Page last updated: 2024-10-17

gallic acid and Cirrhosis, Liver

gallic acid has been researched along with Cirrhosis, Liver in 6 studies

gallate : A trihydroxybenzoate that is the conjugate base of gallic acid.

Research Excerpts

ExcerptRelevanceReference
"These results provide evidence for the first time that GA causes selective HSC death through a Ca(2+)/calpain I-mediated necrosis cascade, suggesting that GA may represent a potential therapeutic agent to combat liver fibrosis."7.80Gallic acid selectively induces the necrosis of activated hepatic stellate cells via a calcium-dependent calpain I activation pathway. ( Hsieh, SC; Hsu, SL; Hsueh, CM; Liu, MC; Wu, CC; Wu, CH; Yen, JH, 2014)
"These results provide evidence for the first time that GA causes selective HSC death through a Ca(2+)/calpain I-mediated necrosis cascade, suggesting that GA may represent a potential therapeutic agent to combat liver fibrosis."3.80Gallic acid selectively induces the necrosis of activated hepatic stellate cells via a calcium-dependent calpain I activation pathway. ( Hsieh, SC; Hsu, SL; Hsueh, CM; Liu, MC; Wu, CC; Wu, CH; Yen, JH, 2014)
"Gallic acid (GA) is a polyphenolic compound with proven efficacy against hepatic fibrosis in experimental animals."1.56Impact of Reverse Micelle Loaded Lipid Nanocapsules on the Delivery of Gallic Acid into Activated Hepatic Stellate Cells: A Promising Therapeutic Approach for Hepatic Fibrosis. ( El-Maadawy, WH; ElMeshad, AN; Radwan, SAA; Shoukri, RA; Yousry, C, 2020)
"Dimethylnitrosamine (DMN) is a potent hepatotoxin, carcinogen, and mutagen."1.48Gallic Acid Attenuates Dimethylnitrosamine-Induced Liver Fibrosis by Alteration of Smad Phosphoisoform Signaling in Rats. ( Chen, Y; Mo, Q; Wang, Y; Zhou, G; Zhou, Z, 2018)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (66.67)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Hussein, RM1
Anwar, MM1
Farghaly, HS1
Kandeil, MA1
Radwan, SAA1
El-Maadawy, WH1
ElMeshad, AN1
Shoukri, RA1
Yousry, C1
Chen, Y1
Zhou, Z1
Mo, Q1
Zhou, G1
Wang, Y1
Wang, J1
Tang, L1
White, J1
Fang, J1
Hsieh, SC1
Wu, CH1
Wu, CC1
Yen, JH1
Liu, MC1
Hsueh, CM1
Hsu, SL1
Itoh, A1
Isoda, K1
Kondoh, M1
Kawase, M1
Watari, A1
Kobayashi, M1
Tamesada, M1
Yagi, K1

Other Studies

6 other studies available for gallic acid and Cirrhosis, Liver

ArticleYear
Gallic acid and ferulic acid protect the liver from thioacetamide-induced fibrosis in rats via differential expression of miR-21, miR-30 and miR-200 and impact on TGF-β1/Smad3 signaling.
    Chemico-biological interactions, 2020, Jun-01, Volume: 324

    Topics: Animals; Coumaric Acids; Down-Regulation; Gallic Acid; Gene Expression; Liver; Liver Cirrhosis; Male

2020
Impact of Reverse Micelle Loaded Lipid Nanocapsules on the Delivery of Gallic Acid into Activated Hepatic Stellate Cells: A Promising Therapeutic Approach for Hepatic Fibrosis.
    Pharmaceutical research, 2020, Sep-01, Volume: 37, Issue:9

    Topics: Animals; Cell Line, Transformed; Cell Movement; Cells, Cultured; Drug Delivery Systems; Gallic Acid;

2020
Gallic Acid Attenuates Dimethylnitrosamine-Induced Liver Fibrosis by Alteration of Smad Phosphoisoform Signaling in Rats.
    BioMed research international, 2018, Volume: 2018

    Topics: Animals; Dimethylnitrosamine; Gallic Acid; Liver Cirrhosis; Male; Phosphoproteins; Protein Isoforms;

2018
Inhibitory effect of gallic acid on CCl4-mediated liver fibrosis in mice.
    Cell biochemistry and biophysics, 2014, Volume: 69, Issue:1

    Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Carbon Tetrachloride; Coll

2014
Gallic acid selectively induces the necrosis of activated hepatic stellate cells via a calcium-dependent calpain I activation pathway.
    Life sciences, 2014, Apr-25, Volume: 102, Issue:1

    Topics: Animals; Antioxidants; Calcium; Calpain; Dose-Response Relationship, Drug; Gallic Acid; Hepatic Stel

2014
Hepatoprotective effect of syringic acid and vanillic acid on CCl4-induced liver injury.
    Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:6

    Topics: Animals; Biological Products; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury

2010