gallic acid has been researched along with Carcinoma, Hepatocellular in 15 studies
gallate : A trihydroxybenzoate that is the conjugate base of gallic acid.
Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Thus, in order to better comprehend the mechanism by which polyphenols regulate hTERT, the present study investigated the effects of the natural polyphenols Resveratrol, Gallic acid, and Kuromanin chloride on hTERT, Nrf2, and SIRT1 expression as well as oxidative stress in HepG2 hepatocellular carcinoma." | 8.31 | The effect of natural polyphenols Resveratrol, Gallic acid, and Kuromanin chloride on human telomerase reverse transcriptase (hTERT) expression in HepG2 hepatocellular carcinoma: role of SIRT1/Nrf2 signaling pathway and oxidative stress. ( Azadbakht, O; Behrouj, H; Ghojoghi, R; Moghadam, D; Sabaghan, M; Vakili, S; Veisi, A; Zarei, R; Zarezade, V, 2023) |
| " In the present study, we investigated the antiproliferative effect of gallic acid during diethylnitrosamine (DEN)-induced hepatocellular carcinoma (HCC) in male wistar albino rats." | 7.74 | Antiproliferative potential of gallic acid against diethylnitrosamine-induced rat hepatocellular carcinoma. ( Anandakumar, P; Devaki, T; Jagan, S; Kamaraj, S; Ramakrishnan, G, 2008) |
| "Nonalcoholic fatty liver disease (NAFLD) usually includes NAFL called simple hepatosteatosis and nonalcoholic steatohepatitis (NASH) called more steatohepatitis." | 5.91 | Phytochemical gallic acid alleviates nonalcoholic fatty liver disease via AMPK-ACC-PPARa axis through dual regulation of lipid metabolism and mitochondrial function. ( Liu, Z; Wang, E; Wang, J; Yang, L; Zhang, J; Zhang, W; Zhao, W, 2023) |
| "The global burden of hepatocellular carcinoma is increasing; actually, it is estimated as 750,000 new cases annually." | 5.46 | Gallic acid against hepatocellular carcinoma: An integrated scheme of the potential mechanisms of action from in vivo study. ( Aglan, HA; Ahmed, HH; El-Toumy, SA; Mahmoud, NS, 2017) |
| " Thus, in order to better comprehend the mechanism by which polyphenols regulate hTERT, the present study investigated the effects of the natural polyphenols Resveratrol, Gallic acid, and Kuromanin chloride on hTERT, Nrf2, and SIRT1 expression as well as oxidative stress in HepG2 hepatocellular carcinoma." | 4.31 | The effect of natural polyphenols Resveratrol, Gallic acid, and Kuromanin chloride on human telomerase reverse transcriptase (hTERT) expression in HepG2 hepatocellular carcinoma: role of SIRT1/Nrf2 signaling pathway and oxidative stress. ( Azadbakht, O; Behrouj, H; Ghojoghi, R; Moghadam, D; Sabaghan, M; Vakili, S; Veisi, A; Zarei, R; Zarezade, V, 2023) |
| "encapsulated GA-NC (gallic acid nanocomposite) in normal and hepatocellular carcinoma (HCC)-induced rats." | 3.88 | Improving Anti-Cancer Potentiality and Bioavailability of Gallic Acid by Designing Polymeric Nanocomposite Formulation ( Abd-Rabou, AA; Ahmed, HH; Galal, AF; Mehaya, FM; Shalby, AB, 2018) |
| " In the present study, we investigated the antiproliferative effect of gallic acid during diethylnitrosamine (DEN)-induced hepatocellular carcinoma (HCC) in male wistar albino rats." | 3.74 | Antiproliferative potential of gallic acid against diethylnitrosamine-induced rat hepatocellular carcinoma. ( Anandakumar, P; Devaki, T; Jagan, S; Kamaraj, S; Ramakrishnan, G, 2008) |
| "Nonalcoholic fatty liver disease (NAFLD) usually includes NAFL called simple hepatosteatosis and nonalcoholic steatohepatitis (NASH) called more steatohepatitis." | 1.91 | Phytochemical gallic acid alleviates nonalcoholic fatty liver disease via AMPK-ACC-PPARa axis through dual regulation of lipid metabolism and mitochondrial function. ( Liu, Z; Wang, E; Wang, J; Yang, L; Zhang, J; Zhang, W; Zhao, W, 2023) |
| "The global burden of hepatocellular carcinoma is increasing; actually, it is estimated as 750,000 new cases annually." | 1.46 | Gallic acid against hepatocellular carcinoma: An integrated scheme of the potential mechanisms of action from in vivo study. ( Aglan, HA; Ahmed, HH; El-Toumy, SA; Mahmoud, NS, 2017) |
| "Gallic acid was identified and quantified in EP extract and active fractions, EP." | 1.43 | Pro-apoptotic and cytotoxic effects of enriched fraction of Elytranthe parasitica (L.) Danser against HepG2 Hepatocellular carcinoma. ( Aranjani, JM; Biswas, S; Kumar, N; Lobo, R; Mathew, AE; Mathew, JE; Nandakumar, K; Varghese, S, 2016) |
| "The mechanism of human hepatoma BEL-7404 cells apoptosis induced by Galic acid from leaves of Phyllanthus emblica may be blocking G2/M period in cell life cycle, up-regulating the expression of Bax and down-regulating the expression of Bcl-2, that can decrease membrane potential of mitochondria,and triggered the caspases of activation of cascade and induced cell death." | 1.37 | [Study of galic acid extracted from the leaves of Phyllanthus emblica on apoptotic mechanism of human hepatocellular carcinoma cells BEL-7404]. ( Huang, JL; Zhong, ZG, 2011) |
| "In the present study, the human hepatoma cell line, HepG2, was used as a model to investigate the effect of antioxidant phenolic acids on enzymatic activity and expression of one of the major phase II sulfate conjugation enzymes, P-form phenolsulfotransferase (PST-P)." | 1.33 | Induction of phenolsulfotransferase expression by phenolic acids in human hepatoma HepG2 cells. ( Huang, SM; Yeh, CT; Yen, GC, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.67) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 5 (33.33) | 29.6817 |
| 2010's | 4 (26.67) | 24.3611 |
| 2020's | 4 (26.67) | 2.80 |
| Authors | Studies |
|---|---|
| Jurič, A | 1 |
| Huđek Turković, A | 1 |
| Brčić Karačonji, I | 1 |
| Prđun, S | 1 |
| Bubalo, D | 1 |
| Durgo, K | 1 |
| Moghadam, D | 1 |
| Zarei, R | 1 |
| Vakili, S | 1 |
| Ghojoghi, R | 1 |
| Zarezade, V | 1 |
| Veisi, A | 1 |
| Sabaghan, M | 1 |
| Azadbakht, O | 1 |
| Behrouj, H | 1 |
| Zhang, J | 1 |
| Zhang, W | 1 |
| Yang, L | 1 |
| Zhao, W | 1 |
| Liu, Z | 1 |
| Wang, E | 1 |
| Wang, J | 1 |
| Huang, CY | 1 |
| Chang, YJ | 1 |
| Wei, PL | 1 |
| Hung, CS | 1 |
| Wang, W | 1 |
| Aglan, HA | 1 |
| Ahmed, HH | 2 |
| El-Toumy, SA | 1 |
| Mahmoud, NS | 1 |
| Galal, AF | 1 |
| Shalby, AB | 1 |
| Abd-Rabou, AA | 1 |
| Mehaya, FM | 1 |
| Kumar, N | 1 |
| Biswas, S | 1 |
| Mathew, AE | 1 |
| Varghese, S | 1 |
| Mathew, JE | 1 |
| Nandakumar, K | 1 |
| Aranjani, JM | 1 |
| Lobo, R | 1 |
| Jagan, S | 1 |
| Ramakrishnan, G | 1 |
| Anandakumar, P | 1 |
| Kamaraj, S | 1 |
| Devaki, T | 1 |
| Zhong, ZG | 2 |
| Huang, JL | 2 |
| Liang, H | 1 |
| Zhong, YN | 1 |
| Zhang, WY | 1 |
| Wu, DP | 1 |
| Zeng, CL | 1 |
| Wang, JS | 1 |
| Wei, YH | 1 |
| Dauer, A | 1 |
| Hensel, A | 1 |
| Lhoste, E | 1 |
| Knasmüller, S | 1 |
| Mersch-Sundermann, V | 1 |
| Yeh, CT | 1 |
| Huang, SM | 1 |
| Yen, GC | 1 |
| Banfi, C | 1 |
| Mussoni, L | 1 |
| Risé, P | 1 |
| Cattaneo, MG | 1 |
| Vicentini, L | 1 |
| Battaini, F | 1 |
| Galli, C | 1 |
| Tremoli, E | 1 |
| Gong, G | 1 |
| Waris, G | 1 |
| Tanveer, R | 1 |
| Siddiqui, A | 1 |
| Semenova, LP | 1 |
| Nikol'skaia, TA | 1 |
| Emanuel', NM | 1 |
15 other studies available for gallic acid and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Cytotoxic activity of strawberry tree (
Topics: Antineoplastic Agents; Antioxidants; Biphenyl Compounds; Caco-2 Cells; Carcinoma, Hepatocellular; Ca | 2022 |
The effect of natural polyphenols Resveratrol, Gallic acid, and Kuromanin chloride on human telomerase reverse transcriptase (hTERT) expression in HepG2 hepatocellular carcinoma: role of SIRT1/Nrf2 signaling pathway and oxidative stress.
Topics: Carcinoma, Hepatocellular; Chlorides; Gallic Acid; Humans; Liver Neoplasms; NF-E2-Related Factor 2; | 2023 |
Phytochemical gallic acid alleviates nonalcoholic fatty liver disease via AMPK-ACC-PPARa axis through dual regulation of lipid metabolism and mitochondrial function.
Topics: AMP-Activated Protein Kinases; Animals; Carcinoma, Hepatocellular; Gallic Acid; Humans; Lipid Metabo | 2023 |
Methyl gallate, gallic acid-derived compound, inhibit cell proliferation through increasing ROS production and apoptosis in hepatocellular carcinoma cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Carcinoma, Hepatocell | 2021 |
Gallic acid against hepatocellular carcinoma: An integrated scheme of the potential mechanisms of action from in vivo study.
Topics: alpha-Fetoproteins; Animals; Apoptosis; Biomarkers, Tumor; Carcinoma, Hepatocellular; Diethylnitrosa | 2017 |
Improving Anti-Cancer Potentiality and Bioavailability of Gallic Acid by Designing Polymeric Nanocomposite Formulation
Topics: Animals; Biological Availability; Carcinoma, Hepatocellular; Diethylnitrosamine; Drug Compounding; F | 2018 |
Pro-apoptotic and cytotoxic effects of enriched fraction of Elytranthe parasitica (L.) Danser against HepG2 Hepatocellular carcinoma.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Survival; Gallic Acid; | 2016 |
Antiproliferative potential of gallic acid against diethylnitrosamine-induced rat hepatocellular carcinoma.
Topics: Alkylating Agents; Animals; Antioxidants; Biomarkers, Tumor; Carcinogens; Carcinoma, Hepatocellular; | 2008 |
[The effect of gallic acid extracted from leaves of Phyllanthus emblica on apoptosis of human hepatocellular carcinoma BEL-7404 cells].
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Prol | 2009 |
[Study of galic acid extracted from the leaves of Phyllanthus emblica on apoptotic mechanism of human hepatocellular carcinoma cells BEL-7404].
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Carcino | 2011 |
Genotoxic and antigenotoxic effects of catechin and tannins from the bark of Hamamelis virginiana L. in metabolically competent, human hepatoma cells (Hep G2) using single cell gel electrophoresis.
Topics: Anthocyanins; Antineoplastic Agents, Phytogenic; Benzo(a)pyrene; Carcinoma, Hepatocellular; Catechin | 2003 |
Induction of phenolsulfotransferase expression by phenolic acids in human hepatoma HepG2 cells.
Topics: Arylsulfotransferase; Carcinoma, Hepatocellular; Cell Division; Enzyme Induction; Gallic Acid; Gene | 2005 |
Very low density lipoprotein-mediated signal transduction and plasminogen activator inhibitor type 1 in cultured HepG2 cells.
Topics: Antioxidants; Arachidonic Acid; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinas | 1999 |
Human hepatitis C virus NS5A protein alters intracellular calcium levels, induces oxidative stress, and activates STAT-3 and NF-kappa B.
Topics: Acetylcysteine; Antioxidants; Calcium; Calcium Signaling; Carcinoma, Hepatocellular; Chelating Agent | 2001 |
[Oxidation phosphorylation and respiration in liver mitochondria and solid hepatoma of mice suppressed by propylgallate].
Topics: Animals; Antioxidants; Carcinoma, Hepatocellular; Gallic Acid; Liver Neoplasms; Mice; Neoplasms, Exp | 1965 |