High Pressure Liquid

2017
Methyl Gallate Inhibits Osteoclast Formation and Function by Suppressing Akt and Btk-PLCγ2-Ca
    International journal of molecular sciences, 2017, Mar-07, Volume: 18, Issue:3

    Topics: Actins; Agammaglobulinaemia Tyrosine Kinase; Animals; Biomarkers; Bone Resorption; Calcium; Disease

2017
The modulatory effect of (-)-epigallocatechin 3-O-(3-O-methyl) gallate (EGCG3″Me) on intestinal microbiota of high fat diet-induced obesity mice model.
    Food research international (Ottawa, Ont.), 2017, Volume: 92

    Topics: Adult; Animals; Bacteroidetes; Diet, High-Fat; Disease Models, Animal; DNA, Bacterial; Feces; Female

2017
Comparison of hypolipidemic activity of synthetic gallic acid-linoleic acid ester with mixture of gallic acid and linoleic acid, gallic acid, and linoleic acid on high-fat diet induced obesity in C57BL/6 Cr Slc mice.
    Chemico-biological interactions, 2008, Jul-30, Volume: 174, Issue:2

    Topics: Adipocytes; Adipose Tissue; Animals; Body Weight; Cell Nucleus; Cholesterol, HDL; Cholesterol, LDL;

2008
Cardioprotective effect of gallic acid on cardiac troponin-T, cardiac marker enzymes, lipid peroxidation products and antioxidants in experimentally induced myocardial infarction in Wistar rats.
    Chemico-biological interactions, 2009, May-15, Volume: 179, Issue:2-3

    Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Biomarkers; Cardiotonic Ag

2009
Gallic acid prevents lysosomal damage in isoproterenol induced cardiotoxicity in Wistar rats.
    European journal of pharmacology, 2009, Aug-01, Volume: 615, Issue:1-3

    Topics: Acetylglucosaminidase; Adrenergic beta-Agonists; Animals; Antioxidants; beta-Galactosidase; Biomarke

2009
Antioxidant, antimutagenic, and antidiabetic activities of edible leaves from Cnidoscolus chayamansa Mc. Vaugh.
    Journal of food science, 2010, Volume: 75, Issue:2

    Topics: Animals; Antimutagenic Agents; Antioxidants; Catechin; Chromatography, High Pressure Liquid; Diabete

2010
Antiinflammatory and antioxidant activities of gum mastic.
    European review for medical and pharmacological sciences, 2010, Volume: 14, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biphenyl Compounds; Carrageenan; Chromatography, Hi

2010
Neuroprotective effects of leonurine on ischemia/reperfusion-induced mitochondrial dysfunctions in rat cerebral cortex.
    Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:12

    Topics: Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Brain Ischemia; Cer

2010
Locomotor damage and brain oxidative stress induced by lead exposure are attenuated by gallic acid treatment.
    Toxicology letters, 2011, May-30, Volume: 203, Issue:1

    Topics: Animals; Antioxidants; Behavior, Animal; Brain; Catalase; Chelating Agents; Disease Models, Animal;

2011
Benefits of ethyl gallate versus norepinephrine in the treatment of cardiovascular collapse in Pseudomonas aeruginosa septic shock in dogs.
    Critical care medicine, 2012, Volume: 40, Issue:2

    Topics: Analysis of Variance; Animals; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drug

2012
Anti-inflammatory activity of Pistacia khinjuk in different experimental models: isolation and characterization of its flavonoids and galloylated sugars.
    Journal of medicinal food, 2012, Volume: 15, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Disease Models, Animal; Drug Discove

2012
Ferulic acid is nephrodamaging while gallic acid is renal protective in long term treatment of chronic kidney disease.
    Clinical nutrition (Edinburgh, Scotland), 2012, Volume: 31, Issue:3

    Topics: Animals; Antioxidants; Collagen; Coumaric Acids; Dietary Supplements; Disease Models, Animal; Fibros

2012
Motor disorders and impaired electrical power of pallidal EEG improved by gallic acid in animal model of Parkinson's disease.
    Pakistan journal of biological sciences : PJBS, 2011, Dec-15, Volume: 14, Issue:24

    Topics: Adrenergic Agents; Animals; Antioxidants; Disease Models, Animal; Electroencephalography; Gallic Aci

2011
Leonurine protects brain injury by increased activities of UCP4, SOD, CAT and Bcl-2, decreased levels of MDA and Bax, and ameliorated ultrastructure of mitochondria in experimental stroke.
    Brain research, 2012, Sep-20, Volume: 1474

    Topics: Animals; bcl-2-Associated X Protein; Blotting, Western; Brain Injuries; Catalase; Disease Models, An

2012
Syringic acid ameliorates (L)-NAME-induced hypertension by reducing oxidative stress.
    Naunyn-Schmiedeberg's archives of pharmacology, 2012, Volume: 385, Issue:12

    Topics: Animals; Antioxidants; Biomarkers; Blood Pressure; Disease Models, Animal; Dose-Response Relationshi

2012
Gallic acid decreases vacuous chewing movements induced by reserpine in rats.
    Pharmacology, biochemistry, and behavior, 2013, Volume: 104

    Topics: Adrenergic Uptake Inhibitors; Animals; Antioxidants; Antipsychotic Agents; Brain; Disease Models, An

2013
Glutathione ester but not glutathione protects against cisplatin-induced ototoxicity in a rat model.
    Journal of the American Academy of Audiology, 2003, Volume: 14, Issue:3

    Topics: Acoustic Stimulation; Animals; Antineoplastic Agents; Cisplatin; Disease Models, Animal; Evoked Pote

2003
Novel mechanism of enhanced nociception in a model of AIDS therapy-induced painful peripheral neuropathy in the rat.
    Pain, 2004, Volume: 107, Issue:1-2

    Topics: Aminoquinolines; Animals; Anti-HIV Agents; Antineoplastic Agents; Behavior, Animal; Calcium Channel

2004
In vivo treatment of acute Chlamydia pneumoniae infection with the flavonoids quercetin and luteolin and an alkyl gallate, octyl gallate, in a mouse model.
    Biochemical pharmacology, 2005, Oct-15, Volume: 70, Issue:8

    Topics: Animals; Base Sequence; Chlamydia Infections; Chlamydophila pneumoniae; Disease Models, Animal; DNA

2005
Anti-diarrheal effect of Galla Chinensis on the Escherichia coli heat-labile enterotoxin and ganglioside interaction.
    Journal of ethnopharmacology, 2006, Feb-20, Volume: 103, Issue:3

    Topics: Animals; Antidiarrheals; Bacterial Toxins; Binding, Competitive; Diarrhea; Disease Models, Animal; D

2006
Blockade of intracellular calcium release induces an antidepressant-like effect in the mouse forced swimming test.
    Neuropharmacology, 2006, Volume: 50, Issue:3

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Calcium; Calcium Channel Blo

2006
The anti-anaphylactic effect of the gall of Rhus javanica is mediated through inhibition of histamine release and inflammatory cytokine secretion.
    International immunopharmacology, 2005, Volume: 5, Issue:13-14

    Topics: Anaphylaxis; Animals; Anti-Allergic Agents; Calcium; Cell Line; Cyclic AMP; Cytokines; Disease Model

2005
Gastroprotective effect of standardized extract of Ficus glomerata fruit on experimental gastric ulcers in rats.
    Journal of ethnopharmacology, 2008, Jan-17, Volume: 115, Issue:2

    Topics: Animals; Anti-Ulcer Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Ellagic Acid;

2008
Prevention and reduction of neural damage in ischemic strokes by w-(N,N'-diethylamino)-n-alkyl-3,4,5-trimethoxybenzoate compounds.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 275, Issue:1

    Topics: Animals; Aorta; Brain Ischemia; Calcium; Calcium Channel Blockers; Cells, Cultured; Cerebral Cortex;

1995
Differential acetylcholine release mechanisms in the ischemic and non-ischemic myocardium.
    Journal of molecular and cellular cardiology, 2000, Volume: 32, Issue:3

    Topics: Acetylcholine; Animals; Arterial Occlusive Diseases; Calcium Channel Blockers; Cats; Disease Models,

2000
[Effects of psidium components on cytokine productions in helper T cells and type-I allergy].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2000, Volume: 120, Issue:4

    Topics: Animals; Anti-Allergic Agents; Antibody Formation; Cells, Cultured; Cytokines; Depression, Chemical;

2000
Either desipramine or TMB-8 suppresses cyanide-induced norepinephrine efflux from in vivo cardiac sympathetic nerves of cats.
    Brain research, 2000, May-02, Volume: 864, Issue:1

    Topics: Animals; Antidepressive Agents, Tricyclic; Calcium Channel Blockers; Cats; Cyanides; Desipramine; Di

2000
Propyl gallate-contact sensitization and orally-induced tolerance.
    Archives of dermatology, 1974, Volume: 109, Issue:4

    Topics: 1-Propanol; Administration, Oral; Administration, Topical; Animals; Antioxidants; Chlorobenzenes; De

1974