gallic acid has been researched along with Brain Ischemia in 14 studies
gallate : A trihydroxybenzoate that is the conjugate base of gallic acid.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We aimed to investigate the probable protective effects of gallic acid (GA) on cognitive deficits, hippocampal long term potentiation (LTP) impairments, and molecular changes induced by cerebral ischemia/reperfusion (I/R) in rats following exposure to ambient dust storm." | 8.31 | Effects of Gallic Acid on Memory Deficits and Electrophysiological Impairments Induced by Cerebral Ischemia/Reperfusion in Rats Following Exposure to Ambient Dust Storm. ( Bavarsad, K; Dianat, M; Farbood, Y; Goudarzi, G; Jahangiri, HM; Khorsandi, LS; Khoshnam, SE; Mard, SA; Sarkaki, A, 2023) |
| " Protective effects from gallic acid (GA) in cerebral ischemia/re-perfusion-induced injury to the BBB and other sites in the brain have not yet been assessed." | 8.12 | Gallic acid attenuates cerebral ischemia/re-perfusion-induced blood-brain barrier injury by modifying polarization of microglia. ( Mao, Y; Qu, Y; Wang, L, 2022) |
| "Leonurine has been shown to trigger antioxidant responses during ischemic stroke, and nuclear factor erythroid 2-related factor 2 (Nrf-2) imparts protective effects against oxidative injury." | 7.91 | Protective effects of leonurine against ischemic stroke in mice by activating nuclear factor erythroid 2-related factor 2 pathway. ( Chen, YX; He, JN; Xie, YZ; Yang, Y; Zhang, C; Zhang, XJ, 2019) |
| "Gallic acid (GA) is a plant polyphenol that has been used against CIRI." | 5.56 | Improved Neuroprotective Effects of Gallic Acid-Loaded Chitosan Nanoparticles Against Ischemic Stroke. ( Li, D; Sun, Y; Zhao, Y; Zhu, Z, 2020) |
| "We aimed to investigate the probable protective effects of gallic acid (GA) on cognitive deficits, hippocampal long term potentiation (LTP) impairments, and molecular changes induced by cerebral ischemia/reperfusion (I/R) in rats following exposure to ambient dust storm." | 4.31 | Effects of Gallic Acid on Memory Deficits and Electrophysiological Impairments Induced by Cerebral Ischemia/Reperfusion in Rats Following Exposure to Ambient Dust Storm. ( Bavarsad, K; Dianat, M; Farbood, Y; Goudarzi, G; Jahangiri, HM; Khorsandi, LS; Khoshnam, SE; Mard, SA; Sarkaki, A, 2023) |
| " Protective effects from gallic acid (GA) in cerebral ischemia/re-perfusion-induced injury to the BBB and other sites in the brain have not yet been assessed." | 4.12 | Gallic acid attenuates cerebral ischemia/re-perfusion-induced blood-brain barrier injury by modifying polarization of microglia. ( Mao, Y; Qu, Y; Wang, L, 2022) |
| "Leonurine has been shown to trigger antioxidant responses during ischemic stroke, and nuclear factor erythroid 2-related factor 2 (Nrf-2) imparts protective effects against oxidative injury." | 3.91 | Protective effects of leonurine against ischemic stroke in mice by activating nuclear factor erythroid 2-related factor 2 pathway. ( Chen, YX; He, JN; Xie, YZ; Yang, Y; Zhang, C; Zhang, XJ, 2019) |
| "Our study revealed that syringic acid treatment in cerebral ischemia reduced oxidative stress and neuronal degeneration." | 3.81 | The protective effect of syringic acid on ischemia injury in rat brain. ( Akbal, A; Aras, AB; Coşar, M; Gökmen, F; Güven, M; Kalkan, Y; Okuyucu, A; Özkan, A; Şen, HM; Topaloğlu, N, 2015) |
| "Male Sprague-Dawley rats under permanent middle cerebral artery occlusion (pMCAO) model, randomly assigned as: model, sham, nimodipine (0." | 3.11 | The therapeutic role of Jingchuan tablet on ischaemic cerebral stroke via the HIF-1α/EPO/VEGFA signalling pathway. ( Fu, Y; Li, D; Liu, Q; Wang, H; Wang, W; Zhang, T; Zhang, Y, 2022) |
| "Ischemic stroke is a leading cause of disability and mortality worldwide." | 2.82 | Oxidative Injury in Ischemic Stroke: A Focus on NADPH Oxidase 4. ( Gu, J; Huang, K; Li, G; Pan, J; Shen, J; Wang, F; Wu, F; Wu, X; Xu, K; Ye, C; Zhang, T; Zhu, Y, 2022) |
| "Leonurine (Leo) has been found to have neuroprotective effects against cerebral ischemic injury." | 1.72 | Leonurine Reduces Oxidative Stress and Provides Neuroprotection against Ischemic Injury via Modulating Oxidative and NO/NOS Pathway. ( Deng, Z; Fan, K; Li, D; Li, J; Ma, Y; Tang, X; Wang, Y; Wu, S, 2022) |
| "Ischemic stroke is a leading cause of death worldwide, and it remains an urgent task to develop novel and alternative therapeutic strategies for the disease." | 1.72 | Discovery of anti-stroke active substances in Guhong injection based on multi-phenotypic screening of zebrafish. ( Li, X; Sheng, H; Wang, Y; Wu, H; Zhao, L, 2022) |
| "Gallic acid (GA) is a plant polyphenol that has been used against CIRI." | 1.56 | Improved Neuroprotective Effects of Gallic Acid-Loaded Chitosan Nanoparticles Against Ischemic Stroke. ( Li, D; Sun, Y; Zhao, Y; Zhu, Z, 2020) |
| " Furthermore, chronic administration of GA significantly restored the spatial memory, total thiol and GPx contents and also decreased MDA levels in these tissues." | 1.40 | Protective effects of gallic acid against chronic cerebral hypoperfusion-induced cognitive deficit and brain oxidative damage in rats. ( Farbood, Y; Fathi Moghaddam, H; Korani, MS; Sarkaki, A; Taghi Mansouri, M, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 7 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, G | 1 |
| Ye, C | 1 |
| Zhu, Y | 1 |
| Zhang, T | 2 |
| Gu, J | 1 |
| Pan, J | 1 |
| Wang, F | 1 |
| Wu, F | 1 |
| Huang, K | 1 |
| Xu, K | 1 |
| Wu, X | 1 |
| Shen, J | 1 |
| Qu, Y | 1 |
| Wang, L | 1 |
| Mao, Y | 1 |
| Deng, Z | 1 |
| Li, J | 1 |
| Tang, X | 1 |
| Li, D | 3 |
| Wang, Y | 4 |
| Wu, S | 1 |
| Fan, K | 1 |
| Ma, Y | 1 |
| Wu, H | 1 |
| Sheng, H | 1 |
| Li, X | 1 |
| Zhao, L | 1 |
| Zhang, Y | 1 |
| Liu, Q | 1 |
| Wang, H | 1 |
| Fu, Y | 1 |
| Wang, W | 1 |
| Bavarsad, K | 1 |
| Farbood, Y | 2 |
| Mard, SA | 1 |
| Khoshnam, SE | 1 |
| Dianat, M | 1 |
| Jahangiri, HM | 1 |
| Khorsandi, LS | 1 |
| Goudarzi, G | 1 |
| Sarkaki, A | 2 |
| Zhao, Y | 1 |
| Zhu, Z | 1 |
| Sun, Y | 1 |
| Xie, YZ | 1 |
| Zhang, XJ | 1 |
| Zhang, C | 1 |
| Yang, Y | 1 |
| He, JN | 1 |
| Chen, YX | 1 |
| Korani, MS | 1 |
| Fathi Moghaddam, H | 1 |
| Taghi Mansouri, M | 1 |
| Güven, M | 1 |
| Aras, AB | 1 |
| Topaloğlu, N | 1 |
| Özkan, A | 1 |
| Şen, HM | 1 |
| Kalkan, Y | 1 |
| Okuyucu, A | 1 |
| Akbal, A | 1 |
| Gökmen, F | 1 |
| Coşar, M | 1 |
| Qi, J | 1 |
| Hong, ZY | 1 |
| Xin, H | 1 |
| Zhu, YZ | 1 |
| Cai, F | 1 |
| Li, C | 1 |
| Wu, J | 1 |
| Min, Q | 1 |
| Ouyang, C | 1 |
| Zheng, M | 1 |
| Ma, S | 1 |
| Yu, W | 1 |
| Lin, F | 1 |
| Chiou, GC | 1 |
| Hong, SJ | 2 |
| Hwang, JH | 1 |
1 review available for gallic acid and Brain Ischemia
| Article | Year |
|---|---|
Oxidative Injury in Ischemic Stroke: A Focus on NADPH Oxidase 4.
Topics: Animals; Betulinic Acid; Brain Ischemia; Drug Therapy, Combination; Electroacupuncture; Gallic Acid; | 2022 |
1 trial available for gallic acid and Brain Ischemia
| Article | Year |
|---|---|
The therapeutic role of Jingchuan tablet on ischaemic cerebral stroke via the HIF-1α/EPO/VEGFA signalling pathway.
Topics: Animals; Brain Ischemia; Chlorogenic Acid; Disease Models, Animal; Gallic Acid; Infarction, Middle C | 2022 |
12 other studies available for gallic acid and Brain Ischemia
| Article | Year |
|---|---|
Gallic acid attenuates cerebral ischemia/re-perfusion-induced blood-brain barrier injury by modifying polarization of microglia.
Topics: Animals; Blood-Brain Barrier; Brain Ischemia; Gallic Acid; Infarction, Middle Cerebral Artery; Mice; | 2022 |
Leonurine Reduces Oxidative Stress and Provides Neuroprotection against Ischemic Injury via Modulating Oxidative and NO/NOS Pathway.
Topics: Animals; Apoptosis; Brain Ischemia; Gallic Acid; Glucose; Ischemia; Neuroprotection; Neuroprotective | 2022 |
Discovery of anti-stroke active substances in Guhong injection based on multi-phenotypic screening of zebrafish.
Topics: Animals; Brain Ischemia; Chlorogenic Acid; Cytokines; Gallic Acid; Ischemic Stroke; Mice; Molecular | 2022 |
Effects of Gallic Acid on Memory Deficits and Electrophysiological Impairments Induced by Cerebral Ischemia/Reperfusion in Rats Following Exposure to Ambient Dust Storm.
Topics: Animals; Brain Ischemia; Dust; Gallic Acid; Hippocampus; Memory Disorders; MicroRNAs; Rats; Rats, Wi | 2023 |
Improved Neuroprotective Effects of Gallic Acid-Loaded Chitosan Nanoparticles Against Ischemic Stroke.
Topics: Animals; Apoptosis; Brain Ischemia; Chitosan; Gallic Acid; Ischemic Stroke; Male; Nanoparticles; Neu | 2020 |
Protective effects of leonurine against ischemic stroke in mice by activating nuclear factor erythroid 2-related factor 2 pathway.
Topics: Animals; Brain Ischemia; Gallic Acid; Male; Mice; Mice, Inbred ICR; Mice, Knockout; Neuroprotective | 2019 |
Protective effects of gallic acid against chronic cerebral hypoperfusion-induced cognitive deficit and brain oxidative damage in rats.
Topics: Animals; Antioxidants; Brain; Brain Ischemia; Chronic Disease; Cognition Disorders; Disease Models, | 2014 |
The protective effect of syringic acid on ischemia injury in rat brain.
Topics: Animals; Antioxidants; Apoptosis; Brain; Brain Ischemia; Gallic Acid; Male; Malondialdehyde; Nuclear | 2015 |
Neuroprotective effects of leonurine on ischemia/reperfusion-induced mitochondrial dysfunctions in rat cerebral cortex.
Topics: Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Brain Ischemia; Cer | 2010 |
Modulation of the oxidative stress and nuclear factor kappaB activation by theaflavin 3,3'-gallate in the rats exposed to cerebral ischemia-reperfusion.
Topics: Animals; Biflavonoids; Brain; Brain Ischemia; Catechin; Cell Extracts; Cerebral Infarction; Cyclooxy | 2007 |
Prevention and reduction of neural damage in ischemic strokes by w-(N,N'-diethylamino)-n-alkyl-3,4,5-trimethoxybenzoate compounds.
Topics: Animals; Aorta; Brain Ischemia; Calcium; Calcium Channel Blockers; Cells, Cultured; Cerebral Cortex; | 1995 |
Reduction of neuronal damage in ischemic stroke using a combination therapy of TMB-8 with L-arginine.
Topics: Animals; Arginine; Brain Ischemia; Calcium; Calcium Channel Blockers; Drug Therapy, Combination; Gal | 2000 |