gallic acid has been researched along with Cancer of Colon in 22 studies
gallate : A trihydroxybenzoate that is the conjugate base of gallic acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gallic acid (GA) is a natural polyphenol, which exhibits a broad spectrum of biological activities, but its therapeutic application was limited due to poor bioavailability and toxicity." | 5.62 | Surface modified PAMAM dendrimers with gallic acid inhibit, cell proliferation, cell migration and inflammatory response to augment apoptotic cell death in human colon carcinoma cells. ( Kumar, A; Pathak, C; Priyadarshi, K; Sharma, A; Shirsath, K; Waghela, NB, 2021) |
| " We investigated the effectivity of jaboticaba whole fruit ethanolic extract (FEX) in suppressing aberrant crypt foci (ACF), the earliest lesion of colorectal cancer (CRC), in 1,2-dimethylhydrazine (DMH)-induced rats and the underlying mechanisms related to the gut microbiota composition and short chain fatty acid (SCFA)." | 4.31 | Jaboticaba (Myrciaria cauliflora) Fruit Extract Suppressed Aberrant Crypt Formation in 1,2-Dimetylhydrazine-Induced Rats. ( Ardanareswari, K; Chung, YC; Liao, JW; Lowisia, W; Soedarini, B, 2023) |
| "In vitro treatment of HCT-116 colon cancer cells with 3,4-DHPAA and EGCG exhibited an additive antiproliferative effect, while methylation of 3,4-DHPAA was significantly decreased." | 2.78 | Phenolic acid concentrations in plasma and urine from men consuming green or black tea and potential chemopreventive properties for colon cancer. ( Abgaryan, N; Aronson, WJ; Carpenter, CL; de Oliveira, DM; Heber, D; Henning, SM; Lee, RP; Vicinanza, R; Wang, P; Zhang, Y, 2013) |
| "Gallic acid (GA) is a natural polyphenol, which exhibits a broad spectrum of biological activities, but its therapeutic application was limited due to poor bioavailability and toxicity." | 1.62 | Surface modified PAMAM dendrimers with gallic acid inhibit, cell proliferation, cell migration and inflammatory response to augment apoptotic cell death in human colon carcinoma cells. ( Kumar, A; Pathak, C; Priyadarshi, K; Sharma, A; Shirsath, K; Waghela, NB, 2021) |
| "Gallic acid (GA) is a polyphenol widely present in tea and other plants which is popularly used in the traditional medicine of China." | 1.36 | Chemopreventive efficacy of gallic acid, an antioxidant and anticarcinogenic polyphenol, against 1,2-dimethyl hydrazine induced rat colon carcinogenesis. ( Giftson, JS; Jayanthi, S; Nalini, N, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (36.36) | 29.6817 |
| 2010's | 9 (40.91) | 24.3611 |
| 2020's | 5 (22.73) | 2.80 |
| Authors | Studies |
|---|---|
| Larsen, CA | 1 |
| Bisson, WH | 1 |
| Dashwood, RH | 1 |
| Jiang, Y | 1 |
| Pei, J | 1 |
| Zheng, Y | 1 |
| Miao, YJ | 1 |
| Duan, BZ | 1 |
| Huang, LF | 1 |
| Ardanareswari, K | 1 |
| Lowisia, W | 1 |
| Soedarini, B | 1 |
| Liao, JW | 1 |
| Chung, YC | 1 |
| Koyuncu, İ | 1 |
| Gönel, A | 1 |
| Temiz, E | 1 |
| Karaoğul, E | 1 |
| Uyar, Z | 1 |
| Priyadarshi, K | 1 |
| Shirsath, K | 1 |
| Waghela, NB | 1 |
| Sharma, A | 1 |
| Kumar, A | 1 |
| Pathak, C | 1 |
| Elendran, S | 1 |
| Muniyandy, S | 1 |
| Lee, WW | 1 |
| Palanisamy, UD | 1 |
| Demir, S | 1 |
| Yaman, SO | 1 |
| Sener, SO | 1 |
| Ayazoglu Demir, E | 1 |
| Aliyazicioglu, R | 1 |
| Ozgen, U | 1 |
| Mentese, A | 1 |
| Deger, O | 1 |
| Aliyazicioglu, Y | 1 |
| Subramanian, AP | 1 |
| Jaganathan, SK | 1 |
| Mandal, M | 1 |
| Supriyanto, E | 1 |
| Muhamad, II | 1 |
| Bernhaus, A | 1 |
| Fritzer-Szekeres, M | 1 |
| Grusch, M | 1 |
| Saiko, P | 1 |
| Krupitza, G | 1 |
| Venkateswarlu, S | 1 |
| Trimurtulu, G | 1 |
| Jaeger, W | 1 |
| Szekeres, T | 1 |
| Lu, J | 1 |
| Gosslau, A | 1 |
| Liu, AY | 1 |
| Chen, KY | 1 |
| Lizárraga, D | 1 |
| Touriño, S | 1 |
| Reyes-Zurita, FJ | 1 |
| de Kok, TM | 1 |
| van Delft, JH | 1 |
| Maas, LM | 1 |
| Briedé, JJ | 1 |
| Centelles, JJ | 1 |
| Torres, JL | 2 |
| Cascante, M | 2 |
| Klenow, S | 2 |
| Jahns, F | 1 |
| Pool-Zobel, BL | 1 |
| Glei, M | 2 |
| Giftson, JS | 1 |
| Jayanthi, S | 2 |
| Nalini, N | 2 |
| Giftson Senapathy, J | 1 |
| Viswanathan, P | 1 |
| Umadevi, P | 1 |
| Khaledi, H | 1 |
| Alhadi, AA | 1 |
| Yehye, WA | 1 |
| Ali, HM | 1 |
| Abdulla, MA | 1 |
| Hassandarvish, P | 1 |
| Sánchez-Tena, S | 1 |
| Fernández-Cachón, ML | 1 |
| Carreras, A | 1 |
| Mateos-Martín, ML | 1 |
| Costoya, N | 1 |
| Moyer, MP | 1 |
| Nuñez, MJ | 1 |
| González-Sarrías, A | 1 |
| Ma, H | 1 |
| Edmonds, ME | 1 |
| Seeram, NP | 1 |
| Forester, SC | 1 |
| Choy, YY | 1 |
| Waterhouse, AL | 1 |
| Oteiza, PI | 1 |
| Henning, SM | 1 |
| Wang, P | 1 |
| Abgaryan, N | 1 |
| Vicinanza, R | 1 |
| de Oliveira, DM | 1 |
| Zhang, Y | 1 |
| Lee, RP | 1 |
| Carpenter, CL | 1 |
| Aronson, WJ | 1 |
| Heber, D | 1 |
| Konishi, Y | 1 |
| Kobayashi, S | 1 |
| Shimizu, M | 1 |
| Salucci, M | 1 |
| Stivala, LA | 1 |
| Maiani, G | 1 |
| Bugianesi, R | 1 |
| Vannini, V | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact of Non Digestible Carbohydrate on Production of Phenolic Acids From Strawberry Juice[NCT03383809] | 15 participants (Actual) | Interventional | 2017-04-28 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for gallic acid and Cancer of Colon
| Article | Year |
|---|---|
Gallic Acid: A Potential Anti-Cancer Agent.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Gallic Acid; | 2022 |
1 trial available for gallic acid and Cancer of Colon
| Article | Year |
|---|---|
Phenolic acid concentrations in plasma and urine from men consuming green or black tea and potential chemopreventive properties for colon cancer.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy | 2013 |
20 other studies available for gallic acid and Cancer of Colon
| Article | Year |
|---|---|
Tea catechins inhibit hepatocyte growth factor receptor (MET kinase) activity in human colon cancer cells: kinetic and molecular docking studies.
Topics: Antineoplastic Agents; Camellia sinensis; Catechin; Cell Line, Tumor; Colonic Neoplasms; Drug Screen | 2009 |
Jaboticaba (Myrciaria cauliflora) Fruit Extract Suppressed Aberrant Crypt Formation in 1,2-Dimetylhydrazine-Induced Rats.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Butyrates; Colonic Neoplasms; Colorectal Neopla | 2023 |
Pistachio Green Hull Extract Induces Apoptosis through Multiple Signaling Pathways by Causing Oxidative Stress on Colon Cancer Cells.
Topics: Antineoplastic Agents; Apoptosis; Catechin; Cell Survival; Colonic Neoplasms; DNA Damage; Drug Scree | 2021 |
Surface modified PAMAM dendrimers with gallic acid inhibit, cell proliferation, cell migration and inflammatory response to augment apoptotic cell death in human colon carcinoma cells.
Topics: Apoptosis; Carcinoma; Cell Movement; Cell Proliferation; Colonic Neoplasms; Dendrimers; Gallic Acid; | 2021 |
Permeability of the ellagitannin geraniin and its metabolites in a human colon adenocarcinoma Caco-2 cell culture model.
Topics: Adenocarcinoma; Biological Transport; Caco-2 Cells; Cell Survival; Colonic Neoplasms; Ellagic Acid; | 2019 |
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; | 2020 |
Gallic acid induced apoptotic events in HCT-15 colon cancer cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Surviva | 2016 |
Digalloylresveratrol, a new phenolic acid derivative induces apoptosis and cell cycle arrest in human HT-29 colon cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Division; Colonic Neoplasms; Fluorouracil; Gallic | 2009 |
PCR differential display-based identification of regulator of G protein signaling 10 as the target gene in human colon cancer cells induced by black tea polyphenol theaflavin monogallate.
Topics: Biflavonoids; Caco-2 Cells; Catechin; Colonic Neoplasms; Enzyme Induction; Flavonoids; Gallic Acid; | 2008 |
Witch hazel (Hamamelis virginiana) fractions and the importance of gallate moieties--electron transfer capacities in their antitumoral properties.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasm | 2008 |
Does an extract of carob (Ceratonia siliqua L.) have chemopreventive potential related to oxidative stress and drug metabolism in human colon cells?
Topics: Adenoma; Anticarcinogenic Agents; Catalase; Cell Line, Tumor; Colonic Neoplasms; Galactans; Gallic A | 2009 |
Chemopreventive efficacy of gallic acid, an antioxidant and anticarcinogenic polyphenol, against 1,2-dimethyl hydrazine induced rat colon carcinogenesis.
Topics: 1,2-Dimethylhydrazine; alpha-Tocopherol; Animals; Anticarcinogenic Agents; Antioxidants; Ascorbic Ac | 2010 |
New insight into the influence of carob extract and gallic acid on hemin induced modulation of HT29 cell growth parameters.
Topics: Adenocarcinoma; Adult; Antioxidants; Cell Proliferation; Colonic Neoplasms; Deferoxamine; Dose-Respo | 2009 |
Effect of gallic acid on xenobiotic metabolizing enzymes in 1,2-dimethyl hydrazine induced colon carcinogenesis in Wistar rats--a chemopreventive approach.
Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Colonic Neoplasms; Enzymes; Gallic Acid; Ma | 2011 |
Antioxidant, cytotoxic activities, and structure-activity relationship of gallic acid-based indole derivatives.
Topics: Antineoplastic Agents; Antioxidants; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Female; | 2011 |
Hamamelitannin from witch hazel (Hamamelis virginiana) displays specific cytotoxic activity against colon cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Colonic Neoplasms; Drug Screening Assays, Antitumor; G | 2012 |
Maple polyphenols, ginnalins A-C, induce S- and G2/M-cell cycle arrest in colon and breast cancer cells mediated by decreasing cyclins A and D1 levels.
Topics: Acer; Breast Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Colonic Neoplasms; Cyclin A; Cycli | 2013 |
The anthocyanin metabolites gallic acid, 3-O-methylgallic acid, and 2,4,6-trihydroxybenzaldehyde decrease human colon cancer cell viability by regulating pro-oncogenic signals.
Topics: Anthocyanins; Apoptosis; Benzaldehydes; Caco-2 Cells; Cell Cycle; Cell Line, Tumor; Cell Proliferati | 2014 |
Transepithelial transport of p-coumaric acid and gallic acid in Caco-2 cell monolayers.
Topics: Adenocarcinoma; Biological Transport; Cell Line, Tumor; Cell Membrane Permeability; Chromatography, | 2003 |
Flavonoids uptake and their effect on cell cycle of human colon adenocarcinoma cells (Caco2).
Topics: Adenocarcinoma; Anticarcinogenic Agents; Antioxidants; Catechin; Cell Cycle; Cell Division; Colonic | 2002 |