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gallic acid and Atherosclerosis

gallic acid has been researched along with Atherosclerosis in 14 studies

gallate : A trihydroxybenzoate that is the conjugate base of gallic acid.

Atherosclerosis: A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.

Research Excerpts

ExcerptRelevanceReference
"Leonurine can promote cholesterol efflux and alleviate cellular lipid accumulation by magnifying the expression of ABCA1/G1 in a PPARγ/LXRα signaling pathway-dependent manner in human THP-1 macrophage-derived foam cells and abate atherogenesis in apoE-/- mice, which may offer a promising therapeutic intervention of leonurine in protecting against AS."7.85Leonurine Prevents Atherosclerosis Via Promoting the Expression of ABCA1 and ABCG1 in a Pparγ/Lxrα Signaling Pathway-Dependent Manner. ( Chen, Q; Hu, H; Jiang, T; Li, H; Lv, YC; Ren, K; Yao, R; Zhao, GJ, 2017)
"Gallic acid (GA) is a plant-derived triphenolic chemical with multiple cardio-protective properties, such as antiobesity, anti-inflammation, and antioxidation."5.72Low-Dose Gallic Acid Administration Does Not Improve Diet-Induced Metabolic Disorders and Atherosclerosis in Apoe Knockout Mice. ( An, X; Bai, J; Liao, J; Lin, QY; Liu, S; Wang, Y; Xie, Y, 2022)
"The present study aims to evaluate the ability of peonidin and petunidin-3-glucoside (Peo-3-glc and Pet-3-glc) and their metabolites (vanillic acid; VA and methyl-gallic acid; MetGA), to prevent monocyte (THP-1) adhesion to endothelial cells (HUVECs), and to reduce the production of vascular cell adhesion molecule (VCAM)-1, E-selectin and vascular endothelial growth factor (VEGF) in a stimulated pro-inflammatory environment, a pivotal step of atherogenesis."3.96Modulation of Adhesion Process, E-Selectin and VEGF Production by Anthocyanins and Their Metabolites in an ( Del Bo', C; Klimis-Zacas, D; Marino, M; Porrini, M; Riso, P; Tucci, M, 2020)
"Leonurine can promote cholesterol efflux and alleviate cellular lipid accumulation by magnifying the expression of ABCA1/G1 in a PPARγ/LXRα signaling pathway-dependent manner in human THP-1 macrophage-derived foam cells and abate atherogenesis in apoE-/- mice, which may offer a promising therapeutic intervention of leonurine in protecting against AS."3.85Leonurine Prevents Atherosclerosis Via Promoting the Expression of ABCA1 and ABCG1 in a Pparγ/Lxrα Signaling Pathway-Dependent Manner. ( Chen, Q; Hu, H; Jiang, T; Li, H; Lv, YC; Ren, K; Yao, R; Zhao, GJ, 2017)
"To investigate SCM-198 (also known as "leonurine"), a compound in Herba leonuri, as well as its effect on the progression of atherosclerosis in hypercholesterolemic rabbits and underlying mechanisms."3.78SCM-198 attenuates early atherosclerotic lesions in hypercholesterolemic rabbits via modulation of the inflammatory and oxidative stress pathways. ( Guo, W; Liu, H; Wen, Y; Wu, J; Xiong, Q; Zhang, Y; Zhu, Y; Zou, Y, 2012)
"Gallic acid (GA) is a plant-derived triphenolic chemical with multiple cardio-protective properties, such as antiobesity, anti-inflammation, and antioxidation."1.72Low-Dose Gallic Acid Administration Does Not Improve Diet-Induced Metabolic Disorders and Atherosclerosis in Apoe Knockout Mice. ( An, X; Bai, J; Liao, J; Lin, QY; Liu, S; Wang, Y; Xie, Y, 2022)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (7.14)29.6817
2010's8 (57.14)24.3611
2020's5 (35.71)2.80

Authors

AuthorsStudies
Bai, J1
Lin, QY1
An, X1
Liu, S1
Wang, Y1
Xie, Y1
Liao, J1
Clark, M1
Centner, AM1
Ukhanov, V1
Nagpal, R1
Salazar, G1
Marino, M1
Del Bo', C3
Tucci, M1
Klimis-Zacas, D1
Riso, P3
Porrini, M3
Ning, K1
Wang, MJ1
Lin, G1
Zhang, YL1
Li, MY1
Yang, BF1
Chen, Y1
Huang, Y1
Li, ZM1
Huang, YJ1
Zhu, L1
Liang, K1
Yu, B1
Zhu, YZ2
Zhu, YC1
Liu, W1
Liu, J1
Xing, S1
Pan, X1
Wei, S1
Zhou, M1
Li, Z1
Wang, L1
Bielicki, JK1
Jiang, T1
Ren, K1
Chen, Q1
Li, H1
Yao, R1
Hu, H1
Lv, YC1
Zhao, GJ1
Wu, W1
Zhu, Q1
Liu, X1
Wu, C1
Luan, H1
Zhang, X2
Wang, S1
Sun, X1
Guo, P1
Cao, Y1
Roursgaard, M2
Loft, S2
Møller, P2
Takahashi, Y1
Otsuki, A1
Mori, Y1
Kawakami, Y1
Ito, H1
Norata, GD1
Catapano, AL1
Zhang, Y1
Guo, W1
Wen, Y1
Xiong, Q1
Liu, H1
Wu, J1
Zou, Y1
Zhu, Y1
Lee, G1
Na, HJ1
Namkoong, S1
Jeong Kwon, H1
Han, S1
Ha, KS1
Kwon, YG1
Lee, H1
Kim, YM1

Reviews

1 review available for gallic acid and Atherosclerosis

ArticleYear
Discovery of Leonuri and therapeutical applications: From bench to bedside.
    Pharmacology & therapeutics, 2018, Volume: 188

    Topics: Animals; Apoptosis; Atherosclerosis; Drug Discovery; Gallic Acid; Humans; Leonurus; Medicine, Chines

2018

Other Studies

13 other studies available for gallic acid and Atherosclerosis

ArticleYear
Low-Dose Gallic Acid Administration Does Not Improve Diet-Induced Metabolic Disorders and Atherosclerosis in Apoe Knockout Mice.
    Journal of immunology research, 2022, Volume: 2022

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Cardiovascular Diseases; Diet, High-Fat; Gallic Acid; I

2022
Gallic acid ameliorates atherosclerosis and vascular senescence and remodels the microbiome in a sex-dependent manner in ApoE
    The Journal of nutritional biochemistry, 2022, Volume: 110

    Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Diet, High-Fat; Female; Gallic Acid; Gastrointes

2022
Modulation of Adhesion Process, E-Selectin and VEGF Production by Anthocyanins and Their Metabolites in an
    Nutrients, 2020, Feb-28, Volume: 12, Issue:3

    Topics: Anthocyanins; Atherosclerosis; Cell Adhesion; Cell Death; Cell Survival; E-Selectin; Gallic Acid; Gl

2020
eNOS-Nitric Oxide System Contributes to a Novel Antiatherogenic Effect of Leonurine via Inflammation Inhibition and Plaque Stabilization.
    The Journal of pharmacology and experimental therapeutics, 2020, Volume: 373, Issue:3

    Topics: Animals; Atherosclerosis; Cell Line; Gallic Acid; Human Umbilical Vein Endothelial Cells; Humans; In

2020
The benzoate plant metabolite ethyl gallate prevents cellular- and vascular-lipid accumulation in experimental models of atherosclerosis.
    Biochemical and biophysical research communications, 2021, 06-04, Volume: 556

    Topics: Animals; Apolipoproteins E; Atherosclerosis; ATP-Binding Cassette Transporters; Benzoates; Cholester

2021
Leonurine Prevents Atherosclerosis Via Promoting the Expression of ABCA1 and ABCG1 in a Pparγ/Lxrα Signaling Pathway-Dependent Manner.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2017, Volume: 43, Issue:4

    Topics: Animals; Antioxidants; Aorta; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP Binding Casse

2017
Chlorogenic acid protects against atherosclerosis in ApoE-/- mice and promotes cholesterol efflux from RAW264.7 macrophages.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Animals; Anticholesteremic Agents; Aorta; Apolipoproteins E; Atherosclerosis; Atorvastatin; ATP Bind

2014
Anthocyanins and phenolic acids from a wild blueberry (Vaccinium angustifolium) powder counteract lipid accumulation in THP-1-derived macrophages.
    European journal of nutrition, 2016, Volume: 55, Issue:1

    Topics: Anthocyanins; Antioxidants; Atherosclerosis; Blueberry Plants; Carotenoids; Cell Line, Tumor; Cell S

2016
Inhibition of leukocyte-type 12-lipoxygenase by guava tea leaves prevents development of atherosclerosis.
    Food chemistry, 2015, Nov-01, Volume: 186

    Topics: Animals; Aorta; Apolipoproteins E; Arachidonate 12-Lipoxygenase; Atherosclerosis; Dose-Response Rela

2015
Different effects of anthocyanins and phenolic acids from wild blueberry (Vaccinium angustifolium) on monocytes adhesion to endothelial cells in a TNF-α stimulated proinflammatory environment.
    Molecular nutrition & food research, 2016, Volume: 60, Issue:11

    Topics: Anthocyanins; Atherosclerosis; Blueberry Plants; Cell Adhesion; E-Selectin; Endothelium, Vascular; G

2016
Leonurine: a new comer in the natural compounds affecting atherosclerosis.
    Atherosclerosis, 2012, Volume: 224, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Atherosclerosis; Gallic Acid; Male

2012
SCM-198 attenuates early atherosclerotic lesions in hypercholesterolemic rabbits via modulation of the inflammatory and oxidative stress pathways.
    Atherosclerosis, 2012, Volume: 224, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Atherosclerosis; Chemokine CCL2; Gallic Acid; Hyper

2012
4-O-methylgallic acid down-regulates endothelial adhesion molecule expression by inhibiting NF-kappaB-DNA-binding activity.
    European journal of pharmacology, 2006, Dec-03, Volume: 551, Issue:1-3

    Topics: Anti-Inflammatory Agents; Atherosclerosis; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured;

2006