gallic acid has been researched along with Diabetes Mellitus, Type 2 in 20 studies
gallate : A trihydroxybenzoate that is the conjugate base of gallic acid.
Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Syringic acid (SA) is a phenolic compound present in the fruit of the assai palm, Euterpe oleracea, and in the mycelium of the shiitake mushroom, Lentinula edodes." | 5.62 | Dietary syringic acid reduces fat mass in an ovariectomy-induced mouse model of obesity. ( Homma, Y; Iwamoto, K; Kawaguchi, N; Moriyama, T; Shirasaka, N; Suzuki, T; Tanaka, T; Wada, M; Yano, E, 2021) |
| "After induction of type 2 diabetes, diabetic rats were orally treated with 20 mg/kg body mass gallic acid and 40 mg/kg body mass p-coumaric acid for six weeks." | 5.48 | Modulation of hyperglycemia and dyslipidemia in experimental type 2 diabetes by gallic acid and p-coumaric acid: The role of adipocytokines and PPARγ. ( Abdel-Moneim, A; Ashour, MB; El-Twab, SMA; Reheim, ESA; Yousef, AI, 2018) |
| " This study aimed at investigating the effect of hamamelitannin on glycogen synthesis in an insulin resistance model using L6 myotubes." | 3.96 | Molecular process of glucose uptake and glycogen storage due to hamamelitannin via insulin signalling cascade in glucose metabolism. ( Al-Dhabi, NA; Arasu, MV; Arockiaraj, J; Arshad, A; Chandrakumar, SS; Guru, A; Issac, PK; Lite, C; Saraswathi, NT, 2020) |
| "Oxidative imbalance plays a key role in cancer induction and cardiovascular diseases (CVD) in patients with type 2 diabetes mellitus (T2DM)." | 2.87 | Gallic Acid Improves Health-Associated Biochemical Parameters and Prevents Oxidative Damage of DNA in Type 2 Diabetes Patients: Results of a Placebo-Controlled Pilot Study. ( Al-Serori, H; Brath, H; Ferk, F; Knasmueller, S; Kundi, M; Marculescu, R; Mišík, M; Saiko, P; Szekeres, T; Wagner, KH, 2018) |
| "Gallic acid is a type of phenolic acid that has been shown to be a potential drug candidate to treat diabetic kidney disease, an important complication of diabetes." | 1.91 | Gallic acid improves the metformin effects on diabetic kidney disease in mice. ( Hong, Y; Sun, W; Wang, J; Xu, X; Zhang, K; Zhang, L, 2023) |
| "Obesity is currently the most common cause of metabolic diseases including type 2 diabetes and hyperlipidemia." | 1.72 | Inhibitory Effects of Hydrolysable Tannins on Lipid Accumulation in 3T3-L1 Cells. ( Kaneko, H; Kishikawa, Y; Koike, Y; Nobushi, Y; Shimba, S; Uchiyama, T; Wada, T, 2022) |
| "Syringic acid (SA) is a phenolic compound present in the fruit of the assai palm, Euterpe oleracea, and in the mycelium of the shiitake mushroom, Lentinula edodes." | 1.62 | Dietary syringic acid reduces fat mass in an ovariectomy-induced mouse model of obesity. ( Homma, Y; Iwamoto, K; Kawaguchi, N; Moriyama, T; Shirasaka, N; Suzuki, T; Tanaka, T; Wada, M; Yano, E, 2021) |
| "Gallic acid is a phenolic compound with biological and pharmacological activities." | 1.62 | Hepatoprotective effect of gallic acid against type 2-induced diabetic liver injury in male rats through modulation of fetuin-A and GLP-1 with involvement of ERK1/2/NF-κB and Wnt1/β-catenin signaling pathways. ( Abd-Elmoniem, HA; Bashar, SM; Elhadidy, MG; Hamed, B; Helmy, S; Mostafa, AF, 2021) |
| "After induction of type 2 diabetes, diabetic rats were orally treated with 20 mg/kg body mass gallic acid and 40 mg/kg body mass p-coumaric acid for six weeks." | 1.48 | Modulation of hyperglycemia and dyslipidemia in experimental type 2 diabetes by gallic acid and p-coumaric acid: The role of adipocytokines and PPARγ. ( Abdel-Moneim, A; Ashour, MB; El-Twab, SMA; Reheim, ESA; Yousef, AI, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (5.00) | 29.6817 |
| 2010's | 10 (50.00) | 24.3611 |
| 2020's | 9 (45.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, N | 1 |
| Wang, LJ | 1 |
| Jiang, B | 1 |
| Li, XQ | 1 |
| Guo, CL | 1 |
| Guo, SJ | 1 |
| Shi, DY | 1 |
| Oulous, A | 1 |
| Daoudi, NE | 1 |
| Harit, T | 1 |
| Cherfi, M | 1 |
| Bnouham, M | 1 |
| Malek, F | 1 |
| Tanaka, T | 2 |
| Iwamoto, K | 1 |
| Wada, M | 1 |
| Yano, E | 1 |
| Suzuki, T | 1 |
| Kawaguchi, N | 1 |
| Shirasaka, N | 1 |
| Moriyama, T | 1 |
| Homma, Y | 1 |
| Xu, Y | 2 |
| Tang, G | 1 |
| Zhang, C | 2 |
| Wang, N | 1 |
| Feng, Y | 1 |
| Ahn, D | 1 |
| Kim, J | 1 |
| Nam, G | 1 |
| Zhao, X | 1 |
| Kwon, J | 1 |
| Hwang, JY | 1 |
| Kim, JK | 1 |
| Yoon, SY | 1 |
| Chung, SJ | 1 |
| Nobushi, Y | 1 |
| Wada, T | 1 |
| Koike, Y | 1 |
| Kaneko, H | 1 |
| Shimba, S | 1 |
| Uchiyama, T | 1 |
| Kishikawa, Y | 1 |
| Hong, Y | 1 |
| Wang, J | 1 |
| Sun, W | 1 |
| Zhang, L | 1 |
| Xu, X | 1 |
| Zhang, K | 1 |
| Issac, PK | 1 |
| Guru, A | 1 |
| Chandrakumar, SS | 1 |
| Lite, C | 1 |
| Saraswathi, NT | 1 |
| Arasu, MV | 1 |
| Al-Dhabi, NA | 2 |
| Arshad, A | 1 |
| Arockiaraj, J | 1 |
| Frediansyah, A | 1 |
| Romadhoni, F | 1 |
| Nurhayati, R | 1 |
| Wibowo, AT | 1 |
| Bashar, SM | 1 |
| Elhadidy, MG | 1 |
| Mostafa, AF | 1 |
| Hamed, B | 1 |
| Helmy, S | 1 |
| Abd-Elmoniem, HA | 1 |
| Abdel-Moneim, A | 2 |
| Yousef, AI | 2 |
| Abd El-Twab, SM | 1 |
| Abdel Reheim, ES | 1 |
| Ashour, MB | 2 |
| Ferk, F | 1 |
| Kundi, M | 1 |
| Brath, H | 1 |
| Szekeres, T | 1 |
| Al-Serori, H | 1 |
| Mišík, M | 1 |
| Saiko, P | 1 |
| Marculescu, R | 1 |
| Wagner, KH | 1 |
| Knasmueller, S | 1 |
| El-Twab, SMA | 1 |
| Reheim, ESA | 1 |
| Miyata, Y | 1 |
| Tamaru, S | 1 |
| Tamaya, K | 1 |
| Matsui, T | 1 |
| Nagata, Y | 1 |
| Tanaka, K | 1 |
| Gandhi, GR | 1 |
| Jothi, G | 1 |
| Antony, PJ | 1 |
| Balakrishna, K | 1 |
| Paulraj, MG | 1 |
| Ignacimuthu, S | 1 |
| Stalin, A | 1 |
| Ahad, A | 1 |
| Ahsan, H | 1 |
| Mujeeb, M | 1 |
| Siddiqui, WA | 1 |
| Huang, DW | 1 |
| Chang, WC | 1 |
| Wu, JS | 1 |
| Shih, RW | 1 |
| Shen, SC | 1 |
| Kusirisin, W | 1 |
| Srichairatanakool, S | 1 |
| Lerttrakarnnon, P | 1 |
| Lailerd, N | 1 |
| Suttajit, M | 1 |
| Jaikang, C | 1 |
| Chaiyasut, C | 1 |
| Huang, H | 1 |
| Xin, H | 1 |
| Liu, X | 1 |
| Wen, D | 1 |
| Zhang, Y | 1 |
| Zhu, YZ | 1 |
| Xiao, J | 1 |
| Zhao, Y | 1 |
| Wang, H | 1 |
| Yuan, Y | 1 |
| Yang, F | 1 |
| Kai, G | 1 |
2 reviews available for gallic acid and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Recent progress of the development of dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV I | 2018 |
Gallic Acid and Diabetes Mellitus: Its Association with Oxidative Stress.
Topics: Antioxidants; Diabetes Mellitus, Type 2; Gallic Acid; Humans; Hyperglycemia; Hypoglycemic Agents; In | 2021 |
1 trial available for gallic acid and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Gallic Acid Improves Health-Associated Biochemical Parameters and Prevents Oxidative Damage of DNA in Type 2 Diabetes Patients: Results of a Placebo-Controlled Pilot Study.
Topics: Aged; C-Reactive Protein; Cardiovascular Diseases; Cross-Over Studies; Diabetes Mellitus, Type 2; DN | 2018 |
17 other studies available for gallic acid and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
New pyrazole-tetrazole hybrid compounds as potent α-amylase and non-enzymatic glycation inhibitors.
Topics: alpha-Amylases; Diabetes Mellitus, Type 2; Humans; Pyrazoles; Pyridines; Tetrazoles | 2022 |
Dietary syringic acid reduces fat mass in an ovariectomy-induced mouse model of obesity.
Topics: Animals; Body Weight; Diabetes Mellitus, Type 2; Diet, High-Fat; Female; Gallic Acid; Humans; Mice; | 2021 |
Ethyl Gallate Dual-Targeting PTPN6 and PPARγ Shows Anti-Diabetic and Anti-Obese Effects.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; AMP-Activated Protein Kinases; Animals; Diabetes Mellitus, T | 2022 |
Inhibitory Effects of Hydrolysable Tannins on Lipid Accumulation in 3T3-L1 Cells.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; CCAAT-Enhancer-Binding Protein-alpha; Cell Differen | 2022 |
Gallic acid improves the metformin effects on diabetic kidney disease in mice.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Gallic | 2023 |
Molecular process of glucose uptake and glycogen storage due to hamamelitannin via insulin signalling cascade in glucose metabolism.
Topics: Animals; Biological Transport; Carbohydrate Metabolism; Cell Survival; Diabetes Mellitus, Type 2; Ga | 2020 |
Fermentation of Jamaican Cherries Juice Using
Topics: Antioxidants; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Fermentation; Flavonoids; Fruit; Fruit a | 2021 |
Hepatoprotective effect of gallic acid against type 2-induced diabetic liver injury in male rats through modulation of fetuin-A and GLP-1 with involvement of ERK1/2/NF-κB and Wnt1/β-catenin signaling pathways.
Topics: alpha-2-HS-Glycoprotein; Animals; beta Catenin; Diabetes Mellitus, Experimental; Diabetes Mellitus, | 2021 |
Gallic acid and p-coumaric acid attenuate type 2 diabetes-induced neurodegeneration in rats.
Topics: Animals; Antioxidants; Coumaric Acids; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; G | 2017 |
Modulation of hyperglycemia and dyslipidemia in experimental type 2 diabetes by gallic acid and p-coumaric acid: The role of adipocytokines and PPARγ.
Topics: Adipokines; Animals; Coumaric Acids; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dru | 2018 |
Theflavins and theasinensin A derived from fermented tea have antihyperglycemic and hypotriacylglycerolemic effects in KK-A(y) mice and Sprague-Dawley rats.
Topics: Animals; Benzopyrans; Biflavonoids; Camellia sinensis; Catechin; Diabetes Mellitus, Type 2; Dietary | 2013 |
Gallic acid attenuates high-fat diet fed-streptozotocin-induced insulin resistance via partial agonism of PPARγ in experimental type 2 diabetic rats and enhances glucose uptake through translocation and activation of GLUT4 in PI3K/p-Akt signaling pathway.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Gallic Acid; Ge | 2014 |
Gallic acid ameliorates renal functions by inhibiting the activation of p38 MAPK in experimentally induced type 2 diabetic rats and cultured rat proximal tubular epithelial cells.
Topics: Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephr | 2015 |
Gallic acid ameliorates hyperglycemia and improves hepatic carbohydrate metabolism in rats fed a high-fructose diet.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; C-Peptide; Carbohydrate Metabolism; | 2016 |
Antioxidative activity, polyphenolic content and anti-glycation effect of some Thai medicinal plants traditionally used in diabetic patients.
Topics: Antioxidants; Benzothiazoles; Caffeic Acids; Catechin; Diabetes Mellitus, Type 2; Flavonoids; Free R | 2009 |
Novel anti-diabetic effect of SCM-198 via inhibiting the hepatic NF-κB pathway in db/db mice.
Topics: Adipose Tissue, White; Animals; Anti-Inflammatory Agents; Blood Glucose; Body Weight; Diabetes Melli | 2012 |
Non-covalent interaction of dietary polyphenols with total plasma proteins of type II diabetes: molecular structure/property-affinity relationships.
Topics: Binding Sites; Blood Proteins; Catechin; Diabetes Mellitus, Type 2; Flavanones; Flavones; Flavonols; | 2011 |