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gallic acid and Cancer of Lung

gallic acid has been researched along with Cancer of Lung in 31 studies

gallate : A trihydroxybenzoate that is the conjugate base of gallic acid.

Research Excerpts

ExcerptRelevanceReference
"Lung adenomas were induced in strain A mice by chronic treatment with N-nitroso compounds (given in drinking water) and with amines or ureas in food plus NaNO2 in drinking water."7.65Induction of mouse lung adenomas by amines or ureas plus nitrite and by N-nitroso compounds: effect of ascorbate, gallic acid, thiocyanate, and caffeine. ( Cardesa, A; Mirvish, SS; Shubik, P; Wallcave, L, 1975)
"Gallic acid reduced the viability of Malignant Mesothelioma cells in a concentration and time-dependent manner."5.43EGFR-dependent signalling reduced and p38 dependent apoptosis required by Gallic acid in Malignant Mesothelioma cells. ( Ayvali, N; Candemir, G; Demiroglu-Zergeroglu, A; Sagir, F; Turhanlar, E, 2016)
"Although multiple studies have revealed that gallic acid plays an important role in the inhibition of malignant transformation, cancer development, and inflammation, the molecular mechanism of gallic acid in inflammatory diseases is still unclear."3.75Gallic acid suppresses lipopolysaccharide-induced nuclear factor-kappaB signaling by preventing RelA acetylation in A549 lung cancer cells. ( Choi, KC; Jun, WJ; Jung, MG; Kim, MJ; Kwon, SH; Lee, J; Lee, JM; Lee, YH; Yoon, HG, 2009)
"The apoptosis-inducing effect of gallic acid (3,4,5-trihydroxybenzoic acid) was investigated in four human lung cancer cell lines, SBC-3 (small cell carcinoma), EBC-1 (squamous cell carcinoma), A549 (adenocarcinoma) and SBC-3/CDDP (cisplatin-resistant subclone of SBC-3)."3.70Induction of apoptosis by gallic acid in lung cancer cells. ( Akao, S; Fujiwara, H; Fujiwara, T; Fukuda, K; Gotou, K; Maruyama, R; Ohno, Y; Takemura, G; Toyota, M; Watanabe, M; Xinbin, Q; Yasuda, N, 1999)
"Lung adenomas were induced in strain A mice by chronic treatment with N-nitroso compounds (given in drinking water) and with amines or ureas in food plus NaNO2 in drinking water."3.65Induction of mouse lung adenomas by amines or ureas plus nitrite and by N-nitroso compounds: effect of ascorbate, gallic acid, thiocyanate, and caffeine. ( Cardesa, A; Mirvish, SS; Shubik, P; Wallcave, L, 1975)
"Lung cancer is one of the most aggressive forms of cancer that leads to a high mortality rate amongst several cancer types and it is a widely recurrent cancer globally."1.56Therapeutic Potential of Zinc Oxide-Loaded Syringic Acid Against in vitro and in vivo Model of Lung Cancer. ( Qi, L; Qiu, F; Yang, N; Zhu, F, 2020)
"Metastasis is the main cause of cancer-related death and requires the development of effective treatments with reduced toxicity and effective anticancer activity."1.46Solid lipid nanoparticles improve octyl gallate antimetastatic activity and ameliorate its renal and hepatic toxic effects. ( Cordova, CAS; Creczynski-Pasa, TB; Jasper, R; Locatelli, C; Mascarello, A; Nunes, RJ; Silva, AH; Winter, E; Yunes, RA; Zanetti-Ramos, BG, 2017)
"Lung cancer is one of the most of cancer type founds and a leading cause of death worldwide."1.46Nanogold-Gallate Chitosan-Targeted Pulmonary Delivery for Treatment of Lung Cancer. ( Ekgasit, S; Komenek, S; Luesakul, U; Muangsin, N; Praphairaksit, N; Puthong, S; Vilaivan, T, 2017)
"Treatment with gallic acid resulted in a significant reduction in proliferation and induction of apoptosis, only in EGFR-mutant NSCLC cells."1.43Gallic acid induces apoptosis in EGFR-mutant non-small cell lung cancers by accelerating EGFR turnover. ( Nam, B; Rho, JK; Shin, DM; Son, J, 2016)
"Gallic acid reduced the viability of Malignant Mesothelioma cells in a concentration and time-dependent manner."1.43EGFR-dependent signalling reduced and p38 dependent apoptosis required by Gallic acid in Malignant Mesothelioma cells. ( Ayvali, N; Candemir, G; Demiroglu-Zergeroglu, A; Sagir, F; Turhanlar, E, 2016)
" It was observed that C(14) decreased lung metastasis in vivo by 80% and increased the survival rate of the animals without toxic effects."1.38Antimetastatic activity and low systemic toxicity of tetradecyl gallate in a preclinical melanoma mouse model. ( Carvalho, DR; Creczynski-Pasa, TB; de Cordova, CA; Locatelli, C; Mascarello, A; Nunes, RJ; Pilati, C; Yunes, RA, 2012)
" From this active fraction, seven compounds have been isolated and four compounds (pinosylvin, galangin, quercetin and methyl gallate) have been examined for their dose-response effect on the viability of A549 cells and on TNF-α inhibitory activity."1.37Bioactivity guided isolation of anticancer constituents from leaves of Alnus sieboldiana (Betulaceae). ( Asakawa, Y; Kuzuhara, T; Ludwiczuk, A; Saha, A, 2011)
"We utilized two tumoral models: Ehrlich ascites tumor cells (EAT)/BALB/c mice and Lewis lung cancer cells (LLC1)/C57bl/6 mice."1.35Chemotherapeutic potential of two gallic acid derivative compounds from leaves of Casearia sylvestris Sw (Flacourtiaceae). ( Chaar, Jda S; Da Silva, SL; Yano, T, 2009)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.23)18.7374
1990's2 (6.45)18.2507
2000's5 (16.13)29.6817
2010's19 (61.29)24.3611
2020's4 (12.90)2.80

Authors

AuthorsStudies
Nam, B1
Rho, JK2
Shin, DM1
Son, J1
Yadav, DK1
Bhadresha, K1
Rao, P1
Shaikh, S1
Rawal, RM1
Tan, YJ1
Ali, A1
Tee, SY1
Teo, JT1
Xi, Y1
Go, ML1
Lam, Y1
Gupta, N1
Bhagat, S1
Singh, M1
Jangid, AK1
Bansal, V1
Singh, S1
Pooja, D1
Kulhari, H1
Wang, D1
Bao, B1
Yang, N1
Qiu, F1
Zhu, F1
Qi, L1
Cordova, CAS1
Locatelli, C2
Winter, E1
Silva, AH1
Zanetti-Ramos, BG1
Jasper, R1
Mascarello, A2
Yunes, RA2
Nunes, RJ2
Creczynski-Pasa, TB2
Maimaiti, A1
Aili, A1
Kuerban, H1
Li, X1
Sunil Gowda, SN1
Rajasowmiya, S1
Vadivel, V1
Banu Devi, S1
Celestin Jerald, A1
Marimuthu, S1
Devipriya, N1
Zhang, T1
Ma, L2
Wu, P1
Li, W2
Li, T1
Gu, R1
Dan, X1
Li, Z1
Fan, X1
Xiao, Z1
Park, WH3
Kim, SH2
Gao, Y1
Jia, L1
Li, B1
Chen, YC1
Tu, Y1
Jin, P1
Zhu, FX1
Tan, XB1
Liu, WB1
Jin, X1
Feng, L1
Jia, XB1
Mao, F1
Zhang, L1
Cai, MH1
Guo, H1
Yuan, HH1
Park, J1
Shim, MK1
Jin, M1
Rhyu, MR1
Lee, Y1
Wang, R1
Weng, D1
Yao, J1
Liu, X1
Jin, F1
Phan, AN1
Hua, TN1
Kim, MK1
Vo, VT1
Choi, JW1
Kim, HW1
Kim, KW1
Jeong, Y1
Komenek, S1
Luesakul, U1
Ekgasit, S1
Vilaivan, T1
Praphairaksit, N1
Puthong, S1
Muangsin, N1
Demiroglu-Zergeroglu, A1
Candemir, G1
Turhanlar, E1
Sagir, F1
Ayvali, N1
Da Silva, SL1
Chaar, Jda S1
Yano, T1
Park, YS1
Towantakavanit, K1
Kowalska, T1
Jung, ST1
Ham, KS1
Heo, BG1
Cho, JY1
Yun, JG1
Kim, HJ1
Gorinstein, S1
Choi, KC1
Lee, YH1
Jung, MG1
Kwon, SH1
Kim, MJ1
Jun, WJ1
Lee, J1
Lee, JM1
Yoon, HG1
Ji, BC1
Hsu, WH1
Yang, JS1
Hsia, TC1
Lu, CC1
Chiang, JH1
Yang, JL1
Lin, CH1
Lin, JJ1
Suen, LJ1
Gibson Wood, W1
Chung, JG1
You, BR2
Ludwiczuk, A1
Saha, A1
Kuzuhara, T1
Asakawa, Y1
Carvalho, DR1
de Cordova, CA1
Pilati, C1
Kim, SZ1
Sazuka, M1
Imazawa, H1
Shoji, Y1
Mita, T1
Hara, Y1
Isemura, M1
Ohno, Y2
Fukuda, K2
Takemura, G2
Toyota, M1
Watanabe, M2
Yasuda, N2
Xinbin, Q1
Maruyama, R1
Akao, S2
Gotou, K1
Fujiwara, T1
Fujiwara, H2
Kawada, M1
Ri, Y1
Ikoma, T1
Yuugetu, H1
Asai, T1
Minatoguchi, S1
Gotoh, K1
Mirvish, SS1
Cardesa, A1
Wallcave, L1
Shubik, P1

Other Studies

31 other studies available for gallic acid and Cancer of Lung

ArticleYear
Gallic acid induces apoptosis in EGFR-mutant non-small cell lung cancers by accelerating EGFR turnover.
    Bioorganic & medicinal chemistry letters, 2016, 10-01, Volume: 26, Issue:19

    Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; ErbB Receptors; Gallic Acid; Humans; Lu

2016
Identification of hub genes associated with prognosis of lung cancer via integrated bioinformatics and
    Journal of biomolecular structure & dynamics, 2023, Volume: 41, Issue:20

    Topics: Biomarkers, Tumor; Computational Biology; Female; Gallic Acid; Gene Expression Profiling; Gene Expre

2023
Galloyl esters of trans-stilbenes are inhibitors of FASN with anticancer activity on non-small cell lung cancer cells.
    European journal of medicinal chemistry, 2019, Nov-15, Volume: 182

    Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Su

2019
Site-specific delivery of a natural chemotherapeutic agent to human lung cancer cells using biotinylated 2D rGO nanocarriers.
    Materials science & engineering. C, Materials for biological applications, 2020, Volume: 112

    Topics: A549 Cells; Antineoplastic Agents; Biotinylation; Cell Survival; Coumarins; Drug Carriers; Endocytos

2020
Gallic Acid Impedes Non-Small Cell Lung Cancer Progression via Suppression of EGFR-Dependent CARM1-PELP1 Complex.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; CARD Signaling Adaptor Proteins; Cell Movemen

2020
Therapeutic Potential of Zinc Oxide-Loaded Syringic Acid Against in vitro and in vivo Model of Lung Cancer.
    International journal of nanomedicine, 2020, Volume: 15

    Topics: A549 Cells; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Benzo(a)pyrene; Female; Gallic Ac

2020
Solid lipid nanoparticles improve octyl gallate antimetastatic activity and ameliorate its renal and hepatic toxic effects.
    Anti-cancer drugs, 2017, Volume: 28, Issue:9

    Topics: Animals; Chemical and Drug Induced Liver Injury; Chlorocebus aethiops; Female; Gallic Acid; Kidney D

2017
VDAC1 Mediated Anticancer Activity of Gallic Acid in Human Lung Adenocarcinoma A549 Cells.
    Anti-cancer agents in medicinal chemistry, 2018, Volume: 18, Issue:2

    Topics: A549 Cells; Adenocarcinoma of Lung; Antineoplastic Agents; Cell Proliferation; Cell Survival; Dose-R

2018
Gallic acid-coated sliver nanoparticle alters the expression of radiation-induced epithelial-mesenchymal transition in non-small lung cancer cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2018, Volume: 52

    Topics: A549 Cells; Antigens, CD; Cadherins; Carcinoma, Non-Small-Cell Lung; Cell Survival; Epithelial-Mesen

2018
Gallic acid has anticancer activity and enhances the anticancer effects of cisplatin in non‑small cell lung cancer A549 cells via the JAK/STAT3 signaling pathway.
    Oncology reports, 2019, Volume: 41, Issue:3

    Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell

2019
MAPK inhibitors augment gallic acid-induced A549 lung cancer cell death through the enhancement of glutathione depletion.
    Oncology reports, 2013, Volume: 30, Issue:1

    Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Gallic Acid; Glutathione; Humans; JNK Mitogen-Activ

2013
Enhancement of (-)-epigallocatechin-3-gallate and theaflavin-3-3'-digallate induced apoptosis by ascorbic acid in human lung adenocarcinoma SPC-A-1 cells and esophageal carcinoma Eca-109 cells via MAPK pathways.
    Biochemical and biophysical research communications, 2013, Aug-23, Volume: 438, Issue:2

    Topics: Adenocarcinoma; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Ascorbic Acid; Biflavonoi

2013
[Study on effective substances of tea for chemoprevention of lung cancer based on principal component analysis].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2013, Volume: 36, Issue:6

    Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Bronchi; Catechin; Cell Survival; Cells,

2013
Leonurine hydrochloride induces apoptosis of H292 lung cancer cell by a mitochondria-dependent pathway.
    Pharmaceutical biology, 2015, Volume: 53, Issue:11

    Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Gallic Acid; Huma

2015
Methyl syringate, a TRPA1 agonist represses hypoxia-induced cyclooxygenase-2 in lung cancer cells.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2016, Mar-15, Volume: 23, Issue:3

    Topics: Calcium Channels; Cell Hypoxia; Cell Line, Tumor; Cell Movement; Cyclooxygenase 2; Epithelial Cells;

2016
Gallic acid induces apoptosis and enhances the anticancer effects of cisplatin in human small cell lung cancer H446 cell line via the ROS-dependent mitochondrial apoptotic pathway.
    Oncology reports, 2016, Volume: 35, Issue:5

    Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Cell

2016
Gallic acid inhibition of Src-Stat3 signaling overcomes acquired resistance to EGF receptor tyrosine kinase inhibitors in advanced non-small cell lung cancer.
    Oncotarget, 2016, Aug-23, Volume: 7, Issue:34

    Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drug Resistance, Neoplasm; ErbB Receptors

2016
Nanogold-Gallate Chitosan-Targeted Pulmonary Delivery for Treatment of Lung Cancer.
    AAPS PharmSciTech, 2017, Volume: 18, Issue:4

    Topics: Antineoplastic Agents; Biocompatible Materials; Chitosan; Cisplatin; Drug Delivery Systems; Excipien

2017
EGFR-dependent signalling reduced and p38 dependent apoptosis required by Gallic acid in Malignant Mesothelioma cells.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 84

    Topics: Apoptosis; Cell Line, Tumor; Cell Survival; ErbB Receptors; Gallic Acid; Humans; Lung Neoplasms; Mes

2016
Chemotherapeutic potential of two gallic acid derivative compounds from leaves of Casearia sylvestris Sw (Flacourtiaceae).
    European journal of pharmacology, 2009, Apr-17, Volume: 608, Issue:1-3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Ehrlich Tumor; Carcinoma, Lewis Lung; Caseari

2009
Bioactive compounds and antioxidant and antiproliferative activities of Korean white lotus cultivars.
    Journal of medicinal food, 2009, Volume: 12, Issue:5

    Topics: Amino Acids; Antineoplastic Agents, Phytogenic; Antioxidants; Ascorbic Acid; Cell Line, Tumor; Cell

2009
Gallic acid suppresses lipopolysaccharide-induced nuclear factor-kappaB signaling by preventing RelA acetylation in A549 lung cancer cells.
    Molecular cancer research : MCR, 2009, Volume: 7, Issue:12

    Topics: Acetylation; Animals; Apoptosis; Cell Line, Tumor; Cell Survival; E1A-Associated p300 Protein; Enzym

2009
Gallic acid induces apoptosis via caspase-3 and mitochondrion-dependent pathways in vitro and suppresses lung xenograft tumor growth in vivo.
    Journal of agricultural and food chemistry, 2009, Aug-26, Volume: 57, Issue:16

    Topics: Apoptosis; bcl-2-Associated X Protein; Carcinoma, Non-Small-Cell Lung; Caspase 3; Cell Line, Tumor;

2009
Gallic acid-induced lung cancer cell death is related to glutathione depletion as well as reactive oxygen species increase.
    Toxicology in vitro : an international journal published in association with BIBRA, 2010, Volume: 24, Issue:5

    Topics: Acetylcysteine; Antineoplastic Agents; Ascorbic Acid; Buthionine Sulfoximine; Cell Death; Cell Line,

2010
Bioactivity guided isolation of anticancer constituents from leaves of Alnus sieboldiana (Betulaceae).
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2011, Apr-15, Volume: 18, Issue:6

    Topics: Alnus; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Dose-Response R

2011
Antimetastatic activity and low systemic toxicity of tetradecyl gallate in a preclinical melanoma mouse model.
    Investigational new drugs, 2012, Volume: 30, Issue:3

    Topics: Animals; Antineoplastic Agents; Cell Adhesion; Cell Survival; Female; Gallic Acid; Intercellular Adh

2012
Gallic acid-induced lung cancer cell death is accompanied by ROS increase and glutathione depletion.
    Molecular and cellular biochemistry, 2011, Volume: 357, Issue:1-2

    Topics: Apoptosis; Caspase Inhibitors; Cell Line, Tumor; Fibroblasts; Gallic Acid; Glutathione; Humans; Lung

2011
Inhibition of collagenases from mouse lung carcinoma cells by green tea catechins and black tea theaflavins.
    Bioscience, biotechnology, and biochemistry, 1997, Volume: 61, Issue:9

    Topics: Animals; Antioxidants; Biflavonoids; Carcinoma; Catechin; Free Radical Scavengers; Gallic Acid; Lung

1997
Induction of apoptosis by gallic acid in lung cancer cells.
    Anti-cancer drugs, 1999, Volume: 10, Issue:9

    Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Carcinoma, Small Cell; Carcinoma, Squamous Cell; C

1999
Anti-tumor effect of gallic acid on LL-2 lung cancer cells transplanted in mice.
    Anti-cancer drugs, 2001, Volume: 12, Issue:10

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Survival; Cisplatin; DNA, N

2001
Induction of mouse lung adenomas by amines or ureas plus nitrite and by N-nitroso compounds: effect of ascorbate, gallic acid, thiocyanate, and caffeine.
    Journal of the National Cancer Institute, 1975, Volume: 55, Issue:3

    Topics: Adenoma; Amines; Animals; Ascorbic Acid; Caffeine; Dose-Response Relationship, Drug; Gallic Acid; Lu

1975